Poly(3-hexylthiophene)(P3HT)is one of the most promising hole-transporting materials in the pursuit of efficient and stable perovskite solar cells due to its outstanding stability and low cost.However,the intrinsic lo...Poly(3-hexylthiophene)(P3HT)is one of the most promising hole-transporting materials in the pursuit of efficient and stable perovskite solar cells due to its outstanding stability and low cost.However,the intrinsic low carrier density of P3 HT and poor contact between the P3HT/perovskite interface always lead to a low performance of the solar cell,while conventional chemical doping always makes the films unstable and limits the scalability.In this work,for the first time,we simultaneously enhanced the hole transporting properties of P3HT film and the interface of perovskite by doping it with a judiciously designed oxidized small molecule organic semiconductor.The organic salt not only can promote the lamellar crystallinity of P3HT to obtain better charge transport properties,but also reduce the defects of perovskite.As a result,we achieved champion efficiencies of 23.0%for small-area solar cells and 18.8%for larger-area modules(48.0 cm^(2)).This efficiency is the highest value for P3HT-based perovskite modules.Moreover,the solar cells show excellent operational stability,retaining over 95%of their initial efficiencies after1200 h of continuous operation.展开更多
Photocatalytic H_(2)production from water splitting is a promising candidate for solving the increasing energy crisis and environmental issues.Herein we report a novel g-C_(3)N_(4)/Ag In_(x)S_(y)S-scheme heterojunctio...Photocatalytic H_(2)production from water splitting is a promising candidate for solving the increasing energy crisis and environmental issues.Herein we report a novel g-C_(3)N_(4)/Ag In_(x)S_(y)S-scheme heterojunction photocatalyst for water splitting into stoichiometric H_(2)and H_(2)O_(2)under visible light.The catalyst was prepared by depositing 3D bimetallic sulfide(Ag In_(x)S_(y))nanotubes onto 2D g-C_(3)N_(4)nanosheets.Owing to the special 3D-on-2D configuration,the photogenerated carriers could be rapidly transferred and effectively separated through the abundant interfacial heterostructures to avoid recombination,and therefore excellent performance for visible light-driven water splitting could be obtained,with a 24-h H_(2)evolution rate up to 237μmol g^(-1)h^(-1).Furthermore,suitable band alignment enables simultaneous H_(2)and H_(2)O_(2)production in a 1:1 stoichiometric ratio.H_(2)and H_(2)O_(2)were evolved on the conduction band of g-C_(3)N_(4)and on the valance band of Ag In_(x)S_(y),respectively.The novel 3D-on-2D configuration for heterojunction construction proposed in this work provided alternative research ideas toward photocatalytic reaction.展开更多
Electronic-state modulation strategy offers great potential in designing RuO_(2)-based bifunctionalelectrocatalysts for rechargeable Zn-air batteries(ZABs).Various three-dimensional(3D)transition metal oxides are atte...Electronic-state modulation strategy offers great potential in designing RuO_(2)-based bifunctionalelectrocatalysts for rechargeable Zn-air batteries(ZABs).Various three-dimensional(3D)transition metal oxides are attempted to couple with RuO_(2)for constructing an appropriate Ru—O—M interface.This work aims to construct Co_(3)O_(4)-RuO_(2)heterostructures on carbon sheets(Co_(3)O_(4)/RuO_(2)/NCNS)for boosting electronic transfer and regulation.Experiments and theoretical calculations identify the electronic transfer from Co_(3)O_(4)to RuO_(2)that modulates the electronic structure of metal surfaces/interfaces.Specifically,it leads to the increase in Co3+content,electron-rich state at RuO_(2)surface and electronic accumulation at interfaces.Moreover,this electronic-state modulation optimizes the d-band center in Co_(3)O_(4)/RuO_(2)that lowers the reaction barriers and endows interfaces as the biggest contributor to oxygen reduction reaction(ORR)and oxygen evolution reaction(OER)performance,The Co_(3)O_(4)/RuO_(2)/NCNS shows a quite low potential difference of 0.62 V and remarkable durability for ORR/OER.Co_(3)O_(4)/RuO_(2)/NCNS-assembled ZABs exhibit an excellent specific capacity of 818.3 mA h g^(-1)and a superior lifespan over 750 h.展开更多
The influences of two kinds of casting modules of metal casting （MC） and expandable pattern casting （EPC） on the corrosion behavior of Mg-11Gd-3Y alloy were studied by electrochemical measurements, scanning electr...The influences of two kinds of casting modules of metal casting （MC） and expandable pattern casting （EPC） on the corrosion behavior of Mg-11Gd-3Y alloy were studied by electrochemical measurements, scanning electron microscopy （SEM） observation, X-ray diffractometry （XRD） and X-ray photoelectron spectroscopy （XPS） analysis. It is found that the quantity of the Mg 24 （Gd, Y） 5 phase in MC is more than that in EPC due to the cooling rate. There is more alloying element dissolved in the matrix compared with MC. For EPC, the galvanic corrosion effect between the matrix and the Mg 24 （Gd, Y） 5 phase decreases and the corrosion resistance increases compared with the MC. The chief corrosion mode for Mg-11Gd-3Y alloy is pitting corrosion because most of the alloying elements are transformed into intermetallic phases. The average corrosion rate of the MC alloy in the immersion test is five times higher than that of EPC alloy and yttrium is present in the product film, which will provide increased protection for Mg-11Gd-3Y alloy. The electrochemical measurements and immersion test show that the EPC process increases the corrosion resistance compared with the MC Mg-11Gd-3Y alloy.展开更多
