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Inhibiting Effects of S.acus Linnaeus Extracts on GLT-82 Tumor Cell Lines
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作者 Li Chun-xiang Zhu Shun-ying +3 位作者 Bian Hong-rong Ju Xing-song Zhu Xiao-mei Zou Guo-lin 《Wuhan University Journal of Natural Sciences》 CAS 2002年第4期502-506,共5页
HailongS. acus Linnaeus was chosen as the experimental material in the experiments and changes of cell morphology, forming rate of clone and changes of division index were conducted to identify the inhibiting effects ... HailongS. acus Linnaeus was chosen as the experimental material in the experiments and changes of cell morphology, forming rate of clone and changes of division index were conducted to identify the inhibiting effects of Hailong extract on human tumor cell lines (GLT-82). Four days after medication, most of the cells changed their normal morphology of tumor cells and became round, broken and even broke into pieces. The inhibiting rates could reach 75.1% on the fourth day. The division index reduced strongly and the clone could not form or the forming rate was very low. With the extract concentration increasing and the time prolonging, the inhibiting effect increased. These results indicate that Hailong has striking anti-tumor effects and will have a perfect future in the fields of treatment and prevention of cancer. 展开更多
关键词 S. acus Linnaeus extract glt-82 inhibiting effects
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尖海龙提取物对癌细胞杀伤作用的研究 被引量:2
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作者 李春香 邹国林 《中医药学刊》 2001年第6期575-576,579,共3页
尖海龙为重要的海洋中药 ,提取物对Hela、SK -RB - 3细胞具有显著的抑制和杀伤作用。制备尖海龙提取物 ,再将其作用于GLT - 82细胞系 ,根据抗癌药物的筛选程序 ,从细胞形态变化、细胞计数、集落形成率、细胞分裂指数变化观察药效。结果... 尖海龙为重要的海洋中药 ,提取物对Hela、SK -RB - 3细胞具有显著的抑制和杀伤作用。制备尖海龙提取物 ,再将其作用于GLT - 82细胞系 ,根据抗癌药物的筛选程序 ,从细胞形态变化、细胞计数、集落形成率、细胞分裂指数变化观察药效。结果表明 ,尖海龙提取物可改变GLT - 82肿瘤细胞的正常生活形态 ,又可显著抑制其增殖 ,降低集落形成率 ,减少分裂指数 ,从而充分证实尖海龙提取物具有抗癌效应 ,可在显微镜下观察不同时期细胞的生长状态及细胞形态 ,其在癌症的治疗与预防方面将有广阔的前景。 展开更多
关键词 尖海龙 提取物 glt-82细胞株 抑制作用 癌细胞
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