OBJECTIVE:To compare the changes in gait parameters before and after the treatment of lateral ankle sprain using the rotating-pulling-poking manipulation, and explore the potential bio-mechanical mechanism of this man...OBJECTIVE:To compare the changes in gait parameters before and after the treatment of lateral ankle sprain using the rotating-pulling-poking manipulation, and explore the potential bio-mechanical mechanism of this manipulation. METHODS:Forty patients with lateral ankle sprains were randomly divided into two groups in a 1∶1 ratio using a random number table. The experimental group were treated by rotating-pulling-poking manipulation and elastic bandage external fixation, while the control group were treated by ice compress and elastic bandage external fixation. The treatment courses of the two groups were both 2 weeks. We used a three-dimensional motion capture system for kinematic measurements and a Bertec gait analysis force measurement system for mechanical measurements, and compared the changes in gait parameters between the two groups of patients before and after treatment. RESULTS:Intragroup comparison showed that the support time, swing time, peak of back extension, peak of plantar flexion, peak of toe pedal force, and peak of heel landing force of the affected feet in the experimental group were significantly improved compared to those before treatment(P < 0.05). The swing time of the affected feet in the control group was significantly improved compared to that before treatment(P < 0.05). The inter group comparison showed that the gait speed, stride length, peak of back extension, peak of plantar flexion, peak of toe pedal force, and peak of heel landing force of the affected feet in the experimental group were significantly better than those in the control group(P < 0.05). CONCLUSIONS:The rotating-pulling-poking manipulation can effectively improve the patient's gait and range of motion of the affected ankle joint, and enhance the negative gravity in the vertical direction of the affected foot, and the braking and driving forces in the front and back directions. This may be the potential biomechanical mechanism of the rotating-pulling-poking manipulation for treating lateral ankle sprain.展开更多
An experiment was carried out in the key laboratory for Technique Diagnosis and Function Assessment of Winter Sports of China to investigate the differences in gait characteristics between healthy children and childre...An experiment was carried out in the key laboratory for Technique Diagnosis and Function Assessment of Winter Sports of China to investigate the differences in gait characteristics between healthy children and children with spastic hemiplegic cerebral palsy. With permission of their parents, 200 healthy children aged 3 to 6 years in the kindergarten of Northeastern University were enrolled in this experiment. Twenty children aged 3 to 6 years with spastic hemiplegic cerebral palsy from Shengjing Hospital, China were also enrolled in this experiment. Standard data were collected by simultaneously recording gait information from two digital cameras. DVracker was used to analyze the standard data. The children with hemiplegic cerebra palsy had a longer gait cycle, slower walking speed, and longer support phase than did the healthy children. The support phase was longer than the swing phase in the children with hemiplegic cerebral palsy. There were significant differences in the angles of the hip, knee, and ankle joint between children with cerebral palsy and healthy children at the moment of touching the ground and buffering, and during pedal extension. Children with hemiplegic cerebral palsy had poor motor coordination during walking, which basically resulted in a short stride, high stride frequency to maintain speed, more obvious swing, and poor stability.展开更多
Assessment of locomotion recovery in preclinical studies of experimental spinal cord injury remains challenging. We studied the CatWalk XT■gait analysis for evaluating hindlimb functional recovery in a widely used an...Assessment of locomotion recovery in preclinical studies of experimental spinal cord injury remains challenging. We studied the CatWalk XT■gait analysis for evaluating hindlimb functional recovery in a widely used and clinically relevant thoracic contusion/compression spinal cord injury model in rats. Rats were randomly assigned to either a T9 spinal cord injury or sham laminectomy. Locomotion recovery was assessed using the Basso, Beattie, and Bresnahan open field rating scale and the CatWalk XT■gait analysis. To determine the potential bias from weight changes, corrected hindlimb(H) values(divided by the unaffected forelimb(F) values) were calculated. Six weeks after injury, cyst formation, astrogliosis, and the deposition of chondroitin sulfate glycosaminoglycans were assessed by immunohistochemistry staining. Compared with the baseline, a significant spontaneous recovery could be observed in the CatWalk XT■parameters max intensity, mean intensity, max intensity at%, and max contact mean intensity from 4 weeks after injury onwards. Of note, corrected values(H/F) of CatWalk XT■parameters showed a significantly less vulnerability to the weight changes than absolute values, specifically in static parameters. The corrected CatWalk XT■parameters were positively correlated with the Basso, Beattie, and Bresnahan rating scale scores, cyst formation, the immunointensity of astrogliosis and chondroitin sulfate glycosaminoglycan deposition. The CatWalk XT■gait analysis and especially its static parameters, therefore, seem to be highly useful in assessing spontaneous recovery of hindlimb function after severe thoracic spinal cord injury. Because many CatWalk XT■parameters of the hindlimbs seem to be affected by body weight changes, using their corrected values might be a valuable option to improve this dependency.展开更多
AIM To describe,using gait analysis,the development of spinal motion in the growing child.METHODS Thirty-six healthy children aged from 3 to 16 years old were included in this study for a gait analysis(9m-walk).Variou...AIM To describe,using gait analysis,the development of spinal motion in the growing child.METHODS Thirty-six healthy children aged from 3 to 16 years old were included in this study for a gait analysis(9m-walk).Various kinematic parameters were recorded and analyzed such as thoracic angle(TA),lumbar angle(LA)and sagittal vertical axis(SVA).The kinetic parameters were the net reaction moments(N.m/kg)at the thoracolumbar and lumbosacral junctions.RESULTS TA and LA curves were not statistically correlated to the age(respectively,P=0.32 and P=0.41).SVA increased significantly with age(P<0.001).Moments in sagittal plane at the lumbosacral junction were statistically correlated to the age(P=0.003),underlining the fact that sagittal mechanical constraints at the lumbosacral junction increase with age.Moments in transversal plane at the thoracolumbar and lumbosacral junctions were statistically correlated to the age(P=0.0002and P=0.0006),revealing that transversal mechanical constraints decrease with age.CONCLUSION The kinetic analysis showed that during growth,a decrease of torsional constraint occurs while an increase of sagittal constraint is observed.These changes in spine biomechanics are related to the crucial role of the trunk for bipedalism acquisition,allowing stabilization despite lower limbs immaturity.With the acquisition of mature gait,the spine will mainly undergo constraints in the sagittal plane.展开更多
Medical research on neurologic ailments requires representative animal models to validate treatments before they are translated to human clinical trials.Rodents are the predominant animal model used in neurological re...Medical research on neurologic ailments requires representative animal models to validate treatments before they are translated to human clinical trials.Rodents are the predominant animal model used in neurological research despite limited anatomic and physiologic similarities to humans.As a result,functional testing designed to assess locomotor recovery after neurologic impairment is well established in rodent models.Comparatively,large r,more clinically relevant models have not been as well studied.To achieve similar locomotor testing standardization in larger animals,the models must be accessible to a wide array of researchers.Non-human primates are the most relevant animal model fo r translational research,however ethical and financial barriers limit their accessibility.This review focuses on swine,sheep,and goats as large animal alternatives for transitional studies between rodents and non-human primates.The objective of this review is to compare motor testing and data collection methods used in swine,sheep,and goats to encourage testing standardization in these larger animal models.The PubMed database was analyzed by searching combinations of swine,sheep,and goats,neurologic injuries,and functional assessments.Findings were categorized by animal model,data collection method,and assessment design.Swine and sheep were used in the majority of the studies,while only two studies were found using goats.The functional assessments included open pen analysis,treadmill walking,and guided free walking.Data collection methods included subjective behavioral rating scales and objective tools such as pressure-sensitive mats and image-based analysis software.Overall,swine and sheep were well-suited for a variety of assessment designs,with treadmill walking and guided free walking offering the most consistency across multiple trials.Data collection methods varied,but image-based gait analysis software provided the most robust analysis.Future studies should be conducted to standardize functional testing methods after neurologic impairment in large animals.展开更多
