The behavior of three-dimensional bond fluctuation model chains tethered on an adsorbing fiat surface was simulated by the Monte Carlo method.The dependence of the number of surface contacts M on the interaction stren...The behavior of three-dimensional bond fluctuation model chains tethered on an adsorbing fiat surface was simulated by the Monte Carlo method.The dependence of the number of surface contacts M on the interaction strengthεand the chain length N was investigated by a finite-size scaling law M = N;[a;+a;N;κ+ O((N;κ);)]forεnear the critical adsorption pointε;,i.e.,κ=（ε-ε;）/ε;closes to 0.The critical adsorption point was estimated to beε;=0.93,and the exponentsφ= 0.49 and l/v= 0.57.展开更多
The kagome lattice,characterized by its network of cornersharing triangles,provides an excellent platform for studying various novel quantum phenomena.The recently discovered kagome metal AV3Sb5(A=K,Rb,Cs)[1]garners s...The kagome lattice,characterized by its network of cornersharing triangles,provides an excellent platform for studying various novel quantum phenomena.The recently discovered kagome metal AV3Sb5(A=K,Rb,Cs)[1]garners significant attention for its unique properties,including an unconventional charge density wave(CDW)and superconductivity(SC)[2],as well as the interplay between CDW and SC[3].展开更多
In order to address environmental pollution and resource depletion caused by traditional power generation,this paper proposes an adaptive iterative dynamic-balance optimization algorithm that integrates the Improved D...In order to address environmental pollution and resource depletion caused by traditional power generation,this paper proposes an adaptive iterative dynamic-balance optimization algorithm that integrates the Improved Dung Beetle Optimizer(IDBO)with VariationalMode Decomposition(VMD).The IDBO-VMD method is designed to enhance the accuracy and efficiency of wind-speed time-series decomposition and to effectively smooth photovoltaic power fluctuations.This study innovatively improves the traditional variational mode decomposition(VMD)algorithm,and significantly improves the accuracy and adaptive ability of signal decomposition by IDBO selfoptimization of key parameters K and a.On this basis,Fourier transform technology is used to define the boundary point between high frequency and low frequency signals,and a targeted energy distribution strategy is proposed:high frequency fluctuations are allocated to supercapacitors to quickly respond to transient power fluctuations;Lowfrequency components are distributed to lead-carbon batteries,optimizing long-term energy storage and scheduling efficiency.This strategy effectively improves the response speed and stability of the energy storage system.The experimental results demonstrate that the IDBO-VMD algorithm markedly outperforms traditional methods in both decomposition accuracy and computational efficiency.Specifically,it effectively reduces the charge–discharge frequency of the battery,prolongs battery life,and optimizes the operating ranges of the state-of-charge(SOC)for both leadcarbon batteries and supercapacitors.In addition,the energy management strategy based on the algorithm not only improves the overall energy utilization efficiency of the system,but also shows excellent performance in the dynamic management and intelligent scheduling of renewable energy generation.展开更多
Plants encounter dynamic light environments in natural field conditions,and species differ in their physiological and biochemical mechanisms for acclimating to fluctuating light(FL).The manner in which soybean(Glycine...Plants encounter dynamic light environments in natural field conditions,and species differ in their physiological and biochemical mechanisms for acclimating to fluctuating light(FL).The manner in which soybean(Glycine max(L.) Merr.) coordinates multiple physiological adjustments to FL remains poorly understood.This study assessed the effects of FL on soybean morphology and photosynthetic traits by examining changes in photosynthetic gas exchange parameters and chlorophyll(Chl) a fluorescence under alternating high-and low-light conditions.Results indicated that soybeans exposed to FL exhibited reduced dry matter accumulation,smaller and thinner leaves,and a lower Chl a/Chl b levels-characteristics typically associated with plants grown under continuous low-light.Despite these morphological similarities,their photosynthetic gas exchange rates and photosynthetic capacity were maintained at levels comparable to those under steady high light,unlike plants grown under constant low-light.Thus,acclimation to FL is distinct from adaptation to sustained low-light conditions.Correlation analyses revealed that the decline in carbon assimilation under FL primarily stemmed from two factors:the slow recovery of stomatal conductance upon transition to high light and the delayed relaxation of nonphotochemical quenching when light intensity decreased.Therefore,the reduction in carbon assimilation under FL cannot be attributed to low-light phase adjustments but rather reflects a lag in photosynthetic responsiveness to changing light conditions.展开更多
Raw water temperature can fluctuate significantly throughout the year,with peaks above 30℃in summer and below 15℃in winter.Traditional desalination systems(e.g.,reverse osmosis,RO)face challenges under these varying...Raw water temperature can fluctuate significantly throughout the year,with peaks above 30℃in summer and below 15℃in winter.Traditional desalination systems(e.g.,reverse osmosis,RO)face challenges under these varying temperature conditions.Specifically,while the RO system performs well under high temperatures,its efficiency decreases sharply at lower temperatures.Membrane capacitive deionization(MCDI)is considered as an emergent and promising technology for brackish water desalination.While plenty of studies have been devoted to investigating the impacts of raw water properties(e.g.,salinity,coexisting ions,and natural organic matter)on MCDI performance,the role of water temperatures during the desalination remains under-explored.In this study,we first tested and determined the optimized MCDI operation parameters,such as the cell voltage and feedwater flow rate.Key findings showed that MCDI’s salt removal efficiency remains unaffected by feedwater temperature fluctuations.However,as feedwater temperature increases from 15℃to 40℃,the specific energy consumption for desalination slightly rises by 16.3%,and current efficiency drops by 14.1%.Compared to RO systems,the resilience of MCDI to temperature fluctuations makes it a preferable choice for brackish water treatment in areas with a large temperature difference.展开更多
Thermal fluctuations have been found to significantly influence the dissipation range of turbulence,an effect beyond the scope of the classical Navier-Stokes equations.In this study,we investigate their impact on turb...Thermal fluctuations have been found to significantly influence the dissipation range of turbulence,an effect beyond the scope of the classical Navier-Stokes equations.In this study,we investigate their impact on turbulent channel flow by numerically solving the fluctuating hydrodynamic equations.Simulation results confirm theoretical predictions that the energy spectrum,dominated by thermal fluctuations,follows a k2 power law.When thermal fluctuations reach sufficient intensity,they disrupt the dominant turbulent structures responsible for most of the kinetic energy,leading to a reduction in large-scale spectral energy.Additionally,thermal fluctuations increase wall skin friction by modifying mean velocity profiles.The injected energy amplifies Reynolds normal stresses while maintaining the magnitude of Reynolds shear stress.Furthermore,thermal fluctuations enhance the symmetry and homogeneity of velocity fluctuations while reducing their intermittency.Despite these effects,the balance between kinetic energy production and dissipation,including both turbulent and thermal contributions,remains preserved.展开更多
AIM:To compare spontaneous brain regional activities between diabetic vitreous hemorrhage patients(DVHs)and healthy controls(HCs).METHODS:Thirty-two DVHs and 32 HCs were enrolled in this study.Baseline demographic and...AIM:To compare spontaneous brain regional activities between diabetic vitreous hemorrhage patients(DVHs)and healthy controls(HCs).METHODS:Thirty-two DVHs and 32 HCs were enrolled in this study.Baseline demographic and vision data were compared between groups using an independent sample t-test.Resting-state functional magnetic resonance imaging(rs-fMRI)was used in all participants.fMRI data was obtained and analyzed using MRIcro and SPM8 software.Fractional amplitude of low-frequency fluctuation(fALFF)technology was used to measure regional spontaneous brain activity,and sensitivity was tested using receiver operating characteristic curves(ROCs).The fALFF values were analyzed using REST software and two-sample t-tests were used to compare values between groups.Hospital anxiety and depression scale(HADS)score was assessed in DVHs and Pearson’s correlation was used to test relationships between mean fALFF value and both HADS score and duration of DVH.RESULTS:Except for the best-corrected visual acuity(BCVA)in both eyes,which showed a statistically significant difference(P<0.05),there were no statistically significant differences in the other indicators(P>0.05)between the HCs and DVHs group.Compared with controls,fALFF value was higher in DVH in cerebellum posterior lobe(CPL)and lower in right anterior cingulate cortex(ACC)and right medial orbitofrontal cortex(OFC).In DVH patients,mean fALFF value of CPL was positively correlated with HADS score and duration of diabetes.However,no such correlation was found,for right ACC or right medial OFC.DVH may lead to abnormal activities in certain brain regions related to visual control and mood.CONCLUSION:Visual impairment caused by DVH may lead to adjustment in regional visual brain activities and may be related to depression or reward system processing in some brain regions.展开更多
