期刊文献+
共找到730篇文章
< 1 2 37 >
每页显示 20 50 100
Electron G-Factor Anomaly and the Charge Thickness
1
作者 Arlen Young 《Journal of Modern Physics》 2024年第4期435-447,共13页
The electron g-factor relates the magnetic moment to the spin angular momentum. It was originally theoretically calculated to have a value of exactly 2. Experiments yielded a value of 2 plus a very small fraction, ref... The electron g-factor relates the magnetic moment to the spin angular momentum. It was originally theoretically calculated to have a value of exactly 2. Experiments yielded a value of 2 plus a very small fraction, referred to as the g-factor anomaly. This anomaly has been calculated theoretically as a power series of the fine structure constant. This document shows that the anomaly is the result of the electron charge thickness. If the thickness were to be zero, g = 2 exactly, and there would be no anomaly. As the thickness increases, the anomaly increases. An equation relating the g-factor and the surface charge thickness is presented. The thickness is calculated to be 0.23% of the electron radius. The cause of the anomaly is very clear, but why is the charge thickness greater than zero? Using the model of the interior structure of the electron previously proposed by the author, it is shown that the non-zero thickness, and thus the g-factor anomaly, are due to the proposed positive charge at the electron center and compressibility of the electron material. The author’s previous publication proposes a theory for splitting the electron into three equal charges when subjected to a strong external magnetic field. That theory is revised in this document, and the result is an error reduced to 0.4% in the polar angle where the splits occur and a reduced magnetic field required to cause the splits. 展开更多
关键词 Electron g-factor Anomaly Electron Charge Thickness Electron Positive Charge Electron Mass Thickness Electron Fractionalization Splitting the Electron Electron Compressibility Factor
在线阅读 下载PDF
Experimental Determination of the Landé g-Factors for 5s^2 ^1S and 5s5p ^3P States of the ^87Sr Atom 被引量:1
2
作者 Ben-quan Lu Yebing Wang +4 位作者 Yang Guo Qinfang Xu Mojuan Yin Jiguang LI Hong Chang 《Chinese Physics Letters》 SCIE CAS CSCD 2018年第4期30-34,共5页
We present an experimental determination on the Lande g-factors for the 5 s^2 ^1 S0 and 5 s5 p ^3P0 states in ultra-cold atomic systems, which is important for evaluating the Zeeman shift of the clock transition in th... We present an experimental determination on the Lande g-factors for the 5 s^2 ^1 S0 and 5 s5 p ^3P0 states in ultra-cold atomic systems, which is important for evaluating the Zeeman shift of the clock transition in the ^87Sr optical lattice clock. The Zeeman shift of the 5 s5 p ^3 P0-5 s^2 ^1 S0 forbidden transition is measured with the π-polarized and σ^±-polarized interrogations at different magnetic field strengths. Moreover, in the g-factor measurement with the σ^±-transition spectra, it is unnecessary to calibrate the external magnetic field. By this means, the ground state 5 s^2 ^1 S0 g-factor for the ^87Sr atom is-1.306(52) ×10^-4, which is the first experimental determination to the best of our