Accurate state of health(SOH)estimation is essential for the safe and reliable operation of lithium-ion batteries.However,existing methods face significant challenges,primarily because they rely on complete charge–di...Accurate state of health(SOH)estimation is essential for the safe and reliable operation of lithium-ion batteries.However,existing methods face significant challenges,primarily because they rely on complete charge–discharge cycles and fixed-form physical constraints,which limit adaptability to different chemistries and real-world conditions.To address these issues,this study proposes an approach that extracts features from segmented state of charge(SOC)intervals and integrates them into an enhanced physics-informed neural network(PINN).Specifically,voltage data within the 25%–75%SOC range during charging are used to derive statistical,time–frequency,and mechanism-based features that capture degradation trends.A hybrid PINN-Lasso-Transformer-BiLSTM architecture is developed,where Lasso regression enables sparse feature selection,and a nonlinear empirical degradation model is embedded as a learnable physical term within a dynamically scaled composite loss.This design adaptively balances data-driven accuracy with physical consistency,thereby enhancing estimation precision,robustness,and generalization.The results show that the proposed method outperforms conventional neural networks across four battery chemistries,achieving root mean square error and mean absolute error below 1%.Notably,features from partial charging segments exhibit higher robustness than those from full cycles.Furthermore,the model maintains strong performance under high temperatures and demonstrates excellent generalization capacity in transfer learning across chemistries,temperatures,and C-rates.This work establishes a scalable and interpretable solution for accurate SOH estimation under diverse practical operating conditions.展开更多
The soil-water retention curve(SWRC)plays a pivotal role in understanding water movement across numerous geological engineering applications.Despite significant advancements in theoretical modeling approaches,accurate...The soil-water retention curve(SWRC)plays a pivotal role in understanding water movement across numerous geological engineering applications.Despite significant advancements in theoretical modeling approaches,accurate prediction of SWRCs remains challenging due to the inherently sparse and incomplete nature of site-specific data.This study compiled a comprehensive dataset of SWRCs spanning a wide suction range from various published literature sources.Based on this dataset,multiple machine learning(ML)algorithms were employed to predict SWRCs.The performance of each algorithm was evaluated and ranked using four statistical indicators that quantify simulation accuracy.Feature importance analysis was subsequently conducted to reduce dimensionality by eliminating weakly correlated variables,thereby enhancing both model adaptability and computational efficiency.Following dimensionality reduction,a base learner pool was constructed and integrated through stacked generalization to create a multi-algorithm ensemble model.The proposed stacked model demonstrated robust performance in simulating SWRCs across diverse soil types,using only basic physical properties as inputs,achieving accuracy comparable to or marginally superior to the LightGBM model.The principal advantage of the stacked approach lies in its substantially improved accuracy within high suction ranges,effectively overcoming the limitations observed in LightGBM and enhancing the estimation under these conditions.This study provides valuable insights for researchers evaluating SWRCs through ML algorithms and demonstrates the potential of ensemble techniques in geotechnical prediction tasks.展开更多
In mixture experiments,the observed response is determined by the relative proportions of the components,consequently rendering the experimental region a simplex.This paper focuses primarily on the optimal designs of ...In mixture experiments,the observed response is determined by the relative proportions of the components,consequently rendering the experimental region a simplex.This paper focuses primarily on the optimal designs of mixture experiments that involve process variables.Prior research has extensively delved into optimal orthogonal block designs for some classic mixture models with process variables.Based on the framework of general blending models,this paper proposes a class of symmetric linear mixture models,which can be regarded as a generalization of many existing ones.Under the orthogonal blocking conditions,orthogonal block designs are devised through Latin squares in the presence of process variables.TheD-,A-,and E-optimality criteria are utilized to obtain optimal designs at the boundary of the simplex in the case of 3 components.As the values of the exponents change,numerically derived optimal design points are presented to illustrate the pattern of their variations,and to verify the consistency of the results with previous research on some specific symmetric general blending models.展开更多
Clouds play an important role in global atmospheric energy and water vapor budgets, and the low cloud simulations suffer from large biases in many atmospheric general circulation models. In this study, cloud microphys...Clouds play an important role in global atmospheric energy and water vapor budgets, and the low cloud simulations suffer from large biases in many atmospheric general circulation models. In this study, cloud microphysical processes such as raindrop evaporation and cloud water accretion in a double-moment six-class cloud microphysics scheme were revised to enhance the simulation of low clouds using the Global-Regional Integrated Forecast System(GRIST)model. The validation of the revised scheme using a single-column version of the GRIST demonstrated a reasonable reduction in liquid water biases. The revised parameterization simulated medium-and low-level cloud fractions that were in better agreement with the observations than the original scheme. Long-term global simulations indicate the mitigation of the originally overestimated low-level cloud fraction and cloud-water mixing ratio in mid-to high-latitude regions,primarily owing to enhanced accretion processes and weakened raindrop evaporation. The reduced low clouds with the revised scheme showed better consistency with satellite observations, particularly at mid-and high-latitudes. Further improvements can be observed in the simulated cloud shortwave radiative forcing and vertical distribution of total cloud cover. Annual precipitation in mid-latitude regions has also improved, particularly over the oceans, with significantly increased large-scale and decreased convective precipitation.展开更多
The overgeneralization of fear is associated with psychiatric disorders and cognitive decline.Recent studies have shown that engram cells in the dorsal dentate gyrus are integrated into functionally heterogeneous ense...The overgeneralization of fear is associated with psychiatric disorders and cognitive decline.Recent studies have shown that engram cells in the dorsal dentate gyrus are integrated into functionally heterogeneous ensembles that are involved in contextual fear memory generalization and discrimination.However,the intracellular signals that promote fear generalization remain to be fully elucidated.In this study,we labeled and manipulated the c-Fos+and Npas4+ensembles in the dorsal dentate gyrus that are activated by contextual fear conditioning using a robust activity marking system.The results showed that increasing the excitability of Fos-dependent robust activity marking by overexpressing NaChBac or decreasing the excitability of Npas4-dependent robust activity marking by overexpressing Kir2.1 promoted fear memory generalization.Furthermore,CRISPR-mediated downregulation of the autophagy-related Atg5 or Atg7 genes in dorsal dentate gyrus neurons inhibited activation of c-Fos,but not Npas4.Knockdown of Atg5 or Atg7 in the Fos-dependent robust activity marking or Npas4-dependent robust activity marking ensemble led to an increase in neuronal excitability and a decrease in spine density in both ensembles.However,Atg7 knockdown in the Fos-dependent robust activity marking ensemble promoted memory generalization,while knockdown of Atg5 or Atg7 in the Npas4-dependent robust activity marking ensemble increased anxiety levels.These results contribute to our understanding of how the varying plasticity of memory engrams is involved in regulating fear memory generalization and anxiety.展开更多
