Fournier’s gangrene is a rare urological condition with a poor prognosis and an extremely high mortality rate.Infections caused by pathogenic microorganisms play a critical role in the pathogenesis of Fournier’s gan...Fournier’s gangrene is a rare urological condition with a poor prognosis and an extremely high mortality rate.Infections caused by pathogenic microorganisms play a critical role in the pathogenesis of Fournier’s gangrene.Rapid assessment and thorough debridement are crucial for survival and prognosis of patients with this disease.The present case involved a 62-year-old male patient with poorly controlled diabetes,who presented with unexplained scrotal swelling for 2 days at a local hospital where scrotal surgical debridement was performed.However,the procedure was unsuccessful.This case was characterized by rapid disease progression,widespread wound involvement,and dual infection with multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa.Our team performed early,extensive surgical debridement and,based on the results of antimicrobial susceptibility testing,initiated combination antibiotic therapy.The patient’s condition improved significantly after these interventions.However,the treatment was ultimately discontinued by the patient’s family for personal reasons,and follow-up care was declined.展开更多
基金supported by the Collaborative Innovation Center of China’s Ministry of Education(grant no.2020-39)Constructive Project of Innovative Talent Platform for Precise Repair of Wounds(grant no.2021-3)+1 种基金Scientific Research and Talent Training Fund of Kweichow Moutai Hospital(grant no.2022-13)Shanghai Wang Zhengguo Trauma Medicine Development Foundation(grant no.SZYZ-TR-05).
文摘Fournier’s gangrene is a rare urological condition with a poor prognosis and an extremely high mortality rate.Infections caused by pathogenic microorganisms play a critical role in the pathogenesis of Fournier’s gangrene.Rapid assessment and thorough debridement are crucial for survival and prognosis of patients with this disease.The present case involved a 62-year-old male patient with poorly controlled diabetes,who presented with unexplained scrotal swelling for 2 days at a local hospital where scrotal surgical debridement was performed.However,the procedure was unsuccessful.This case was characterized by rapid disease progression,widespread wound involvement,and dual infection with multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa.Our team performed early,extensive surgical debridement and,based on the results of antimicrobial susceptibility testing,initiated combination antibiotic therapy.The patient’s condition improved significantly after these interventions.However,the treatment was ultimately discontinued by the patient’s family for personal reasons,and follow-up care was declined.
