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Simultaneous determination of 20 food additives by high performance liquid chromatography with photo-diode array detector 被引量:8
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作者 Kang Ma Ya Nan Yang +2 位作者 Xiao Xiong Jiang Min Zhao Ye Qiang Cai 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第4期492-495,共4页
An efficient and accurate analytical method was developed for the simultaneous determination of 20 synthetic food additives, including three sweeteners,seven food colorants,nine synthetic preservatives and caffeine,by... An efficient and accurate analytical method was developed for the simultaneous determination of 20 synthetic food additives, including three sweeteners,seven food colorants,nine synthetic preservatives and caffeine,by high performance liquid chromatography (HPLC) with photodiode array detector(PDA).This method permits the detection of food additives at very low concentrations(0.005-0.150μg/mL).The applicability was verified by the determination of food additives present in various foodstuffs. 展开更多
关键词 food additives Liquid chromatography Photodiode array detector DRINKS
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Risk Analysis of Sulfites Used as Food Additives in China 被引量:9
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作者 ZHANG Jian Bo ZHANG Hong +4 位作者 WANG Hua Li ZHANG Ji Yue LUO Peng Jie ZHU Lei WANG Zhu Tian 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2014年第2期147-154,共8页
This study was to analyze the risk of sulfites in food consumed by the Chinese people and assess the health protection capability of maximum-permitted level (MPL) of sulfites in GB 2760-2011. Sulfites as food additi... This study was to analyze the risk of sulfites in food consumed by the Chinese people and assess the health protection capability of maximum-permitted level (MPL) of sulfites in GB 2760-2011. Sulfites as food additives are overused or abused in many food categories. When the MPL in GB 2760-2011 was used as sulfites content in food, the intake of sulfites in most surveyed populations was lower than the acceptable daily intake (ADI). Excess intake of sulfites was found in all the surveyed groups when a high percentile of sulfites in food was intaken. Moreover, children aged 1-6 years are at a high risk to intake excess sulfites. The primary cause for the excess intake of sulfites in Chinese people is the overuse and abuse of sulfites by the food industry. The current MPL of sulfites in GB 2760-2011 protects the health of most populations. 展开更多
关键词 Risk Analysis of Sulfites Used as food additives in China
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Network Management of Food Additives Quality Analysis and Inspection 被引量:3
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作者 Hairui Zhang Guofu Zhang Li Zhang 《Journal of Chemistry and Chemical Engineering》 2015年第7期468-471,共4页
In this paper, on the basis of the implementation of the national chemical industry standard analytical test methods and analysis of test items, a food additive quality analysis and inspection of network management ap... In this paper, on the basis of the implementation of the national chemical industry standard analytical test methods and analysis of test items, a food additive quality analysis and inspection of network management applications are developed using the development technology of Visual Basic language and computer system operating environment, to achieve a network management software for users on food additives of quality analytical testing. The software sets up an information sharing network platform for enterprise and quality management departments, which is a major innovation in the food additive quality analysis on test management methods and tools. 展开更多
关键词 food additives quality analysis Visual Basic language network management software development.
