Bromodomain containing 2 （Brd2） protein belongs to the Bromodomains and Extra Terminal domain （BET） family of chromatin adaptors characterized by the presence of two N-terminal tandem bromodomains and an exclusive...Bromodomain containing 2 （Brd2） protein belongs to the Bromodomains and Extra Terminal domain （BET） family of chromatin adaptors characterized by the presence of two N-terminal tandem bromodomains and an exclusive C-terminal extra terminal domain （ET） （Belkina and Denis, 2012; Shi and Vakoc, 2014）. Bromodomains are involved in recognizing acetylated histone tails and other acetylated proteins while the ET domain has been implicated in protein-protein interaction.展开更多
UNDER blue Beijing skies November＇s Asia-Pacific Economic Cooperation （APEC） Summit 2014 made a firm statement in the fight against the Ebola epidemic. The deadly disease was one of the central topics President Xi ...UNDER blue Beijing skies November＇s Asia-Pacific Economic Cooperation （APEC） Summit 2014 made a firm statement in the fight against the Ebola epidemic. The deadly disease was one of the central topics President Xi Jinping and President Barack Obama discussed during their bilateral talks on the sidelines of the APEC Informal Leaders＇ Meeting.展开更多
With a commitment to reduce emissions,and its investment in green technology bringing down global costs,China is emerging as the leader in fighting climate change.EVERYBODY knows that our world is getting hotter.They ...With a commitment to reduce emissions,and its investment in green technology bringing down global costs,China is emerging as the leader in fighting climate change.EVERYBODY knows that our world is getting hotter.They also know why.Pumping out pollutants has transformed our world into a greenhouse;heat from the sun is now trapped by a“dirty”atmosphere.展开更多
Climate change and its resulting effects on seasonality are known to alter a variety of animal behaviors including those related to foraging,phenology,and migration.Although many studies focus on the impacts of phenol...Climate change and its resulting effects on seasonality are known to alter a variety of animal behaviors including those related to foraging,phenology,and migration.Although many studies focus on the impacts of phenological changes on physiology or ftness enhancing behaviors,fewer have investigated the relationship between variation in weather and phenology on risk assessment.Fleeing from predators is an economic decision that incurs costs and benefts.As environmental conditions change,animals may face additional stressors that affect their decision to fee and infuence their ability to effectively assess risk.Flight initiation distance(FID)—the distance at which animals move away from threats—is often used to study risk assessment.FID varies due to both internal and external biotic and physical factors as well as anthropogenic activities.We asked whether variation in weather and phenology is associated with risk-taking in a population of yellow-bellied marmots(Marmota faviventer).As the air temperature increased marmots tolerated closer approaches,suggesting that they either perceived less risk or that their response to a threat was thermally compromised.The effect of temperature was relatively small and was largely dependent upon having a larger range in the full data set that permitted us to detect it.We found no effects of either the date that snow disappeared or July precipitation on marmot FID.As global temperatures continue to rise,rainfall varies more and drought becomes more common,understanding climate-related changes in how animals assess risk should be used to inform population viability models.展开更多
A lawmaker from Yucun Village in east China is fighting plastic pollution with a novel weapon and roping in young entrepreneurs as partners.WHEN lawmaker Wang Yucheng came to Beijing to attend the"two sessions&qu...A lawmaker from Yucun Village in east China is fighting plastic pollution with a novel weapon and roping in young entrepreneurs as partners.WHEN lawmaker Wang Yucheng came to Beijing to attend the"two sessions"in March,he brought something unusual with him all the way from home.It was a pencil box containing several pencils.But it was no ordinary pencil box.It was his weapon to fight environmental degradation.展开更多
To address the influence of the high-altitude low Reynolds number effect on compressors,this study investigates an axial transonic compressor through a numerical approach based on the Reynolds-averaged Navier-Stokes e...To address the influence of the high-altitude low Reynolds number effect on compressors,this study investigates an axial transonic compressor through a numerical approach based on the Reynolds-averaged Navier-Stokes equations.The entropy generation loss model and theγ-Reθttransition model are employed to analyze variations in compressor performance,flow field behavior,and flow loss under different flight altitudes.The results show that the increased flight altitude will induce a low Reynolds number effect,reducing the total pressure ratio,isentropic efficiency,peak efficiency,and compressor stall margin.Under peak efficiency conditions,the flow deflection in the rotor passage experiences a rapid decrease at altitudes above 20 km.Additionally,the separation line on the rotor suction surface and the location of the passage shock wave shift forward,leading to an expansion of the low-energy fluid range and a widening of the wake.The separation of the stator suction surface develops from a closed separation bubble at the leading edge to an open significant separation at the trailing edge.The pressure coefficient of the stator and rotor blades at the trailing edge shows a downward trend.Entropy generation increases in the spanwise and axial directions,with losses near the end walls dominating.The high-altitude low Reynolds number effect leads to a general decline in the performance of the transonic compressor and alters the flow field.展开更多
