期刊文献+
共找到332篇文章
< 1 2 17 >
每页显示 20 50 100
Observation of the effect of one-to-one education on high-risk cases of diabetic foot 被引量:3
1
作者 Xia-Jun Fu Shi-Di Hu +3 位作者 Yin-Fang Peng Ling-Yan Zhou Ting Shu Dan-Dan Song 《World Journal of Clinical Cases》 SCIE 2021年第14期3265-3272,共8页
BACKGROUND Diabetes is a common chronic disease,and its global incidence is on the rise.The disease is directly attributed to insufficient insulin efficacy/secretion,and patients are often accompanied by multiple comp... BACKGROUND Diabetes is a common chronic disease,and its global incidence is on the rise.The disease is directly attributed to insufficient insulin efficacy/secretion,and patients are often accompanied by multiple complications.Diabetic foot is one of the most common complications of diabetes.Diabetic feet have ulcers and infections,which can eventually lead to amputation.Basic nursing care,such as lowering blood pressure and preventing foot skin infections in clinical nursing work,has positive significance for the prevention and control of diabetic feet.AIM To explore the positive significance of one-to-one education in high-risk cases of diabetic foot.METHODS This observation included 98 high-risk cases of diabetic foot in our hospital during the period from August 2017 to October 2019,and these patients were randomly divided into the basic nursing group and the one-to-one education group with 49 patients per group.The basic nursing group only received routine basic nursing,while the one-to-one education group gave patients one-to-one education on the basis of basic nursing.After nursing,the self-care ability and compliance behavior of the two groups were evaluated and compared between these two groups.The knowledge mastery of the patient and the satisfaction of nursing were accounted.RESULTS The assessment results of patients(self-care responsibility,self-care skills,selfconcept and self-care knowledge)were significantly higher in the one-to-one education group than in the basic nursing group.The scores of compliance behaviors(foot bathing,shoes and socks selection,sports health care)in the oneto-one education group were significantly higher than those in the basic nursing group.Patients in the one-to-one education group had a significantly higher level of knowledge mastery and satisfaction of nursing than the basic nursing group.CONCLUSION One-to-one education for high-risk cases of diabetic foot is helpful to improve the cognition and self-care ability of patients with diabetic foot,to ensure that patients follow the doctor’s advice of self-care and to improve their nursing satisfaction. 展开更多