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Effects of Food Additives on Rehydration Properties of Frozen Dumpling Wrappers 被引量:1
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作者 Hua LI Xingli JIAO +4 位作者 Xiang GUI Ying XIONG Junling LI Weihua WANG Feng CAO 《Agricultural Biotechnology》 CAS 2014年第6期61-66,共6页
With the vacuum freeze-drying technology, frozen dumpling wrappers were prepared, to investigate the effects of six kinds of food additives, including modified starch, compound phosphate, maltodextrin, guar gum, disti... With the vacuum freeze-drying technology, frozen dumpling wrappers were prepared, to investigate the effects of six kinds of food additives, including modified starch, compound phosphate, maltodextrin, guar gum, distilled monoglycerides and transglutaminase (TG enzyme), on the drying rate, rehydration ratio and sense value of the frozen dumpling wrappers. The results showed that, with respective addition of 6% modified starch, O. 1% compound phosphate, 10% maltodextrin, 0.4% guar gum, 0.4% distilled monoglyceride and 0.3% transglutaminase, the drying rate, rehydration ratio and sense value of the frozen dumpling wrappers were the highest. 展开更多
关键词 Vacuum freeze-drying Dumpling wrappers food additives Drying rate Rehydration ratio Sense value
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Research on Detection of Food additives Based on Terahertz Spectroscopy and Analytic Hierarchy Process 被引量:1
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作者 Miaoyu Zhao Fang Yan +1 位作者 Wenwen Li Yangshuo Liu 《Instrumentation》 2024年第1期30-37,共8页
Terahertz time-domain spectroscopy is a kind of far-infrared spectroscopy technology,and its spectrum reflects the internal properties of substances with rich physical and chemical information,so the use of terahertz ... Terahertz time-domain spectroscopy is a kind of far-infrared spectroscopy technology,and its spectrum reflects the internal properties of substances with rich physical and chemical information,so the use of terahertz waves can be used to qualitatively identify food additives containing nitrogen elements.Analytic hierarchy process(AHP)was originally used to solve evaluation-type problems,and this paper introduces it into the field of terahertz spectral qualitative analysis,proposes a terahertz time-domain spectral qualitative identification method combined with analytic hierarchy process,and verifies the feasibility of the method by taking four common food additives(xylitol,L-alanine,sorbic acid,and benzoic acid)and two illegal additives(melamine,and Sudan Red No.I)as the objects of study.Firstly,the collected terahertz time-domain spectral data were pre-processed and transformed into a data set consisting of peaks,peak positions,peak numbers and overall trends;then,the data were divided into comparison and test sets,and a qualitative additive identification model incorporating analytic hierarchy process was constructed and parameter optimisation was performed.The results showed that the qualitative identification accuracies of additives based on single factors,i.e.,overall trend,peak value,peak position,and peak number,were 80.23%,70.93%,67.44%,and 40.70%,respectively,whereas the identification accuracy of the analytic hierarchy process qualitative identification method based on multi-factors could be improved to 92.44%.In addition,the fuzzy characterisation of the absorption spectrum data was binarised in the data pre-processing stage and used as the base data for the overall trend,and the recognition accuracy was improved to 94.19%by combining the fuzzy characterisation method of such data with the hierarchical analysis qualitative recognition model.The results show that it is feasible to use terahertz technology to identify different varieties of additives,and this paper constructs a hierarchical analytical qualitative model with better effect,which provides a new means for food additives detection,and the method is simple in steps,with a small demand for samples,which is suitable for the rapid detection of small samples. 展开更多
关键词 terahertz time-domain spectroscopy analytic hierarchy process qualitative identification food additives
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Consumers’ Perception and Knowledge of Food Additives in Senegal: A Pilot Study
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作者 Alé Kane Hamidou Mbodji +4 位作者 Papa Mamadou Dit Doudou Sylla Alioune Sow Abdoulaye Tamba Malick Mbengue Mady Cissé 《Open Journal of Applied Sciences》 2024年第1期38-50,共13页
Food safety has become a major concern for consumers, as well as a priority for regulatory authorities. Faced with the growing industrial and domestic use of food additives, many questions are being asked and concerns... Food safety has become a major concern for consumers, as well as a priority for regulatory authorities. Faced with the growing industrial and domestic use of food additives, many questions are being asked and concerns are being felt by consumers around the world. Consumer perception defines the acceptability or rejection of food products, and has an impact on consumption patterns and behavior. To assess the level of knowledge and perception of food additives, a pilot study was carried out on a sample of 200 people in Dakar and Saint-Louis. A questionnaire was used to assess the acceptance