Freezing of gait is a significant and debilitating motor symptom often observed in individuals with Parkinson's disease.Resting-state functional magnetic resonance imaging,along with its multi-level feature indice...Freezing of gait is a significant and debilitating motor symptom often observed in individuals with Parkinson's disease.Resting-state functional magnetic resonance imaging,along with its multi-level feature indices,has provided a fresh perspective and valuable insight into the study of freezing of gait in Parkinson's disease.It has been revealed that Parkinson's disease is accompanied by widespread irregularities in inherent brain network activity.However,the effective integration of the multi-level indices of resting-state functional magnetic resonance imaging into clinical settings for the diagnosis of freezing of gait in Parkinson's disease remains a challenge.Although previous studies have demonstrated that radiomics can extract optimal features as biomarkers to identify or predict diseases,a knowledge gap still exists in the field of freezing of gait in Parkinson's disease.This cross-sectional study aimed to evaluate the ability of radiomics features based on multi-level indices of resting-state functional magnetic resonance imaging,along with clinical features,to distinguish between Parkinson's disease patients with and without freezing of gait.We recruited 28 patients with Parkinson's disease who had freezing of gait(15 men and 13 women,average age 63 years)and 30 patients with Parkinson's disease who had no freezing of gait(16 men and 14 women,average age 64 years).Magnetic resonance imaging scans were obtained using a 3.0T scanner to extract the mean amplitude of low-frequency fluctuations,mean regional homogeneity,and degree centrality.Neurological and clinical characteristics were also evaluated.We used the least absolute shrinkage and selection operator algorithm to extract features and established feedforward neural network models based solely on resting-state functional magnetic resonance imaging indicators.We then performed predictive analysis of three distinct groups based on resting-state functional magnetic resonance imaging indicators indicators combined with clinical features.Subsequently,we conducted 100 additional five-fold cross-validations to determine the most effective model for each classification task and evaluated the performance of the model using the area under the receiver operating characteristic curve.The results showed that when differentiating patients with Parkinson's disease who had freezing of gait from those who did not have freezing of gait,or from healthy controls,the models using only the mean regional homogeneity values achieved the highest area under the receiver operating characteristic curve values of 0.750(with an accuracy of 70.9%)and 0.759(with an accuracy of 65.3%),respectively.When classifying patients with Parkinson's disease who had freezing of gait from those who had no freezing of gait,the model using the mean amplitude of low-frequency fluctuation values combined with two clinical features achieved the highest area under the receiver operating characteristic curve of 0.847(with an accuracy of 74.3%).The most significant features for patients with Parkinson's disease who had freezing of gait were amplitude of low-frequency fluctuation alterations in the left parahippocampal gyrus and two clinical characteristics:Montreal Cognitive Assessment and Hamilton Depression Scale scores.Our findings suggest that radiomics features derived from resting-state functional magnetic resonance imaging indices and clinical information can serve as valuable indices for the identification of freezing of gait in Parkinson's disease.展开更多
Self-excited longitudinal combustion instabilities were investigated in a hypergolic liquid bipropellant combustor, which applied single dual-swirl coaxial injector. Hot-fire tests were conducted for four different in...Self-excited longitudinal combustion instabilities were investigated in a hypergolic liquid bipropellant combustor, which applied single dual-swirl coaxial injector. Hot-fire tests were conducted for four different injector geometries, while extensive tests on injection conditions were carried out for each injector geometry. The synchronous measurement of the pressure and heat release rate was applied, successfully capturing the process of the pressure and heat release rate enhanced coupling and developing into in-phase oscillation. By calculating Rayleigh index at the head and middle section of the chamber, it is shown that Rayleigh index of the middle section is even higher than that of the head, indicating a long heat release zone. When the combustion instability occurs, the pressure in propellant manifolds also oscillates with the same frequency and lags behind the oscillation in the combustor. Compared to the oscillation in the outer injector manifold, the oscillation in the inner injector manifold shows a higher correlation with that in the chamber in amplitude and phase. Based on numerical simulations of the multiphase cold flow inside the injector and combustion process in the chamber, it is found that injector geometries affect longitudinal combustion instability by changing spray cone angle. The spray with small cone angle is more sensitive to the modulation of longitudinal pressure wave in combustion simulations, which is more likely to excite the longitudinal combustion instability. Meanwhile, the combustion instability may be related to the pulsating coherent structure generated by the spray fluctuation, which is determined by injection conditions. Besides, a positive feedback closed-loop system associated with the active fluctuation and passive oscillation of the spray is believed to excite and sustain the longitudinal combustion instability.展开更多
The impact of extreme temperatures on the health of individuals in different organizations remains uncertain.We employed stratified analyses to examine the impacts of summer(April-September)daily maximum temperatures ...The impact of extreme temperatures on the health of individuals in different organizations remains uncertain.We employed stratified analyses to examine the impacts of summer(April-September)daily maximum temperatures and winter(October-March)daily minimum temperatures on blood pressure and lipid profiles across government staff,com-pany employees,and researchers.We examined 209,477 physical examination records from a physical examination center in the First Affiliated Hospital of USTC from 2017 to 2021.Employing a segmented regression model within the frame-work of generalized linear regression(GLM),we examined the causal impact of extreme temperatures on health outcomes.Additionally,sensitivity analyses were conducted via distributed lag nonlinear models(DLNMs),with a focus on ob-serving the long-term effects over a period of 21 days.Our findings indicate that government staff face increased health risks during extremely low temperatures,regardless of the season.Compared with participants experiencing median tem-peratures,government staff exposed to extremely low temperatures(below the 10th percentile,below 24℃)in the sum-mer presented maximum increases of 2.32 mmHg(95%CI:1.542-3.098)in diastolic blood pressure and 6.481 mmHg(95%CI:5.368-7.594)in systolic blood pressure.In winter,government staff exposed to temperatures below the 10th per-centile(below 1℃)demonstrated maximum increases of 0.278 mmol/L(95%CI:0.210-0.346)in total cholesterol,0.153 mmol/L(95%CI:0.032-0.274)in triglycerides,and 0.077 mmol/L(95%CI:0.192-0.134)in low-density lipoprotein.Conversely,warm winters benefit company employees,whereas researchers exhibit lower sensitivity to temperature changes in winter.The maximum temperatures in summer and minimum temperatures in winter had greater impacts on in-dividuals.Small temperature fluctuations impact health more than large changes do.Notably,both the maximum and min-imum temperatures were better predictors of health outcomes than the daily average temperature was.Blood pressure con-sistently displayed significant associations with temperature across all three groups,with extremely low temperatures in-creasing the risk and extremely high temperatures reducing it.However,the relationship between temperature and blood lipids is complex.展开更多
