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基于UPLC-Orbitrap Fusion Lumos Tribrid-MS的女贞子酒蒸前后血清药物化学对比分析
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作者 刘昊霖 郑历史 +3 位作者 孙淑仃 赵迪 李焕茹 冯素香 《中华中医药学刊》 北大核心 2026年第1期175-186,I0027,共13页
目的基于超高效液相色谱-四极杆-静电场轨道阱-线性离子阱质谱法(ultra performance liquid chromatography-orbitrap fusion lumos tribrid-mass spectrometry,UPLC-Orbitrap Fusion Lumos Tribrid-MS)对大鼠灌胃女贞子、酒女贞子水提... 目的基于超高效液相色谱-四极杆-静电场轨道阱-线性离子阱质谱法(ultra performance liquid chromatography-orbitrap fusion lumos tribrid-mass spectrometry,UPLC-Orbitrap Fusion Lumos Tribrid-MS)对大鼠灌胃女贞子、酒女贞子水提液后血清中的移行成分进行对比分析。方法雄性Sprague-Dawley(SD)大鼠随机分为空白组、女贞子组(10.8 g·kg^(-1)·d^(-1))和酒女贞子组(10.8 g·kg^(-1)·d^(-1)),每组6只,给药组分别灌胃给予女贞子、酒女贞子水提液,空白组灌胃等体积纯净水,早晚各1次,连续5 d,末次给药1 h后腹主动脉取血,制备血清样品。采用Accucore^(TM) C_(18)(100 mm×2.1 mm,2.6μm)色谱柱,流动相为乙腈(A)-0.1%甲酸水(B),梯度洗脱(0~5 min,95%B→85%B;5~10 min,85%B→73%B;10~24 min,73%B→15%B),流速0.2 mL·min^(-1),进样量5μL,正、负离子模式扫描,扫描范围m/z 120~1200。采用Compound Discoverer 3.3软件,根据质谱数据和相关文献对女贞子、酒女贞子入血原型成分和代谢产物进行分析鉴定;采用多元统计分析方法对比女贞子、酒女贞子含药血清间的差异性成分。结果在给予女贞子水提液大鼠血清中共鉴定得到64个入血成分,包括40个原型成分和24个代谢产物;在给予酒女贞子水提液大鼠血清中共鉴定得到57个入血成分,包括35个原型成分和22个代谢产物。原型成分主要包括苯乙醇苷类、环烯醚萜类、三萜类、黄酮类等,代谢途径主要包括羟基化、甲基化、葡萄糖醛酸化等。根据变量重要性投影(variable importance in projection,VIP)值>1,t检验(Student's t test)结果P<0.05筛选出特女贞苷、女贞苷酸等12个差异性入血成分,其中7个原型成分、5个代谢产物。结论女贞子酒蒸后血清移行成分发生明显改变,可为阐明女贞子、酒女贞子药效物质基础提供理论依据。 展开更多
关键词 女贞子 炮制 血清药物化学 UPLC-Orbitrap fusion Lumos Tribrid-MS 多元统计分析
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Effects of CNTs Addition on Microstructure and Properties of Pure Copper Prepared by LPBF
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作者 Yang Laixia Zhang Longbo +4 位作者 Xie Qidong Zhang Yanze Yang Mengjia Mao Feng Chen Zhen 《稀有金属材料与工程》 北大核心 2026年第1期27-34,共8页
Copper manufactured by laser powder bed fusion(LPBF)process typically exhibits poor strength-ductility coordination,and the addition of strengthening phases is an effective way to address this issue.To explore the eff... Copper manufactured by laser powder bed fusion(LPBF)process typically exhibits poor strength-ductility coordination,and the addition of strengthening phases is an effective way to address this issue.To explore the effects of strengthening phases on Cu,Cu-carbon nanotubes(CNTs)composites were prepared using LPBF technique with Cu-CNTs mixed powder as the matrix.The formability,microstructure,mechanical properties,electrical conductivity,and thermal properties were studied.The result shows that the prepared composites have high relative density.The addition of CNTs results in inhomogeneous equiaxed grains at the edges of the molten pool and columnar grains at the center.Compared with pure copper,the overall mechanical properties of the composite are improved:tensile strength increases by 52.8%and elongation increases by 146.4%;the electrical and thermal properties are also enhanced:thermal conductivity increases by 10.8%and electrical conductivity increases by 12.7%. 展开更多
关键词 laser powder bed fusion(lpbf) Cu-CNTs composites mechanical property thermal conductivity
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Effect of Addition of Er-TiB_(2)Dual-Phase Nanoparticles on Strength-Ductility of Al-Mn-Mg-Sc-Zr Alloy Prepared by Laser Powder Bed Fusion
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作者 Li Suli Zhang Yanze +5 位作者 Yang Mengjia Zhang Longbo Xie Qidong Yang Laixia MaoFeng Chen Zhen 《稀有金属材料与工程》 北大核心 2026年第1期9-17,共9页
A dual-phase synergistic enhancement method was adopted to strengthen the Al-Mn-Mg-Sc-Zr alloy fabricated by laser powder bed fusion(LPBF)by leveraging the unique advantages of Er and TiB_(2).Spherical powders of 0.5w... A dual-phase synergistic enhancement method was adopted to strengthen the Al-Mn-Mg-Sc-Zr alloy fabricated by laser powder bed fusion(LPBF)by leveraging the unique advantages of Er and TiB_(2).Spherical powders of 0.5wt%Er-1wt%TiB_(2)/Al-Mn-Mg-Sc-Zr nanocomposite were prepared using vacuum homogenization technique,and the density of samples prepared through the LPBF process reached 99.8%.The strengthening and toughening mechanisms of Er-TiB_(2)were investigated.The results show that Al_(3)Er diffraction peaks are detected by X-ray diffraction analysis,and texture strength decreases according to electron backscatter diffraction results.The added Er and TiB_(2)nano-reinforcing phases act as heterogeneous nucleation sites during the LPBF forming process,hindering grain growth and effectively refining the grains.After incorporating the Er-TiB_(2)dual-phase nano-reinforcing phases,the tensile strength and elongation at break of the LPBF-deposited samples reach 550 MPa and 18.7%,which are 13.4%and 26.4%higher than those of the matrix material,respectively. 展开更多