The construction of new agricultural science has put forward the core requirements of"interdisciplinary integration,service industry demand,and cultivation of composite talents"for the smart agriculture majo...The construction of new agricultural science has put forward the core requirements of"interdisciplinary integration,service industry demand,and cultivation of composite talents"for the smart agriculture major.The"integration of general and specialized education"is the key path to solve the problems of"prominent disciplinary barriers,fragmented knowledge structure,and weak practical ability"in the traditional curriculum system.In this paper,the College of Smart Agriculture from Yulin Normal University is taken as the research object.Based on the characteristics of regional agricultural industry and the positioning of professional education,the prominent problems in the current professional curriculum system of smart agriculture are analyzed,the construction concept of"strong foundation in general education,precise core in professional education,and breaking through boundaries in integrated education"is proposed,and a"three dimensions and four layers"integrated curriculum system framework for general and specialized education is constructed.Moreover,practical exploration is conducted from the aspects of curriculum module design,teaching mode innovation,and guarantee mechanism construction.Practice has shown that this curriculum system effectively enhances students'interdisciplinary application abilities and industry adaptability,and provides a practical sample for the reform of smart agriculture courses in local universities under the background of new agricultural science.展开更多
Making full use of the operator ordering method and the integration within ordered products,we obtain the analytical evolution law of a general quadratic state in the amplitude decay channel,and find that it is determ...Making full use of the operator ordering method and the integration within ordered products,we obtain the analytical evolution law of a general quadratic state in the amplitude decay channel,and find that it is determined not only by the decay rate of the amplitude decay channel but also by the coefficients of the initial quadratic state.Further,the quantum statistical properties of the initial quadratic state for amplitude decay are investigated via its average photon number and photon-counting distribution,and its Wigner distribution function evolution is discussed in detail.展开更多
Modern apprenticeship emphasizes strengthening school-enterprise cooperation,deepening the integration of production and education,and promoting the combination of work and study to achieve seamless connection between...Modern apprenticeship emphasizes strengthening school-enterprise cooperation,deepening the integration of production and education,and promoting the combination of work and study to achieve seamless connection between professional education and industrial needs,thereby improving the quality of talent training.This paper analyzes the current problems in the nursing talent training system,elaborates on the significance of cultivating nursing talents based on modern apprenticeship,and proposes new ideas for constructing a modern apprenticeship training model for nursing talents from the perspectives of“integrating general and specialized education,merging virtue and skills,and linking specialization and innovation”.The aim is to further promote the organic combination of nursing talent training goals and post needs,for reference only.展开更多
This study aims to reveal the prototypical argumentative patterns employed in situations where patient distrust arises in China.Based on the quantitative analysis of data from a general social survey,we focus on a dis...This study aims to reveal the prototypical argumentative patterns employed in situations where patient distrust arises in China.Based on the quantitative analysis of data from a general social survey,we focus on a distinctive phenomenon that while a majority of Chinese respondents trust the medical profession as a whole,significant distrust exists toward doctors'skills and ethics,particularly among older,urban,and higher income populations.Qualtatively,we employ Generalized Argumentation Theory to analyze Chinese clinical dialogues,identifying three kinds of prototypical argumentative patterns in situations of patient distrust.Methodologically,this article shows the value of combining statistical analysis with goal-oriented Generalized Argumentation research to reconcile the tricky trust phenomenon of Chinese doctor-patient communication.展开更多
The US 2024 general election ended with the Republican Party winning the presidential, House and Senate elections at the same time. In the presidential election, the Republican Party not only won more popular votes in...The US 2024 general election ended with the Republican Party winning the presidential, House and Senate elections at the same time. In the presidential election, the Republican Party not only won more popular votes in over 90% counties than in the 2020 general election, but also won seven highly contested swing States with greater edges. This also marks the first time since 2004 that the Republican Party has won a relative majority of popular votes in the presidential election.展开更多
The phenomenon of fear memory generalization can be defined as the expansion of an individual's originally specific fear responses to a similar yet genuinely harmless stimulus or situation subsequent to the occurr...The phenomenon of fear memory generalization can be defined as the expansion of an individual's originally specific fear responses to a similar yet genuinely harmless stimulus or situation subsequent to the occurrence of a traumatic event[1].Fear generalization within the normal range represents an adaptive evolutionary mechanism to facilitate prompt reactions to potential threats and to enhance the likelihood of survival.展开更多
