Objective:To study the effect of fumigation and washing with Shujin Huoluo Decoction combined with Duhuo Parasitic Decoction on Metalloproteinase inhibitor-1(TIMP-1)and Oxyphosphatase 1,PON1)level.Methods:A total of 1...Objective:To study the effect of fumigation and washing with Shujin Huoluo Decoction combined with Duhuo Parasitic Decoction on Metalloproteinase inhibitor-1(TIMP-1)and Oxyphosphatase 1,PON1)level.Methods:A total of 100 KOA patients,59 males and 41 females,were selected for diagnosis and treatment in our hospital from November 2018 to November 2019.The patients were divided into the control group and the combined group with 50 patients each according to a completely random method.The control group was treated with Duhuo Parasitic Decoction and the combined group was treated with Duhuo Parasitic Decoction and Shujinhuoluo decoction.Detection of TIMP-1,PON1,Matrix metalloproteinase-3(MMP-3),C-reactive protease(CRP),Tumor necrosis factor-alpha(TNF-α)and Superoxide dismutase(SOD)levels.WOMAC score,Lysholm score,and VAS score were evaluated.Results:The levels of TIMP-1 and PON1 in the combined group were higher than those in the control group after treatment,and the levels of MMP-3 were lower than those in control group(P<0.05).The WOMAC score and VAS score of the combined group were lower than those of the control group,and the Lysholm score was higher than that of control group(P<0.05).The levels of CRP and TNF-αin the combined group were lower than those in the control group,and the SOD levels were higher than those in control group(P<0.05).The total effective rate of the combined group was higher than the total effective rate of control group(P<0.05).Conclusion:The combination of fumigation and washing with Shujin Huoluo Decoction and Duhuo Parasitic Decoction has a significant effect on the treatment of KOA patients.It improves the levels of TIMP-1 and PON1,improves the knee function of patients and pain.展开更多
Objective: to analyze the effect of Haitongpi decoction fumigation and washing on the postoperative rehabilitation of metacarpal and phalangeal fractures. Methods: a total of 70 patients with metacarpal and phalangeal...Objective: to analyze the effect of Haitongpi decoction fumigation and washing on the postoperative rehabilitation of metacarpal and phalangeal fractures. Methods: a total of 70 patients with metacarpal and phalangeal fractures in our hospital from January 2019 to January 2020 were selected and randomly divided into two groups with 35 cases in each group. The patients in the control group were given conventional rehabilitation therapy, while the patients in the observation group were given conventional rehabilitation therapy combined with Haitongpi Decoction fumigation and washing therapy. The hospital stay, healing time of metacarpal and phalangeal fractures, pain degree before and after treatment and total effective rate and washing of the two groups were compared. Results: the hospital stay and the healing time of metacarpal and phalangeal fractures in the observation group were shorter than those in the control group. The visual analogue pain score of the patients after treatment was lower than that in the control group, and the total effective rate was higher than that in the control group (P < 0.05). Conclusion: Haitongpi Decoction is effective in postoperative rehabilitation of metacarpal and phalangeal fractures, which can reduce pain, accelerate fracture healing and shorten hospital stay.展开更多
基金Health and Planning Commission of Guangxi Zhuang Autonomous Region(No.Z20170705)
文摘Objective:To study the effect of fumigation and washing with Shujin Huoluo Decoction combined with Duhuo Parasitic Decoction on Metalloproteinase inhibitor-1(TIMP-1)and Oxyphosphatase 1,PON1)level.Methods:A total of 100 KOA patients,59 males and 41 females,were selected for diagnosis and treatment in our hospital from November 2018 to November 2019.The patients were divided into the control group and the combined group with 50 patients each according to a completely random method.The control group was treated with Duhuo Parasitic Decoction and the combined group was treated with Duhuo Parasitic Decoction and Shujinhuoluo decoction.Detection of TIMP-1,PON1,Matrix metalloproteinase-3(MMP-3),C-reactive protease(CRP),Tumor necrosis factor-alpha(TNF-α)and Superoxide dismutase(SOD)levels.WOMAC score,Lysholm score,and VAS score were evaluated.Results:The levels of TIMP-1 and PON1 in the combined group were higher than those in the control group after treatment,and the levels of MMP-3 were lower than those in control group(P<0.05).The WOMAC score and VAS score of the combined group were lower than those of the control group,and the Lysholm score was higher than that of control group(P<0.05).The levels of CRP and TNF-αin the combined group were lower than those in the control group,and the SOD levels were higher than those in control group(P<0.05).The total effective rate of the combined group was higher than the total effective rate of control group(P<0.05).Conclusion:The combination of fumigation and washing with Shujin Huoluo Decoction and Duhuo Parasitic Decoction has a significant effect on the treatment of KOA patients.It improves the levels of TIMP-1 and PON1,improves the knee function of patients and pain.
文摘Objective: to analyze the effect of Haitongpi decoction fumigation and washing on the postoperative rehabilitation of metacarpal and phalangeal fractures. Methods: a total of 70 patients with metacarpal and phalangeal fractures in our hospital from January 2019 to January 2020 were selected and randomly divided into two groups with 35 cases in each group. The patients in the control group were given conventional rehabilitation therapy, while the patients in the observation group were given conventional rehabilitation therapy combined with Haitongpi Decoction fumigation and washing therapy. The hospital stay, healing time of metacarpal and phalangeal fractures, pain degree before and after treatment and total effective rate and washing of the two groups were compared. Results: the hospital stay and the healing time of metacarpal and phalangeal fractures in the observation group were shorter than those in the control group. The visual analogue pain score of the patients after treatment was lower than that in the control group, and the total effective rate was higher than that in the control group (P < 0.05). Conclusion: Haitongpi Decoction is effective in postoperative rehabilitation of metacarpal and phalangeal fractures, which can reduce pain, accelerate fracture healing and shorten hospital stay.
