Objective To observe the clinical therapeutic effect on insomnia treated with acupuncture at back-shu points. Methods Sixty-four cases of insomnia were selected and divided randomly into a back-shu points group （grou...Objective To observe the clinical therapeutic effect on insomnia treated with acupuncture at back-shu points. Methods Sixty-four cases of insomnia were selected and divided randomly into a back-shu points group （group A） and a conventional acupoints group （group B） by a computer generated allocation list, 32 cases in each one. In the trial group, acupuncture was applied at xinshu （心俞 15）, Ganshu （刊俞 18）, Pishu （脾俞 BL 20） and Geshu （膈俞 BL 17）. In the control group, acupuncture was applied conventionally to Neiguan （内关 PC 6）, Shenmen （神门 HT 7）, Sanyinjiao （三阴交 SP 6）, Baihui （百会 GV 20） and Sishencong （四神聪 EX-HN 2）. Ten treatments made a session. The efficacy was analyzed statistically after 3 sessions of treatment. Results There were significant differences between the two groups in the relief of sleep disorders after the treatment （P〈0.O2）. The improvement in sleep efficiency was different significantly （P〈0.05）. The difference in sleep difficulty was significant in Chinese medicine （TCM） symptom score （P〈0.05）. Conclusion The clinical efficacy is achieved by either acupuncture at back-shu points or by acupuncture at conventional acupoints. The improvements of sleep efficiency and sleep disorder scores in PSO.I, and sleep difficulty in TCM as well as the long-term efficacy are superior in group A as compared with those in group B.展开更多
目的:观察四花穴麦粒灸结合疏肝泻火汤治疗气郁化火型中风后抑郁的临床疗效。方法:将96例中风后抑郁患者按照随机数字表法分为对照组和观察组,每组各48例。对照组给予氟西汀治疗,观察组在对照组治疗的基础上给予四花穴麦粒灸结合疏肝泻...目的:观察四花穴麦粒灸结合疏肝泻火汤治疗气郁化火型中风后抑郁的临床疗效。方法:将96例中风后抑郁患者按照随机数字表法分为对照组和观察组,每组各48例。对照组给予氟西汀治疗,观察组在对照组治疗的基础上给予四花穴麦粒灸结合疏肝泻火汤治疗。比较两组患者治疗前后中医证候积分、神经功能[血清5-羟色胺(5-hydroxy tryptamin,5-HT)、S100-β、美国国立卫生院神经功能缺损评分(national institutes of health neurological deficit score,NIH-SS)]、抑郁及日常生活状态[汉密尔顿焦虑量表(hamilton depression scale,HAMD)评分、日常生活活动能力量表(activity of daily living,ADL)评分]及不良反应发生情况。结果:两组患者治疗后口角歪斜、胸胁胀满、头晕耳鸣及舌红苔黄评分低于本组治疗前,且治疗后观察组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后5-HT高于本组治疗前,S100-β、NIHSS评分低于本组治疗前,观察组治疗后5-HT高于对照组,S100-β、NIHSS评分低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后ADL评分高于本组治疗前,HAMD评分低于本组治疗前,观察组治疗后ADL评分高于对照组,HAMD评分低于对照组,差异具有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:四花穴麦粒灸结合疏肝泻火汤治疗气郁化火型中风后抑郁,可改善患者神经功能、抑郁状态,提高日常生活能力。展开更多
Ojective:To explored the effectiveness and safety of acupuncture at back-shu points of five zang and Geshu(BL 17)for bipolar depression,and its mechanism from the aspect of the anti-inflammatory response.Background:Bi...Ojective:To explored the effectiveness and safety of acupuncture at back-shu points of five zang and Geshu(BL 17)for bipolar depression,and its mechanism from the aspect of the anti-inflammatory response.Background:Bipolar disorder is a very common,often misdiagnosed mental disorder strongly associated with comorbidity,disability,and premature mortality.Bipolar depression(ie,depressive episode in bipolar disorder)is poorly responsive to available treatments.Acupuncture at back-shu points of five zang and Geshu(BL 17),a prescription from Dr.Leting Wang,is a popular therapy for depression in China.Its effectiveness and safety for bipolar depression are yet to be verified by clinical studies.Methods:The study is a single-center,prospective,randomized controlled trial involving 72 patients diagnosed with bipolar depression.Participants will be randomized either to the study group or the control group in a 1:1 ratio.All participants will receive mood stabilizer therapy.In addition,the study group will receive acupuncture therapy at back-shu points of five zang and Geshu(BL 17),three times per week.The control group will orally take the antidepressant bupropion.Observation and intervention will last for 8 consecutive weeks.Outcome measurements include Hamilton Depression Rating Scale-17,Hamilton Anxiety Rating Scale,Clinical Global Impression Scale,Young Manic Rating Scale,Treatment Emergent Symptom Scale,serum levels of anti-inflammatory cytokines[interleukin-4(IL-40),IL-10,and transforming growth factor–β,pro-inflammatory cytokines(IL-1β,IL-6,and tumor necrosis factor–α),brain-derived neurotrophic factor,and C-reactive protein.Assessments will be conducted at baseline,first,second,fourth,and eighth weeks after randomization.Safety assessments will be performed throughout the study.Discussion:The results of this study are expected to verify the effectiveness and safety of acupuncture at back-shu points of five zang and Geshu(BL 17)for bipolar depression,and explore its therapeutic mechanisms from the point of anti-inflammation.展开更多
