移动应用是近10年来兴起的新型计算模式,深刻地影响人民的生活方式.移动应用主要以图形用户界面(graphical user interface,GUI)方式交互,而对其进行人工测试需要消耗大量人力和物力.为此,研究者提出针对移动应用GUI的测试自动生成技术...移动应用是近10年来兴起的新型计算模式,深刻地影响人民的生活方式.移动应用主要以图形用户界面(graphical user interface,GUI)方式交互,而对其进行人工测试需要消耗大量人力和物力.为此,研究者提出针对移动应用GUI的测试自动生成技术以提升测试效率并检测潜在缺陷.收集了145篇相关论文,系统地梳理、分析和总结现有工作.提出了“测试生成器-测试环境”研究框架,将该领域的研究按照所属模块进行分类.特别地,依据测试生成器所基于的方法,将现有方法大致分为基于随机、基于启发式搜索、基于模型、基于机器学习和基于测试迁移这5个类别.此外,还从缺陷类别和测试动作等其他分类维度梳理现有方法.收集了该领域中较有影响力的数据集和开源工具.最后,总结当前面临的挑战并展望未来的研究方向.展开更多
Radiation-induced acoustic computed tomography(RACT)is an evolving biomedical imaging modality that aims to reconstruct the radiation energy deposition in tissues.Traditional backprojection(BP)reconstructions carry no...Radiation-induced acoustic computed tomography(RACT)is an evolving biomedical imaging modality that aims to reconstruct the radiation energy deposition in tissues.Traditional backprojection(BP)reconstructions carry noisy and limited-view artifacts.Model-based algorithms have been demonstrated to overcome the drawbacks of BPs.However,model-based algorithms are relatively more complex to develop and computationally demanding.Furthermore,while a plethora of novel algorithms has been developed over the past decade,most of these algorithms are either not accessible,readily available,or hard to implement for researchers who are not well versed in programming.We developed a user-friendly MATLAB-based graphical user interface(GUI;RACT2D)that facilitates back-projection and model-based image reconstructions for twodimensional RACT problems.We included numerical and experimental X-ray-induced acoustic datasets to demonstrate the capabilities of the GUI.The developed algorithms support parallel computing for evaluating reconstructions using the cores of the computer,thus further accelerating the reconstruction speed.We also share the MATLAB-based codes for evaluating RACT reconstructions,which users with MATLAB programming expertise can further modify to suit their needs.The shared GUI and codes can be of interest to researchers across the globe and assist them in e±cient evaluation of improved RACT reconstructions.展开更多
The PHYGUI for the PHYLIP package is a simple and user-friendly piece of software that acts such as a Windows based graphical-user-interface for the PHYLIP phylogenetic data analysis package. PHYLIP is a useful and po...The PHYGUI for the PHYLIP package is a simple and user-friendly piece of software that acts such as a Windows based graphical-user-interface for the PHYLIP phylogenetic data analysis package. PHYLIP is a useful and powerful tool for phylogenetic research that is regretfully operated using a character-user-interface. Therefore, PHYLIP is difficult for beginner level users. The PHYGUI for PHYLIP adds a GUI function, which makes it a more user-friendly and powerful tool. PHYGUI runs on multiple platforms such as MS-Windows and X windows on Mac OS-X and Linux systems and is mainly operated using a mouse. The input data file and the output result data files can be viewed and edited using internal or ex-ternal text editors, which can be accessed via a button on the PHYGUI for PHYLIP.展开更多
Graphical abstracts(GAs)are emerging as a pivotal tool in medical literature,enhancing the dissemination and comprehension of complex clinical data through visual summaries.This editorial highlights the significant ad...Graphical abstracts(GAs)are emerging as a pivotal tool in medical literature,enhancing the dissemination and comprehension of complex clinical data through visual summaries.This editorial highlights the significant advantages of GAs,including improved clarity,increased reader engagement,and enhanced visibility of research findings.By transforming intricate scientific data into accessible visual formats,these abstracts facilitate quick and effective knowledge transfer,crucial in clinical decision-making and patient care.However,challenges such as potential data misrepresentation due to oversimplification,the skill gap in graphic design among researchers,and the lack of standardized creation guidelines pose barriers to their widespread adoption.Additionally,while software such as Adobe Illustrator,BioRender,and Canva are commonly employed to create these visuals,not all researchers may be proficient in their use.To address these issues,we recommend that academic journals establish clear guidelines and provide necessary design training to researchers.This proactive approach will ensure the creation of high-quality GAs,promote their standardization,and expand their use in clinical reporting,ultimately benefiting the medical community and improving healthcare outcomes.展开更多