BACKGROUND Currently,very few studies have examined the analgesic effectiveness and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for ...BACKGROUND Currently,very few studies have examined the analgesic effectiveness and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.AIM To investigate the analgesic effect and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.METHODS In this retrospective study,94 patients scheduled for laparoscopic minimally invasive surgery for inguinal hernia,admitted to Yiwu Central Hospital between May 2022 and May 2023,were divided into a control group(inhalation combined general anesthesia)and a treatment group(dexmedetomidine-assisted intrave-nous-inhalation combined general anesthesia).Perioperative indicators,analgesic effect,preoperative and postoperative 24-hours blood pressure(BP)and heart rate(HR),stress indicators,immune function levels,and adverse reactions were com-pared between the two groups.RESULTS Baseline data,including age,hernia location,place of residence,weight,monthly income,education level,and underlying diseases,were not significantly different between the two groups,indicating comparability(P>0.05).No significant difference was found in operation time and anesthesia time between the two groups(P>0.05).However,the treatment group exhibited a shorter postoperative urinary catheter removal time and hospital stay than the control group(P<0.05).Preoperatively,no significant differences were found in the visual analog scale(VAS)scores between the two groups(P>0.05).However,at 12,18,and 24 hours postoper-atively,the treatment group had significantly lower VAS scores than the control group(P<0.05).Although no significant differences in preoperative hemodynamic indicators were found between the two groups(P>0.05),both groups experienced some extent of changes in postoperative HR,diastolic BP(DBP),and systolic BP(SBP).Nevertheless,the treatment group showed smaller changes in HR,DBP,and SBP than the control group(P<0.05).Preoperative immune function indicators showed no significant differences between the two groups(P>0.05).However,postoperatively,the treatment group demonstrated higher levels of CD3+,CD4+,and CD4+/CD8+and lower levels of CD8+than the control group(P<0.05).The rates of adverse reactions were 6.38%and 23.40%in the treatment and control groups,respectively,revealing a significant difference(χ2=5.371,P=0.020).CONCLUSION Dexmedetomidine-assisted intravenous-inhalation combined general anesthesia can promote early recovery of patients undergoing laparoscopic minimally invasive surgery for inguinal hernia.It ensures stable blood flow,improves postoperative analgesic effects,reduces postoperative pain intensity,alleviates stress response,improves immune function,facilitates anesthesia recovery,and enhances safety.展开更多
BACKGROUND Subcutaneous implantable cardioverter-defibrillator(S-ICD)implantation requires effective anesthesia.General anesthesia(GA)carries risks like hemodynamic instability,while ultrasound-guided intercostal nerv...BACKGROUND Subcutaneous implantable cardioverter-defibrillator(S-ICD)implantation requires effective anesthesia.General anesthesia(GA)carries risks like hemodynamic instability,while ultrasound-guided intercostal nerve block(US-ICNB)may offer better pain control.This study hypothesized US-ICNB is superior in perioperative safety and pain management.AIM To compare perioperative outcomes of GA and US-ICNB in S-ICD implantation.METHODS This retrospective single-center study included 64 patients who received S-ICD implantation between February 2021 and December 2024.They were divided into GA and US-ICNB groups based on anesthesia type.Demographic data,perioperative parameters(operation time,pain scores,analgesic usage),and postoperative outcomes(complications,defibrillation events)were collected and analyzed.Statistical tests were used to compare the two groups.RESULTS This study included 64 patients(20 in the GA group and 44 in the US-ICNB group).Baseline left ventricular ejection fraction was significantly lower in the US-ICNB group(39.20%±12.00%vs 56.20%±11.50%in GA,P<0.001),while American Society of Anesthesiologists scores and comorbidities were comparable.US-ICNB showed superior pain control,with significantly lower numeric rating scale scores at 6-48 hours(P<0.001)and fewer patients requiring analgesics(P=0.02).The US-ICNB group had shorter operation times(P<0.001),total hospital stays(P<0.001),and later first analgesia times(P<0.001).No anesthesia-related complications occurred in either group.CONCLUSION Both anesthetic methods were safe in the short term.However,US-ICNB was superior in reducing operation and hospital stay times and alleviating peri-operative pain.It has high safety in S-ICD implantation and deserves further clinical promotion,though large-scale,multi-center,randomized controlled trials are needed to confirm these findings.展开更多
Face liveness detection is essential for securing biometric authentication systems against spoofing attacks,including printed photos,replay videos,and 3D masks.This study systematically evaluates pre-trained CNN model...Face liveness detection is essential for securing biometric authentication systems against spoofing attacks,including printed photos,replay videos,and 3D masks.This study systematically evaluates pre-trained CNN models—DenseNet201,VGG16,InceptionV3,ResNet50,VGG19,MobileNetV2,Xception,and InceptionResNetV2—leveraging transfer learning and fine-tuning to enhance liveness detection performance.The models were trained and tested on NUAA and Replay-Attack datasets,with cross-dataset generalization validated on SiW-MV2 to assess real-world adaptability.Performance was evaluated using accuracy,precision,recall,FAR,FRR,HTER,and specialized spoof detection metrics(APCER,NPCER,ACER).Fine-tuning significantly improved detection accuracy,with DenseNet201 achieving the highest performance(98.5%on NUAA,97.71%on Replay-Attack),while MobileNetV2 proved the most efficient model for real-time applications(latency:15 ms,memory usage:45 MB,energy consumption:30 mJ).A statistical significance analysis(paired t-tests,confidence intervals)validated these improvements.Cross-dataset experiments identified DenseNet201 and MobileNetV2 as the most generalizable architectures,with DenseNet201 achieving 86.4%accuracy on Replay-Attack when trained on NUAA,demonstrating robust feature extraction and adaptability.In contrast,ResNet50 showed lower generalization capabilities,struggling with dataset variability and complex spoofing attacks.These findings suggest that MobileNetV2 is well-suited for low-power applications,while DenseNet201 is ideal for high-security environments requiring superior accuracy.This research provides a framework for improving real-time face liveness detection,enhancing biometric security,and guiding future advancements in AI-driven anti-spoofing techniques.展开更多
Retinal blood vessel segmentation is crucial for diagnosing ocular and cardiovascular diseases.Although the introduction of U-Net in 2015 by Olaf Ronneberger significantly advanced this field,yet issues like limited t...Retinal blood vessel segmentation is crucial for diagnosing ocular and cardiovascular diseases.Although the introduction of U-Net in 2015 by Olaf Ronneberger significantly advanced this field,yet issues like limited training data,imbalance data distribution,and inadequate feature extraction persist,hindering both the segmentation performance and optimal model generalization.Addressing these critical issues,the DEFFA-Unet is proposed featuring an additional encoder to process domain-invariant pre-processed inputs,thereby improving both richer feature encoding and enhanced model generalization.A feature filtering fusion module is developed to ensure the precise feature filtering and robust hybrid feature fusion.In response to the task-specific need for higher precision where false positives are very costly,traditional skip connections are replaced with the attention-guided feature reconstructing fusion module.Additionally,innovative data augmentation and balancing methods are proposed to counter data scarcity and distribution imbalance,further boosting the robustness and generalization of the model.With a comprehensive suite of evaluation metrics,extensive validations on four benchmark datasets(DRIVE,CHASEDB1,STARE,and HRF)and an SLO dataset(IOSTAR),demonstrate the proposed method’s superiority over both baseline and state-of-the-art models.Particularly the proposed method significantly outperforms the compared methods in cross-validation model generalization.展开更多
