Solvent-free luminescent molecular liquids(LMLs), which exhibit nonvolatile fluidic nature and active optoelectronic properties, were widely used. For further development, we introduced siloxane units into AIE molecul...Solvent-free luminescent molecular liquids(LMLs), which exhibit nonvolatile fluidic nature and active optoelectronic properties, were widely used. For further development, we introduced siloxane units into AIE molecules, designed and synthesized TPE derivatives with siloxane side chains via facile Piers-Rubinsztajn reaction. The obtained AIE molecular liquids exhibit unique photophysical properties. Compared with the obtained alkyl TPE-solids, siloxane TPE show liquid state, which proves that the siloxane units have stronger liquefaction effect than alkyl. Viscosity test shows that siloxane TPE-liquids has far more lower viscosity and better fluidity than the long-chain alkyl molecular liquids in previous research. All those properties are attributed to the weak interaction between flexible molecular chains of siloxane. Besides,fluorescence test shows temperature responsiveness of siloxane TPE-liquids. We developed this lowviscosity nonvolatile AIE molecular liquid as green fluorescent ink.展开更多
Surgical tumor resection is a common approach to cancer treatment.India Ink tattoos are widely used to aid tumor resection by localizing and mapping the tumor edge at the surface.However,India Ink tattoos are easily o...Surgical tumor resection is a common approach to cancer treatment.India Ink tattoos are widely used to aid tumor resection by localizing and mapping the tumor edge at the surface.However,India Ink tattoos are easily obscured during electrosurgical resection,and fade in intensity over time.In this work,a novel near-infrared(NIR)fluorescent marker is introduced as an alternative.The NIR marker was made by mixing indocyanine green(ICG),biocompatible cyanoacrylate,and acetone.The marking strategy was evaluated in a chronic ex vivo feasibility study using porcine tissues,followed by a chronic in vivo mouse study while compared with India Ink.In both studies,signal-to-noise(SNR)ratios and dimensions of the NIR markers and/or India Ink over the study period were calculated and reported.Electrocautery was performed on the last day of the mouse study after mice were euthanized,and SNR ratios and dimensions were quantified and compared.Biopsy was performed at all injection sites and slides were examined by a pathologist.The proposed NIR marker achieved(i)consistent visibility in the 26-day feasibility study and(ii)improved durability,visibility,and biocompatibility when compared to traditional India Ink over the six-week period in an in vivo mouse model.These effects persist after electrocautery whereas the India Ink markers were obscured.The use of a NIR fluorescent presurgical marking strategy has the potential for intraoperative tracking during long-term treatment protocols.展开更多
Rare earth nanomaterials exhibit remarkable characteristics,including real-time responsiveness,luminescence stability,and multicolor emission capabilities.Herein,NaYbF_(4):x%Tb,y%Eu@NaYF_(4)core-shell structured nanop...Rare earth nanomaterials exhibit remarkable characteristics,including real-time responsiveness,luminescence stability,and multicolor emission capabilities.Herein,NaYbF_(4):x%Tb,y%Eu@NaYF_(4)core-shell structured nanoparticles(CSNP)were synthesized with distinct fluorescence under both ultraviolet(UV)and near-infrared(NIR)excitation.It can be uniformly mixed with a transparent ink solution and loaded into ink cartridges to print customized graphics on copy papers.The graphics cannot be recognized under normal visible light,and the concealed information with high resolution can only be exposed under specific excitation light.Combining with cryptography,it facilitates the implementation of advanced information encryption techniques.Consequently,the innovative fluorescent ink materials hold significant promise for enhancing anti-counterfeiting and information encryption.展开更多
Since the discovery of aggregation induced emission(AIE)phenomenon,various stimuli-responsive materials have been rapidly developed,but there are still great challenges in the application of ink printing due to the ba...Since the discovery of aggregation induced emission(AIE)phenomenon,various stimuli-responsive materials have been rapidly developed,but there are still great challenges in the application of ink printing due to the bad water solubility.In this research,a new cationic amphiphilic TPE-functionalized pyridine salt(TPE-OTs)was designed,which shows good water solubility and hydrochromic properties.The optical properties of the compound have been studied,which is equipped with the typical AIEE characteristics and TICT effect.The compound can self-assemble to form aggregates with a particle size of about 30 nm in water.What is more,the compound is responsive to the environmental humidity,whose fluorescent color changes from green to yellow as the humidity gradually increased.Based on this characteristic,we applied it to the fluorescent anti-counterfeiting ink,realizing the protection and encryption of information.展开更多