knowledge, and the result matches very well with the theoretical estimation. The differential g-factorδg between the 5 s5 p^3 P0 state and the 5 s^2 ^1 S0 state of the ^87Sr atoms is measured in the experiment as well,which are-7.67(36) ×10^-5 with π-transition spectra and-7.72(43) X 10^-5 with σ^±-transition spectra, in good agreement with the previous report [Phys. Rev. A 76(2007) 022510]. This work can also be used for determining the differential g-factor of the clock states for the optical clocks based on other atoms. 展开更多
关键词 Sr Atom and 5s5p g-factors for 5s~2 Experimental Determination of the Land States of the
原文传递
The Real Reason Why the Electron’s Bare g-Factor Is 2 Times Classical 被引量:1
3
作者 Donald Bowen 《Journal of Modern Physics》 2016年第10期1200-1209,共10页
When analyzing an Electron’s orbit’s and movements, a “classical” bare g-factor of “1” must be used, but when analyzing just the Electron itself, a bare g-factor and gyromagnetic ratio of twice the “classical”... When analyzing an Electron’s orbit’s and movements, a “classical” bare g-factor of “1” must be used, but when analyzing just the Electron itself, a bare g-factor and gyromagnetic ratio of twice the “classical” value is needed to fit reality. Nobody has fully explained this yet. By examining the electromagnetic wave nature of the electron, it is possible to show a simple reason why its bare g-factor must be 2, without resorting to superluminal velocities or dismissing it as mystically intrinsic. A simple charged electromagnetic wave loop (CEWL) model of the electron that maintains the same electromagnetic wave nature as the high-energy photons from which electron-positron pairs form, will have exactly half of its energy in the form of magnetic energy who’s field lines are perpendicular to the direction of the charge rotation, which leads to the conclusion that only half of the electron’s electromagnetic mass is rotational mass, from which it is easy to calculate a bare g-factor of 2 using Feynman’s equation for the electron’s g-factor. 展开更多
关键词 Electron g-factor Magnetic Moment Spin Angular Momentum Magnetic Energy Charged Electromagnetic Wave Loop CEWL Pair Production General Relativity Mass de Broglie Wave
在线阅读 下载PDF
The g-factors and magnetic rotation in ^(82)Rb
4
作者 袁大庆 郑永男 +9 位作者 左翼 范平 周冬梅 吴晓光 竺礼华 李广生 许国基 樊启文 张锡珍 朱升云 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第6期207-212,共6页
The g-factors of the intra-band states 12, 13, 14, 15 in a magnetic-rotational band built on the 11 state in S2Rb are measured for the first time by using a transient magnetic field-ion implantation perturbed angular ... The g-factors of the intra-band states 12, 13, 14, 15 in a magnetic-rotational band built on the 11 state in S2Rb are measured for the first time by using a transient magnetic field-ion implantation perturbed angular distribution (TMF-IMPAD) method. The magnetic-rotational band in ^82Rb is populated by the ^60Ni(27A1,4pn)^82Rb reaction, and the time-integral Larmor precessions are measured after recoil implantation into a polarized Fe foil. The calculation of g-factors is also carried out in terms of a semi-classical model of independent particle angular momentum