This study systematically explores the refined strategies for construction management in building decoration and renovation projects,establishing a comprehensive management system that includes process control and qua...This study systematically explores the refined strategies for construction management in building decoration and renovation projects,establishing a comprehensive management system that includes process control and quality assurance.By integrating BIM technology with intelligent tool development,the study achieved an improvement in construction quality compliance to 98.7%,a reduction in project delay rate to 1.2%,and a comprehensive cost savings of 12.7%.The“3D Standards+Five-Dimensional Monitoring”method proposed in the study effectively addresses the unique challenges of decoration projects.A total of 128 quality control points and dynamic early warning mechanisms form a replicable management paradigm,providing technical support for the industry’s implementation of the“14th Five-Year Plan for the Construction Industry.”展开更多
The effects of a fine water mist environment in a semi-confined blast chamber on the chemical and thermodynamic processes following detonation of a 20 g PE4 explosive charge have been investigated.The effects were qua...The effects of a fine water mist environment in a semi-confined blast chamber on the chemical and thermodynamic processes following detonation of a 20 g PE4 explosive charge have been investigated.The effects were quantified by the analysis of pressure profiles recorded where several parameters including arrival time of the shock at the sensors, peak overpressures, specific impulse of the positive phase, period of the negative phase and the specific impulse of the multiple reflections were quantified.The effect of the fine water mist on the arrival time, peak pressures and the specific impulse of the positive phase agrees with previous findings in literature. In this paper, the focus is on the implications of the fine water mist on the negative phase and the impulse of multiple pressure reflections. The period of the negative phase was found to have increased by 40% and with higher negative peak pressure in the mist condition compared to the atmospheric condition. The activities of the multiple pressure reflections were found to have decreased considerably, both in number and in amplitude leading to lower impulses(by about 60%) for the water mist conditions.展开更多
Ⅰ. Exchange Rates Excharge rates are the rates at which currency conversion takes place. They themselves tell us nothing about the relative strength of the currencies involved or economics behind them, It simply refl...Ⅰ. Exchange Rates Excharge rates are the rates at which currency conversion takes place. They themselves tell us nothing about the relative strength of the currencies involved or economics behind them, It simply reflects the difference between the denominations into which the two countries have chosen to divide their respective currencies. A currency is considered externally weak if the government is having difficulty maintaining the predetermined exchange rates under展开更多
The advanced hot-rolled transformation induced plasticity （TRIP） steel with high tensile strength of 775 MPa, high elongation of 29% and low ductile-brittle transmission temperature less than -80℃ has been develope...The advanced hot-rolled transformation induced plasticity （TRIP） steel with high tensile strength of 775 MPa, high elongation of 29% and low ductile-brittle transmission temperature less than -80℃ has been developed in laboratory based on the common silicon and manganese chemical composition. The experimental results showed that the microstructures were featured with ultra fine grain size less than 5μm, appropriate retained austenite volume fraction around 11.8% and purified ferrite grain, which may result in well balanced mechanical properties for the steel.展开更多
Refined management has become an inevitable trend in the development stage of social economy. Construction engineering enterprises gradually realize the importance of creating refined management mode and are committed...Refined management has become an inevitable trend in the development stage of social economy. Construction engineering enterprises gradually realize the importance of creating refined management mode and are committed to achieving the goal of refined management in the construction stage to ensure the effective implementation of quality management. In view of this, this paper discusses the application of refined management in construction project management.展开更多
This paper first analyzes the necessity of refined management of highway engineering construction technology, and then analyzes the measures of refined management of highway engineering construction technology from fi...This paper first analyzes the necessity of refined management of highway engineering construction technology, and then analyzes the measures of refined management of highway engineering construction technology from five aspects of system, progress, cost, quality and safety, combined with specific highway engineering projects, so as to provide reference for similar projects.展开更多