Fluorescent carbon dots(CDs)have been identified as potential nanosensors and attracted tremendous research interests in wide areas including anti-counterfeiting,environmental and biological sensing and imaging in con...Fluorescent carbon dots(CDs)have been identified as potential nanosensors and attracted tremendous research interests in wide areas including anti-counterfeiting,environmental and biological sensing and imaging in considering of the attractive optical properties.In this work,we present a CDs based fluorescent sensor from polyvinylpyrrolidone,citric acid,and methionine as precursors by hydrothermal approach.The selective quantifying of Fe^(3+)and ascorbic acid(AA)are based on the fluorescent on-off-on process,in which the fluorescent quenching is induced by the coordination of the Fe^(3+)on the surface of the CDs,while the fluorescence recovery is mainly attributed to redox reaction between Fe^(3+)and AA,breaking the coordination and bringing the fluorescence back.Inspired by the good water solubility and biocompatibility,significant photostability,superior photobleaching resistance as well as high selectivity,sensitivity,and interference immunity,which are constructed mainly from the N,S-doping and methionine surface functionalization,the CDs have not only been employed as fluorescence ink in multiple anticounterfeiting printing and confidential document writing or transmitting,but also been developed as promising fluorescence sensors in solution and solid by CDs doped test strips and hydrogels for effectively monitoring and removing of Fe^(3+)and AA in environmental aqueous solution.The CDs have been also implemented as effective diagnostic candidates for imaging and tracking of Fe^(3+)and AA in living cells,accelerating the understanding of their function and importance in related biological processes for the prevention and treatment specific diseases.展开更多
基金supported by the National Natural Science Foundation of China (No. 21602124)Natural Science Foundation ofShandong Province (No. ZR2016BQ11)the Young Scholars Program of Shandong University (No. 2018WLJH40)。
文摘Solvent-free luminescent molecular liquids(LMLs), which exhibit nonvolatile fluidic nature and active optoelectronic properties, were widely used. For further development, we introduced siloxane units into AIE molecules, designed and synthesized TPE derivatives with siloxane side chains via facile Piers-Rubinsztajn reaction. The obtained AIE molecular liquids exhibit unique photophysical properties. Compared with the obtained alkyl TPE-solids, siloxane TPE show liquid state, which proves that the siloxane units have stronger liquefaction effect than alkyl. Viscosity test shows that siloxane TPE-liquids has far more lower viscosity and better fluidity than the long-chain alkyl molecular liquids in previous research. All those properties are attributed to the weak interaction between flexible molecular chains of siloxane. Besides,fluorescence test shows temperature responsiveness of siloxane TPE-liquids. We developed this lowviscosity nonvolatile AIE molecular liquid as green fluorescent ink.
基金This work is spported by the National Istitutes of Health under award rumbers 1RO1BB020610 and R21EB024707spprted by the Intramua Research Progam of the National Insites of Health,Natioial Cancer Istitutet Center for Cancer Reearch.
文摘Surgical tumor resection is a common approach to cancer treatment.India Ink tattoos are widely used to aid tumor resection by localizing and mapping the tumor edge at the surface.However,India Ink tattoos are easily obscured during electrosurgical resection,and fade in intensity over time.In this work,a novel near-infrared(NIR)fluorescent marker is introduced as an alternative.The NIR marker was made by mixing indocyanine green(ICG),biocompatible cyanoacrylate,and acetone.The marking strategy was evaluated in a chronic ex vivo feasibility study using porcine tissues,followed by a chronic in vivo mouse study while compared with India Ink.In both studies,signal-to-noise(SNR)ratios and dimensions of the NIR markers and/or India Ink over the study period were calculated and reported.Electrocautery was performed on the last day of the mouse study after mice were euthanized,and SNR ratios and dimensions were quantified and compared.Biopsy was performed at all injection sites and slides were examined by a pathologist.The proposed NIR marker achieved(i)consistent visibility in the 26-day feasibility study and(ii)improved durability,visibility,and biocompatibility when compared to traditional India Ink over the six-week period in an in vivo mouse model.These effects persist after electrocautery whereas the India Ink markers were obscured.The use of a NIR fluorescent presurgical marking strategy has the potential for intraoperative tracking during long-term treatment protocols.