or rejection, use and impact of food additives by consumers in Senegal. The results revealed several aspects. On the whole, the people surveyed expressed great mistrust and even rejection of these substances added to food products. This consumer perception is shared throughout the world, as indicated in numerous surveys. It also emerges from this study that, although most consumers are aware of the existence of these additives and their uses in the home, they feel that the use of these substances in industrial production is too excessive. What’s more, consumers associate food additives with numerous pathologies such as cancer, diabetes, hypertension, stroke and even sexual impotence. For some of these indexed pathologies, scientific studies have reached the same conclusions, although controversy still persists. On the other hand, for some of the other adverse effects mentioned, no cause-and-effect relationship has been scientifically demonstrated. In these latter cases, it seems that negative communication, misinformation and misconceptions have a major influence on consumer perception of food additives. 展开更多
关键词 Consumer Survey food additives KNOWLEDGE PERCEPTION Senegal
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Food Additives-Ascorbic Acid Quality Assay Test Intelligent Management 被引量:1
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作者 Hairui Zhang Li Zhang +1 位作者 Helin Ye Guofu Zhang 《Journal of Chemistry and Chemical Engineering》 2018年第1期20-25,共6页
In this paper, based on the analysis and test methods of national standards (GB 14754-2010) and chemical analysis and test items carried out by chemical enterprises, a set of automatic processing of quality analysis... In this paper, based on the analysis and test methods of national standards (GB 14754-2010) and chemical analysis and test items carried out by chemical enterprises, a set of automatic processing of quality analysis test data of ascorbic acid products was developed by using access database technology and Visual Basic programming language system, and its stability was investigated. The results show that the software can manage intelligently all aspects of the quality analysis and test of ascorbic acid products, uploading timely the data and results of the analysis and inspection to the network and saving it for users, enterprises and quality management, which set up a network of information sharing platform to ensure the authenticity and reliability of measurement results, improving greatly the speed of data processing, saving valuable time, reducing production costs with good economic efficiency and social benefit. It has practical value for ascorbic acid quality analysis test data processing automatically the results of the implementation of intelligent management. 展开更多
关键词 food additive ascorbic acid quality analysis test intelligent management software development.
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Validation of a HPLC Method for Determination of Glutamine in Food Additives Using Post-Column Derivatization 被引量:1
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作者 Marlus Chorilli Herida Regina Nunes Salgado +1 位作者 Fabiana De Santana Santos Lucelia Magalhaes Da Silva 《American Journal of Analytical Chemistry》 2012年第2期113-117,共5页
An ion-exchange chromatography (IEC) followed by post-column derivatization method was validated for the determination of glutamine in food additive products. The chromatographic method was carried out on a sodium cat... An ion-exchange chromatography (IEC) followed by post-column derivatization method was validated for the determination of glutamine in food additive products. The chromatographic method was carried out on a sodium cation-exchange column and using detection at 570 nm. The mobile phase consisted of sodium eluant, pH 3.15, with 5% sulfolane, sodium eluant, pH 7.40 and sodium column regenerant. The method was linear in the range of 4 - 50 μg/mL (r2 = 0.9999). The accuracy was 99.78%. Moreover, method validation demonstrated acceptable results for precision and robustness. The method was found to be able to use for routine analysis of the glutamine. 展开更多
关键词 GLUTAMINE food Additive Product Liquid Chromatography
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In vitro assessments of antioxidant,antimicrobial,cytotoxicity and anti-inflammatory characteristics of flavonoid fractions from flavedo and albedo orange peel as novel food additives
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作者 Dina Mostafa Mohammed Sodaf A.Maan +1 位作者 Doha H.Abou Baker Safaa S.Abozed 《Food Bioscience》 2024年第6期6727-6738,共12页