Mingalarpar!On behalf of the Consulate-General of the Republic of the Union of Myanmar in Nanning,I would like to express my sincerest congratulations to CAEXPO on reaching the remarkable milestone of over 20 years—a...Mingalarpar!On behalf of the Consulate-General of the Republic of the Union of Myanmar in Nanning,I would like to express my sincerest congratulations to CAEXPO on reaching the remarkable milestone of over 20 years—an incredible journey filled with numerous achievements.展开更多
The object of this article is to study and develop the generalized fractional calcu- lus operators given by Saigo and Maeda in 1996. We establish generalized fractional calculus formulas involving the product of R-fun...The object of this article is to study and develop the generalized fractional calcu- lus operators given by Saigo and Maeda in 1996. We establish generalized fractional calculus formulas involving the product of R-function, Appell function F3 and a general class of poly- nomials. The results obtained provide unification and extension of the results given by Saxena et al. [13], Srivastava and Grag [17], Srivastava et al. [20], and etc. The results are obtained in compact form and are useful in preparing some tables of operators of fractional calculus. On account of the general nature of the Saigo-Maeda operators, R-function, and a general class of polynomials a large number of new and known results involving Saigo fractional calculus operators and several special functions notably H-function, /-function, Mittag-Leffier function, generalized Wright hypergeometric function, generalized Bessel-Maitland function follow as special cases of our main findings.展开更多
Objective:The study aimed to investigate the effect of relaxation techniques in reducing fear and anxiety in patients in need of general surgery.Materials and Methods:This quasi-experimental study with a pre-post cont...Objective:The study aimed to investigate the effect of relaxation techniques in reducing fear and anxiety in patients in need of general surgery.Materials and Methods:This quasi-experimental study with a pre-post control group design was conducted on 120 patients requiring general surgery at Saman Al-Hojjaj Hospital in Sirjan County.Patients were selected using convenience sampling and randomly assigned to the intervention group(n=60)and control group(n=60).The intervention group was taught box breathing and progressive muscle relaxation techniques by a senior psychiatric nursing expert for 15-20 min every 4 h until surgery.The control group received routine care for surgery.Data on fear and anxiety outcomes were collected using the Spielberger State-Trait Anxiety Inventory and the Surgical Fear Questionnaire.Results:The intervention group had a mean total fear score of 29.27±12.69 compared to 37.20±16.39 in the control group(P=0.012),with significant reductions in both short-term(13.57±5.93 vs.15.98±8.90;P=0.209,Cohen’s d=0.32)and long-term(15.70±7.19 vs.21.22±9.11;P=0.001,Cohen’s d=0.66)fear components(total fear:P=0.012,Cohen’s d=0.54).The total anxiety score was 91.88±6.28 in the control group and 93.60±3.62 in the intervention group,with trait anxiety significantly reduced in the intervention group(P=0.039,Cohen’s d=0.41)postintervention,but no significant change in state anxiety(P=0.577,Cohen’s d=0.16).Conclusions:Relaxation techniques significantly alleviate preoperative psychological distress,effectively reducing fear and anxiety in general surgery patients.These cost-effective,non-invasive methods enhance recovery and reduce healthcare costs.We recommend training healthcare providers to implement these techniques for optimal patient outcomes.展开更多
BACKGROUND The coronavirus disease 2019(COVID-19)outbreak lasted several months,having started in December 2019.This study aimed to report the impacts of various factors on the depression levels of the general public ...BACKGROUND The coronavirus disease 2019(COVID-19)outbreak lasted several months,having started in December 2019.This study aimed to report the impacts of various factors on the depression levels of the general public and ascertain how emotional measures could be affected by psychosocial factors during the COVID-19 pandemic.AIM To investigate the depression levels of the general public in China during the COVID-19 pandemic.METHODS A total of 2001 self-reported questionnaires about Beck Depression Inventory(BDI)were collected on August 22,2022 via the website.Each questionnaire included four levels of depression and other demographic information.The BDI scores and incidences of different depression levels were compared between various groups of respondents.χ2 analysis and the two-tailed t-test were used to assess categorical and continuous data,respectively.Multiple linear regressions and logistic regressions were employed for correlation analysis.RESULTS The averaged BDI score in this study was higher than that for the non-epidemic periods,as reported in previous studies.Even higher BDI scores and incidences of moderate and severe depression were recorded for people who were quarantined for suspected COVID-19 infection,compared to the respondents who were not quarantined.The participants who did not take protective measures were associated with higher BDI scores than those who made efforts to keep themselves relatively safer.Similarly,the people who did not return to work had higher BDI scores compared to those managed to.A significant association existed between the depression levels of the subgroups and each of the factors,except gender and location of residence.However,quarantine was the most relative predictor for depression levels,followed by failure to take preventive measures and losing a partner,either through divorce or death.CONCLUSION Based on these data,psychological interventions for the various subpopulations in the general public can be implemented during and after the COVID-19 pandemic.Other countries can also use the data as a reference.展开更多
General anesthesia(GA)is a pharmacologically induced,reversible state characterized by unconsciousness,amnesia,analgesia,and immobility in response to noxious stimuli.Accumulating evidence from animal models has eluci...General anesthesia(GA)is a pharmacologically induced,reversible state characterized by unconsciousness,amnesia,analgesia,and immobility in response to noxious stimuli.Accumulating evidence from animal models has elucidated diverse mechanisms of the action underlying GA,including disruption of large-scale brain network connectivity,regulation of multiple neural pathways,and modulation of specific receptors and ion channels.Despite advances in dissecting the neurobiological basis of anesthetic action,the precise cellular and circuit-level processes remain incompletely understood,limiting the development of safer and more effective strategies.Recent studies in Drosophila melanogaster,a genetically tractable model organism offering robust genetic analysis,advanced imaging capabilities,and compact neural architecture,have yielded critical insights into the conserved neurobiological mechanisms of GA,offering translational value for mammalian systems.This review outlines:1)experimental paradigms used to evaluate anesthetic sensitivity and behavioral responses in Drosophila;2)molecular targets and their mechanistic roles in mediating GA;and 3)neural circuit architectures and activity patterns shared by GA and sleep.Cross-species comparisons are integrated to highlight conserved mechanisms that may guide the development of more refined anesthetic strategies.展开更多
基金supported by the Shanghai Pilot Program for Basic Research(22T01400100-18)the National Natural Science Foundation of China(22278127 and 12447149)+1 种基金the Fundamental Research Funds for the Central Universities(2022ZFJH004)the Postdoctoral Fellowship Program of CPSF(GZB20250159).
