Objective: To study the tr eatment of postope rative gast ropa resis in pa ti ents with gast ric cancer. Methods: 18 patients with gast ropa resis afte r gast ric cance r sur gery were divided into two gr oups, includ...Objective: To study the tr eatment of postope rative gast ropa resis in pa ti ents with gast ric cancer. Methods: 18 patients with gast ropa resis afte r gast ric cance r sur gery were divided into two gr oups, including 10 pa ti ents in the obse rva tion group and 8 pati ents in the cont rol group. The observation group was treated with traditional Chinese medicine combined with warm acupuncture and moxibustion, and the control group was treated with western medicine. Results: After 7 days tr eatment, the re was significant diffe rence in cure r ate and total effective rate between the two groups (P < 0.01), and the treatment group was obviously superior to the control group. Conclusion: Traditional Chinese medicine combined with warm acupuncture is effective in the treatment of postoperative gastroparesis of gastric cancer.展开更多
目的:建立一种逆转录-实时定量PCR(R T-Q PCR)检测大鼠胃组织中胃泌素(Gast)和胃动素(Mln)m R N A表达的方法。方法:提取大鼠胃组织总RNA,逆转录合成c DNA,利用SYBRGreen荧光染料法实时检测Gast和Mlnm RNA的表达水平。通过溶解曲线分析...目的:建立一种逆转录-实时定量PCR(R T-Q PCR)检测大鼠胃组织中胃泌素(Gast)和胃动素(Mln)m R N A表达的方法。方法:提取大鼠胃组织总RNA,逆转录合成c DNA,利用SYBRGreen荧光染料法实时检测Gast和Mlnm RNA的表达水平。通过溶解曲线分析检测特异性,以管家基因β-actin为内参对Gast和Mln进行定量分析。结果:建立的大鼠Gast和Mlnm RNART-QPCR检测方法具有良好的特异性和敏感性。结论:成功建立RT-QPCR检测Gast和Mlnm RNA基因表达的方法。展开更多
突发水污染事故后,高效准确模拟预测是快速采取有效防控措施和制定应急预案的基础。采用基于非均匀网格的图形处理器(graphics processing unit,GPU)加速的水动力及污染物输移数值模型(GPU accelerated surface water flow and associat...突发水污染事故后,高效准确模拟预测是快速采取有效防控措施和制定应急预案的基础。采用基于非均匀网格的图形处理器(graphics processing unit,GPU)加速的水动力及污染物输移数值模型(GPU accelerated surface water flow and associated transport,GAST)对暴雨山洪或溃坝洪水引起的突发水污染事故中污染物输移规律进行了模拟预测。模型采用Godunov格式的有限体积法求解二维浅水方程和污染物输移方程,采用一种基于HLLC(Harten-Lax-Van Leer-contact)的近似黎曼求解器计算单元网格界面通量,采用二阶高精度格式(monotonic upstream-centred scheme for conservation laws,MUSCL)限坡线性重建和龙格-库塔时间积分法实现了二阶精度,同时采用GPU加速计算技术提高模型计算效率。算例结果表明:采用非均匀网格技术局部细化地形复杂区域生成精细网格,地势平坦区域粗化网格,大幅度减少了计算域网格数量,并且在保证模拟精度的同时,提升了模型计算效率。该模型可高效准确地模拟突发水污染事件中污染物输移过程,适用于大规模水污染事故的快速预警和评估。展开更多
A 4-mo history of both epigastralgia and back pain was presented in a 39-year-old male. Computed tomography showed right lung nodule and abdominal mass attached to the gastric wall, measuring approximately 30 mm and 7...A 4-mo history of both epigastralgia and back pain was presented in a 39-year-old male. Computed tomography showed right lung nodule and abdominal mass attached to the gastric wall, measuring approximately 30 mm and 70 mm in diameter. Since biopsy samples from the lung and abdomen revealed poorly differentiated adenocarcinoma and malignant tumor, clinicians first interpreted the abdominal mass as metastatic carcinoma, and a right lower lobectomy with following resection of the mass was performed. Gross examination of both lesions displayed gray-whitish to yellow-whitish cut surfaces with hemorrhagic and necrotic foci, and the mass attached to the serosa of the lesser curvature on the gastric body. On microscopic examination, the lung tumor was composed of a proliferation of highly atypical epithelial cells having abundant eosinophilic cytoplasm, predominantly arranged in an acinar or solid growth pattern with vessel permeation, while the abdominal tumor consisted of sheets or nests with markedly atypical epithelioid cells having pleomorphic nuclei and abundant eosinophilic to clear cytoplasm focally in a radial perivascular or infiltrative growth pattern. Immunohistochemically, the latter cells were positive for HMB45 or α-smooth muscle actin, but the former ones not. Therefore, we finally made a diagnosis of malignant perivascular epithelioid cell tumor(PEComa) arising in the gastric serosa, combined with primary lung adenocarcinoma. Furthermore, small papillary car-cinoma of the thyroid gland was identified. The current case describes the coincidence of malignant PEComa with other carcinomas, posing a challenge in distinction from metastatic tumor disease.展开更多
Objective: to explore the curative effect of Mongolian medicine Siwei Guangming Salt Decoction Powder and Hadunhai Lumule Jiuwei Pills on chronic gastroenteritis. Methods: 100 college students with chronic gastroenter...Objective: to explore the curative effect of Mongolian medicine Siwei Guangming Salt Decoction Powder and Hadunhai Lumule Jiuwei Pills on chronic gastroenteritis. Methods: 100 college students with chronic gastroenteritis admitted from October 2019 to April 2021 were selected and the clinical data were analyzed retrospectively. Thirty-nine patients receiving conventional domperidone plus reductive changyanning as the control group, and 61 patients receiving Mongolian medicine Siwei Guangming Salt Decoction Powder combined with Hadunhai Lumule Jiuwei Pills as the observation group. The changes of inflammatory factors, gastrointestinal hormones and clinical symptoms of the two groups were compared before and after treatment for one month. Results: after one month of treatment, the levels of tumor necrosis factor, interleukin -6, neutrophil colony-stimulating factor, macrophage colony-stimulating factor and vasoactive peptide in serum of the two groups of patients were significantly lower than before treatment, and the degree of decrease in the observation group was better than before treatment. Compared with the control group, there was a statistically significant difference (P < 0.05). After one month of treatment, the variables and duration of diarrhea in both patient groups were significantly improved, and the improvement in the observation group was better than that in the control group. There was a statistical difference between the two groups (P < 0.05). No serious side effects occurred during the treatment of the two groups. Conclusion: In the treatment of chronic gastroenteritis patients, the combination of Mongolian medicine Siwei Guangming Salt Decoction Powder and Hadunhai Lumule Jiuwei Pills has significant curative effect. It can effectively reduce the inflammatory reaction and gastrointestinal hormone levels, improve clinical symptoms, and have high safety and high application significance.展开更多