关键词 Al-Mn-Mg-Sc-Zr alloy laser powder bed fusion nano-reinforcing phase synergistic enhancement
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Effect of Nb Addition on Tensile and Wear Properties of 18Ni300 Mold Steel Fabricated by LPBF
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作者 Jian Changhuang Yang Yang +5 位作者 Wang Chengyong Yu Bowen Niu Liuhui Hu Gaofeng Liu Jianye Huang Zhenghua 《稀有金属材料与工程》 北大核心 2026年第1期18-26,共9页
Laser powder bed fusion(LPBF)is highly suitable for forming 18Ni300 mold steel,thanks to its excellent capability in manufacturing complex shapes and outstanding capacity for regulating microstructures.It is widely us... Laser powder bed fusion(LPBF)is highly suitable for forming 18Ni300 mold steel,thanks to its excellent capability in manufacturing complex shapes and outstanding capacity for regulating microstructures.It is widely used in fields such as injection molding,die casting,and stamping dies.Adding reinforcing particles into steel is an effective means to improve its performance.Nb/18Ni300 composites were fabricated by LPBF using two kinds of Nb powders with different particle sizes,and their microstructures and properties were studied.The results show that the unmelted Nb particles are uniformly distributed in the 18Ni300 matrix and the grains are refined,which is particularly pronounced with fine Nb particles.In addition,element diffusion occurs between the particles and the matrix.The main phases of the base alloy are α-Fe and a small amount of γ-Fe.With the addition of Nb,part of the α-Fe is transformed into γ-Fe,and unmelted Nb phases appear.The addition of Nb also enhances the hardness and wear resistance of the composites but slightly reduces their tensile properties.After aging treatment,the molten pools and grain boundaries become blurred,grains are further refined,and the interfaces around the particles are thinned.The aging treatment also promotes the formation of reverted austenite.The hardness,ultimate tensile strength,and volumetric wear rate of the base alloy reach 51.9 HRC,1704 MPa,and 17.8×10^(-6) mm^(3)/(N·m),respectively.In contrast,the sample added with fine Nb particles has the highest hardness(56.1 HRC),ultimate tensile strength(1892 MPa)and yield strength(1842 MPa),and the volume wear rate of the sample added with coarse Nb particles is reduced by 90%to 1.7×10^(-6) mm^(3)/(N·m). 展开更多
关键词 laser powder bed fusion 18Ni300 mold steel Nb addition microstructure mechanical property
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Bearing Fault Diagnosis Based on Multimodal Fusion GRU and Swin-Transformer
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作者 Yingyong Zou Yu Zhang +2 位作者 Long Li Tao Liu Xingkui Zhang 《Computers, Materials & Continua》 2026年第1期1587-1610,共24页
Fault diagnosis of rolling bearings is crucial for ensuring the stable operation of mechanical equipment and production safety in industrial environments.However,due to the nonlinearity and non-stationarity of collect... Fault diagnosis of rolling bearings is crucial for ensuring the stable operation of mechanical equipment and production safety in industrial environments.However,due to the nonlinearity and non-stationarity of collected vibration signals,single-modal methods struggle to capture fault features fully.This paper proposes a rolling bearing fault diagnosis method based on multi-modal information fusion.The method first employs the Hippopotamus Optimization Algorithm(HO)to optimize the number of modes in Variational Mode Decomposition(VMD)to achieve optimal modal decomposition performance.It combines Convolutional Neural Networks(CNN)and Gated Recurrent Units(GRU)to extract temporal features from one-dimensional time-series signals.Meanwhile,the Markovian Transition Field(MTF)is used to transform one-dimensional signals into two-dimensional images for spatial feature mining.Through visualization techniques,the