Objective: to determine the clinical effects of several cases of severe pneumonia in children. Methods: 90 children with severe pneumonia from February 2020 to August 2020 were selected. The control group was given ro...Objective: to determine the clinical effects of several cases of severe pneumonia in children. Methods: 90 children with severe pneumonia from February 2020 to August 2020 were selected. The control group was given routine care, and the experimental group was given essence care. The results showed that when the lung function indexes were consistent with the control group, the lung function of the education group was good, which was consistent with the control group (P < 0.05). The use of the most complex natural regimen in the treatment of children with severe pneumonia could improve their clinical symptoms, natural risk and utilization rate.展开更多
At present, China's medical and health undertakings have been greatly developed, which also leads to increasingly fierce competition among medical institutions. The information management mechanism and related tec...At present, China's medical and health undertakings have been greatly developed, which also leads to increasingly fierce competition among medical institutions. The information management mechanism and related technologies in the medical system are becoming more and more mature, and the total amount of consumables in the hospital is gradually increasing. Therefore, it is very important to manage the medical equipment consumables in the hospital well. Based on this, this paper discusses the fine management of medical equipment consumables in detail. First of all, this paper summarized the problems existing in the traditional financial management and control of the medical system, and then put forward specific solutions for the shortcomings of the summary, in order to improve the quality of the refined management of medical device consumables in hospitals.展开更多
Fang Chuxiong’s works combine the meticulousness of fine brushwork with the elegance of freehand brushstrokes,making him a distinct figure in the contemporary Chinese art circle.Fang Chuxiong is a representative figu...Fang Chuxiong’s works combine the meticulousness of fine brushwork with the elegance of freehand brushstrokes,making him a distinct figure in the contemporary Chinese art circle.Fang Chuxiong is a representative figure in the field of contemporary Chinese flower-and-bird painting.His artwork masterfully integrates the elements of nature,the charm of living creatures,the subtleties of brushwork,and the vitality of color,exhibiting refined taste and a vibrant style.展开更多
China has long been criticized for media censorship and a recently discussed draft law on handling sudden events, which would see news media fined for reporting on emergencies without government approval, has again pu...China has long been criticized for media censorship and a recently discussed draft law on handling sudden events, which would see news media fined for reporting on emergencies without government approval, has again put China at the center of wide-ranging criticism. The draft law was submitted to the Standing Committee of the展开更多
It is common to see pedestrians crossing in the middle of a street or ignoring a traffic light, deliberately or unconsciously, especially in small and medium-sized cities. Two decades ago, there were few cars, and the...It is common to see pedestrians crossing in the middle of a street or ignoring a traffic light, deliberately or unconsciously, especially in small and medium-sized cities. Two decades ago, there were few cars, and the traffic laws were inadequate. Therefore, people developed the mind-set that they will not be punished for this common behavior and that there is nothing wrong in jaywalking. However, nowadays, with the展开更多
Holography can provide the desired wavefront phase and/or amplitude for imaging,particle manipulation,bacteria trapping,and cell patterning in optics and acoustics.However,previous work on acoustic holography is mostl...Holography can provide the desired wavefront phase and/or amplitude for imaging,particle manipulation,bacteria trapping,and cell patterning in optics and acoustics.However,previous work on acoustic holography is mostly based on local design optimization,either using active control of the sound source or relying on the structural design to provide the desired wavefront.Achieving precise control over the acoustic field remains a significant challenge.Here,we realize refined single-plane symmetric binary amplitude,asymmetric intensity gradient amplitude,and bi-objective hologram through the non-local holographic imaging theory that considers the acoustic coupling of structural units in detail.By taking into account the self-radiation and mutual radiation between many small units on a plate of well-designed thickness,as well as the transmission through the plate's apertures,we can effectively regulate the sound field behind the plate.We demonstrate the effectiveness of our approach through numerical simulations and experiments,showcasing a circle,a black hole,and a bi-objective with a circle and a square hologram.Notably,the acoustic black hole hologram precisely reconstructs the intensity gradient distribution at two bright spots.This non-local holographic imaging theory is valuable for the fine-intensity regulation of the sound field and is expected to be applied in ultrasound diagnosis and treatment,medical imaging,and other fields.展开更多
