In order to optimize the reaming process of the type IV composite hydrogen storage cylinder,the netting theory was employed for the design of stacking sequences,and the thickness in the head section was predicted.A fi...In order to optimize the reaming process of the type IV composite hydrogen storage cylinder,the netting theory was employed for the design of stacking sequences,and the thickness in the head section was predicted.A finite element model of the plastic-lined composite hydrogen storage cylinder,designed to withstand a working pressure of 70.0 MPa,was established by using the wound composite modeler(WCM)in the Abaqus software to analyze the forces acting on the winding layer.The Hashin failure criterion was utilized as the standard for assessing composite failure,and a progressive failure analysis of the cylinder was conducted to predict both the bursting pressure and the failure location of the composite hydrogen storage cylinder.The results indicate that the reaming process can effectively reduce the maximum filament winding thickness in the head section and promote a more uniform transition.At the bursting pressure,the stress within the head liner decreases,thereby enhancing the ultimate bearing capacity of the cylinder.A control system for a four-axis winding machine was designed by utilizing an industrial computer and a programmable multi-axis controller(PMAC).The winding line pattern is designed and the G-code trajectory is generated by the industrial computer.The numerical control system,composed of the PMAC and servo motor,executes the four-axis interpolation motion.展开更多
With the increasing accumulation of plastic pollutants in various environments,research on microorganisms(including bacteria,fungi,and algae)with plastic degradation capabilities has gained significant attention.Howev...With the increasing accumulation of plastic pollutants in various environments,research on microorganisms(including bacteria,fungi,and algae)with plastic degradation capabilities has gained significant attention.However,only a limited number of microbial plastic-degrading enzymes have been identified to date.This highlights that the degradation mechanisms employed by many plastic-degrading microorganisms,particularly filamentous fungi,remain insufficiently explored.In this study,we utilized a versatile fungal plasmid(pCT74)to express green fluorescent protein(GFP)in a marine-derived fungus Alternaria alternata strain FB1 with plastic degradation capabilities.Upon evaluating the degradation effect of polyester-type polyurethane(PU)film,we observed that different transformants exhibited three kinds of activities(the same,reduced,or enhanced degradation capability)compared to the FB1 wild-type strain.Further analysis of the plasmid fragment insertion sites in different transformants revealed that pCT74 integrates randomly into the genome of the host fungus.Notably,a direct correlation was found between the plasmid insertion site and the degradation capability of the corresponding transformant.Our findings not only redefine the potential applications of plasmid pCT74 in filamentous fungi but also show a novel research approach to identifying key enzymes involved in plastic degradation by fungi.展开更多
Unmanned combat aerial vehicles require lightweight,stealth-capable exhaust systems.However,traditional metallic nozzles increase radar detectability and reduce range,while advanced composites offer high performance b...Unmanned combat aerial vehicles require lightweight,stealth-capable exhaust systems.However,traditional metallic nozzles increase radar detectability and reduce range,while advanced composites offer high performance but are expensive.Therefore,to improve the operational range and survivability of unmanned combat aerial vehicles,a lightweight,high-temperature-resistant,oxidation-resistant,and low-observable composite exhaust nozzle is developed to replace conventional metallic straight-type nozzles.The nozzle features a double serpentine shape to reduce radar and infrared signatures and is manufactured as a monolithic structure using the filament winding process,accommodating the complex geometry and large size(length:1.8 m,width:0.8 m).The exhaust nozzle consists of a ceramic matrix composite made of silicon carbide fibers and a silicon oxycarbide matrix,which absorbs and scatters radio frequency signals while withstanding prolonged exposure to high-temperature(700℃)oxidizing environments typical of engine exhaust gases.The polysiloxane resin used to produce the silicon oxycarbide matrix poses significant challenges owing to its low tackiness and high viscosity variations depending on the presence of nanoparticles,making filament winding difficult.These challenges are addressed by optimizing resin viscosity and winding pattern design.As a result,the tensile strength of the composite specimens fabricated with the optimized viscosity increases by 228.03% before pyrolysis and 97.68%after pyrolysis,compared with that of the non-optimized specimens.In addition,the density and tensile strength of the composite processed via three cycles of polymer infiltration and pyrolysis increased by 13.08% and 80.37%,respectively,compared to those of the non-densified composite.High-temperature oxidation and flame tests demonstrate exceptional thermal and oxidative stability.Furthermore,when compared with carbon fiber-reinforced ceramic matrix composites,the developed composite exhibits a permittivity at least two levels lower and a reflection loss below7 dB within the frequency range of 9.3-10.9 GHz,underscoring its superior electromagnetic stealth performance.展开更多
In this paper,we perform a follow-up investigation of the solar eruption originating from active region 13575 on 2024 February 9.The primary eruption of a hot channel generates an X3.4 class flare,a full-halo coronal ...In this paper,we perform a follow-up investigation of the solar eruption originating from active region 13575 on 2024 February 9.The primary eruption of a hot channel generates an X3.4 class flare,a full-halo coronal mass ejection(CME),and an extreme-ultraviolet(EUV)wave.Interaction between the wave and a quiescent prominence(QP)leads to a large-amplitude,transverse oscillation of QP.After the transverse oscillation,QP loses equilibrium and rises up.The ascending motion of the prominence is coherently detected and tracked up to∼1.68 R_(⊙)by the Solar UltraViolet Imager onboard the GOES-16 spacecraft and up to∼2.2 R_(⊙)by the Solar Corona Imager(SCI_UV)of the LyαSolar Telescope onboard the ASO-S spacecraft.The velocity increases linearly from 12.3 to 68.5 km s^(−1)at 18:30 UT.The sympathetic eruption of QP drives the second CME with a typical three-part structure.The bright core comes from the eruptive prominence,which could be further observed up to∼3.3 R_(⊙) by the Large Angle Spectroscopic Coronagraph onboard the Solar and Heliospheric Observatory mission.The leading edge of the second CME accelerates continuously from∼120 to∼277 km s^(−1).The EUV wave plays an important role in linking the primary eruption with the sympathetic eruption.展开更多
OBJECTIVE:To reveal the antidepressant mechanisms of Jiawei DanZhiXiaoYaoSan(加味丹栀逍遥散,JD)in chronic unpredictable mild stress(CUMS)-induced depression in mice.METHODS:Using the CUMS mouse model of depression,the...OBJECTIVE:To reveal the antidepressant mechanisms of Jiawei DanZhiXiaoYaoSan(加味丹栀逍遥散,JD)in chronic unpredictable mild stress(CUMS)-induced depression in mice.METHODS:Using the CUMS mouse model of depression,the antidepressant effects of JD were assessed using the sucrose preference test(SPT),forced swimming test(FST),and tail suspension test(TST).Tandem mass tag(TMT)-based quantitative proteomic analysis of the brain was performed following JD treatment.Hierarchical clustering,Gene Ontology function annotation,Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment,and protein-protein interactions(PPIs)were used to analyze differentially expressed proteins(DEPs),which were further validated using quantitative real-time polymerase chain reaction(qR T-PCR)and Western blotting.RESULTS:Behavioral tests confirmed the antidepressant effects of JD,and bioinformatics analysis revealed 59 DEPs,including 33 up-regulated and 26 down-regulated proteins,between the CUMS and JD-M groups.KEGG and PPI analyses revealed that neurofilament proteins and the Ras signaling pathway may be key targets of JD in the treatment of depression.q RTPCR and Western blotting results demonstrated that CUMS reduced the protein expression of neurofilament light(NEFL)and medium(NEFM)and inhibited the phosphorylation of extracellular regulated kinase 1/2(ERK1/2),whereas JD promoted the phosphorylation of ERK1/2 and up-regulated the protein expression of NEFL and NEFM.CONCLUSIONS:The antidepressant mechanism of JD may be related to the up-regulation of p-ERK1/2 and neurofilament proteins.展开更多