Steganography is a technology that discreetly embeds secret information into the redundant space of a carrier,enabling covert communication.As generative models continue to advance,steganography has evolved from tradi...Steganography is a technology that discreetly embeds secret information into the redundant space of a carrier,enabling covert communication.As generative models continue to advance,steganography has evolved from traditional modification-based methods to generative steganography,which includes generative linguistic and image based forms.However,while large model agents are rapidly emerging,no method has exploited the stable redundant space in their action processes.Inspired by this insightful observation,we propose a steganographic method leveraging large model agents,employing their actions to conceal secret messages.In this paper,we introduce StegoAgent,a generative steganography framework based on graphical user interface(GUI)agents,which effectively demonstrates the remarkable potential and effectiveness of large model agent-based steganographic methods.展开更多
We present CrazyBeachball,a MATLAB-based graphical user interface(GUI)software package designed for focal mechanism inversion using P-wave first-motion polarity and S/P amplitude ratio data.CrazyBeachball integrates s...We present CrazyBeachball,a MATLAB-based graphical user interface(GUI)software package designed for focal mechanism inversion using P-wave first-motion polarity and S/P amplitude ratio data.CrazyBeachball integrates seismic waveform visualization,first-motion polarity picking,and focal mechanism inversion into a single,interactive platform.Unlike conventional methods that involve separate,independent steps,CrazyBeachball streamlines the process and eliminates the need for external data conversion.Its user-friendly interface allows for efficient focal mechanism determination,while its human-machine interaction facilitates enhanced quality control.We demonstrate its effectiveness by determining focal mechanisms for 21 aftershocks from the 2021 M_(S)6.4 Yangbi earthquake sequence,with results aligning with the regional stress field and fault zone geometry.This open-source software package also allows for user customization,enabling adaptation for specific research needs.展开更多
The object of study selected for this paper is the Longevity Preface of the more controversially evaluated and less studied ancient writings of Qui Youguang.These essays are also the most included in the collection of...The object of study selected for this paper is the Longevity Preface of the more controversially evaluated and less studied ancient writings of Qui Youguang.These essays are also the most included in the collection of Qui Youguang’s writings,with differentiated content tendencies and a gradual convergence in the genre’s style.The artistic value embedded in the creation of Longevity Preface is rich in research value.The topic of this study is to analyze the innovations in the artistic characteristics of Longevity Preface by focusing on the specific breakthroughs in the image of the preface master,the expression of values,and the stylistic paradigm of Longevity Preface,so as to examine the contribution of Longevity Preface in the development of the genre.展开更多
Objective:To evaluate the efficacy of the modified Gui Fu Ling Wu Decoction in treating diabetic nephropathy(DN)of the spleen-kidney Yang deficiency type.Methods:A total of 100 DN patients admitted to Changyi Traditio...Objective:To evaluate the efficacy of the modified Gui Fu Ling Wu Decoction in treating diabetic nephropathy(DN)of the spleen-kidney Yang deficiency type.Methods:A total of 100 DN patients admitted to Changyi Traditional Chinese Medicine Hospital between August 2023 and March 2024 were included in the study.Patients were randomly divided into a control group and a study group,each comprising 50 cases,using a computerized random number generator.The control group received kallikrein treatment,while the study group received a combination of kallikrein and the modified Gui Fu Ling Wu Decoction.Blood glucose control,renal function,and inflammatory markers were assessed before and after treatment in both groups.Results:Before treatment,there were no significant differences in blood glucose and renal function indicators between the two groups(P>0.05).After treatment,postprandial blood glucose,fasting blood glucose,24-hour urinary protein,urinary microalbumin,serum creatinine,serum C-reactive protein(CRP),and interleukin-6 levels significantly decreased in both groups,with the study group showing superior results compared to the control group(P<0.05).Conclusion:The combination of Gui Fu Ling Wu Decoction and kallikrein for treating spleen-kidney Yang deficiency type DN significantly improves blood glucose control,enhances renal function,and reduces inflammatory responses.展开更多