Kremlin boosts its profile with strengthened antiterrorist drive Vladimir Putin may well breathe a sigh of relief when hearing the news that Chechen rebel leader Shamil Basayev was killed. In recent years, fighting ag...Kremlin boosts its profile with strengthened antiterrorist drive Vladimir Putin may well breathe a sigh of relief when hearing the news that Chechen rebel leader Shamil Basayev was killed. In recent years, fighting against terrorism has been weighing heavily on the mind of the Russian president. Only a couple of days earlier.展开更多
SUN Baiqiu liked to read well known literature from all over the world when she was a little girl. She sympathized with the good-hearted characters and hated the greedy and the evil. She imagined that she would become...SUN Baiqiu liked to read well known literature from all over the world when she was a little girl. She sympathized with the good-hearted characters and hated the greedy and the evil. She imagined that she would become like a fairy godmother, holding a magic wand and helping the poor but kind people in distress. In 1963 she graduated from展开更多
Flight is a key feature of the reproduction and dispersal of emerging aquatic insects.However,morphological measurements of insect fight are mostly available for terrestrial taxa and dragonfies,while aquatic insects h...Flight is a key feature of the reproduction and dispersal of emerging aquatic insects.However,morphological measurements of insect fight are mostly available for terrestrial taxa and dragonfies,while aquatic insects have been poorly investigated.We analyzed 7 fight-related morphological parameters of 32 taxa belonging to 5 orders of emerging aquatic insects(Ephemeroptera,Trichoptera,Plecoptera,Diptera,and Megaloptera)with different life history traits related to fight(dispersal strategy,voltinism,adult lifespan,and swarming behavior).After correcting for allometry,we used an a priori-free approach to cluster the individuals according to their fight-related morphology.Then,we explored the levels of agreement between these clusters,taxonomy,and several life history traits of the taxa.All orders were scattered among several clusters,suggesting a large range of fight capacities,particularly for Diptera.We found swarming taxa in each cluster,showing that morphological adaptations to swarming are not identical in all aquatic insects.The clusters did not match the expected dispersal capacity of the taxa as derived from the literature or databases.Heavy wide-winged insects notably gathered taxa traditionally described as good or weak dispersers.Flight capacities based on morphology partly matched with the taxonomy and life-history traits of aquatic insect imagoes.Other parameters such as fight propensity,energy stores,and wing kinematics should help refne their fying and dispersal capacity.展开更多
Introduction Gambling in China has a long and evolving history,from ancient court cockfighting to preliberation casinos with games like baccarat.1 Over time,gambling in China has evolved to include a wide range of act...Introduction Gambling in China has a long and evolving history,from ancient court cockfighting to preliberation casinos with games like baccarat.1 Over time,gambling in China has evolved to include a wide range of activities,including gaming machines,online gambling and commercial gambling.Despite being declared illegal and regulated after the establishment of the People’s Republic of China,gambling remains deeply ingrained in Chinese culture.展开更多
The Horn of Africa,situated in the northeastern part of Africa and on the southern coast of the Gulf of Aden,faces the Arabian Peninsula across the Red Sea.Since the end of 2023,the insecure situation in the Red Sea w...The Horn of Africa,situated in the northeastern part of Africa and on the southern coast of the Gulf of Aden,faces the Arabian Peninsula across the Red Sea.Since the end of 2023,the insecure situation in the Red Sea waters near Yemen has once again exposed the vulnerability of security governance in the Horn of Africa.For a long time,the region has been mired in security predicaments.As the mainstay of security governance,global and regional organizations such as the United Nations,the African Union(AU),and the Intergovernmental Authority on Development(IGAD)have focused on peacekeeping operations.Some countries outside the region directly engage in military interventions,emphasizing“fighting violence with violence,”which further exacerbates regional instability.For the countries in the Horn of Africa,the direct impact of the Red Sea crisis on regional socio-economic development highlights the significant inadequacies in existing security governance measures.展开更多