The anterior cruciate ligament plays a crucial role in maintaining stability within the knee joint,particularly for athletes who frequently experience its rupture.This study presents a novel approach using personalize...The anterior cruciate ligament plays a crucial role in maintaining stability within the knee joint,particularly for athletes who frequently experience its rupture.This study presents a novel approach using personalized three-dimensional(3D)parametric finite element modeling of the knee joint to simulate the treatment following anterior cruciate ligament reconstruction(ACLR)in both forward walking(FW)and drop landing(DL)tasks.The study encompasses two distinct cohorts:five healthy athletes and five ACLR patients.Biomechanical motion analysis was conducted on both cohorts,with the ACLR patient group evaluated at 6 and 9 months post-surgery.A comprehensive 3D parametric model of the knee joint was meticulously crafted.The findings reveal a notable reduction in stress on crucial knee structures such as the autograft,meniscus,and cartilages over time for both FW and DL tasks following ACLR,with a reduction in tissue tension of approximately 9.5%and 37%for FW and DL,respectively.This personalized model not only facilitates the investigation of knee joint tissue biomechanics post-ACLR but also aids in estimating the return-to-sports timeline for patients.By accommodating individual tissue geometries and incorporating patient-specific kinetic data,this model enhances our comprehension of post-ACLR biomechanics across various functional tasks,thereby optimizing rehabilitation strategies.展开更多
Human Activity Recognition(HAR)has always been a difficult task to tackle.It is mainly used in security surveillance,human-computer interaction,and health care as an assistive or diagnostic technology in combination w...Human Activity Recognition(HAR)has always been a difficult task to tackle.It is mainly used in security surveillance,human-computer interaction,and health care as an assistive or diagnostic technology in combination with other technologies such as the Internet of Things(IoT).Human Activity Recognition data can be recorded with the help of sensors,images,or smartphones.Recognizing daily routine-based human activities such as walking,standing,sitting,etc.,could be a difficult statistical task to classify into categories and hence 2-dimensional Convolutional Neural Network(2D CNN)MODEL,Long Short Term Memory(LSTM)Model,Bidirectional long short-term memory(Bi-LSTM)are used for the classification.It has been demonstrated that recognizing the daily routine-based on human activities can be extremely accurate,with almost all activities accurately getting recognized over 90%of the time.Furthermore,because all the examples are generated from only 20 s of data,these actions can be recognised fast.Apart from classification,the work extended to verify and investigate the need for wearable sensing devices in individually walking patients with Cerebral Palsy(CP)for the evaluation of chosen Spatio-temporal features based on 3D foot trajectory.Case-control research was conducted with 35 persons with CP ranging in weight from 25 to 65 kg.Optical Motion Capture(OMC)equipment was used as the referral method to assess the functionality and quality of the foot-worn device.The average accuracy±precision for stride length,cadence,and step length was 3.5±4.3,4.1±3.8,and 0.6±2.7 cm respectively.For cadence,stride length,swing,and step length,people with CP had considerably high inter-stride variables.Foot-worn sensing devices made it easier to examine Gait Spatio-temporal data even without a laboratory set up with high accuracy and precision about gait abnormalities in people who have CP during linear walking.展开更多
It is still controversial whether or not to resurface patella during primary total knee arthroplasty (TKA).One of the reasons may be insensitive measurement tools.We conducted a randomized controlled study to compare ...It is still controversial whether or not to resurface patella during primary total knee arthroplasty (TKA).One of the reasons may be insensitive measurement tools.We conducted a randomized controlled study to compare kinematic and kinetic parameters of resurfacing and nonresurfacing patella with the Vicon gait analysis system.The results show that patient post-operative gait of the two groups improved compared to pre-operative gait.Part of gait parameters,knee flexion at heel-strike,double limb support time and maximum adduction angle appeared to be statistically difference in 3 months,but 12 months later,the gait parameters of the two groups had no significant difference.Therefore,it seems that the final function of knee after TKA is not related whether or not to resurface patella.展开更多
Individuals with autism spectrum disorder(ASD)often exhibit motor deficits that increase their risk of falls.There is a lack of understanding regarding gait biomechanics demonstrated by older children with ASD.The pur...Individuals with autism spectrum disorder(ASD)often exhibit motor deficits that increase their risk of falls.There is a lack of understanding regarding gait biomechanics demonstrated by older children with ASD.The purpose of the study was to determine differences in gait patterns between older children with ASD and typically developing children.Eleven children with ASD and 11 age-and gender-matched typically developing children were recruited for the study.Participants walked on a force-instrumented treadmill at a constant speed(1.1 m/s-1.2 m/s)for five minutes(min).Participants performed maximal voluntary contractions to assess their knee muscular strength.Differences between individuals with ASD and matched control participants were examined through paired t-tests with a significance level of p0.05.Individuals with ASD demonstrated a smaller knee extensor torque compared to controls(p=0.002).Participants with ASD exhibited a shorter stride length(p=0.04),a greater cadence(p=0.03),and a higher variation in stride width(p=0.04)compared to control participants.The individuals with ASD experienced a greater braking ground reaction force(p=0.03)during loading response.The results indicate older children with ASD develop a unique gait pattern signified by a reduced stride length,increased cadence,and an increase of variation in stride width.This unique gait pattern may represent a movement strategy used by the individuals with ASD to compensate for the weakness associated with their knee extensor muscles.Individuals with ASD who demonstrate these unique gait deviations may face reduced postural stability and an increased risk of fall-related injuries.展开更多
Parkinson’s disease is identified as one of the key neurodegenerative disorders occurring due to the damages present in the central nervous system.The cause of such brain damage seems to be fully explained in many res...Parkinson’s disease is identified as one of the key neurodegenerative disorders occurring due to the damages present in the central nervous system.The cause of such brain damage seems to be fully explained in many research studies,but the understanding of its functionality remains to be impractical.Specifically,the development of a quantitative disease prediction model has evolved in recent decades.Moreover,accelerometer sensor-based gait analysis is accepted as an important tool for recognizing the walking behavior of the patients during the early prediction and diagnosis of Parkinson’s disease.This type of minimal infrastructure equipment helps in analyzing the Parkinson’s gait properties without affecting the common behavioral patterns during the clinical practices.Therefore,the Accelerometer Sensor-based Parkinson’s Disease Identi-fication System(ASPDIS)is introduced with a kernel-based support vector machine classifier model to make an early prediction of the disease.consequently,the proposed classifier can easily predict various severity levels of Parkinson’s disease from the sensor data.The performance of the proposed classifier is com-pared against the existing models such as random forest,decision tree,and k-near-est neighbor classifiers respectively.As per the experimental observation,the proposed classifier has more capability to differentiate Parkinson’s from non-Parkinson patients depending upon the severity levels.Also,it is found that the model has outperformed the existing classifiers concerning prediction time and accuracy respectively.展开更多