关键词 High risk cases of diabetic foot One-to-one education Contrastive research Basic care Ability of self-care Compliance behavior
暂未订购
Synovial chondromatosis of the foot: Two case reports and literature review 被引量:1
2
作者 Luca Monestier Giacomo Riva +2 位作者 Placido Stissi Mahfuz Latiff Michele Francesco Surace 《World Journal of Orthopedics》 2019年第11期404-415,共12页
BACKGROUND Primary synovial chondromatosis(PSC) is a rare arthropathy of the synovial joints characterized by the formation of cartilaginous nodules, which may detach and become loose bodies within the joint and may u... BACKGROUND Primary synovial chondromatosis(PSC) is a rare arthropathy of the synovial joints characterized by the formation of cartilaginous nodules, which may detach and become loose bodies within the joint and may undergo secondary proliferation. PSC of the foot and ankle is exceedingly rare, with only a few cases reported in the literature. The diagnosis may be difficult and delayed until operative treatment, when it is confirmed by histological assessment. PSC may degenerate into chondrosarcoma. Operative treatment is the gold standard aiming to minimize pain, improve function, prevent or limit progression of arthritis. Surgical treatment consists in debridement by arthrotomic or arthroscopic management, but there is no consensus in the literature about timing of surgery and surgical technique. Thus, the aim of this study is to report the outcomes of the surgical treatment of two cases, together with a literature review.CASE SUMMARY We report two cases of patients affected by PSC of the foot in stage III, according to the Milgram classification: the former PSC localized in the ankle that underwent open surgery consisted of loose bodies removal;the latter in the subtalar joint, and the choice of treatment was the arthrotomy and debridement from loose bodies, in addition to the subtalar arthrodesis. Both patients returned to complete daily and working life after surgery.CONCLUSION Synovial chondromatosis is a rare benign pathology, even rarer in the ankle joint and especially in the foot. Surgery should be minimal in patients with ankle PSC,choosing the correct timing, waiting if possible until stage III. More aggressive and early surgery should be performed in patients with PSC of the foot,particularly the subtalar joint, due to the high risk of arthritic evolution. 展开更多
关键词 SYNOVIAL chondromatosis foot ANKLE REVIEW Treatment case REPORT
暂未订购
Cleft foot: A case report and review of literature 被引量:1
3
作者 Sergey S Leonchuk Andrey S Neretin Anthony J Blanchard 《World Journal of Orthopedics》 2020年第2期129-136,共8页