coupling on the basis of the four-quasiparticle configuration π(99/2)^2 Оπ(p3/2, f5/2) О v (g9/2). The measured and calculated g-factors are in good agreement with each other. The g-factors and deduced shear angles decrease with the increase of spin along the band. This clearly illustrates the shear effect of a step-by-step alignment of the valence protons and neutrons in magnetic rotation. The semi-classical calculation also shows that the alignment of the valence neutron angular momentum is faster than that of the valence protons, which results in a decrease of g-factors with increasing spin. The present results provide solid evidence of the shear mechanism of magnetic rotation. 展开更多
关键词 S2Rb magnetic rotation g-factor TMF-IMPAD
原文传递
Theoretical study of the hyperfine interaction constants, Landé g-factors, and electric quadrupole moments for the low-lying states of the 61Niq+(q=11,12,14,and 15) ions
5
作者 Ting-Xian Zhang Yong-Hui Zhang +1 位作者 Cheng-Bin Li Ting-Yun Shi 《Chinese Physics B》 SCIE EI CAS CSCD 2021年第1期65-72,共8页
Highly charged nickel ions have been suggested as candidates for the ultra-precise optical clock, meanwhile the relevant experiment has been carried out. In the framework of the multiconfiguration Dirac–Hartree–Fock... Highly charged nickel ions have been suggested as candidates for the ultra-precise optical clock, meanwhile the relevant experiment has been carried out. In the framework of the multiconfiguration Dirac–Hartree–Fock(MCDHF)method, we calculated the hyperfine interaction constants, the Landég-factors, and the electric quadrupole moments for the low-lying states in the 61Ni11+,61Ni12+,61Ni14+, and61Ni15+ ions. These states are clock states of the selected clock transitions in highly charged nickel ions(see Fig. 1). Based on discussing the effects of the electron correlations, the Breit interaction, and quantum electrodynamics(QED) effect on these physical quantities, reasonable uncertainties were obtained for our calculated results. In addition, the electric quadrupole frequency shifts and the Zeeman frequency shifts of the clock transitions concerned were analyzed. 展开更多
关键词 hyperfine interaction Landég-factors electric quadrupole moment multiconfiguration Dirac-Hartree–Fock(MCDHF)method
原文传递
Theoretical calculations on Landé g-factors and quadratic Zeeman shift coefficients of nsnp ^(3)P_(0)^(o) clock states in Mg and Cd optical lattice clocks
6
作者 卢本全 常宏 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第1期278-285,共8页
The study of magnetic field effects on the clock transition of Mg and Cd optical lattice clocks is scarce.In this work,the hyperfine-induced Landég-factors and quadratic Zeeman shift coefficients of the nsnp ^(3)... The study of magnetic field effects on the clock transition of Mg and Cd optical lattice clocks is scarce.In this work,the hyperfine-induced Landég-factors and quadratic Zeeman shift coefficients of the nsnp ^(3)P_(0)^(o) clock states for ^(111,113)Cd and ^(25)Mg were calculated by using the multi-configuration Dirac–Hartree–Fock theory.To obtain accurate values of these parameters,the impact of electron correlations and furthermore the Breit interaction and quantum electrodynamical