Anemia is a common yet often overlooked complication in patients with type 2 diabetes mellitus(T2DM),particularly those with chronic kidney disease.It significantly impacts patients'quality of life,cardiovascular ...Anemia is a common yet often overlooked complication in patients with type 2 diabetes mellitus(T2DM),particularly those with chronic kidney disease.It significantly impacts patients'quality of life,cardiovascular health,and treatment outcomes.Despite its high prevalence,current clinical guidelines lack specific recommendations for anemia prevention and management in T2DM,especially in the context of newer antidiabetic therapies.This review explores the potential of emerging antidiabetic medications,such as sodium-glucose cotransporter-2 inhibitors,glucagon-like peptide-1 receptor agonists(GLP-1 RAs),and combined GLP-1-RA/GIP to mitigate anemia risk.Early detection and management of anemia in T2DM patients are crucial for improving glycemic control,reducing cardiovascular morbidity,and enhancing overall treatment outcomes.This review underscores the need for further research to better understand the mechanisms by which these novel therapies influence anemia risk and to integrate these findings into clinical practice.展开更多
创新是中国制造业转型发展的动力源泉,要依靠创新促进中国制造业从制造业集聚的世界工厂(全球制造业中心)转向全球制造业创新中心。从三个方面探讨中国由世界工厂(全球制造业中心)成为全球制造业创新中心的转变机制。首先,中国制造业已...创新是中国制造业转型发展的动力源泉,要依靠创新促进中国制造业从制造业集聚的世界工厂(全球制造业中心)转向全球制造业创新中心。从三个方面探讨中国由世界工厂(全球制造业中心)成为全球制造业创新中心的转变机制。首先,中国制造业已经成为世界工厂(全球制造业中心),这有助于相关科技活动的发展;其次,中国制造业与科技创新活动之间形成正反馈效应的创新系统;最后,由封闭走向开放式创新体系的多要素共同决定中国的创新产出,决定中国全球制造业创新中心的建立。结合2002-2017年我国29个省的面板数据,采用递归方法(recursive regression)对地理创新生产函数(Geographical Innovation Production Function,简称GIP函数)进一步扩展,结果显示:中国制造业世界工厂(全球制造业中心)积极促进了企业R&D等科技活动;科技活动与制造业之间相互影响,但正反馈效果不明显;开放条件下相关科技活动和国际技术溢出、区域技术溢出等因素与创新产出是正相关的,而R&D人员投入与创新产出之间呈负相关,其效果还有待加强。展开更多
文摘Anemia is a common yet often overlooked complication in patients with type 2 diabetes mellitus(T2DM),particularly those with chronic kidney disease.It significantly impacts patients'quality of life,cardiovascular health,and treatment outcomes.Despite its high prevalence,current clinical guidelines lack specific recommendations for anemia prevention and management in T2DM,especially in the context of newer antidiabetic therapies.This review explores the potential of emerging antidiabetic medications,such as sodium-glucose cotransporter-2 inhibitors,glucagon-like peptide-1 receptor agonists(GLP-1 RAs),and combined GLP-1-RA/GIP to mitigate anemia risk.Early detection and management of anemia in T2DM patients are crucial for improving glycemic control,reducing cardiovascular morbidity,and enhancing overall treatment outcomes.This review underscores the need for further research to better understand the mechanisms by which these novel therapies influence anemia risk and to integrate these findings into clinical practice.
文摘创新是中国制造业转型发展的动力源泉,要依靠创新促进中国制造业从制造业集聚的世界工厂(全球制造业中心)转向全球制造业创新中心。从三个方面探讨中国由世界工厂(全球制造业中心)成为全球制造业创新中心的转变机制。首先,中国制造业已经成为世界工厂(全球制造业中心),这有助于相关科技活动的发展;其次,中国制造业与科技创新活动之间形成正反馈效应的创新系统;最后,由封闭走向开放式创新体系的多要素共同决定中国的创新产出,决定中国全球制造业创新中心的建立。结合2002-2017年我国29个省的面板数据,采用递归方法(recursive regression)对地理创新生产函数(Geographical Innovation Production Function,简称GIP函数)进一步扩展,结果显示:中国制造业世界工厂(全球制造业中心)积极促进了企业R&D等科技活动;科技活动与制造业之间相互影响,但正反馈效果不明显;开放条件下相关科技活动和国际技术溢出、区域技术溢出等因素与创新产出是正相关的,而R&D人员投入与创新产出之间呈负相关,其效果还有待加强。