文摘Accurate state of health(SOH)estimation is essential for the safe and reliable operation of lithium-ion batteries.However,existing methods face significant challenges,primarily because they rely on complete charge–discharge cycles and fixed-form physical constraints,which limit adaptability to different chemistries and real-world conditions.To address these issues,this study proposes an approach that extracts features from segmented state of charge(SOC)intervals and integrates them into an enhanced physics-informed neural network(PINN).Specifically,voltage data within the 25%–75%SOC range during charging are used to derive statistical,time–frequency,and mechanism-based features that capture degradation trends.A hybrid PINN-Lasso-Transformer-BiLSTM architecture is developed,where Lasso regression enables sparse feature selection,and a nonlinear empirical degradation model is embedded as a learnable physical term within a dynamically scaled composite loss.This design adaptively balances data-driven accuracy with physical consistency,thereby enhancing estimation precision,robustness,and generalization.The results show that the proposed method outperforms conventional neural networks across four battery chemistries,achieving root mean square error and mean absolute error below 1%.Notably,features from partial charging segments exhibit higher robustness than those from full cycles.Furthermore,the model maintains strong performance under high temperatures and demonstrates excellent generalization capacity in transfer learning across chemistries,temperatures,and C-rates.This work establishes a scalable and interpretable solution for accurate SOH estimation under diverse practical operating conditions.
基金the National Natural Science Foundation of China(Grant No.42272312)Ningbo Youth Science and Technology Innovation Talent Project(Grant No.2024QL057)the Zhejiang Provincial Xinmiao Talents Program(Grant No.2024R405B093).
文摘The soil-water retention curve(SWRC)plays a pivotal role in understanding water movement across numerous geological engineering applications.Despite significant advancements in theoretical modeling approaches,accurate prediction of SWRCs remains challenging due to the inherently sparse and incomplete nature of site-specific data.This study compiled a comprehensive dataset of SWRCs spanning a wide suction range from various published literature sources.Based on this dataset,multiple machine learning(ML)algorithms were employed to predict SWRCs.The performance of each algorithm was evaluated and ranked using four statistical indicators that quantify simulation accuracy.Feature importance analysis was subsequently conducted to reduce dimensionality by eliminating weakly correlated variables,thereby enhancing both model adaptability and computational efficiency.Following dimensionality reduction,a base learner pool was constructed and integrated through stacked generalization to create a multi-algorithm ensemble model.The proposed stacked model demonstrated robust performance in simulating SWRCs across diverse soil types,using only basic physical properties as inputs,achieving accuracy comparable to or marginally superior to the LightGBM model.The principal advantage of the stacked approach lies in its substantially improved accuracy within high suction ranges,effectively overcoming the limitations observed in LightGBM and enhancing the estimation under these conditions.This study provides valuable insights for researchers evaluating SWRCs through ML algorithms and demonstrates the potential of ensemble techniques in geotechnical prediction tasks.
基金supported by the National Natural Science Foundation of China[grant numbers 12071329,12471246].
文摘In mixture experiments,the observed response is determined by the relative proportions of the components,consequently rendering the experimental region a simplex.This paper focuses primarily on the optimal designs of mixture experiments that involve process variables.Prior research has extensively delved into optimal orthogonal block designs for some classic mixture models with process variables.Based on the framework of general blending models,this paper proposes a class of symmetric linear mixture models,which can be regarded as a generalization of many existing ones.Under the orthogonal blocking conditions,orthogonal block designs are devised through Latin squares in the presence of process variables.TheD-,A-,and E-optimality criteria are utilized to obtain optimal designs at the boundary of the simplex in the case of 3 components.As the values of the exponents change,numerically derived optimal design points are presented to illustrate the pattern of their variations,and to verify the consistency of the results with previous research on some specific symmetric general blending models.
基金National Natural Science Foundation of China(42375153,42105153,42205157)Development of Science and Technology at Chinese Academy of Meteorological Sciences(2023KJ038)。
文摘Clouds play an important role in global atmospheric energy and water vapor budgets, and the low cloud simulations suffer from large biases in many atmospheric general circulation models. In this study, cloud microphysical processes such as raindrop evaporation and cloud water accretion in a double-moment six-class cloud microphysics scheme were revised to enhance the simulation of low clouds using the Global-Regional Integrated Forecast System(GRIST)model. The validation of the revised scheme using a single-column version of the GRIST demonstrated a reasonable reduction in liquid water biases. The revised parameterization simulated medium-and low-level cloud fractions that were in better agreement with the observations than the original scheme. Long-term global simulations indicate the mitigation of the originally overestimated low-level cloud fraction and cloud-water mixing ratio in mid-to high-latitude regions,primarily owing to enhanced accretion processes and weakened raindrop evaporation. The reduced low clouds with the revised scheme showed better consistency with satellite observations, particularly at mid-and high-latitudes. Further improvements can be observed in the simulated cloud shortwave radiative forcing and vertical distribution of total cloud cover. Annual precipitation in mid-latitude regions has also improved, particularly over the oceans, with significantly increased large-scale and decreased convective precipitation.
基金the STI2030-Major Projects,Nos.2021ZD0203500(to FW),2021ZD0202100(to XL)the National Natural Science Foundation of China,Nos.32222033(to FW),32330041(to LM)and 82021002(to LM),32171041(to XL)and 32450102(to XL)CAMS Innovation Fund for Medical Sciences,No.2021-I2M-5-009(to LM and XL).