effects on the Zeeman and hyperfine interaction matrix elements,and energy separations were investigated in detail.We also estimated the contributions from perturbing states to the Landég-factors and quadratic Zeeman shift coefficients concerned so as to truncate the summation over the perturbing states without loss of accuracy.Our calculations provide important data for estimating the first-and second-order Zeeman shifts of the clock transition for the Cd and Mg optical lattice clocks. 展开更多
关键词 optical lattice clock hyperfine-induced Landég-factor quadratic Zeeman shift coefficient Mg and Cd
原文传递
热性惊厥患儿癫痫发生情况及影响因素分析
7
作者 王冬玲 王胜男 张乐 《妇儿健康导刊》 2025年第10期41-44,共4页
目的 分析热性惊厥(FC)患儿癫痫发生情况及影响因素。方法 选取2021年5月至2023年5月滨州市中心医院收治的94例FC患儿进行回顾性分析,分析患儿癫痫发生情况,并进行单因素与多因素logistic回归分析以明确癫痫发生的危险因素。结果 纳入... 目的 分析热性惊厥(FC)患儿癫痫发生情况及影响因素。方法 选取2021年5月至2023年5月滨州市中心医院收治的94例FC患儿进行回顾性分析,分析患儿癫痫发生情况,并进行单因素与多因素logistic回归分析以明确癫痫发生的危险因素。结果 纳入的94例FC患儿中,32例发生癫痫,发生率为34.04%;发生组FC持续时间较未发生组更长,FC发作次数更多,脑电图(EEG)额颞叶区异常以及EEG非特异性异常表现占比更高(P<0.05)。多因素logistic回归分析显示,FC持续时间(OR=1.285)、FC发作次数(OR=3.718)、EEG额颞叶区异常(OR=5.875)、EEG非特异性异常表现(OR=2.312)是FC患儿发生癫痫的独立危险因素(P<0.05)。结论 FC患儿发生癫痫的风险较高,与FC持续时间、FC发作次数、EEG异常部位、EEG异常表现有关。 展开更多
关键词 脑电图 热性惊厥 癫痫 影响因素
暂未订购
Lifetime of first excited state in ^(139)La and the role of core‑excitation on L‑forbidden M1 transition
8
作者 Zhi-Xuan Wang Guang-Xin Zhang +21 位作者 Wei Jiang Meng-Lan Liu Cen-Xi Yuan Bo-Shuai Cai Chong Qi Hong-Yi Wu Zhi-Huan Li Yong-Hao Chen Rui-Rui Fan Kang Sun Wei Wang Jun Su Long Zhu Yue-Huan Wei Yu-Mei Zhang Wei Hua Bo Mei Xiao Fang Yi-Nu Zhang Chen-Chen Guo Sheng-Li Chen Xiao-Peng Zhou 《Nuclear Science and Techniques》 2025年第10期108-114,共7页
This study determined the lifetime of the first excited state(5∕2_(1)^(+))in ^(139)La via β-γ time-difference measurement using a LaBr_(3)+plastic scintillator array.This state is populated following the decay of ^... This study determined the lifetime of the first excited state(5∕2_(1)^(+))in ^(139)La via β-γ time-difference measurement using a LaBr_(3)+plastic scintillator array.This state is populated following the decay of ^(139)Ba produced in the^(138)Ba(n,γ)reaction.Compared with previous experiments using only stilbene/plastic crystals,this experiment separates the background contribution in the γ-ray spectrum owing to the high energy resolution of LaBr_(3).The L-forbidden M1 transition strength,B(M1,5∕2_(1)^(+)→7∕2_(1)^(+)),in^(139)La was measured and compared with detailed large-scale shell model calculations,with a special focus on the core-excitation effect.The results showed the importance of both proton and neutron core-excitations in explaining the M1 transition strength.Meanwhile,the effective g-factor for the tensor term of the M1 operator was smaller than the previously reported value in this region or around ^(208)Pb. 展开更多
关键词 L-forbidden M1 transition Effective g-factor LaBr_(3) Fast-timing measurement
在线阅读 下载PDF
G蛋白抑制性α亚单位1和3介导神经生长因子通路在阿尔茨海默病小鼠术后学习记忆中的作用
9
作者 拾翠翠 张玉凤 +4 位作者 张浩 崔恩惠 晏明 孙岳 孙剑 《中华老年心脑血管病杂志》 北大核心 2025年第11期1562-1566,共5页
