Giant magnetoimpedance(GMI)sensors are increasingly employed in modern magnetic sensing technologies.However,improving the GMI performance of magnetic cores remains challenging due to intrinsic limitations in material...Giant magnetoimpedance(GMI)sensors are increasingly employed in modern magnetic sensing technologies.However,improving the GMI performance of magnetic cores remains challenging due to intrinsic limitations in material properties and structural stability.In this work,we explore the use of Joule heating to enhance the GMI response of Fe_(20)Ni_(80)/Cu composite wires.By applying a current of 1.8 A for 10 min,notable improvements in magnetic domain uniformity and a reduction in domain spacing are observed.Under these conditions,GMI ratios reach 1870% in the non-diagonal mode and1147%in the diagonal mode,respectively,highlighting their potential for applications in high-precision weak magnetic field sensing.展开更多
Background:Giant cell arteritis(GCA),the most common systemic vasculitis affecting elderly individuals,currently lacks specific therapies.This study aimed to systematically identify therapeutic targets for GCA through...Background:Giant cell arteritis(GCA),the most common systemic vasculitis affecting elderly individuals,currently lacks specific therapies.This study aimed to systematically identify therapeutic targets for GCA through integration of large-scale multi-omics datasets.Methods:We constructed a multi-stage analytical framework encompassing 32 proteomic datasets(covering 2914 unique plasma proteins)and 6 transcriptomic datasets.Multi-omics integration strategies,including two-sample Mendelian randomization,colocalization analysis,and functional enrichment analysis,were employed to identify and validate causal relationships between candidate targets and GCA risk across 4 independent European-ancestry GCA cohorts.Single-cell RNA sequencing analysis of peripheral blood mononuclear cells from untreated GCA patients was performed to characterize hub gene-immune cell relationships.Results:We identified 43 plasma proteins causally associated with GCA[false discovery rate(FDR)<0.05],with 17 representing novel therapeutic targets.Through dual validation using proteome-wide association studies and transcriptome-wide association studies,we identified 13 high-confidence candidate targets with distinct tissue-specific expression patterns.Unc-51 like kinase 3(ULK3)emerged as the strongest protective factor(odds ratio=0.47,95%confidence interval:0.37–0.71)through autophagy regulation,while SLAMF7 represents an immediate drug repositioning opportunity as the target of food and drug administration-approved elotuzumab.Five targets have existing approved drugs(SLAMF7,ICAM1,IL18,IL6ST,CTSS).Single-cell analysis revealed profound disruption of hub gene-immune cell relationships in untreated GCA patients,with cell-type-specific alterations in inflammatory gene expression,and TYMP as the most critical hub gene.Conclusions:This study provides a clinically-actionable atlas of 43 potential therapeutic targets in GCA,identifying novel mechanisms including autophagy modulation and metabolic reprogramming,with immediate drug repositioning opportunities and precision medicine strategies based on tissue-specific and cell-type-specific expression patterns.These findings require experimental validation before clinical translation.展开更多
1.Introduction As the planets closest to the outer edge of the solar system,Uranus and Neptune,namely that of ice giants,retained a significant amount of gas from the early stages of the solar system's formation.T...1.Introduction As the planets closest to the outer edge of the solar system,Uranus and Neptune,namely that of ice giants,retained a significant amount of gas from the early stages of the solar system's formation.This gas contains the physical conditions of the protostellar cloud and position information about planet formation,making ice giants important prototypes for studying both the solar system and exoplanets.展开更多
Bcakground: Pancreatic pseudocyst (PPC) is a common complication arising from acute or chronic pancreatitis, trauma, or pancreatic duct obstruction. When acute fluid collection persists for 4 - 6 weeks and is encapsul...Bcakground: Pancreatic pseudocyst (PPC) is a common complication arising from acute or chronic pancreatitis, trauma, or pancreatic duct obstruction. When acute fluid collection persists for 4 - 6 weeks and is encapsulated by a fibrous wall, it is classified as a pancreatic pseudocyst. While PPC is generally asymptomatic in many patients, it can manifest with persistent abdominal pain, dyspepsia, intra-cystic infection, and potentially lead to gastrointestinal obstruction in some cases. Although smaller PPCs may resolve spontaneously, larger PPCs tend to be refractory to absorption and often necessitate surgical intervention to prevent complications such as intracystic hemorrhage. Objective: To explore the efficacy of percutaneous catheterization with negative pressure in the treatment of large pancreatic pseudocysts. Methods: The cases of large pancreatic pseudocysts treated in our hospital from 2004 to 2022 were retrospectively collected, and the general condition, operation time, drainage time, feeding time, postoperative complications, hospital stay, cost and follow-up of the patients were analyzed. Results: A total of 132 patients with large pancreatic pseudocysts were collected. The average operation time was 32.4 ± 2.1 min;The retention time of the drainage tube was 30 ± 1.8 days in the percutaneous negative pressure drainage group;The postoperative feeding time was no fasting after local anesthesia drainage;Postoperative complications (bleeding, infection, pancreatic leakage, recurrence, anastomotic leakage, etc.): Two of the 132 patients had recurrent cysts, which were cured by re-puncture and negative pressure drainage. The length of hospital stay was 6 ± 1.1 days;The cost was 11,200 ± 1300 yuan;Follow-up: The follow-up time ranged from 1 to 3 years, and the patients had no discomfort. Conclusion: Percutaneous catheterization and negative pressure drainage can effectively treat large pancreatic pseudocysts. Compared with other treatment methods, it is simple and effective, the postoperative recovery of patients is faster, the physical damage is less, the hospital stay is shorter, and the cost is lower.展开更多
BACKGROUND Retroperitoneal liposarcoma(RPLS)is a rare malignant tumor initiated in adipocytes.It is discovered only when the tumor is large because of its deep anatomical location and insidious onset.Giant RPLS with a...BACKGROUND Retroperitoneal liposarcoma(RPLS)is a rare malignant tumor initiated in adipocytes.It is discovered only when the tumor is large because of its deep anatomical location and insidious onset.Giant RPLS with a diameter exceeding 30 cm is extremely rare.Its diagnosis and treatment present extremely great challenges.CASE SUMMARY The patient,a 62-year-old woman,presented to the hospital complaining of abdominal distension for more than six months.Imaging examination revealed a large retroperitoneal mass.Finally,the patient was diagnosed with giant RPLS.The tumor occupied the entire abdominal cavity,severely compressed the abdominal organs,and adhered tightly to the bilateral ureters.After careful preoperative preparation(including three-dimensional visualization and bilateral ureteral stent implantation),we performed resection of the large retroperitoneal mass.The tumor was completely removed and consisted of multiple masses,with a total weight of 17 kg and the largest mass size of 35 cm×28 cm×14 cm.Postoperative pathological results revealed that the mass was a well-differentiated liposarcoma.The patient recovered well after surgery,and there was no sign of recurrence after 2 months of follow-up.CONCLUSION Surgical resection is the only radical treatment for giant RPLS.Preoperative preparation is essential,and three-dimensional visualization reconstruction is helpful for the formulation of surgical plans.Postoperative radiotherapy and neoadjuvant therapy can be reasonably selected,but whether they can reduce the recurrence rate is still controversial.展开更多