Recent advances in two-dimensional layered systems have greatly enriched electronic transport studies, particularly in inter-layer Coulomb drag research. Here, systematic transport measurements were conducted in graph...Recent advances in two-dimensional layered systems have greatly enriched electronic transport studies, particularly in inter-layer Coulomb drag research. Here, systematic transport measurements were conducted in graphene-based electronic double-layer structures, revealing giant yet reproducible drag fluctuations at cryogenic temperatures. These fluctuations' characteristics, including amplitude and peak/valley spacing, are mainly determined by the drag layer's carrier dynamics rather than the drive layer's, resulting in violation of the Onsager reciprocity relation. Notably, the drag fluctuations remain observable up to 35 K, far exceeding universal conductance fluctuations within individual layers. This suggests enhanced phase coherence in inter-layer drag compared to single-layer transport, as further confirmed by quantitative analysis of auto-correlation fields of fluctuations under magnetic fields. Our findings provide new insights into quantum interference effects and their interplay with Coulomb interactions in solids. The observations of significant drag fluctuations could potentially help address chaotic signals between nearby components in nanoscale devices.展开更多
BACKGROUND Very late-onset schizophrenia-like psychosis(VLOSLP)is a subtype of schizophrenia spectrum disorders in which individuals experience psychotic symptoms for the first time after the age of 60.The incidence o...BACKGROUND Very late-onset schizophrenia-like psychosis(VLOSLP)is a subtype of schizophrenia spectrum disorders in which individuals experience psychotic symptoms for the first time after the age of 60.The incidence of VLOSLP shows a linear relationship with increasing age.However,no studies have reported alterations in spontaneous brain activity among VLOSLP patients and their correlation with cognitive function and clinical symptoms.AIM To explore VLOSLP brain activity and correlations with cognitive function and clinical symptoms using resting-state functional magnetic resonance imaging.METHODS This study included 33 VLOSLP patients and 34 healthy controls.The cognitive assessment utilized the Mini Mental State Examination,Montreal Cognitive Assessment,and the Repeatable Battery for the Assessment of Neuropsychological Status(RBANS).Clinical characteristic acquisition was performed via the Positive and Negative Syndrome Scale(PANSS).All participants were scanned via resting-state functional magnetic resonance imaging,and the data were processed using amplitude of low-frequency fluctuations(ALFF),fractional ALFF(fALFF),regional homogeneity,and voxelmirrored homotopic connectivity(VMHC).RESULTS The VLOSLP group presented decreased ALFF values in the left cuneus,right precuneus,right precentral gyrus,and left paracentral lobule;increased fALFF values in the left caudate nucleus;decreased fALFF values in the right calcarine fissure and surrounding cortex(CAL)and right precuneus;increased regional homogeneity values in the right putamen;and decreased VMHC values in the bilateral CAL,bilateral superior temporal gyrus,and bilateral cuneus.In the VLOSLP group,ALFF values in the right precuneus were negatively correlated with Mini Mental State Examination score and PANSS positive subscale score,and VMHC values in the bilateral CAL were negatively correlated with the RBANS total score,RBANS delayed memory score,and PANSS positive subscale score.CONCLUSION The changes of brain activity in VLOSLP are concentrated in the right precuneus and bilateral CAL regions,which may be associated with cognitive impairment and clinically positive symptoms.展开更多
Tunnel-induced noise amplification has become a major constraint for high-speed trains.This study employs a 1/10 scale three-coach high-speed train model,using the improved delayed detached eddy simulation(IDDES)metho...Tunnel-induced noise amplification has become a major constraint for high-speed trains.This study employs a 1/10 scale three-coach high-speed train model,using the improved delayed detached eddy simulation(IDDES)method coupled with the perturbed convective wave model to investigate the unsteady flow evolution,aerodynamic noise source distribution,and near-field acoustic characteristics of high-speed trains under open-air and tunnel conditions.The results show that the blocking effect of the tunnel wall enhances flow compression,increases local velocity,and aggravates flow disturbances and pressure fluctuations near the pantograph and tail car.In the tunnel,the total sound source energy reaches 1.14×10^(12)N^(2)/s^(2),5.26 times higher than in open air,with significant increases in the tail car,bogies,and pantograph.Bogie noise concentrates in the 50 to 1000 Hz range,while pantograph noise dominates from 1500 to 2500 Hz.Tunnel conditions further enhance peak distributions in the low and medium frequency bands.Although pressure disturbances on the train surface are mainly dominated by hydrodynamic effects,the radiated acoustic energy of the sound pressure levels on the roof and side surfaces is amplified by 33.3 and 22.6 times,far exceeding hydrodynamic energy amplification factors of 8.6 and 6.3.The study reveals coupled flow and acoustic mechanisms in tunnels,supporting noise reduction design for high-speed trains.展开更多
Intracellular redox homeostasis is of indispensable importance in pathophysiology.In order to maintain the balance of the redox state within the cell,reactive oxygen species(ROS)and reactive sulfur species(RSS)react a...Intracellular redox homeostasis is of indispensable importance in pathophysiology.In order to maintain the balance of the redox state within the cell,reactive oxygen species(ROS)and reactive sulfur species(RSS)react and transform with each other,and their levels also directly reflect the degree of oxidative stress and disease.Hypochlorous acid(HClO)and cysteine(Cys)usually co-exist in organisms,interacting with each other in many important physiological processes and synergistically maintaining the dynamic redox balance in the body.To understand the relevance and pathophysiological effects of these two signaling molecules in oxidative stress,unique fluorescence imaging tools are required.Herein,we designed and developed a dual-channel fluorescent probe HP,for the individual and continuous detection of HClO and Cys.This probe could simultaneously monitor the changes in the concentrations of HClO and Cys in cells,and was characterized by a fast response,high sensitivity and high selectivity,especially compared with glutathione(GSH)and homocysteine(Hcy),the probe had a good specificity for Cys.Importantly,probe HP successfully observed dynamic changes in HCl O-and Cys-mediated redox status in the oxygenglucose deprivation/reperfusion(OGD/R)model of HeLa cells and dynamically monitored fluctuations in endogenous HClO levels in lipopolysaccharides(LPS)-induced peritonitis mice.展开更多
Open cavities with different door-opening angles are investigated using high-speed schlieren visualization and dynamic pressure measurements in hypersonic flow with a freestream Mach number of 6.With the help of numer...Open cavities with different door-opening angles are investigated using high-speed schlieren visualization and dynamic pressure measurements in hypersonic flow with a freestream Mach number of 6.With the help of numerical simulations,the shear layer deformation and pressure increase in the cavities due to the impingement of the door-leading-edge shocks are identified via comparison with those in the cavity without doors.As the door-opening angle decreases from 90°,the shear layer above the forepart of the cavity is gradually raised by the high pressure in the cavity.When the door-opening angle decreases to 30°and 15°,the boundary layer on the upstream flat plate of the cavity separates,and separation shock is observed.The doors enhance the instability of the cavity flow and increase the pressure fluctuations in the cavities.A new oscillation pattern,referred to as coupled oscillation,is observed in the cases with separation on the upstream flat plate,in which the separation shock oscillates at the same dominant frequency as the flow inside the cavity.Compared with the cavity without doors,this coupled oscillation causes a lower oscillation frequency and a larger overall sound pressure level.Cross-correlation analyses between pressure signals indicate that the disturbances generated at the trailing edge of the cavity can propagate to the separation on the upstream flat plate and cause coupled oscillation of the separation shock.The fundamental frequencies of the coupled oscillations can be normalized to approximately the same Strouhal number as that of the cavity without doors.These findings support that the oscillation mechanisms of hypersonic cavities without and with doors are primarily dominated by acoustic feedback.展开更多