[Objectives]To observe the effect of motor relearning combined with transcranial direct current stimulation on the motor function of lower extremities in patients with cerebral infarction,and to observe its effect on ...[Objectives]To observe the effect of motor relearning combined with transcranial direct current stimulation on the motor function of lower extremities in patients with cerebral infarction,and to observe its effect on gait by 3D gait analysis.[Methods]60 patients with cerebral infarction who met the inclusion criteria were randomly divided into 3 groups according to the order of treatment(n=20).Group A received motor relearning treatment,group B received transcranial direct current stimulation treatment,group C received motor relearning combined with transcranial direct current stimulation,and the curative effect was observed after 5 courses of treatment.[Results]Before treatment,FMA,MBI,spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,stride length,gait speed,stride length deviation,double support)and lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,maximum knee extension,stance phase,swing phase)were compared among the three groups.After treatment,the FMA and MBI of the three groups increased,and the spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,gait speed,double support)and the lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,swing phase)were all improved,while the spatio-temporal parameters(stride length and stride length deviation)and the lower limb joint motion parameters(maximum knee extension and stance phase)decreased.Compared with those before treatment,there were significant differences among the three groups(P<0.05).Through the comparison between groups,it was found that the FMA,MBI,spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,gait speed,double support)and lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,swing phase)in group C were significantly higher than those in group A and B,while the spatio-temporal parameters(stride length and stride length deviation)and lower limb joint motion parameters(maximum knee extension and stance phase)in group C were significantly lower than those in group A and group B,and the difference was statistically significant(P<0.05).[Conclusions]Motor relearning combined with transcranial direct current stimulation could increase MBI and FMA,improve gait spatio-temporal parameters and lower limb joint motion parameters,and correct abnormal gait in patients with cerebral infarction.展开更多
Gait is a key function of human movement which plays an important role in motion analysis. Both in the clinical field and in rehabilitation, gait analysis is useful to evaluate the parameters that are modified followi...Gait is a key function of human movement which plays an important role in motion analysis. Both in the clinical field and in rehabilitation, gait analysis is useful to evaluate the parameters that are modified following the administration of a protocol of adapted physical activity （APA）. Gait parameters could be measured using traditional rating scales, such as the Short Physical Performance Battery （SPPB） and technologies as a support to provide an assessment of gait quality. The aim of this study is to increase the objectivity of gait data obtained before and after a targeted APA program for a group of elderly people by integrating the traditional SPPB rating scale with the G Walk digital system. The former is an assessment tool to evaluate the functioning of lower extremity, in terms of chair stand, walk, and standing balance; whereas the latter can objectively evaluate the parameters of the gait. The sample was composed of I 1 adults aged between 67 and 94 years. The participants were chosen on the basis of a number of tests carried out to analyze their levels of autonomy, intellectual capacities and motor functioning. It has planned a six months APA protocol： before and after it, SPPB and G-Walk were administered. The results showed that space-time characteristics generally improve after APA intervention; therefore, the use of technology is a useful support for the evaluation scales.展开更多
The aim of the present study was to develop and validate a new marker model for optoelectronic systems adapted to wearable devices, in order to have an analysis tool for kinematic gait evaluation of reproduced pattern...The aim of the present study was to develop and validate a new marker model for optoelectronic systems adapted to wearable devices, in order to have an analysis tool for kinematic gait evaluation of reproduced patterns by exoskeletons. The marker model has a total of 36 retro-reflective markers attached bilaterally to anatomical landmarks during the static measures （without exoskeleton） and 28 markers at the dynamics measures （with exoskeleton）. The main difference between others kinematic models and the described adapted model was the placement of the three markers in the back thigh and the other three in the back calf, what allowed removing the hip, thigh, knee, tibia and ankle markers. The proposed adapted marker model could be an effective tool to validate the joint movement and velocities of those wearable exoskeletons that at present have been developing.展开更多
Purpose: This study focused on maintaining and improving the walking function of late-stage older individuals while longitudinally tracking the effects of regular exercise programs in a day-care service specialized fo...Purpose: This study focused on maintaining and improving the walking function of late-stage older individuals while longitudinally tracking the effects of regular exercise programs in a day-care service specialized for preventive care over 5 years, using detailed gait function measurements with an accelerometer-based system. Methods: Seventy individuals (17 male and 53 female) of a daycare service in Tokyo participated in a weekly exercise program, meeting 1 - 2 times. The average age of the participants at the start of the program was 81.4 years. Gait function, including gait speed, stride length, root mean square (RMS) of acceleration, gait cycle time and its standard deviation, and left-right difference in stance time, was evaluated every 6 months. Results: Gait speed and stride length improved considerably within six months of starting the exercise program, confirming an initial improvement in gait function. This suggests that regular exercise programs can maintain or improve gait function even age groups that predictably have a gradual decline in gait ability due to enhanced age. In the long term, many indicators tended to approach baseline values. However, the exercise program seemingly counteracts age-related changes in gait function and maintains a certain level of function. Conclusions: While a decline in gait ability with aging is inevitable, establishing appropriate exercise habits in late-stage older individuals may contribute to long-term maintenance of gait function.展开更多
Purpose: This study verified the effects of transcutaneous electrical nerve stimulation (TENS), which can be worn during walking and exercise, in elderly individuals with late-stage knee pain who exercise regularly. M...Purpose: This study verified the effects of transcutaneous electrical nerve stimulation (TENS), which can be worn during walking and exercise, in elderly individuals with late-stage knee pain who exercise regularly. Methods: Thirty-two late-stage elderly individuals were evaluated for knee pain during rest, walking, and program exercises, with and without TENS. Gait analysis was performed using an IoT-based gait analysis device to examine the effects of TENS-induced analgesia on gait. Results: TENS significantly reduced knee pain during rest, walking, and programmed exercises, with the greatest analgesic effect observed during walking. The greater the knee pain without TENS, the more significant the analgesic effect of TENS. A comparison of gait parameters revealed a significant difference only in the gait cycle time, with a trend towards faster walking with TENS;however, the effect was limited. Conclusion: TENS effectively relieves knee pain in late-stage elderly individuals and can be safely applied during exercise. Pain management using TENS provides important insights into the implementation of exercise therapy in this age group.展开更多
