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STUDIES ON CHITOSAN AND ITS pH-RESPONSIBILITY 被引量:1
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作者 Sun Duoxian,Wu Shuizhu(Department of Applied ChemistryTianjin University,Tianjin, 300072,China) 《Chinese Journal of Biomedical Engineering(English Edition)》 1994年第1期28-34,共7页
This article is mainly concerned with speCial runctional membranes prepared from chitin, chitosan and surface poly(acrylic acid)-grarted chitin and their pHstimullus respensibility. The results showed that the Permeat... This article is mainly concerned with speCial runctional membranes prepared from chitin, chitosan and surface poly(acrylic acid)-grarted chitin and their pHstimullus respensibility. The results showed that the Permeation or NaCl moleculesthrough the membranes were controlled by changing the pH or the membranes reyersiblyand the pH responsibility or chitosan membrane is quite oppposite or the surface poly(acrylic acid)-grarted chitin. 展开更多
关键词 Chitosan/Chitin funcional membranes pHresponsibility MATERIAL
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Improved spontaneous erectile function in men with mild-tomoderate arteriogenic erectile dysfunction treated with a nightly dose of sildenafil for one year: a randomized trial 被引量:12
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作者 Frank Sommer Theodor Klotz Udo Engelmann 《Asian Journal of Andrology》 SCIE CAS CSCD 2007年第1期134-141,共8页
Aim: To test the hypothesis that sildenafil (50 mg nightly for one year) can improve spontaneous erectile function (EF) in men with mild-to-moderate arteriogenic erectile dysfunction (ED) responsive to erectoge... Aim: To test the hypothesis that sildenafil (50 mg nightly for one year) can improve spontaneous erectile function (EF) in men with mild-to-moderate arteriogenic erectile dysfunction (ED) responsive to erectogenic treatment. Methods: In a prospective open-label trial, 112 men with ED were randomized to sildenafil 50 mg nightly or sildenafil 50 or 100 mg as needed for 12 months, followed by one-month and 6-month non-medicated periods. Non-randomized, non-medicated men with ED were also assessed. The EF domain of the International Index of Erectile Function (IIEF EF) and the peak systolic velocity (PSV) of penile cavernous arteries were used to measure the efficacy. Results: After sildenafil treatment and a subsequent non-medicated month, IIEF EF was normal in 29 of 48 (60.4%, 95% confidence interval [CI]: 45.3-74.2%) of the nightly group vs. 4 of 49 (8.2%, 95% CI: 2.3-19.6%) of the as-needed group. PSV improved by 11.2 cm/s (95% CI: 4.7-21.4; P = 0.012) in the nightly group but only by 3.4 cm/s (-5.1- 14.7; P = 0.435) in the as-needed group. IIEF EF normalized in 1 of 18 (5.6%, 95% CI: 0.1-27.3%) non-medicated men and the PSV declined slightly. Six months after treatment, the IIEF EF remained normal and PSV was stabilized in most (28/29, 97%) nightly group men who had initially normalized. Conclusion: Sildenafil nightly for one year resulted in ED regression that persisted well beyond the end of treatment, so that spontaneous EF was characterized as normal on the IIEF in most men. The results from this open-label, randomized trial warrant verification under double-blind, placebo-controlled conditions. 展开更多
关键词 PHOSPHODIESTERASE sexual dysfunctions PSYCHOLOGICAL sildenafil citrate erectile funcion
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Stability Analysis of Continuous-Time Fuzzy Large-Scale System
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作者 曾怡达 张友刚 肖建 《Journal of Southwest Jiaotong University(English Edition)》 2003年第2期144-151,共8页
A continuous-time fuzzy large-scale system F consists of some interconnected Takagi-Sugeno fuzzy subsystems. Two sufficient conditions for the asymptotic stability of this system (namely, theorem 1 and theorem 2) are... A continuous-time fuzzy large-scale system F consists of some interconnected Takagi-Sugeno fuzzy subsystems. Two sufficient conditions for the asymptotic stability of this system (namely, theorem 1 and theorem 2) are derived via a multiple Lyapunov function approach. In theorem 1, the information of membership functions of fuzzy rules should be known in order to analyze the stability of F. But in general this information is not easy to be acquired for their time-varying property. So theorem 2 is provided to judge the asymptotic stability of F, based on which there is no need to know the information of membership functions in stability analysis. Finally, a numerical example is given to show the utility of the method proposed in this paper. 展开更多
关键词 fuzzy large-scale system stability analysis Takagi-Sugeno fuzzy model multiple Lyapunov funcion
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