As an endemic and critically-endangered wildlife species in China,the giant panda(Ailuropoda melanoleuca)has attracted widespread attention from all sectors of society regarding its survival status.In this study,the i...As an endemic and critically-endangered wildlife species in China,the giant panda(Ailuropoda melanoleuca)has attracted widespread attention from all sectors of society regarding its survival status.In this study,the impact of earthquake-dameged areas on the distribution and activities of giant pandas in the Qionglai Mountains was analyzed by comparing data from two giant panda surveys conducted in the Qionglai Mountains of Sichuan Province and combining with remote sensing(RS)data from relevant regions.The results indicated that there was only a small area of overlap between the earthquake-damaged areas and giant panda activity trace points.The main earthquake-damaged areas were distributed at elevations(3,500-4,100 m)higher than the primary elevation range of giant panda distribution(1,700-3,100 m).In the Wolong Nature Reserve,no major earthquake damage was observed in the central section east of Provincial Highway 303 with relatively more giant panda activities.Within the Caopo Nature Reserve,the earthquake-damaged areas were mostly concentrated in the northeastern corner and along the border with the Wolong Nature Reserve.However,no large-scale giant panda activity traces were detected in these areas during either of the two surveys.Overall,the range of giant panda activities showed no signs of decline.Therefore,the impact of earthquakes on giant panda activities remains limited.展开更多
BACKGROUND Choledochal cyst is a rare biliary tract disorder with five subtypes categorized based on the anatomical location of cystic dilatation.Type IV(which affects the intrahepatic and extrahepatic ducts)is the mo...BACKGROUND Choledochal cyst is a rare biliary tract disorder with five subtypes categorized based on the anatomical location of cystic dilatation.Type IV(which affects the intrahepatic and extrahepatic ducts)is the most common subtype in adults.Its clinical manifestations are diverse and the disease can potentially become malignant.Currently,the mainstay treatment is surgical excision which is used as a definitive treatment to prevent complications and avoid carcinogenesis.However,the surgical operation for giant choledochal cysts is technically challenging.CASE SUMMARY Here,we present a case of a giant choledochal cyst in an 18-year-old female.The diagnosis of patient was confirmed through magnetic resonance cholangiopancreatography.The patient developed acute cholangitis,and was treated with percutaneous transhepatic cholangial drainage to alleviate symptoms.The final treatment approach was cyst excision followed by Roux-en-Y hepaticojejunostomy,which successfully achieved excellent postoperative recovery.CONCLUSION Ultrasonography and magnetic resonance cholangiopancreatography can effectively diagnose choledochal cysts.Combined percutaneous transhepatic cholangial drainage surgery for giant choledochal cysts is safe and effective.展开更多
BACKGROUND Hepatic hemangioma represents the most common benign primary hepatic neo-plasm.Although most such tumors are small and asymptomatic,giant cavernous hemangioma(GCH)is frequently symptomatic,and needs interve...BACKGROUND Hepatic hemangioma represents the most common benign primary hepatic neo-plasm.Although most such tumors are small and asymptomatic,giant cavernous hemangioma(GCH)is frequently symptomatic,and needs intervention.More-over,diffuse hepatic hemangiomatosis(DHH)is not rare in the liver parenchyma adjacent to a GCH.The management strategy for hepatic hemangiomas can differ depending on the presence of associated hemangiomatosis and the amount and distribution of the residual hepatic parenchyma.CASE SUMMARY Herein,we report two patients with GCH coexistent with DHH successfully treated by laparoscopic microwave ablation.The two GCHs were ablated com-pletely and the ablated zone atrophied obviously in imaging follow-ups after ablation.Surprisingly,there was a trend toward gradual reduction and dimini-shment of DHH.CONCLUSION Thermal ablation treatment might be an effective and less invasive treatment for GCH coexistent with DHH around the hemangioma.展开更多
Giant panda writing is a classic form of thematic nature writing.Since the scientific discovery and the popularization of the giant panda by naturalists,this writing tradition has spanned nearly a century.Throughout t...Giant panda writing is a classic form of thematic nature writing.Since the scientific discovery and the popularization of the giant panda by naturalists,this writing tradition has spanned nearly a century.Throughout this process,Chinese giant panda writing has developed its own distinct characteristics.Western giant panda writing encompasses genres such as scientific essays,fieldwork notes,and documentary works.Within Chinese giant panda writing,reportage,popular science works,and comprehensive,systematic documentary works all have representative authors and texts.In recent years,IP-oriented giant panda books have shown notable performance.While Chinese giant panda writing exhibits diverse types and perspectives,its scientific rigor,informative value,and innovative expression still require enhancement.As a form of thematic nature writing,giant panda writing provides valuable insights for writings on other subjects.展开更多
BACKGROUND Leiomyomas or fibroids commonly originate from the uterus;extrauterine leiomyomas are rare and most often arise from the broad ligament.Diagnosing broad ligament leiomyomas becomes particularly challenging ...BACKGROUND Leiomyomas or fibroids commonly originate from the uterus;extrauterine leiomyomas are rare and most often arise from the broad ligament.Diagnosing broad ligament leiomyomas becomes particularly challenging when they undergo degenerative changes because their clinical and radiological features often mimic those of ovarian tumors.We report a rare case of a giant broad ligament fibroid with cystic degeneration,which was initially mistaken for an ovarian mass.CASE SUMMARY A 49-year-old woman presented with mild abdominal distension and pain as the only symptoms.Upon abdominal examination,a large mass measuring approximately 30 cm and extending from the pelvic cavity to just below the xiphoid process was identified.Both transvaginal ultrasound and contrast-enhanced computed tomography suggested an ovarian origin of the mass.However,laparotomy confirmed that the mass originated from the right broad ligament.The mass was separated from the uterus and bilateral ovaries,with no involvement of the uterus or ovaries.The mass was completely resected with respecting the patient’s desire to retain her uterus and adnexa.Postoperative histopathological examination confirmed leiomyoma with cystic degeneration.CONCLUSION Broad ligament myomas mimic ovarian tumors;accurate diagnosis and careful operation are critical to avoid complications and ensure safety.展开更多