Chronic glomerulonephritis is a renal disease characterized by multifactorial etiology,intricate pathogenesis,and persistent inflammatory response involving macrophages as the principal inflammatory cells.The polariza...Chronic glomerulonephritis is a renal disease characterized by multifactorial etiology,intricate pathogenesis,and persistent inflammatory response involving macrophages as the principal inflammatory cells.The polarization of macrophages into anti-inflammatory and pro-inflammatory phenotypes necessitates a delicate balance in chronic glomerulonephritis,mirroring the concept of yin-yang equilibrium in Chinese medicine theory pertaining to kidney function.Clinical studies have demonstrated the efficacy of Jin Gui Shen Qi Pills in the treatment of chronic glomerulonephritis,while pharmacological studies have revealed that the formula theory of Jin Gui Shen Qi Pills can modulate macrophage polarization and enhance the equilibrium between anti-inflammatory and pro-inflammatory activities.This article examines the correlation between the formula theory of Jin Gui Shen Qi Pills and the concepts of yin and yang by utilizing theoretical analysis,as well as incorporating findings from contemporary clinical and experimental studies.The study aims to elucidate the connection between the pathogenesis of chronic glomerulonephritis and the polarization of macrophages,ultimately proposing that Jin Gui Shen Qi Pills can potentially regulate macrophage polarization as a treatment for chronic glomerulonephritis.The proposition is made that Jin Gui Shen Qi Pills plays a regulatory role in macrophage polarization for the treatment of chronic glomerulonephritis,aiming to establish equilibrium between anti-inflammatory and pro-inflammatory responses,thereby offering a novel approach for integrating Chinese and Western medicine in the clinical management of chronic glomerulonephritis.展开更多
文摘移动应用是近10年来兴起的新型计算模式,深刻地影响人民的生活方式.移动应用主要以图形用户界面(graphical user interface,GUI)方式交互,而对其进行人工测试需要消耗大量人力和物力.为此,研究者提出针对移动应用GUI的测试自动生成技术以提升测试效率并检测潜在缺陷.收集了145篇相关论文,系统地梳理、分析和总结现有工作.提出了“测试生成器-测试环境”研究框架,将该领域的研究按照所属模块进行分类.特别地,依据测试生成器所基于的方法,将现有方法大致分为基于随机、基于启发式搜索、基于模型、基于机器学习和基于测试迁移这5个类别.此外,还从缺陷类别和测试动作等其他分类维度梳理现有方法.收集了该领域中较有影响力的数据集和开源工具.最后,总结当前面临的挑战并展望未来的研究方向.
基金supported by the National Institute of Health (R37CA240806)and American Cancer Society (133697-RSG-19-110-01-CCE)support from UCI Chao Family Comprehensive Cancer Center (P30CA062203).
文摘Radiation-induced acoustic computed tomography(RACT)is an evolving biomedical imaging modality that aims to reconstruct the radiation energy deposition in tissues.Traditional backprojection(BP)reconstructions carry noisy and limited-view artifacts.Model-based algorithms have been demonstrated to overcome the drawbacks of BPs.However,model-based algorithms are relatively more complex to develop and computationally demanding.Furthermore,while a plethora of novel algorithms has been developed over the past decade,most of these algorithms are either not accessible,readily available,or hard to implement for researchers who are not well versed in programming.We developed a user-friendly MATLAB-based graphical user interface(GUI;RACT2D)that facilitates back-projection and model-based image reconstructions for twodimensional RACT problems.We included numerical and experimental X-ray-induced acoustic datasets to demonstrate the capabilities of the GUI.The developed algorithms support parallel computing for evaluating reconstructions using the cores of the computer,thus further accelerating the reconstruction speed.We also share the MATLAB-based codes for evaluating RACT reconstructions,which users with MATLAB programming expertise can further modify to suit their needs.The shared GUI and codes can be of interest to researchers across the globe and assist them in e±cient evaluation of improved RACT reconstructions.