Objective:To observe the clinical efficacy of sitting-position knee adjustment Tuina(Chinese therapeutic massage)and therapeutic ultrasound in treating knee osteoarthritis(KOA)and the impact on gait analysis parameter...Objective:To observe the clinical efficacy of sitting-position knee adjustment Tuina(Chinese therapeutic massage)and therapeutic ultrasound in treating knee osteoarthritis(KOA)and the impact on gait analysis parameters.Methods:In a randomized controlled design,80 KOA patients were randomly allocated to a manipulation group and an ultrasound group,each with 40 cases.Patients in the manipulation group received the sitting-position knee adjustment Tuina treatment;patients in the ultrasound group received low-frequency ultrasounds for treatment.The intervention was conducted twice weekly,and therapeutic efficacy was evaluated after 4 weeks of treatment.Before treatment,immediately after treatment,and after 2-week and 4-week treatment,the visual analog scale(VAS)and the Western Ontario and McMaster Universities osteoarthritis index(WOMAC)scores were observed;the gait analysis outcomes were compared before treatment and after 4-week treatment,including cadence,speed,step length,stride length,single stance phase,double stance phase,and the maximal flexion angle of the knee joint.Results:Intra-group comparisons revealed that both groups showed decreased VAS scores and increased WOMAC scores immediately after treatment and after 2-week and 4-week treatment,with statistical significance(P<0.05).Immediately after treatment,the VAS score was lower in the manipulation group than in the ultrasound group(P<0.05),and the WOMAC pain score was higher in the manipulation group(P<0.05),while the ultrasound group had a higher WOMAC stiffness score than the manipulation group(P<0.05).After 2 weeks of treatment,there were no significant differences in VAS and WOMAC scores between the two groups(P>0.05).After 4-week treatment,the ultrasound group had a higher WOMAC pain score than the manipulation group(P<0.05),and the manipulation group had higher WOMAC stiffness and function scores than the ultrasound group(P<0.05).The between-group difference in the WOMAC total score remained statistically insignificant throughout the treatment(P>0.05).Regarding the gait parameters,both groups showed improvements in the cadence,speed,step length,stride length,single stance phase,double stance phase,swing phase,and maximal knee flexion angle immediately after treatment and after 2 and 4 weeks of treatment;the intra-group differences were all statistically significant(P<0.05).After 4-week treatment,the manipulation group surpassed the ultrasound group in improvements in stride length,step length,swing phase,single stance phase,and maximal knee flexion angle(P<0.05).Conclusion:Both the sitting-position knee adjustment Tuina and low-frequency ultrasound therapies are effective in treating KOA and can improve the patient’s walking ability;the sitting-position knee adjustment manipulation demonstrates superior immediate pain relief and long-term improvement of stiffness,joint function,and walking ability compared to the low-frequency ultrasound.展开更多
Objective:To observe the effect of acupuncture plus shock wave therapy on pain and dysfunction in patients with lumbar disc herniation(LDH),and to explore the feasibility of gait analysis for evaluating LDH symptoms b...Objective:To observe the effect of acupuncture plus shock wave therapy on pain and dysfunction in patients with lumbar disc herniation(LDH),and to explore the feasibility of gait analysis for evaluating LDH symptoms based on the gait real-time analysis interactive lab(GRAIL).Methods:A total of 67 patients with LDH were divided into two groups by the random number table method.Thirtythree cases in the observation group received acupuncture plus shock wave therapy,and 34 cases in the control group were treated with shock wave therapy alone.The step length and walk velocity based on GRAIL,and the scores of visual analog scale(VAS),Osweatry disability index(ODI),and Japanese Orthopaedie Association(JOA)were observed before and after treatment.The data differences between before and after treatment and their correlation were analyzed.Results:After treatment,the step length,walk velocity,and the scores of VAS,ODI,and JOA in both groups were statistically different from those before treatment(P<0.01).The step length,walk velocity,and JOA score in the observation group were higher than those in the control group,while the VAS and ODI scores were lower than those in the control group;the differences between the two groups were all statistically significant(P<0.05).The step length was negatively correlated with the VAS and ODI scores,and positively correlated with the JOA score(P<0.05).The improvement of step length was positively correlated with the improvement of VAS,ODI,and JOA scores(P<0.05).Conclusion:Compared with shock wave therapy alone,acupuncture combined with shock wave therapy has more advantages in improving the step length and walk velocity,and reducing pain and dysfunction in LDH patients.The results of GRAIL-based gait analysis can be used as a potential indicator for evaluating the therapeutic effect in the treatment of LDH.展开更多
[Objectives]To investigate the clinical efficacy of acupoint injection of nerve growth factors combined with task-oriented training for patients with post-stroke hemiplegic gait,and quantitatively evaluate the outcome...[Objectives]To investigate the clinical efficacy of acupoint injection of nerve growth factors combined with task-oriented training for patients with post-stroke hemiplegic gait,and quantitatively evaluate the outcomes using the Gait Watch analysis system.[Methods]A total of 90 patients with post-stroke hemiplegia,who were hospitalized at the Rehabilitation Center of Taihe Hospital between January 2023 and December 2023,were selected for this study.The participants were randomly assigned to three groups:the task-oriented rehabilitation training group(control group I,n=30),the ordinary acupuncture combined with task-oriented training group(control group II,n=30),and the acupoint injection combined with task-oriented training group(observation group,n=30).Each group underwent treatment for 4 weeks.The Gait Watch analysis system was employed to assess the spatiotemporal gait parameters of the patients prior to treatment,as well as 2 weeks post treatment and 4 weeks post treatment.The efficacy of the treatment was subsequently analyzed.[Results]After 4 weeks of treatment,the spatiotemporal gait parameters,specifically step length,step speed,step frequency,percentage of the standing phase,and percentage of the swinging phase,exhibited significant improvement in the observation group compared to those before treatment(P<0.05).Furthermore,the degree of improvement in the observation group was superior to that observed in both control group I and control group II,with the differences reaching statistical significance(P<0.05).[Conclusions]Acupoint injection combined with task-oriented training has been shown to significantly enhance gait function in patients with post-stroke hemiplegia.The Gait Watch analysis system offers an accurate and objective quantitative assessment,making it a valuable tool for clinical application and promotion.展开更多
Gait analysis is an important method for studying the laws and characteristics of human motion.With the wide application of Artificial Neural Networks(ANN)in various fields,their value in gait analysis has become incr...Gait analysis is an important method for studying the laws and characteristics of human motion.With the wide application of Artificial Neural Networks(ANN)in various fields,their value in gait analysis has become increasingly prominent.This paper systematically reviews the application of ANN in the analysis of gait kinematics,dynamics,and spatiotemporal parameters,and deeply discusses the main existing problems,such as model construction,training data,and limitations of single perspective.It also looks forward to the future development directions.Future research should focus on developing more accurate network models,integrating multimodal training methods,and constructing datasets with unified standards to promote the wide application of this technology in clinical practice and sports science.展开更多
