Objective To study the chemical constituents of the fungus Ganoderma cochlear. Methods The compounds were isolated by using MCI gel CHP 20P, Sephadex LH-20, RP-18 column chromatography, and preparative TLC. The struct...Objective To study the chemical constituents of the fungus Ganoderma cochlear. Methods The compounds were isolated by using MCI gel CHP 20P, Sephadex LH-20, RP-18 column chromatography, and preparative TLC. The structures were identified by means of spectroscopic methods. Results Two phenolic normeroterpenoid and meroterpenoid, cochlearols C and D （1 and 2）, together with six benzene derivatives, 3- methoxy-4-hydroxy-phenylethanol （3）, 4-hydroxyacetophenone （4）, p-hydroxycinnamic methyl ester （5）, 2-methoxy-4-hydroxybenzaldehyde （6）, 4-hydroxy-3-methoxy benzoic acid （7）, and 2-hydroxy-5-ethoxybenzoic acid （8）, were isolated from the fruiting bodies of Ganoderma cochlear. Conclusion Compounds 1 and 2 are new phenolic normeroterpenoid and meroterpenoid, respectively.展开更多
基金NSFC-Joint Foundation of Yunnan Province(U1202222)National Natural Science Foundation of China(21472199)+1 种基金a project from State Key Laboratory of Phytochemistry and Plant Resources in West ChinaKunming Institute of Botany(P2013-ZZ03)
文摘Objective To study the chemical constituents of the fungus Ganoderma cochlear. Methods The compounds were isolated by using MCI gel CHP 20P, Sephadex LH-20, RP-18 column chromatography, and preparative TLC. The structures were identified by means of spectroscopic methods. Results Two phenolic normeroterpenoid and meroterpenoid, cochlearols C and D （1 and 2）, together with six benzene derivatives, 3- methoxy-4-hydroxy-phenylethanol （3）, 4-hydroxyacetophenone （4）, p-hydroxycinnamic methyl ester （5）, 2-methoxy-4-hydroxybenzaldehyde （6）, 4-hydroxy-3-methoxy benzoic acid （7）, and 2-hydroxy-5-ethoxybenzoic acid （8）, were isolated from the fruiting bodies of Ganoderma cochlear. Conclusion Compounds 1 and 2 are new phenolic normeroterpenoid and meroterpenoid, respectively.