文摘The overgeneralization of fear is associated with psychiatric disorders and cognitive decline.Recent studies have shown that engram cells in the dorsal dentate gyrus are integrated into functionally heterogeneous ensembles that are involved in contextual fear memory generalization and discrimination.However,the intracellular signals that promote fear generalization remain to be fully elucidated.In this study,we labeled and manipulated the c-Fos+and Npas4+ensembles in the dorsal dentate gyrus that are activated by contextual fear conditioning using a robust activity marking system.The results showed that increasing the excitability of Fos-dependent robust activity marking by overexpressing NaChBac or decreasing the excitability of Npas4-dependent robust activity marking by overexpressing Kir2.1 promoted fear memory generalization.Furthermore,CRISPR-mediated downregulation of the autophagy-related Atg5 or Atg7 genes in dorsal dentate gyrus neurons inhibited activation of c-Fos,but not Npas4.Knockdown of Atg5 or Atg7 in the Fos-dependent robust activity marking or Npas4-dependent robust activity marking ensemble led to an increase in neuronal excitability and a decrease in spine density in both ensembles.However,Atg7 knockdown in the Fos-dependent robust activity marking ensemble promoted memory generalization,while knockdown of Atg5 or Atg7 in the Npas4-dependent robust activity marking ensemble increased anxiety levels.These results contribute to our understanding of how the varying plasticity of memory engrams is involved in regulating fear memory generalization and anxiety.
基金Supported by the Autonomous Region-level Research and Practice Projects for New Engineering,New Medicine,New Agriculture,and New Humanities of Guangxi Department of Education(XNK202409)the Undergraduate Teaching Reform Project of Guangxi Higher Education(2024JGB332+1 种基金2024JGA304)the Guangxi Degree and Graduate Education Reform Project(JGY2025382).
文摘The construction of new agricultural science has put forward the core requirements of"interdisciplinary integration,service industry demand,and cultivation of composite talents"for the smart agriculture major.The"integration of general and specialized education"is the key path to solve the problems of"prominent disciplinary barriers,fragmented knowledge structure,and weak practical ability"in the traditional curriculum system.In this paper,the College of Smart Agriculture from Yulin Normal University is taken as the research object.Based on the characteristics of regional agricultural industry and the positioning of professional education,the prominent problems in the current professional curriculum system of smart agriculture are analyzed,the construction concept of"strong foundation in general education,precise core in professional education,and breaking through boundaries in integrated education"is proposed,and a"three dimensions and four layers"integrated curriculum system framework for general and specialized education is constructed.Moreover,practical exploration is conducted from the aspects of curriculum module design,teaching mode innovation,and guarantee mechanism construction.Practice has shown that this curriculum system effectively enhances students'interdisciplinary application abilities and industry adaptability,and provides a practical sample for the reform of smart agriculture courses in local universities under the background of new agricultural science.
文摘Making full use of the operator ordering method and the integration within ordered products,we obtain the analytical evolution law of a general quadratic state in the amplitude decay channel,and find that it is determined not only by the decay rate of the amplitude decay channel but also by the coefficients of the initial quadratic state.Further,the quantum statistical properties of the initial quadratic state for amplitude decay are investigated via its average photon number and photon-counting distribution,and its Wigner distribution function evolution is discussed in detail.
基金2025 Shanghai Secondary Vocational School Curriculum and Teaching Reform Research Project(Project No.:2025K-03)。
文摘Modern apprenticeship emphasizes strengthening school-enterprise cooperation,deepening the integration of production and education,and promoting the combination of work and study to achieve seamless connection between professional education and industrial needs,thereby improving the quality of talent training.This paper analyzes the current problems in the nursing talent training system,elaborates on the significance of cultivating nursing talents based on modern apprenticeship,and proposes new ideas for constructing a modern apprenticeship training model for nursing talents from the perspectives of“integrating general and specialized education,merging virtue and skills,and linking specialization and innovation”.The aim is to further promote the organic combination of nursing talent training goals and post needs,for reference only.
基金supported by the Fundamental Research Funds for the Chinese MOE Project of Key Research Institute of Humanities and Social Sciences at Universities(22JJD720022)the Central Universities of Jinan University(Grant No.23JNQMX55).
文摘This study aims to reveal the prototypical argumentative patterns employed in situations where patient distrust arises in China.Based on the quantitative analysis of data from a general social survey,we focus on a distinctive phenomenon that while a majority of Chinese respondents trust the medical profession as a whole,significant distrust exists toward doctors'skills and ethics,particularly among older,urban,and higher income populations.Qualtatively,we employ Generalized Argumentation Theory to analyze Chinese clinical dialogues,identifying three kinds of prototypical argumentative patterns in situations of patient distrust.Methodologically,this article shows the value of combining statistical analysis with goal-oriented Generalized Argumentation research to reconcile the tricky trust phenomenon of Chinese doctor-patient communication.
文摘The US 2024 general election ended with the Republican Party winning the presidential, House and Senate elections at the same time. In the presidential election, the Republican Party not only won more popular votes in over 90% counties than in the 2020 general election, but also won seven highly contested swing States with greater edges. This also marks the first time since 2004 that the Republican Party has won a relative majority of popular votes in the presidential election.
基金supported by the Shandong Provincial Natural Science Foundation(ZR2022QH144).
文摘The phenomenon of fear memory generalization can be defined as the expansion of an individual's originally specific fear responses to a similar yet genuinely harmless stimulus or situation subsequent to the occurrence of a traumatic event[1].Fear generalization within the normal range represents an adaptive evolutionary mechanism to facilitate prompt reactions to potential threats and to enhance the likelihood of survival.