基金supported by the National Natural Science Foundation of China(Nos.22101257 and 52103189)Foundation of Zhejiang Sci-Tech University Shengzhou Innovation Research Institute(No.SYY2024B000001).
文摘Rare earth nanomaterials exhibit remarkable characteristics,including real-time responsiveness,luminescence stability,and multicolor emission capabilities.Herein,NaYbF_(4):x%Tb,y%Eu@NaYF_(4)core-shell structured nanoparticles(CSNP)were synthesized with distinct fluorescence under both ultraviolet(UV)and near-infrared(NIR)excitation.It can be uniformly mixed with a transparent ink solution and loaded into ink cartridges to print customized graphics on copy papers.The graphics cannot be recognized under normal visible light,and the concealed information with high resolution can only be exposed under specific excitation light.Combining with cryptography,it facilitates the implementation of advanced information encryption techniques.Consequently,the innovative fluorescent ink materials hold significant promise for enhancing anti-counterfeiting and information encryption.
基金financially supported by the National Natural Science Foundation of China(Nos.52173102,21774070 and 21602124)Fluorine Silicone Materials Collaborative Fund of Shandong Provincial Natural Science Foundation(Nos.ZR2021LFG001,ZR2021LFG007)the Young Scholars Program of Shandong University(No.2018WLJH40)。
文摘Since the discovery of aggregation induced emission(AIE)phenomenon,various stimuli-responsive materials have been rapidly developed,but there are still great challenges in the application of ink printing due to the bad water solubility.In this research,a new cationic amphiphilic TPE-functionalized pyridine salt(TPE-OTs)was designed,which shows good water solubility and hydrochromic properties.The optical properties of the compound have been studied,which is equipped with the typical AIEE characteristics and TICT effect.The compound can self-assemble to form aggregates with a particle size of about 30 nm in water.What is more,the compound is responsive to the environmental humidity,whose fluorescent color changes from green to yellow as the humidity gradually increased.Based on this characteristic,we applied it to the fluorescent anti-counterfeiting ink,realizing the protection and encryption of information.
基金supported by the National Natural Science Foundation of China(Nos.22171223,22179107,22077099,and 21807087)the Technology Innovation Leading Program of Shaanxi(No.2020TG−031)+2 种基金the Shaanxi Provincial Natural Science Fund Project(No.2018JQ2061)the Xi’an City Science and Technology Project(Nos.2020KJRC011 and 2019218214GXRC018CG019−GXYD18.4)the Outstanding Youth Science Fund of Xi’an University of Science and Technology(No.2018YQ3-14).
文摘Fluorescent carbon dots(CDs)have been identified as potential nanosensors and attracted tremendous research interests in wide areas including anti-counterfeiting,environmental and biological sensing and imaging in considering of the attractive optical properties.In this work,we present a CDs based fluorescent sensor from polyvinylpyrrolidone,citric acid,and methionine as precursors by hydrothermal approach.The selective quantifying of Fe^(3+)and ascorbic acid(AA)are based on the fluorescent on-off-on process,in which the fluorescent quenching is induced by the coordination of the Fe^(3+)on the surface of the CDs,while the fluorescence recovery is mainly attributed to redox reaction between Fe^(3+)and AA,breaking the coordination and bringing the fluorescence back.Inspired by the good water solubility and biocompatibility,significant photostability,superior photobleaching resistance as well as high selectivity,sensitivity,and interference immunity,which are constructed mainly from the N,S-doping and methionine surface functionalization,the CDs have not only been employed as fluorescence ink in multiple anticounterfeiting printing and confidential document writing or transmitting,but also been developed as promising fluorescence sensors in solution and solid by CDs doped test strips and hydrogels for effectively monitoring and removing of Fe^(3+)and AA in environmental aqueous solution.The CDs have been also implemented as effective diagnostic candidates for imaging and tracking of Fe^(3+)and AA in living cells,accelerating the understanding of their function and importance in related biological processes for the prevention and treatment specific diseases.