With the commissioning of Phase$,the port of Kribi is emerging as an important maritime transport hub in Central Africa With a 715-metre quay and a draught of 16 metres,the Autonomous Port of Kribi(APK)stands as one o...With the commissioning of Phase$,the port of Kribi is emerging as an important maritime transport hub in Central Africa With a 715-metre quay and a draught of 16 metres,the Autonomous Port of Kribi(APK)stands as one of Africa’s most strategically significant deep-water ports.Situated on Cameroon’s Atlantic coast,it o!ers direct access to international shipping lanes and is designed to handle large-capacity vessels that many regional ports cannot accommodate.展开更多
Type 2 diabetes(T2D)presents a significant health challenge,underscoring the need for functional foods and nutraceutical hypoglycemic bioactive peptides for its prevention.This study investigates the potential of prot...Type 2 diabetes(T2D)presents a significant health challenge,underscoring the need for functional foods and nutraceutical hypoglycemic bioactive peptides for its prevention.This study investigates the potential of proteolytic hydrolysate from artificially cultivated Chinese giant salamander(CGS)meat,a rich protein source,as a preventive strategy for T2D.We produced a CGS meat hydrolysate(CGSh)and demonstrated its ability to inhibit the T2D drug target dipeptidyl peptidaseⅣ(DPP-Ⅳ)through in vitro assays.We identified 5 peptides(WRPPDH,WAPPSKD,IPDSPF,IPEMIF,and VPIAVPT)with high DPP-Ⅳinhibitory activity in CGSh,suggesting its potential antidiabetic effects.In vivo experiments showed that CGSh effectively reduced insulin resistance in mice induced with a high-fat diet,as evidenced by a slower increase in blood glucose levels and a decreased HOMA-IR index.16S rRNA sequencing analysis revealed that CGSh improved gut microbial homeostasis,promoting beneficial microorganisms and reducing harmful bacteria.Metabolomic analyses identified an increase in valeric acid levels and highlighted nine potential biomarker metabolites.By inhibiting metabolic pathways such as AGE-RAGE,CGSh might also prevent diabetic complications and reduce inflammation.These findings suggest that CGSh has a promising hypoglycemic effect,making it a potential functional food ingredient for T2D prevention and treatment.展开更多
BACKGROUND Giant coronary artery aneurysms(CAA),entailing thrombosis,myocardial infarction,and sudden death,are the most severe and life-threatening complications of Kawasaki disease(KD).Giant aneurysms rarely regress...BACKGROUND Giant coronary artery aneurysms(CAA),entailing thrombosis,myocardial infarction,and sudden death,are the most severe and life-threatening complications of Kawasaki disease(KD).Giant aneurysms rarely regress and can later transform into stenoses.Data on dynamic follow-up are scarce in the literature.AIM To evaluate clinical features and long-term outcomes of giant CAA in children with KD.METHODS A single-center retrospective study included data from patients with KD and giant CAA in the Irkutsk region(2012-2023).CAA criteria according to the American Heart Association guidelines of 2017 were used:(1)Dilated coronary artery with diameter Z-score>2 standard deviations(SD)but<2.5 SD;(2)Small CAA with Z-score>2.5 SD but<5 SD;(3)Medium CAA with Z-score>5 SD but<10 SD;and(4)Giant CAA with Z-score>10 SD or≥8 mm.RESULTS The mean age of children with coronary dilatation/aneurysms was 2.5 years,and the male-to-female ratio was 3:1.Patients with giant/medium CAA had symptoms of cerebral dysfunction more often compared with children with moderate(Z-score<5 SD but>2.0 SD)coronary dilatation(62.0%vs 21.0%,P=0.019).Major cardiovascular events(myocardial infarction,coronary artery bypass grafting,acute coronary syndrome,ischemic cardiomyopathy,left ventricular aneurysm,and giant extracardiac aneurysm)occurred in 55.5%of patients who had giant CAA.At follow-up the complete regression of giant/medium CAA was observed in 58.0%and partial regression in 42.0%after a mean of 2.3 and 5.5 years,respectively.All thrombi detected by echocardiography,CT,and angiography in giant/medium CAA disappeared between 1 year and 5 years(mean:15 months).All patients survived.CONCLUSION Risk factors for giant CAA were male sex,early age,and cerebral dysfunction.Complete regression of giant coronary aneurysms occurred in 58.0%of patients after follow-up of 2.3 years.展开更多
We study single photon scattering in a one-dimensional coupled resonator waveguide,which is dressed by a small and a giant artificial atom simultaneously.Here,we have set the small atom to be a neighbor to one leg of ...We study single photon scattering in a one-dimensional coupled resonator waveguide,which is dressed by a small and a giant artificial atom simultaneously.Here,we have set the small atom to be a neighbor to one leg of the giant atom,and the giant atom couples to the waveguide via two distant sites.When the small and giant atoms are both resonant with the bare resonator in the waveguide,we observe the perfect reflection of the resonant incident photon.On the other hand,when the small atom is detuned from the giant atom,the single photon reflection is characterized by a wide window and Fano line shape.We hope our work will pave the way for the potential application of small and giant atom hybrid systems in the study of photonic control in the lowdimensional waveguide structure.展开更多
The phase-controlled single-photon transport properties of a giant atom coupled to a one-dimensional waveguide are investigated.The coupling between the giant atom and the waveguide is modeled as a multi-point interac...The phase-controlled single-photon transport properties of a giant atom coupled to a one-dimensional waveguide are investigated.The coupling between the giant atom and the waveguide is modeled as a multi-point interaction.The coupling strengths between the giant atom and the waveguide are represented as complex numbers with associated phases.Analytical expressions for the scattering amplitudes are obtained using the real-space Hamiltonian method.The results show that the characteristics of the scattering spectra,including the positions of peaks(or dips)and the full width at half maximum,can be tuned by adjusting the phase difference between the coupling strengths.Further calculations reveal that the scattering spectra can be either super-broadened or sub-broadened.The conditions for achieving perfect nonreciprocal single-photon transport in the Markovian regime are also discussed.Moreover,we demonstrate the control of single-photon transport through phase differences in the non-Markovian regime.Our results may find applications in the design of quantum devices operating at the single-photon level,based on waveguide quantum electrodynamics.展开更多
The giant triton snail Charonia tritonis is a marine large carnivorous gastropoda inhabiting in the Indo-Pacific Ocean.Their splendid and highly organized Charonia tritonis shells are attractive;however few studies ha...The giant triton snail Charonia tritonis is a marine large carnivorous gastropoda inhabiting in the Indo-Pacific Ocean.Their splendid and highly organized Charonia tritonis shells are attractive;however few studies have been conducted on shell ultra-structure and pigmentation.The arrangements of crossed-lamellar structures were distinctive for the giant triton snail shell,showing three layers of mineral structures in the cross-section.The 1st-order and 2nd-order lamellae of the shell were around 10-20μm and the crystals in outer layers intersected at right angles in this species.They were identified as aragonite crystals by Raman scattering,and granular organic matrix were attached to the aragonite mineral phase closely.Furthermore,the dominant Raman spectra from polyene pigments in the shell were characterized at wavenumbers of 1123 cm^(-1)and 1504 cm^(-1),assigned to stretching vibrations of carbon-carbon single(C-C)and double(C=C)bonds,and the polyene chain was confirmed with 11-12 C-C bonds and 12-13 conju-gated C=C bonds.The research will lay a foundation for exploring the relationship between the calcareous shell and the formation of shell color in the giant triton snail.展开更多