In this work,a hybrid integrated optical transmitter module was designed and fabricated.A proton-exchanged Mach–Zehnder lithium niobate(LiNbO_(3))modulator chip was chosen to enhance the output extinction ratio.A fib...In this work,a hybrid integrated optical transmitter module was designed and fabricated.A proton-exchanged Mach–Zehnder lithium niobate(LiNbO_(3))modulator chip was chosen to enhance the output extinction ratio.A fiber was used to adjust the rotation of the polarization direction caused by the optical isolator.The whole optical path structure,including the laser chip,lens,fiber,and modulator chip,was simulated to achieve high optical output efficiency.After a series of process improvements,a module with an output extinction ratio of 34 dB and a bandwidth of 20.5 GHz(from 2 GHz)was obtained.The optical output efficiency of the whole module reached approximately 21%.The link performance of the module was also measured.展开更多
MEMS swallowable capsule is a novel technology in the non-invasive surgery. This technology provides a way to diagnose directly into the deep intestinal where the traditional invasive technology implemented, such as X...MEMS swallowable capsule is a novel technology in the non-invasive surgery. This technology provides a way to diagnose directly into the deep intestinal where the traditional invasive technology implemented, such as X-Ray, endoscopy. It is a key for us to locate and track the position of a MEMS capsule in clinical applications. To solve this problem, we implemented a magnetic sensor module based on the scalar form of the magnetic dipole model,which was designed with very small size （5.2 ＊ 2. 1 ＊ 1.2 em） and easy to assemble to satisfy the system requirement. Here we discuss in detail the principle of magnetic dipole model, rules of selecting sensor and functions of the module. Some trials are established to test the characteristic of the module. The results of the Cm experiment demonstrates that the module follows the rules of the new magnetic dipole model form.展开更多
BACKGROUND Colorectal cancer(CRC)is a leading cause of cancer-related morbidity and mor-tality globally.Exosomal microRNAs(miRNAs)are known to modulate tumor progression by influencing immune responses and vascular dy...BACKGROUND Colorectal cancer(CRC)is a leading cause of cancer-related morbidity and mor-tality globally.Exosomal microRNAs(miRNAs)are known to modulate tumor progression by influencing immune responses and vascular dynamics.However,the roles of specific exosomal miRNAs,such as miR-425-5p and miR-135b-3p,in CRC remain unclear.AIM To explore the specific roles and underlying mechanisms of exosomal miR-425-5p and miR-135b-3p in CRC progression.METHODS Differentially expressed miRNAs were identified through microarray analysis of exosomes isolated from CRC tissues and adjacent normal mucosa.Functional roles of miR-425-5p and miR-135b-3p were evaluated in vitro using macrophage polarization,T cell differentiation,and vascular permeability assays,as well as in vivo tumor formation and metastasis experiments in nude mice.Validation expe-riments were performed using CRC cell lines(HCT116 and SW620).RESULTS Exosomal miR-425-5p and miR-135b-3p were significantly upregulated in CRC compared to normal tissues.Functional studies revealed that miR-425-5p promo-tes macrophage M2-like polarization and suppresses T cell proinflammatory responses,while miR-135b-3p enhances vascular permeability and angiogenesis.Inhibition of these miRNAs in CRC cell-derived exosomes significantly supp-ressed tumor growth and metastasis in nude mice,reprogramming the tumor microenvironment toward reduced angiogenesis and enhanced immune acti-vation.Combined inhibition of both miRNAs resulted in the most pronounced effects.CONCLUSION Exosomal miR-425-5p and miR-135b-3p drive CRC progression by promoting immune suppression and vascular permeability.Their inhibition offers a promising strategy for modulating the tumor microenvironment and limiting CRC metastasis.展开更多
基金financially supported by the National Natural Science Foundation of China(52472248 and 22075221)the Key Research and Development Project of Shanxi Province(202202060301003 and 202202060301015)the Innovation Program of Wuhan-Shuguang Project(2023010201020367)。
文摘Poly(3-hexylthiophene)(P3HT)is one of the most promising hole-transporting materials in the pursuit of efficient and stable perovskite solar cells due to its outstanding stability and low cost.However,the intrinsic low carrier density of P3 HT and poor contact between the P3HT/perovskite interface always lead to a low performance of the solar cell,while conventional chemical doping always makes the films unstable and limits the scalability.In this work,for the first time,we simultaneously enhanced the hole transporting properties of P3HT film and the interface of perovskite by doping it with a judiciously designed oxidized small molecule organic semiconductor.The organic salt not only can promote the lamellar crystallinity of P3HT to obtain better charge transport properties,but also reduce the defects of perovskite.As a result,we achieved champion efficiencies of 23.0%for small-area solar cells and 18.8%for larger-area modules(48.0 cm^(2)).This efficiency is the highest value for P3HT-based perovskite modules.Moreover,the solar cells show excellent operational stability,retaining over 95%of their initial efficiencies after1200 h of continuous operation.