Objective： To observe the clinical effect of liver-regulating and blood-tonifying acupuncture in the treatment of cervical spondylosis of vertebral artery type. Methods： A total of 60 cases meeting the inclusion cri...Objective： To observe the clinical effect of liver-regulating and blood-tonifying acupuncture in the treatment of cervical spondylosis of vertebral artery type. Methods： A total of 60 cases meeting the inclusion criteria were randomized into an observation group and a control group, 30 cases in each group. Cases in the observation group received liver-regulating and blood-tonifying acupuncture, in which Jiaji （EX-B 2） points of C3_C7, Ganshu （BL 18） and Geshu （BL 17） were used; cases in the control group received routine acupuncture treatment in which jiaji （EX-B2） points of C3.C7 were used. Both groups received 5 times of treatment in a week with a 2-day rest, symptoms evaluation was done after 4 weeks of treatment, and then therapeutical effect was evaluated. Results： The total effective rate was 90.0% in the observation group, 73.3% in the control group, and inter-group comparison showed a statistical significance （P〈0.05）. After treatment, the symptoms and signs scores in both groups all substantially dropped, showing statistical significances （both P〈0.05）; inter-group comparison showed that the improvements in subscales of dizziness, pressing pain along vertebrae and revolve-cervix test in the observation group were superior than those in the control group, showing statistical significances （all P〈0.05）, while the inter-group comparisons of subscales of headache and vomiting and nause didn＇t show any statistical significances after treatment （both P〉0.05）. Conclusion： Liver-regulating and blood-tonifying acupuncture is effective in treating cervical spondylosis of vertebral artery type, and it can significantly improve patients＇ symptoms and signs.展开更多
Objective:To observe and evaluate the clinical efficacy and safety of using pediatric Tuina(Chinese therapeutic massage),Tui-Pushing chest-back manipulation,in treating children with cough variant asthma(CVA).Methods:...Objective:To observe and evaluate the clinical efficacy and safety of using pediatric Tuina(Chinese therapeutic massage),Tui-Pushing chest-back manipulation,in treating children with cough variant asthma(CVA).Methods:Seventy-two kids with CVA were divided into two groups using the random number table method,with 36 cases in each group.The control group received the conventional Tuina treatment,and the observation group received additional Tui-Pushing chest-back manipulation.The clinical efficacy and adverse reactions were observed and recorded for the two groups.Results:After three treatment courses,compared with the control group,the observation group showed advantages in the total effective rate,reducing the number and intensity of cough and improving the nature of cough(P<0.05).However,at the one-month follow-up,there were no significant differences between the two groups in these parameters(P>0.05).Regarding the adverse reaction rate,there was no significant between-group difference(P>0.05).Conclusion:It is effective and safe to use pediatric Tuina,Tui-Pushing chest-back manipulation,plus the conventional treatment protocol to treat CVA in children.展开更多
Twenty-four cases of hiccup were treated by needle-embedding therapy at Geshu(BL 17),Ear Centre(MA-H 1)and Stomach(MA-IC).Results showed that hiccup disappeared in 21 cases,relieved in 1 case and changed little in 2 c...Twenty-four cases of hiccup were treated by needle-embedding therapy at Geshu(BL 17),Ear Centre(MA-H 1)and Stomach(MA-IC).Results showed that hiccup disappeared in 21 cases,relieved in 1 case and changed little in 2 cases;that in some cases hiccup disappeared instantly after embedding needle.Itìs indicated that needle-embedding therapy is a quick and easy way to treat hiccup,with lasting effects.展开更多
Objective. To investigate the effect of acupuncture or moxibustion at acupoint Geshu （BL 17） on raising leukocyte and promoting marrow proliferation. Methods.. Wister rats were selected to establish the leukopenia a...Objective. To investigate the effect of acupuncture or moxibustion at acupoint Geshu （BL 17） on raising leukocyte and promoting marrow proliferation. Methods.. Wister rats were selected to establish the leukopenia and immuno-suppression model by intraperitoneal injection of cytoxan （CTX）. After they were grouped and treated, leukocyte and marrow karyocyte were counted in different phases to evaluate the effect of acupuncture or moxibustion at acupoint Geshu （BL 17） on raising leukocyte and promoting marrow hematopoiesis. Results. Acupuncture or moxibustion at acupoint Geshu （BL 17） and routine western medicine could all significantly raise leukocyte and increase marrow karyocyte. The curative effect was better in moxibustion group than in acupuncture group and in routine western medicine group （P〈 0.05）. Conclusion. Moxibustion at acupoint Geshu （BL 17） can markedly raise peripheral blood leukocyte and marrow karyocyte of the leucopenia model in rats.展开更多