This study examines the locomotor biomechanics of the giant panda(Ailuropoda melanoleuca),a species of profound ecological and evolutionary significance.Despite its characteristic slow movement and non-sprinting locom...This study examines the locomotor biomechanics of the giant panda(Ailuropoda melanoleuca),a species of profound ecological and evolutionary significance.Despite its characteristic slow movement and non-sprinting locomotion,the panda has endured for over 8 million years,offering a unique perspective on the evolution of mammalian locomotion.Through comprehensive gait analysis and ground reaction force measurements,we investigate the functional distinctions between the forelimbs and hind limbs,highlighting the biomechanical underpinnings of its plantigrade locomotion.Our findings reveal how the panda’s limb structure and movement patterns contribute to energy efficiency,particularly during slow locomotion.By comparing these results with those of other large mammals,such as grizzly bears(Ursus arcto),we explore the role of limb mechanics in energy conservation.Additionally,we assess the locomotor performance of pandas across different age groups,shedding light on the maturation of locomotor abilities and the potential adaptive significance of their slow,deliberate movement.This research offers novel insights into the biomechanics of panda locomotion and its evolutionary implications,furthering our understanding of the functional evolution of bear species and informing conservation strategies for this iconic species.展开更多
BACKGROUND Giant cell tumor of bone(GCTB)is a rare,locally aggressive neoplasm that should be treated surgically,whenever possible.This treatment approach may be linked with greater morbidity besides functional impair...BACKGROUND Giant cell tumor of bone(GCTB)is a rare,locally aggressive neoplasm that should be treated surgically,whenever possible.This treatment approach may be linked with greater morbidity besides functional impairment.Denosumab is a human monoclonal antibody.Its administration inhibits bone resorption and has become part of the therapeutic armamentarium against GCTB,as it allows local control with a view to downstaging for a more conservative surgical procedure.However,there is no consensus in the literature regarding the optimal denosumab regimen for GCTB.Therefore,a wide discussion of denosumab regimen is necessary.AIM To assess the effectiveness of various therapy protocols employing denosumab in individuals with GCTB.METHODS A broad and systematic literature search was carried out using the PRISMA guidelines.We analyzed studies that reported skeletally mature patients with GCTB regardless of sex or ethnicity treated with denosumab.Articles with fewer than five patients and in languages except Spanish,Portuguese and English were excluded.Statistical analysis with proportion meta-analysis was performed due to the dichotomous nature of the data.RESULTS 1005 articles were screened,of which 26 articles met the inclusion criteria and were selected,totaling 1742 patients,51.8%women and 48.2%men,with an average of 35 years of age.Treatment with denosumab was associated with high rates of clinical benefit(CB)and imaging response(IR),without changing local recurrence rates when compared to patients treated without denosumab,regardless of the therapeutic regimen adopted and the number of doses applied.The adverse events(AE)presented were mostly mild,with the exception of a malignant transformation to osteosarcoma.CONCLUSION Treatment of GCTB with denosumab is effective,showing high rates of CB and IR.The AE that occurred were mostly mild.We found no differences between the articles considering the researched outcomes regardless of the therapeutic regimen adopted.展开更多
Maintaining high piezoelectric response and piezoelectric temperature stability of lead-based piezoceramics is critical for applications under high-temperature environments.Unfortunately,the piezoelectric response of ...Maintaining high piezoelectric response and piezoelectric temperature stability of lead-based piezoceramics is critical for applications under high-temperature environments.Unfortunately,the piezoelectric response of lead-based piezoceramics shows strong temperature dependence.Herein,an innovative strategy was proposed to solve this problem.The method consisted of constructing“slush-like”polar states by introducing localized heterostructures in the tetragonal phase structure to lower the energy barriers.The presence of the tetragonal phase stabilized the domain structure,providing excellent temperature stability,while the localized heterostructures also flattened the free energy landscape and enhanced the piezo-electric response.The strategy was implemented by using 0.11Pb(In_(0.5)Nb_(0.5))O_(3)-0.89Pb(Hf_(0.47)Ti_(0.53))O_(3)(PIN-PHT)piezoceramics doped with heterovalent ion Nb^(5+)to form a“slush-like”polar state with strong in-teractions inside the ceramics.The piezoelectric response and relaxor behavior of the ceramics were then investigated using piezoelectric force microscopy to reveal the mapping relationship between the complex ferroelectric domain structure and both the piezoelectric response and temperature stability.At Nb5+doping amount of 0.8 mol%,the ceramics showed excellent comprehensive performances with d_(33)=764 pC/N,T_(c)=319.1℃,ε_(r)=3253.59,k_(p)=0.67,and tan δ=0.0122.At an external ambient temperature of 300℃,the d_(33) of PIN-PHT-0.8Nb^(5+) remained high at 734 pC/N,with piezoelectric performance retention of 96.1%,showing excellent temperature stability.Overall,a new path was proposed for developing Pb-based piezoceramics with both good piezoelectric response and high-temperature stability,promising to broaden the temperature range of high-temperature piezoceramics for various applications.展开更多
A research team led by Dr.GE Ziyi from the Ningbo Institute of Materials Technology and Engineering(NIMTE)of the Chinese Academy of Sciences has developed novel giant acceptors with an oxygenated linker,enabling the c...A research team led by Dr.GE Ziyi from the Ningbo Institute of Materials Technology and Engineering(NIMTE)of the Chinese Academy of Sciences has developed novel giant acceptors with an oxygenated linker,enabling the creation of highly efficient non-halogen-processed organic solar cells(OSCs),with a power conversion efficiency(PCE)up to 20.02%.展开更多
基金supported by the State Key Research and Development Program,Special Gravity Wave(Grant No.2023YFC2206003)the Gansu Provincial Science and Technology Program Funding(Grant No.24JRRA499)+1 种基金the Natural Science Foundation of Shandong Province(Grant No.ZR2024QB219)the Lanzhou City Science and Technology Program Project(Grant No.2025-2-47)。
文摘Giant magnetoimpedance(GMI)sensors are increasingly employed in modern magnetic sensing technologies.However,improving the GMI performance of magnetic cores remains challenging due to intrinsic limitations in material properties and structural stability.In this work,we explore the use of Joule heating to enhance the GMI response of Fe_(20)Ni_(80)/Cu composite wires.By applying a current of 1.8 A for 10 min,notable improvements in magnetic domain uniformity and a reduction in domain spacing are observed.Under these conditions,GMI ratios reach 1870% in the non-diagonal mode and1147%in the diagonal mode,respectively,highlighting their potential for applications in high-precision weak magnetic field sensing.