Natural food additives have gained popularity in recent years among consumers and the food service sector.Flavonoids are beneficial to people’s health and can be found in many different types of fruits and vegetables... Natural food additives have gained popularity in recent years among consumers and the food service sector.Flavonoids are beneficial to people’s health and can be found in many different types of fruits and vegetables.So,this work’s purpose is to isolate and identify the flavonoid fractions isolated from the flavedo and albedo orange peel and examine their biological properties as potential novel food additives.Total phenolic and total flavonoid contents of water,ethanolic,and ethyl acetate extracts were determined.The isolated flavonoid fractions were identified,quantified,and classified using HPLC following isolation using column chromatography.Evaluations were conducted on the antimicrobial,anticancer,and anti-inflammatory characteristics of flavonoid fractions.The findings indicated that,compared to the albedo layer,the flavedo layer had higher total phenolic and total flavonoid concentrations.That ethyl acetate solvent was the most suitable for extracting flavonoids from orange peels.According to the HPLC analysis,the isolated flavonoid fractions contain a variety of flavonoid subclasses,including flavones,flavanones,and flavonols.The extracted flavonoid fractions showed efficacy against all tested strains of pathogens,exerted the largest cytotoxic effect,and displayed the highest anti-inflammatory capabilities.In conclusion,the flavedo and albedo orange peels have significant nutritional value that humans can consume,along with the potential for their use as novel natural food additives. 展开更多
关键词 Orange peel Antibacterial and antifungal Anti-inflammatory activities Flavonoid fractions food additives food industry
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Rapid and accurate detection and identification of food additives in liquid environments via enrichment surface-enhanced Raman spectroscopy method and sparse feature-based model
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作者 Lili Kong Xinna Yu +3 位作者 Qifang Sun Jie Chen Meizhen Huang Tianyuan Liu 《Food Bioscience》 2025年第6期5273-5281,共9页
Rapid and accurate detection and identification of food additives is crucial to ensuring food safety.However,trace-level additives,complex matrices,and similar molecular structures often hinder sensitive detection and... Rapid and accurate detection and identification of food additives is crucial to ensuring food safety.However,trace-level additives,complex matrices,and similar molecular structures often hinder sensitive detection and accurate identification.Herein,we propose a novel strategy combining enrichment surface-enhanced Raman spectroscopy(SERS)method with sparse feature-based models,which enables the effective sensitive detection and precise identification of food additives.The strategy synthesizes a graphene oxide/Au@Ag nanobones(GO/Au@Ag NBs)membrane for simultaneous enrichment and detection target analytes.The integrated utilization of localized surface plasmon resonance characteristics of Au@Ag NBs,adsorption function of graphene oxide,and stability of microporous membrane provide satisfactory performance of the SERS membrane.Combined with a portable filtration unit could effectively enrich and rapidly detect food additives in liquid environment.Subsequently,extracting and optimizing the spectral sparse features by designing suitable transform bases and sensing matrices utilizing the theory of compressed sensing.The original spectra could be reconstructed with high quality through optimized sparse features,which indicates that the sparse features retain comprehensive key information while reducing the data dimensions.The sparse feature-based identification models are trained to achieve exceptional accuracy in food additives recognition,consistently surpassing 0.94,which outperforms conventional modeling algorithms based principal component analysis or t-distributed stochastic neighbor embedding.The efficacy of this method is demonstrated using six trace-level food additives in two categories with similar spectral performance.This development of enrichment SERS method and sparse feature-based model establishes a rapid and reliable method for the detection and identification of food additives in liquid environments. 展开更多
关键词 Surface-enhanced Raman spectroscopy(SERS) Enrichment Sparse feature food additives identification Similar molecular structure
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A stochastic predator-prey model with additional food for predator incorporating fear effect and a prey refuge
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作者 XUE Ren-xiu SHAO Yuan-fu CUI Min-juan 《Applied Mathematics(A Journal of Chinese Universities)》 2026年第1期78-98,共21页
In this paper,we study a predator-prey model with additional food for predator.By using white noise to perturb the natural growth rates and introduce a jump process,we model the corresponding stochastic differential e... In this paper,we study a predator-prey model with additional food for predator.By using white noise to perturb the natural growth rates and introduce a jump process,we model the corresponding stochastic differential equations.The effect of fear and prey refuge on population dynamics is also considered.First,we use Itô's formula to prove the existence and uniqueness of a global positive solution and its boundedness.Next,sufficient conditions for the extinction and persistence of both species have been given.Then the stochastic permanence of our system is investigated under some conditions.Our main results demonstrate that sufficiently large white noise could drive both species to extinction.However,Lévy noise enhances the survival of both prey and predator species.Our analytical derivations are justified through numerical simulations which show the reliability of the model from the ecological point of view.In addition,we have investigated the impact of fear effect,prey refuge and the additional food biomass on this model by numerical simulation. 展开更多
