Teeth affect not only oral problems but also facial morphology.In China,there are few reports about the influence of the third molars on the craniofacial morphology of Han youths.Using in vivo imaging software,3D reco...Teeth affect not only oral problems but also facial morphology.In China,there are few reports about the influence of the third molars on the craniofacial morphology of Han youths.Using in vivo imaging software,3D reconstruction of craniofacial CTs were performed on 32 Chinese Han youths without mandibular third molars and 25 Chinese Han youth with full mandibular third molars.The morphology of their mandible and mandibular tissue was measured to identify differences.Among the morphological characteristics of hard tissues,except for∠ANB,people with a full eruption of the mandibular third molars had statistically significantly larger angle indicators than people without the eruption of the third molars.The soft tissue indicators also showed statistically significant discrepancies in terms of morphological facial height,mouth to gnathion distance,lip height,and mouth breadth.The most influential index for mandibular third molars was length of symphysis,followed by the four indicators of soft tissue and mandible length and height.Morphology facial height,mouth to gnathion distance,lip height,and height of symphysis were moderately correlated.The experimental results show that among Han youth in North China,the third molar eruption has a widespread influence on mandibular morphology,especially in angle,length,and height indicators.It also has a certain influence on maxillofacial soft tissue morphology.These results can be applied to future clinical risk assessment of the wisdom teeth and forensic personal identification of the cranial and maxillofacial region.展开更多
Chromosomal evolution is widely considered an important driver of speciation because it can promote the establishment of reproductive barriers.Karyotypic reorganization is also expected to affect the mea n phe no type...Chromosomal evolution is widely considered an important driver of speciation because it can promote the establishment of reproductive barriers.Karyotypic reorganization is also expected to affect the mea n phe no type,as well as its developme nt and patter ns of phenotypic in tegrati on,through processes such as variation in genetic linkage between quantitative trait loci or between regulatory regions and their targets.Here we explore the relationship between chromosomal evolution and phenotypic integration by analyzing a well-known house mouse parapatric contact zone between a highly derived Robertsonian(Rb)race(2n=22)and populations with standard karyotype(2n=40).Populations with hybrid karyotypes are scattered throughout the hybrid zone connecting the two parental races.Using mandible shape data and geometric morphometries,we test the hypothesis that patter ns of in tegration progressively diverge from the"normal"integration pattern observed in the standard race as they accumulate Rb fusions.We find that the main pattern of integration observed between the posterior and anterior part of the mandible can be largely attributed to allometry.We find no support for a gradual increase in divergence from normal patterns of integration as fusions accumulate.Surprisingly,however,we find that the derived Rb race(2n=22)has a distinct allometric trajectory compared with the standard race.Our results suggest that either individual fusions disproportionately affect patterns of integration or that there are mechanisms which"purge"extreme variants in hybrids(e.g.reduced fitness of hybrid shape).展开更多
基金supported by Biological Anthropology Innovation Team Project of JZMU(Grant No.JYLJ201702)Liaoning Distinguished Professor Project(Grant No.LNTP20183501&LNTP201418701)。
文摘Teeth affect not only oral problems but also facial morphology.In China,there are few reports about the influence of the third molars on the craniofacial morphology of Han youths.Using in vivo imaging software,3D reconstruction of craniofacial CTs were performed on 32 Chinese Han youths without mandibular third molars and 25 Chinese Han youth with full mandibular third molars.The morphology of their mandible and mandibular tissue was measured to identify differences.Among the morphological characteristics of hard tissues,except for∠ANB,people with a full eruption of the mandibular third molars had statistically significantly larger angle indicators than people without the eruption of the third molars.The soft tissue indicators also showed statistically significant discrepancies in terms of morphological facial height,mouth to gnathion distance,lip height,and mouth breadth.The most influential index for mandibular third molars was length of symphysis,followed by the four indicators of soft tissue and mandible length and height.Morphology facial height,mouth to gnathion distance,lip height,and height of symphysis were moderately correlated.The experimental results show that among Han youth in North China,the third molar eruption has a widespread influence on mandibular morphology,especially in angle,length,and height indicators.It also has a certain influence on maxillofacial soft tissue morphology.These results can be applied to future clinical risk assessment of the wisdom teeth and forensic personal identification of the cranial and maxillofacial region.
基金the Ministry of Scientific Research and Education,Italy(MIUR).
文摘Chromosomal evolution is widely considered an important driver of speciation because it can promote the establishment of reproductive barriers.Karyotypic reorganization is also expected to affect the mea n phe no type,as well as its developme nt and patter ns of phenotypic in tegrati on,through processes such as variation in genetic linkage between quantitative trait loci or between regulatory regions and their targets.Here we explore the relationship between chromosomal evolution and phenotypic integration by analyzing a well-known house mouse parapatric contact zone between a highly derived Robertsonian(Rb)race(2n=22)and populations with standard karyotype(2n=40).Populations with hybrid karyotypes are scattered throughout the hybrid zone connecting the two parental races.Using mandible shape data and geometric morphometries,we test the hypothesis that patter ns of in tegration progressively diverge from the"normal"integration pattern observed in the standard race as they accumulate Rb fusions.We find that the main pattern of integration observed between the posterior and anterior part of the mandible can be largely attributed to allometry.We find no support for a gradual increase in divergence from normal patterns of integration as fusions accumulate.Surprisingly,however,we find that the derived Rb race(2n=22)has a distinct allometric trajectory compared with the standard race.Our results suggest that either individual fusions disproportionately affect patterns of integration or that there are mechanisms which"purge"extreme variants in hybrids(e.g.reduced fitness of hybrid shape).