Chakdu:A Saga of Tibet Author:Alai Paperback,328 pages Published by Long River Press Historically,Chakdu was a tiny place in Kham,one of the three traditional Tibetan-inhabited regions.Today,it is known as Xinlong,a c...Chakdu:A Saga of Tibet Author:Alai Paperback,328 pages Published by Long River Press Historically,Chakdu was a tiny place in Kham,one of the three traditional Tibetan-inhabited regions.Today,it is known as Xinlong,a county in Garze Tibetan Autonomous Prefecture,Sichuan Province,which holds a strategic position on the main transportation route from Sichuan into Xizang(Tibet).The Khampas,people of Kham,are known for their fighting fitness,and the Chakdu people are the fittest of the fit.Locals would proudly say,“The Chakdu people are made of iron.”展开更多
This paper formulates a set of three technologies that should deal with the greatest threat to mankind—climate change at the lowest cost.The main technology will be“Sunny Rain”.It considers technology to prevent er...This paper formulates a set of three technologies that should deal with the greatest threat to mankind—climate change at the lowest cost.The main technology will be“Sunny Rain”.It considers technology to prevent eruptions of submarine volcanoes at shallow depths and technologies that provide scalable and impactful solutions to reduce carbon emissions across diverse industries as complementary technologies used to reduce cost.A list of submarine volcanoes at shallow depths that are likely to spew waterborne dust into the atmosphere has begun to be created.If the governments of Japan,Italy,and Greece,which have submarine volcanoes at shallow depths(Kiki,Marsili,Columbo),prevent eruptions of these volcanoes,it will provide electricity to these countries,save many of their citizens from death,and save humanity from the greatest threat—climate change—in the most inexpensive way possible!展开更多
This article mainly analyzes the application of technical and tactical skills in mixed martial arts competitions,including mixed martial arts and its competition characteristics,the main application significance of te...This article mainly analyzes the application of technical and tactical skills in mixed martial arts competitions,including mixed martial arts and its competition characteristics,the main application significance of technical and tactical skills in mixed martial arts competitions,and its primary application strategies.It is hoped that this analysis can provide some guidelines for the appropriate application of mixed martial arts athletes’technical and tactical skills to improve their winning rate in mixed martial arts competitions.展开更多
World will see first trillionaire in next 10 years○未来10年,世界将出现第一个万亿富翁。A report says in the next ten years,the world will have its first trillionaire.The report said the wealth1 gap2?between the rich a...World will see first trillionaire in next 10 years○未来10年,世界将出现第一个万亿富翁。A report says in the next ten years,the world will have its first trillionaire.The report said the wealth1 gap2?between the rich and poor is growing.And it said we will have a trillionaire within ten years,while to fight poverty,we need more than 200 years.展开更多
A brand new method of automatic north seeking/sight stabilizing is introduced for usage in land fighting vehicles such as tank, etc. Some inertial devices are installed additionally on the platform along with relat...A brand new method of automatic north seeking/sight stabilizing is introduced for usage in land fighting vehicles such as tank, etc. Some inertial devices are installed additionally on the platform along with relative control circuits to make its function of North seeking possible. Double position calculation is adopted in this method, and by alignment at two sites the azimuth angle can be figured out. Also the orientation and the horizontal shifts of the gyro are simultaneously measured and compensated so as to improve the accuracy of north seeking. The system can automatically seek north when the vehicle is immobile. And the time consumption is no more than 5.5 min. Besides, the system can keep azimuth angle and provide tilt angle and pitch angle of the vehicle.展开更多
The paper described a newly developed high performance compressed air foam system(CAFS). The effective system generates uniform foam w ith greater momentum by injecting compressed air into flowing foam solution. Foa ...The paper described a newly developed high performance compressed air foam system(CAFS). The effective system generates uniform foam w ith greater momentum by injecting compressed air into flowing foam solution. Foa m generated by this system presented superior viscous and wetting properties to water.A pendulum system was designed to measure yield stress of foam. The results pro ved the existence of yield stress of foam. And the increasing tendency of yield stress with gas fraction and bubble size has also been found out.展开更多
基金supported by Ministry of Economy and Competitiveness,Spain(MINECO),grant number BFU2012-37304by Junta de Andalucía,Spain,grant number P12-CTS-2064
文摘Bromodomain containing 2 （Brd2） protein belongs to the Bromodomains and Extra Terminal domain （BET） family of chromatin adaptors characterized by the presence of two N-terminal tandem bromodomains and an exclusive C-terminal extra terminal domain （ET） （Belkina and Denis, 2012; Shi and Vakoc, 2014）. Bromodomains are involved in recognizing acetylated histone tails and other acetylated proteins while the ET domain has been implicated in protein-protein interaction.
文摘UNDER blue Beijing skies November＇s Asia-Pacific Economic Cooperation （APEC） Summit 2014 made a firm statement in the fight against the Ebola epidemic. The deadly disease was one of the central topics President Xi Jinping and President Barack Obama discussed during their bilateral talks on the sidelines of the APEC Informal Leaders＇ Meeting.