Pancreatic cysts are mostly incidental findings on computed tomography or magnetic resonance imaging scans,with few patients presenting with abdominal pain or other symptoms.The accurate diagnosis of cysts is importan...Pancreatic cysts are mostly incidental findings on computed tomography or magnetic resonance imaging scans,with few patients presenting with abdominal pain or other symptoms.The accurate diagnosis of cysts is important as management depends on the type(neoplastic or non-neoplastic).Cross-sectional imaging is fast being replaced with endoscopic ultrasound(EUS)and various techniques based on that such as EUS-guided fine needle aspiration,EUS-guided needle confocal laser endomicroscopy,EUS-through-the-needle biopsy,and contrast-enhanced EUS.Clinical studies have reported varying diagnostic and adverse event rates with these modalities.In addition,American,European,and Kyoto guidelines for the diagnosis and management of pancreatic cysts have provided different recommendations.In this editorial,we elaborate on the clinical guidelines,recent studies,and comparison of different endoscopic methods for the diagnosis of pancreatic cysts.展开更多
Powdery mildew negatively impacts wheat yield and quality.Emmer wheat(Triticum dicoccum),an ancestral species of common wheat,is a gene donor for wheat improvement.Cultivated emmer accession H1-707 exhibited all-stage...Powdery mildew negatively impacts wheat yield and quality.Emmer wheat(Triticum dicoccum),an ancestral species of common wheat,is a gene donor for wheat improvement.Cultivated emmer accession H1-707 exhibited all-stage resistance to powdery mildew over consecutive years.Genetic analysis of H1-707 at the seedling stage revealed a dominant monogenic inheritance pattern,and the underlying gene was designated Pm71.By employing bulked segregant exome sequencing(BSE-Seq)and using 2000 F2:3 families,Pm71 was fine mapped to a 336-kb interval on chromosome arm 6AS by referencing to the durum cv.Svevo RefSeq 1.0.Collinearity analysis revealed high homology in the candidate interval between Svevo and six Triticum species.Among six high-confidence genes annotated within this interval,TRITD6Av1G005050 encoding a GDSL esterase/lipase was identified as a key candidate for Pm71.展开更多
The introduction of wireless capsule endoscopy has brought a revolutionary change in the diagnostic procedures for gastrointestinal disorders.Biopsy,an essential procedure for disease diagnosis,has been integrated int...The introduction of wireless capsule endoscopy has brought a revolutionary change in the diagnostic procedures for gastrointestinal disorders.Biopsy,an essential procedure for disease diagnosis,has been integrated into robotic capsule endoscopy to augment diagnostic capabilities.In this study,we propose a magnetically driven biopsy robot based on a Kresling origami.Considering the bistable properties of Krelsing origami and the elasticity of the creases,a foldable structure of the robot with constant force characteristics is designed.The folding motion of the structure is used to deploy the needle into the target tissue.The robot is capable of performing rolling motion under the control of an external magnetic drive system,and a fine needle biopsy technique is used to collect deep tissue samples.We also conduct in vitro rolling experiments and sampling experiments on apple tissues and pork tissues,which verify the performance of the robot.展开更多
A new adsorbent was successfully prepared by hydrothermal treatment and chemical activation through coal gasification fine slag(CGFS)and blue algae(BA)as raw materials and used for CO_(2)capture.The CO_(2)chemisorptio...A new adsorbent was successfully prepared by hydrothermal treatment and chemical activation through coal gasification fine slag(CGFS)and blue algae(BA)as raw materials and used for CO_(2)capture.The CO_(2)chemisorption capacity of the adsorbent was further enhanced by taking advantage of the nitrogenous bases contained in the BA.In the hydrothermal process,the addition of BA significantly increased the content of pyrrole nitrogen in the adsorbent.In the activation process,pyrrole nitrogen gradually changed into pyridine nitrogen and graphite nitrogen.Increased BA addition result in a higher specific surface area and microporosity of the adsorbent.The CO_(2)adsorption performance test proved that the CGFS-50%-CA sample has the strongest CO_(2)adsorption capacity at low temperature,up to 15.59 cm^(3)/g,which is mainly through physical adsorption,and the CGFS-10%-CA sample has the strongest CO_(2)adsorption capacity at high temperature,up to 7.31 cm^(3)/g,which is mainly through chemical adsorption.CO_(2)uptake of the CGFS-10%-CA sample was well maintained after 10 cycles,with regeneration efficiencies above 99%.The results indicate that the novel adsorbents with coexistence of physical and chemical adsorption have great potential for CO_(2)adsorption applications.展开更多