BACKGROUND Cleft foot is a very rare congenital anomaly,which is characterized by central rays deficiency of the foot.It is also known as split foot or ectrodactyly of the foot,and it is very often combined with split... BACKGROUND Cleft foot is a very rare congenital anomaly,which is characterized by central rays deficiency of the foot.It is also known as split foot or ectrodactyly of the foot,and it is very often combined with splitting of the hands.The defect develops due to insufficient activity of the median apical ectodermal ridge,which leads to an increase in cell death or a decrease in cell proliferation.Due to the rarity of the pathology,there are few papers on the surgical treatment of this congenital foot disease,and publications to date concern the treatment of children.CASE SUMMARY We present a clinical case of congenital splitting of the feet and hands in a 31-year-old woman and a long-term result of foot treatment using the minimal arrangement of the Ilizarov apparatus.The patient had paternal inheritance of the trait.After the surgical treatment,cosmetic view and functional condition of the foot were improved and persisted two years after intervention.There were no complications in the treatment process.CONCLUSION The possibility of dosed control and stable fixation of the foot rays made it possible to create favorable conditions for the healing of the central wound and the closure of the segment splitting without complications.The long-term outcome of the treatment of foot congenital splitting using the proposed Ilizarov apparatus arrangement has shown its effectiveness.Our approach should be considered as an option of treatment in similar cases. 展开更多
关键词 Cleft foot Split foot ECTRODACTYLY Congenital malformation ILIZAROV case report
暂未订购
Adolescent Lisfranc injury treated with TightRope^(TM):A case report and review of literature 被引量:2
4
作者 Themistoklis Tzatzairis Gregory Firth Lee Parker 《World Journal of Orthopedics》 2019年第2期115-122,共8页
BACKGROUND Lisfranc injuries are rare and can be easily missed. This injury is extremely rare in children, with limited published data. Different treatment options have been described; one of the options in adults is ... BACKGROUND Lisfranc injuries are rare and can be easily missed. This injury is extremely rare in children, with limited published data. Different treatment options have been described; one of the options in adults is the "mini" TightRope^(TM) Syndesmosis Device that provides non-rigid fixation with impressive results. However, there is no reference regarding the use of this device in children.CASE SUMMARY We describe the case of an 11-year-old girl who sustained a