目的探讨异氟醚麻醉对阿尔茨海默病(Alzheimer’s disease,AD)小鼠认知功能、海马神经生长因子(nerve growth factor,NGF)及其受体酪氨酸激酶A(tyrosine receptor kinase A,TrkA)信号通路的影响,并验证G蛋白抑制性α亚单位1/3(G protein... 目的探讨异氟醚麻醉对阿尔茨海默病(Alzheimer’s disease,AD)小鼠认知功能、海马神经生长因子(nerve growth factor,NGF)及其受体酪氨酸激酶A(tyrosine receptor kinase A,TrkA)信号通路的影响,并验证G蛋白抑制性α亚单位1/3(G protein inhibitoryαsubunit,Gαi1/3)在该通路中的作用。方法选择12只野生雄性小鼠为对照组,另选48只雄性APP/PSI转基因小鼠,制备AD小鼠术后认知功能障碍(post operative cognitive dysfunction,POCD)模型,将其分为AD组、AD+POCD组、腺病毒空载组、Gαi1/3过表达组,每组12只。通过Morris水迷宫和新物体识别实验评估各组学习记忆功能;采用Western blot法检测海马组织β淀粉样蛋白1-42(amyloidβ-protein 1-42,Aβ1-42)、白细胞介素6(interleukin-6,IL-6)、肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)、突触结合蛋白1(synaptotagmin-1,Syt1)、突触素1(synapsin-1,SYN1)及NGF、磷酸化TrkA(phosphorylation-TrkA,p-TrkA)、Gαi1/3、磷酸化接头蛋白Gab1(phosphorylation-Gab1,p-Gab1)表达情况。结果与对照组及AD组比较,AD+POCD组第2~4天逃避潜伏期显著延长(P<0.05),Aβ1-42、IL-6、TNF-α表达显著增加(P<0.05),Syt1、SYN1、NGF、p-TrkA、Gαi1/3、p-Gab1表达显著降低,差异有统计学意义(P<0.05);与AD+POCD组及腺病毒空载组比较,Gαi1/3过表达组第2~4天逃避潜伏期显著缩短(P<0.05),Syt1、SYN1、Gαi1/3、p-Gab1表达显著增加(P<0.05)。Gαi1/3过表达组Aβ1-42(2.00±0.39 vs 3.38±0.38)、IL-6(1.65±0.37 vs 3.36±0.39)、TNF-α(1.58±0.30 vs 2.90±0.31)表达显著低于腺病毒空载组(P<0.05)。结论异氟醚麻醉可加重AD小鼠POCD,过表达Gαi1/3可通过激活Gab1磷酸化改善认知功能。 展开更多
关键词 阿尔茨海默病 术后认知并发症 G蛋白抑制性α亚单位1/3 神经生长因子
暂未订购
The orbital g-factor and related sum rules 被引量:2
10
作者 BENTZ Wolfgang ARIMA Akito 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2011年第2期194-197,共4页
The renormalization of the orbital g-factor in nuclei is discussed on the basis of gauge invariance.The relation of the orbital g-factor to the integrated E1 photoabsorption cross section is reviewed,and its relation ... The renormalization of the orbital g-factor in nuclei is discussed on the basis of gauge invariance.The relation of the orbital g-factor to the integrated E1 photoabsorption cross section is reviewed,and its relation to the M1 sum rule for the scissors mode of deformed nuclei is examined. 展开更多
关键词 nuclear magnetic moments g-factorS giant resonances sum rules
原文传递
Anisotropies of the g-factor tensor and diamagnetic coefficient in crystal-phase quantum dots in InP nanowires 被引量:1
11
作者 Shiyao Wu Kai Peng +17 位作者 Sergio Battiato Valentina Zannier Andrea Bertoni Guido Goldoni Xin Xie Jingnan Yang Shan Xiao Chenjiang Qian Feilong Song Sibai Sun Jianchen Dang Yang Yu Fabio Beltram Lucia Sorba Ang Li Bei-bei Li Francesco Rossella Xiulai Xu 《Nano Research》 SCIE EI CAS CSCD 2019年第11期2842-2848,共7页
Crystal-phase low-dimensional structures offer great potential for the implementation of photonic devices of interest for quantum information processing.In this context,unveiling the fundamental parameters of the crys... Crystal-phase low-dimensional structures offer great potential for the implementation of photonic devices of interest for quantum information processing.In this context,unveiling the fundamental parameters of the crystal phase structure is of much relevance for several applications.Here,we report on the anisotropy of the g-factor tensor and diamagnetic coefficient in wurtzite/zincblende(WZ/ZB)crystal-phase quantum dots(QDs)realized in single InP nanowires.The WZ and ZB alternating axial sections in the NWs are identified by high-angle annular dark-field scanning transmission electron microscopy.The electron(hole)g-factor tensor and the exciton diamagnetic coefficients in WZ/ZB crystal-phase QDs are determined through micro-photoluminescence measurements at low temperature(4.2 K)with different magnetic field configurations,and rationalized by invoking the spin-correlated orbital current model.Our work provides key parameters for band gap engineering and spin states control in crystal-phase low-dimensional structures in nanowires. 展开更多