The process of riming significantly impacts the microphysical characteristics of clouds.This study uses aircraft and radar observation data in stratiform clouds with convection embedded that occurred in the central an...The process of riming significantly impacts the microphysical characteristics of clouds.This study uses aircraft and radar observation data in stratiform clouds with convection embedded that occurred in the central and southern regions of North China on 22 May 2017.The microphysical structural characteristics and processes near the embedded convection core and in the stratiform cloud are analyzed comparatively.Particular attention is given to the effect of riming on the microphysical properties near the upper boundary of the melting layer and to the factors influencing riming efficiency.The collaborative observations reveal that the particle size distributions observed near the convection core and in the stratiform region are close,while the particle properties like habit and riming degree are quite different.Above the melting layer,larger plate-like ice particles and supercooled water droplets(D>50μm)are more abundant near the convective core,leading to higher collision efficiencies between ice particles and supercooled water droplets.Larger fluctuation amplitudes of vertical airflow near the convective core also contribute to the increased riming activity and the formation of more heavily rimed particles,such as graupel.Furthermore,in situ measurements from airborne probes also revealed that above the melting layer,the riming process involves two stages:the mass of snow crystals grows as supercooled droplets merge internally without changing size,followed by external freezing that significantly enlarges the crystals.展开更多
Understanding the complex interactions between urbanization and ecosystem services(ESs)is crucial for optimiz ing planning policies and achieving sustainable urban management.While previous research has largely focuse...Understanding the complex interactions between urbanization and ecosystem services(ESs)is crucial for optimiz ing planning policies and achieving sustainable urban management.While previous research has largely focused on highly urbanized areas,little attention has been given to the phased effect of progressive urbanization on ES networks.This study proposes a conceptual framework that utilizes the network method and space-time replace ment to examine the effect of urbanization on the complex relationships among ESs at different stages,with a particular emphasis on the progressive evolution of the process.We apply this framework to the Horqin area,a typical eco-fragile area in China.Results demonstrate that the connectivity of the ES synergy network exhibits a non-stationary characteristic,initially increasing,then decreasing,and subsequently strengthening.Meanwhile,its modularity shows a rising trend during periods of accelerated urbanization.The performance of the trade off network displays the opposite pattern.Additionally,we observe a gradual replacement of provisioning and regulation services by cultural services in terms of dominance in the synergy network as urbanization advances.By providing guidance for identifying key planning initiatives and implementing ecological protection policies at different stages of development,this study contributes a pathway that can inform development strategies in other regions undergoing progressive urbanization.展开更多
Implementing additive manufacturing to NiTi(Nitinol)alloys typically enables a preferred<001>_(B2) tex-ture along the building direction.Unfortunately,this growth orientation always possesses a high criti-cal st...Implementing additive manufacturing to NiTi(Nitinol)alloys typically enables a preferred<001>_(B2) tex-ture along the building direction.Unfortunately,this growth orientation always possesses a high criti-cal stress level to induce the martensitic transformation and experiences premature failure before the formation of martensite during tensile testing.By utilizing in situ characterization technologies,in this study,we demonstrate that by fabricating a NiTi sample with complete<001>_(B2) texture using wire-fed electron beam directed energy deposition,a sluggish martensitic transformation can be achieved to re-tard the initiation of fracture under tensile loading.To discern the origins of this tensile response,we combine experiments with molecular dynamics simulations to systematically analyze the micro-scale de-tails on how internal lattice defects can select the variety of martensite variants.Using both quasi in situ transmission electron microscopy analysis and calculations of the different atomic configurations,our results indicate that the pre-existing precipitates and accumulated dislocation defects,rather than columnar boundaries,can have a positive influence on the sluggish formation of variants that can cou-ple with plastic deformation within a much wider stress interval.Specifically,only the variant favored by both internal strain/stress fluctuations around local defects and external tensile load will overcome the high-energy transition barrier of<001>_(B2)-oriented tension to nucleate and grow sluggishly.The cur-rent findings not only show how the mechanical responses can be controlled in additively manufactured NiTi alloys with<001>_(B2) texture,but also regard this understanding to be a step forward in decoding the salient underlying mechanisms for the correlating texture,defects,and phase transformation of these functional materials.展开更多
Background:An arterial stiffness is an indicator of many cardiovascular diseases.The temporal position of systolic blood pressure(BP)on aorta pulse waveform is assumed to gradually shift on the waveform in response to...Background:An arterial stiffness is an indicator of many cardiovascular diseases.The temporal position of systolic blood pressure(BP)on aorta pulse waveform is assumed to gradually shift on the waveform in response to increasing/decreasing vascular stiffness.The animal model of rats and invasive methods that cannot be used in humans was applied to test the assumption on arterial pulse waveform(APW)of anesthetized rat.The aim of this study was to characterize the temporal movement of diastolic and systolic pressures on the APW of anesthetized rats during increasing/decreasing vascular stiffness.Methods:The right jugular vein of anesthetized normotensive and spontaneously hypertensive rats was cannulated for intravascular administration of vascularly active compounds to alter systolic pressure and vascular stiffness.The left carotid artery was cannulated to detect APW,from which numerous APW parameters were evaluated.Results:During increases/decreases in systolic BP or stiffness,the temporal position of diastolic BP of individual heartbeats di-gitally shifted on the APW between two temporal positions~8–12 ms apart,and the temporal position of systolic BP on the APW did not gradually shift during increases/decreases in vascular stiffness,as expected,but oscillated between constant di-gital,tri-gital,or tetra-gital temporal positions.Conclusions:Introducing new APW parameters,n-gital systolic BP fluctuations on rat APW were found.Fluctuations in n-gital were approximately constant during large changes in systolic pressure despite significant changes in augmentation index and cardiovascular stiffness,which may challenge the assumption of a gradual temporal location of systolic pressure on rat APW under these conditions.展开更多
This research examines the hard-rock aquifer system within the Nagavathi River Basin(NRB)South India,by evaluating seasonal fluctuations in groundwater composition during the pre-monsoon(PRM)and post-monsoon(POM)perio...This research examines the hard-rock aquifer system within the Nagavathi River Basin(NRB)South India,by evaluating seasonal fluctuations in groundwater composition during the pre-monsoon(PRM)and post-monsoon(POM)periods.Seasonal variations significantly influence the groundwater quality,particularly fluoride(F−)concentrations,which can fluctuate due to changes in recharge,evaporation,and anthropogenic activities.This study assesses the dynamics of F−levels in PRM and POM seasons,and identifies elevated health risks using USEPA guidelines and Monte Carlo Simulations(MCS).Groundwater in the study area exhibits alkaline pH,with NaCl and Ca-Na-HCO_(3) facies increasing in the POM season due to intensified ion exchange and rock-water interactions,as indicated in Piper and Gibb’s diagrams.Correlation and dendrogram analyses indicate that F−contamination is from geogenic and anthropogenic sources.F−levels exceed the WHO limit(1.5 mg/L)in 51 PRM and 28 POM samples,affecting 371.74 km^(2) and 203.05 km^(2),respectively.Geochemical processes,including mineral weathering,cation exchange,evaporation,and dilution,are identified through CAI I&II.Health risk assessments reveal that HQ values>1 in 78%of children,73%of teens,and 68%of adults during PRM,decreasing to 45%,40%,and 38%,respectively,in POM.MCS show maximum HQ values of 5.67(PRM)and 4.73(POM)in children,with all age groups facing significant risks from fluoride ingestion.Managed Aquifer Recharge(MAR)is recommended in this study to minimize F−contamination,ensuring safe drinking water for the community.展开更多
基金supported by the National Natural Science Foundation of China (No.20674074).
文摘The behavior of three-dimensional bond fluctuation model chains tethered on an adsorbing fiat surface was simulated by the Monte Carlo method.The dependence of the number of surface contacts M on the interaction strengthεand the chain length N was investigated by a finite-size scaling law M = N;[a;+a;N;κ+ O((N;κ);)]forεnear the critical adsorption pointε;,i.e.,κ=（ε-ε;）/ε;closes to 0.The critical adsorption point was estimated to beε;=0.93,and the exponentsφ= 0.49 and l/v= 0.57.