Lisfranc injury of her right foot that was initially missed in the Accident and Emergency department of her local hospital. This case was a ligamentous/periosteal sleeve avulsion type of Lisfranc injury and a percutaneous technique using the "mini" TightRope^(TM)syndesmosis device was used. Clinical and radiological results were excellent at final follow up.CONCLUSION The "mini" TightRope^(TM) syndesmosis device is a promising method of fixation for children with certain Lisfranc injuries. This method has many advantages,including the non-rigid type of the fixation and no need for subsequent metalwork removal. 展开更多
关键词 LISFRANC INJURY foot TIGHTROPE PAEDIATRIC case report
暂未订购
以双足疼痛发病的Morvan综合征一例
5
作者 陈嫄 赵胜男 +2 位作者 张淼 周玉颖 李攀 《中国现代神经疾病杂志》 北大核心 2025年第6期556-561,共6页
患者男性,71岁,受教育年限3年(小学肄业)。因双足疼痛7个月,行走困难渐进性加重3个月,言语混乱2月余,于2022年5月18日入院。患者入院前7个月(2021年10月)无明显诱因出现双足疼痛,呈持续刺痛感,程度剧烈,但可忍受,无头痛,无肢体无力;外... 患者男性,71岁,受教育年限3年(小学肄业)。因双足疼痛7个月,行走困难渐进性加重3个月,言语混乱2月余,于2022年5月18日入院。患者入院前7个月(2021年10月)无明显诱因出现双足疼痛,呈持续刺痛感,程度剧烈,但可忍受,无头痛,无肢体无力;外院头部MRI未见明显异常;腰椎MRI显示腰椎间盘膨出,髓内未见明显异常信号,诊断为“腰椎间盘膨出”,予布洛芬按需服用止痛,症状未见缓解。入院前4个月(2022年1月)无明显诱因出现发作性心前区不适、心悸,外院心电图及心肌酶谱未见明显异常,未予明确诊断,建议休息观察。入院前3月余(2022年2月)出现行走困难,活动时四肢震颤,因双足疼痛加剧,难以入睡,自行服用佐匹克隆(7.50 mg/d)等镇静催眠药,症状未见改善,因双足疼痛难忍,自行“洋铁皮”烫足,双足烫伤,外敷中药(具体成分和剂量不详)。 展开更多
关键词 肌纤维颤搐 肌强直 神经痛 低钠血症 病例报告
暂未订购
湖北省手足口病重症病例发生风险与年龄的定量分析 被引量:1
6
作者 刘天 黄淑琼 +4 位作者 阮德欣 向泉 秦周 谢聪 赵婧 《病毒学报》 北大核心 2025年第4期1018-1027,共10页
年龄的连续性变化对手足口病重症病例发生风险尚不清楚。本研究选取2009-2018年湖北省10岁及以下共104384例手足口病病例进行探讨。以是否为重症病例为因变量,控制性别、地区、病原学类型、发病至就诊时间、人群分类、发病年份及月份等... 年龄的连续性变化对手足口病重症病例发生风险尚不清楚。本研究选取2009-2018年湖北省10岁及以下共104384例手足口病病例进行探讨。以是否为重症病例为因变量,控制性别、地区、病原学类型、发病至就诊时间、人群分类、发病年份及月份等协变量,将年龄作为主要自变量,采用限制性立方样条(restricted cubic spline,RCS)函数进行分析,并开展不同性别和病原学类型的亚组分析。结果显示,重症病例1150例,重症率为1.10%。RCS模型提示年龄是重症发生的重要影响因素(χ^(2)=1426.32,P<0.001),且与重症发生风险之间存在非线性关系(χ^(2)=3.43,P=0.064)。重症发生风险总体随年龄增长而下降(AAPC=-13.71%,95%CI:-13.79%~-13.64%),分段对数线性回归拟合发现拐点年龄为2.66岁(95%CI:2.61~2.70岁),其中2.66岁前后重症手足口病发生风险APC依次为-23.69%(95%CI:-24.02%~-23.35%)、-8.51%(95%CI:-8.59%~-8.42%)。亚组分析显示,男性(χ^(2)=4.31,P=0.038)和EV-A71型(χ^(2)=3.59,P=0.058)病例中,年龄对重症风险同样存在非线性效应,趋势与总体一致;而CVA16型(OR=0.93,95%CI:0.68~1.24)、其他肠道病毒(OR=0.95,95%CI:0.77~1.15)年龄对重症风险无显著影响。研究表明,年龄与手足口病重症风险之间存在总体下降的非线性剂量-反应关系,关键拐点为2.66岁,提示应重点关注低龄儿童,特别是2.66岁以下的EV-A71型感染患儿的病情进展。 展开更多
关键词 手足口病 重症 年龄 限制立方样条函数
原文传递
Investigation on Factors Associated with Severe Hand, Foot and Mouth Disease 被引量:1
7
作者 Gui-lin Yang Ying-xia Liu +5 位作者 Mu-tong Fang Yan-xia He John Nunnari Jing-jing Xie Xiao-hua Le Bo-ping Zhou 《国际感染病学(电子版)》 CAS 2014年第2期82-91,共10页