Purpose:To observe the changes of gait behavior and the expression of wound healing factors of transforming growth factor-β1(TGF-β1),TGF-β3 and cAMP response element binding protein-1(CREB-1)during the healing of A...Purpose:To observe the changes of gait behavior and the expression of wound healing factors of transforming growth factor-β1(TGF-β1),TGF-β3 and cAMP response element binding protein-1(CREB-1)during the healing of Achilles tendon in a rat model,and to investigate whether gait analysis can be used to evaluate the tendon healing.Methods:Achilles tendon of 40 healthy male Sprague-Dawley rats were transected and sutured to establish the Achilles tendon injury(ATI)model.They were randomly divided into 4 groups based on the observational time point at 1,2,4 and 6 weeks after injury(n=10 for each group).Before modeling,9 rats were randomly selected for CatWalk gait analysis,which contained step cycle,single stance time and average speed.Data were recorded as the normal controls.After then,ATI models were established in the left hind limbs of the all 40 rats(ATI group),while the right hind limbs were only cut and sutured without injury of the Achilles tendon(sham operation group).At 1,2,4 and 6 weeks after injury,the gait behavior of the corresponding group of rats(n=9)as observed and recorded by CatWalk platform.After then,the rats were sacrificed and Achilles tendon of both limbs was harvested.The tendon healing was observed by gross anatomy and histological examination,and the protein and mRNA expression of TGF-β1,TGF-β3,CREB-1 were observed by immunohistochemistry and qPCR.The results of tendon gross grading were analyzed by Wilcoxon rank sum test,and other data were analyzed by one-way analysis of variance among multiple groups.Results:Compared with normal controls,all gait indexes(step cycle,single stance time and average speed)were greatly affected following ATI,which however improved with time.The step cycle was significantly lower at 1,2 and 4 weeks after ATI(compared with normal controls,allp<0.05),but almost returned to the normal level at 6 weeks((0.694±0.102)vs.(0.503±0.094)s,p>0.05).The single stance time of the ATI group was significantly shorter at 1 and 2 weeks after operation((0.078±0.010)s at 1 week,(0.078±0.020)s at 2 weeks,allp<0.001)and revealed no significant difference at 4 weeks(p=0.120).The average speed of ATI group at 1,2,4,6 weeks was significantly lower than that in the normal control group(allp<0.001).Conclusion:Gait behavior indexes are associated with Achilles tendon healing.The study gives an insight of TGF-β1,TGF-β3,CREB-1 changes in the coursing of Achilles tendon healing and these cytokines may be able to be used to regulate the Achilles tendon healing.展开更多
基金the National Traditional Chinese Medicine Inheritance and Innovation Team Project:Traditional Chinese Medicine Innovation Team for Prevention and Treatment of Bone and Joint Degenerative Diseases (No. ZYYCXTD-C-202003)National Natural Science Foundation of China:the study on the Quantification and Mechanism of the rotating-pulling-poking manipulation in the Treatment of Lateral Ankle Sprain (No. 81473694)China Academy of Chinese Medical Sciences Science and Technology Innovation Project:Establishment and Promotion of a Simulation Operation Evaluation System for Rotating-pulling-poking Manipulation (CI2021A02015)。
文摘OBJECTIVE:To compare the changes in gait parameters before and after the treatment of lateral ankle sprain using the rotating-pulling-poking manipulation, and explore the potential bio-mechanical mechanism of this manipulation. METHODS:Forty patients with lateral ankle sprains were randomly divided into two groups in a 1∶1 ratio using a random number table. The experimental group were treated by rotating-pulling-poking manipulation and elastic bandage external fixation, while the control group were treated by ice compress and elastic bandage external fixation. The treatment courses of the two groups were both 2 weeks. We used a three-dimensional motion capture system for kinematic measurements and a Bertec gait analysis force measurement system for mechanical measurements, and compared the changes in gait parameters between the two groups of patients before and after treatment. RESULTS:Intragroup comparison showed that the support time, swing time, peak of back extension, peak of plantar flexion, peak of toe pedal force, and peak of heel landing force of the affected feet in the experimental group were significantly improved compared to those before treatment(P < 0.05). The swing time of the affected feet in the control group was significantly improved compared to that before treatment(P < 0.05). The inter group comparison showed that the gait speed, stride length, peak of back extension, peak of plantar flexion, peak of toe pedal force, and peak of heel landing force of the affected feet in the experimental group were significantly better than those in the control group(P < 0.05). CONCLUSIONS:The rotating-pulling-poking manipulation can effectively improve the patient's gait and range of motion of the affected ankle joint, and enhance the negative gravity in the vertical direction of the affected foot, and the braking and driving forces in the front and back directions. This may be the potential biomechanical mechanism of the rotating-pulling-poking manipulation for treating lateral ankle sprain.
基金provided by the Educational Bureau of Liaoning Province,No. 2009A671
文摘An experiment was carried out in the key laboratory for Technique Diagnosis and Function Assessment of Winter Sports of China to investigate the differences in gait characteristics between healthy children and children with spastic hemiplegic cerebral palsy. With permission of their parents, 200 healthy children aged 3 to 6 years in the kindergarten of Northeastern University were enrolled in this experiment. Twenty children aged 3 to 6 years with spastic hemiplegic cerebral palsy from Shengjing Hospital, China were also enrolled in this experiment. Standard data were collected by simultaneously recording gait information from two digital cameras. DVracker was used to analyze the standard data. The children with hemiplegic cerebra palsy had a longer gait cycle, slower walking speed, and longer support phase than did the healthy children. The support phase was longer than the swing phase in the children with hemiplegic cerebral palsy. There were significant differences in the angles of the hip, knee, and ankle joint between children with cerebral palsy and healthy children at the moment of touching the ground and buffering, and during pedal extension. Children with hemiplegic cerebral palsy had poor motor coordination during walking, which basically resulted in a short stride, high stride frequency to maintain speed, more obvious swing, and poor stability.
文摘Assessment of locomotion recovery in preclinical studies of experimental spinal cord injury remains challenging. We studied the CatWalk XT■gait analysis for evaluating hindlimb functional recovery in a widely used and clinically relevant thoracic contusion/compression spinal cord injury model in rats. Rats were randomly assigned to either a T9 spinal cord injury or sham laminectomy. Locomotion recovery was assessed using the Basso, Beattie, and Bresnahan open field rating scale and the CatWalk XT■gait analysis. To determine the potential bias from weight changes, corrected hindlimb(H) values(divided by the unaffected forelimb(F) values) were calculated. Six weeks after injury, cyst formation, astrogliosis, and the deposition of chondroitin sulfate glycosaminoglycans were assessed by immunohistochemistry staining. Compared with the baseline, a significant spontaneous recovery could be observed in the CatWalk XT■parameters max intensity, mean intensity, max intensity at%, and max contact mean intensity from 4 weeks after injury onwards. Of note, corrected values(H/F) of CatWalk XT■parameters showed a significantly less vulnerability to the weight changes than absolute values, specifically in static parameters. The corrected CatWalk XT■parameters were positively correlated with the Basso, Beattie, and Bresnahan rating scale scores, cyst formation, the immunointensity of astrogliosis and chondroitin sulfate glycosaminoglycan deposition. The CatWalk XT■gait analysis and especially its static parameters, therefore, seem to be highly useful in assessing spontaneous recovery of hindlimb function after severe thoracic spinal cord injury. Because many CatWalk XT■parameters of the hindlimbs seem to be affected by body weight changes, using their corrected values might be a valuable option to improve this dependency.
文摘AIM To describe,using gait analysis,the development of spinal motion in the growing child.METHODS Thirty-six healthy children aged from 3 to 16 years old were included in this study for a gait analysis(9m-walk).Various kinematic parameters were recorded and analyzed such as thoracic angle(TA),lumbar angle(LA)and sagittal vertical axis(SVA).The kinetic parameters were the net reaction moments(N.m/kg)at the thoracolumbar and lumbosacral junctions.RESULTS TA and LA curves were not statistically correlated to the age(respectively,P=0.32 and P=0.41).SVA increased significantly with age(P<0.001).Moments in sagittal plane at the lumbosacral junction were statistically correlated to the age(P=0.003),underlining the fact that sagittal mechanical constraints at the lumbosacral junction increase with age.Moments in transversal plane at the thoracolumbar and lumbosacral junctions were statistically correlated to the age(P=0.0002and P=0.0006),revealing that transversal mechanical constraints decrease with age.CONCLUSION The kinetic analysis showed that during growth,a decrease of torsional constraint occurs while an increase of sagittal constraint is observed.These changes in spine biomechanics are related to the crucial role of the trunk for bipedalism acquisition,allowing stabilization despite lower limbs immaturity.With the acquisition of mature gait,the spine will mainly undergo constraints in the sagittal plane.
