为研究科学有效的锂电池储能电站风险评估方法,从法律、法规、规程、标准和文献中提取并确定锂电池储能电站风险评价指标集,包括电池组、外部刺激、保护系统、运行环境、人为因素和安全管理等6个一级指标,以及电池基本情况、电池使用工...为研究科学有效的锂电池储能电站风险评估方法,从法律、法规、规程、标准和文献中提取并确定锂电池储能电站风险评价指标集,包括电池组、外部刺激、保护系统、运行环境、人为因素和安全管理等6个一级指标,以及电池基本情况、电池使用工况、电池模组状态等27个二级指标。采用序关系分析(G1)法确定指标主观权重,采用人工鱼群算法(artificial fish swarm algorithm,AFSA)确定各评价指标客观权重,采用乘积法确定最终的组合权重,结合云模型理论建立锂电池储能电站安全风险评价模型。以某电站为例开展研究,研究结果表明:储能电站风险综合期望值为61.382,风险处于较高水平,需采取适当措施进行风险防控。模型能够有效识别关键风险路径,评价结论与现场风险表现具有较高一致性。研究结果可为锂电池储能电站风险预防和管控提供参考。展开更多
目的 探究血清多聚嘧啶区结合蛋白1(polypyrimidine tract binding protein 1,PTBP1)、G蛋白信号调节因子2(regulator of G protein signaling 2,RGS2)、5-羟色胺(5-hydroxytryptamine, 5-HT)水平在慢性萎缩性胃炎(chronic atrophic gas...目的 探究血清多聚嘧啶区结合蛋白1(polypyrimidine tract binding protein 1,PTBP1)、G蛋白信号调节因子2(regulator of G protein signaling 2,RGS2)、5-羟色胺(5-hydroxytryptamine, 5-HT)水平在慢性萎缩性胃炎(chronic atrophic gastritis, CAG)诊断及病情严重程度评估中的价值。方法 选取2022年1月至2024年10月我院收治的143例CAG患者为研究组,根据胃固有腺体减少程度分为轻度组(n=26)、中度组(n=75)、重度组(n=42)。另纳入152名体检健康人群为对照组。采用酶联免疫吸附法(enzyme linked immunosorbent assay, ELISA)测定各组血清PTBP1、RGS2、5-HT的表达。Logistic回归分析CAG影响因素。ROC曲线分析血清PTBP1、RGS2、5-HT对CAG的诊断及病情严重程度评估价值。结果 与对照组相比,研究组血清PTBP1、RGS2、5-HT表达均升高(P<0.05)。重度组血清PTBP1、RGS2、5-HT高于轻度组、中度组(P<0.05),中度组血清PTBP1、5-HT高于轻度组(P<0.05)。PTBP1、RGS2、5-HT均为CAG发生的危险因素(P<0.05)。血清PTBP1、RGS2、5-HT联合诊断CAG的AUC为0.957,显著大于PTBP1(Z=6.160,P<0.001)、RGS2(Z=4.240,P<0.001)、5-HT(Z=3.248,P=0.001)单独诊断的AUC。PTBP1、RGS2、5-HT联合诊断重度CAG的AUC为0.973,显著大于PTBP1(Z=3.799,P<0.001)、RGS2(Z=5.018,P<0.001)单独诊断的AUC,与5-HT(Z=1.760,P=0.078)单独诊断的AUC,差异无统计学意义。结论 CAG患者血清PTBP1、RGS2、5-HT水平均升高,三者联合具有一定的CAG诊断及病情严重程度评估价值。展开更多
随着5G技术的广泛应用,用户通信需求和应用场景的日益复杂,对差异化的服务质量(QoS,Quality of Service)有了愈发严苛的要求。本研究提出了一种基于5G QoS标识(5G QoS Identifier,5QI)与无线频率选择优先级(RAT Frequency Selection Pri...随着5G技术的广泛应用,用户通信需求和应用场景的日益复杂,对差异化的服务质量(QoS,Quality of Service)有了愈发严苛的要求。本研究提出了一种基于5G QoS标识(5G QoS Identifier,5QI)与无线频率选择优先级(RAT Frequency Selection Priority,RFSP)联合的动态调度策略,通过改进的加权比例公平(Weighted Proportional Fair,WPF)调度算法融合接入管理-策略控制功能(Access Management-Policy Control Function,AM-PCF)动态策略机制,实现用户级与业务级的资源灵活分配。设计分层分级网络保障模型,为不同用户分配差异化的5QI和RFSP调度权重。测试结果表明,保障用户平均速率、视频播放质量等关键性能均优于普通用户,验证了差异化调度策略在复杂场景下的有效性。展开更多
As the aging population continues to grow,age-related health issues are becoming increasingly prominent,attracting widespread attention and concern from society.While research on the mechanisms of aging is relatively ...As the aging population continues to grow,age-related health issues are becoming increasingly prominent,attracting widespread attention and concern from society.While research on the mechanisms of aging is relatively extensive,studies on the association between aging and related diseases remain limited.G.lucidum,a traditional medicinal fungus,has garnered significant attention due to its diverse bioactive properties.Recent studies have revealed that G.lucidum and its active components exhibit significant potential in anti-aging and regulating dysregulation of glucose and lipid metabolism.However,a comprehensive and detailed review of recent research findings has yet to be thoroughly explored.This paper summarizes and elucidates the latest advances in the pathological mechanisms of aging-related glucose and lipid metabolism disorders by retrieving data from databases such as X-mol and PubMed,provides a detailed account of the regulatory effects of G.lucidum’s primary active components on aging and lipid metabolism,and explores their potential mechanisms.Additionally,it discusses the application prospects of G.lucidum in the fields of anti-aging and metabolic regulation,aiming to provide a reference for research on aging-mediated lipid metabolism disorders and to lay a theoretical foundation for the further development and application of G.lucidum.展开更多