Monitoring minuscule mechanical signals,both in magnitude and direction,is imperative in many application scenarios,e.g.,structural health monitoring and robotic sensing systems.However,the piezoelectric sensor strugg...Monitoring minuscule mechanical signals,both in magnitude and direction,is imperative in many application scenarios,e.g.,structural health monitoring and robotic sensing systems.However,the piezoelectric sensor struggles to satisfy the requirements for directional recognition due to the limited piezoelectric coefficient matrix,and achieving sensitivity for detecting micrometer-scale deformations is also challenging.Herein,we develop a vector sensor composed of lead zirconate titanate-electronic grade glass fiber composite filaments with oriented arrangement,capable of detecting minute anisotropic deformations.The as-prepared vector sensor can identify the deformation directions even when subjected to an unprecedented nominal strain of 0.06%,thereby enabling its utility in accurately discerning the 5μm-height wrinkles in thin films and in monitoring human pulse waves.The ultra-high sensitivity is attributed to the formation of porous ferroelectret and the efficient load transfer efficiency of continuous lead zirconate titanate phase.Additionally,when integrated with machine learning techniques,the sensor’s capability to recognize multi-signals enables it to differentiate between 10 types of fine textures with 100%accuracy.The structural design in piezoelectric devices enables a more comprehensive perception of mechanical stimuli,offering a novel perspective for enhancing recognition accuracy.展开更多
Carbon fibres have been produced from hydroxypropyl-modified lignin(TcC)/bio-based polyamide 1010(PA1010)blended filaments.Two grades of PA1010,with different molecular weights and rheological properties,were used for...Carbon fibres have been produced from hydroxypropyl-modified lignin(TcC)/bio-based polyamide 1010(PA1010)blended filaments.Two grades of PA1010,with different molecular weights and rheological properties,were used for blending with TcC.An oxidative thermal stabilisation step was used prior to carbonisation in an inert atmosphere to prevent the fusion of the filaments during the latter step.Thermal stabilisation was not possible using a one-step stabilisation process reported in the literature for lignin and other lignin/synthetic polymer blends.As a consequence,a cyclic process involving an additional isothermal phase at a lower temperature than the precursor filaments’melting point,was introduced to increase the cross-linking reactions between the lignin and polyamide.Thermally stabilised filaments were characterised by DSC,TGA,TGA-FTIR,ATR,and SEM techniques.Polymer rheology and heating rate used during thermal stabilisation influenced the thermal stabilisation process and mechanical properties of the derived filaments.Thermally stabilised filaments using optimised conditions(heating in the air atmosphere at 0.25℃/min to 180℃;isothermal for 1 h,cooling back down to ambient at 5℃/min;heating to 250℃ at 0.25℃/min,isothermal for 2 h)could be successfully carbonised.Carbon fibres pro-duced had void-free morphologies and mechanical properties comparable to similarly thermally stabilised and carbonised polyacrylonitrile(PAN)filaments.展开更多
Wattwil,Switzerland,April l,2025-The art of re-orientation runs through Heberlein's l90-year companyhistory.Georg Philipp Heberlein and his descendants ranan exemplary family business with roots in yarn dyeing.Itd...Wattwil,Switzerland,April l,2025-The art of re-orientation runs through Heberlein's l90-year companyhistory.Georg Philipp Heberlein and his descendants ranan exemplary family business with roots in yarn dyeing.Itdeveloped into a corporate group and ultimately became ahighly spectalised company that is regarded as the world'sleading provider of air interlacing and air texturing jets forsynthetic continuous filament yarns.展开更多
Freshwater ecosystems are crucial in the global emissions of greenhouse gases(GHGs)such as CH_(4).Macrophytes are the main organic matter(i.e.,detritus)supplier to the sediment of these systems,thus controlling CH_(4)...Freshwater ecosystems are crucial in the global emissions of greenhouse gases(GHGs)such as CH_(4).Macrophytes are the main organic matter(i.e.,detritus)supplier to the sediment of these systems,thus controlling CH_(4) production.However,species-specific differences(structure and composition)may determine contrasting patterns of detritus transformation into CH_(4).Furthermore,eutrophication can affect the degradation and,consequently,CH_(4) production.We performed a 64-day microcosm experiment with anoxic incubations of detritus from seven phylogenetically different macrophytes(two charophytes,filamentous algae–Spirogyra,Cladophora–,three submerged plants and an amphibious one),under two trophic conditions(oligo-versus eutrophic)and with/without sediment.We assessed the CH_(4) and CO_(2) production and the changes in the detritus quality at the end of the experiment.The ranking in the mean cumulative CH_(4) production was:Chara hispida>Nitella hyalina>Najasmarina≈Teucrium scordium>Stuckenia pectinata≈Myriophyllum spicatum>filamentous algae,and it was related to the detritus quality.GHGs maximumproduction rates were 1.6(N.marina)-1.2(C.hispida)mmol CH_(4)/(g OC·day)and 1.7(N.marina)-1.5(C.hispida)mmol CO_(2)/(g OC·day).The CO_(2):CH_(4) ratiowas biased towards CO_(2) during the first 10 days(average ratio of 200)and fell afterwards to about 1 for all macrophyte species and treatments.The sediment favored detritus decomposition(probably due to the“positive priming effect”),increasing GHGs production.The influence of nutrient enrichment was not evident.Delving into themacrophyte detritus quality-GHGs production relationship is needed to forecast the GHGs emissions in macrophyte-dominated systems.展开更多
Alkaline stress in saline soil limits cotton production that may be improved by using emerging nanobiotechnology approaches.Here,we applied poly acrylic acid coated Mn3O4 nanoparticles(PMO)on cotton leaves which showe...Alkaline stress in saline soil limits cotton production that may be improved by using emerging nanobiotechnology approaches.Here,we applied poly acrylic acid coated Mn3O4 nanoparticles(PMO)on cotton leaves which showed higher chlorophyll content(up to 100.0%)and fresh weight(46.9%)and lower electrolyte leakage rate(up to 6.8%)and cell death rate(up to 84.8%)than controls.Further investigation showed that PMO can maintain reactive oxygen species(ROS)homeostasis,increase the stability of actin filament(AF),and reduce Na^(+)content.Confocal imaging and ROS content measurement showed that PMO foliar application effectively alleviated ROS over-accumulation(up to 16.4%decrease for H_(2)O_(2)and 45.3%decrease for O_(2)^(•-))in cotton leaves.Moreover,under alkaline stress,genes for AF depolymerization such as GhADF1/8 and GhADF6 and for AF polymerization such as GhADF5 were significantly down-regulated in PMO treated cotton lines relative to those in the control,consistent with the fluorescence intensities of AFs.Furthermore,our results showed that PMO mitigated Na^(+)toxicity under alkaline stress,as indicated by the reduced Na^(+)fluorescence intensity and Na^(+)content.Furthermore,relative to those of the control,PMO treatment increased seed yield and lint yield by 65.0%and 66.3%respectively.Together,our work demonstrates that ROS scavenging PMO alleviated alkaline stress by stabilizing actin filaments and reducing Na^(+)toxicity.展开更多
