In order to systematically investigate the chemical constituents of Citri Reticulatae Folium (leaves of 'Fuju'), an analytical method that included high-performance liquid chromatography, diode array detection, el...In order to systematically investigate the chemical constituents of Citri Reticulatae Folium (leaves of 'Fuju'), an analytical method that included high-performance liquid chromatography, diode array detection, electrospray ionization, and ion-trap time-of-flight mass spectrometry (HPLC-DAD-ESI-MSn) was used to separate and identify the individual chemical components of Citri Reticulatae Folium. As a result, 96 compounds were tentatively identified in this study: including 31 phenolic acids, 4 flavonoid aglycones, 6 flavonoid mono-O-glycosides, 10 flavonoid-O-diglycosides, 5 flavonoid mono-C-glycosides, 5 flavonoid di-C-glycosides, 6 flavonoid O,C-glycosides, 5 (3-hydroxy-3-methylglutaryl) glycosyl flavonoids, 1 flavan-3-ol, and 2 alkaloids. In addition, 21 polymethoxy flavonoids (PMFs) were identified in this paper. Among these compounds, 52 compounds, which were previously found in other Citrus plants, have been identified for the first time in Citri Reticulatae Folium. 15 compounds have not been previously found in the Citrus genus were identified. Moreover, 9 potentially new compounds have also been detected in this paper. This is the first report of the full characterization of chemical components of Citri Reticulatae Folium (leaves of'Fuju') by HPLC-DAD-ESI-MSn.展开更多
When Dachung Wochen,a 35-year-old blind Tibetan,walks in the bustling streets of Lhasa,capital of the Xizang Autonomous Region,with his guide dog Fuju,people are amazed by their tacit cooperation.Fuju helps his master...When Dachung Wochen,a 35-year-old blind Tibetan,walks in the bustling streets of Lhasa,capital of the Xizang Autonomous Region,with his guide dog Fuju,people are amazed by their tacit cooperation.Fuju helps his master navigate every obstacle on the road.After spending only a year with him,he understands most of his commands in Tibetan.Dachung Wochen's journey with the four-year-old canine began in April 2024.After 28 days of professional training at the China Guide Dog Training Center in Dalian,Liaoning Province,Dachung,as he is called by friends and family,took Fuju to Xizang by air and rail.展开更多
文摘In order to systematically investigate the chemical constituents of Citri Reticulatae Folium (leaves of 'Fuju'), an analytical method that included high-performance liquid chromatography, diode array detection, electrospray ionization, and ion-trap time-of-flight mass spectrometry (HPLC-DAD-ESI-MSn) was used to separate and identify the individual chemical components of Citri Reticulatae Folium. As a result, 96 compounds were tentatively identified in this study: including 31 phenolic acids, 4 flavonoid aglycones, 6 flavonoid mono-O-glycosides, 10 flavonoid-O-diglycosides, 5 flavonoid mono-C-glycosides, 5 flavonoid di-C-glycosides, 6 flavonoid O,C-glycosides, 5 (3-hydroxy-3-methylglutaryl) glycosyl flavonoids, 1 flavan-3-ol, and 2 alkaloids. In addition, 21 polymethoxy flavonoids (PMFs) were identified in this paper. Among these compounds, 52 compounds, which were previously found in other Citrus plants, have been identified for the first time in Citri Reticulatae Folium. 15 compounds have not been previously found in the Citrus genus were identified. Moreover, 9 potentially new compounds have also been detected in this paper. This is the first report of the full characterization of chemical components of Citri Reticulatae Folium (leaves of'Fuju') by HPLC-DAD-ESI-MSn.
文摘When Dachung Wochen,a 35-year-old blind Tibetan,walks in the bustling streets of Lhasa,capital of the Xizang Autonomous Region,with his guide dog Fuju,people are amazed by their tacit cooperation.Fuju helps his master navigate every obstacle on the road.After spending only a year with him,he understands most of his commands in Tibetan.Dachung Wochen's journey with the four-year-old canine began in April 2024.After 28 days of professional training at the China Guide Dog Training Center in Dalian,Liaoning Province,Dachung,as he is called by friends and family,took Fuju to Xizang by air and rail.