effectiveness of generated images from different parameter combinations is compared to determine the optimal parameter configuration.A multi-modal network(GSTCN)is constructed by integrating Swin-Transformer and the Convolutional Block Attention Module(CBAM),where the attention module is utilized to enhance fault features.Finally,the fault features extracted from different modalities are deeply fused and fed into a fully connected layer to complete fault classification.Experimental results show that the GSTCN model achieves an average diagnostic accuracy of 99.5%across three datasets,significantly outperforming existing comparison methods.This demonstrates that the proposed model has high diagnostic precision and good generalization ability,providing an efficient and reliable solution for rolling bearing fault diagnosis. 展开更多
关键词 MULTI-MODAL GRU swin-transformer CBAM CNN feature fusion
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Trajectory and influencing factors of changes in anxiety and depression in elderly patients after lumbar interbody fusion
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作者 Xiao-Feng Liu Yan-Hua Wu +4 位作者 Guang-Xi Huang Bin Yu Hui-Juan Xu Meng-Hua Qiu Lin Kang 《World Journal of Psychiatry》 2026年第1期312-321,共10页
BACKGROUND Lumbar interbody fusion(LIF)is the primary treatment for lumbar degenerative diseases.Elderly patients are prone to anxiety and depression after undergoing surgery,which affects their postoperative recovery... BACKGROUND Lumbar interbody fusion(LIF)is the primary treatment for lumbar degenerative diseases.Elderly patients are prone to anxiety and depression after undergoing surgery,which affects their postoperative recovery speed and quality of life.Effective prevention of anxiety and depression in elderly patients has become an urgent problem.AIM To investigate the trajectory of anxiety and depression levels in elderly patients after LIF,and the influencing factors.METHODS Random sampling was used to select 239 elderly patients who underwent LIF from January 2020 to December 2024 in Shenzhen Pingle Orthopedic Hospital.General information and surgery-related indices were recorded,and participants completed measures of psychological status,lumbar spine dysfunction,and quality of life.A latent class growth model was used to analyze the post-LIF trajectory of anxiety and depression levels,and unordered multi-categorical logistic regression was used to analyze the influencing factors.RESULTS Three trajectories of change in anxiety level were identified:Increasing anxiety(n=26,10.88%),decreasing anxiety(n=27,11.30%),and stable anxiety(n=186,77.82%).Likewise,three trajectories of change in depression level were identified:Increasing depression(n=30,12.55%),decreasing depression(n=26,10.88%),and stable depression(n=183,76.57%).Regression analysis showed that having no partner,female sex,elevated Oswestry dysfunction index(ODI)scores,and reduced 36-Item Short Form Health Survey scores all contributed to increased anxiety levels,whereas female sex,postoperative opioid use,and elevated ODI scores all contributed to increased depression levels.CONCLUSION During clinical observation,combining factors to predict anxiety and depression in post-LIF elderly patients enables timely intervention,quickens recovery,and enhances quality of life. 展开更多
关键词 Lumbar interbody fusion Elderly patients ANXIETY DEPRESSION Trajectory of change Influencing factors
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Cephalomedullary fusion nails for treatment of infected stemmed revision total knee arthroplasty:Four case reports
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作者 Gregory M Georgiadis Isaac A Arefi +3 位作者 Summer M Drees Ajay Nair Drew Wagner Austin C Lawrence 《World Journal of Orthopedics》 2026年第1期189-196,共8页