The variations of the frontogenetic activity of cold filament driven by the different angle(θ=0°,22.5°,45°,67.5°,and 90°)of the wind and wave fields and the filament axis are studied by non h...The variations of the frontogenetic activity of cold filament driven by the different angle(θ=0°,22.5°,45°,67.5°,and 90°)of the wind and wave fields and the filament axis are studied by non hydrostatic large eddy simulation.Conversion between the frontogenesis and frontolysis of cold filament were created by the chang in the direction of secondary circulations.The changes in the direction of secondary circulation are induced by the Coriolis Effect regardless of wind direction and wave fields.The destructive action of the wind and wave fields on symmetry of the submesoscale flow fields becomes weak as the angle increases.The secondary downwelling jet induced by Stokes shear force is gradually close to that associated with secondary circulations as the angle changes fromθ=0°to 45°and then the downwelling jet is only created by secondary circulations forθ=67.5°and 90°.The frontogenetic intensity of cold filament may be impacted by the angle of the wind and wave fields and the filament axis.The reason is that firstly the odd-symmetry of secondary circulations enhances with the angle increasing,and secondary the secondary downwelling jet created the Stokes shear force gradually weakens and then disappears with the angle increasing.展开更多
BACKGROUND:The present study aims to investigate whether mannitol facilitates central nervous system(CNS) entry of vancomycin and alleviates methicillin-resistant Staphylococcus aureus(MRSA)intracranial infection.METH...BACKGROUND:The present study aims to investigate whether mannitol facilitates central nervous system(CNS) entry of vancomycin and alleviates methicillin-resistant Staphylococcus aureus(MRSA)intracranial infection.METHODS:Blood-brain barrier(BBB) permeability was assessed by measuring the concentration of sodium fl uorescein(NaF) in the brain tissues of rats and fl uorescein isothiocyanate-dextran(FITC-dextran)in a single-cell layer model.Neutrophil infiltration in the brain tissue,inflammatory cytokine levels in the serum,neurological function,and 7-day survival rates were used to evaluate therapeutic eff ects of mannitol and vancomycin in MRSA-infected rats.Syndecan-1 and fi lamentous actin(F-actin) levels were measured,and the relationship between F-actin and the endothelial glycocalyx layer(EGL) was explored via the depolymerization agent cytochalasin D and the polymerization agent jasplakinolide.RESULTS:Following mannitol administration,the NaF and vancomycin concentrations in the brain tissue increased rapidly within 5 min and remained stable for 30 min,indicating that mannitol increased BBB permeability for 30 min.In vitro,mannitol treatment led to significantly greater FITC-dextran permeation through a single-cell layer compared to controls.In the MRSA intracranial infection model,rats treated with mannitol and vancomycin simultaneously presented less infl ammation,improved neurological function,and increased 7-day survival rate compared to rats treated with vancomycin and mannitol at 10-hour intervals.Further experiments revealed that mannitol decreased the expression of syndecan-1 in brain tissues,which was confi rmed by in vitro experiments showing that mannitol signifi cantly decreased syndecan-1 via F-actin depolymerization.CONCLUSION:Mannitol may enhance the therapeutic effi cacy of vancomycin against intracranial MRSA infection by decreasing the endothelial glycocalyx of the BBB via F-actin depolymerization.展开更多
A numerical method to predict the bursting strength of filament wound composite rocket motor case is proposed here.This method can evaluate the longitudinal stress evolution of each composite layer as impregnated fila...A numerical method to predict the bursting strength of filament wound composite rocket motor case is proposed here.This method can evaluate the longitudinal stress evolution of each composite layer as impregnated filaments with fiber tension are wound layer by layer,and consider the effects of accumulated stress and deformation during filament winding on the bursting strength of composite case.Taking∅520 mm composite cases as a case study,the filament-winding-process-induced stress and deformation as well as progressive damage behavior are numerically predicted,followed by a comparison with experimental results.The numerical results show that the predicted bursting pressures for composite cases manufactured on the mandrels with and without a flexible component are 14.20 MPa and 21.40 MPa,respectively.These values exhibit slight deviation from the measured pressures of 13.50 MPa and 21.57 MPa.Moreover,the predicted damage locations,situated respectively in the dome and cylinder,agree well with the experimental observation.These observations indicate that use of flexible component reduces the load-bearing capacity of the domes.Furthermore,it validates the reliability and accuracy of the proposed numerical method in predicting the bursting strength of composite cases.展开更多
Intermediate filaments(IFs)in human cells are the products of six distinct gene families,all sharing homology in a core rod domain.These IFs assemble into non-polar polymers,providing cytoplasmic and nuclear mechanica...Intermediate filaments(IFs)in human cells are the products of six distinct gene families,all sharing homology in a core rod domain.These IFs assemble into non-polar polymers,providing cytoplasmic and nuclear mechanical support.Recent research has revealed the active and dynamic properties of IFs and their binding partners.This regulation extends beyond cell mechanics to include migration,mechanotransduction,and tumor growth.Therefore,this comprehensive review aims to catalog all human IF genes and IF-associated proteins(IFAPs),detailing their names,sizes,functions,associated human diseases,relevant literature,and links to resources like UniProt and the Protein Atlas database.These links provide access to additional information such as protein structure,subcellular localization,disease-causing mutations,and pathology.Using this catalog,we will provide an overview of the current understanding of the biological functions of IFs and IFAPs.This overview is crucial for identifying gaps in their characterization and understanding IF-mediated mechanotransduction.Additionally,we will consider potential future research directions.展开更多
Memristive devices based on in-memory computing architectures offer a promising strategy for overcoming the energy bottlenecks inherent in big data systems.However,uncontrolled ion migration at the material level rema...Memristive devices based on in-memory computing architectures offer a promising strategy for overcoming the energy bottlenecks inherent in big data systems.However,uncontrolled ion migration at the material level remains a key challenge,compromising device stability and hindering practical applications.Here,we employ a chemical optimization strategy that dynamically induces the precipitation of Ag atoms under applied voltage,creating fixed atomic sites to achieve precise control over ion migration,synergistically enhancing the memory and computing capabilities of the device.Compared to unoptimized samples,the proposed device exhibits an approximately 8-fold improvement in robustness,a 3-fold enhancement in stability,high mechanical endurance,and reliable multilevel data storage capability.We further construct a device array and incorporate an efficient reservoir computing model,achieving handwritten digit recognition with an accuracy of up to 90.81%.In summary,this work proposes a dynamic Ag/Ag^(+)anchoring strategy and demonstrates a memristor-based approach that integrates storage and computation to enable energy-efficient artificial intelligence processing,offering a scalable solution for sustainable intelligence in the big data era.展开更多