关键词 g-factor tensor diamagnetic coefficient crystal-phase quantum dot InP NWs
原文传递
影响营运客车内饰材料氧指数检测因素的研究
12
作者 任俊侠 向倩瑶 +2 位作者 陈英 方刚 陈进秋 《时代汽车》 2025年第10期128-130,共3页
通过对营运客车内饰材料中影响氧指数检测结果的各种因素进行试验分析,对试验过程中提出了建议,对试验人员在分析检测原因时提供参考方向,从而保证结果的准确性和可靠性。
关键词 氧指数 客车内饰材料 影响因素
在线阅读 下载PDF
Proton alignment in ^(82)Sr investigated by g-factor measurements
13
作者 范平 袁大庆 +9 位作者 左翼 郑永男 周冬梅 吴晓光 李广生 竺礼华 许国基 樊启文 张锡珍 朱升云 《Chinese Physics C》 SCIE CAS CSCD 2009年第S1期206-208,共3页
The proton alignment in 82Sr has been investigated by the g-factor measurements of the ground state rotational band levels up to spin I = 8+. The g-factors were measured by a transient-magnetic-field ion implantation ... The proton alignment in 82Sr has been investigated by the g-factor measurements of the ground state rotational band levels up to spin I = 8+. The g-factors were measured by a transient-magnetic-field ion implantation perturbed angular distribution method. The obtained g-factors increase with the increasing of spin along the band and clearly show the g9/2 proton alignment that starts at I =6+. 展开更多
关键词 g-factor proton alignment TMF-IMPAD 82Sr
原文传递
Study of magnetic-rotation in ^(82)Rb byg-factor measurements
14
作者 袁大庆 郑永男 +10 位作者 左翼 范平 周冬梅 刘猛 吴晓光 竺礼华 李广生 许国基 樊启文 张锡珍 朱升云 《Chinese Physics C》 SCIE CAS CSCD 2009年第S1期188-190,共3页
Magnetic rotation in 82Rb has been investigated for the first time by g-factor measurement of intra-band states of the magnetic-rotational band built on the 11- state. The g-factors were measured by a TMF-IMPAD method... Magnetic rotation in 82Rb has been investigated for the first time by g-factor measurement of intra-band states of the magnetic-rotational band built on the 11- state. The g-factors were measured by a TMF-IMPAD method and calculated by a semi-classical model of independent particle angular momentum coupling assumption. The g-factors and deduced shears angles decrease with the increasing of spin along the band, illustrating a step-by-step alignment of the valence protons and neutrons. The rapid alignment of the valence neutrons leads to a decrease of g-factors. The present results vividly reveal the shears mechanism of magnetic rotation. 展开更多
关键词 82Rb magnetic rotation shears mechanism g-factor
原文传递
G-四链体招募转录因子调控基因转录
15
作者 齐鸣 王文梦 李当当 《中国生物化学与分子生物学报》 北大核心 2025年第4期494-504,共11页
在基因转录的经典模型中,转录因子通过与含有其“共有基序”的双链DNA(double-stranded DNA,dsDNA)结合来调控靶基因转录。与dsDNA不同,G-四链体是一种非典型的核酸二级结构,由富含鸟嘌呤的序列形成,参与调节基因转录等多种生物学过程,... 在基因转录的经典模型中,转录因子通过与含有其“共有基序”的双链DNA(double-stranded DNA,dsDNA)结合来调控靶基因转录。与dsDNA不同,G-四链体是一种非典型的核酸二级结构,由富含鸟嘌呤的序列形成,参与调节基因转录等多种生物学过程,是目前分子生物学领域研究热点。近期,多个研究组发现,与dsDNA相比,G-四链体结构更高效地招募转录因子结合到启动子上,从而激活靶基因表达。然而,目前对这种非经典的基因转录调控模型缺乏全面的总结和探讨。本文介绍了G-四链体结构特点及检测该结构的技术。G-四链体包括分子内和分子间类型,其中分子内G-四链体又分为平行、反平行和杂交类型;该结构可通过圆二色谱、核磁共振光谱和凝胶迁移等技术进行鉴定。进而讨论了G-四链体在基因转录中的调节功能。G-四链体主要在基因启动子区高度富集;早期研究揭示,G-四链体可抑制基因转录,而近期的大量研究证明,该结构具备招募转录因子激活基因转录的新功能。最后,总结了具有G-四链体结合活性的转录因子的分类,包括C 2H 2锌指、叉状头/翼状螺旋、以及p53结构域的转录因子,且DNA结合结构域决定转录因子与G-四链体结合;并对该领域的后续研究方向进行了展望。总之,本文为理解“G-四链体作为转录激活的顺式作用元件”的观点提供重要指导。 展开更多