文摘The PHYGUI for the PHYLIP package is a simple and user-friendly piece of software that acts such as a Windows based graphical-user-interface for the PHYLIP phylogenetic data analysis package. PHYLIP is a useful and powerful tool for phylogenetic research that is regretfully operated using a character-user-interface. Therefore, PHYLIP is difficult for beginner level users. The PHYGUI for PHYLIP adds a GUI function, which makes it a more user-friendly and powerful tool. PHYGUI runs on multiple platforms such as MS-Windows and X windows on Mac OS-X and Linux systems and is mainly operated using a mouse. The input data file and the output result data files can be viewed and edited using internal or ex-ternal text editors, which can be accessed via a button on the PHYGUI for PHYLIP.
文摘目前,针对聚晶金刚石复合片(Polycrystalline Diamond Compact,PDC)钻头软件的开发主要集中在领眼钻头上,对领眼-扩眼钻头软件的研究还未见报道,并且PDC钻头破岩性能分析常基于有限元仿真分析方法开展,存在效率较低、时间成本大、灵活度不高的局限性,极大地限制了钻头设计研发进度。为此,设计了基于Matlab/图形用户界面(Graphical User Interface,GUI)的领眼-扩眼钻头破岩性能分析平台,旨在提供一个高效的工具,用于领眼-扩眼钻头破岩性能的评估与优化。该平台利用Matlab软件的数值计算和GUI图像处理功能,采用零点遍历法,结合切削齿的切削受力模型,能够计算切削齿的切削参数和领眼-扩眼钻头的受力情况,根据环境地层参数快速优选出最佳的钻扩组合类型,并且分析出领眼-扩眼钻头水力学特性,实现其破岩性能分析功能。结果表明,该软件适应性强、效率高,能在短时间内进行批量化的不同布齿结构领眼-扩眼钻头破岩性能分析,对提高领眼-扩眼钻头设计研发具有重要指导意义。
文摘Graphical abstracts(GAs)are emerging as a pivotal tool in medical literature,enhancing the dissemination and comprehension of complex clinical data through visual summaries.This editorial highlights the significant advantages of GAs,including improved clarity,increased reader engagement,and enhanced visibility of research findings.By transforming intricate scientific data into accessible visual formats,these abstracts facilitate quick and effective knowledge transfer,crucial in clinical decision-making and patient care.However,challenges such as potential data misrepresentation due to oversimplification,the skill gap in graphic design among researchers,and the lack of standardized creation guidelines pose barriers to their widespread adoption.Additionally,while software such as Adobe Illustrator,BioRender,and Canva are commonly employed to create these visuals,not all researchers may be proficient in their use.To address these issues,we recommend that academic journals establish clear guidelines and provide necessary design training to researchers.This proactive approach will ensure the creation of high-quality GAs,promote their standardization,and expand their use in clinical reporting,ultimately benefiting the medical community and improving healthcare outcomes.
基金supported in part by the National Natural Science Foundation of China under Grant Nos.62472398 and U2336206.
文摘Steganography is a technology that discreetly embeds secret information into the redundant space of a carrier,enabling covert communication.As generative models continue to advance,steganography has evolved from traditional modification-based methods to generative steganography,which includes generative linguistic and image based forms.However,while large model agents are rapidly emerging,no method has exploited the stable redundant space in their action processes.Inspired by this insightful observation,we propose a steganographic method leveraging large model agents,employing their actions to conceal secret messages.In this paper,we introduce StegoAgent,a generative steganography framework based on graphical user interface(GUI)agents,which effectively demonstrates the remarkable potential and effectiveness of large model agent-based steganographic methods.
基金supported by the National Key Research and Development Program of China(No.2022 YFC3003504)the National Natural Science Foundation of China(No.42174058)the Guangdong Provincial Key Laboratory of Geophysical High-resolution Imaging Technology(No.2022B1212010002).