BACKGROUND Salvage of the infected long stem revision total knee arthroplasty is challenging due to the presence of well-fixed ingrown or cemented stems.Reconstructive options are limited.Above knee amputation(AKA)is ... BACKGROUND Salvage of the infected long stem revision total knee arthroplasty is challenging due to the presence of well-fixed ingrown or cemented stems.Reconstructive options are limited.Above knee amputation(AKA)is often recommended.We present a surgical technique that was successfully used on four such patients to convert them to a knee fusion(KF)using a cephalomedullary nail.CASE SUMMARY Four patients with infected long stem revision knee replacements that refused AKA had a single stage removal of their infected revision total knee followed by a KF.They were all treated with a statically locked antegrade cephalomedullary fusion nail,augmented with antibiotic impregnated bone cement.All patients had successful limb salvage and were ambulatory with assistive devices at the time of last follow-up.All were infection free at an average follow-up of 25.5 months(range 16-31).CONCLUSION Single stage cephalomedullary nailing can result in a successful KF in patients with infected long stem revision total knees. 展开更多
关键词 Knee fusion Knee arthrodesis Intramedullary nail Cephalomedullary nail Total knee infection Case report
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Identification of small impact craters in Chang’e-4 landing areas using a new multi-scale fusion crater detection algorithm
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作者 FangChao Liu HuiWen Liu +7 位作者 Li Zhang Jian Chen DiJun Guo Bo Li ChangQing Liu ZongCheng Ling Ying-Bo Lu JunSheng Yao 《Earth and Planetary Physics》 2026年第1期92-104,共13页
Impact craters are important for understanding the evolution of lunar geologic and surface erosion rates,among other functions.However,the morphological characteristics of these micro impact craters are not obvious an... Impact craters are important for understanding the evolution of lunar geologic and surface erosion rates,among other functions.However,the morphological characteristics of these micro impact craters are not obvious and they are numerous,resulting in low detection accuracy by deep learning models.Therefore,we proposed a new multi-scale fusion crater detection algorithm(MSF-CDA)based on the YOLO11 to improve the accuracy of lunar impact crater detection,especially for small craters with a diameter of<1 km.Using the images taken by the LROC(Lunar Reconnaissance Orbiter Camera)at the Chang’e-4(CE-4)landing area,we constructed three separate datasets for craters with diameters of 0-70 m,70-140 m,and>140 m.We then trained three submodels separately with these three datasets.Additionally,we designed a slicing-amplifying-slicing strategy to enhance the ability to extract features from small craters.To handle redundant predictions,we proposed a new Non-Maximum Suppression with Area Filtering method to fuse the results in overlapping targets within the multi-scale submodels.Finally,our new MSF-CDA method achieved high detection performance,with the Precision,Recall,and F1 score having values of 0.991,0.987,and 0.989,respectively,perfectly addressing the problems induced by the lesser features and sample imbalance of small craters.Our MSF-CDA can provide strong data support for more in-depth study of the geological evolution of the lunar surface and finer geological age estimations.This strategy can also be used to detect other small objects with lesser features and sample imbalance problems.We detected approximately 500,000 impact craters in an area of approximately 214 km2 around the CE-4 landing area.By statistically analyzing the new data,we updated the distribution function of the number and diameter of impact craters.Finally,we identified the most suitable lighting conditions for detecting impact crater targets by analyzing the effect of different lighting conditions on the detection accuracy. 展开更多
关键词 impact craters Chang’e-4 landing area multi-scale automatic detection YOLO11 fusion algorithm
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基于UPLC-Orbitrap Fusion Lumos Tribrid-MS、网络药理学与实验验证的正骨紫金丸活性成分及作用机制研究
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作者 冯志毅 孙淑仃 +3 位作者 郑历史 孙琪 刘泽 冯素香 《中国现代应用药学》 北大核心 2025年第21期3704-3716,共13页
目的基于UPLC-Orbitrap Fusion Lumos Tribrid-MS联合网络药理学与实验验证预测正骨紫金丸活血化瘀的活性成分及其作用机制。方法首先,采用UPLC-Orbitrap Fusion Lumos Tribrid-MS快速表征正骨紫金丸中的化学成分;其次,通过网络药理学... 目的基于UPLC-Orbitrap Fusion Lumos Tribrid-MS联合网络药理学与实验验证预测正骨紫金丸活血化瘀的活性成分及其作用机制。方法首先,采用UPLC-Orbitrap Fusion Lumos Tribrid-MS快速表征正骨紫金丸中的化学成分;其次,通过网络药理学的研究方法构建“药物-成分-靶点”网络,获取关键靶点及主要活性成分,结合String平台与CytoScape软件构建蛋白质-蛋白质相互作用(protein-protein interaction,PPI)网络,通过MateScape数据库富集分析通路,利用DiscoVery Studio 4.5软件进行分子对接验证;最后,建立急性软组织损伤动物模型,以急性软组织损伤评分与全血黏度为药效学指标开展药效学研究。结果正骨紫金丸中共鉴定出包括黄酮类、生物碱类、有机酸类和香豆素类等化合物67个,其中大黄素、藁本内酯、肉桂酸、水杨酸、芦荟大黄素可能为正骨紫金丸活血化瘀的主要活性成分。PPI网络拓扑分析得到TNF、ALB、AKT1等26个核心靶点,KEGG富集分析表明正骨紫金丸主要通过调控TNF、PI3K-Akt、NF-κB等信号通路发挥活血化瘀作用,分子对接结果显示正骨紫金丸主要活性成分与关键靶点结合良好,药效学结果表明正骨紫金丸可显著降低急性软组织损伤大鼠的全血黏度。结论本研究明确了正骨紫金丸活血化瘀的活性成分和作用机制,同时表明其可能通过作用于多靶点、多通路整体调节,共同发挥活血化瘀作用,为其后续深入研究提供参考。 展开更多
