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On“The Five-Step Method”in Teaching Junior English for China 被引量:1
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作者 黄金岩 《湖南工业大学学报(社会科学版)》 1997年第1期48-50,共3页
Junior English for China’ is based on the ’Five-Step’ teachingmethod: Revision, Presentation, Drilling, Practice, Consolidation. Each step has itsown particular methodology and requires the teacher to adopt a certa... Junior English for China’ is based on the ’Five-Step’ teachingmethod: Revision, Presentation, Drilling, Practice, Consolidation. Each step has itsown particular methodology and requires the teacher to adopt a certain role. Thispaper is a discussion of the "Five-Step Method". 展开更多
关键词 The five-step Method JUNIOR English for China REVISION PRESENTATION DRILLING Practice CONSOLIDATION
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Monitoring result analyses of high slope of five-step ship lock in the Three Gorges Project 被引量:5
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作者 Qixiang Fan Hongbing Zhu Jun Gen 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2015年第2期199-206,共8页
The construction of the double-lane five-step ship lock of the Three Gorges Project (TGP) wascommenced in 1994, the excavation of the ship lock was completed by the end of 1999, and the ship lockwas put in operation... The construction of the double-lane five-step ship lock of the Three Gorges Project (TGP) wascommenced in 1994, the excavation of the ship lock was completed by the end of 1999, and the ship lockwas put in operation in June 2003. The side slopes of the ship lock are characterized by great height(170 m), steepness (70 m in height of upright slope), and great length (over 7000 m in total length). Inassociation with the ship lock, the surrounding rocks in slope have a high potential to deform, withwhich the magnitude of deformation is restricted. Monitoring results show that the deformation of thefive-step ship lock high slopes of the TGP primarily occurred in excavation period, and deformationtended to be stable and convergent during operation period, suggesting the allowable ranges of deformation.At present, the slopes and lock chambers are stable, and the ship lock works well under normaloperation condition, enabling the social and economic benefits of the TGP. 2015 Institute of Rock and Soil Mechanics, Chinese Academy of Sciences. Production and hosting byElsevier B.V. All rights reserved. 展开更多
关键词 Three Gorges Project(TGP) five-step ship lock SLOPE Monitoring analysis
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pLoc_Deep-mEuk: Predict Subcellular Localization of Eukaryotic Proteins by Deep Learning 被引量:3
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作者 Yutao Shao Kuo-Chen Chou 《Natural Science》 2020年第6期400-428,共29页
<span style="font-family:Verdana;"> <p class="MsoNormal"> <span lang="EN-US" style="" color:black;"="">Recently, the life of worldwide human bei... <span style="font-family:Verdana;"> <p class="MsoNormal"> <span lang="EN-US" style="" color:black;"="">Recently, the life of worldwide human beings has been endangering by the spreading of </span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">pneu</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">- </span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">monia</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">-</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">causing virus, such as Coronavirus, COVID-19, and H1N1. To develop effective </span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">drugs against Coronavirus, knowledge of protein subcellular localization is prerequisite. In 2019, a predictor called “pLoc_bal-mEuk” was developed for identifying the subcellular localization of eukaryotic proteins. Its predicted results are significantly better than its counterparts, particularly for those proteins that may simultaneously occur or move between two or more subcellular location sites. However, more efforts are definitely needed to further improve its power since pLoc_bal-mEuk was still not trained by a “deep learning”, a very powerful technique developed recently. The present study was devoted to incorporating the “deep</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">- </span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">learning” technique and develop</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">ed</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;"> a new predictor called “pLoc_Deep-mEuk”. The global absolute true rate achieved by the new predictor is over 81% and its local accuracy is over 90%. Both are overwhelmingly superior to its counterparts. Moreover, a user-friendly web-</span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;"> </span><span style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">server for the new predictor has been well established at <a href="http://www.jci-bioinfo.cn/pLoc_Deep-mEuk/">http://www.jci-bioinfo.cn/pLoc_Deep-mEuk/</a>, by which the majority of experimental scientists can easily get their desired data.</span> </p> </span> 展开更多
关键词 CORONAVIRUS Multi-Label System Eukaryotic Proteins Deep Learning five-steps Rule PseAAC
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pLoc_Deep-mVirus: A CNN Model for Predicting Subcellular Localization of Virus Proteins by Deep Learning 被引量:3
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作者 Yutao Shao Kuo-Chen Chou 《Natural Science》 2020年第6期388-399,共12页