文摘BACKGROUND Currently,very few studies have examined the analgesic effectiveness and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.AIM To investigate the analgesic effect and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.METHODS In this retrospective study,94 patients scheduled for laparoscopic minimally invasive surgery for inguinal hernia,admitted to Yiwu Central Hospital between May 2022 and May 2023,were divided into a control group(inhalation combined general anesthesia)and a treatment group(dexmedetomidine-assisted intrave-nous-inhalation combined general anesthesia).Perioperative indicators,analgesic effect,preoperative and postoperative 24-hours blood pressure(BP)and heart rate(HR),stress indicators,immune function levels,and adverse reactions were com-pared between the two groups.RESULTS Baseline data,including age,hernia location,place of residence,weight,monthly income,education level,and underlying diseases,were not significantly different between the two groups,indicating comparability(P>0.05).No significant difference was found in operation time and anesthesia time between the two groups(P>0.05).However,the treatment group exhibited a shorter postoperative urinary catheter removal time and hospital stay than the control group(P<0.05).Preoperatively,no significant differences were found in the visual analog scale(VAS)scores between the two groups(P>0.05).However,at 12,18,and 24 hours postoper-atively,the treatment group had significantly lower VAS scores than the control group(P<0.05).Although no significant differences in preoperative hemodynamic indicators were found between the two groups(P>0.05),both groups experienced some extent of changes in postoperative HR,diastolic BP(DBP),and systolic BP(SBP).Nevertheless,the treatment group showed smaller changes in HR,DBP,and SBP than the control group(P<0.05).Preoperative immune function indicators showed no significant differences between the two groups(P>0.05).However,postoperatively,the treatment group demonstrated higher levels of CD3+,CD4+,and CD4+/CD8+and lower levels of CD8+than the control group(P<0.05).The rates of adverse reactions were 6.38%and 23.40%in the treatment and control groups,respectively,revealing a significant difference(χ2=5.371,P=0.020).CONCLUSION Dexmedetomidine-assisted intravenous-inhalation combined general anesthesia can promote early recovery of patients undergoing laparoscopic minimally invasive surgery for inguinal hernia.It ensures stable blood flow,improves postoperative analgesic effects,reduces postoperative pain intensity,alleviates stress response,improves immune function,facilitates anesthesia recovery,and enhances safety.
文摘BACKGROUND Subcutaneous implantable cardioverter-defibrillator(S-ICD)implantation requires effective anesthesia.General anesthesia(GA)carries risks like hemodynamic instability,while ultrasound-guided intercostal nerve block(US-ICNB)may offer better pain control.This study hypothesized US-ICNB is superior in perioperative safety and pain management.AIM To compare perioperative outcomes of GA and US-ICNB in S-ICD implantation.METHODS This retrospective single-center study included 64 patients who received S-ICD implantation between February 2021 and December 2024.They were divided into GA and US-ICNB groups based on anesthesia type.Demographic data,perioperative parameters(operation time,pain scores,analgesic usage),and postoperative outcomes(complications,defibrillation events)were collected and analyzed.Statistical tests were used to compare the two groups.RESULTS This study included 64 patients(20 in the GA group and 44 in the US-ICNB group).Baseline left ventricular ejection fraction was significantly lower in the US-ICNB group(39.20%±12.00%vs 56.20%±11.50%in GA,P<0.001),while American Society of Anesthesiologists scores and comorbidities were comparable.US-ICNB showed superior pain control,with significantly lower numeric rating scale scores at 6-48 hours(P<0.001)and fewer patients requiring analgesics(P=0.02).The US-ICNB group had shorter operation times(P<0.001),total hospital stays(P<0.001),and later first analgesia times(P<0.001).No anesthesia-related complications occurred in either group.CONCLUSION Both anesthetic methods were safe in the short term.However,US-ICNB was superior in reducing operation and hospital stay times and alleviating peri-operative pain.It has high safety in S-ICD implantation and deserves further clinical promotion,though large-scale,multi-center,randomized controlled trials are needed to confirm these findings.
基金funded by Centre for Advanced Modelling and Geospatial Information Systems(CAMGIS),Faculty of Engineering and IT,University of Technology Sydney.Moreover,Ongoing Research Funding Program(ORF-2025-14)King Saud University,Riyadh,Saudi Arabia,under Project ORF-2025-。
文摘Face liveness detection is essential for securing biometric authentication systems against spoofing attacks,including printed photos,replay videos,and 3D masks.This study systematically evaluates pre-trained CNN models—DenseNet201,VGG16,InceptionV3,ResNet50,VGG19,MobileNetV2,Xception,and InceptionResNetV2—leveraging transfer learning and fine-tuning to enhance liveness detection performance.The models were trained and tested on NUAA and Replay-Attack datasets,with cross-dataset generalization validated on SiW-MV2 to assess real-world adaptability.Performance was evaluated using accuracy,precision,recall,FAR,FRR,HTER,and specialized spoof detection metrics(APCER,NPCER,ACER).Fine-tuning significantly improved detection accuracy,with DenseNet201 achieving the highest performance(98.5%on NUAA,97.71%on Replay-Attack),while MobileNetV2 proved the most efficient model for real-time applications(latency:15 ms,memory usage:45 MB,energy consumption:30 mJ).A statistical significance analysis(paired t-tests,confidence intervals)validated these improvements.Cross-dataset experiments identified DenseNet201 and MobileNetV2 as the most generalizable architectures,with DenseNet201 achieving 86.4%accuracy on Replay-Attack when trained on NUAA,demonstrating robust feature extraction and adaptability.In contrast,ResNet50 showed lower generalization capabilities,struggling with dataset variability and complex spoofing attacks.These findings suggest that MobileNetV2 is well-suited for low-power applications,while DenseNet201 is ideal for high-security environments requiring superior accuracy.This research provides a framework for improving real-time face liveness detection,enhancing biometric security,and guiding future advancements in AI-driven anti-spoofing techniques.
文摘Retinal blood vessel segmentation is crucial for diagnosing ocular and cardiovascular diseases.Although the introduction of U-Net in 2015 by Olaf Ronneberger significantly advanced this field,yet issues like limited training data,imbalance data distribution,and inadequate feature extraction persist,hindering both the segmentation performance and optimal model generalization.Addressing these critical issues,the DEFFA-Unet is proposed featuring an additional encoder to process domain-invariant pre-processed inputs,thereby improving both richer feature encoding and enhanced model generalization.A feature filtering fusion module is developed to ensure the precise feature filtering and robust hybrid feature fusion.In response to the task-specific need for higher precision where false positives are very costly,traditional skip connections are replaced with the attention-guided feature reconstructing fusion module.Additionally,innovative data augmentation and balancing methods are proposed to counter data scarcity and distribution imbalance,further boosting the robustness and generalization of the model.With a comprehensive suite of evaluation metrics,extensive validations on four benchmark datasets(DRIVE,CHASEDB1,STARE,and HRF)and an SLO dataset(IOSTAR),demonstrate the proposed method’s superiority over both baseline and state-of-the-art models.Particularly the proposed method significantly outperforms the compared methods in cross-validation model generalization.