Hanyu Xu 1,Xuedan Song 1,*,Qing Zhang 1,Chang Yu 1,Jieshan Qiu 1,2,*1 Liaoning Key Lab for Energy Materials and Chemical Engineering,State Key Laboratory of Fine Chemicals,School of Chemical Engineering,Dalian Univers...Hanyu Xu 1,Xuedan Song 1,*,Qing Zhang 1,Chang Yu 1,Jieshan Qiu 1,2,*1 Liaoning Key Lab for Energy Materials and Chemical Engineering,State Key Laboratory of Fine Chemicals,School of Chemical Engineering,Dalian University of Technology,Dalian 116024,Liaoning Province,China.展开更多
Increasing evidence suggests that fine roots are particularly sensitive to environmental changes,making them essential in responding and adapting forest ecosystems to climate change.However,we still lack a fundamental...Increasing evidence suggests that fine roots are particularly sensitive to environmental changes,making them essential in responding and adapting forest ecosystems to climate change.However,we still lack a fundamental understanding of the underlying mechanisms that control fine root plasticity.The objective of this study was to determine the influence of soil moisture changes on fine root dynamics and morphology of European beech(Fagus sylvatica L.).We conducted a 30-month study of fine root traits,i.e.,fine root biomass(FRB),productivity,mortality,turnover,specific root length(SRL),specific root area(SRA),and root tip frequency(RTF),along a soil moisture gradient from dry,intermediate,and wet conditions in a near-natural mature beech forest.Sequential root coring with accompanying soil measurements was carried out at three study sites reflecting the gradient in soil water availability.For most fine root traits,we found significant differences between the upper 10 cm and lower soil depths.FRB showed significant differences between study sites,with the lowest FRB at the dry site.However,productivity,turnover,SRL,SRA,and RTF showed no significant differences between sites,but a high variability between seasons,suggesting an adaptation to short-term fluctuations but not to long-term gradients in soil water content(SWC).Linear mixed models revealed that decreasing SWC led to a significant increase in SRL,SRA,and RTF(standardized coefficients:-1.0±0.46,-1.1±0.46,and-1.1±0.43,respectively).Our observations indicate an adaptation strategy of beech to low availability of soil water and drought by forming thin absorptive roots and by maintaining a high seasonal plasticity to tolerate fluctuations in soil moisture.By highlighting the belowground morphological adaptations of mature forests to low soil water availability,our results provide novel insights into the structure and dynamics of forest ecosystem adaptations to climate change.展开更多
Fine particulate matter(particulate matter with a diameter of 2.5μm or less;PM2.5)causes millions of premature deaths globally1,but not all particles are equally harmful2-4.Current air-pollution control strategies,pr...Fine particulate matter(particulate matter with a diameter of 2.5μm or less;PM2.5)causes millions of premature deaths globally1,but not all particles are equally harmful2-4.Current air-pollution control strategies,prioritizing PM2.5 mass reduction,have provided considerable health benefits but further refinements based on differences in the toxicity of various emission sources may provide greater benefits5-7.Here we integrated field measurements with air-quality modelling to assess the unequal toxicities of PM2.5 from various anthropogenic sources.展开更多
BACKGROUND Liver biopsy is an important diagnostic tool to investigate patients with suspected liver disease.The efficacy and safety of endoscopic ultrasound-guided liver biopsy(EUS-LB)as a method for liver tissue acq...BACKGROUND Liver biopsy is an important diagnostic tool to investigate patients with suspected liver disease.The efficacy and safety of endoscopic ultrasound-guided liver biopsy(EUS-LB)as a method for liver tissue acquisition remain uncertain.AIM To study the diagnostic yield and safety of EUS-LB in patients with suspected parenchymal liver disease.METHODS This is a retrospective observational cohort study of patients undergoing EUS-LB in 2 tertiary-care centers in Kuwait in the period between January 2022-June 2025.The primary outcome was sample adequacy,while secondary outcomes included histological quality of the specimen and adverse events.Predictors of increased diagnostic adequacy and specimen quality were explored.RESULTS A total of 50 patients[mean age 43.9(15.5)years,40%males]were included.The left liver lobe was targeted for biopsy in most patients(96%),and 19-gauge fine needle aspiration(FNA)was used in most cases(52%).The median number of passes performed was 3(range 2-5),and the heparin-wet suction technique was used in 40%of patients.The overall diagnostic adequacy of EUS-LB was 86%,with no significant difference between 19-gauge FNA and 19-gauge fine needle