<p class="MsoNormal"> <span lang="EN-US" style="" color:black;"="">The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, </span>... <p class="MsoNormal"> <span lang="EN-US" style="" color:black;"="">The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, </span><span "="" style="font-variant-ligatures:normal;font-variant-caps:normal;orphans:2;text-align:start;widows:2;-webkit-text-stroke-width:0px;text-decoration-style:initial;text-decoration-color:initial;word-spacing:0px;">COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological process within a cell level and provide useful clues to develop antiviral drugs, information of virus protein subcellular localization is vitally important. In view of this, a CNN based virus protein subcellular localization predictor called “pLoc_Deep-mVirus” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 97% and its local accuracy is over 98%. Both are transcending other existing state-of-the-art predictors significantly. It has not escaped our notice that the deep-learning treatment can be used to deal with many other biological systems as well. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at <a href="http://www.jci-bioinfo.cn/pLoc_Deep-mVirus/">http://www.jci-bioinfo.cn/pLoc_Deep-mVirus/</a>.</span> </p> 展开更多
关键词 CORONAVIRUS Virus Proteins Multi-Label System Deep Learning five-steps Rule PseAAC
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pLoc_Deep-mHum: Predict Subcellular Localization of Human Proteins by Deep Learning 被引量:3
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作者 Yu-Tao Shao Xin-Xin Liu +1 位作者 Zhe Lu Kuo-Chen Chou 《Natural Science》 2020年第7期526-551,共26页
Recently, the life of human beings around the entire world has been endangering by the spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1. To develop effective drugs against Coronavirus, kno... Recently, the life of human beings around the entire world has been endangering by the spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1. To develop effective drugs against Coronavirus, knowledge of protein subcellular localization is indispensable. In 2019, a predictor called “pLoc_bal-mHum” was developed for identifying the subcellular localization of human proteins. Its predicted results are significantly better than its counterparts, particularly for those proteins that may simultaneously occur or move between two or more subcellular location sites. However, more efforts are definitely needed to further improve its power since pLoc_bal-mHum was still not trained by a “deep learning”, a very powerful technique developed recently. The present study was devoted to incorporate the “deep-learning” technique and develop a new predictor called “pLoc_Deep-mHum”. The global absolute true rate achieved by the new predictor is over 81% and its local accuracy is over 90%. Both are overwhelmingly superior to its counterparts. Moreover, a user-friendly web-server for the new predictor has been well established at http://www.jci-bioinfo.cn/pLoc_Deep-mHum/, which will become a very useful tool for fighting pandemic coronavirus and save the mankind of this planet. 展开更多
关键词 CORONAVIRUS Multi-Label System Human Proteins Deep Learning five-steps Rule PseAAC
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pLoc_Deep-mPlant: Predict Subcellular Localization of Plant Proteins by Deep Learning 被引量:2
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作者 Yu-Tao Shao Xin-Xin Liu +1 位作者 Zhe Lu Kuo-Chen Chou 《Natural Science》 2020年第5期237-247,共11页
Current coronavirus pandemic has endangered mankind life. The reported cases are increasing exponentially. Information of plant protein subcellular localization can provide useful clues to develop antiviral drugs. To ... Current coronavirus pandemic has endangered mankind life. The reported cases are increasing exponentially. Information of plant protein subcellular localization can provide useful clues to develop antiviral drugs. To cope with such a catastrophe, a CNN based plant protein subcellular localization predictor called “pLoc_Deep-mPlant” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 95% and its local accuracy is about 90%?-?100%. Both have substantially exceeded the?other existing state-of-the-art predictors. To maximize the convenience for most?experimental scientists, a user-friendly web-server for the new predictor has been established?at?http://www.jci-bioinfo.cn/pLoc_Deep-mPlant/, by which the majority of experimental?scientists can easily obtain their desired data without the need to go through the?mathematical details. 展开更多
关键词 PANDEMIC CORONAVIRUS MULTI-LABEL System Plant PROTEINS Learning at Deeper Level five-steps RULE PseAAC
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pLoc_Deep-mGneg: Predict Subcellular Localization of Gram Negative Bacterial Proteins by Deep Learning 被引量:2
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作者 Xin-Xin Liu Kuo-Chen Chou 《Advances in Bioscience and Biotechnology》 2020年第5期141-152,共12页
The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological proc... The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological process within a cell level and provide useful clues to develop antiviral drugs, information of Gram negative bacterial protein subcellular localization is vitally important. In view of this, a CNN based protein subcellular localization predictor called “pLoc_Deep-mGnet” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 98% and its local accuracy is around 94% - 100%. Both are transcending other existing state-of-the-art predictors significantly. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/pLoc_Deep-mGneg/, which will become a very useful tool for fighting pandemic coronavirus and save the mankind of this planet. 展开更多
关键词 PANDEMIC CORONAVIRUS MULTI-LABEL System GRAM Negative BACTERIAL Proteins Learning at Deeper Level five-steps Rule PseAAC
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Showcase to Illustrate How the Web-Server pLoc_Deep-mHum Is Working 被引量:2
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作者 Kuo-Chen Chou 《Advances in Bioscience and Biotechnology》 2020年第7期273-288,共16页
Recently, a very useful method called “pLoc_Deep-mHum” has been proposed for finding against the Pandemic COVID-19. Illustrated in this short report is a step-by-step guide for how to use its web-server.
