In order to improve the precision of super point detection and control measurement resource consumption, this paper proposes a super point detection method based on sampling and data streaming algorithms （SDSD）, and...In order to improve the precision of super point detection and control measurement resource consumption, this paper proposes a super point detection method based on sampling and data streaming algorithms （SDSD）, and proves that only sources or destinations with a lot of flows can be sampled probabilistically using the SDSD algorithm. The SDSD algorithm uses both the IP table and the flow bloom filter （BF） data structures to maintain the IP and flow information. The IP table is used to judge whether an IP address has been recorded. If the IP exists, then all its subsequent flows will be recorded into the flow BF; otherwise, the IP flow is sampled. This paper also analyzes the accuracy and memory requirements of the SDSD algorithm , and tests them using the CERNET trace. The theoretical analysis and experimental tests demonstrate that the most relative errors of the super points estimated by the SDSD algorithm are less than 5%, whereas the results of other algorithms are about 10%. Because of the BF structure, the SDSD algorithm is also better than previous algorithms in terms of memory consumption.展开更多
Distributed denial of service(DDoS)attacks are common network attacks that primarily target Internet of Things(IoT)devices.They are critical for emerging wireless services,especially for applications with limited late...Distributed denial of service(DDoS)attacks are common network attacks that primarily target Internet of Things(IoT)devices.They are critical for emerging wireless services,especially for applications with limited latency.DDoS attacks pose significant risks to entrepreneurial businesses,preventing legitimate customers from accessing their websites.These attacks require intelligent analytics before processing service requests.Distributed denial of service(DDoS)attacks exploit vulnerabilities in IoT devices by launchingmulti-point distributed attacks.These attacks generate massive traffic that overwhelms the victim’s network,disrupting normal operations.The consequences of distributed denial of service(DDoS)attacks are typically more severe in software-defined networks(SDNs)than in traditional networks.The centralised architecture of these networks can exacerbate existing vulnerabilities,as these weaknesses may not be effectively addressed in this model.The preliminary objective for detecting and mitigating distributed denial of service(DDoS)attacks in software-defined networks(SDN)is to monitor traffic patterns and identify anomalies that indicate distributed denial of service(DDoS)attacks.It implements measures to counter the effects ofDDoS attacks,and ensure network reliability and availability by leveraging the flexibility and programmability of SDN to adaptively respond to threats.The authors present a mechanism that leverages the OpenFlow and sFlow protocols to counter the threats posed by DDoS attacks.The results indicate that the proposed model effectively mitigates the negative effects of DDoS attacks in an SDN environment.展开更多
Volatile nitrosamines (VNAs) are a group of compounds classified as probable (group 2A) and possible (group 2B) carcinogens in humans. Along with certain foods and contaminated drinking water, VNAs are detected at hig...Volatile nitrosamines (VNAs) are a group of compounds classified as probable (group 2A) and possible (group 2B) carcinogens in humans. Along with certain foods and contaminated drinking water, VNAs are detected at high levels in tobacco products and in both mainstream and side-stream smoke. Our laboratory monitors six urinary VNAs—N-nitrosodimethylamine (NDMA), N-nitrosomethylethylamine (NMEA), N-nitrosodiethylamine (NDEA), N-nitrosopiperidine (NPIP), N-nitrosopyrrolidine (NPYR), and N-nitrosomorpholine (NMOR)—using isotope dilution GC-MS/ MS (QQQ) for large population studies such as the National Health and Nutrition Examination Survey (NHANES). In this paper, we report for the first time a new automated sample preparation method to more efficiently quantitate these VNAs. Automation is done using Hamilton STAR<sup>TM</sup> and Caliper Staccato<sup>TM</sup> workstations. This new automated method reduces sample preparation time from 4 hours to 2.5 hours while maintaining precision (inter-run CV < 10%) and accuracy (85% - 111%). More importantly this method increases sample throughput while maintaining a low limit of detection (<10 pg/mL) for all analytes. A streamlined sample data flow was created in parallel to the automated method, in which samples can be tracked from receiving to final LIMs output with minimal human intervention, further minimizing human error in the sample preparation process. This new automated method and the sample data flow are currently applied in bio-monitoring of VNAs in the US non-institutionalized population NHANES 2013-2014 cycle.展开更多
