To observe the effect of Fufang Jisheng Liujin Gao (复方寄生流浸膏 Compound Mistletoe Fluidextract) on blood pressure in the spontaneous hypertensive rats (SHR) and the renal hypertensive dogs (RHD). Methods: T...To observe the effect of Fufang Jisheng Liujin Gao (复方寄生流浸膏 Compound Mistletoe Fluidextract) on blood pressure in the spontaneous hypertensive rats (SHR) and the renal hypertensive dogs (RHD). Methods: The blood pressure-decreasing effects of single administration and 14-day consecutive administration of Compound Mistletoe Fluidextract (CMF) in SHR and RHD were investigated and compared with that of Niuhuang Jiangya Wan (牛黄降压丸 Bezoar Hypertension-relieving Pills). Results: Both single administration and 14-day consecutive administration of CMF had significant hypotensive effects in SHR and RHD. Conclusion: The hypotensive action of CMF is gradual, but lasts for a longer period, with a dose-effect relationship in a range of doses.展开更多
文摘To observe the effect of Fufang Jisheng Liujin Gao (复方寄生流浸膏 Compound Mistletoe Fluidextract) on blood pressure in the spontaneous hypertensive rats (SHR) and the renal hypertensive dogs (RHD). Methods: The blood pressure-decreasing effects of single administration and 14-day consecutive administration of Compound Mistletoe Fluidextract (CMF) in SHR and RHD were investigated and compared with that of Niuhuang Jiangya Wan (牛黄降压丸 Bezoar Hypertension-relieving Pills). Results: Both single administration and 14-day consecutive administration of CMF had significant hypotensive effects in SHR and RHD. Conclusion: The hypotensive action of CMF is gradual, but lasts for a longer period, with a dose-effect relationship in a range of doses.