Objective To analyze the clinical and laboratory features of patients with mild and severe HFMD to identify early predictive or diagnostic markers for severe cases. Methods Samples of feces, nasopharyngeal-swab specim... Objective To analyze the clinical and laboratory features of patients with mild and severe HFMD to identify early predictive or diagnostic markers for severe cases. Methods Samples of feces, nasopharyngeal-swab specimens, peripheral blood, serum and cerebral spinal fluid were collected. Postmortem pathological examination was conducted on 2 dead patients with complication due to neurogenic pulmonary edema. Reverse transcription-polymerase chain-reaction(RT-PCR), culture and isolation of enterovirus 71(EV71) were performed to detect EV71 infection. Both univariate and multivariate logistic analysis were used to identify factors associated with severe cases. Results EV71 was mainly responsible for HFMD. In this study, 5 isolated EV71 strains belonged to C4 gene subtype. Compared with mild patients, EV71-RNA detection rate was higher and Cox A16 detection rate was lower among severe patients(P < 0.01). Inflammatory cell infiltration in the lung, cardiac and liver tissues were mild by postmortem pathological examination. It was found that body temperature, vomitting, limb tremor, neutrophil, blood glucose and EV71 infection were significantly related to the severe cases by univariate logistic analysis. However, after multivariate logistic regression analysis, only vomiting(OR 16.1, CI 2.3-110.5, P < 0.01) and limb tremor(OR 117.6, CI 13.8-1004.5, P < 0.01) were significantly and independently correlated with the severe cases.Conclusions EV71 was mainly responsible for HFMD, particularly for severe cases. Vomiting and limb tremor were predictive markers for severe cases. 展开更多
关键词 Hand foot and mouth disease Enterovirus 71 Predictive marker Severe cases
暂未订购
福州市手足口病重症患儿危险因素分析
8
作者 郑霄雁 郑成浩 +2 位作者 林风华 黄意坚 郑本汇源 《解放军医学杂志》 北大核心 2025年第9期1110-1116,共7页
目的 探究福州市手足口病重症患儿的危险因素,为疾病防控提供科学依据。方法 检索中国疾病预防控制信息系统,收集2017-2024年发病的福州市手足口病重症患儿信息,并按重症患儿的同发病时期、同发病地区、父母教育学历、年龄±1岁进... 目的 探究福州市手足口病重症患儿的危险因素,为疾病防控提供科学依据。方法 检索中国疾病预防控制信息系统,收集2017-2024年发病的福州市手足口病重症患儿信息,并按重症患儿的同发病时期、同发病地区、父母教育学历、年龄±1岁进行频数匹配,形成非重症组。收集两组人口学特征、临床表现、既往病史及病原学感染型别等信息;采用logistic回归模型分析重症患儿的危险因素。结果 2017-2024年福州市共报告手足口病重症患儿503例,匹配非重症病例1053例。重症组散居儿童、归属地为农村、发病与就诊间隔时间>2 d占比高于非重症组,而EV71疫苗接种、有饭前便后洗手习惯、照料者有手足口病防病教育经历占比则低于非重症组,差异均有统计学意义(P<0.001);重症组发热>3 d、神志改变/惊厥、手足抖动/抽搐、有感染性疾病史和EV71阳性的占比明显高于非重症组(P<0.001)。多因素logistic回归分析显示,散居儿童(OR=3.213,95%CI 1.913~5.398)、现住址归属农村(OR=2.121,95%CI 1.513~2.973)、未接种EV71疫苗(OR=3.141,95%CI 1.996~4.945)、发病与就诊间隔时间>2 d(OR=2.004,95%CI 1.410~2.849)、患儿饭前便后无洗手习惯(OR=3.927,95%CI 1.718~5.356)、照料者未接受手足口病防病知识教育(OR=2.465,95%CI 1.807~3.362)、发热>3 d(OR=2.585,95%CI 1.801~3.709)、神志改变/惊厥(OR=4.059,95%CI 2.731~6.031)、手足抖动/抽搐(OR=2.087,95%CI 1.398~3.117)、有感染性疾病史(OR=3.369,95%CI 1.725~6.335)、EV71阳性(OR=3.854,95%CI 2.678~5.545)是手足口病重症患儿的危险因素(P<0.001)。重症组的治愈时间长于非重症组[18(5,32) d vs. 11(4,23)d,P<0.001]。结论 应针对手足口病重症患儿的危险因素,做好重点人群防控,加强健康宣教和推进EV71疫苗接种,提升重症病例救治水平,以降低发生重症的风险。 展开更多