The imaging mass spectrometry（IMS） technology has experienced a rapid development in recent years.A new IMS technology which is based on air flow assisted ionization（AFAI） was reported.It allows for the convenient...The imaging mass spectrometry（IMS） technology has experienced a rapid development in recent years.A new IMS technology which is based on air flow assisted ionization（AFAI） was reported.It allows for the convenient pretreatment of the samples and can image a large area of sample in a single measurement with high sensitivity.The AFAI in DESI mode was used as the ion source in this paper.The new IMS method is named AFADESI-IMS.The adoption of assisted air flow makes the sample pretreatment easy and convenient.An optimization of the distance between the ion transport tube and MS orifice increases the sensitivity of the system.For data processing,a program based on MATLAB with the function of numerical analysis was developed.A theoretical imaging resolution of a few hundred microns can be achieved.The composite AFAI-IMS images of different target analytes were imaged with high sensitivity.A typical AFAI-IMS image of the whole-body section of a rat was obtained in a single analytical measurement.The ability to image a large area for relevant samples in a single measurement with high sensitivity and repeatability is a significant advantage.The method has enormous potentials in the MS imaging of large and complicated samples.展开更多
The superpoints are the sources （or the destinations） that connect with a great deal of destinations （or sources） during a measurement time interval, so detecting the superpoints in real time is very important to ...The superpoints are the sources （or the destinations） that connect with a great deal of destinations （or sources） during a measurement time interval, so detecting the superpoints in real time is very important to network security and management. Previous algorithms are not able to control the usage of the memory and to deliver the desired accuracy, so it is hard to detect the superpoints on a high speed link in real time. In this paper, we propose an adaptive sampling algorithm to detect the superpoints in real time, which uses a flow sample and hold module to reduce the detection of the non-superpoints and to improve the measurement accuracy of the superpoints. We also design a data stream structure to maintain the flow records, which compensates for the flow Hash collisions statistically. An adaptive process based on different sampling probabilities is used to maintain the recorded IP addresses in the limited memory. This algorithm is compared with the other algorithms by analyzing the real network trace data. Experiment results and mathematic analysis show that this algorithm has the advantages of both the limited memory requirement and high measurement accuracy.展开更多
基金The National Basic Research Program of China(973Program)(No.2009CB320505)the Natural Science Foundation of Jiangsu Province(No. BK2008288)+1 种基金the Excellent Young Teachers Program of Southeast University(No.4009001018)the Open Research Program of Key Laboratory of Computer Network of Guangdong Province (No. CCNL200706)
文摘In order to improve the precision of super point detection and control measurement resource consumption, this paper proposes a super point detection method based on sampling and data streaming algorithms （SDSD）, and proves that only sources or destinations with a lot of flows can be sampled probabilistically using the SDSD algorithm. The SDSD algorithm uses both the IP table and the flow bloom filter （BF） data structures to maintain the IP and flow information. The IP table is used to judge whether an IP address has been recorded. If the IP exists, then all its subsequent flows will be recorded into the flow BF; otherwise, the IP flow is sampled. This paper also analyzes the accuracy and memory requirements of the SDSD algorithm , and tests them using the CERNET trace. The theoretical analysis and experimental tests demonstrate that the most relative errors of the super points estimated by the SDSD algorithm are less than 5%, whereas the results of other algorithms are about 10%. Because of the BF structure, the SDSD algorithm is also better than previous algorithms in terms of memory consumption.
基金supported by the Deanship of Graduate Studies and Scientific Research at Qassim University for financial support(QU-APC-2025).
文摘Distributed denial of service(DDoS)attacks are common network attacks that primarily target Internet of Things(IoT)devices.They are critical for emerging wireless services,especially for applications with limited latency.DDoS attacks pose significant risks to entrepreneurial businesses,preventing legitimate customers from accessing their websites.These attacks require intelligent analytics before processing service requests.Distributed denial of service(DDoS)attacks exploit vulnerabilities in IoT devices by launchingmulti-point distributed attacks.These attacks generate massive traffic that overwhelms the victim’s network,disrupting normal operations.The consequences of distributed denial of service(DDoS)attacks are typically more severe in software-defined networks(SDNs)than in traditional networks.The centralised architecture of these networks can exacerbate existing vulnerabilities,as these weaknesses may not be effectively addressed in this model.The preliminary objective for detecting and mitigating distributed denial of service(DDoS)attacks in software-defined networks(SDN)is to monitor traffic patterns and identify anomalies that indicate distributed denial of service(DDoS)attacks.It implements measures to counter the effects ofDDoS attacks,and ensure network reliability and availability by leveraging the flexibility and programmability of SDN to adaptively respond to threats.The authors present a mechanism that leverages the OpenFlow and sFlow protocols to counter the threats posed by DDoS attacks.The results indicate that the proposed model effectively mitigates the negative effects of DDoS attacks in an SDN environment.