文摘Medical research on neurologic ailments requires representative animal models to validate treatments before they are translated to human clinical trials.Rodents are the predominant animal model used in neurological research despite limited anatomic and physiologic similarities to humans.As a result,functional testing designed to assess locomotor recovery after neurologic impairment is well established in rodent models.Comparatively,large r,more clinically relevant models have not been as well studied.To achieve similar locomotor testing standardization in larger animals,the models must be accessible to a wide array of researchers.Non-human primates are the most relevant animal model fo r translational research,however ethical and financial barriers limit their accessibility.This review focuses on swine,sheep,and goats as large animal alternatives for transitional studies between rodents and non-human primates.The objective of this review is to compare motor testing and data collection methods used in swine,sheep,and goats to encourage testing standardization in these larger animal models.The PubMed database was analyzed by searching combinations of swine,sheep,and goats,neurologic injuries,and functional assessments.Findings were categorized by animal model,data collection method,and assessment design.Swine and sheep were used in the majority of the studies,while only two studies were found using goats.The functional assessments included open pen analysis,treadmill walking,and guided free walking.Data collection methods included subjective behavioral rating scales and objective tools such as pressure-sensitive mats and image-based analysis software.Overall,swine and sheep were well-suited for a variety of assessment designs,with treadmill walking and guided free walking offering the most consistency across multiple trials.Data collection methods varied,but image-based gait analysis software provided the most robust analysis.Future studies should be conducted to standardize functional testing methods after neurologic impairment in large animals.
文摘The anterior cruciate ligament plays a crucial role in maintaining stability within the knee joint,particularly for athletes who frequently experience its rupture.This study presents a novel approach using personalized three-dimensional(3D)parametric finite element modeling of the knee joint to simulate the treatment following anterior cruciate ligament reconstruction(ACLR)in both forward walking(FW)and drop landing(DL)tasks.The study encompasses two distinct cohorts:five healthy athletes and five ACLR patients.Biomechanical motion analysis was conducted on both cohorts,with the ACLR patient group evaluated at 6 and 9 months post-surgery.A comprehensive 3D parametric model of the knee joint was meticulously crafted.The findings reveal a notable reduction in stress on crucial knee structures such as the autograft,meniscus,and cartilages over time for both FW and DL tasks following ACLR,with a reduction in tissue tension of approximately 9.5%and 37%for FW and DL,respectively.This personalized model not only facilitates the investigation of knee joint tissue biomechanics post-ACLR but also aids in estimating the return-to-sports timeline for patients.By accommodating individual tissue geometries and incorporating patient-specific kinetic data,this model enhances our comprehension of post-ACLR biomechanics across various functional tasks,thereby optimizing rehabilitation strategies.
文摘Human Activity Recognition(HAR)has always been a difficult task to tackle.It is mainly used in security surveillance,human-computer interaction,and health care as an assistive or diagnostic technology in combination with other technologies such as the Internet of Things(IoT).Human Activity Recognition data can be recorded with the help of sensors,images,or smartphones.Recognizing daily routine-based human activities such as walking,standing,sitting,etc.,could be a difficult statistical task to classify into categories and hence 2-dimensional Convolutional Neural Network(2D CNN)MODEL,Long Short Term Memory(LSTM)Model,Bidirectional long short-term memory(Bi-LSTM)are used for the classification.It has been demonstrated that recognizing the daily routine-based on human activities can be extremely accurate,with almost all activities accurately getting recognized over 90%of the time.Furthermore,because all the examples are generated from only 20 s of data,these actions can be recognised fast.Apart from classification,the work extended to verify and investigate the need for wearable sensing devices in individually walking patients with Cerebral Palsy(CP)for the evaluation of chosen Spatio-temporal features based on 3D foot trajectory.Case-control research was conducted with 35 persons with CP ranging in weight from 25 to 65 kg.Optical Motion Capture(OMC)equipment was used as the referral method to assess the functionality and quality of the foot-worn device.The average accuracy±precision for stride length,cadence,and step length was 3.5±4.3,4.1±3.8,and 0.6±2.7 cm respectively.For cadence,stride length,swing,and step length,people with CP had considerably high inter-stride variables.Foot-worn sensing devices made it easier to examine Gait Spatio-temporal data even without a laboratory set up with high accuracy and precision about gait abnormalities in people who have CP during linear walking.
文摘It is still controversial whether or not to resurface patella during primary total knee arthroplasty (TKA).One of the reasons may be insensitive measurement tools.We conducted a randomized controlled study to compare kinematic and kinetic parameters of resurfacing and nonresurfacing patella with the Vicon gait analysis system.The results show that patient post-operative gait of the two groups improved compared to pre-operative gait.Part of gait parameters,knee flexion at heel-strike,double limb support time and maximum adduction angle appeared to be statistically difference in 3 months,but 12 months later,the gait parameters of the two groups had no significant difference.Therefore,it seems that the final function of knee after TKA is not related whether or not to resurface patella.
文摘Individuals with autism spectrum disorder(ASD)often exhibit motor deficits that increase their risk of falls.There is a lack of understanding regarding gait biomechanics demonstrated by older children with ASD.The purpose of the study was to determine differences in gait patterns between older children with ASD and typically developing children.Eleven children with ASD and 11 age-and gender-matched typically developing children were recruited for the study.Participants walked on a force-instrumented treadmill at a constant speed(1.1 m/s-1.2 m/s)for five minutes(min).Participants performed maximal voluntary contractions to assess their knee muscular strength.Differences between individuals with ASD and matched control participants were examined through paired t-tests with a significance level of p0.05.Individuals with ASD demonstrated a smaller knee extensor torque compared to controls(p=0.002).Participants with ASD exhibited a shorter stride length(p=0.04),a greater cadence(p=0.03),and a higher variation in stride width(p=0.04)compared to control participants.The individuals with ASD experienced a greater braking ground reaction force(p=0.03)during loading response.The results indicate older children with ASD develop a unique gait pattern signified by a reduced stride length,increased cadence,and an increase of variation in stride width.This unique gait pattern may represent a movement strategy used by the individuals with ASD to compensate for the weakness associated with their knee extensor muscles.Individuals with ASD who demonstrate these unique gait deviations may face reduced postural stability and an increased risk of fall-related injuries.
文摘Parkinson’s disease is identified as one of the key neurodegenerative disorders occurring due to the damages present in the central nervous system.The cause of such brain damage seems to be fully explained in many research studies,but the understanding of its functionality remains to be impractical.Specifically,the development of a quantitative disease prediction model has evolved in recent decades.Moreover,accelerometer sensor-based gait analysis is accepted as an important tool for recognizing the walking behavior of the patients during the early prediction and diagnosis of Parkinson’s disease.This type of minimal infrastructure equipment helps in analyzing the Parkinson’s gait properties without affecting the common behavioral patterns during the clinical practices.Therefore,the Accelerometer Sensor-based Parkinson’s Disease Identi-fication System(ASPDIS)is introduced with a kernel-based support vector machine classifier model to make an early prediction of the disease.consequently,the proposed classifier can easily predict various severity levels of Parkinson’s disease from the sensor data.The performance of the proposed classifier is com-pared against the existing models such as random forest,decision tree,and k-near-est neighbor classifiers respectively.As per the experimental observation,the proposed classifier has more capability to differentiate Parkinson’s from non-Parkinson patients depending upon the severity levels.Also,it is found that the model has outperformed the existing classifiers concerning prediction time and accuracy respectively.