基金support from the National Key R&D Program of China(2021YFA1401800 and 2021YFA1400202)the National Natural Science Foundation of China(12141404)+7 种基金the Natural Science Foundation of Shanghai(22ZR1479700 and 23XD1422200)Shaofeng Duan acknowledged support from the China Postdoctoral Science Foundation(2022M722108)the China National Postdoctoral Program for Innovative Talents(BX20230216)the National Natural Science Foundation of China(12304178)Yanfeng Guo acknowledged the National Key R&D Program of China(2023YFA1406100)the Double First-Class Initiative Fund of ShanghaiTech Universitysupport from the National Key R&D Program of China(2022YFA1402400 and 2021YFA1400100)the National Natural Science Foundation of China(12074248).
文摘The kagome lattice,characterized by its network of cornersharing triangles,provides an excellent platform for studying various novel quantum phenomena.The recently discovered kagome metal AV3Sb5(A=K,Rb,Cs)[1]garners significant attention for its unique properties,including an unconventional charge density wave(CDW)and superconductivity(SC)[2],as well as the interplay between CDW and SC[3].
基金funded by the Institute of Smart Energy,Huaiyin Institute of Technology,under Grant No.HIT-ISE-2024-07.
文摘In order to address environmental pollution and resource depletion caused by traditional power generation,this paper proposes an adaptive iterative dynamic-balance optimization algorithm that integrates the Improved Dung Beetle Optimizer(IDBO)with VariationalMode Decomposition(VMD).The IDBO-VMD method is designed to enhance the accuracy and efficiency of wind-speed time-series decomposition and to effectively smooth photovoltaic power fluctuations.This study innovatively improves the traditional variational mode decomposition(VMD)algorithm,and significantly improves the accuracy and adaptive ability of signal decomposition by IDBO selfoptimization of key parameters K and a.On this basis,Fourier transform technology is used to define the boundary point between high frequency and low frequency signals,and a targeted energy distribution strategy is proposed:high frequency fluctuations are allocated to supercapacitors to quickly respond to transient power fluctuations;Lowfrequency components are distributed to lead-carbon batteries,optimizing long-term energy storage and scheduling efficiency.This strategy effectively improves the response speed and stability of the energy storage system.The experimental results demonstrate that the IDBO-VMD algorithm markedly outperforms traditional methods in both decomposition accuracy and computational efficiency.Specifically,it effectively reduces the charge–discharge frequency of the battery,prolongs battery life,and optimizes the operating ranges of the state-of-charge(SOC)for both leadcarbon batteries and supercapacitors.In addition,the energy management strategy based on the algorithm not only improves the overall energy utilization efficiency of the system,but also shows excellent performance in the dynamic management and intelligent scheduling of renewable energy generation.
基金supported by the National Key Research and Development Program of China (2023YFF1001504)the National Natural Science Foundation of China (32071963)+2 种基金the National Key Research and Development Program of China (2022YFD2300902)the Guangxi Key Research and Development Program of China (GuikeAB23026107)the Chengdu Science and Technology Project,China (2023-YF08-00003-SN)。
文摘Plants encounter dynamic light environments in natural field conditions,and species differ in their physiological and biochemical mechanisms for acclimating to fluctuating light(FL).The manner in which soybean(Glycine max(L.) Merr.) coordinates multiple physiological adjustments to FL remains poorly understood.This study assessed the effects of FL on soybean morphology and photosynthetic traits by examining changes in photosynthetic gas exchange parameters and chlorophyll(Chl) a fluorescence under alternating high-and low-light conditions.Results indicated that soybeans exposed to FL exhibited reduced dry matter accumulation,smaller and thinner leaves,and a lower Chl a/Chl b levels-characteristics typically associated with plants grown under continuous low-light.Despite these morphological similarities,their photosynthetic gas exchange rates and photosynthetic capacity were maintained at levels comparable to those under steady high light,unlike plants grown under constant low-light.Thus,acclimation to FL is distinct from adaptation to sustained low-light conditions.Correlation analyses revealed that the decline in carbon assimilation under FL primarily stemmed from two factors:the slow recovery of stomatal conductance upon transition to high light and the delayed relaxation of nonphotochemical quenching when light intensity decreased.Therefore,the reduction in carbon assimilation under FL cannot be attributed to low-light phase adjustments but rather reflects a lag in photosynthetic responsiveness to changing light conditions.
基金supported by the National Natural Science Foundation of China(Nos.52370090,52300016)China Postdoctoral Science Foundation(Nos.2023M733379,2024M753122).
文摘Raw water temperature can fluctuate significantly throughout the year,with peaks above 30℃in summer and below 15℃in winter.Traditional desalination systems(e.g.,reverse osmosis,RO)face challenges under these varying temperature conditions.Specifically,while the RO system performs well under high temperatures,its efficiency decreases sharply at lower temperatures.Membrane capacitive deionization(MCDI)is considered as an emergent and promising technology for brackish water desalination.While plenty of studies have been devoted to investigating the impacts of raw water properties(e.g.,salinity,coexisting ions,and natural organic matter)on MCDI performance,the role of water temperatures during the desalination remains under-explored.In this study,we first tested and determined the optimized MCDI operation parameters,such as the cell voltage and feedwater flow rate.Key findings showed that MCDI’s salt removal efficiency remains unaffected by feedwater temperature fluctuations.However,as feedwater temperature increases from 15℃to 40℃,the specific energy consumption for desalination slightly rises by 16.3%,and current efficiency drops by 14.1%.Compared to RO systems,the resilience of MCDI to temperature fluctuations makes it a preferable choice for brackish water treatment in areas with a large temperature difference.
基金supported by the National Natural Science Foundation of China(Grant Nos.12202437,12172352,and 12388101)the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB0500300)+1 种基金the Fundamental Research Funds for the Central Universities(Grant No.WK2090000086)the Key Laboratory of Cross Domain Flight Interdisciplinary technology(Grant No.2023ZY0101).
文摘Thermal fluctuations have been found to significantly influence the dissipation range of turbulence,an effect beyond the scope of the classical Navier-Stokes equations.In this study,we investigate their impact on turbulent channel flow by numerically solving the fluctuating hydrodynamic equations.Simulation results confirm theoretical predictions that the energy spectrum,dominated by thermal fluctuations,follows a k2 power law.When thermal fluctuations reach sufficient intensity,they disrupt the dominant turbulent structures responsible for most of the kinetic energy,leading to a reduction in large-scale spectral energy.Additionally,thermal fluctuations increase wall skin friction by modifying mean velocity profiles.The injected energy amplifies Reynolds normal stresses while maintaining the magnitude of Reynolds shear stress.Furthermore,thermal fluctuations enhance the symmetry and homogeneity of velocity fluctuations while reducing their intermittency.Despite these effects,the balance between kinetic energy production and dissipation,including both turbulent and thermal contributions,remains preserved.
基金Supported by National Natural Science Foundation of China(No.82160195,No.82460203)Zhejiang Traditional Chinese Medicine Science and Technology Plan Project(No.2025ZR172).