文摘We present CrazyBeachball,a MATLAB-based graphical user interface(GUI)software package designed for focal mechanism inversion using P-wave first-motion polarity and S/P amplitude ratio data.CrazyBeachball integrates seismic waveform visualization,first-motion polarity picking,and focal mechanism inversion into a single,interactive platform.Unlike conventional methods that involve separate,independent steps,CrazyBeachball streamlines the process and eliminates the need for external data conversion.Its user-friendly interface allows for efficient focal mechanism determination,while its human-machine interaction facilitates enhanced quality control.We demonstrate its effectiveness by determining focal mechanisms for 21 aftershocks from the 2021 M_(S)6.4 Yangbi earthquake sequence,with results aligning with the regional stress field and fault zone geometry.This open-source software package also allows for user customization,enabling adaptation for specific research needs.
文摘The object of study selected for this paper is the Longevity Preface of the more controversially evaluated and less studied ancient writings of Qui Youguang.These essays are also the most included in the collection of Qui Youguang’s writings,with differentiated content tendencies and a gradual convergence in the genre’s style.The artistic value embedded in the creation of Longevity Preface is rich in research value.The topic of this study is to analyze the innovations in the artistic characteristics of Longevity Preface by focusing on the specific breakthroughs in the image of the preface master,the expression of values,and the stylistic paradigm of Longevity Preface,so as to examine the contribution of Longevity Preface in the development of the genre.
基金Shandong Province Traditional Chinese Medicine Science and Technology Project(Project No.M-2023290)。
文摘Objective:To evaluate the efficacy of the modified Gui Fu Ling Wu Decoction in treating diabetic nephropathy(DN)of the spleen-kidney Yang deficiency type.Methods:A total of 100 DN patients admitted to Changyi Traditional Chinese Medicine Hospital between August 2023 and March 2024 were included in the study.Patients were randomly divided into a control group and a study group,each comprising 50 cases,using a computerized random number generator.The control group received kallikrein treatment,while the study group received a combination of kallikrein and the modified Gui Fu Ling Wu Decoction.Blood glucose control,renal function,and inflammatory markers were assessed before and after treatment in both groups.Results:Before treatment,there were no significant differences in blood glucose and renal function indicators between the two groups(P>0.05).After treatment,postprandial blood glucose,fasting blood glucose,24-hour urinary protein,urinary microalbumin,serum creatinine,serum C-reactive protein(CRP),and interleukin-6 levels significantly decreased in both groups,with the study group showing superior results compared to the control group(P<0.05).Conclusion:The combination of Gui Fu Ling Wu Decoction and kallikrein for treating spleen-kidney Yang deficiency type DN significantly improves blood glucose control,enhances renal function,and reduces inflammatory responses.
基金This work was supported by the National Natural Science Foundation of China[81774071 to M.G.].
文摘Chronic glomerulonephritis is a renal disease characterized by multifactorial etiology,intricate pathogenesis,and persistent inflammatory response involving macrophages as the principal inflammatory cells.The polarization of macrophages into anti-inflammatory and pro-inflammatory phenotypes necessitates a delicate balance in chronic glomerulonephritis,mirroring the concept of yin-yang equilibrium in Chinese medicine theory pertaining to kidney function.Clinical studies have demonstrated the efficacy of Jin Gui Shen Qi Pills in the treatment of chronic glomerulonephritis,while pharmacological studies have revealed that the formula theory of Jin Gui Shen Qi Pills can modulate macrophage polarization and enhance the equilibrium between anti-inflammatory and pro-inflammatory activities.This article examines the correlation between the formula theory of Jin Gui Shen Qi Pills and the concepts of yin and yang by utilizing theoretical analysis,as well as incorporating findings from contemporary clinical and experimental studies.The study aims to elucidate the connection between the pathogenesis of chronic glomerulonephritis and the polarization of macrophages,ultimately proposing that Jin Gui Shen Qi Pills can potentially regulate macrophage polarization as a treatment for chronic glomerulonephritis.The proposition is made that Jin Gui Shen Qi Pills plays a regulatory role in macrophage polarization for the treatment of chronic glomerulonephritis,aiming to establish equilibrium between anti-inflammatory and pro-inflammatory responses,thereby offering a novel approach for integrating Chinese and Western medicine in the clinical management of chronic glomerulonephritis.