关键词 fear effect prey refuge additional food Lévy noise stochastic permanence
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Food additives and contaminants in infant foods: a critical review of their health risk, trends and recent developments
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作者 Swati Soni Anvil Jennifer W. +2 位作者 Christine Kurian Prapti Chakraborty Kuppusamy Alagesan Paari 《Food Production, Processing and Nutrition》 2024年第1期455-477,共23页
The infant food market has expanded rapidly over the past two decades.However,the industry faces significant chal-lenges,including concerns over the health effects of infant food additives and issues with food safety.... The infant food market has expanded rapidly over the past two decades.However,the industry faces significant chal-lenges,including concerns over the health effects of infant food additives and issues with food safety.However,new evidences suggest that certain food additives,such as those used to preserve and transport infant formula to keep it fresh for longer,should be avoided.Science into the effects of additives on human behavior makes up a sizable sector of the additives market.Problems such as hypernatremic dehydration,malnutrition,and obesity in infants are directly linked to faulty formula production.The Food and Drug Administration(FDA)has established the toxicity types and chemical tests necessary for evaluating the safety of food additives and GRAS(Generally Recognized as Safe)compounds.These tests are crucial in understanding the food safety aspects of food additives.The health effects of different types of food additives on infants are discussed in this context.The article gives an outline of various national and global agencies that provides recommendations and standards to gauge the quality of baby food.The immunological responses,allergic reaction pathways and other related health hazards among the infants and young children caused by the food additive are discussed in this article. 展开更多
关键词 Health risk Infant formula food food additives Immunological responses Child health
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Advances in Application of Non-aqueous Phase Enzymatic Catalysis in Food Additive Production 被引量:1
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作者 余泗莲 余琳 +4 位作者 余彬 孙文敬 刘长峰 杨梦依 崔凤杰 《Agricultural Science & Technology》 CAS 2013年第1期169-175,共7页
Non-aqueous phase enzymatic catalysis technology has been widely ap- plied in the area of food additives production. This paper reviewed the types of re- action medium of non-aqueous phase enzymatic catalysis reaction... Non-aqueous phase enzymatic catalysis technology has been widely ap- plied in the area of food additives production. This paper reviewed the types of re- action medium of non-aqueous phase enzymatic catalysis reaction, introduced the application of non-aqueous phase enzymatic catalysis technology in catalysis of L-ascorbic (isoascorbic) acid esters, short-chain acid esters, sugar esters, vitamin A esters, vi- tamin E esters, and other food additives, and finally predicted the prospects of non- aqueous phase enzymatic catalysis technology. 展开更多
关键词 Non-aqueous phase Enzymatic catalysis food additives Ester synthesis
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Facile preparation of nano-g-C_(3)N_(4)/UiO-66-NH_(2) composite as sorbent for high-efficient extraction and preconcentration of food colorants prior to HPLC analysis 被引量:6
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作者 Xiaowan Zhang Yixin Yang +5 位作者 Peige Qin Lizhen Han Wenli Zhu Shaofeng Duan Minghua Lu Zongwei Cai 《Chinese Chemical Letters》 SCIE CAS CSCD 2022年第2期903-906,共4页
In this work,the nano-g-C_(3)N_(4)/Ui O-66-NH_(2)composite was prepared by one-step solvothermal method.The as-prepared composite was characterized by scanning electron microscopy,Brunner-Emmet-Teller measurement,ener... In this work,the nano-g-C_(3)N_(4)/Ui O-66-NH_(2)composite was prepared by one-step solvothermal method.The as-prepared composite was characterized by scanning electron microscopy,Brunner-Emmet-Teller measurement,energy dispersive spectrometer,X-ray diffraction,and Fourier transform infrared spectroscopy.By using nano-g-C_(3)N_(4)/Ui O-66-NH_(2)composite as sorbent,a dispersive solid-phase extraction coupled with high-performance liquid chromatography was developed to sensitive analysis of food colorants including tartrazine,amaranth,carmine,sunset yellow,allura red and bright blue.The experiment parameters including the amount of sorbent,adsorption time,the p H of adsorption solution,desorption time,desorption solvent,the p H of desorption solution as well as the proportion between desorption solvent and buffer solvent were investigated.Under the optimized conditions,the limits of detection(S/N=3) and limits of quantitation (S/N=10) were determined in the ranges of 0.08-0.8 and 0.2-2.0 ng/m L,respectively.With the developed sample pretreatment method,carmine and brilliant blue were determined from blueberry juice by HPLC-DAD.The contents were calculated as 1.53μg/m L and0.17μg/mL,respectively. 展开更多
关键词 Nano-g-C_(3)N_(4)/Ui O-66-NH_(2)composite Metal-organic frameworks Dispersive solid-phase extraction Sample pretreatment food colorants food additives High-performance liquid chromatography