关键词 CORONAVIRUS Human Proteins Multi-Label System PseAAC five-steps Rules
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pLoc_Deep-mGpos: Predict Subcellular Localization of Gram Positive Bacteria Proteins by Deep Learning 被引量:1
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作者 Zhe Lu Kuo-Chen Chou 《Journal of Biomedical Science and Engineering》 2020年第5期55-65,共11页
The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological proc... The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. In order to really understand the biological process within a cell level and provide useful clues to develop antiviral drugs, information of Gram positive bacteria protein subcellular localization is vitally important. In view of this, a CNN based protein subcellular localization predictor called “pLoc_Deep-mGpos” was developed. The predictor is particularly useful in dealing with the multi-sites systems in which some proteins may simultaneously occur in two or more different organelles that are the current focus of pharmaceutical industry. The global absolute true rate achieved by the new predictor is over 99% and its local accuracy is around 92% - 99%. Both are transcending other existing state-of-the-art predictors significantly. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/pLoc_Deep-mGpos/, which will become a very powerful tool for developing effective drugs to fight pandemic coronavirus and save the mankind of this planet. 展开更多
关键词 PANDEMIC CORONAVIRUS MULTI-LABEL System GRAM Positive PROTEINS Learning at Deeper Level five-steps Rule PseAAC
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iATC_Deep-mISF: A Multi-Label Classifier for Predicting the Classes of Anatomical Therapeutic Chemicals by Deep Learning 被引量:1
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作者 Zhe Lu Kuo-Chen Chou 《Advances in Bioscience and Biotechnology》 2020年第5期153-159,共7页
The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. To provide useful clues for developing antiviral ... The recent worldwide spreading of pneumonia-causing virus, such as Coronavirus, COVID-19, and H1N1, has been endangering the life of human beings all around the world. To provide useful clues for developing antiviral drugs, information of anatomical therapeutic chemicals is vitally important. In view of this, a CNN based predictor called “iATC_Deep-mISF” has been developed. The predictor is particularly useful in dealing with the multi-label systems in which some chemicals may occur in two or more different classes. To maximize the convenience for most experimental scientists, a user-friendly web-server for the new predictor has been established at http://www.jci-bioinfo.cn/iATC_Deep-mISF/, which will become a very powerful tool for developing effective drugs to fight pandemic coronavirus and save the mankind of this planet. 展开更多
关键词 PANDEMIC CORONAVIRUS MULTI-LABEL System ANATOMICAL THERAPEUTIC CHEMICALS Learning at Deeper Level five-steps Rule
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Showcase to Illustrate How the Web-Server pLoc_Deep-mEuk Is Working 被引量:1
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作者 Kuo-Chen Chou 《Advances in Bioscience and Biotechnology》 2020年第7期257-272,共16页
Recently, a very useful method called “pLoc_Deep-mEuk” has been proposed for finding against the Pandemic COVID-19. Illustrated in this short report is a step-by-step guide for how to use its web-server.
关键词 CORONAVIRUS Eukaryotic Proteins Multi-Label System PseAAC five-steps Rules
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高职英语书法教学改革初探 被引量:2
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作者 冯婉莎 《海外英语》 2012年第16期58-59,共2页
英语书法在英语教师教学技能中扮演着举足重轻的角色,但是在实际的教学过程中,却并未得到应有的重视。笔者根据自己的教学经验,分别从教学资源、教学手段和考核体系三个方面总结了英语书法教学中存在的问题,并探索性的提出解决方案。
关键词 高职英语 英语书法 five-step实践性教学模式 书法等级测试
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The design of double line five step ship lock of Three Gorges Project 被引量:3
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作者 Niu Xinqiang Tong Di Song Weibang 《Engineering Sciences》 EI 2011年第3期74-81,共8页
The general design and layout of the double-line five-step ship-lock,the water delivery technique for high head ship-lock,the key technical problems of fully lined ship-lock and the monitoring techniques for large-sca... The general design and layout of the double-line five-step ship-lock,the water delivery technique for high head ship-lock,the key technical problems of fully lined ship-lock and the monitoring techniques for large-scale miter gates and hoisting equipment under complicated operation conditions of Three Gorges Project (TGP) are introduced.Since the operation of ship-lock in 2003,the operation practice has proved that the design techniques are advanced,rational and reliable.The design and construction of the fully lined ship-lock promotes the development of design theory and practice of ship-lock projects,which makes the construction technology of ship-lock in the world reach a new level. 展开更多
关键词 Three Gorges Project double-line five-step design of ship-lock
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A Five-Step Food Safety Plan
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作者 LAN XINZHEN 《Beijing Review》 2007年第31期28-29,共2页
Besides the legislative and administrative efforts made by China to tackle food safety issues, a raft of measures is being introduced to punish errant producers and enforce stricter
关键词 A five-step Food Safety Plan
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