文摘Mingalarpar!On behalf of the Consulate-General of the Republic of the Union of Myanmar in Nanning,I would like to express my sincerest congratulations to CAEXPO on reaching the remarkable milestone of over 20 years—an incredible journey filled with numerous achievements.
基金NBHM Department of Atomic Energy,Government of India,Mumbai for the finanicai assistance under PDF sanction no.2/40(37)/2014/R&D-II/14131
文摘The object of this article is to study and develop the generalized fractional calcu- lus operators given by Saigo and Maeda in 1996. We establish generalized fractional calculus formulas involving the product of R-function, Appell function F3 and a general class of poly- nomials. The results obtained provide unification and extension of the results given by Saxena et al. [13], Srivastava and Grag [17], Srivastava et al. [20], and etc. The results are obtained in compact form and are useful in preparing some tables of operators of fractional calculus. On account of the general nature of the Saigo-Maeda operators, R-function, and a general class of polynomials a large number of new and known results involving Saigo fractional calculus operators and several special functions notably H-function, /-function, Mittag-Leffier function, generalized Wright hypergeometric function, generalized Bessel-Maitland function follow as special cases of our main findings.
基金funded by Sirjan Medical Sciences Faculty,Sirjan,Iran.(Project code:402000018).
文摘Objective:The study aimed to investigate the effect of relaxation techniques in reducing fear and anxiety in patients in need of general surgery.Materials and Methods:This quasi-experimental study with a pre-post control group design was conducted on 120 patients requiring general surgery at Saman Al-Hojjaj Hospital in Sirjan County.Patients were selected using convenience sampling and randomly assigned to the intervention group(n=60)and control group(n=60).The intervention group was taught box breathing and progressive muscle relaxation techniques by a senior psychiatric nursing expert for 15-20 min every 4 h until surgery.The control group received routine care for surgery.Data on fear and anxiety outcomes were collected using the Spielberger State-Trait Anxiety Inventory and the Surgical Fear Questionnaire.Results:The intervention group had a mean total fear score of 29.27±12.69 compared to 37.20±16.39 in the control group(P=0.012),with significant reductions in both short-term(13.57±5.93 vs.15.98±8.90;P=0.209,Cohen’s d=0.32)and long-term(15.70±7.19 vs.21.22±9.11;P=0.001,Cohen’s d=0.66)fear components(total fear:P=0.012,Cohen’s d=0.54).The total anxiety score was 91.88±6.28 in the control group and 93.60±3.62 in the intervention group,with trait anxiety significantly reduced in the intervention group(P=0.039,Cohen’s d=0.41)postintervention,but no significant change in state anxiety(P=0.577,Cohen’s d=0.16).Conclusions:Relaxation techniques significantly alleviate preoperative psychological distress,effectively reducing fear and anxiety in general surgery patients.These cost-effective,non-invasive methods enhance recovery and reduce healthcare costs.We recommend training healthcare providers to implement these techniques for optimal patient outcomes.
文摘BACKGROUND The coronavirus disease 2019(COVID-19)outbreak lasted several months,having started in December 2019.This study aimed to report the impacts of various factors on the depression levels of the general public and ascertain how emotional measures could be affected by psychosocial factors during the COVID-19 pandemic.AIM To investigate the depression levels of the general public in China during the COVID-19 pandemic.METHODS A total of 2001 self-reported questionnaires about Beck Depression Inventory(BDI)were collected on August 22,2022 via the website.Each questionnaire included four levels of depression and other demographic information.The BDI scores and incidences of different depression levels were compared between various groups of respondents.χ2 analysis and the two-tailed t-test were used to assess categorical and continuous data,respectively.Multiple linear regressions and logistic regressions were employed for correlation analysis.RESULTS The averaged BDI score in this study was higher than that for the non-epidemic periods,as reported in previous studies.Even higher BDI scores and incidences of moderate and severe depression were recorded for people who were quarantined for suspected COVID-19 infection,compared to the respondents who were not quarantined.The participants who did not take protective measures were associated with higher BDI scores than those who made efforts to keep themselves relatively safer.Similarly,the people who did not return to work had higher BDI scores compared to those managed to.A significant association existed between the depression levels of the subgroups and each of the factors,except gender and location of residence.However,quarantine was the most relative predictor for depression levels,followed by failure to take preventive measures and losing a partner,either through divorce or death.CONCLUSION Based on these data,psychological interventions for the various subpopulations in the general public can be implemented during and after the COVID-19 pandemic.Other countries can also use the data as a reference.
基金supported by the National Natural Science Foundation of China(32371063,82341288,32071009)to C.L.Guangdong Basic and Applied Basic Research Foundation(2024A1515011500)to C.L.
文摘General anesthesia(GA)is a pharmacologically induced,reversible state characterized by unconsciousness,amnesia,analgesia,and immobility in response to noxious stimuli.Accumulating evidence from animal models has elucidated diverse mechanisms of the action underlying GA,including disruption of large-scale brain network connectivity,regulation of multiple neural pathways,and modulation of specific receptors and ion channels.Despite advances in dissecting the neurobiological basis of anesthetic action,the precise cellular and circuit-level processes remain incompletely understood,limiting the development of safer and more effective strategies.Recent studies in Drosophila melanogaster,a genetically tractable model organism offering robust genetic analysis,advanced imaging capabilities,and compact neural architecture,have yielded critical insights into the conserved neurobiological mechanisms of GA,offering translational value for mammalian systems.This review outlines:1)experimental paradigms used to evaluate anesthetic sensitivity and behavioral responses in Drosophila;2)molecular targets and their mechanistic roles in mediating GA;and 3)neural circuit architectures and activity patterns shared by GA and sleep.Cross-species comparisons are integrated to highlight conserved mechanisms that may guide the development of more refined anesthetic strategies.