基金financially supported by the National Natural Science Foundation of China(Nos.52362012,42077162,51978323)Natural Science Foundation of Jiangxi Province(No.2022ACB203014)+4 种基金Major Discipline Academic and Technical Leaders Training Program of Jiangxi Province(Nos.20213BCJ22018,20232BCJ22048)Natural Science Project of the Educational Department in Jiangxi Province(No.GJJ2201121)Natural Science Foundation of Nanchang Hangkong University(No.EA202202256)Educational Reform Project of Jiangxi Province(No.JXYJG-2022-135)Nanchang Hangkong University Educational Reform Project(Nos.sz2214,sz2213,JY22017,KCPY1806)。
文摘Photocatalytic H_(2)production from water splitting is a promising candidate for solving the increasing energy crisis and environmental issues.Herein we report a novel g-C_(3)N_(4)/Ag In_(x)S_(y)S-scheme heterojunction photocatalyst for water splitting into stoichiometric H_(2)and H_(2)O_(2)under visible light.The catalyst was prepared by depositing 3D bimetallic sulfide(Ag In_(x)S_(y))nanotubes onto 2D g-C_(3)N_(4)nanosheets.Owing to the special 3D-on-2D configuration,the photogenerated carriers could be rapidly transferred and effectively separated through the abundant interfacial heterostructures to avoid recombination,and therefore excellent performance for visible light-driven water splitting could be obtained,with a 24-h H_(2)evolution rate up to 237μmol g^(-1)h^(-1).Furthermore,suitable band alignment enables simultaneous H_(2)and H_(2)O_(2)production in a 1:1 stoichiometric ratio.H_(2)and H_(2)O_(2)were evolved on the conduction band of g-C_(3)N_(4)and on the valance band of Ag In_(x)S_(y),respectively.The novel 3D-on-2D configuration for heterojunction construction proposed in this work provided alternative research ideas toward photocatalytic reaction.
基金supported by the National Natural Science Foundation of China(52273264)the Outstanding Youth Fund of Heilongjiang Province(JQ 2020B002).
文摘Electronic-state modulation strategy offers great potential in designing RuO_(2)-based bifunctionalelectrocatalysts for rechargeable Zn-air batteries(ZABs).Various three-dimensional(3D)transition metal oxides are attempted to couple with RuO_(2)for constructing an appropriate Ru—O—M interface.This work aims to construct Co_(3)O_(4)-RuO_(2)heterostructures on carbon sheets(Co_(3)O_(4)/RuO_(2)/NCNS)for boosting electronic transfer and regulation.Experiments and theoretical calculations identify the electronic transfer from Co_(3)O_(4)to RuO_(2)that modulates the electronic structure of metal surfaces/interfaces.Specifically,it leads to the increase in Co3+content,electron-rich state at RuO_(2)surface and electronic accumulation at interfaces.Moreover,this electronic-state modulation optimizes the d-band center in Co_(3)O_(4)/RuO_(2)that lowers the reaction barriers and endows interfaces as the biggest contributor to oxygen reduction reaction(ORR)and oxygen evolution reaction(OER)performance,The Co_(3)O_(4)/RuO_(2)/NCNS shows a quite low potential difference of 0.62 V and remarkable durability for ORR/OER.Co_(3)O_(4)/RuO_(2)/NCNS-assembled ZABs exhibit an excellent specific capacity of 818.3 mA h g^(-1)and a superior lifespan over 750 h.