The conversion of sound vibration into electrical potential is a critical function performed by cochlear hair cells.Unlike the regenerative capacity found in various other cells throughout the body,cochlear sensory ce...The conversion of sound vibration into electrical potential is a critical function performed by cochlear hair cells.Unlike the regenerative capacity found in various other cells throughout the body,cochlear sensory cells lack the ability to regenerate once damaged.Furthermore,a decline in the quantity of these cells results in a deterioration of auditory function.Piezoelectric materials can generate electric charge in response to sound wave vibration,making them theoretically suitable for replacing hair cell function.This study explores an innovative approach using piezoelectric nanocomposite filaments,namely poly(vinylidene fluoride),poly(vinylidene fluoride)/barium titanate,and poly(vinylidene fluoride)/reduced graphene oxide,as self-powered acoustic sensors designed to function in place of cochlear hair cells.These flexible filaments demonstrate a unique ability to generate electricity in response to frequency sounds from 50 up to 1000 Hz at moderate sound pressure levels(60–95 dB),approaching the audible range with an overall acoustoelectric energy conversion efficiency of 3.25%.Serving as self-powered acoustic sensors,these flexible filaments hold promise for potential applications in cochlear implants,with a high sensitivity of 117.5 mV(Pa-cm^(2))^(-1).The cytocompatibility of these filaments was assessed through in vitro viability tests conducted on three cell lines,serving as a model for inner ear cells.展开更多
The air-sea interactions with the submesoscale warm filament of the oceanic mixed layer are simulated by a coupled atmosphere-ocean model of the parallelized lager eddy simulation model.The results show that the warm ...The air-sea interactions with the submesoscale warm filament of the oceanic mixed layer are simulated by a coupled atmosphere-ocean model of the parallelized lager eddy simulation model.The results show that the warm core of the oceanic warm filament heats the bottom air of the atmospheric boundary layer,the rise of the bottom warm air results in the formation of the atmospheric warm filament.The variation in the width of the oceanic warm filament is generated by the change in the direction of the secondary circulations.The variation in the width of the atmospheric warm filament is created by that of the oceanic warm filament,because the direction of the secondary circulations of the atmospheric warm filament is invariable with time.The Coriolis effect results in the change in the direction of the secondary circulations for the oceanic warm filament.The secondary circulations of the atmospheric warm filament are produced by the rise of the bottom warm air caused by the oceanic warm filament,which leads to the unchanged direction of the secondary circulations.The thermal convection turbulence caused by the temperature difference of the ocean and atmosphere gradually weakens the structure of the oceanic and atmospheric warm filaments.展开更多
Magnetic reconnection driving a two-sided-loop jet is typically associated with interactions between an emerging bipole and the overlying horizontal magnetic field,or between filaments from separate magnetic systems.L...Magnetic reconnection driving a two-sided-loop jet is typically associated with interactions between an emerging bipole and the overlying horizontal magnetic field,or between filaments from separate magnetic systems.Leveraging high temporal and spatial resolution observations from ground-based and space-borne instruments,we have identified a two-sided-loop jet originating from magnetic reconnection between threads within a single filament.Our observations show that as two initially crossing filamentary threads within the filament converge,reconnection takes place at their intersection.In the Doppler images,distinct redshift and blueshift signals are observed at the locations where the filament threads intersected.This process generates a two-sided-loop jet with outflow speeds of 22.2 and 62.5 km s^(-1).Following reconnection,the original crossing threads transform into two parallel threads that subsequently separate at speeds of 2.8 and 8.3kms^(-1).This observation offers a new perspective on the mechanisms responsible for jet formation.展开更多
Accidental exposure to overdose ionizing radiation will inevitably lead to severe biological damage,thus detecting and localizing radiation is essential.Traditional measurement techniques are generally restricted to t...Accidental exposure to overdose ionizing radiation will inevitably lead to severe biological damage,thus detecting and localizing radiation is essential.Traditional measurement techniques are generally restricted to the detection range of few centimeters,posing a great risk to operators.The prospect in remote sensing makes femtosecond laser filament technology a great candidate for constructively addressing this challenge.Here we propose a novel filament-based ionizing radiation sensing method,and clarify the interaction mechanism between filaments and ionizing radiation from systematic experiment to microscopic theory.Specifically,it is demonstrated that the energetic electrons produced byαradiation in air can be effectively accelerated within the filament,serving as seed electrons,which will enhance nitrogen fluorescence.The extended nitrogen fluorescence lifetime of~1 ns is also observed.Lastly,the combined microscopic model was elaborately established to quantitatively explain the modulation of nitrogen fluorescence emission from filament by ionizing radiation.These findings provide insights into the intricate interaction among ultra-strong light field,plasma and energetic particle beam,potentially suggesting a promising novel avenue for remote sensing of ionizing radiation.展开更多
Cavity-free lasing of nitrogen molecules pumped by intense femtosecond laser pulses holds the potential for remote sensing of electric fields.Here we compared the influence of an external direct current(DC)electric fi...Cavity-free lasing of nitrogen molecules pumped by intense femtosecond laser pulses holds the potential for remote sensing of electric fields.Here we compared the influence of an external direct current(DC)electric field on both the directional lasing radiation and omnidirectional fluorescence emission of neutral nitrogen molecules.It was found that the forward lasing radiation in both pure nitrogen gas and ambient air shows a sensitive dependence on the direction and strength of the DC field,while the fluorescence is not influenced.The effect of pump laser polarization was also investigated.The distinct behavior of the lasing and fluorescence in response to the DC field was attributed to their different dependences on the population distribution of excited nitrogen molecules.This study consolidates the method for standoff detection of electric field with an air lasing effect in the atmosphere.展开更多
文摘In order to optimize the reaming process of the type IV composite hydrogen storage cylinder,the netting theory was employed for the design of stacking sequences,and the thickness in the head section was predicted.A finite element model of the plastic-lined composite hydrogen storage cylinder,designed to withstand a working pressure of 70.0 MPa,was established by using the wound composite modeler(WCM)in the Abaqus software to analyze the forces acting on the winding layer.The Hashin failure criterion was utilized as the standard for assessing composite failure,and a progressive failure analysis of the cylinder was conducted to predict both the bursting pressure and the failure location of the composite hydrogen storage cylinder.The results indicate that the reaming process can effectively reduce the maximum filament winding thickness in the head section and promote a more uniform transition.At the bursting pressure,the stress within the head liner decreases,thereby enhancing the ultimate bearing capacity of the cylinder.A control system for a four-axis winding machine was designed by utilizing an industrial computer and a programmable multi-axis controller(PMAC).The winding line pattern is designed and the G-code trajectory is generated by the industrial computer.The numerical control system,composed of the PMAC and servo motor,executes the four-axis interpolation motion.