文摘Objective: To study the tr eatment of postope rative gast ropa resis in pa ti ents with gast ric cancer. Methods: 18 patients with gast ropa resis afte r gast ric cance r sur gery were divided into two gr oups, including 10 pa ti ents in the obse rva tion group and 8 pati ents in the cont rol group. The observation group was treated with traditional Chinese medicine combined with warm acupuncture and moxibustion, and the control group was treated with western medicine. Results: After 7 days tr eatment, the re was significant diffe rence in cure r ate and total effective rate between the two groups (P < 0.01), and the treatment group was obviously superior to the control group. Conclusion: Traditional Chinese medicine combined with warm acupuncture is effective in the treatment of postoperative gastroparesis of gastric cancer.
文摘目的:建立一种逆转录-实时定量PCR(R T-Q PCR)检测大鼠胃组织中胃泌素(Gast)和胃动素(Mln)m R N A表达的方法。方法:提取大鼠胃组织总RNA,逆转录合成c DNA,利用SYBRGreen荧光染料法实时检测Gast和Mlnm RNA的表达水平。通过溶解曲线分析检测特异性,以管家基因β-actin为内参对Gast和Mln进行定量分析。结果:建立的大鼠Gast和Mlnm RNART-QPCR检测方法具有良好的特异性和敏感性。结论:成功建立RT-QPCR检测Gast和Mlnm RNA基因表达的方法。
文摘A 4-mo history of both epigastralgia and back pain was presented in a 39-year-old male. Computed tomography showed right lung nodule and abdominal mass attached to the gastric wall, measuring approximately 30 mm and 70 mm in diameter. Since biopsy samples from the lung and abdomen revealed poorly differentiated adenocarcinoma and malignant tumor, clinicians first interpreted the abdominal mass as metastatic carcinoma, and a right lower lobectomy with following resection of the mass was performed. Gross examination of both lesions displayed gray-whitish to yellow-whitish cut surfaces with hemorrhagic and necrotic foci, and the mass attached to the serosa of the lesser curvature on the gastric body. On microscopic examination, the lung tumor was composed of a proliferation of highly atypical epithelial cells having abundant eosinophilic cytoplasm, predominantly arranged in an acinar or solid growth pattern with vessel permeation, while the abdominal tumor consisted of sheets or nests with markedly atypical epithelioid cells having pleomorphic nuclei and abundant eosinophilic to clear cytoplasm focally in a radial perivascular or infiltrative growth pattern. Immunohistochemically, the latter cells were positive for HMB45 or α-smooth muscle actin, but the former ones not. Therefore, we finally made a diagnosis of malignant perivascular epithelioid cell tumor(PEComa) arising in the gastric serosa, combined with primary lung adenocarcinoma. Furthermore, small papillary car-cinoma of the thyroid gland was identified. The current case describes the coincidence of malignant PEComa with other carcinomas, posing a challenge in distinction from metastatic tumor disease.
文摘Objective: to explore the curative effect of Mongolian medicine Siwei Guangming Salt Decoction Powder and Hadunhai Lumule Jiuwei Pills on chronic gastroenteritis. Methods: 100 college students with chronic gastroenteritis admitted from October 2019 to April 2021 were selected and the clinical data were analyzed retrospectively. Thirty-nine patients receiving conventional domperidone plus reductive changyanning as the control group, and 61 patients receiving Mongolian medicine Siwei Guangming Salt Decoction Powder combined with Hadunhai Lumule Jiuwei Pills as the observation group. The changes of inflammatory factors, gastrointestinal hormones and clinical symptoms of the two groups were compared before and after treatment for one month. Results: after one month of treatment, the levels of tumor necrosis factor, interleukin -6, neutrophil colony-stimulating factor, macrophage colony-stimulating factor and vasoactive peptide in serum of the two groups of patients were significantly lower than before treatment, and the degree of decrease in the observation group was better than before treatment. Compared with the control group, there was a statistically significant difference (P < 0.05). After one month of treatment, the variables and duration of diarrhea in both patient groups were significantly improved, and the improvement in the observation group was better than that in the control group. There was a statistical difference between the two groups (P < 0.05). No serious side effects occurred during the treatment of the two groups. Conclusion: In the treatment of chronic gastroenteritis patients, the combination of Mongolian medicine Siwei Guangming Salt Decoction Powder and Hadunhai Lumule Jiuwei Pills has significant curative effect. It can effectively reduce the inflammatory reaction and gastrointestinal hormone levels, improve clinical symptoms, and have high safety and high application significance.