Objective:To investigate the correlation between the expression of glucose-6-phosphate dehydrogenase(G6PD)and the clinicopathological characteristics,prognosis and immune cell infiltration of hepatocellular carcinoma(...Objective:To investigate the correlation between the expression of glucose-6-phosphate dehydrogenase(G6PD)and the clinicopathological characteristics,prognosis and immune cell infiltration of hepatocellular carcinoma(HCC).Methods:The expression of G6PD in liver cancer tissues and normal tissues is extracted from TCGA and GEO databases,validated by immunohistochemistry,and the correlation between G6PD expression and clinical features is analyzed.The clinical significance of G6PD in liver cancer is assessed by Kaplan-Meier,Cox regression,and prognostic line graph models.Functional enrichment analysis is performed by protein-protein interaction(PPI)network,GO/KEGG,GSEA and for G6PD-associated differentially expressed genes(DEGs).TIMER and ssGSEA packages are used to assess the correlation between expression and the level of immune cell infiltration.Results:Analysis of TCGA and GEO datasets revealed that G6PD expression is significantly upregulated in hepatocellular carcinoma tissues(P<0.001).G6PD expression is associated with histological grade,pathological stage,T-stage,vascular infiltration,and AFP level(P<0.05);HCC patients in the low G6PD expression group had longer overall survival and better prognosis compared with the high G6PD expression group(P<0.05).The level of G6PD expression affects the levels of macrophages,dendritic cells,B cells,and follicular helper T cells in the tumor microenvironment.Conclusion:High expression of G6PD is a potential biomarker for poor prognosis of hepatocellular carcinoma,and G6PD may be a target for immunotherapy of HCC.展开更多
China launched its first spaceborne Precipitation Measurement Radar(PMR)on the FY-3G satellite in April 2023.To achieve the scientific goal of measuring the three-dimensional precipitation structure,evaluating the qua...China launched its first spaceborne Precipitation Measurement Radar(PMR)on the FY-3G satellite in April 2023.To achieve the scientific goal of measuring the three-dimensional precipitation structure,evaluating the quantitative measurement ability of the PMR is critical.China operates more than 250 weather radars over the mainland.Consistency of the spaceborne radar with ground-based radars will enhance precipitation measurement ability,especially over oceans and mountains where observations are sparse.Additionally,the spaceborne radar can be used to evaluate the spatial and temporal homogeneity of the ground-based radar network.This paper focuses on comparing the PMR onboard the FY-3G satellite with S-band China New Generation Weather Radars(CINRADs).A comparison algorithm between the PMR and CINRADs has been developed,incorporating detailed quality control,attenuation correction,data optimization,spatiotemporal matching,non-uniform beam filling constraint,uniformity constraint,and frequency correction.The matched data in typical months of four seasons were selected to carry out the comparison.The data consistency between the PMR and CINRADs was analyzed.The correlation coefficient is 0.87,the deviation is 0.89 dB,and the standard deviation is 2.50 dB,based on 98226 matching samples.The results show the radar reflectivity of the PMR is quite comparable to that of the CINRADs,demonstrating that the PMR data quality is satisfactory and can be used to verify and correct data consistency among multiple ground-based radars.This work also paves the way for data fusion and joint application of satellite and ground radars in the future.展开更多