基金Supported by National Natural Science Foundation:No.81173335
文摘Objective To observe the clinical therapeutic effect on insomnia treated with acupuncture at back-shu points. Methods Sixty-four cases of insomnia were selected and divided randomly into a back-shu points group （group A） and a conventional acupoints group （group B） by a computer generated allocation list, 32 cases in each one. In the trial group, acupuncture was applied at xinshu （心俞 15）, Ganshu （刊俞 18）, Pishu （脾俞 BL 20） and Geshu （膈俞 BL 17）. In the control group, acupuncture was applied conventionally to Neiguan （内关 PC 6）, Shenmen （神门 HT 7）, Sanyinjiao （三阴交 SP 6）, Baihui （百会 GV 20） and Sishencong （四神聪 EX-HN 2）. Ten treatments made a session. The efficacy was analyzed statistically after 3 sessions of treatment. Results There were significant differences between the two groups in the relief of sleep disorders after the treatment （P〈0.O2）. The improvement in sleep efficiency was different significantly （P〈0.05）. The difference in sleep difficulty was significant in Chinese medicine （TCM） symptom score （P〈0.05）. Conclusion The clinical efficacy is achieved by either acupuncture at back-shu points or by acupuncture at conventional acupoints. The improvements of sleep efficiency and sleep disorder scores in PSO.I, and sleep difficulty in TCM as well as the long-term efficacy are superior in group A as compared with those in group B.
文摘目的:观察四花穴麦粒灸结合疏肝泻火汤治疗气郁化火型中风后抑郁的临床疗效。方法:将96例中风后抑郁患者按照随机数字表法分为对照组和观察组,每组各48例。对照组给予氟西汀治疗,观察组在对照组治疗的基础上给予四花穴麦粒灸结合疏肝泻火汤治疗。比较两组患者治疗前后中医证候积分、神经功能[血清5-羟色胺(5-hydroxy tryptamin,5-HT)、S100-β、美国国立卫生院神经功能缺损评分(national institutes of health neurological deficit score,NIH-SS)]、抑郁及日常生活状态[汉密尔顿焦虑量表(hamilton depression scale,HAMD)评分、日常生活活动能力量表(activity of daily living,ADL)评分]及不良反应发生情况。结果:两组患者治疗后口角歪斜、胸胁胀满、头晕耳鸣及舌红苔黄评分低于本组治疗前,且治疗后观察组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后5-HT高于本组治疗前,S100-β、NIHSS评分低于本组治疗前,观察组治疗后5-HT高于对照组,S100-β、NIHSS评分低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后ADL评分高于本组治疗前,HAMD评分低于本组治疗前,观察组治疗后ADL评分高于对照组,HAMD评分低于对照组,差异具有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:四花穴麦粒灸结合疏肝泻火汤治疗气郁化火型中风后抑郁,可改善患者神经功能、抑郁状态,提高日常生活能力。
基金funded by the Beijing Municipal Administration of Hospitals Incubating Program(No.PZ2022032).
文摘Ojective:To explored the effectiveness and safety of acupuncture at back-shu points of five zang and Geshu(BL 17)for bipolar depression,and its mechanism from the aspect of the anti-inflammatory response.Background:Bipolar disorder is a very common,often misdiagnosed mental disorder strongly associated with comorbidity,disability,and premature mortality.Bipolar depression(ie,depressive episode in bipolar disorder)is poorly responsive to available treatments.Acupuncture at back-shu points of five zang and Geshu(BL 17),a prescription from Dr.Leting Wang,is a popular therapy for depression in China.Its effectiveness and safety for bipolar depression are yet to be verified by clinical studies.Methods:The study is a single-center,prospective,randomized controlled trial involving 72 patients diagnosed with bipolar depression.Participants will be randomized either to the study group or the control group in a 1:1 ratio.All participants will receive mood stabilizer therapy.In addition,the study group will receive acupuncture therapy at back-shu points of five zang and Geshu(BL 17),three times per week.The control group will orally take the antidepressant bupropion.Observation and intervention will last for 8 consecutive weeks.Outcome measurements include Hamilton Depression Rating Scale-17,Hamilton Anxiety Rating Scale,Clinical Global Impression Scale,Young Manic Rating Scale,Treatment Emergent Symptom Scale,serum levels of anti-inflammatory cytokines[interleukin-4(IL-40),IL-10,and transforming growth factor–β,pro-inflammatory cytokines(IL-1β,IL-6,and tumor necrosis factor–α),brain-derived neurotrophic factor,and C-reactive protein.Assessments will be conducted at baseline,first,second,fourth,and eighth weeks after randomization.Safety assessments will be performed throughout the study.Discussion:The results of this study are expected to verify the effectiveness and safety of acupuncture at back-shu points of five zang and Geshu(BL 17)for bipolar depression,and explore its therapeutic mechanisms from the point of anti-inflammation.