基金Supported by the Science and Technology Innovation Project of Laoshan Laboratory(Nos.2022QNLM030004-3,LSKJ202203103)the NSFC Innovative Group Grant(No.42221005)+5 种基金the Key Collaborative Research Program of the Alliance of International Science Organizations(No.ANSO-CR-KP-2022-08)the Shandong Provincial Natural Science Foundation(No.ZR2021ZD28)the Major Research Plan of the National Natural Science Foundation(No.92351301)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA22050301)the Taishan Scholars Program(No.tstp20230637)the Qingdao Natural Science Foundation(No.23-2-1-182-zyyd-jch)。
文摘With the increasing accumulation of plastic pollutants in various environments,research on microorganisms(including bacteria,fungi,and algae)with plastic degradation capabilities has gained significant attention.However,only a limited number of microbial plastic-degrading enzymes have been identified to date.This highlights that the degradation mechanisms employed by many plastic-degrading microorganisms,particularly filamentous fungi,remain insufficiently explored.In this study,we utilized a versatile fungal plasmid(pCT74)to express green fluorescent protein(GFP)in a marine-derived fungus Alternaria alternata strain FB1 with plastic degradation capabilities.Upon evaluating the degradation effect of polyester-type polyurethane(PU)film,we observed that different transformants exhibited three kinds of activities(the same,reduced,or enhanced degradation capability)compared to the FB1 wild-type strain.Further analysis of the plasmid fragment insertion sites in different transformants revealed that pCT74 integrates randomly into the genome of the host fungus.Notably,a direct correlation was found between the plasmid insertion site and the degradation capability of the corresponding transformant.Our findings not only redefine the potential applications of plasmid pCT74 in filamentous fungi but also show a novel research approach to identifying key enzymes involved in plastic degradation by fungi.
基金supported by the Agency for Defense Development Grant Funded by the Korean Government(Grant No.912822501).
文摘Unmanned combat aerial vehicles require lightweight,stealth-capable exhaust systems.However,traditional metallic nozzles increase radar detectability and reduce range,while advanced composites offer high performance but are expensive.Therefore,to improve the operational range and survivability of unmanned combat aerial vehicles,a lightweight,high-temperature-resistant,oxidation-resistant,and low-observable composite exhaust nozzle is developed to replace conventional metallic straight-type nozzles.The nozzle features a double serpentine shape to reduce radar and infrared signatures and is manufactured as a monolithic structure using the filament winding process,accommodating the complex geometry and large size(length:1.8 m,width:0.8 m).The exhaust nozzle consists of a ceramic matrix composite made of silicon carbide fibers and a silicon oxycarbide matrix,which absorbs and scatters radio frequency signals while withstanding prolonged exposure to high-temperature(700℃)oxidizing environments typical of engine exhaust gases.The polysiloxane resin used to produce the silicon oxycarbide matrix poses significant challenges owing to its low tackiness and high viscosity variations depending on the presence of nanoparticles,making filament winding difficult.These challenges are addressed by optimizing resin viscosity and winding pattern design.As a result,the tensile strength of the composite specimens fabricated with the optimized viscosity increases by 228.03% before pyrolysis and 97.68%after pyrolysis,compared with that of the non-optimized specimens.In addition,the density and tensile strength of the composite processed via three cycles of polymer infiltration and pyrolysis increased by 13.08% and 80.37%,respectively,compared to those of the non-densified composite.High-temperature oxidation and flame tests demonstrate exceptional thermal and oxidative stability.Furthermore,when compared with carbon fiber-reinforced ceramic matrix composites,the developed composite exhibits a permittivity at least two levels lower and a reflection loss below7 dB within the frequency range of 9.3-10.9 GHz,underscoring its superior electromagnetic stealth performance.
基金supported by the Strategic Priority Research Program on Space Science,Chinese Academy of Sciencessupported by the National Key R&D Program of China 2022YFF0503003(2022YFF0503000),2021YFA1600500 (2021YFA1600502)+3 种基金the Strategic Priority Research Program of the Chinese Academy of Sciences,grant No.XDB0560000the National Natural Science Foundation of China (NSFC,grant Nos.12373065,12203102,12403064,and 12403068)Natural Science Foundation of Jiangsu Province (BK20231510,BK20241707)Supported by the Specialized Research Fund for State Key Laboratories,and Yunnan Key Laboratory of Solar Physics and Space Science under the grant No.YNSPCC202206
文摘In this paper,we perform a follow-up investigation of the solar eruption originating from active region 13575 on 2024 February 9.The primary eruption of a hot channel generates an X3.4 class flare,a full-halo coronal mass ejection(CME),and an extreme-ultraviolet(EUV)wave.Interaction between the wave and a quiescent prominence(QP)leads to a large-amplitude,transverse oscillation of QP.After the transverse oscillation,QP loses equilibrium and rises up.The ascending motion of the prominence is coherently detected and tracked up to∼1.68 R_(⊙)by the Solar UltraViolet Imager onboard the GOES-16 spacecraft and up to∼2.2 R_(⊙)by the Solar Corona Imager(SCI_UV)of the LyαSolar Telescope onboard the ASO-S spacecraft.The velocity increases linearly from 12.3 to 68.5 km s^(−1)at 18:30 UT.The sympathetic eruption of QP drives the second CME with a typical three-part structure.The bright core comes from the eruptive prominence,which could be further observed up to∼3.3 R_(⊙) by the Large Angle Spectroscopic Coronagraph onboard the Solar and Heliospheric Observatory mission.The leading edge of the second CME accelerates continuously from∼120 to∼277 km s^(−1).The EUV wave plays an important role in linking the primary eruption with the sympathetic eruption.
基金the National Natural Science Foundation of China:Study on the Biological Basis of Jiawei Danzhi Xiaoyaosan in Treatment of Depression based on Network Pharmacology and Proteomics(No.81973739)Natural Science Excellent Youth Fund of Henan Province:the Mechanism of Baicalin Regulates the GSK3B-Mediated Axoplasmic Transport in the Treatment of Depression(No.202300410249)+1 种基金Science and Technology Research Project of Henan Province:Study on the Antidepressant Mechanism of Jiawei Danzhi Xiaoyaosan based on the NOD-like Receptor Thermal Protein Domainassociated Protein and Tripartite Motif-containing Protein 31 Ubiquitination Pathway(No.222102310233)Study on the Mechanism of Jiawei Danzhi Xiaoyaosan in the Treatment of Depression by Regulating M1/M2 Polarization and Microglia Autophagy(No.232102310419)。
文摘OBJECTIVE:To reveal the antidepressant mechanisms of Jiawei DanZhiXiaoYaoSan(加味丹栀逍遥散,JD)in chronic unpredictable mild stress(CUMS)-induced depression in mice.METHODS:Using the CUMS mouse model of depression,the antidepressant effects of JD were assessed using the sucrose preference test(SPT),forced swimming test(FST),and tail suspension test(TST).Tandem mass tag(TMT)-based quantitative proteomic analysis of the brain was performed following JD treatment.Hierarchical clustering,Gene Ontology function annotation,Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment,and protein-protein interactions(PPIs)were used to analyze differentially expressed proteins(DEPs),which were further validated using quantitative real-time polymerase chain reaction(qR T-PCR)and Western blotting.RESULTS:Behavioral tests confirmed the antidepressant effects of JD,and bioinformatics analysis revealed 59 DEPs,including 33 up-regulated and 26 down-regulated proteins,between the CUMS and JD-M groups.KEGG and PPI analyses revealed that neurofilament proteins and the Ras signaling pathway may be key targets of JD in the treatment of depression.q RTPCR and Western blotting results demonstrated that CUMS reduced the protein expression of neurofilament light(NEFL)and medium(NEFM)and inhibited the phosphorylation of extracellular regulated kinase 1/2(ERK1/2),whereas JD promoted the phosphorylation of ERK1/2 and up-regulated the protein expression of NEFL and NEFM.CONCLUSIONS:The antidepressant mechanism of JD may be related to the up-regulation of p-ERK1/2 and neurofilament proteins.