biopsy(FNB)needles.Fulfillment of the European Association for the Study of Liver(EASL)and the American Association for the Study of Liver Diseases criteria was achieved in 54%and 34%,respectively,with a significantly higher number of patients fulfilling these criteria when FNB needle was used compared to FNA needle(83.3%vs 26.9%,P<0.0001)and(62.5%vs 7.7%,P<0.0001),respectively.Only 1 patient(2.0%)developed adverse post-procedure events,namely bleeding requiring transfusion.Multivariate regression analysis did not identify any factor that increased diagnostic adequacy;however,the use of FNB needles and wet heparin suction methods were associated with significantly increased odds of fulfilling EASL criteria,while performing more than 2 passes reduced the quality of the specimen.CONCLUSION EUS-LB is an effective and safe method for obtaining liver biopsy in patients with suspected parenchymal liver disease.EUS-LB demonstrated a favorable safety profile in our cohort,although larger prospective studies are required to validate bleeding risk.The use of 19-gauge FNB needles,wet-heparin suction technique,and performing≤2 passes is associated with improved quality of the specimen obtained without increasing the risk of adverse events.展开更多
文摘This study systematically explores the refined strategies for construction management in building decoration and renovation projects,establishing a comprehensive management system that includes process control and quality assurance.By integrating BIM technology with intelligent tool development,the study achieved an improvement in construction quality compliance to 98.7%,a reduction in project delay rate to 1.2%,and a comprehensive cost savings of 12.7%.The“3D Standards+Five-Dimensional Monitoring”method proposed in the study effectively addresses the unique challenges of decoration projects.A total of 128 quality control points and dynamic early warning mechanisms form a replicable management paradigm,providing technical support for the industry’s implementation of the“14th Five-Year Plan for the Construction Industry.”
文摘The effects of a fine water mist environment in a semi-confined blast chamber on the chemical and thermodynamic processes following detonation of a 20 g PE4 explosive charge have been investigated.The effects were quantified by the analysis of pressure profiles recorded where several parameters including arrival time of the shock at the sensors, peak overpressures, specific impulse of the positive phase, period of the negative phase and the specific impulse of the multiple reflections were quantified.The effect of the fine water mist on the arrival time, peak pressures and the specific impulse of the positive phase agrees with previous findings in literature. In this paper, the focus is on the implications of the fine water mist on the negative phase and the impulse of multiple pressure reflections. The period of the negative phase was found to have increased by 40% and with higher negative peak pressure in the mist condition compared to the atmospheric condition. The activities of the multiple pressure reflections were found to have decreased considerably, both in number and in amplitude leading to lower impulses(by about 60%) for the water mist conditions.
文摘Ⅰ. Exchange Rates Excharge rates are the rates at which currency conversion takes place. They themselves tell us nothing about the relative strength of the currencies involved or economics behind them, It simply reflects the difference between the denominations into which the two countries have chosen to divide their respective currencies. A currency is considered externally weak if the government is having difficulty maintaining the predetermined exchange rates under
文摘The advanced hot-rolled transformation induced plasticity （TRIP） steel with high tensile strength of 775 MPa, high elongation of 29% and low ductile-brittle transmission temperature less than -80℃ has been developed in laboratory based on the common silicon and manganese chemical composition. The experimental results showed that the microstructures were featured with ultra fine grain size less than 5μm, appropriate retained austenite volume fraction around 11.8% and purified ferrite grain, which may result in well balanced mechanical properties for the steel.
文摘Refined management has become an inevitable trend in the development stage of social economy. Construction engineering enterprises gradually realize the importance of creating refined management mode and are committed to achieving the goal of refined management in the construction stage to ensure the effective implementation of quality management. In view of this, this paper discusses the application of refined management in construction project management.
文摘This paper first analyzes the necessity of refined management of highway engineering construction technology, and then analyzes the measures of refined management of highway engineering construction technology from five aspects of system, progress, cost, quality and safety, combined with specific highway engineering projects, so as to provide reference for similar projects.