基金supported by Research and Development Project of Region Public Institution in Science and Technology Plan of Nanshan District of Shenzhen, No. 2015052~~
文摘Objective： To observe the clinical effect of liver-regulating and blood-tonifying acupuncture in the treatment of cervical spondylosis of vertebral artery type. Methods： A total of 60 cases meeting the inclusion criteria were randomized into an observation group and a control group, 30 cases in each group. Cases in the observation group received liver-regulating and blood-tonifying acupuncture, in which Jiaji （EX-B 2） points of C3_C7, Ganshu （BL 18） and Geshu （BL 17） were used; cases in the control group received routine acupuncture treatment in which jiaji （EX-B2） points of C3.C7 were used. Both groups received 5 times of treatment in a week with a 2-day rest, symptoms evaluation was done after 4 weeks of treatment, and then therapeutical effect was evaluated. Results： The total effective rate was 90.0% in the observation group, 73.3% in the control group, and inter-group comparison showed a statistical significance （P〈0.05）. After treatment, the symptoms and signs scores in both groups all substantially dropped, showing statistical significances （both P〈0.05）; inter-group comparison showed that the improvements in subscales of dizziness, pressing pain along vertebrae and revolve-cervix test in the observation group were superior than those in the control group, showing statistical significances （all P〈0.05）, while the inter-group comparisons of subscales of headache and vomiting and nause didn＇t show any statistical significances after treatment （both P〉0.05）. Conclusion： Liver-regulating and blood-tonifying acupuncture is effective in treating cervical spondylosis of vertebral artery type, and it can significantly improve patients＇ symptoms and signs.
文摘Objective:To observe and evaluate the clinical efficacy and safety of using pediatric Tuina(Chinese therapeutic massage),Tui-Pushing chest-back manipulation,in treating children with cough variant asthma(CVA).Methods:Seventy-two kids with CVA were divided into two groups using the random number table method,with 36 cases in each group.The control group received the conventional Tuina treatment,and the observation group received additional Tui-Pushing chest-back manipulation.The clinical efficacy and adverse reactions were observed and recorded for the two groups.Results:After three treatment courses,compared with the control group,the observation group showed advantages in the total effective rate,reducing the number and intensity of cough and improving the nature of cough(P<0.05).However,at the one-month follow-up,there were no significant differences between the two groups in these parameters(P>0.05).Regarding the adverse reaction rate,there was no significant between-group difference(P>0.05).Conclusion:It is effective and safe to use pediatric Tuina,Tui-Pushing chest-back manipulation,plus the conventional treatment protocol to treat CVA in children.
文摘Twenty-four cases of hiccup were treated by needle-embedding therapy at Geshu(BL 17),Ear Centre(MA-H 1)and Stomach(MA-IC).Results showed that hiccup disappeared in 21 cases,relieved in 1 case and changed little in 2 cases;that in some cases hiccup disappeared instantly after embedding needle.Itìs indicated that needle-embedding therapy is a quick and easy way to treat hiccup,with lasting effects.
文摘Objective. To investigate the effect of acupuncture or moxibustion at acupoint Geshu （BL 17） on raising leukocyte and promoting marrow proliferation. Methods.. Wister rats were selected to establish the leukopenia and immuno-suppression model by intraperitoneal injection of cytoxan （CTX）. After they were grouped and treated, leukocyte and marrow karyocyte were counted in different phases to evaluate the effect of acupuncture or moxibustion at acupoint Geshu （BL 17） on raising leukocyte and promoting marrow hematopoiesis. Results. Acupuncture or moxibustion at acupoint Geshu （BL 17） and routine western medicine could all significantly raise leukocyte and increase marrow karyocyte. The curative effect was better in moxibustion group than in acupuncture group and in routine western medicine group （P〈 0.05）. Conclusion. Moxibustion at acupoint Geshu （BL 17） can markedly raise peripheral blood leukocyte and marrow karyocyte of the leucopenia model in rats.
