As a unique art of language,humor is indispensable to human’s daily life,which reflects human's cognitive wisdom to⁃wards objective things and the society.The appreciation of humor mainly depends on the ability t...As a unique art of language,humor is indispensable to human’s daily life,which reflects human's cognitive wisdom to⁃wards objective things and the society.The appreciation of humor mainly depends on the ability to understand the unconventional use of language.Because humor plays an important role in daily life,psychologists,sociologists and linguists all try to explore its operation mechanism.HAPPY THEATER is a live comedy show by Zhejiang Satellite TV,inviting some movie and TV stars as vip actors,without lines or scripts.It is characterized by the ability to improvise in a high degree of performance and the use of humor in a flexible manner.The framework shifting theory is applied to analyze the humorous language of the program from the per⁃spective of cognitive linguistics in order to reveal the linguistic mechanism behind the humor.展开更多
Gitelman's syndrome(GS) is a salt-losing tubulopathy with an autosomal recessive inheritance caused by mutations of SLC12A3, which encodes for the thiazidesensitive Na Cl cotransporter. In this study we report a n...Gitelman's syndrome(GS) is a salt-losing tubulopathy with an autosomal recessive inheritance caused by mutations of SLC12A3, which encodes for the thiazidesensitive Na Cl cotransporter. In this study we report a new mutation of SLC12A3 found in two brothers affected by GS. Hypokalemia, hypocalciuria and hyperreninemia were present in both patients while hypomagnesemia was detected only in one. Both patients are compound heterozygotes carrying one well known GS associated mutation(c.2581 C > T) and a new one(c.283 del C) in SLC12A3 gene. The new mutation results in a possible frame-shift with a premature stopcodon(pG ln95 Argfs X19). The parents of the patients, heterozygous carriers of the mutations found in SLC12A3, have no disease associated phenotype. Therefore, the new mutation is causative of GS.展开更多
文摘As a unique art of language,humor is indispensable to human’s daily life,which reflects human's cognitive wisdom to⁃wards objective things and the society.The appreciation of humor mainly depends on the ability to understand the unconventional use of language.Because humor plays an important role in daily life,psychologists,sociologists and linguists all try to explore its operation mechanism.HAPPY THEATER is a live comedy show by Zhejiang Satellite TV,inviting some movie and TV stars as vip actors,without lines or scripts.It is characterized by the ability to improvise in a high degree of performance and the use of humor in a flexible manner.The framework shifting theory is applied to analyze the humorous language of the program from the per⁃spective of cognitive linguistics in order to reveal the linguistic mechanism behind the humor.
文摘Gitelman's syndrome(GS) is a salt-losing tubulopathy with an autosomal recessive inheritance caused by mutations of SLC12A3, which encodes for the thiazidesensitive Na Cl cotransporter. In this study we report a new mutation of SLC12A3 found in two brothers affected by GS. Hypokalemia, hypocalciuria and hyperreninemia were present in both patients while hypomagnesemia was detected only in one. Both patients are compound heterozygotes carrying one well known GS associated mutation(c.2581 C > T) and a new one(c.283 del C) in SLC12A3 gene. The new mutation results in a possible frame-shift with a premature stopcodon(pG ln95 Argfs X19). The parents of the patients, heterozygous carriers of the mutations found in SLC12A3, have no disease associated phenotype. Therefore, the new mutation is causative of GS.