As investigated by 3GPP,support of UPF(user plane function)onboard satellite can reduce the latency of communications via satellite,and then it becomes a key enhancement in 5G network integrating with satellite commun...As investigated by 3GPP,support of UPF(user plane function)onboard satellite can reduce the latency of communications via satellite,and then it becomes a key enhancement in 5G network integrating with satellite communication.However,current 5G system cannot support UPF onboard LEO(low earth orbit)satellites,as it would face challenges like UPF mobility handling,synchronization between mobile network and satellite network,and condition of activating local data switching.To solve such challenges,this paper proposes a solution to support UPF onboard LEO satellite,which consists of enhanced network architecture,I-UPF(intermediate UPF)based local data switching scheme and communication latency based data path selection.We subsequently develop analytic models for performance evaluation and conduct simulations using the constellation configuration of iridium II.The simulation results show that the data switching via I-UPF onboard LEO satellite can reduce E2E(end to end)packet delivery latency and E2E packet loss ratio significantly compared with that of routing the data back to 5GC on the ground.The proposed scheme yet has increased signaling cost for handling UPF mobility.els,compared with existing similar companding algorithms.展开更多
文摘为研究科学有效的锂电池储能电站风险评估方法,从法律、法规、规程、标准和文献中提取并确定锂电池储能电站风险评价指标集,包括电池组、外部刺激、保护系统、运行环境、人为因素和安全管理等6个一级指标,以及电池基本情况、电池使用工况、电池模组状态等27个二级指标。采用序关系分析(G1)法确定指标主观权重,采用人工鱼群算法(artificial fish swarm algorithm,AFSA)确定各评价指标客观权重,采用乘积法确定最终的组合权重,结合云模型理论建立锂电池储能电站安全风险评价模型。以某电站为例开展研究,研究结果表明:储能电站风险综合期望值为61.382,风险处于较高水平,需采取适当措施进行风险防控。模型能够有效识别关键风险路径,评价结论与现场风险表现具有较高一致性。研究结果可为锂电池储能电站风险预防和管控提供参考。
文摘随着5G技术的广泛应用,用户通信需求和应用场景的日益复杂,对差异化的服务质量(QoS,Quality of Service)有了愈发严苛的要求。本研究提出了一种基于5G QoS标识(5G QoS Identifier,5QI)与无线频率选择优先级(RAT Frequency Selection Priority,RFSP)联合的动态调度策略,通过改进的加权比例公平(Weighted Proportional Fair,WPF)调度算法融合接入管理-策略控制功能(Access Management-Policy Control Function,AM-PCF)动态策略机制,实现用户级与业务级的资源灵活分配。设计分层分级网络保障模型,为不同用户分配差异化的5QI和RFSP调度权重。测试结果表明,保障用户平均速率、视频播放质量等关键性能均优于普通用户,验证了差异化调度策略在复杂场景下的有效性。
基金supported by grants from Natural Science Foundation of Jilin Province(No.23JQ08,No.YDZJ202502 CXJD077,No.JLARS-2025-0802-09 and No.YDZJ202501ZY TS706).
文摘As the aging population continues to grow,age-related health issues are becoming increasingly prominent,attracting widespread attention and concern from society.While research on the mechanisms of aging is relatively extensive,studies on the association between aging and related diseases remain limited.G.lucidum,a traditional medicinal fungus,has garnered significant attention due to its diverse bioactive properties.Recent studies have revealed that G.lucidum and its active components exhibit significant potential in anti-aging and regulating dysregulation of glucose and lipid metabolism.However,a comprehensive and detailed review of recent research findings has yet to be thoroughly explored.This paper summarizes and elucidates the latest advances in the pathological mechanisms of aging-related glucose and lipid metabolism disorders by retrieving data from databases such as X-mol and PubMed,provides a detailed account of the regulatory effects of G.lucidum’s primary active components on aging and lipid metabolism,and explores their potential mechanisms.Additionally,it discusses the application prospects of G.lucidum in the fields of anti-aging and metabolic regulation,aiming to provide a reference for research on aging-mediated lipid metabolism disorders and to lay a theoretical foundation for the further development and application of G.lucidum.
