Brain tumor segmentation from Magnetic Resonance Imaging(MRI)supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans,making it a crucial yet challenging task.Supervised m...Brain tumor segmentation from Magnetic Resonance Imaging(MRI)supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans,making it a crucial yet challenging task.Supervised models such as 3D U-Net perform well in this domain,but their accuracy significantly improves with appropriate preprocessing.This paper demonstrates the effectiveness of preprocessing in brain tumor segmentation by applying a pre-segmentation step based on the Generalized Gaussian Mixture Model(GGMM)to T1 contrastenhanced MRI scans from the BraTS 2020 dataset.The Expectation-Maximization(EM)algorithm is employed to estimate parameters for four tissue classes,generating a new pre-segmented channel that enhances the training and performance of the 3DU-Net model.The proposed GGMM+3D U-Net framework achieved a Dice coefficient of 0.88 for whole tumor segmentation,outperforming both the standard multiscale 3D U-Net(0.84)and MMU-Net(0.85).It also delivered higher Intersection over Union(IoU)scores compared to models trained without preprocessing or with simpler GMM-based segmentation.These results,supported by qualitative visualizations,suggest that GGMM-based preprocessing should be integrated into brain tumor segmentation pipelines to optimize performance.展开更多
基金Princess Nourah Bint Abdulrahman University Researchers Supporting Project number(PNURSP2025R826),Princess Nourah Bint Abdulrahman University,Riyadh,Saudi ArabiaNorthern Border University,Saudi Arabia,for supporting this work through project number(NBU-CRP-2025-2933).
文摘Brain tumor segmentation from Magnetic Resonance Imaging(MRI)supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans,making it a crucial yet challenging task.Supervised models such as 3D U-Net perform well in this domain,but their accuracy significantly improves with appropriate preprocessing.This paper demonstrates the effectiveness of preprocessing in brain tumor segmentation by applying a pre-segmentation step based on the Generalized Gaussian Mixture Model(GGMM)to T1 contrastenhanced MRI scans from the BraTS 2020 dataset.The Expectation-Maximization(EM)algorithm is employed to estimate parameters for four tissue classes,generating a new pre-segmented channel that enhances the training and performance of the 3DU-Net model.The proposed GGMM+3D U-Net framework achieved a Dice coefficient of 0.88 for whole tumor segmentation,outperforming both the standard multiscale 3D U-Net(0.84)and MMU-Net(0.85).It also delivered higher Intersection over Union(IoU)scores compared to models trained without preprocessing or with simpler GMM-based segmentation.These results,supported by qualitative visualizations,suggest that GGMM-based preprocessing should be integrated into brain tumor segmentation pipelines to optimize performance.