关键词 手足口病 重症病例 危险因素 LOGISTIC回归 免疫接种
暂未订购
合并平足与拇外翻的先天性足底肌肥大1例
9
作者 秦玉岩 王正义 +5 位作者 潘旭月 马占华 吴俊德 洪茂 常青 陈兆军 《中国骨伤》 2025年第5期540-543,共4页
患者,女,16岁,主因“左足底膨隆16年,伴行走后疼痛3年”于2023年12月13日入院。患者诉自出生后发现左足底膨隆,随发育缓慢增大,无疼痛麻木等不适。2020年无明显诱因出现行走后左足底疼痛,休息后可缓解。2021年就诊于外院诊断为平足症,... 患者,女,16岁,主因“左足底膨隆16年,伴行走后疼痛3年”于2023年12月13日入院。患者诉自出生后发现左足底膨隆,随发育缓慢增大,无疼痛麻木等不适。2020年无明显诱因出现行走后左足底疼痛,休息后可缓解。2021年就诊于外院诊断为平足症,行足弓垫治疗1年未见缓解。2023年1月就诊于我院门诊,行足部负重X线检查示左足平足,超声检查显示左足底多个肌肉发育异常,左足拇展肌、趾短屈肌. 展开更多
关键词 足底肌肉肥大 扁平足 平足症 拇外翻 病例报告
在线阅读 下载PDF
难治性糖尿病足1例的综合救治
10
作者 刘佳为 王敏 +1 位作者 张瑞 童强 《现代医药卫生》 2025年第9期2076-2080,共5页
该院收治1例64岁男性难治性糖尿病足患者,因左足破溃30^(+) d,左足红肿、第1足趾及足背皮肤变黑伴发热3 d入院,合并重度感染、下肢动脉狭窄和骨髓炎。经包括截除坏死足趾、下肢动脉球囊扩张,以及支架植入、扩大清创、皮瓣移植等在内的... 该院收治1例64岁男性难治性糖尿病足患者,因左足破溃30^(+) d,左足红肿、第1足趾及足背皮肤变黑伴发热3 d入院,合并重度感染、下肢动脉狭窄和骨髓炎。经包括截除坏死足趾、下肢动脉球囊扩张,以及支架植入、扩大清创、皮瓣移植等在内的多学科协作治疗后创面愈合出院,出院3个月后恢复良好。表明多学科综合治疗可有效降低难治性糖尿病足患者截肢率。 展开更多
关键词 难治性糖尿病足 综合救治 血运重建 创面修复 病例报告
暂未订购
DIY人工胰腺在1例糖尿病足中的应用
11
作者 杜蓥漩 王渊 +2 位作者 石莹 何林翰 王慧 《现代医药卫生》 2025年第9期2081-2083,共3页
该院收治1例55岁男性患者,因血糖控制欠佳、右足破溃3 d入院,糖尿病病程23年,诊断为糖尿病足伴感染。在使用胰岛素泵联合指尖末梢血糖监测控制血糖欠佳的情况下转为DIY人工胰腺(DIY-APS)联合控制,葡萄糖在目标范围内时间达94.59%,血糖... 该院收治1例55岁男性患者,因血糖控制欠佳、右足破溃3 d入院,糖尿病病程23年,诊断为糖尿病足伴感染。在使用胰岛素泵联合指尖末梢血糖监测控制血糖欠佳的情况下转为DIY人工胰腺(DIY-APS)联合控制,葡萄糖在目标范围内时间达94.59%,血糖波动明显减少,创面愈合良好。高低血糖波动是糖尿病足进展的关键,但传统监测血糖方法难以全面实时反应患者血糖波动,以及根据血糖情况作出及时处理,DIY-APS通过实时闭环输注实现精准安全控糖,为糖尿病足综合管理提供了新策略。 展开更多
关键词 糖尿病足 DIY人工胰腺 血糖控制 病例报告
暂未订购
常州市手足口病相关危险因素流行病学调查 被引量:33
12
作者 姚杏娟 郝超 +3 位作者 徐辉 陈聪 张惠力 邓一玫 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2010年第9期1275-1278,共4页
目的:探讨常州市人群发生手足口病(hand-foot-mouth disease,HFMD)的危险因素。方法:采用病例-对照研究方法,在常州市选择经临床明确诊断的108例手足口病患者和按年龄、性别频数匹配的108名对照,采用单因素分析和多因素Logistic回归分析... 目的:探讨常州市人群发生手足口病(hand-foot-mouth disease,HFMD)的危险因素。方法:采用病例-对照研究方法,在常州市选择经临床明确诊断的108例手足口病患者和按年龄、性别频数匹配的108名对照,采用单因素分析和多因素Logistic回归分析,分析HFMD的主要危险因素。结果:单因素分析发现5个暴露因素与HFMD发生有关;多因素分析显示HFMD有2个主要危险因素和1个保护因素,分别是居住在农村(0R=2.191,95%CI:1.174~4.088)、有饮用生水习惯(0R=2.441,95%CI:1.050~5.675)、幼儿饭前便后洗手(OR=0.505,95%CI:0.259~0.983)。结论:幼儿良好的环境卫生、家长及个人良好的卫生习惯是预防手足口病的重要因素,为今后健康宣传教育提供了重要的理论支持。 展开更多
关键词 手足口病 病例一对照研究 危险因素
原文传递
手足口病重症病例的流行特征及危险因素 被引量:36
13
作者 刘丹 苏豪浩 +3 位作者 王建红 吴国兰 项东 张绍文 《实用医学杂志》 CAS 北大核心 2013年第6期995-998,共4页