文摘Objective: to determine the clinical effects of several cases of severe pneumonia in children. Methods: 90 children with severe pneumonia from February 2020 to August 2020 were selected. The control group was given routine care, and the experimental group was given essence care. The results showed that when the lung function indexes were consistent with the control group, the lung function of the education group was good, which was consistent with the control group (P < 0.05). The use of the most complex natural regimen in the treatment of children with severe pneumonia could improve their clinical symptoms, natural risk and utilization rate.
文摘At present, China's medical and health undertakings have been greatly developed, which also leads to increasingly fierce competition among medical institutions. The information management mechanism and related technologies in the medical system are becoming more and more mature, and the total amount of consumables in the hospital is gradually increasing. Therefore, it is very important to manage the medical equipment consumables in the hospital well. Based on this, this paper discusses the fine management of medical equipment consumables in detail. First of all, this paper summarized the problems existing in the traditional financial management and control of the medical system, and then put forward specific solutions for the shortcomings of the summary, in order to improve the quality of the refined management of medical device consumables in hospitals.
文摘Fang Chuxiong’s works combine the meticulousness of fine brushwork with the elegance of freehand brushstrokes,making him a distinct figure in the contemporary Chinese art circle.Fang Chuxiong is a representative figure in the field of contemporary Chinese flower-and-bird painting.His artwork masterfully integrates the elements of nature,the charm of living creatures,the subtleties of brushwork,and the vitality of color,exhibiting refined taste and a vibrant style.
文摘China has long been criticized for media censorship and a recently discussed draft law on handling sudden events, which would see news media fined for reporting on emergencies without government approval, has again put China at the center of wide-ranging criticism. The draft law was submitted to the Standing Committee of the
文摘It is common to see pedestrians crossing in the middle of a street or ignoring a traffic light, deliberately or unconsciously, especially in small and medium-sized cities. Two decades ago, there were few cars, and the traffic laws were inadequate. Therefore, people developed the mind-set that they will not be punished for this common behavior and that there is nothing wrong in jaywalking. However, nowadays, with the
基金supported by the National Key R&D Program of China(Grant Nos.2020YFA0211400,and 2020YFA0211402)the National Natural Science Foundation of China(Grant Nos.42074179,11774266,92263208,and 12074286)the Shanghai Science and Technology Committee(Grant No.21JC1405600)。
文摘Holography can provide the desired wavefront phase and/or amplitude for imaging,particle manipulation,bacteria trapping,and cell patterning in optics and acoustics.However,previous work on acoustic holography is mostly based on local design optimization,either using active control of the sound source or relying on the structural design to provide the desired wavefront.Achieving precise control over the acoustic field remains a significant challenge.Here,we realize refined single-plane symmetric binary amplitude,asymmetric intensity gradient amplitude,and bi-objective hologram through the non-local holographic imaging theory that considers the acoustic coupling of structural units in detail.By taking into account the self-radiation and mutual radiation between many small units on a plate of well-designed thickness,as well as the transmission through the plate's apertures,we can effectively regulate the sound field behind the plate.We demonstrate the effectiveness of our approach through numerical simulations and experiments,showcasing a circle,a black hole,and a bi-objective with a circle and a square hologram.Notably,the acoustic black hole hologram precisely reconstructs the intensity gradient distribution at two bright spots.This non-local holographic imaging theory is valuable for the fine-intensity regulation of the sound field and is expected to be applied in ultrasound diagnosis and treatment,medical imaging,and other fields.
文摘Pancreatic cysts are mostly incidental findings on computed tomography or magnetic resonance imaging scans,with few patients presenting with abdominal pain or other symptoms.The accurate diagnosis of cysts is important as management depends on the type(neoplastic or non-neoplastic).Cross-sectional imaging is fast being replaced with endoscopic ultrasound(EUS)and various techniques based on that such as EUS-guided fine needle aspiration,EUS-guided needle confocal laser endomicroscopy,EUS-through-the-needle biopsy,and contrast-enhanced EUS.Clinical studies have reported varying diagnostic and adverse event rates with these modalities.In addition,American,European,and Kyoto guidelines for the diagnosis and management of pancreatic cysts have provided different recommendations.In this editorial,we elaborate on the clinical guidelines,recent studies,and comparison of different endoscopic methods for the diagnosis of pancreatic cysts.
基金financially supported by National Natural Science Foundation of China(32301800,32301923 and 32072053)Wheat Industrial Technology System of Shandong Province(SDAIT-01-01)Key Research and Development Project of Shandong Province(2022LZG002-4,2023LZGC009-4-4).