基金supported by grants from the Fundamental Research Funds for the Central Universities(No.2025ZFJH03)the Central Guidance Fund for Local Science and Technology Development(No.2024ZY01054)the CAMS Innovation Fund for Medical Sciences(No.2019-I2M-5-045).
文摘Background:Giant cell arteritis(GCA),the most common systemic vasculitis affecting elderly individuals,currently lacks specific therapies.This study aimed to systematically identify therapeutic targets for GCA through integration of large-scale multi-omics datasets.Methods:We constructed a multi-stage analytical framework encompassing 32 proteomic datasets(covering 2914 unique plasma proteins)and 6 transcriptomic datasets.Multi-omics integration strategies,including two-sample Mendelian randomization,colocalization analysis,and functional enrichment analysis,were employed to identify and validate causal relationships between candidate targets and GCA risk across 4 independent European-ancestry GCA cohorts.Single-cell RNA sequencing analysis of peripheral blood mononuclear cells from untreated GCA patients was performed to characterize hub gene-immune cell relationships.Results:We identified 43 plasma proteins causally associated with GCA[false discovery rate(FDR)<0.05],with 17 representing novel therapeutic targets.Through dual validation using proteome-wide association studies and transcriptome-wide association studies,we identified 13 high-confidence candidate targets with distinct tissue-specific expression patterns.Unc-51 like kinase 3(ULK3)emerged as the strongest protective factor(odds ratio=0.47,95%confidence interval:0.37–0.71)through autophagy regulation,while SLAMF7 represents an immediate drug repositioning opportunity as the target of food and drug administration-approved elotuzumab.Five targets have existing approved drugs(SLAMF7,ICAM1,IL18,IL6ST,CTSS).Single-cell analysis revealed profound disruption of hub gene-immune cell relationships in untreated GCA patients,with cell-type-specific alterations in inflammatory gene expression,and TYMP as the most critical hub gene.Conclusions:This study provides a clinically-actionable atlas of 43 potential therapeutic targets in GCA,identifying novel mechanisms including autophagy modulation and metabolic reprogramming,with immediate drug repositioning opportunities and precision medicine strategies based on tissue-specific and cell-type-specific expression patterns.These findings require experimental validation before clinical translation.
文摘1.Introduction As the planets closest to the outer edge of the solar system,Uranus and Neptune,namely that of ice giants,retained a significant amount of gas from the early stages of the solar system's formation.This gas contains the physical conditions of the protostellar cloud and position information about planet formation,making ice giants important prototypes for studying both the solar system and exoplanets.
文摘Bcakground: Pancreatic pseudocyst (PPC) is a common complication arising from acute or chronic pancreatitis, trauma, or pancreatic duct obstruction. When acute fluid collection persists for 4 - 6 weeks and is encapsulated by a fibrous wall, it is classified as a pancreatic pseudocyst. While PPC is generally asymptomatic in many patients, it can manifest with persistent abdominal pain, dyspepsia, intra-cystic infection, and potentially lead to gastrointestinal obstruction in some cases. Although smaller PPCs may resolve spontaneously, larger PPCs tend to be refractory to absorption and often necessitate surgical intervention to prevent complications such as intracystic hemorrhage. Objective: To explore the efficacy of percutaneous catheterization with negative pressure in the treatment of large pancreatic pseudocysts. Methods: The cases of large pancreatic pseudocysts treated in our hospital from 2004 to 2022 were retrospectively collected, and the general condition, operation time, drainage time, feeding time, postoperative complications, hospital stay, cost and follow-up of the patients were analyzed. Results: A total of 132 patients with large pancreatic pseudocysts were collected. The average operation time was 32.4 ± 2.1 min;The retention time of the drainage tube was 30 ± 1.8 days in the percutaneous negative pressure drainage group;The postoperative feeding time was no fasting after local anesthesia drainage;Postoperative complications (bleeding, infection, pancreatic leakage, recurrence, anastomotic leakage, etc.): Two of the 132 patients had recurrent cysts, which were cured by re-puncture and negative pressure drainage. The length of hospital stay was 6 ± 1.1 days;The cost was 11,200 ± 1300 yuan;Follow-up: The follow-up time ranged from 1 to 3 years, and the patients had no discomfort. Conclusion: Percutaneous catheterization and negative pressure drainage can effectively treat large pancreatic pseudocysts. Compared with other treatment methods, it is simple and effective, the postoperative recovery of patients is faster, the physical damage is less, the hospital stay is shorter, and the cost is lower.