目的:分析手足口病重症病例的流行特征及相关危险因素。方法:对用Real-timeRT-PCR方法确诊的780例手足口病患儿,对比重症病例和普通病例,分析重症病例的流行特征及危险因素。结果:780例患儿中,重症和普通病例两组平均年龄分别为(1.6... 目的:分析手足口病重症病例的流行特征及相关危险因素。方法:对用Real-timeRT-PCR方法确诊的780例手足口病患儿,对比重症病例和普通病例,分析重症病例的流行特征及危险因素。结果:780例患儿中,重症和普通病例两组平均年龄分别为(1.6±0.9)岁和(3.0±1.9)岁(P﹤0.001);重症病例多发于1~2岁(51.8%)、夏季(61.4%)和唐山北部地区(58.5%);EV71感染并发重症手足口病的相对危险度(RR)高于普通病例(P<0.001)。结论:手足口病为唐山地区常见的儿童疾病,年龄1~2岁、感染EV71是引起手足口病重症病例的主要危险因素。 展开更多
关键词 手足口病 重症病例 危险因素
暂未订购
北京市2010年手足口病死亡病例流行病学及临床特征分析 被引量:13
14
作者 刘白薇 王全意 +3 位作者 李锡太 贾蕾 张奕 黎新宇 《现代生物医学进展》 CAS 2011年第22期4264-4266,共3页
目的:通过描述2010年北京市手足口病死亡病例的流行病学特点和临床特点,分析手足口病重症病例发生死亡的危险因素,为防制手足口病,减少手足口病的死亡提供科学依据。方法:采用现况描述及病例对照研究的方法,对2010年北京市手足口病死亡... 目的:通过描述2010年北京市手足口病死亡病例的流行病学特点和临床特点,分析手足口病重症病例发生死亡的危险因素,为防制手足口病,减少手足口病的死亡提供科学依据。方法:采用现况描述及病例对照研究的方法,对2010年北京市手足口病死亡病例的特点进行分析。结果:2010年北京市共报告18例手足口病死亡病例,88.9%分布在5-8月份;死亡病例的男女比例为3.5:1;年龄均小于4岁;流动人口聚集区的死亡病例较多;散居儿童及外地户籍儿童比例高,分别为83.3%和94.4%。死亡病例均出现出疹、发热及神经精神系统症状,整体精神状况,呼吸功能指标以及循环系统受累明显。与重症痊愈病例相比,感染EV71型病毒是发生死亡的危险因素(x2=4.774,P=0.029)。结论:手足口病死亡病例分布与重症病例分布基本一致。应对流动人口聚集地区的4岁以下婴幼儿重症病例进行重点防控。 展开更多
关键词 手足口病 死亡病例 流行病学 临床特征
原文传递
上海市杨浦区2012年手足口病聚集性疫情流行特征分析 被引量:9
15
作者 乔鹏 张家琪 +1 位作者 王琳 谢梦 《中国预防医学杂志》 CAS 2013年第12期927-929,共3页
目的分析上海市杨浦区2012年手足口病聚集性疫情流行特征,为制定手足口病防控措施提供科学依据。方法应用描述性流行病学方法,对杨浦区2012年手足口病聚集性疫情进行分析,计数资料用χ2检验,计量资料用方差分析,P〈0.05为差异有统计学... 目的分析上海市杨浦区2012年手足口病聚集性疫情流行特征,为制定手足口病防控措施提供科学依据。方法应用描述性流行病学方法,对杨浦区2012年手足口病聚集性疫情进行分析,计数资料用χ2检验,计量资料用方差分析,P〈0.05为差异有统计学意义。结果 2012年杨浦区共报告手足口病聚集性疫情80起,波及18 384人,涉及病例337例,平均患病率1.83%,无重症、死亡病例。发生在中小学3起,占3.75%,为不同的3家学校,发生率为2.94%;发生在托幼机构77起,占96.25%,涉及托幼机构56家,发生率为52.83%。报告高峰在4~6月份。疫情的持续时间与疫情非及时处理(首发病例发病时间-停课时间间隔)(r=0.352,P=0.002)及发病人数(r=0.458,P〈0.001)之间呈显著正相关,在控制发病人数影响后,疫情持续时间与疫情非及时处理的统计学相关性增强(r=0.385,P=0.001)。在因素不变的情况下,聚集性疫情每延迟处理2d,或发病人数每增加1人,疫情时间均会延长1d,即:y=0.09+0.81x1+0.51x2。采样的34起疫情中,由EV71、Cox A16、其他肠道病毒引起的疫情数分别为10(29.41%)、6(17.65%)和9起(26.47%)。结论防控的重点仍是托幼机构,加强全年监测,深入研究病原变异,督促学校做好晨检和及时上报工作,规范处置能很好的控制疫情的发展。 展开更多
关键词 手足口病 聚集性疫情 托幼机构 流行病学
原文传递
重症手足口病主要危险因素的Meta分析 被引量:9
16
作者 冯慧芬 赵秋民 +1 位作者 段广才 朱光 《吉林大学学报(医学版)》 CAS CSCD 北大核心 2015年第5期974-979,共6页
目的:探讨重症手足口病(HFMD)的主要危险因素,为其早期识别、及时治疗提供参考依据。方法:应用Meta分析对1990-2014年国内外关于重症HFMD患者危险因素的病例-对照研究进行综合分析,经异质性检验,分别采用固定效应模型和随机效应模... 目的:探讨重症手足口病(HFMD)的主要危险因素,为其早期识别、及时治疗提供参考依据。方法:应用Meta分析对1990-2014年国内外关于重症HFMD患者危险因素的病例-对照研究进行综合分析,经异质性检验,分别采用固定效应模型和随机效应模型进行相对危险度(OR)值合并,计算其95%可信区间(95%CI),并进行敏感性分析及发表偏倚评估。结果:共纳入文献19篇,病例(重症HFMD患者)2 868例,对照(轻症HFMD患者)6 676例。异质性检验,重症HFMD危险因素对应文献异质性检验I2值分别为,年龄≤3岁70%、居住地为农村0%、发病至入院时间≥3d23%、肠道病毒71型(EV71)感染75%、发热≥38.5℃0%、持续发热时间≥3d14%、精神萎靡0%、高血糖(≥6.11mmol·L^-1)51%,各危险因素合并OR及其95%CI分别为2.90(2.14-3.94)、2.21(1.66-2.93)、2.02(1.46-2.79)、2.90(1.24-6.81)、3.13(1.99-4.94)、5.48(3.56-8.45)、4.25(2.45-7.37)和2.87(1.49-5.52)。敏感性分析,固定效应模型和随机效应模型计算结果一致。发表偏倚评估,无明显发表偏倚。结论:农村低龄婴幼儿、就医延迟、EV71感染、持续高热、精神萎靡和血糖水平升高可能是重症HFMD患者发病的主要危险因素。 展开更多
关键词 重症手足口病 病例-对照研究 META分析 危险因素
暂未订购
上一页 1 2 17 下一页 到第
使用帮助 返回顶部