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The Revision of Aluminum-containing Food Additive Provisions in China 被引量:6
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作者 ZHANG Hong ZHANG Ji Yue +2 位作者 WANG Hua Li LUO Peng Jie ZHANG Jian Bo 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2016年第6期461-466,共6页
The aim of this study was to revise the provisions for aluminum-containing food additives in GB 2760-2011 (The National Food Safety Standard for Use of Food Additives), in order to reduce aluminum exposure among the... The aim of this study was to revise the provisions for aluminum-containing food additives in GB 2760-2011 (The National Food Safety Standard for Use of Food Additives), in order to reduce aluminum exposure among the Chinese population. According to the latest risk assessment results of JECFA and China on aluminum and the actual use of aluminum-containing food additives in certain products, the aluminum-containing food additive-related provisions in GB 2760-2011 were revised. Those revisions included narrowing down the applicable food categories and adjusting the maximum use level of aluminum potassium sulfate and aluminum ammonium sulfate, repealing nine aluminum-containing food additives in puffed food and repealing the use of sodium aluminum phosphate, sodium aluminosilicate and starch aluminum octenylsuccinate in all food. 展开更多
关键词 The Revision of Aluminum-containing food Additive Provisions in China GMP THAN
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Exploring economic viable species via assessing a tropic-specific microalgal collection
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作者 Chen MA Ni WANG +3 位作者 Yi XIN Qinhua GAN Wenxu ZHOU Yandu LU 《Journal of Oceanology and Limnology》 2025年第1期210-218,共9页
Locations around the equator provide unique habitats for microalgae presumably with exceptional vitality.To develop microalga-derived product systems,we previously created a(sub)tropical microalgal collection.In this ... Locations around the equator provide unique habitats for microalgae presumably with exceptional vitality.To develop microalga-derived product systems,we previously created a(sub)tropical microalgal collection.In this study,two Chlorella strains(MEM176 and MEM193),adaptive to typical tropical climate,were isolated from the collection.The production performance was evaluated where both strains showed a robust growth in high temperatures and light intensities.Specifically,the strains MEM176 and MEM193 produced 503.6-mg/(L·d)and 411.3-mg/(L·d)biomass,respectively,with high contents of proteins.Their commercial and nutritional values were emphasized by amino acid compositions(e.g.,proline,valine,and phenylalanine).Particularly,higher amounts of proline were revealed in MEM176(47.9 mg/g dry biomass(DW))and MEM193(47.9 and 59.2 mg/g DW)than available commercial strains.Compared with MEM193,MEM176 produced 129.7%more lipids in which unsaturated fatty acids(particularly linoleic acid andα-linolenic acid)account for 65%of the total lipids.Therefore,it is promising to explore the potential of these Chlorella strains as food additives via outdoor cultivation in tropical area,notably MEM176 that exhibits superiority as sources of essential amino acids and valuable fatty acids. 展开更多
关键词 CHLORELLA tropical species food additive MICROALGA
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Analysis of Stability and Hopf Bifurcation of a Delayed Predator-prey System with Fear and Additional Food
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作者 Yuan-fu SHAO Jin-xing ZHAO 《Acta Mathematicae Applicatae Sinica》 2026年第2期639-666,共28页
The delayed fear of prey towards predator and delayed gestation of predator usually affect the system dynamical behaviors.On the other hand,additional food supplement is a commen measure for people to preserve species... The delayed fear of prey towards predator and delayed gestation of predator usually affect the system dynamical behaviors.On the other hand,additional food supplement is a commen measure for people to preserve species from extinction and keep natural balance for continuous development in system control.Thus in this paper,we construct a predator-prey model with predator induced fear,additional food,Holling-II type functional response and time delays,and then generalize it to the random environment.Next,we establish some criteria of the asymptotical stability of equilibrium state,and stationary distribution for stochastic case.Considering the impacts of fear,additional food and time delays,we analyze the Hopf bifurcation of them.Finally by some numerical examples and graphical analysis,we intuitively validate such properties as stability,instability and Hopf bifurcation.Our findings reveal the significant impacts of fear,additional food and time delays on the system stability. 展开更多
关键词 fear effect additional food DELAY stability Hopf bifurcation
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Dietary additives interloping with the epigenetic network and human health:Implications in gut microbiota and endocrine toxicity
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作者 Shraddha Bhuiya Saumya Kaushik +2 位作者 Ragothaman Prathiviraj Joseph Selvin George Seghal Kiran 《Food Bioscience》 2025年第2期125-140,共16页