基金financially supported by the National Key Research and Development Program of China(No.2022YFA1205300 and No.2022YFA1205304)the Oceanic Interdisciplinary Program of Shanghai Jiao Tong University(SL2022ZD103).
文摘Monitoring minuscule mechanical signals,both in magnitude and direction,is imperative in many application scenarios,e.g.,structural health monitoring and robotic sensing systems.However,the piezoelectric sensor struggles to satisfy the requirements for directional recognition due to the limited piezoelectric coefficient matrix,and achieving sensitivity for detecting micrometer-scale deformations is also challenging.Herein,we develop a vector sensor composed of lead zirconate titanate-electronic grade glass fiber composite filaments with oriented arrangement,capable of detecting minute anisotropic deformations.The as-prepared vector sensor can identify the deformation directions even when subjected to an unprecedented nominal strain of 0.06%,thereby enabling its utility in accurately discerning the 5μm-height wrinkles in thin films and in monitoring human pulse waves.The ultra-high sensitivity is attributed to the formation of porous ferroelectret and the efficient load transfer efficiency of continuous lead zirconate titanate phase.Additionally,when integrated with machine learning techniques,the sensor’s capability to recognize multi-signals enables it to differentiate between 10 types of fine textures with 100%accuracy.The structural design in piezoelectric devices enables a more comprehensive perception of mechanical stimuli,offering a novel perspective for enhancing recognition accuracy.
文摘Carbon fibres have been produced from hydroxypropyl-modified lignin(TcC)/bio-based polyamide 1010(PA1010)blended filaments.Two grades of PA1010,with different molecular weights and rheological properties,were used for blending with TcC.An oxidative thermal stabilisation step was used prior to carbonisation in an inert atmosphere to prevent the fusion of the filaments during the latter step.Thermal stabilisation was not possible using a one-step stabilisation process reported in the literature for lignin and other lignin/synthetic polymer blends.As a consequence,a cyclic process involving an additional isothermal phase at a lower temperature than the precursor filaments’melting point,was introduced to increase the cross-linking reactions between the lignin and polyamide.Thermally stabilised filaments were characterised by DSC,TGA,TGA-FTIR,ATR,and SEM techniques.Polymer rheology and heating rate used during thermal stabilisation influenced the thermal stabilisation process and mechanical properties of the derived filaments.Thermally stabilised filaments using optimised conditions(heating in the air atmosphere at 0.25℃/min to 180℃;isothermal for 1 h,cooling back down to ambient at 5℃/min;heating to 250℃ at 0.25℃/min,isothermal for 2 h)could be successfully carbonised.Carbon fibres pro-duced had void-free morphologies and mechanical properties comparable to similarly thermally stabilised and carbonised polyacrylonitrile(PAN)filaments.
文摘Wattwil,Switzerland,April l,2025-The art of re-orientation runs through Heberlein's l90-year companyhistory.Georg Philipp Heberlein and his descendants ranan exemplary family business with roots in yarn dyeing.Itdeveloped into a corporate group and ultimately became ahighly spectalised company that is regarded as the world'sleading provider of air interlacing and air texturing jets forsynthetic continuous filament yarns.
基金supported by Spanish Ministry of Science and Innovation (No.PID2020–116147GB-C22)funded by the European Union (Next Generation UE)+1 种基金funded by the Programa de Posgrado en Ciencias del Mar y Limnología (UNAM)CONAHCYT (CVU:828722).
文摘Freshwater ecosystems are crucial in the global emissions of greenhouse gases(GHGs)such as CH_(4).Macrophytes are the main organic matter(i.e.,detritus)supplier to the sediment of these systems,thus controlling CH_(4) production.However,species-specific differences(structure and composition)may determine contrasting patterns of detritus transformation into CH_(4).Furthermore,eutrophication can affect the degradation and,consequently,CH_(4) production.We performed a 64-day microcosm experiment with anoxic incubations of detritus from seven phylogenetically different macrophytes(two charophytes,filamentous algae–Spirogyra,Cladophora–,three submerged plants and an amphibious one),under two trophic conditions(oligo-versus eutrophic)and with/without sediment.We assessed the CH_(4) and CO_(2) production and the changes in the detritus quality at the end of the experiment.The ranking in the mean cumulative CH_(4) production was:Chara hispida>Nitella hyalina>Najasmarina≈Teucrium scordium>Stuckenia pectinata≈Myriophyllum spicatum>filamentous algae,and it was related to the detritus quality.GHGs maximumproduction rates were 1.6(N.marina)-1.2(C.hispida)mmol CH_(4)/(g OC·day)and 1.7(N.marina)-1.5(C.hispida)mmol CO_(2)/(g OC·day).The CO_(2):CH_(4) ratiowas biased towards CO_(2) during the first 10 days(average ratio of 200)and fell afterwards to about 1 for all macrophyte species and treatments.The sediment favored detritus decomposition(probably due to the“positive priming effect”),increasing GHGs production.The influence of nutrient enrichment was not evident.Delving into themacrophyte detritus quality-GHGs production relationship is needed to forecast the GHGs emissions in macrophyte-dominated systems.
基金supported by the National Natural Science Foundation of China(32120103008)the National Key Research and Development Program of China(2023YFD1901700-3)+3 种基金Fundamental Research Funds for the Central Universities(2662024JC011,2662025HXPY005)the HZAU-AGIS Fund(SZYJY2021008)the Key Research and Development Projects of Henan province(231111113000)the Hubei Agricultural Science and Technology Innovation Center Program(2021-620-000-001-032).