文摘Objective:To investigate the correlation between the expression of glucose-6-phosphate dehydrogenase(G6PD)and the clinicopathological characteristics,prognosis and immune cell infiltration of hepatocellular carcinoma(HCC).Methods:The expression of G6PD in liver cancer tissues and normal tissues is extracted from TCGA and GEO databases,validated by immunohistochemistry,and the correlation between G6PD expression and clinical features is analyzed.The clinical significance of G6PD in liver cancer is assessed by Kaplan-Meier,Cox regression,and prognostic line graph models.Functional enrichment analysis is performed by protein-protein interaction(PPI)network,GO/KEGG,GSEA and for G6PD-associated differentially expressed genes(DEGs).TIMER and ssGSEA packages are used to assess the correlation between expression and the level of immune cell infiltration.Results:Analysis of TCGA and GEO datasets revealed that G6PD expression is significantly upregulated in hepatocellular carcinoma tissues(P<0.001).G6PD expression is associated with histological grade,pathological stage,T-stage,vascular infiltration,and AFP level(P<0.05);HCC patients in the low G6PD expression group had longer overall survival and better prognosis compared with the high G6PD expression group(P<0.05).The level of G6PD expression affects the levels of macrophages,dendritic cells,B cells,and follicular helper T cells in the tumor microenvironment.Conclusion:High expression of G6PD is a potential biomarker for poor prognosis of hepatocellular carcinoma,and G6PD may be a target for immunotherapy of HCC.
基金jointly supported by the National Natural Science Foundation of China(Grant U2442214)the China Meteorological Administration Youth Innovation Team(Grant No.CMA2024QN10)+1 种基金the National Defense Science and Technology Bureau’s 14th Five-Year Civil Aerospace Preresearch Project(Grant Nos.D030303 and D040204)the International Space Water Cycle Observation Constellation Program(Grant No.183311KYSB20200015).
文摘China launched its first spaceborne Precipitation Measurement Radar(PMR)on the FY-3G satellite in April 2023.To achieve the scientific goal of measuring the three-dimensional precipitation structure,evaluating the quantitative measurement ability of the PMR is critical.China operates more than 250 weather radars over the mainland.Consistency of the spaceborne radar with ground-based radars will enhance precipitation measurement ability,especially over oceans and mountains where observations are sparse.Additionally,the spaceborne radar can be used to evaluate the spatial and temporal homogeneity of the ground-based radar network.This paper focuses on comparing the PMR onboard the FY-3G satellite with S-band China New Generation Weather Radars(CINRADs).A comparison algorithm between the PMR and CINRADs has been developed,incorporating detailed quality control,attenuation correction,data optimization,spatiotemporal matching,non-uniform beam filling constraint,uniformity constraint,and frequency correction.The matched data in typical months of four seasons were selected to carry out the comparison.The data consistency between the PMR and CINRADs was analyzed.The correlation coefficient is 0.87,the deviation is 0.89 dB,and the standard deviation is 2.50 dB,based on 98226 matching samples.The results show the radar reflectivity of the PMR is quite comparable to that of the CINRADs,demonstrating that the PMR data quality is satisfactory and can be used to verify and correct data consistency among multiple ground-based radars.This work also paves the way for data fusion and joint application of satellite and ground radars in the future.
基金supported by the national key research and development program of China under Grant 2020YFB1807901the National Science Foundation Project in China under grant 61931005.
文摘As investigated by 3GPP,support of UPF(user plane function)onboard satellite can reduce the latency of communications via satellite,and then it becomes a key enhancement in 5G network integrating with satellite communication.However,current 5G system cannot support UPF onboard LEO(low earth orbit)satellites,as it would face challenges like UPF mobility handling,synchronization between mobile network and satellite network,and condition of activating local data switching.To solve such challenges,this paper proposes a solution to support UPF onboard LEO satellite,which consists of enhanced network architecture,I-UPF(intermediate UPF)based local data switching scheme and communication latency based data path selection.We subsequently develop analytic models for performance evaluation and conduct simulations using the constellation configuration of iridium II.The simulation results show that the data switching via I-UPF onboard LEO satellite can reduce E2E(end to end)packet delivery latency and E2E packet loss ratio significantly compared with that of routing the data back to 5GC on the ground.The proposed scheme yet has increased signaling cost for handling UPF mobility.els,compared with existing similar companding algorithms.