文摘AIM:To compare spontaneous brain regional activities between diabetic vitreous hemorrhage patients(DVHs)and healthy controls(HCs).METHODS:Thirty-two DVHs and 32 HCs were enrolled in this study.Baseline demographic and vision data were compared between groups using an independent sample t-test.Resting-state functional magnetic resonance imaging(rs-fMRI)was used in all participants.fMRI data was obtained and analyzed using MRIcro and SPM8 software.Fractional amplitude of low-frequency fluctuation(fALFF)technology was used to measure regional spontaneous brain activity,and sensitivity was tested using receiver operating characteristic curves(ROCs).The fALFF values were analyzed using REST software and two-sample t-tests were used to compare values between groups.Hospital anxiety and depression scale(HADS)score was assessed in DVHs and Pearson’s correlation was used to test relationships between mean fALFF value and both HADS score and duration of DVH.RESULTS:Except for the best-corrected visual acuity(BCVA)in both eyes,which showed a statistically significant difference(P<0.05),there were no statistically significant differences in the other indicators(P>0.05)between the HCs and DVHs group.Compared with controls,fALFF value was higher in DVH in cerebellum posterior lobe(CPL)and lower in right anterior cingulate cortex(ACC)and right medial orbitofrontal cortex(OFC).In DVH patients,mean fALFF value of CPL was positively correlated with HADS score and duration of diabetes.However,no such correlation was found,for right ACC or right medial OFC.DVH may lead to abnormal activities in certain brain regions related to visual control and mood.CONCLUSION:Visual impairment caused by DVH may lead to adjustment in regional visual brain activities and may be related to depression or reward system processing in some brain regions.
基金supported by the National Natural Science Foundation of China,No.82071909(to GF)the Natural Science Foundation of Liaoning Province,No.2023-MS-07(to HL)。
文摘Freezing of gait is a significant and debilitating motor symptom often observed in individuals with Parkinson's disease.Resting-state functional magnetic resonance imaging,along with its multi-level feature indices,has provided a fresh perspective and valuable insight into the study of freezing of gait in Parkinson's disease.It has been revealed that Parkinson's disease is accompanied by widespread irregularities in inherent brain network activity.However,the effective integration of the multi-level indices of resting-state functional magnetic resonance imaging into clinical settings for the diagnosis of freezing of gait in Parkinson's disease remains a challenge.Although previous studies have demonstrated that radiomics can extract optimal features as biomarkers to identify or predict diseases,a knowledge gap still exists in the field of freezing of gait in Parkinson's disease.This cross-sectional study aimed to evaluate the ability of radiomics features based on multi-level indices of resting-state functional magnetic resonance imaging,along with clinical features,to distinguish between Parkinson's disease patients with and without freezing of gait.We recruited 28 patients with Parkinson's disease who had freezing of gait(15 men and 13 women,average age 63 years)and 30 patients with Parkinson's disease who had no freezing of gait(16 men and 14 women,average age 64 years).Magnetic resonance imaging scans were obtained using a 3.0T scanner to extract the mean amplitude of low-frequency fluctuations,mean regional homogeneity,and degree centrality.Neurological and clinical characteristics were also evaluated.We used the least absolute shrinkage and selection operator algorithm to extract features and established feedforward neural network models based solely on resting-state functional magnetic resonance imaging indicators.We then performed predictive analysis of three distinct groups based on resting-state functional magnetic resonance imaging indicators indicators combined with clinical features.Subsequently,we conducted 100 additional five-fold cross-validations to determine the most effective model for each classification task and evaluated the performance of the model using the area under the receiver operating characteristic curve.The results showed that when differentiating patients with Parkinson's disease who had freezing of gait from those who did not have freezing of gait,or from healthy controls,the models using only the mean regional homogeneity values achieved the highest area under the receiver operating characteristic curve values of 0.750(with an accuracy of 70.9%)and 0.759(with an accuracy of 65.3%),respectively.When classifying patients with Parkinson's disease who had freezing of gait from those who had no freezing of gait,the model using the mean amplitude of low-frequency fluctuation values combined with two clinical features achieved the highest area under the receiver operating characteristic curve of 0.847(with an accuracy of 74.3%).The most significant features for patients with Parkinson's disease who had freezing of gait were amplitude of low-frequency fluctuation alterations in the left parahippocampal gyrus and two clinical characteristics:Montreal Cognitive Assessment and Hamilton Depression Scale scores.Our findings suggest that radiomics features derived from resting-state functional magnetic resonance imaging indices and clinical information can serve as valuable indices for the identification of freezing of gait in Parkinson's disease.
基金support from the National Natural Science Foundation of China(No.12002386).
文摘Self-excited longitudinal combustion instabilities were investigated in a hypergolic liquid bipropellant combustor, which applied single dual-swirl coaxial injector. Hot-fire tests were conducted for four different injector geometries, while extensive tests on injection conditions were carried out for each injector geometry. The synchronous measurement of the pressure and heat release rate was applied, successfully capturing the process of the pressure and heat release rate enhanced coupling and developing into in-phase oscillation. By calculating Rayleigh index at the head and middle section of the chamber, it is shown that Rayleigh index of the middle section is even higher than that of the head, indicating a long heat release zone. When the combustion instability occurs, the pressure in propellant manifolds also oscillates with the same frequency and lags behind the oscillation in the combustor. Compared to the oscillation in the outer injector manifold, the oscillation in the inner injector manifold shows a higher correlation with that in the chamber in amplitude and phase. Based on numerical simulations of the multiphase cold flow inside the injector and combustion process in the chamber, it is found that injector geometries affect longitudinal combustion instability by changing spray cone angle. The spray with small cone angle is more sensitive to the modulation of longitudinal pressure wave in combustion simulations, which is more likely to excite the longitudinal combustion instability. Meanwhile, the combustion instability may be related to the pulsating coherent structure generated by the spray fluctuation, which is determined by injection conditions. Besides, a positive feedback closed-loop system associated with the active fluctuation and passive oscillation of the spray is believed to excite and sustain the longitudinal combustion instability.
基金supported by the National Natural Science Foundation of China(72072169)the Fundamental Re-search Funds for the Central Universities(YD2040002015).
文摘The impact of extreme temperatures on the health of individuals in different organizations remains uncertain.We employed stratified analyses to examine the impacts of summer(April-September)daily maximum temperatures and winter(October-March)daily minimum temperatures on blood pressure and lipid profiles across government staff,com-pany employees,and researchers.We examined 209,477 physical examination records from a physical examination center in the First Affiliated Hospital of USTC from 2017 to 2021.Employing a segmented regression model within the frame-work of generalized linear regression(GLM),we examined the causal impact of extreme temperatures on health outcomes.Additionally,sensitivity analyses were conducted via distributed lag nonlinear models(DLNMs),with a focus on ob-serving the long-term effects over a period of 21 days.Our findings indicate that government staff face increased health risks during extremely low temperatures,regardless of the season.Compared with participants experiencing median tem-peratures,government staff exposed to extremely low temperatures(below the 10th percentile,below 24℃)in the sum-mer presented maximum increases of 2.32 mmHg(95%CI:1.542-3.098)in diastolic blood pressure and 6.481 mmHg(95%CI:5.368-7.594)in systolic blood pressure.In winter,government staff exposed to temperatures below the 10th per-centile(below 1℃)demonstrated maximum increases of 0.278 mmol/L(95%CI:0.210-0.346)in total cholesterol,0.153 mmol/L(95%CI:0.032-0.274)in triglycerides,and 0.077 mmol/L(95%CI:0.192-0.134)in low-density lipoprotein.Conversely,warm winters benefit company employees,whereas researchers exhibit lower sensitivity to temperature changes in winter.The maximum temperatures in summer and minimum temperatures in winter had greater impacts on in-dividuals.Small temperature fluctuations impact health more than large changes do.Notably,both the maximum and min-imum temperatures were better predictors of health outcomes than the daily average temperature was.Blood pressure con-sistently displayed significant associations with temperature across all three groups,with extremely low temperatures in-creasing the risk and extremely high temperatures reducing it.However,the relationship between temperature and blood lipids is complex.