关键词 正骨紫金丸 UPLC-Orbitrap fusion Lumos Tribrid-MS 成分分析 网络药理学 活血化瘀
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基于Clickteam Fusion的HDB3/AMI编译码实验教学软件设计
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作者 张春光 《电脑编程技巧与维护》 2025年第1期31-34,共4页
论文阐述了一种利用Clickteam Fusion引擎进行HDB3/AMI编译码实验仿真的编程方法。利用计算机技术开发的该仿真实验富有一定的真实感,可直接在计算机上模拟操作。通过学生自主操作,使其掌握光纤实验基本原理,记忆并理解相关操作知识,有... 论文阐述了一种利用Clickteam Fusion引擎进行HDB3/AMI编译码实验仿真的编程方法。利用计算机技术开发的该仿真实验富有一定的真实感,可直接在计算机上模拟操作。通过学生自主操作,使其掌握光纤实验基本原理,记忆并理解相关操作知识,有效提高实验学习效率。 展开更多
关键词 HDB3/AMI编译码实验 仿真 Clickteam fusion引擎
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基于逐块有限元方法TA15钛合金LPBF成形应力与变形模拟及试验研究
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作者 张晓杭 黄雪莹 +4 位作者 冉兴 王哲 唐诚江 徐伟 路新 《铸造》 2025年第11期1464-1475,共12页
为实现TA15钛合金激光粉末床熔融(LPBF)成形过程中的应力与变形精确控制,提升高性能件的制造质量,提出了一种基于热-力间接耦合的改进型逐块有限元模型,并从工艺参数、扫描策略、支撑结构等多个维度进行了系统模拟分析与试验验证。结果... 为实现TA15钛合金激光粉末床熔融(LPBF)成形过程中的应力与变形精确控制,提升高性能件的制造质量,提出了一种基于热-力间接耦合的改进型逐块有限元模型,并从工艺参数、扫描策略、支撑结构等多个维度进行了系统模拟分析与试验验证。结果表明,相较于传统逐点模型,逐块模型温度与应力场计算耗时缩减了56%~83%,模拟结果误差控制在5%以内;相较于逐层模型,逐块模型保证了温度与应力场的模拟精度。此外,不同成形参量下最大残余应力和最大变形量的预测值与试验值也较为接近。研究成果为LPBF成形钛合金复杂零件的应力/变形调控和高质量制造设计提供了理论依据。 展开更多
关键词 TA15钛合金 激光粉末床熔融(lpbf) 逐块有限元法 残余应力 变形
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基于UPLC-Orbitrap Fusion Lumos Tribrid-MS的女贞子不同炮制品血中移行成分分析
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作者 夏仪 孙淑仃 +3 位作者 郑历史 赵迪 李焕茹 冯素香 《中药材》 北大核心 2025年第3期606-615,共10页
目的:研究大鼠灌胃给药醋蒸女贞子、盐蒸女贞子、清蒸女贞子后血清中的移行成分并对其进行对比分析。方法:采用UPLC-Orbitrap Fusion Lumos Tribrid-MS技术,结合Xcalibur和Compound Discoverer软件,根据保留时间、精确分子量、二级碎片... 目的:研究大鼠灌胃给药醋蒸女贞子、盐蒸女贞子、清蒸女贞子后血清中的移行成分并对其进行对比分析。方法:采用UPLC-Orbitrap Fusion Lumos Tribrid-MS技术,结合Xcalibur和Compound Discoverer软件,根据保留时间、精确分子量、二级碎片信息及文献报道,鉴定女贞子不同炮制品的入血成分。基于主成分分析(PCA)和正交偏最小二乘判别分析(OPLS-DA)筛选女贞子不同炮制品含药血清的差异性成分。结果:共鉴定出95个入血成分,其中共有成分89个,醋蒸女贞子特有成分2个、盐蒸女贞子特有成分3个、清蒸女贞子特有成分1个。入血成分包含61个原型成分和34个代谢产物,原型成分主要包括苯乙醇类、环烯醚萜苷类、黄酮类化合物,代谢产物主要涉及羟基化、葡萄糖醛酸化、硫酸酯化反应等。PCA、OPLS-DA结果表明女贞子不同炮制品血中移行成分存在明显差异,OPLS-DA筛选出27个差异性成分。结论:该研究初步阐明了醋蒸女贞子、盐蒸女贞子、清蒸女贞子在大鼠血清中移行成分的差异,为进一步明确女贞子不同炮制品的药效物质基础提供了依据。 展开更多
关键词 女贞子 炮制 血清药物化学 UPLC-Orbitrap fusion Lumos Tribrid-MS 多元统计分析
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短时时效优化LPBF成形AlMgScZr合金的强度-塑性协同效应
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作者 杨胶溪 田育金 +2 位作者 吴迪 高枫 李怀学 《光学学报(网络版)》 2025年第22期57-66,共10页
针对激光粉末床熔融(LPBF)制备的高强度AlMgScZr合金,系统研究了直接时效工艺对其力学性能的优化作用。通过对比不同时效温度(300~325℃)和时效时间(0.5~4 h)的影响,发现短时(30~45 min)时效处理可显著提升AlMgScZr合金的综合性能。在32... 针对激光粉末床熔融(LPBF)制备的高强度AlMgScZr合金,系统研究了直接时效工艺对其力学性能的优化作用。通过对比不同时效温度(300~325℃)和时效时间(0.5~4 h)的影响,发现短时(30~45 min)时效处理可显著提升AlMgScZr合金的综合性能。在325℃下时效处理30 min,合金的Z向抗拉强度达到(582±4.32)MPa,同时保持11.30%±0.31%的延伸率,实现了强度与塑性的最佳协同。微观组织分析表明,短时时效有效促进了细小、弥散Al3(Zr,Sc)析出相的形成,避免了长时时效导致的析出相粗化及塑性劣化问题。此外,短时工艺显著降低了能耗与热变形风险,为航空航天轻量化关键部件的增材制造提供了高效、可靠的性能调控策略。 展开更多
关键词 增材制造 激光粉末床熔融 AlMgScZr合金 短时时效处理 力学性能
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LPBF成形GH4099直接时效热处理工艺优化研究
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作者 韩思雨 王玉健 +2 位作者 申红斌 步贤政 王志敏 《航天制造技术》 2025年第1期43-49,共7页
本文旨在探讨直接时效温度和时间对沉积态GH4099合金中γ′强化相析出行为及其对合金显微硬度和力学性能的影响,并通过调控直接时效温度和时间优化γ′强化相的析出,从而提高合金的性能。采用不同直接时效温度(700℃、750℃、800℃、850... 本文旨在探讨直接时效温度和时间对沉积态GH4099合金中γ′强化相析出行为及其对合金显微硬度和力学性能的影响,并通过调控直接时效温度和时间优化γ′强化相的析出,从而提高合金的性能。采用不同直接时效温度(700℃、750℃、800℃、850℃)和不同直接时效时间(0.5 h、1 h、2 h、4 h、8 h、10 h、12 h、16 h)处理沉积态GH4099合金,利用扫描电子显微镜和Image-Pro Plus软件分析γ′强化相的尺寸、数量和形态。同时,通过Lifshitz-Slyozov-Wagner(LSW)方程计算γ′强化相粒子的粗化速率,并测试了合金试样和试棒的显微硬度和力学性能。研究结果表明,随着直接时效的进行,γ′强化相聚集长大,沉积态GH4099由欠时效状态逐渐转变为过时效状态,750℃×4 h处理后显微硬度值最高,为458.27HV0.5,此外研究发现,提高时效温度,可以改善GH4099的塑性,850℃处理时GH4099的断后延伸率最高,约为26%。 展开更多
关键词 lpbf GH4099 直接时效 工艺优化
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Tailoring nanoscale primary silicon in laser powder bed fusion for high-performance lithium-ion battery anodes 被引量:1
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作者 Li Cao Min Zheng +3 位作者 Guochen Dong Jiejie Xu Rongshi Xiao Ting Huang 《Journal of Materials Science & Technology》 2025年第8期278-287,共10页
