Dengue is an arboviral disease caused by the dengue virus,with 390 million infections reported annually worldwide.It is classified into two categories:dengue without or with warning signs and severe dengue.[1]Given th...Dengue is an arboviral disease caused by the dengue virus,with 390 million infections reported annually worldwide.It is classified into two categories:dengue without or with warning signs and severe dengue.[1]Given the moderate efficacy of the dengue vaccine,[2]there is an urgent necessity to design host-directed therapeutic strategies,such as the repurposing of FDA-approved drugs,to combat dengue virus infection.展开更多
Different forms of programmed cell death have been described to participate in the degeneration of dopaminergic neurons in Parkinson’s disease(PD).Given the critical role that disturbance of mitochondrial homeostasis...Different forms of programmed cell death have been described to participate in the degeneration of dopaminergic neurons in Parkinson’s disease(PD).Given the critical role that disturbance of mitochondrial homeostasis plays in the pathogenesis of PD,apoptosis can be reasonably considered as one of the cell death pathways involved in neuronal loss(Schon and Przedborski,2011).Multiple lines of evidence support that proposal such as the observations in postmortem human brain samples of PD patients including mitochondrial complex I deficiency,reactive oxygen species generation,and oxidative damage to lipids,proteins,and DNA,among others.展开更多
We often hear statements like“the market raises expectations for central bank interest rate cuts,resulting in higher commodity prices”.Given the current situation,the People’s Bank of China might adopt a more accom...We often hear statements like“the market raises expectations for central bank interest rate cuts,resulting in higher commodity prices”.Given the current situation,the People’s Bank of China might adopt a more accommodative monetary policy to mitigate the impact of the China-U.S.trade friction.Will this further easing of the monetary environment lead to an increase in natural gas prices?展开更多
The application of the Euclidean division theorem for the positive integers allowed us to establish a set which contains all the prime numbers and this set we called it set of supposedly prime numbers and we noted it ...The application of the Euclidean division theorem for the positive integers allowed us to establish a set which contains all the prime numbers and this set we called it set of supposedly prime numbers and we noted it E<sub>sp</sub>. We subsequently established from the previous set the set of non-prime numbers (the set of numbers belonging to this set and which are not prime) denoted E<sub>np</sub>. We then extracted from the set of supposedly prime numbers the numbers which are not prime and the set of remaining number constitutes the set of prime numbers denoted E<sub>p</sub>. We have deduced from the previous set, the set of prime numbers between two natural numbers. We have explained during our demonstrations the origin of the twin prime numbers and the structure of the chain of prime numbers.展开更多
Separation and recognition of radar signals is the key function of modern radar reconnaissance,which is of great sig-nificance for electronic countermeasures and anti-countermea-sures.In order to improve the ability o...Separation and recognition of radar signals is the key function of modern radar reconnaissance,which is of great sig-nificance for electronic countermeasures and anti-countermea-sures.In order to improve the ability of separating mixed signals in complex electromagnetic environment,a blind source separa-tion algorithm based on degree of cyclostationarity(DCS)crite-rion is constructed in this paper.Firstly,the DCS criterion is con-structed by using the cyclic spectrum theory.Then the algo-rithm flow of blind source separation is designed based on DCS criterion.At the same time,Givens matrix is constructed to make the blind source separation algorithm suitable for multiple sig-nals with different cyclostationary frequencies.The feasibility of this method is further proved.The theoretical and simulation results show that the algorithm can effectively separate and re-cognize common multi-radar signals.展开更多
This study aims to investigate whether Corporate Social Responsibility(CSR)activities reduce supply chain disruptions by examining the impact of the Suez Canal obstruction on the Ever Given container ship in March 202...This study aims to investigate whether Corporate Social Responsibility(CSR)activities reduce supply chain disruptions by examining the impact of the Suez Canal obstruction on the Ever Given container ship in March 2021.This study conclude that the more responsible companies have higher returns and are less affected by this event than the less responsible companies;the less responsible companies have lower returns.The companies with better CSR have a lower impact on their supply chains when faced with disruptions in the supply chain.展开更多
基金funded by grants Pronaii 302979A1-S-9005 CONACyT (México) from RMDA。
文摘Dengue is an arboviral disease caused by the dengue virus,with 390 million infections reported annually worldwide.It is classified into two categories:dengue without or with warning signs and severe dengue.[1]Given the moderate efficacy of the dengue vaccine,[2]there is an urgent necessity to design host-directed therapeutic strategies,such as the repurposing of FDA-approved drugs,to combat dengue virus infection.
基金supported by the Spanish Ministerio de Ciencia e Innovación/Agencia Española de Investigación(PID2021-124096OB-I00)(to JLV)JGR was granted by Demensfonden,The Royal Physiografic Society of Lund,Neurofonden,The Greta och Johan Kocks stiftelser,and Bertil och Ebon Norlins stiftelse.
文摘Different forms of programmed cell death have been described to participate in the degeneration of dopaminergic neurons in Parkinson’s disease(PD).Given the critical role that disturbance of mitochondrial homeostasis plays in the pathogenesis of PD,apoptosis can be reasonably considered as one of the cell death pathways involved in neuronal loss(Schon and Przedborski,2011).Multiple lines of evidence support that proposal such as the observations in postmortem human brain samples of PD patients including mitochondrial complex I deficiency,reactive oxygen species generation,and oxidative damage to lipids,proteins,and DNA,among others.
文摘We often hear statements like“the market raises expectations for central bank interest rate cuts,resulting in higher commodity prices”.Given the current situation,the People’s Bank of China might adopt a more accommodative monetary policy to mitigate the impact of the China-U.S.trade friction.Will this further easing of the monetary environment lead to an increase in natural gas prices?
文摘The application of the Euclidean division theorem for the positive integers allowed us to establish a set which contains all the prime numbers and this set we called it set of supposedly prime numbers and we noted it E<sub>sp</sub>. We subsequently established from the previous set the set of non-prime numbers (the set of numbers belonging to this set and which are not prime) denoted E<sub>np</sub>. We then extracted from the set of supposedly prime numbers the numbers which are not prime and the set of remaining number constitutes the set of prime numbers denoted E<sub>p</sub>. We have deduced from the previous set, the set of prime numbers between two natural numbers. We have explained during our demonstrations the origin of the twin prime numbers and the structure of the chain of prime numbers.
基金supported by the National Natural Science Foundation of China(61502522).
文摘Separation and recognition of radar signals is the key function of modern radar reconnaissance,which is of great sig-nificance for electronic countermeasures and anti-countermea-sures.In order to improve the ability of separating mixed signals in complex electromagnetic environment,a blind source separa-tion algorithm based on degree of cyclostationarity(DCS)crite-rion is constructed in this paper.Firstly,the DCS criterion is con-structed by using the cyclic spectrum theory.Then the algo-rithm flow of blind source separation is designed based on DCS criterion.At the same time,Givens matrix is constructed to make the blind source separation algorithm suitable for multiple sig-nals with different cyclostationary frequencies.The feasibility of this method is further proved.The theoretical and simulation results show that the algorithm can effectively separate and re-cognize common multi-radar signals.
文摘This study aims to investigate whether Corporate Social Responsibility(CSR)activities reduce supply chain disruptions by examining the impact of the Suez Canal obstruction on the Ever Given container ship in March 2021.This study conclude that the more responsible companies have higher returns and are less affected by this event than the less responsible companies;the less responsible companies have lower returns.The companies with better CSR have a lower impact on their supply chains when faced with disruptions in the supply chain.