文摘Powdery mildew negatively impacts wheat yield and quality.Emmer wheat(Triticum dicoccum),an ancestral species of common wheat,is a gene donor for wheat improvement.Cultivated emmer accession H1-707 exhibited all-stage resistance to powdery mildew over consecutive years.Genetic analysis of H1-707 at the seedling stage revealed a dominant monogenic inheritance pattern,and the underlying gene was designated Pm71.By employing bulked segregant exome sequencing(BSE-Seq)and using 2000 F2:3 families,Pm71 was fine mapped to a 336-kb interval on chromosome arm 6AS by referencing to the durum cv.Svevo RefSeq 1.0.Collinearity analysis revealed high homology in the candidate interval between Svevo and six Triticum species.Among six high-confidence genes annotated within this interval,TRITD6Av1G005050 encoding a GDSL esterase/lipase was identified as a key candidate for Pm71.
基金supported by the National Natural Science Foundation of China(Grant Nos.51805047 and 52175003)the Outstanding Youth Program of Hunan Education Department(Grant No.23B0335)the Natural Science Foundation of Hunan Province(Grant Nos.2023JJ30021 and 2023JJ50077).
文摘The introduction of wireless capsule endoscopy has brought a revolutionary change in the diagnostic procedures for gastrointestinal disorders.Biopsy,an essential procedure for disease diagnosis,has been integrated into robotic capsule endoscopy to augment diagnostic capabilities.In this study,we propose a magnetically driven biopsy robot based on a Kresling origami.Considering the bistable properties of Krelsing origami and the elasticity of the creases,a foldable structure of the robot with constant force characteristics is designed.The folding motion of the structure is used to deploy the needle into the target tissue.The robot is capable of performing rolling motion under the control of an external magnetic drive system,and a fine needle biopsy technique is used to collect deep tissue samples.We also conduct in vitro rolling experiments and sampling experiments on apple tissues and pork tissues,which verify the performance of the robot.
基金supported by the National Natural Science Foundation of China(22168032)the National Key Research and Development Program of China(2023YFC3904302,2023YFB4103500)the Key Projects of Ning Dong Energy and Chemical Industry Base(2023NDKJXMLX022).
文摘A new adsorbent was successfully prepared by hydrothermal treatment and chemical activation through coal gasification fine slag(CGFS)and blue algae(BA)as raw materials and used for CO_(2)capture.The CO_(2)chemisorption capacity of the adsorbent was further enhanced by taking advantage of the nitrogenous bases contained in the BA.In the hydrothermal process,the addition of BA significantly increased the content of pyrrole nitrogen in the adsorbent.In the activation process,pyrrole nitrogen gradually changed into pyridine nitrogen and graphite nitrogen.Increased BA addition result in a higher specific surface area and microporosity of the adsorbent.The CO_(2)adsorption performance test proved that the CGFS-50%-CA sample has the strongest CO_(2)adsorption capacity at low temperature,up to 15.59 cm^(3)/g,which is mainly through physical adsorption,and the CGFS-10%-CA sample has the strongest CO_(2)adsorption capacity at high temperature,up to 7.31 cm^(3)/g,which is mainly through chemical adsorption.CO_(2)uptake of the CGFS-10%-CA sample was well maintained after 10 cycles,with regeneration efficiencies above 99%.The results indicate that the novel adsorbents with coexistence of physical and chemical adsorption have great potential for CO_(2)adsorption applications.
文摘Hanyu Xu 1,Xuedan Song 1,*,Qing Zhang 1,Chang Yu 1,Jieshan Qiu 1,2,*1 Liaoning Key Lab for Energy Materials and Chemical Engineering,State Key Laboratory of Fine Chemicals,School of Chemical Engineering,Dalian University of Technology,Dalian 116024,Liaoning Province,China.