文摘Alkaline stress in saline soil limits cotton production that may be improved by using emerging nanobiotechnology approaches.Here,we applied poly acrylic acid coated Mn3O4 nanoparticles(PMO)on cotton leaves which showed higher chlorophyll content(up to 100.0%)and fresh weight(46.9%)and lower electrolyte leakage rate(up to 6.8%)and cell death rate(up to 84.8%)than controls.Further investigation showed that PMO can maintain reactive oxygen species(ROS)homeostasis,increase the stability of actin filament(AF),and reduce Na^(+)content.Confocal imaging and ROS content measurement showed that PMO foliar application effectively alleviated ROS over-accumulation(up to 16.4%decrease for H_(2)O_(2)and 45.3%decrease for O_(2)^(•-))in cotton leaves.Moreover,under alkaline stress,genes for AF depolymerization such as GhADF1/8 and GhADF6 and for AF polymerization such as GhADF5 were significantly down-regulated in PMO treated cotton lines relative to those in the control,consistent with the fluorescence intensities of AFs.Furthermore,our results showed that PMO mitigated Na^(+)toxicity under alkaline stress,as indicated by the reduced Na^(+)fluorescence intensity and Na^(+)content.Furthermore,relative to those of the control,PMO treatment increased seed yield and lint yield by 65.0%and 66.3%respectively.Together,our work demonstrates that ROS scavenging PMO alleviated alkaline stress by stabilizing actin filaments and reducing Na^(+)toxicity.
基金Supported by the National Natural Science Foundation of China (Nos.92158204,42176027,41876017,42076026)the project supported by Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)(No.SML2023SP240)+1 种基金the Open Research Project Program of the State Key Laboratory of Internet of Things for Smart City (University of Macao)(No.SKL-IoTSC (UM)-2021-2023/ORPF/A20/2022)the Postdoctoral Innovation Practice Base of Hezhu University and the Guangxi Yuchai New Energy Co.,Ltd.。
文摘The variations of the frontogenetic activity of cold filament driven by the different angle(θ=0°,22.5°,45°,67.5°,and 90°)of the wind and wave fields and the filament axis are studied by non hydrostatic large eddy simulation.Conversion between the frontogenesis and frontolysis of cold filament were created by the chang in the direction of secondary circulations.The changes in the direction of secondary circulation are induced by the Coriolis Effect regardless of wind direction and wave fields.The destructive action of the wind and wave fields on symmetry of the submesoscale flow fields becomes weak as the angle increases.The secondary downwelling jet induced by Stokes shear force is gradually close to that associated with secondary circulations as the angle changes fromθ=0°to 45°and then the downwelling jet is only created by secondary circulations forθ=67.5°and 90°.The frontogenetic intensity of cold filament may be impacted by the angle of the wind and wave fields and the filament axis.The reason is that firstly the odd-symmetry of secondary circulations enhances with the angle increasing,and secondary the secondary downwelling jet created the Stokes shear force gradually weakens and then disappears with the angle increasing.
基金supported by the National Natural Science Foundation for Young Scientists of China (grant no.2002074)the Natural Science Foundation of Guangdong Province(2023A1515010267, 2023A1515012665, 2024A1515010073)+1 种基金the China International Medical Foundation Cerebrovascular Disease Youth Innovation Fund (Z-2016-20-2201)the Medical Leading Talents Fund of Guangdong Province (KJ012019430)。
文摘BACKGROUND:The present study aims to investigate whether mannitol facilitates central nervous system(CNS) entry of vancomycin and alleviates methicillin-resistant Staphylococcus aureus(MRSA)intracranial infection.METHODS:Blood-brain barrier(BBB) permeability was assessed by measuring the concentration of sodium fl uorescein(NaF) in the brain tissues of rats and fl uorescein isothiocyanate-dextran(FITC-dextran)in a single-cell layer model.Neutrophil infiltration in the brain tissue,inflammatory cytokine levels in the serum,neurological function,and 7-day survival rates were used to evaluate therapeutic eff ects of mannitol and vancomycin in MRSA-infected rats.Syndecan-1 and fi lamentous actin(F-actin) levels were measured,and the relationship between F-actin and the endothelial glycocalyx layer(EGL) was explored via the depolymerization agent cytochalasin D and the polymerization agent jasplakinolide.RESULTS:Following mannitol administration,the NaF and vancomycin concentrations in the brain tissue increased rapidly within 5 min and remained stable for 30 min,indicating that mannitol increased BBB permeability for 30 min.In vitro,mannitol treatment led to significantly greater FITC-dextran permeation through a single-cell layer compared to controls.In the MRSA intracranial infection model,rats treated with mannitol and vancomycin simultaneously presented less infl ammation,improved neurological function,and increased 7-day survival rate compared to rats treated with vancomycin and mannitol at 10-hour intervals.Further experiments revealed that mannitol decreased the expression of syndecan-1 in brain tissues,which was confi rmed by in vitro experiments showing that mannitol signifi cantly decreased syndecan-1 via F-actin depolymerization.CONCLUSION:Mannitol may enhance the therapeutic effi cacy of vancomycin against intracranial MRSA infection by decreasing the endothelial glycocalyx of the BBB via F-actin depolymerization.
基金supported by the National Natural Science Foundation of China(No.11902231)the Major Program(JD)of Hubei Province,China(No.2023BAA004).
文摘A numerical method to predict the bursting strength of filament wound composite rocket motor case is proposed here.This method can evaluate the longitudinal stress evolution of each composite layer as impregnated filaments with fiber tension are wound layer by layer,and consider the effects of accumulated stress and deformation during filament winding on the bursting strength of composite case.Taking∅520 mm composite cases as a case study,the filament-winding-process-induced stress and deformation as well as progressive damage behavior are numerically predicted,followed by a comparison with experimental results.The numerical results show that the predicted bursting pressures for composite cases manufactured on the mandrels with and without a flexible component are 14.20 MPa and 21.40 MPa,respectively.These values exhibit slight deviation from the measured pressures of 13.50 MPa and 21.57 MPa.Moreover,the predicted damage locations,situated respectively in the dome and cylinder,agree well with the experimental observation.These observations indicate that use of flexible component reduces the load-bearing capacity of the domes.Furthermore,it validates the reliability and accuracy of the proposed numerical method in predicting the bursting strength of composite cases.
基金the National Natural Science Foundation of China(Grant No.32070777 to F.N.).
文摘Intermediate filaments(IFs)in human cells are the products of six distinct gene families,all sharing homology in a core rod domain.These IFs assemble into non-polar polymers,providing cytoplasmic and nuclear mechanical support.Recent research has revealed the active and dynamic properties of IFs and their binding partners.This regulation extends beyond cell mechanics to include migration,mechanotransduction,and tumor growth.Therefore,this comprehensive review aims to catalog all human IF genes and IF-associated proteins(IFAPs),detailing their names,sizes,functions,associated human diseases,relevant literature,and links to resources like UniProt and the Protein Atlas database.These links provide access to additional information such as protein structure,subcellular localization,disease-causing mutations,and pathology.Using this catalog,we will provide an overview of the current understanding of the biological functions of IFs and IFAPs.This overview is crucial for identifying gaps in their characterization and understanding IF-mediated mechanotransduction.Additionally,we will consider potential future research directions.