基金Supported by Scientific Research Project of Chinese Medicine of Hubei Provincial Health Commission(ZY2021Q015)Project of Taihe Hospital(2021JJXM077,2019JJXM099,2016JJXM023)。
文摘[Objectives]To observe the effect of motor relearning combined with transcranial direct current stimulation on the motor function of lower extremities in patients with cerebral infarction,and to observe its effect on gait by 3D gait analysis.[Methods]60 patients with cerebral infarction who met the inclusion criteria were randomly divided into 3 groups according to the order of treatment(n=20).Group A received motor relearning treatment,group B received transcranial direct current stimulation treatment,group C received motor relearning combined with transcranial direct current stimulation,and the curative effect was observed after 5 courses of treatment.[Results]Before treatment,FMA,MBI,spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,stride length,gait speed,stride length deviation,double support)and lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,maximum knee extension,stance phase,swing phase)were compared among the three groups.After treatment,the FMA and MBI of the three groups increased,and the spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,gait speed,double support)and the lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,swing phase)were all improved,while the spatio-temporal parameters(stride length and stride length deviation)and the lower limb joint motion parameters(maximum knee extension and stance phase)decreased.Compared with those before treatment,there were significant differences among the three groups(P<0.05).Through the comparison between groups,it was found that the FMA,MBI,spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,gait speed,double support)and lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,swing phase)in group C were significantly higher than those in group A and B,while the spatio-temporal parameters(stride length and stride length deviation)and lower limb joint motion parameters(maximum knee extension and stance phase)in group C were significantly lower than those in group A and group B,and the difference was statistically significant(P<0.05).[Conclusions]Motor relearning combined with transcranial direct current stimulation could increase MBI and FMA,improve gait spatio-temporal parameters and lower limb joint motion parameters,and correct abnormal gait in patients with cerebral infarction.
文摘Gait is a key function of human movement which plays an important role in motion analysis. Both in the clinical field and in rehabilitation, gait analysis is useful to evaluate the parameters that are modified following the administration of a protocol of adapted physical activity （APA）. Gait parameters could be measured using traditional rating scales, such as the Short Physical Performance Battery （SPPB） and technologies as a support to provide an assessment of gait quality. The aim of this study is to increase the objectivity of gait data obtained before and after a targeted APA program for a group of elderly people by integrating the traditional SPPB rating scale with the G Walk digital system. The former is an assessment tool to evaluate the functioning of lower extremity, in terms of chair stand, walk, and standing balance; whereas the latter can objectively evaluate the parameters of the gait. The sample was composed of I 1 adults aged between 67 and 94 years. The participants were chosen on the basis of a number of tests carried out to analyze their levels of autonomy, intellectual capacities and motor functioning. It has planned a six months APA protocol： before and after it, SPPB and G-Walk were administered. The results showed that space-time characteristics generally improve after APA intervention; therefore, the use of technology is a useful support for the evaluation scales.
文摘The aim of the present study was to develop and validate a new marker model for optoelectronic systems adapted to wearable devices, in order to have an analysis tool for kinematic gait evaluation of reproduced patterns by exoskeletons. The marker model has a total of 36 retro-reflective markers attached bilaterally to anatomical landmarks during the static measures （without exoskeleton） and 28 markers at the dynamics measures （with exoskeleton）. The main difference between others kinematic models and the described adapted model was the placement of the three markers in the back thigh and the other three in the back calf, what allowed removing the hip, thigh, knee, tibia and ankle markers. The proposed adapted marker model could be an effective tool to validate the joint movement and velocities of those wearable exoskeletons that at present have been developing.
文摘Purpose: This study focused on maintaining and improving the walking function of late-stage older individuals while longitudinally tracking the effects of regular exercise programs in a day-care service specialized for preventive care over 5 years, using detailed gait function measurements with an accelerometer-based system. Methods: Seventy individuals (17 male and 53 female) of a daycare service in Tokyo participated in a weekly exercise program, meeting 1 - 2 times. The average age of the participants at the start of the program was 81.4 years. Gait function, including gait speed, stride length, root mean square (RMS) of acceleration, gait cycle time and its standard deviation, and left-right difference in stance time, was evaluated every 6 months. Results: Gait speed and stride length improved considerably within six months of starting the exercise program, confirming an initial improvement in gait function. This suggests that regular exercise programs can maintain or improve gait function even age groups that predictably have a gradual decline in gait ability due to enhanced age. In the long term, many indicators tended to approach baseline values. However, the exercise program seemingly counteracts age-related changes in gait function and maintains a certain level of function. Conclusions: While a decline in gait ability with aging is inevitable, establishing appropriate exercise habits in late-stage older individuals may contribute to long-term maintenance of gait function.
文摘Purpose: This study verified the effects of transcutaneous electrical nerve stimulation (TENS), which can be worn during walking and exercise, in elderly individuals with late-stage knee pain who exercise regularly. Methods: Thirty-two late-stage elderly individuals were evaluated for knee pain during rest, walking, and program exercises, with and without TENS. Gait analysis was performed using an IoT-based gait analysis device to examine the effects of TENS-induced analgesia on gait. Results: TENS significantly reduced knee pain during rest, walking, and programmed exercises, with the greatest analgesic effect observed during walking. The greater the knee pain without TENS, the more significant the analgesic effect of TENS. A comparison of gait parameters revealed a significant difference only in the gait cycle time, with a trend towards faster walking with TENS;however, the effect was limited. Conclusion: TENS effectively relieves knee pain in late-stage elderly individuals and can be safely applied during exercise. Pain management using TENS provides important insights into the implementation of exercise therapy in this age group.
文摘Objective:To observe the clinical efficacy of sitting-position knee adjustment Tuina(Chinese therapeutic massage)and therapeutic ultrasound in treating knee osteoarthritis(KOA)and the impact on gait analysis parameters.Methods:In a randomized controlled design,80 KOA patients were randomly allocated to a manipulation group and an ultrasound group,each with 40 cases.Patients in the manipulation group received the sitting-position knee adjustment Tuina treatment;patients in the ultrasound group received low-frequency ultrasounds for treatment.The intervention was conducted twice weekly,and therapeutic efficacy was evaluated after 4 weeks of treatment.Before treatment,immediately after treatment,and after 2-week and 4-week treatment,the visual analog scale(VAS)and the Western Ontario and McMaster Universities osteoarthritis index(WOMAC)scores were observed;the gait analysis outcomes were compared before treatment and after 4-week treatment,including cadence,speed,step length,stride length,single stance phase,double stance phase,and the maximal flexion angle of the knee joint.Results:Intra-group comparisons revealed that both groups showed decreased VAS scores and increased WOMAC scores immediately after treatment and after 2-week and 4-week treatment,with statistical significance(P<0.05).Immediately after treatment,the VAS score was lower in the manipulation group than in the ultrasound group(P<0.05),and the WOMAC pain score was higher in the manipulation group(P<0.05),while the ultrasound group had a higher WOMAC stiffness score than the manipulation group(P<0.05).After 2 weeks of treatment,there were no significant differences in VAS and WOMAC scores between the two groups(P>0.05).After 4-week treatment,the ultrasound group had a higher WOMAC pain score than the manipulation group(P<0.05),and the manipulation group had higher WOMAC stiffness and function scores than the ultrasound group(P<0.05).The between-group difference in the WOMAC total score remained statistically insignificant throughout the treatment(P>0.05).Regarding the gait parameters,both groups showed improvements in the cadence,speed,step length,stride length,single stance phase,double stance phase,swing phase,and maximal knee flexion angle immediately after treatment and after 2 and 4 weeks of treatment;the intra-group differences were all statistically significant(P<0.05).After 4-week treatment,the manipulation group surpassed the ultrasound group in improvements in stride length,step length,swing phase,single stance phase,and maximal knee flexion angle(P<0.05).Conclusion:Both the sitting-position knee adjustment Tuina and low-frequency ultrasound therapies are effective in treating KOA and can improve the patient’s walking ability;the sitting-position knee adjustment manipulation demonstrates superior immediate pain relief and long-term improvement of stiffness,joint function,and walking ability compared to the low-frequency ultrasound.