基金supported by the Federal Ministry of Food and Agriculture (BMEL)the Federal Ministry for the Environment,Nature Conservation,Nuclear Safety and Consumer Protection (BMUV) through the Fachagentur Nachwachsende Rohstoffe e. V.(FNR)(grant no. 2218 WK53X4)
文摘Increasing evidence suggests that fine roots are particularly sensitive to environmental changes,making them essential in responding and adapting forest ecosystems to climate change.However,we still lack a fundamental understanding of the underlying mechanisms that control fine root plasticity.The objective of this study was to determine the influence of soil moisture changes on fine root dynamics and morphology of European beech(Fagus sylvatica L.).We conducted a 30-month study of fine root traits,i.e.,fine root biomass(FRB),productivity,mortality,turnover,specific root length(SRL),specific root area(SRA),and root tip frequency(RTF),along a soil moisture gradient from dry,intermediate,and wet conditions in a near-natural mature beech forest.Sequential root coring with accompanying soil measurements was carried out at three study sites reflecting the gradient in soil water availability.For most fine root traits,we found significant differences between the upper 10 cm and lower soil depths.FRB showed significant differences between study sites,with the lowest FRB at the dry site.However,productivity,turnover,SRL,SRA,and RTF showed no significant differences between sites,but a high variability between seasons,suggesting an adaptation to short-term fluctuations but not to long-term gradients in soil water content(SWC).Linear mixed models revealed that decreasing SWC led to a significant increase in SRL,SRA,and RTF(standardized coefficients:-1.0±0.46,-1.1±0.46,and-1.1±0.43,respectively).Our observations indicate an adaptation strategy of beech to low availability of soil water and drought by forming thin absorptive roots and by maintaining a high seasonal plasticity to tolerate fluctuations in soil moisture.By highlighting the belowground morphological adaptations of mature forests to low soil water availability,our results provide novel insights into the structure and dynamics of forest ecosystem adaptations to climate change.
文摘Fine particulate matter(particulate matter with a diameter of 2.5μm or less;PM2.5)causes millions of premature deaths globally1,but not all particles are equally harmful2-4.Current air-pollution control strategies,prioritizing PM2.5 mass reduction,have provided considerable health benefits but further refinements based on differences in the toxicity of various emission sources may provide greater benefits5-7.Here we integrated field measurements with air-quality modelling to assess the unequal toxicities of PM2.5 from various anthropogenic sources.
文摘BACKGROUND Liver biopsy is an important diagnostic tool to investigate patients with suspected liver disease.The efficacy and safety of endoscopic ultrasound-guided liver biopsy(EUS-LB)as a method for liver tissue acquisition remain uncertain.AIM To study the diagnostic yield and safety of EUS-LB in patients with suspected parenchymal liver disease.METHODS This is a retrospective observational cohort study of patients undergoing EUS-LB in 2 tertiary-care centers in Kuwait in the period between January 2022-June 2025.The primary outcome was sample adequacy,while secondary outcomes included histological quality of the specimen and adverse events.Predictors of increased diagnostic adequacy and specimen quality were explored.RESULTS A total of 50 patients[mean age 43.9(15.5)years,40%males]were included.The left liver lobe was targeted for biopsy in most patients(96%),and 19-gauge fine needle aspiration(FNA)was used in most cases(52%).The median number of passes performed was 3(range 2-5),and the heparin-wet suction technique was used in 40%of patients.The overall diagnostic adequacy of EUS-LB was 86%,with no significant difference between 19-gauge FNA and 19-gauge fine needle biopsy(FNB)needles.Fulfillment of the European Association for the Study of Liver(EASL)and the American Association for the Study of Liver Diseases criteria was achieved in 54%and 34%,respectively,with a significantly higher number of patients fulfilling these criteria when FNB needle was used compared to FNA needle(83.3%vs 26.9%,P<0.0001)and(62.5%vs 7.7%,P<0.0001),respectively.Only 1 patient(2.0%)developed adverse post-procedure events,namely bleeding requiring transfusion.Multivariate regression analysis did not identify any factor that increased diagnostic adequacy;however,the use of FNB needles and wet heparin suction methods were associated with significantly increased odds of fulfilling EASL criteria,while performing more than 2 passes reduced the quality of the specimen.CONCLUSION EUS-LB is an effective and safe method for obtaining liver biopsy in patients with suspected parenchymal liver disease.EUS-LB demonstrated a favorable safety profile in our cohort,although larger prospective studies are required to validate bleeding risk.The use of 19-gauge FNB needles,wet-heparin suction technique,and performing≤2 passes is associated with improved quality of the specimen obtained without increasing the risk of adverse events.