基金supported by the National Natural Science Foundation of China(NSFC,no.61804063)the Natural Science Foundation of Jilin Province(nos.YDZJ202401307ZYTS and 20220201070GX)。
文摘Memristive devices based on in-memory computing architectures offer a promising strategy for overcoming the energy bottlenecks inherent in big data systems.However,uncontrolled ion migration at the material level remains a key challenge,compromising device stability and hindering practical applications.Here,we employ a chemical optimization strategy that dynamically induces the precipitation of Ag atoms under applied voltage,creating fixed atomic sites to achieve precise control over ion migration,synergistically enhancing the memory and computing capabilities of the device.Compared to unoptimized samples,the proposed device exhibits an approximately 8-fold improvement in robustness,a 3-fold enhancement in stability,high mechanical endurance,and reliable multilevel data storage capability.We further construct a device array and incorporate an efficient reservoir computing model,achieving handwritten digit recognition with an accuracy of up to 90.81%.In summary,this work proposes a dynamic Ag/Ag^(+)anchoring strategy and demonstrates a memristor-based approach that integrates storage and computation to enable energy-efficient artificial intelligence processing,offering a scalable solution for sustainable intelligence in the big data era.
基金financial support received from Deakin University through the Alfred Deakin Postdoctoral Research Fellowship(2022)partially funded by the European Union–Next-Generation EU via the Italian Ministry of University and Research(MUR),PRIN 2022 Program(PROMISE project,CUP 153D23004700006)+1 种基金support from the Australian National Fabrication Facility(ANFF)the ARC Research Hub for Future Fibres.
文摘The conversion of sound vibration into electrical potential is a critical function performed by cochlear hair cells.Unlike the regenerative capacity found in various other cells throughout the body,cochlear sensory cells lack the ability to regenerate once damaged.Furthermore,a decline in the quantity of these cells results in a deterioration of auditory function.Piezoelectric materials can generate electric charge in response to sound wave vibration,making them theoretically suitable for replacing hair cell function.This study explores an innovative approach using piezoelectric nanocomposite filaments,namely poly(vinylidene fluoride),poly(vinylidene fluoride)/barium titanate,and poly(vinylidene fluoride)/reduced graphene oxide,as self-powered acoustic sensors designed to function in place of cochlear hair cells.These flexible filaments demonstrate a unique ability to generate electricity in response to frequency sounds from 50 up to 1000 Hz at moderate sound pressure levels(60–95 dB),approaching the audible range with an overall acoustoelectric energy conversion efficiency of 3.25%.Serving as self-powered acoustic sensors,these flexible filaments hold promise for potential applications in cochlear implants,with a high sensitivity of 117.5 mV(Pa-cm^(2))^(-1).The cytocompatibility of these filaments was assessed through in vitro viability tests conducted on three cell lines,serving as a model for inner ear cells.
基金The Scientific Research Fund for Doctor/Professor of Hezhou University under contract No.2024BSQD01the National Natural Science Foundation of China under contract No.42466001the project supported by Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)under contract No.SML2023SP240。
文摘The air-sea interactions with the submesoscale warm filament of the oceanic mixed layer are simulated by a coupled atmosphere-ocean model of the parallelized lager eddy simulation model.The results show that the warm core of the oceanic warm filament heats the bottom air of the atmospheric boundary layer,the rise of the bottom warm air results in the formation of the atmospheric warm filament.The variation in the width of the oceanic warm filament is generated by the change in the direction of the secondary circulations.The variation in the width of the atmospheric warm filament is created by that of the oceanic warm filament,because the direction of the secondary circulations of the atmospheric warm filament is invariable with time.The Coriolis effect results in the change in the direction of the secondary circulations for the oceanic warm filament.The secondary circulations of the atmospheric warm filament are produced by the rise of the bottom warm air caused by the oceanic warm filament,which leads to the unchanged direction of the secondary circulations.The thermal convection turbulence caused by the temperature difference of the ocean and atmosphere gradually weakens the structure of the oceanic and atmospheric warm filaments.
基金supported by the National Natural Science Foundation of China(NSFC,grant Nos.12303062 and 12203043)the Sichuan Science and Technology Program(2023NSFSC1351,2025ZNSFSC0315)+1 种基金Key Laboratory of Detection and Application of Space Effect in Southwest Sichuan at Leshan Normal University,Education Department of Sichuan Province(No.ZDXM20241002)Project Supported by the Specialized Research Fund for State Key Laboratory of Solar Activity and Space Weather。
文摘Magnetic reconnection driving a two-sided-loop jet is typically associated with interactions between an emerging bipole and the overlying horizontal magnetic field,or between filaments from separate magnetic systems.Leveraging high temporal and spatial resolution observations from ground-based and space-borne instruments,we have identified a two-sided-loop jet originating from magnetic reconnection between threads within a single filament.Our observations show that as two initially crossing filamentary threads within the filament converge,reconnection takes place at their intersection.In the Doppler images,distinct redshift and blueshift signals are observed at the locations where the filament threads intersected.This process generates a two-sided-loop jet with outflow speeds of 22.2 and 62.5 km s^(-1).Following reconnection,the original crossing threads transform into two parallel threads that subsequently separate at speeds of 2.8 and 8.3kms^(-1).This observation offers a new perspective on the mechanisms responsible for jet formation.
基金financial supports from National Key Research and Development Program of China(2024YFB3613900)National Natural Science Foundation of China(W2412044)+1 种基金Russian Science Foundation(25-4900154)Fundamental Research Funds for the Central Universities(63253214)。
文摘Accidental exposure to overdose ionizing radiation will inevitably lead to severe biological damage,thus detecting and localizing radiation is essential.Traditional measurement techniques are generally restricted to the detection range of few centimeters,posing a great risk to operators.The prospect in remote sensing makes femtosecond laser filament technology a great candidate for constructively addressing this challenge.Here we propose a novel filament-based ionizing radiation sensing method,and clarify the interaction mechanism between filaments and ionizing radiation from systematic experiment to microscopic theory.Specifically,it is demonstrated that the energetic electrons produced byαradiation in air can be effectively accelerated within the filament,serving as seed electrons,which will enhance nitrogen fluorescence.The extended nitrogen fluorescence lifetime of~1 ns is also observed.Lastly,the combined microscopic model was elaborately established to quantitatively explain the modulation of nitrogen fluorescence emission from filament by ionizing radiation.These findings provide insights into the intricate interaction among ultra-strong light field,plasma and energetic particle beam,potentially suggesting a promising novel avenue for remote sensing of ionizing radiation.
基金Project supported by the Natural National Science Foundation of China(Grant Nos.12034013 and 12204308)Science and Technology Commission of Shanghai Municipality(Grant No.22ZR1444100)。
文摘Cavity-free lasing of nitrogen molecules pumped by intense femtosecond laser pulses holds the potential for remote sensing of electric fields.Here we compared the influence of an external direct current(DC)electric field on both the directional lasing radiation and omnidirectional fluorescence emission of neutral nitrogen molecules.It was found that the forward lasing radiation in both pure nitrogen gas and ambient air shows a sensitive dependence on the direction and strength of the DC field,while the fluorescence is not influenced.The effect of pump laser polarization was also investigated.The distinct behavior of the lasing and fluorescence in response to the DC field was attributed to their different dependences on the population distribution of excited nitrogen molecules.This study consolidates the method for standoff detection of electric field with an air lasing effect in the atmosphere.
