The theory of perfectly matched layer （PML） artificial boundary condition （ABC）, which is characterized by absorption any wave motions with arbitrary frequency and arbitrarily incident angle, is introduced. The co...The theory of perfectly matched layer （PML） artificial boundary condition （ABC）, which is characterized by absorption any wave motions with arbitrary frequency and arbitrarily incident angle, is introduced. The construction process of PML boundary based on elastodynamic partial differential equation （PDE） system is developed. Combining with velocity-stress hybrid finite element formulation, the applicability of PML boundary is investigated and the numerical reflection of PML boundary is estimated. The reflectivity of PML and multi-transmitting formula （MTF） boundary is then compared based on body wave and surface wave simulations. The results show that although PML boundary yields some reflection, its absorption performance is superior to MTF boundary in the numerical simulations of near-fault wave propagation, especially in comer and large angle grazing incidence situations. The PML boundary does not arise any unstable phenomenon and the stability of PML boundary is better than MTF boundary in hybrid finite element method. For a specified problem and analysis tolerance, the computational efficiency of PML boundary is only a little lower than MTF boundary.展开更多
In this paper, the general calculation formulas of radial matrix elements for relativistic n-dimensional hydrogen atom of spin S=0 are obtained, and the recurrence relation of different power order radial matrix eleme...In this paper, the general calculation formulas of radial matrix elements for relativistic n-dimensional hydrogen atom of spin S=0 are obtained, and the recurrence relation of different power order radial matrix elements are also derived.展开更多
Objective: To reveal the mechanism of Mahuang Lianqiao Chixiaodou decoction and its disassembled formula for improving the skin barrier function in a mouse model of atopic dermatitis(AD).Methods: Sixty specific-pathog...Objective: To reveal the mechanism of Mahuang Lianqiao Chixiaodou decoction and its disassembled formula for improving the skin barrier function in a mouse model of atopic dermatitis(AD).Methods: Sixty specific-pathogen free male BALB/c mice were randomly divided into the control group,model group, whole formula group(WF), exterior-releasing formula group(ERF), interior-clearing formula group(ICF), and positive control group(PC). A mouse model of AD was established using the semiantigen 2,4-dinitrofluorobenzene induction method. The lesion scores, transepidermal water loss and p H, and skin histopathology of mice in each group were observed. The expressions of filaggrin, loricrin,and involucrin were detected by the streptavidin peroxidase immunohistochemical method and western blotting, and their mRNA expressions were detected by quantitative polymerase chain reaction.Results: Mice in the WF, ERF, ICF, and PC groups showed reduced skin lesion performance, improved histopathology, decreased skin lesion score, transepidermal water loss and pH, and upregulated expressions of proteins including filaggrin, loricrin, and involucrin, and their mRNAs. The most obvious regulatory effect was observed in the WF group, followed by the ICF, ERF, and PC groups, accordingly.Conclusions: Mahuang Lianqiao Chixiaodou decoction and its disassembled formula can improve the skin barrier function in a mouse model of AD by upregulating filaggrin, loricrin, and involucrin, and their mRNA expressions, and the most optimal effect was noted in the WF group, followed by the ICF and ERF groups, which suggests that the effect of clearing heat and resolving dampness in improving the skin barrier function of AD is more obvious and is one of the key treatments for AD.展开更多
基金National Natural Science Foundation of China (50608024 and 50538050).
文摘The theory of perfectly matched layer （PML） artificial boundary condition （ABC）, which is characterized by absorption any wave motions with arbitrary frequency and arbitrarily incident angle, is introduced. The construction process of PML boundary based on elastodynamic partial differential equation （PDE） system is developed. Combining with velocity-stress hybrid finite element formulation, the applicability of PML boundary is investigated and the numerical reflection of PML boundary is estimated. The reflectivity of PML and multi-transmitting formula （MTF） boundary is then compared based on body wave and surface wave simulations. The results show that although PML boundary yields some reflection, its absorption performance is superior to MTF boundary in the numerical simulations of near-fault wave propagation, especially in comer and large angle grazing incidence situations. The PML boundary does not arise any unstable phenomenon and the stability of PML boundary is better than MTF boundary in hybrid finite element method. For a specified problem and analysis tolerance, the computational efficiency of PML boundary is only a little lower than MTF boundary.
文摘In this paper, the general calculation formulas of radial matrix elements for relativistic n-dimensional hydrogen atom of spin S=0 are obtained, and the recurrence relation of different power order radial matrix elements are also derived.
基金supported by the Natural Science Foundation of Beijing Municipality Surface Project(7192114)。
文摘Objective: To reveal the mechanism of Mahuang Lianqiao Chixiaodou decoction and its disassembled formula for improving the skin barrier function in a mouse model of atopic dermatitis(AD).Methods: Sixty specific-pathogen free male BALB/c mice were randomly divided into the control group,model group, whole formula group(WF), exterior-releasing formula group(ERF), interior-clearing formula group(ICF), and positive control group(PC). A mouse model of AD was established using the semiantigen 2,4-dinitrofluorobenzene induction method. The lesion scores, transepidermal water loss and p H, and skin histopathology of mice in each group were observed. The expressions of filaggrin, loricrin,and involucrin were detected by the streptavidin peroxidase immunohistochemical method and western blotting, and their mRNA expressions were detected by quantitative polymerase chain reaction.Results: Mice in the WF, ERF, ICF, and PC groups showed reduced skin lesion performance, improved histopathology, decreased skin lesion score, transepidermal water loss and pH, and upregulated expressions of proteins including filaggrin, loricrin, and involucrin, and their mRNAs. The most obvious regulatory effect was observed in the WF group, followed by the ICF, ERF, and PC groups, accordingly.Conclusions: Mahuang Lianqiao Chixiaodou decoction and its disassembled formula can improve the skin barrier function in a mouse model of AD by upregulating filaggrin, loricrin, and involucrin, and their mRNA expressions, and the most optimal effect was noted in the WF group, followed by the ICF and ERF groups, which suggests that the effect of clearing heat and resolving dampness in improving the skin barrier function of AD is more obvious and is one of the key treatments for AD.