Food additives are substances added to food to modify sensory attributes or achieve technological goals.To regulate the usage of these additives,the WHO and FAO established a JECFA committee that meets to evaluate the... Food additives are substances added to food to modify sensory attributes or achieve technological goals.To regulate the usage of these additives,the WHO and FAO established a JECFA committee that meets to evaluate the usage limits of additives based on their effects.Upon consumption beyond the fixed limit,the body suffers from different toxicological effects,such as genotoxicity,developmental toxicity,reproductive toxicity and much more.However,their relationship with the endocrine system is less explored.With the advancement of food industries and increased consumer demands,the usage of synthetic additives is increasing without adequate knowledge of the effects of prolonged consumption on human health.Despite several adverse effects,some additives help to maintain the gut ecosystem,like nisin and algin,which are known for their probiotic and prebiotic effects.Therefore,this review explores the impact of food additives on human health,highlighting the dysbiosis of gut microbiota and endocrine system.The study also examines an epigenetic network and reveals essential diet additives for gut flora,emphasizing their direct relationship to genes and metabolic processes.This assessment was conducted to establish a link between epigenetic factors and outline future researches. 展开更多
关键词 food additives Gut microbiota Toxicological effects Endocrine system Probiotic
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Toxicity detection of sodium nitrite,borax and aluminum potassium sulfate using electrochemical method 被引量:9
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作者 Dengbin Yu Daming Yong Shaojun Dong 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2013年第4期785-790,共6页
Based on the inhibition effect on the respiratory chain activity of microorganisms by toxicants, an electrochemical method has been developed to measure the current variation of a mediator in the presence of microorga... Based on the inhibition effect on the respiratory chain activity of microorganisms by toxicants, an electrochemical method has been developed to measure the current variation of a mediator in the presence of microorganisms contacted with a toxicant. Microelectrode arrays were adopted in this study, which can accelerate the mass transfer rate of an anaiyte to the electrode and also increase the total current signal, resulting in an improvement in detection sensitivity. We selected Escherichia coli as the testee and the standard glucose- glutamic acid as an exogenous material. Under oxygen restriction, the experiments in the presence of toxicant were performed at optimum conditions (solution pH 7.0, 37℃ and reaction for 3 hr). The resulting solution was then separated from the suspended microorganisms and was measured by an electrochemical method, using ferricyanide as a mediator. The current signal obtained represents the reoxidation of ferrocyanide, which was transformed to inhibiting efficiency, IC50, as a quantitative measure of toxicity. The IC50 values measured were 410, 570 and 830 mg/L for sodium nitrite, borax and aluminum potassium sulfate, respectively. The results show that the toxicity sequence for these three food additives is consistent with the value reported by other methods. Furthermore, the order of damage degree to the microorganism was also observed to be: sodium nitrite 〉 borax 〉 aluminum potassium sulfate 〉 blank, according to the atomic force microscopy images of E. coli after being incubated for 3 hr with the toxic compound in buffer solutions. The electrochemical method is expected to be a sensitive and simple alternative to toxicity screening for chemical food additives. 展开更多
关键词 food additives sodium nitrite BORAX aluminum potassium sulfate microelectrode arrays
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Study on the Possibility of Mixed Water as a Drinking Water<br/>—From the Viewpoint of the Formation of Hydrogen-Rich Water 被引量:1
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作者 Akira Hiratsuka Yoshiro Yasuda 《Journal of Water Resource and Protection》 2021年第1期44-73,共30页
In exploring an autonomous independent water supply system, authors have realized the importance of the sustainable water supply utilizing regional features in isolated islands. This paper is further study from the pr... In exploring an autonomous independent water supply system, authors have realized the importance of the sustainable water supply utilizing regional features in isolated islands. This paper is further study from the previous one. This time we have narrowed down the mixing rate of mixed water. In this study, the mixed water less than 0.74% (blood concentration) has been prepared first, and then divided it into five kinds of the mixing rate of mixed water. And we have compared and examined the characteristics of the mixed water from the viewpoint of the relationship between salinity and pH, ORP and that of Dissolved Hydrogen, and examined the possibility of mixed water as a drinking water. As a result, we have obtained the new findings that suggest the possibility. 展开更多
关键词 Seawater RAINWATER Hydrogen-Rich Water Magnesium (Mg2+) food additives
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