文摘BACKGROUND Retroperitoneal liposarcoma(RPLS)is a rare malignant tumor initiated in adipocytes.It is discovered only when the tumor is large because of its deep anatomical location and insidious onset.Giant RPLS with a diameter exceeding 30 cm is extremely rare.Its diagnosis and treatment present extremely great challenges.CASE SUMMARY The patient,a 62-year-old woman,presented to the hospital complaining of abdominal distension for more than six months.Imaging examination revealed a large retroperitoneal mass.Finally,the patient was diagnosed with giant RPLS.The tumor occupied the entire abdominal cavity,severely compressed the abdominal organs,and adhered tightly to the bilateral ureters.After careful preoperative preparation(including three-dimensional visualization and bilateral ureteral stent implantation),we performed resection of the large retroperitoneal mass.The tumor was completely removed and consisted of multiple masses,with a total weight of 17 kg and the largest mass size of 35 cm×28 cm×14 cm.Postoperative pathological results revealed that the mass was a well-differentiated liposarcoma.The patient recovered well after surgery,and there was no sign of recurrence after 2 months of follow-up.CONCLUSION Surgical resection is the only radical treatment for giant RPLS.Preoperative preparation is essential,and three-dimensional visualization reconstruction is helpful for the formulation of surgical plans.Postoperative radiotherapy and neoadjuvant therapy can be reasonably selected,but whether they can reduce the recurrence rate is still controversial.
文摘As an endemic and critically-endangered wildlife species in China,the giant panda(Ailuropoda melanoleuca)has attracted widespread attention from all sectors of society regarding its survival status.In this study,the impact of earthquake-dameged areas on the distribution and activities of giant pandas in the Qionglai Mountains was analyzed by comparing data from two giant panda surveys conducted in the Qionglai Mountains of Sichuan Province and combining with remote sensing(RS)data from relevant regions.The results indicated that there was only a small area of overlap between the earthquake-damaged areas and giant panda activity trace points.The main earthquake-damaged areas were distributed at elevations(3,500-4,100 m)higher than the primary elevation range of giant panda distribution(1,700-3,100 m).In the Wolong Nature Reserve,no major earthquake damage was observed in the central section east of Provincial Highway 303 with relatively more giant panda activities.Within the Caopo Nature Reserve,the earthquake-damaged areas were mostly concentrated in the northeastern corner and along the border with the Wolong Nature Reserve.However,no large-scale giant panda activity traces were detected in these areas during either of the two surveys.Overall,the range of giant panda activities showed no signs of decline.Therefore,the impact of earthquakes on giant panda activities remains limited.
基金Supported by Cuiying Scientific and Technological Innovation Program of Lanzhou University Second Hospital,No.CY2024-MS-B04Gansu Provincial Natural Science Foundation Project,No.24JRRA331the Traditional Chinese Medicine Research Project of Gansu Province,No.GZKZ-2024-26.
文摘BACKGROUND Choledochal cyst is a rare biliary tract disorder with five subtypes categorized based on the anatomical location of cystic dilatation.Type IV(which affects the intrahepatic and extrahepatic ducts)is the most common subtype in adults.Its clinical manifestations are diverse and the disease can potentially become malignant.Currently,the mainstay treatment is surgical excision which is used as a definitive treatment to prevent complications and avoid carcinogenesis.However,the surgical operation for giant choledochal cysts is technically challenging.CASE SUMMARY Here,we present a case of a giant choledochal cyst in an 18-year-old female.The diagnosis of patient was confirmed through magnetic resonance cholangiopancreatography.The patient developed acute cholangitis,and was treated with percutaneous transhepatic cholangial drainage to alleviate symptoms.The final treatment approach was cyst excision followed by Roux-en-Y hepaticojejunostomy,which successfully achieved excellent postoperative recovery.CONCLUSION Ultrasonography and magnetic resonance cholangiopancreatography can effectively diagnose choledochal cysts.Combined percutaneous transhepatic cholangial drainage surgery for giant choledochal cysts is safe and effective.
文摘BACKGROUND Hepatic hemangioma represents the most common benign primary hepatic neo-plasm.Although most such tumors are small and asymptomatic,giant cavernous hemangioma(GCH)is frequently symptomatic,and needs intervention.More-over,diffuse hepatic hemangiomatosis(DHH)is not rare in the liver parenchyma adjacent to a GCH.The management strategy for hepatic hemangiomas can differ depending on the presence of associated hemangiomatosis and the amount and distribution of the residual hepatic parenchyma.CASE SUMMARY Herein,we report two patients with GCH coexistent with DHH successfully treated by laparoscopic microwave ablation.The two GCHs were ablated com-pletely and the ablated zone atrophied obviously in imaging follow-ups after ablation.Surprisingly,there was a trend toward gradual reduction and dimini-shment of DHH.CONCLUSION Thermal ablation treatment might be an effective and less invasive treatment for GCH coexistent with DHH around the hemangioma.
文摘Giant panda writing is a classic form of thematic nature writing.Since the scientific discovery and the popularization of the giant panda by naturalists,this writing tradition has spanned nearly a century.Throughout this process,Chinese giant panda writing has developed its own distinct characteristics.Western giant panda writing encompasses genres such as scientific essays,fieldwork notes,and documentary works.Within Chinese giant panda writing,reportage,popular science works,and comprehensive,systematic documentary works all have representative authors and texts.In recent years,IP-oriented giant panda books have shown notable performance.While Chinese giant panda writing exhibits diverse types and perspectives,its scientific rigor,informative value,and innovative expression still require enhancement.As a form of thematic nature writing,giant panda writing provides valuable insights for writings on other subjects.
文摘BACKGROUND Leiomyomas or fibroids commonly originate from the uterus;extrauterine leiomyomas are rare and most often arise from the broad ligament.Diagnosing broad ligament leiomyomas becomes particularly challenging when they undergo degenerative changes because their clinical and radiological features often mimic those of ovarian tumors.We report a rare case of a giant broad ligament fibroid with cystic degeneration,which was initially mistaken for an ovarian mass.CASE SUMMARY A 49-year-old woman presented with mild abdominal distension and pain as the only symptoms.Upon abdominal examination,a large mass measuring approximately 30 cm and extending from the pelvic cavity to just below the xiphoid process was identified.Both transvaginal ultrasound and contrast-enhanced computed tomography suggested an ovarian origin of the mass.However,laparotomy confirmed that the mass originated from the right broad ligament.The mass was separated from the uterus and bilateral ovaries,with no involvement of the uterus or ovaries.The mass was completely resected with respecting the patient’s desire to retain her uterus and adnexa.Postoperative histopathological examination confirmed leiomyoma with cystic degeneration.CONCLUSION Broad ligament myomas mimic ovarian tumors;accurate diagnosis and careful operation are critical to avoid complications and ensure safety.