关键词 G-四链体 转录因子 启动子 基因转录
原文传递
Optical properties of excitons in strained Ga_x In_1-x As/GaAs quantum dot: effect of geometrical confinement on exciton g-factor
16
作者 N. R. Senthil Kumar A. John Peter Chang Woo Lee 《Chinese Optics Letters》 SCIE EI CAS CSCD 2013年第8期80-86,共7页
Taking into account anisotropy, nonparabolicity of the conduction band, and geometrical confinement, we discuss the heavy-hole excitonic states in a strained GaxIn1-xAs/GaAs quantum dot for various Ga alloy contents. ... Taking into account anisotropy, nonparabolicity of the conduction band, and geometrical confinement, we discuss the heavy-hole excitonic states in a strained GaxIn1-xAs/GaAs quantum dot for various Ga alloy contents. The strained quantum dot is considered as a spherical InAs dot surrounded by a GaAs barrier material. The dependence of the effective excitonic g-factor as a function of dot radius and Ga ion content is numerically measured. Interband optical energy with and without the parabolic effect is computed using structural confinement. The interband matrix element for different Ga concentrations is also calculated. The oscillator strength of interband transitions on the dot radius is studied at different Ga concentrations in the GaxIn1-xAs/GaAs quantum dot. Heavy-hole excitonic absorption spectra are recorded for various Ga alloy contents in the GaxIn1-xAs/GaAs quantum dot. Results show that oscillator strength diminishes when dot size decreases because of the dominance of the quantum size effect. Furthermore, exchange enhancement and exchange sDlitting increase as exciton confinement inereases. 展开更多
关键词 GAAS effect of geometrical confinement on exciton g-factor Optical properties of excitons in strained Gax In1-x As/GaAs quantum dot
原文传递
GPSM1在肺腺癌中的表达及其对肺腺癌细胞糖酵解的调控与潜在机制
17
作者 程金凤 江万里 《武汉大学学报(医学版)》 2025年第6期729-737,共9页
目的:探讨G蛋白信号调节受体1(GPSM1)在肺腺癌组织和细胞中的表达及其对肺腺癌细胞侵袭和迁移的影响与可能的机制。方法:通过生物信息学方法分析TCGA数据库,探索GPSM1在肺腺癌组织与正常肺组织中的表达差异,并使用Western Blot法和qPCR... 目的:探讨G蛋白信号调节受体1(GPSM1)在肺腺癌组织和细胞中的表达及其对肺腺癌细胞侵袭和迁移的影响与可能的机制。方法:通过生物信息学方法分析TCGA数据库,探索GPSM1在肺腺癌组织与正常肺组织中的表达差异,并使用Western Blot法和qPCR法检测人正常肺支气管肺泡上皮细胞BEAS-2B和人肺腺癌细胞A549、H1299、H460中GPSM1的表达水平,并选取GPSM1表达水平更低的H1299和H460细胞进行后续实验。构建GPSM1过表达质粒转染肺腺癌细胞,通过Transwell实验和细胞划痕实验分别检测过表达和敲低GPSM1对肺腺癌细胞侵袭和迁移的影响。使用LinkedOmics工具在线分析肺腺癌中GPSM1共表达基因并进行富集分析。通过检测糖酵解关键酶mRNA表达水平及细胞能量代谢分析明确GPSM1对肺腺癌细胞糖酵解的影响,并使用HIF-1α激动剂探索GPSM1/HIF-1α轴对肺腺癌细胞侵袭和迁移能力的影响。结果:GPSM1在肺腺癌组织和细胞中均呈低表达。过表达GPSM1后,肺腺癌细胞侵袭和迁移能力显著降低;肺腺癌内GPSM1表达参与多种生物学过程;过表达GPSM1后,肺腺癌细胞糖酵解能力下降,且糖酵解本身不影响GPSM1表达水平;GPSM1过表达伴随肺腺癌细胞内HIF-1α表达下调,且激活HIF-1α后肺腺癌细胞迁移和侵袭能力得到恢复。结论:GPSM1在肺腺癌组织和细胞中均呈低表达,其表达水平下调可能通过激活HIF-1α/糖酵解通路促进肺腺癌细胞侵袭和迁移。 展开更多
关键词 肺腺癌 G蛋白信号调节受体1 侵袭 迁移 糖酵解 缺氧诱导因子1Α
原文传递
血清HLA-G、PLGF、IL-35对夫精宫腔内人工授精妊娠结局的预测价值 被引量:1
18
作者 欧阳杰 凡永 刘萍 《生殖医学杂志》 2025年第2期164-170,共7页