基金supported by the National Natural Science Foundation of China (Grant Nos.12474051 and 92165201)the Chinese Academy of Sciences Project for Young Scientists in Basic Research (Grant No.YSBR-046)+1 种基金the National Key Research and Development Program of China (Grant No.2023YFA1406300)the Anhui Provincial Natural Science Foundation (Grant Nos.2308085J11 and2308085QA14)。
文摘Recent advances in two-dimensional layered systems have greatly enriched electronic transport studies, particularly in inter-layer Coulomb drag research. Here, systematic transport measurements were conducted in graphene-based electronic double-layer structures, revealing giant yet reproducible drag fluctuations at cryogenic temperatures. These fluctuations' characteristics, including amplitude and peak/valley spacing, are mainly determined by the drag layer's carrier dynamics rather than the drive layer's, resulting in violation of the Onsager reciprocity relation. Notably, the drag fluctuations remain observable up to 35 K, far exceeding universal conductance fluctuations within individual layers. This suggests enhanced phase coherence in inter-layer drag compared to single-layer transport, as further confirmed by quantitative analysis of auto-correlation fields of fluctuations under magnetic fields. Our findings provide new insights into quantum interference effects and their interplay with Coulomb interactions in solids. The observations of significant drag fluctuations could potentially help address chaotic signals between nearby components in nanoscale devices.
基金Supported by Wuxi Municipal Health Commission Major Project,No.202107and Wuxi Taihu Talent Project,No.WXTTP 2021.
文摘BACKGROUND Very late-onset schizophrenia-like psychosis(VLOSLP)is a subtype of schizophrenia spectrum disorders in which individuals experience psychotic symptoms for the first time after the age of 60.The incidence of VLOSLP shows a linear relationship with increasing age.However,no studies have reported alterations in spontaneous brain activity among VLOSLP patients and their correlation with cognitive function and clinical symptoms.AIM To explore VLOSLP brain activity and correlations with cognitive function and clinical symptoms using resting-state functional magnetic resonance imaging.METHODS This study included 33 VLOSLP patients and 34 healthy controls.The cognitive assessment utilized the Mini Mental State Examination,Montreal Cognitive Assessment,and the Repeatable Battery for the Assessment of Neuropsychological Status(RBANS).Clinical characteristic acquisition was performed via the Positive and Negative Syndrome Scale(PANSS).All participants were scanned via resting-state functional magnetic resonance imaging,and the data were processed using amplitude of low-frequency fluctuations(ALFF),fractional ALFF(fALFF),regional homogeneity,and voxelmirrored homotopic connectivity(VMHC).RESULTS The VLOSLP group presented decreased ALFF values in the left cuneus,right precuneus,right precentral gyrus,and left paracentral lobule;increased fALFF values in the left caudate nucleus;decreased fALFF values in the right calcarine fissure and surrounding cortex(CAL)and right precuneus;increased regional homogeneity values in the right putamen;and decreased VMHC values in the bilateral CAL,bilateral superior temporal gyrus,and bilateral cuneus.In the VLOSLP group,ALFF values in the right precuneus were negatively correlated with Mini Mental State Examination score and PANSS positive subscale score,and VMHC values in the bilateral CAL were negatively correlated with the RBANS total score,RBANS delayed memory score,and PANSS positive subscale score.CONCLUSION The changes of brain activity in VLOSLP are concentrated in the right precuneus and bilateral CAL regions,which may be associated with cognitive impairment and clinically positive symptoms.
基金Project(2020YFA0710902)supported by the National Key Research and Development Program of ChinaProject(12172308)supported by the National Natural Science Foundation of ChinaProject(2025RVL-QY-T24)supported by the Independent Project of State Key Laboratory of Rail Transit Vehicle System,China。
文摘Tunnel-induced noise amplification has become a major constraint for high-speed trains.This study employs a 1/10 scale three-coach high-speed train model,using the improved delayed detached eddy simulation(IDDES)method coupled with the perturbed convective wave model to investigate the unsteady flow evolution,aerodynamic noise source distribution,and near-field acoustic characteristics of high-speed trains under open-air and tunnel conditions.The results show that the blocking effect of the tunnel wall enhances flow compression,increases local velocity,and aggravates flow disturbances and pressure fluctuations near the pantograph and tail car.In the tunnel,the total sound source energy reaches 1.14×10^(12)N^(2)/s^(2),5.26 times higher than in open air,with significant increases in the tail car,bogies,and pantograph.Bogie noise concentrates in the 50 to 1000 Hz range,while pantograph noise dominates from 1500 to 2500 Hz.Tunnel conditions further enhance peak distributions in the low and medium frequency bands.Although pressure disturbances on the train surface are mainly dominated by hydrodynamic effects,the radiated acoustic energy of the sound pressure levels on the roof and side surfaces is amplified by 33.3 and 22.6 times,far exceeding hydrodynamic energy amplification factors of 8.6 and 6.3.The study reveals coupled flow and acoustic mechanisms in tunnels,supporting noise reduction design for high-speed trains.
基金the National Natural Science Foundation of China(Nos.22207069,22325703,22377071,22074084)Research Project Supported by Shanxi Scholarship Council of China(No.2022-002)+2 种基金the Shanxi Province Science Foundation(Nos.20210302124012,202203021221009)Key R&D and transformation plan of Qinghai Province(No.2020-GX-101)2023 Graduate Innovation Project of Shanxi University。
文摘Intracellular redox homeostasis is of indispensable importance in pathophysiology.In order to maintain the balance of the redox state within the cell,reactive oxygen species(ROS)and reactive sulfur species(RSS)react and transform with each other,and their levels also directly reflect the degree of oxidative stress and disease.Hypochlorous acid(HClO)and cysteine(Cys)usually co-exist in organisms,interacting with each other in many important physiological processes and synergistically maintaining the dynamic redox balance in the body.To understand the relevance and pathophysiological effects of these two signaling molecules in oxidative stress,unique fluorescence imaging tools are required.Herein,we designed and developed a dual-channel fluorescent probe HP,for the individual and continuous detection of HClO and Cys.This probe could simultaneously monitor the changes in the concentrations of HClO and Cys in cells,and was characterized by a fast response,high sensitivity and high selectivity,especially compared with glutathione(GSH)and homocysteine(Hcy),the probe had a good specificity for Cys.Importantly,probe HP successfully observed dynamic changes in HCl O-and Cys-mediated redox status in the oxygenglucose deprivation/reperfusion(OGD/R)model of HeLa cells and dynamically monitored fluctuations in endogenous HClO levels in lipopolysaccharides(LPS)-induced peritonitis mice.
基金supported by the National Natural Science Foundation of China(Nos.12172354,12388101,U21B6003)the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB0620201).
文摘Open cavities with different door-opening angles are investigated using high-speed schlieren visualization and dynamic pressure measurements in hypersonic flow with a freestream Mach number of 6.With the help of numerical simulations,the shear layer deformation and pressure increase in the cavities due to the impingement of the door-leading-edge shocks are identified via comparison with those in the cavity without doors.As the door-opening angle decreases from 90°,the shear layer above the forepart of the cavity is gradually raised by the high pressure in the cavity.When the door-opening angle decreases to 30°and 15°,the boundary layer on the upstream flat plate of the cavity separates,and separation shock is observed.The doors enhance the instability of the cavity flow and increase the pressure fluctuations in the cavities.A new oscillation pattern,referred to as coupled oscillation,is observed in the cases with separation on the upstream flat plate,in which the separation shock oscillates at the same dominant frequency as the flow inside the cavity.Compared with the cavity without doors,this coupled oscillation causes a lower oscillation frequency and a larger overall sound pressure level.Cross-correlation analyses between pressure signals indicate that the disturbances generated at the trailing edge of the cavity can propagate to the separation on the upstream flat plate and cause coupled oscillation of the separation shock.The fundamental frequencies of the coupled oscillations can be normalized to approximately the same Strouhal number as that of the cavity without doors.These findings support that the oscillation mechanisms of hypersonic cavities without and with doors are primarily dominated by acoustic feedback.