基金supported by Shanghai Sports Science and Technology Project(上海市体育科技项目,No.25J008)Shanghai Sailing Program(上海市“科技创新行动计划”启明星培育扬帆专项,No.24YF2747100)the Translational Medicine Research Project of Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine(上海中医药大学附属岳阳中西医结合医院转化医学研究项目,No.2024yyzh06).
文摘Objective:To observe the effect of acupuncture plus shock wave therapy on pain and dysfunction in patients with lumbar disc herniation(LDH),and to explore the feasibility of gait analysis for evaluating LDH symptoms based on the gait real-time analysis interactive lab(GRAIL).Methods:A total of 67 patients with LDH were divided into two groups by the random number table method.Thirtythree cases in the observation group received acupuncture plus shock wave therapy,and 34 cases in the control group were treated with shock wave therapy alone.The step length and walk velocity based on GRAIL,and the scores of visual analog scale(VAS),Osweatry disability index(ODI),and Japanese Orthopaedie Association(JOA)were observed before and after treatment.The data differences between before and after treatment and their correlation were analyzed.Results:After treatment,the step length,walk velocity,and the scores of VAS,ODI,and JOA in both groups were statistically different from those before treatment(P<0.01).The step length,walk velocity,and JOA score in the observation group were higher than those in the control group,while the VAS and ODI scores were lower than those in the control group;the differences between the two groups were all statistically significant(P<0.05).The step length was negatively correlated with the VAS and ODI scores,and positively correlated with the JOA score(P<0.05).The improvement of step length was positively correlated with the improvement of VAS,ODI,and JOA scores(P<0.05).Conclusion:Compared with shock wave therapy alone,acupuncture combined with shock wave therapy has more advantages in improving the step length and walk velocity,and reducing pain and dysfunction in LDH patients.The results of GRAIL-based gait analysis can be used as a potential indicator for evaluating the therapeutic effect in the treatment of LDH.
基金Supported by Hospital-level Project of Shiyan Taihe Hospital(2019JJXM117).
文摘[Objectives]To investigate the clinical efficacy of acupoint injection of nerve growth factors combined with task-oriented training for patients with post-stroke hemiplegic gait,and quantitatively evaluate the outcomes using the Gait Watch analysis system.[Methods]A total of 90 patients with post-stroke hemiplegia,who were hospitalized at the Rehabilitation Center of Taihe Hospital between January 2023 and December 2023,were selected for this study.The participants were randomly assigned to three groups:the task-oriented rehabilitation training group(control group I,n=30),the ordinary acupuncture combined with task-oriented training group(control group II,n=30),and the acupoint injection combined with task-oriented training group(observation group,n=30).Each group underwent treatment for 4 weeks.The Gait Watch analysis system was employed to assess the spatiotemporal gait parameters of the patients prior to treatment,as well as 2 weeks post treatment and 4 weeks post treatment.The efficacy of the treatment was subsequently analyzed.[Results]After 4 weeks of treatment,the spatiotemporal gait parameters,specifically step length,step speed,step frequency,percentage of the standing phase,and percentage of the swinging phase,exhibited significant improvement in the observation group compared to those before treatment(P<0.05).Furthermore,the degree of improvement in the observation group was superior to that observed in both control group I and control group II,with the differences reaching statistical significance(P<0.05).[Conclusions]Acupoint injection combined with task-oriented training has been shown to significantly enhance gait function in patients with post-stroke hemiplegia.The Gait Watch analysis system offers an accurate and objective quantitative assessment,making it a valuable tool for clinical application and promotion.
文摘Gait analysis is an important method for studying the laws and characteristics of human motion.With the wide application of Artificial Neural Networks(ANN)in various fields,their value in gait analysis has become increasingly prominent.This paper systematically reviews the application of ANN in the analysis of gait kinematics,dynamics,and spatiotemporal parameters,and deeply discusses the main existing problems,such as model construction,training data,and limitations of single perspective.It also looks forward to the future development directions.Future research should focus on developing more accurate network models,integrating multimodal training methods,and constructing datasets with unified standards to promote the wide application of this technology in clinical practice and sports science.
基金The National Natural Science Foundation of China(NO.81772330)Key Talents Support Project of Army Medical University(NO.B-3261)。
文摘Purpose:To observe the changes of gait behavior and the expression of wound healing factors of transforming growth factor-β1(TGF-β1),TGF-β3 and cAMP response element binding protein-1(CREB-1)during the healing of Achilles tendon in a rat model,and to investigate whether gait analysis can be used to evaluate the tendon healing.Methods:Achilles tendon of 40 healthy male Sprague-Dawley rats were transected and sutured to establish the Achilles tendon injury(ATI)model.They were randomly divided into 4 groups based on the observational time point at 1,2,4 and 6 weeks after injury(n=10 for each group).Before modeling,9 rats were randomly selected for CatWalk gait analysis,which contained step cycle,single stance time and average speed.Data were recorded as the normal controls.After then,ATI models were established in the left hind limbs of the all 40 rats(ATI group),while the right hind limbs were only cut and sutured without injury of the Achilles tendon(sham operation group).At 1,2,4 and 6 weeks after injury,the gait behavior of the corresponding group of rats(n=9)as observed and recorded by CatWalk platform.After then,the rats were sacrificed and Achilles tendon of both limbs was harvested.The tendon healing was observed by gross anatomy and histological examination,and the protein and mRNA expression of TGF-β1,TGF-β3,CREB-1 were observed by immunohistochemistry and qPCR.The results of tendon gross grading were analyzed by Wilcoxon rank sum test,and other data were analyzed by one-way analysis of variance among multiple groups.Results:Compared with normal controls,all gait indexes(step cycle,single stance time and average speed)were greatly affected following ATI,which however improved with time.The step cycle was significantly lower at 1,2 and 4 weeks after ATI(compared with normal controls,allp<0.05),but almost returned to the normal level at 6 weeks((0.694±0.102)vs.(0.503±0.094)s,p>0.05).The single stance time of the ATI group was significantly shorter at 1 and 2 weeks after operation((0.078±0.010)s at 1 week,(0.078±0.020)s at 2 weeks,allp<0.001)and revealed no significant difference at 4 weeks(p=0.120).The average speed of ATI group at 1,2,4,6 weeks was significantly lower than that in the normal control group(allp<0.001).Conclusion:Gait behavior indexes are associated with Achilles tendon healing.The study gives an insight of TGF-β1,TGF-β3,CREB-1 changes in the coursing of Achilles tendon healing and these cytokines may be able to be used to regulate the Achilles tendon healing.