基金Project(2007CB613705)supported by the National Basic Research Program of China
文摘The influences of two kinds of casting modules of metal casting （MC） and expandable pattern casting （EPC） on the corrosion behavior of Mg-11Gd-3Y alloy were studied by electrochemical measurements, scanning electron microscopy （SEM） observation, X-ray diffractometry （XRD） and X-ray photoelectron spectroscopy （XPS） analysis. It is found that the quantity of the Mg 24 （Gd, Y） 5 phase in MC is more than that in EPC due to the cooling rate. There is more alloying element dissolved in the matrix compared with MC. For EPC, the galvanic corrosion effect between the matrix and the Mg 24 （Gd, Y） 5 phase decreases and the corrosion resistance increases compared with the MC. The chief corrosion mode for Mg-11Gd-3Y alloy is pitting corrosion because most of the alloying elements are transformed into intermetallic phases. The average corrosion rate of the MC alloy in the immersion test is five times higher than that of EPC alloy and yttrium is present in the product film, which will provide increased protection for Mg-11Gd-3Y alloy. The electrochemical measurements and immersion test show that the EPC process increases the corrosion resistance compared with the MC Mg-11Gd-3Y alloy.
基金This work was supported by National Key Research and Development Program of China(2018YFB2201101)the Strategic Priority Research Program of Chinese Academy of Sciences,Grant No.XDB43000000Beijing Municipal Science&Technology Commission,Administrative Commission of Zhongguancun Science Park No.Z201100004020004。
文摘In this work,a hybrid integrated optical transmitter module was designed and fabricated.A proton-exchanged Mach–Zehnder lithium niobate(LiNbO_(3))modulator chip was chosen to enhance the output extinction ratio.A fiber was used to adjust the rotation of the polarization direction caused by the optical isolator.The whole optical path structure,including the laser chip,lens,fiber,and modulator chip,was simulated to achieve high optical output efficiency.After a series of process improvements,a module with an output extinction ratio of 34 dB and a bandwidth of 20.5 GHz(from 2 GHz)was obtained.The optical output efficiency of the whole module reached approximately 21%.The link performance of the module was also measured.
文摘MEMS swallowable capsule is a novel technology in the non-invasive surgery. This technology provides a way to diagnose directly into the deep intestinal where the traditional invasive technology implemented, such as X-Ray, endoscopy. It is a key for us to locate and track the position of a MEMS capsule in clinical applications. To solve this problem, we implemented a magnetic sensor module based on the scalar form of the magnetic dipole model,which was designed with very small size （5.2 ＊ 2. 1 ＊ 1.2 em） and easy to assemble to satisfy the system requirement. Here we discuss in detail the principle of magnetic dipole model, rules of selecting sensor and functions of the module. Some trials are established to test the characteristic of the module. The results of the Cm experiment demonstrates that the module follows the rules of the new magnetic dipole model form.
文摘BACKGROUND Colorectal cancer(CRC)is a leading cause of cancer-related morbidity and mor-tality globally.Exosomal microRNAs(miRNAs)are known to modulate tumor progression by influencing immune responses and vascular dynamics.However,the roles of specific exosomal miRNAs,such as miR-425-5p and miR-135b-3p,in CRC remain unclear.AIM To explore the specific roles and underlying mechanisms of exosomal miR-425-5p and miR-135b-3p in CRC progression.METHODS Differentially expressed miRNAs were identified through microarray analysis of exosomes isolated from CRC tissues and adjacent normal mucosa.Functional roles of miR-425-5p and miR-135b-3p were evaluated in vitro using macrophage polarization,T cell differentiation,and vascular permeability assays,as well as in vivo tumor formation and metastasis experiments in nude mice.Validation expe-riments were performed using CRC cell lines(HCT116 and SW620).RESULTS Exosomal miR-425-5p and miR-135b-3p were significantly upregulated in CRC compared to normal tissues.Functional studies revealed that miR-425-5p promo-tes macrophage M2-like polarization and suppresses T cell proinflammatory responses,while miR-135b-3p enhances vascular permeability and angiogenesis.Inhibition of these miRNAs in CRC cell-derived exosomes significantly supp-ressed tumor growth and metastasis in nude mice,reprogramming the tumor microenvironment toward reduced angiogenesis and enhanced immune acti-vation.Combined inhibition of both miRNAs resulted in the most pronounced effects.CONCLUSION Exosomal miR-425-5p and miR-135b-3p drive CRC progression by promoting immune suppression and vascular permeability.Their inhibition offers a promising strategy for modulating the tumor microenvironment and limiting CRC metastasis.