基金supported by the National Natural Science Foundation of China(Grant No.42025501)the Natural Science Foundation of Hebei Province(Grant No.D2024304015)+4 种基金the Fundamental Research Funds for the Central Universities,including Grant No.020714380217the Cemac“GeoX”Interdisciplinary Program(Grant No.020714380210)the Open Grants of the Key Laboratory of Radar Meteorology,China Meteorological Administration(Grant No.2023LRM-B05)the Hebei Meteorological Service Scientific Research and Development Project(Grant No.23ky08)the Open Research Program of the State Key Laboratory of Severe Weather(Grant No.2023LASW-A01)。
文摘The process of riming significantly impacts the microphysical characteristics of clouds.This study uses aircraft and radar observation data in stratiform clouds with convection embedded that occurred in the central and southern regions of North China on 22 May 2017.The microphysical structural characteristics and processes near the embedded convection core and in the stratiform cloud are analyzed comparatively.Particular attention is given to the effect of riming on the microphysical properties near the upper boundary of the melting layer and to the factors influencing riming efficiency.The collaborative observations reveal that the particle size distributions observed near the convection core and in the stratiform region are close,while the particle properties like habit and riming degree are quite different.Above the melting layer,larger plate-like ice particles and supercooled water droplets(D>50μm)are more abundant near the convective core,leading to higher collision efficiencies between ice particles and supercooled water droplets.Larger fluctuation amplitudes of vertical airflow near the convective core also contribute to the increased riming activity and the formation of more heavily rimed particles,such as graupel.Furthermore,in situ measurements from airborne probes also revealed that above the melting layer,the riming process involves two stages:the mass of snow crystals grows as supercooled droplets merge internally without changing size,followed by external freezing that significantly enlarges the crystals.
基金supported by the National Natural Science Foundation Projects of China(Grant No.42071284).
文摘Understanding the complex interactions between urbanization and ecosystem services(ESs)is crucial for optimiz ing planning policies and achieving sustainable urban management.While previous research has largely focused on highly urbanized areas,little attention has been given to the phased effect of progressive urbanization on ES networks.This study proposes a conceptual framework that utilizes the network method and space-time replace ment to examine the effect of urbanization on the complex relationships among ESs at different stages,with a particular emphasis on the progressive evolution of the process.We apply this framework to the Horqin area,a typical eco-fragile area in China.Results demonstrate that the connectivity of the ES synergy network exhibits a non-stationary characteristic,initially increasing,then decreasing,and subsequently strengthening.Meanwhile,its modularity shows a rising trend during periods of accelerated urbanization.The performance of the trade off network displays the opposite pattern.Additionally,we observe a gradual replacement of provisioning and regulation services by cultural services in terms of dominance in the synergy network as urbanization advances.By providing guidance for identifying key planning initiatives and implementing ecological protection policies at different stages of development,this study contributes a pathway that can inform development strategies in other regions undergoing progressive urbanization.
基金supported by the National Natural Science Foundation of China(Nos.52101037,52401040 and 52171034)the Postdoctoral Fellowship Program of CPSF(No.GZB20230944)with the computational resources provided by LvLiang Cloud Comput-ing Center.
文摘Implementing additive manufacturing to NiTi(Nitinol)alloys typically enables a preferred<001>_(B2) tex-ture along the building direction.Unfortunately,this growth orientation always possesses a high criti-cal stress level to induce the martensitic transformation and experiences premature failure before the formation of martensite during tensile testing.By utilizing in situ characterization technologies,in this study,we demonstrate that by fabricating a NiTi sample with complete<001>_(B2) texture using wire-fed electron beam directed energy deposition,a sluggish martensitic transformation can be achieved to re-tard the initiation of fracture under tensile loading.To discern the origins of this tensile response,we combine experiments with molecular dynamics simulations to systematically analyze the micro-scale de-tails on how internal lattice defects can select the variety of martensite variants.Using both quasi in situ transmission electron microscopy analysis and calculations of the different atomic configurations,our results indicate that the pre-existing precipitates and accumulated dislocation defects,rather than columnar boundaries,can have a positive influence on the sluggish formation of variants that can cou-ple with plastic deformation within a much wider stress interval.Specifically,only the variant favored by both internal strain/stress fluctuations around local defects and external tensile load will overcome the high-energy transition barrier of<001>_(B2)-oriented tension to nucleate and grow sluggishly.The cur-rent findings not only show how the mechanical responses can be controlled in additively manufactured NiTi alloys with<001>_(B2) texture,but also regard this understanding to be a step forward in decoding the salient underlying mechanisms for the correlating texture,defects,and phase transformation of these functional materials.
基金supported by funding from ERA4Health:InterHeart 2025 to L.Tomasova and the VEGA Grant Agency of the Slovak Republic(grant number 2/0138/25 to A.Misak and 2/0066/23 to L.Tomasova).
文摘Background:An arterial stiffness is an indicator of many cardiovascular diseases.The temporal position of systolic blood pressure(BP)on aorta pulse waveform is assumed to gradually shift on the waveform in response to increasing/decreasing vascular stiffness.The animal model of rats and invasive methods that cannot be used in humans was applied to test the assumption on arterial pulse waveform(APW)of anesthetized rat.The aim of this study was to characterize the temporal movement of diastolic and systolic pressures on the APW of anesthetized rats during increasing/decreasing vascular stiffness.Methods:The right jugular vein of anesthetized normotensive and spontaneously hypertensive rats was cannulated for intravascular administration of vascularly active compounds to alter systolic pressure and vascular stiffness.The left carotid artery was cannulated to detect APW,from which numerous APW parameters were evaluated.Results:During increases/decreases in systolic BP or stiffness,the temporal position of diastolic BP of individual heartbeats di-gitally shifted on the APW between two temporal positions~8–12 ms apart,and the temporal position of systolic BP on the APW did not gradually shift during increases/decreases in vascular stiffness,as expected,but oscillated between constant di-gital,tri-gital,or tetra-gital temporal positions.Conclusions:Introducing new APW parameters,n-gital systolic BP fluctuations on rat APW were found.Fluctuations in n-gital were approximately constant during large changes in systolic pressure despite significant changes in augmentation index and cardiovascular stiffness,which may challenge the assumption of a gradual temporal location of systolic pressure on rat APW under these conditions.
文摘This research examines the hard-rock aquifer system within the Nagavathi River Basin(NRB)South India,by evaluating seasonal fluctuations in groundwater composition during the pre-monsoon(PRM)and post-monsoon(POM)periods.Seasonal variations significantly influence the groundwater quality,particularly fluoride(F−)concentrations,which can fluctuate due to changes in recharge,evaporation,and anthropogenic activities.This study assesses the dynamics of F−levels in PRM and POM seasons,and identifies elevated health risks using USEPA guidelines and Monte Carlo Simulations(MCS).Groundwater in the study area exhibits alkaline pH,with NaCl and Ca-Na-HCO_(3) facies increasing in the POM season due to intensified ion exchange and rock-water interactions,as indicated in Piper and Gibb’s diagrams.Correlation and dendrogram analyses indicate that F−contamination is from geogenic and anthropogenic sources.F−levels exceed the WHO limit(1.5 mg/L)in 51 PRM and 28 POM samples,affecting 371.74 km^(2) and 203.05 km^(2),respectively.Geochemical processes,including mineral weathering,cation exchange,evaporation,and dilution,are identified through CAI I&II.Health risk assessments reveal that HQ values>1 in 78%of children,73%of teens,and 68%of adults during PRM,decreasing to 45%,40%,and 38%,respectively,in POM.MCS show maximum HQ values of 5.67(PRM)and 4.73(POM)in children,with all age groups facing significant risks from fluoride ingestion.Managed Aquifer Recharge(MAR)is recommended in this study to minimize F−contamination,ensuring safe drinking water for the community.