Silicon-based anodes,utilizing nanosized silicon materials,hold great promise for the next-generation of lithium-ion batteries due to their high capacity and stable expansion.This study aims to address challenges in t... Silicon-based anodes,utilizing nanosized silicon materials,hold great promise for the next-generation of lithium-ion batteries due to their high capacity and stable expansion.This study aims to address challenges in traditional slurry-coated anodes,such as agglomeration and low adhesive strength,through the application of laser powder bed fusion(LPBF).The process involves fabricating an Al-Si-Cu alloy layer on a Cu foil current collector,followed by dealloying to create a porous Si-Cu anode.Simulated and experimental results demonstrate successful alloy layer formation through optimized laser spot(55μm)and powder sizes(1-5μm).Controlled cooling produces primary Si particles ranging from 150 nm to 1μm.The resulting microstructure enhances electrochemical performance,particularly by tailoring the size of primary Si.The resultant porous Si-Cu anode,featuring uniformly distributed primary Si(200 nm)metallurgically bonded with Cu networks,exhibits an initial coulombic efficiency of 83% and a remarkable capacity retention of 80% after 300 cycles at 2 C.In-situ and ex-situ observations confirm the crucial role of anode architecture in performance enhancement.This study elucidates the influence of the LPBF microstructure on anode performance and broadens the potential application of laser powder bed fusion in battery manufacturing. 展开更多
关键词 lpbf DEALLOYING Primary Si Microstructure LIBS
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Hot Isostatic Pressing for Enhancing Mechanical Properties of Mo Alloys Prepared by Laser Powder Bed Fusion 被引量:1
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作者 Liang Xunwen Fu Zhongxue +3 位作者 Zhang Shiming Che Yusi Cheng Pengming Wang Pei 《稀有金属材料与工程》 北大核心 2025年第3期587-592,共6页
To enhance the mechanical properties of Mo alloys prepared through laser powder bed fusion(LPBF),a hot isostatic pressing(HIP)treatment was used.Results show that following HIP treatment,the porosity decreases from 0.... To enhance the mechanical properties of Mo alloys prepared through laser powder bed fusion(LPBF),a hot isostatic pressing(HIP)treatment was used.Results show that following HIP treatment,the porosity decreases from 0.27%to 0.22%,enabling the elements Mo and Ti to diffuse fully and to distribute more uniformly,and to forming a substantial number of low-angle grain boundaries.The tensile strength soars from 286±32 MPa to 598±22 MPa,while the elongation increases from 0.08%±0.02%to 0.18%±0.02%,without notable alterations in grain morphology during the tensile deformation.HIP treatment eliminates the molten pool boundaries,which are the primary source for premature failure in LPBFed Mo alloys.Consequently,HIP treatment emerges as a novel and effective approach for strengthening the mechanical properties of LPBFed Mo alloys,offering a fresh perspective on producing high-performance Mo-based alloys. 展开更多
关键词 Mo alloys hot isostatic pressing laser powder bed fusion mechanical properties
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Laser powder bed fusion of WE43 magnesium alloy with superior balance of strength and ductility
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作者 Wenhe Xu Jikang Li +7 位作者 Zhenwu Zhang Hongwei Yuan Guojin An Hai Shi Chao Cai Wenming Jiang Wei Li Qingsong Wei 《Journal of Magnesium and Alloys》 2025年第3期1275-1293,共19页
WE43 is a high-strength magnesium alloy containing rare-earth elements such as Y,Gd and Nd.Nevertheless,how to further obtain the balance of strength and ductility,as well as the manufacture of complex structures is s... WE43 is a high-strength magnesium alloy containing rare-earth elements such as Y,Gd and Nd.Nevertheless,how to further obtain the balance of strength and ductility,as well as the manufacture of complex structures is still a dilemma for its engineering application.In this study,WE43 alloy samples withfine microstructures,high densification and excellent mechanical properties were successfully prepared by laser powder bed fusion(LPBF)additive manufacturing.The optimal process window was established,and the formation mechanisms of three types of porosity