Under the travelling wave transformation, Calogero-Degasperis-Focas equation is reduced to an ordinary differential equation. Using a symmetry group of one parameter, this ODE is reduced to a second-order linear inhom...Under the travelling wave transformation, Calogero-Degasperis-Focas equation is reduced to an ordinary differential equation. Using a symmetry group of one parameter, this ODE is reduced to a second-order linear inhomogeneous ODE. Furthermore, we apply the change of the variable and complete discrimination system for polynomial to solve the corresponding integrals and obtained the classification of all single travelling wave solutions to Calogero- Degasperis-Focas equation.展开更多
Cell|FOCAS:高通量筛选解析癌症中m^(6)A位点的功能异质性与表观转录调控网络N6-甲基腺苷(m^(6)A)是真核生物mRNA中最丰富的内部修饰,在基因表达调控中起关键作用。然而,传统的甲基转移酶敲除策略会改变全转录组的m^(6)A水平,导致难以...Cell|FOCAS:高通量筛选解析癌症中m^(6)A位点的功能异质性与表观转录调控网络N6-甲基腺苷(m^(6)A)是真核生物mRNA中最丰富的内部修饰,在基因表达调控中起关键作用。然而,传统的甲基转移酶敲除策略会改变全转录组的m^(6)A水平,导致难以解析单个特定m^(6)A位点的具体生物学功能。2025年12月31日,北京大学生命科学学院刘君与魏文胜课题组在Cell在线发表了题为“FOCAS:Transcriptome-wide screening of individual m6A sites functionally dissects epitranscriptomic control of gene expression in cancer”的研究论文(doi:10.1016/j.cell.2025.11.037)。展开更多
基金The project supported by Scientific Research and of Education Department of Heilongjiang Province of China under Grant No. 11511008
文摘Under the travelling wave transformation, Calogero-Degasperis-Focas equation is reduced to an ordinary differential equation. Using a symmetry group of one parameter, this ODE is reduced to a second-order linear inhomogeneous ODE. Furthermore, we apply the change of the variable and complete discrimination system for polynomial to solve the corresponding integrals and obtained the classification of all single travelling wave solutions to Calogero- Degasperis-Focas equation.
文摘Cell|FOCAS:高通量筛选解析癌症中m^(6)A位点的功能异质性与表观转录调控网络N6-甲基腺苷(m^(6)A)是真核生物mRNA中最丰富的内部修饰,在基因表达调控中起关键作用。然而,传统的甲基转移酶敲除策略会改变全转录组的m^(6)A水平,导致难以解析单个特定m^(6)A位点的具体生物学功能。2025年12月31日,北京大学生命科学学院刘君与魏文胜课题组在Cell在线发表了题为“FOCAS:Transcriptome-wide screening of individual m6A sites functionally dissects epitranscriptomic control of gene expression in cancer”的研究论文(doi:10.1016/j.cell.2025.11.037)。