文摘With the commissioning of Phase$,the port of Kribi is emerging as an important maritime transport hub in Central Africa With a 715-metre quay and a draught of 16 metres,the Autonomous Port of Kribi(APK)stands as one of Africa’s most strategically significant deep-water ports.Situated on Cameroon’s Atlantic coast,it o!ers direct access to international shipping lanes and is designed to handle large-capacity vessels that many regional ports cannot accommodate.
基金funded by the Shenzhen Agricultural Development Special Fund(Fishery)Agricultural High-tech Project([2021]735)SAMR technical guarantee project(2023YJ22 and 2023YJ37)。
文摘Type 2 diabetes(T2D)presents a significant health challenge,underscoring the need for functional foods and nutraceutical hypoglycemic bioactive peptides for its prevention.This study investigates the potential of proteolytic hydrolysate from artificially cultivated Chinese giant salamander(CGS)meat,a rich protein source,as a preventive strategy for T2D.We produced a CGS meat hydrolysate(CGSh)and demonstrated its ability to inhibit the T2D drug target dipeptidyl peptidaseⅣ(DPP-Ⅳ)through in vitro assays.We identified 5 peptides(WRPPDH,WAPPSKD,IPDSPF,IPEMIF,and VPIAVPT)with high DPP-Ⅳinhibitory activity in CGSh,suggesting its potential antidiabetic effects.In vivo experiments showed that CGSh effectively reduced insulin resistance in mice induced with a high-fat diet,as evidenced by a slower increase in blood glucose levels and a decreased HOMA-IR index.16S rRNA sequencing analysis revealed that CGSh improved gut microbial homeostasis,promoting beneficial microorganisms and reducing harmful bacteria.Metabolomic analyses identified an increase in valeric acid levels and highlighted nine potential biomarker metabolites.By inhibiting metabolic pathways such as AGE-RAGE,CGSh might also prevent diabetic complications and reduce inflammation.These findings suggest that CGSh has a promising hypoglycemic effect,making it a potential functional food ingredient for T2D prevention and treatment.
文摘BACKGROUND Giant coronary artery aneurysms(CAA),entailing thrombosis,myocardial infarction,and sudden death,are the most severe and life-threatening complications of Kawasaki disease(KD).Giant aneurysms rarely regress and can later transform into stenoses.Data on dynamic follow-up are scarce in the literature.AIM To evaluate clinical features and long-term outcomes of giant CAA in children with KD.METHODS A single-center retrospective study included data from patients with KD and giant CAA in the Irkutsk region(2012-2023).CAA criteria according to the American Heart Association guidelines of 2017 were used:(1)Dilated coronary artery with diameter Z-score>2 standard deviations(SD)but<2.5 SD;(2)Small CAA with Z-score>2.5 SD but<5 SD;(3)Medium CAA with Z-score>5 SD but<10 SD;and(4)Giant CAA with Z-score>10 SD or≥8 mm.RESULTS The mean age of children with coronary dilatation/aneurysms was 2.5 years,and the male-to-female ratio was 3:1.Patients with giant/medium CAA had symptoms of cerebral dysfunction more often compared with children with moderate(Z-score<5 SD but>2.0 SD)coronary dilatation(62.0%vs 21.0%,P=0.019).Major cardiovascular events(myocardial infarction,coronary artery bypass grafting,acute coronary syndrome,ischemic cardiomyopathy,left ventricular aneurysm,and giant extracardiac aneurysm)occurred in 55.5%of patients who had giant CAA.At follow-up the complete regression of giant/medium CAA was observed in 58.0%and partial regression in 42.0%after a mean of 2.3 and 5.5 years,respectively.All thrombi detected by echocardiography,CT,and angiography in giant/medium CAA disappeared between 1 year and 5 years(mean:15 months).All patients survived.CONCLUSION Risk factors for giant CAA were male sex,early age,and cerebral dysfunction.Complete regression of giant coronary aneurysms occurred in 58.0%of patients after follow-up of 2.3 years.
基金supported by funding from Jilin Province(Grant No.20230101357JC)the National Science Foundation of China(Grant Nos.12105026 and No.12375010)the Educational Commission of Jilin Province of China(Grant No.JJKH20230663KJ)。
文摘We study single photon scattering in a one-dimensional coupled resonator waveguide,which is dressed by a small and a giant artificial atom simultaneously.Here,we have set the small atom to be a neighbor to one leg of the giant atom,and the giant atom couples to the waveguide via two distant sites.When the small and giant atoms are both resonant with the bare resonator in the waveguide,we observe the perfect reflection of the resonant incident photon.On the other hand,when the small atom is detuned from the giant atom,the single photon reflection is characterized by a wide window and Fano line shape.We hope our work will pave the way for the potential application of small and giant atom hybrid systems in the study of photonic control in the lowdimensional waveguide structure.
基金supported by the National Natural Science Foundation of China(Grant Nos.12475010 and 119075023)the Major Project of the Natural Science Foundation of Anhui Provincial Department of Education(Grant No.2022AH040053)the Key Natural Scientific Research Projects of Universities in Anhui Province(Grant Nos.2023AH051078 and 2023AH051125)。
文摘The phase-controlled single-photon transport properties of a giant atom coupled to a one-dimensional waveguide are investigated.The coupling between the giant atom and the waveguide is modeled as a multi-point interaction.The coupling strengths between the giant atom and the waveguide are represented as complex numbers with associated phases.Analytical expressions for the scattering amplitudes are obtained using the real-space Hamiltonian method.The results show that the characteristics of the scattering spectra,including the positions of peaks(or dips)and the full width at half maximum,can be tuned by adjusting the phase difference between the coupling strengths.Further calculations reveal that the scattering spectra can be either super-broadened or sub-broadened.The conditions for achieving perfect nonreciprocal single-photon transport in the Markovian regime are also discussed.Moreover,we demonstrate the control of single-photon transport through phase differences in the non-Markovian regime.Our results may find applications in the design of quantum devices operating at the single-photon level,based on waveguide quantum electrodynamics.
基金funded by the Guangzhou Sci-ence and Technology Project(No.201803020017).