defects were revealed,namely lack-of-fusion pores,meltfluctuation-induced pores,and keyhole-induced pores.With the combined process of laser power of 200 W and scanning speed of 600 mm/s,samples with a high density of 99.89%were obtained.Furthermore,periodic heterogeneous microstructure was prepared along the build direction,i.e.,fine grains(∼4.1μm)at melt pool boundaries and coarse grain(∼23.6μm)inside melt pool.This was mainly due to the preferential precipitation of Zr and Mg_(3)(Gd,Nd)nano-precipitates at the melt pool boundaries providing nucleation sites for the grains.This special feature could provide an extra hetero-deformation induced(HDI)strengthening and retard fracture.The optimal tensile yield strength,ultimate tensile strength and elongation at break were 276±1 MPa,292±1 MPa and 6.1±0.2%,respectively.The obtained tensile properties were superior to those of other magnesium alloys and those fabricated by other processes.The solid solution strengthening(∼24.5%),grain boundary strengthening(∼14.4%)and HDI strengthening(∼32.2%)were the main sources of high yield strength.This work provides a guidance on studying the pore defect suppression and strengthening mechanisms of WE43 alloy and other magnesium alloys produced by LPBF. 展开更多
关键词 Laser powder bed fusion(lpbf) WE43 alloy Pore defect Microstructure Strengthening mechanisms
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Laser powder bed fusion of Mg-6Gd-3Y-0.2Zr alloy:Excellent printability,heterogeneous microstructure and dedicated direct aging heat treatment
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作者 Qingchen Deng Jing Luo +9 位作者 Ziyi Liu Qianye Wu Dazhi Liu Lianmei Wu Fei Li Manman Yi Penghuai Fu Yujuan Wu Liming Peng Wenjiang Ding 《Journal of Magnesium and Alloys》 2025年第10期4891-4911,共21页
As a universal casting Mg-RE alloy,Mg-6Gd-3Y-Zr(GW63K,wt.%)alloy exhibits superior strength-ductility synergy and holds significant potential for engineering applications.In this study,the GW63K alloy is produced usin... As a universal casting Mg-RE alloy,Mg-6Gd-3Y-Zr(GW63K,wt.%)alloy exhibits superior strength-ductility synergy and holds significant potential for engineering applications.In this study,the GW63K alloy is produced using the laser powder bed fusion(LPBF)additive manufacturing(AM)process for the first time.The printability,microstructure characteristics,and post-heat treatment conditions of the GW63K alloy are systematically investigated.The as-built GW63K samples demonstrate high relative densities exceeding 99.6%and exhibit no macroscopic and microscopic cracking across a wide range of process parameters,indicating excellent printability.An exceptional heterogeneous microstructure is observed in the as-built GW63K alloy,comprising coarse columnar grains,fine equiaxed grains with an average grain size of 21.72μm,uniformly distributed nano-sized Mg_(24)(Gd,Y)_(5)secondary phase,and numerous dislocations.Consequently,the as-built GW63K alloy displays enhanced tensile strengths and ductility compared to the as-cast alloy,with yield strength(YS),ultimate tensile strength(UTS)and elongation(EL)values of 218±4 MPa,284±5 MPa and 11.9±1.6%respectively.Additionally,due to the absence of coarse micron-sized secondary phase,a specific direct aging(T5)heat treatment regime at 200℃for 128 h is optimized for the as-built GW63K alloy to introduce dense and dispersedβ’aging precipitates.This T5 treatment surpasses the conventional solution plus aging(T6)heat treatment in enhancing mechanical properties.The LPBF-T5 GW63K alloy exhibits YS,UTS and EL values of 293±6 MPa,359±4 MPa and 2.9±0.7%,respectively.Notably,the YS of the LPBF-T5 alloy represents the highest value for the GW63K alloy,even surpassing that of the extrusion-T5 alloy.This study indicates that the GW63K alloy is a highly promising material for manufacturing near-net-shape high-strength Mg alloy components with intricate geometries using LPBF. 展开更多
关键词 Laser powder bed fusion(lpbf) Mg-Gd-Y-Zr alloy PRINTABILITY Heterogeneous microstructure Direct aging heat treatment
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Enhanced processability and mechanical properties of poly-ether-ether-ketone/nano-silicon nitride composite scaffolds fabricated by laser powder bed fusion