目的分析血清人类白细胞抗原-G(HLA-G)、胎盘生长因子(PLGF)、白介素-35(IL-35)水平对夫精宫腔内人工授精(IUI)患者妊娠结局的预测价值。方法回顾性分析2021年3月至2023年10月在海南西部中心医院行IUI患者的临床资料,共358个周期。根据... 目的分析血清人类白细胞抗原-G(HLA-G)、胎盘生长因子(PLGF)、白介素-35(IL-35)水平对夫精宫腔内人工授精(IUI)患者妊娠结局的预测价值。方法回顾性分析2021年3月至2023年10月在海南西部中心医院行IUI患者的临床资料,共358个周期。根据妊娠结局分为妊娠组(n=62)和未妊娠组(n=296)。采用ELISA法检测患者血清HLA-G、PLGF、IL-35水平,比较各组间的一般资料、各血清因子水平;采用多因素Logistic回归分析IUI患者妊娠结局的影响因素,绘制受试者工作特征(ROC)曲线分析HLA-G、PLGF、IL-35水平对IUI患者妊娠结局的预测价值,采用Spearman及Pearson法分析HLA-G、PLGF、IL-35水平与年龄、卵巢功能指标的相关性。结果与妊娠组相比,未妊娠组的年龄、不孕年限显著升高(P<0.05),HCG日优势卵泡数>1的比例、抗苗勒管激素(AMH)水平显著降低(P<0.05),血清HLA-G、PLGF、IL-35水平显著降低(P<0.05)。Logistic回归分析显示,年龄[OR=1.405,95%CI(1.031,1.915),P=0.031]是患者妊娠结局的危险因素,血清HLA-G[OR=0.785,95%CI(0.618,0.997),P=0.047]、PLGF[OR=0.733,95%CI(0.559,0.961),P=0.024]、IL-35[OR=0.786,95%CI(0.624,0.991),P=0.041]均为妊娠结局的保护因素。ROC曲线分析表明,HLA-G、PLGF、IL-35水平、年龄以及联合预测患者妊娠结局的曲线下面积(AUC)分别为0.819、0.819、0.773、0.645、0.938,联合预测的灵敏度为83.11%,特异度为96.77%,联合预测显著优于HLA-G(Z=3.912,P=0.001)、PLGF(Z=4.111,P<0.001)、IL-35(Z=4.831,P<0.001)水平及年龄(Z=7.116,P<0.001)单独预测。相关性分析结果显示,HLA-G、IL-35水平与AMH水平呈正相关(P<0.05),PLGF水平与年龄呈负相关(P<0.05)、与AMH水平呈正相关(P<0.05)。结论经夫精IUI后未妊娠患者血清HLA-G、PLGF、IL-35水平降低,三者与年龄联合分析对妊娠结局具有一定辅助预测价值。 展开更多
关键词 夫精宫腔内人工授精 人类白细胞抗原-G 胎盘生长因子 白介素-35 妊娠结局 预测价值
暂未订购
Magnetic moments and g-factors in odd-A Ho isotopes
19
作者 E.Tabar H.Yakut +2 位作者 A.A.Kuliev H.Quliyev G.Hosgor 《Chinese Physics C》 SCIE CAS CSCD 2017年第7期52-60,共9页
The ground-state magnetic moment, g K factor and quenching spin gyromagnetic ratio have been calculated using the microscopic method based on the Quasiparticle Phonon Nuclear Model(QPNM) for ^155-169 Ho nuclei for t... The ground-state magnetic moment, g K factor and quenching spin gyromagnetic ratio have been calculated using the microscopic method based on the Quasiparticle Phonon Nuclear Model(QPNM) for ^155-169 Ho nuclei for the first time. It is shown that the residual spin-spin interactions are responsible for the core polarization,and because of the core polarization the spin gyromagnetic factors are quenched. By considering the core polarization effects, a satisfactory agreement is obtained for the computed ground state g K factor, which gives an intrinsic contribution to the magnetic moments. In order to assess the collective contribution to the magnetic moments, the rotational gyromagnetic factors g R have been also calculated within the cranking approximation using the single particle wave function of the axially symmetric Woods-Saxon potential. For the ground-state magnetic moments of odd-proton ^155-165 Ho nuclei, a good description of the experimental data is obtained with an accuracy of 0.01–0.1μN. From systematic trends, the quenching spin gyromagnetic factor, g K factor and magnetic moment have also been theoretically predicted for167,169 Ho where there is no existing experimental data. 展开更多
关键词 deformed odd-A Ho isotopes magnetic moment magnetic g-factors core-polarization QRPA
原文传递
定位格架G因子光学测量方法及可靠性评定
20
作者 郑家国 《机电产品开发与创新》 2025年第6期133-135,共3页
定位格架G因子与核电站燃料棒破损直接相关。建立可靠的G因子的测量方法,是核燃料元件制造厂必备的测量技术。本方法在国内首次利用光学方法实现了G因子的测量。通过可靠性评定试验,验证了该测量方法的测量准确度为0.0131 mm,重复性为0.... 定位格架G因子与核电站燃料棒破损直接相关。建立可靠的G因子的测量方法,是核燃料元件制造厂必备的测量技术。本方法在国内首次利用光学方法实现了G因子的测量。通过可靠性评定试验,验证了该测量方法的测量准确度为0.0131 mm,重复性为0.000063mm、复现性为0.000136mm,测量不确定度(扩展不确定度)为0.032 mm,满足G因子测量不确定度U≤0.05 mm的技术指标。本光学测量方法已完成16.9万余件定位格架G因子检测。该方法运行稳定可靠,0故障,0漏检率,0误检率,确保G因子工艺能力指数Cpk持续保持>1.9的优秀质量控制水平。 展开更多
关键词 核燃料组件 定位格架G因子 光学测量方法 可靠性评定
在线阅读 下载PDF
上一页 1 2 37 下一页 到第
使用帮助 返回顶部