文摘The giant triton snail Charonia tritonis is a marine large carnivorous gastropoda inhabiting in the Indo-Pacific Ocean.Their splendid and highly organized Charonia tritonis shells are attractive;however few studies have been conducted on shell ultra-structure and pigmentation.The arrangements of crossed-lamellar structures were distinctive for the giant triton snail shell,showing three layers of mineral structures in the cross-section.The 1st-order and 2nd-order lamellae of the shell were around 10-20μm and the crystals in outer layers intersected at right angles in this species.They were identified as aragonite crystals by Raman scattering,and granular organic matrix were attached to the aragonite mineral phase closely.Furthermore,the dominant Raman spectra from polyene pigments in the shell were characterized at wavenumbers of 1123 cm^(-1)and 1504 cm^(-1),assigned to stretching vibrations of carbon-carbon single(C-C)and double(C=C)bonds,and the polyene chain was confirmed with 11-12 C-C bonds and 12-13 conju-gated C=C bonds.The research will lay a foundation for exploring the relationship between the calcareous shell and the formation of shell color in the giant triton snail.
基金supported by the National Natural Science Foundation of China(grant numbers 52405317 and 52075248)the Natural Science Foundation of Jiangsu Province(BK20241407)+3 种基金the Excellence Postdoctoral Project of Jiangsu Province(2024ZB421)the Fundamental Research Funds for the Central Universities(NP2024302)the National Key Laboratory of Aircraft Configuration Design(No.ZZKY-202507)the Jiangsu Key Laboratory of Advanced Robotics Technology(No.KJS2449).
文摘This study examines the locomotor biomechanics of the giant panda(Ailuropoda melanoleuca),a species of profound ecological and evolutionary significance.Despite its characteristic slow movement and non-sprinting locomotion,the panda has endured for over 8 million years,offering a unique perspective on the evolution of mammalian locomotion.Through comprehensive gait analysis and ground reaction force measurements,we investigate the functional distinctions between the forelimbs and hind limbs,highlighting the biomechanical underpinnings of its plantigrade locomotion.Our findings reveal how the panda’s limb structure and movement patterns contribute to energy efficiency,particularly during slow locomotion.By comparing these results with those of other large mammals,such as grizzly bears(Ursus arcto),we explore the role of limb mechanics in energy conservation.Additionally,we assess the locomotor performance of pandas across different age groups,shedding light on the maturation of locomotor abilities and the potential adaptive significance of their slow,deliberate movement.This research offers novel insights into the biomechanics of panda locomotion and its evolutionary implications,furthering our understanding of the functional evolution of bear species and informing conservation strategies for this iconic species.
文摘BACKGROUND Giant cell tumor of bone(GCTB)is a rare,locally aggressive neoplasm that should be treated surgically,whenever possible.This treatment approach may be linked with greater morbidity besides functional impairment.Denosumab is a human monoclonal antibody.Its administration inhibits bone resorption and has become part of the therapeutic armamentarium against GCTB,as it allows local control with a view to downstaging for a more conservative surgical procedure.However,there is no consensus in the literature regarding the optimal denosumab regimen for GCTB.Therefore,a wide discussion of denosumab regimen is necessary.AIM To assess the effectiveness of various therapy protocols employing denosumab in individuals with GCTB.METHODS A broad and systematic literature search was carried out using the PRISMA guidelines.We analyzed studies that reported skeletally mature patients with GCTB regardless of sex or ethnicity treated with denosumab.Articles with fewer than five patients and in languages except Spanish,Portuguese and English were excluded.Statistical analysis with proportion meta-analysis was performed due to the dichotomous nature of the data.RESULTS 1005 articles were screened,of which 26 articles met the inclusion criteria and were selected,totaling 1742 patients,51.8%women and 48.2%men,with an average of 35 years of age.Treatment with denosumab was associated with high rates of clinical benefit(CB)and imaging response(IR),without changing local recurrence rates when compared to patients treated without denosumab,regardless of the therapeutic regimen adopted and the number of doses applied.The adverse events(AE)presented were mostly mild,with the exception of a malignant transformation to osteosarcoma.CONCLUSION Treatment of GCTB with denosumab is effective,showing high rates of CB and IR.The AE that occurred were mostly mild.We found no differences between the articles considering the researched outcomes regardless of the therapeutic regimen adopted.
基金support of the National Ceramic Industry Design Institute of China(No.NI-CID2022Z02)the Instrumental Analysis Center of Xidian University for providing test equipment,the Shaanxi Key Laboratory of High-Orbits-Electron Materials and Protection Technology for Aerospace,the Aeronautical Science Foundation of China(No.2022Z033081001)+1 种基金the Xidian University Specially Funded Project for Interdisciplinary Exploration(No.TZJH2024055)the financial supports of the Key Research and Development Program of Shaanxi(No.2022GY-184).
文摘Maintaining high piezoelectric response and piezoelectric temperature stability of lead-based piezoceramics is critical for applications under high-temperature environments.Unfortunately,the piezoelectric response of lead-based piezoceramics shows strong temperature dependence.Herein,an innovative strategy was proposed to solve this problem.The method consisted of constructing“slush-like”polar states by introducing localized heterostructures in the tetragonal phase structure to lower the energy barriers.The presence of the tetragonal phase stabilized the domain structure,providing excellent temperature stability,while the localized heterostructures also flattened the free energy landscape and enhanced the piezo-electric response.The strategy was implemented by using 0.11Pb(In_(0.5)Nb_(0.5))O_(3)-0.89Pb(Hf_(0.47)Ti_(0.53))O_(3)(PIN-PHT)piezoceramics doped with heterovalent ion Nb^(5+)to form a“slush-like”polar state with strong in-teractions inside the ceramics.The piezoelectric response and relaxor behavior of the ceramics were then investigated using piezoelectric force microscopy to reveal the mapping relationship between the complex ferroelectric domain structure and both the piezoelectric response and temperature stability.At Nb5+doping amount of 0.8 mol%,the ceramics showed excellent comprehensive performances with d_(33)=764 pC/N,T_(c)=319.1℃,ε_(r)=3253.59,k_(p)=0.67,and tan δ=0.0122.At an external ambient temperature of 300℃,the d_(33) of PIN-PHT-0.8Nb^(5+) remained high at 734 pC/N,with piezoelectric performance retention of 96.1%,showing excellent temperature stability.Overall,a new path was proposed for developing Pb-based piezoceramics with both good piezoelectric response and high-temperature stability,promising to broaden the temperature range of high-temperature piezoceramics for various applications.
文摘A research team led by Dr.GE Ziyi from the Ningbo Institute of Materials Technology and Engineering(NIMTE)of the Chinese Academy of Sciences has developed novel giant acceptors with an oxygenated linker,enabling the creation of highly efficient non-halogen-processed organic solar cells(OSCs),with a power conversion efficiency(PCE)up to 20.02%.