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作者 Haoze Wang Peng Chen +5 位作者 Jin Su Yuxin Li Yuheng Tian Leiyi Qi Chunze Yan Yusheng Shi 《Journal of Materials Science & Technology》 2025年第26期296-308,共13页
Poly-ether-ether-ketone/nano-silicon nitride(PEEK/nSN)composite scaffolds,fabricated by laser powder bed fusion(LPBF),show great potential for orthopedic applications due to their excellent biological performance and ... Poly-ether-ether-ketone/nano-silicon nitride(PEEK/nSN)composite scaffolds,fabricated by laser powder bed fusion(LPBF),show great potential for orthopedic applications due to their excellent biological performance and mechanical adaptability.However,the effect of nSN on LPBF processability and scaffold properties remains unclear.This study systematically investigates the processability and mechanical per-formance of PEEK/nSN composites to enable reliable clinical fabrication.The results show that adding nSN improves powder flowability and inhibits crystallization,enhancing LPBF processability.The introduction of nSN reduces PEEK’s non-isothermal crystallization Avrami exponent from 3.04 to 2.01,suggesting a transformation from a three-dimensional spherulitic to a two-dimensional lamellar crystal structure.Tensile tests reveal that the presence of nSN alters the optimal process parameters,reducing the optimal laser power from 25 W to 22 W due to increased energy absorption efficiency,as shown by an increase in absorbance at 843 cm^(-1)from 0.27 to 0.35 as the nSN content increases to 2 wt%.Porous diamond-structured scaffolds were fabricated using optimal parameters for pure PEEK,PEEK/1 wt%nSN,and PEEK/2 wt%nSN.Diamond-structured scaffolds fabricated with 1 wt%nSN showed a 12.2%increase in elastic modulus compared to pure PEEK,highlighting the enhanced mechanical performance.Over-all,this study offers key insights into the stable and customizable LPBF fabrication of PEEK/nSN porous scaffolds,providing a foundation for future research on their bioactivity and antibacterial properties for orthopedic applications. 展开更多
关键词 Poly-ether-ether-ketone(peek) Nano-silicon nitride(nsn) Composite Laser powder bed fusion(lpbf) Scaffold
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Effect of CNT content on microstructure and tribological properties of CNTs/AlSi10Mg composites by LPBF
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作者 Li-yi Jiang Chao-yi Shen +6 位作者 Ting-ting Liu Chang-dong Zhang Xiang Su Wei-wei Xu Bo-xiang Wang Zhi-xiang Qi Wen-he Liao 《China Foundry》 2025年第4期439-448,共10页
In this study,carbon nanotubes(CNTs)/AlSi10Mg composite parts with CNTs contents ranging from 0.0 to 2.0wt.%were successfully fabricated via laser powder bed fusion(LPBF)with laser scan speeds ranging from 900 to 1,90... In this study,carbon nanotubes(CNTs)/AlSi10Mg composite parts with CNTs contents ranging from 0.0 to 2.0wt.%were successfully fabricated via laser powder bed fusion(LPBF)with laser scan speeds ranging from 900 to 1,900 mm·s^(-1).Uniform dispersion of CNTs in the powders can be achieved when their content is below 2.0wt.%.In the LPBF samples,the morphology of the CNTs is found to be directly related to their content.Especially,the length of CNTs in samples prepared by LPBF increases as the CNT content increases.The length of CNTs is approximately 200-300 nm in the 1.0wt.%CNTs/AlSi10Mg composites and approximately 500-1,000 nm in the 2.0wt.%CNTs/AlSi10Mg composites.The hardness of the composites reaches its highest value of 143.3 HV when the CNTs content is 1.0wt.%and the laser scan speed is 1,300 mm·s^(-1).It is found that the self-lubricating properties of the CNTs improve the tribological properties of the composites.The coefficient of friction(CoF)and wear rate of the samples decrease with increasing CNT content.At a CNTs content of 2.0wt.%,the CoF and wear rate of the composite decrease by approximately 14%and 30%,respectively,compared to the unreinforced matrix.The presence of CNTs leads to a more complete and refined network microstructure within the samples.Both the CNTs and the aluminum carbide contribute to the Orowan mechanism and the Hall-Petch effect within the matrix. 展开更多
关键词 carbon nanotubes(CNTs) aluminum matrix composites laser powder bed fusion(lpbf) HARDNESS coefficient of friction(CoF)
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