文摘Volatile nitrosamines (VNAs) are a group of compounds classified as probable (group 2A) and possible (group 2B) carcinogens in humans. Along with certain foods and contaminated drinking water, VNAs are detected at high levels in tobacco products and in both mainstream and side-stream smoke. Our laboratory monitors six urinary VNAs—N-nitrosodimethylamine (NDMA), N-nitrosomethylethylamine (NMEA), N-nitrosodiethylamine (NDEA), N-nitrosopiperidine (NPIP), N-nitrosopyrrolidine (NPYR), and N-nitrosomorpholine (NMOR)—using isotope dilution GC-MS/ MS (QQQ) for large population studies such as the National Health and Nutrition Examination Survey (NHANES). In this paper, we report for the first time a new automated sample preparation method to more efficiently quantitate these VNAs. Automation is done using Hamilton STAR<sup>TM</sup> and Caliper Staccato<sup>TM</sup> workstations. This new automated method reduces sample preparation time from 4 hours to 2.5 hours while maintaining precision (inter-run CV < 10%) and accuracy (85% - 111%). More importantly this method increases sample throughput while maintaining a low limit of detection (<10 pg/mL) for all analytes. A streamlined sample data flow was created in parallel to the automated method, in which samples can be tracked from receiving to final LIMs output with minimal human intervention, further minimizing human error in the sample preparation process. This new automated method and the sample data flow are currently applied in bio-monitoring of VNAs in the US non-institutionalized population NHANES 2013-2014 cycle.
基金financially supported by the National Instrumentation Program (No. 2011YQ17006702)the National Natural Science Foundation of China (No. 21027013 and No. 81102413)Fundamental Research Program of Shenzhen (No. JC201005280634A)
文摘The imaging mass spectrometry（IMS） technology has experienced a rapid development in recent years.A new IMS technology which is based on air flow assisted ionization（AFAI） was reported.It allows for the convenient pretreatment of the samples and can image a large area of sample in a single measurement with high sensitivity.The AFAI in DESI mode was used as the ion source in this paper.The new IMS method is named AFADESI-IMS.The adoption of assisted air flow makes the sample pretreatment easy and convenient.An optimization of the distance between the ion transport tube and MS orifice increases the sensitivity of the system.For data processing,a program based on MATLAB with the function of numerical analysis was developed.A theoretical imaging resolution of a few hundred microns can be achieved.The composite AFAI-IMS images of different target analytes were imaged with high sensitivity.A typical AFAI-IMS image of the whole-body section of a rat was obtained in a single analytical measurement.The ability to image a large area for relevant samples in a single measurement with high sensitivity and repeatability is a significant advantage.The method has enormous potentials in the MS imaging of large and complicated samples.
基金the National Basic Research Program of China (Grant No. 2003cb314804)
文摘The superpoints are the sources （or the destinations） that connect with a great deal of destinations （or sources） during a measurement time interval, so detecting the superpoints in real time is very important to network security and management. Previous algorithms are not able to control the usage of the memory and to deliver the desired accuracy, so it is hard to detect the superpoints on a high speed link in real time. In this paper, we propose an adaptive sampling algorithm to detect the superpoints in real time, which uses a flow sample and hold module to reduce the detection of the non-superpoints and to improve the measurement accuracy of the superpoints. We also design a data stream structure to maintain the flow records, which compensates for the flow Hash collisions statistically. An adaptive process based on different sampling probabilities is used to maintain the recorded IP addresses in the limited memory. This algorithm is compared with the other algorithms by analyzing the real network trace data. Experiment results and mathematic analysis show that this algorithm has the advantages of both the limited memory requirement and high measurement accuracy.