文摘With a commitment to reduce emissions,and its investment in green technology bringing down global costs,China is emerging as the leader in fighting climate change.EVERYBODY knows that our world is getting hotter.They also know why.Pumping out pollutants has transformed our world into a greenhouse;heat from the sun is now trapped by a“dirty”atmosphere.
基金supported by the University of Ottawa and a NSERC Discovery grant(DGECR-2019-00289,RGPIN-2019-05000)the National Geographic Society,the University of California Los Angeles(Faculty Senate and Division of Life Sciences),an RMBL research fellowship,and the U.S.National Science Foundation(NSF IDBR-0754247 and DEB-1119660 and 1557130 to D.T.B.,as well as DBI 0242960,07211346,1226713,and 1755522 to RMBL).
文摘Climate change and its resulting effects on seasonality are known to alter a variety of animal behaviors including those related to foraging,phenology,and migration.Although many studies focus on the impacts of phenological changes on physiology or ftness enhancing behaviors,fewer have investigated the relationship between variation in weather and phenology on risk assessment.Fleeing from predators is an economic decision that incurs costs and benefts.As environmental conditions change,animals may face additional stressors that affect their decision to fee and infuence their ability to effectively assess risk.Flight initiation distance(FID)—the distance at which animals move away from threats—is often used to study risk assessment.FID varies due to both internal and external biotic and physical factors as well as anthropogenic activities.We asked whether variation in weather and phenology is associated with risk-taking in a population of yellow-bellied marmots(Marmota faviventer).As the air temperature increased marmots tolerated closer approaches,suggesting that they either perceived less risk or that their response to a threat was thermally compromised.The effect of temperature was relatively small and was largely dependent upon having a larger range in the full data set that permitted us to detect it.We found no effects of either the date that snow disappeared or July precipitation on marmot FID.As global temperatures continue to rise,rainfall varies more and drought becomes more common,understanding climate-related changes in how animals assess risk should be used to inform population viability models.
文摘A lawmaker from Yucun Village in east China is fighting plastic pollution with a novel weapon and roping in young entrepreneurs as partners.WHEN lawmaker Wang Yucheng came to Beijing to attend the"two sessions"in March,he brought something unusual with him all the way from home.It was a pencil box containing several pencils.But it was no ordinary pencil box.It was his weapon to fight environmental degradation.
文摘To address the influence of the high-altitude low Reynolds number effect on compressors,this study investigates an axial transonic compressor through a numerical approach based on the Reynolds-averaged Navier-Stokes equations.The entropy generation loss model and theγ-Reθttransition model are employed to analyze variations in compressor performance,flow field behavior,and flow loss under different flight altitudes.The results show that the increased flight altitude will induce a low Reynolds number effect,reducing the total pressure ratio,isentropic efficiency,peak efficiency,and compressor stall margin.Under peak efficiency conditions,the flow deflection in the rotor passage experiences a rapid decrease at altitudes above 20 km.Additionally,the separation line on the rotor suction surface and the location of the passage shock wave shift forward,leading to an expansion of the low-energy fluid range and a widening of the wake.The separation of the stator suction surface develops from a closed separation bubble at the leading edge to an open significant separation at the trailing edge.The pressure coefficient of the stator and rotor blades at the trailing edge shows a downward trend.Entropy generation increases in the spanwise and axial directions,with losses near the end walls dominating.The high-altitude low Reynolds number effect leads to a general decline in the performance of the transonic compressor and alters the flow field.
文摘Kremlin boosts its profile with strengthened antiterrorist drive Vladimir Putin may well breathe a sigh of relief when hearing the news that Chechen rebel leader Shamil Basayev was killed. In recent years, fighting against terrorism has been weighing heavily on the mind of the Russian president. Only a couple of days earlier.
文摘SUN Baiqiu liked to read well known literature from all over the world when she was a little girl. She sympathized with the good-hearted characters and hated the greedy and the evil. She imagined that she would become like a fairy godmother, holding a magic wand and helping the poor but kind people in distress. In 1963 she graduated from
基金funded by two grants from the LTSER Zone Atelier Armorique and Earth Sciences and Astronomy Observatory(OSUR)Rennes.
文摘Flight is a key feature of the reproduction and dispersal of emerging aquatic insects.However,morphological measurements of insect fight are mostly available for terrestrial taxa and dragonfies,while aquatic insects have been poorly investigated.We analyzed 7 fight-related morphological parameters of 32 taxa belonging to 5 orders of emerging aquatic insects(Ephemeroptera,Trichoptera,Plecoptera,Diptera,and Megaloptera)with different life history traits related to fight(dispersal strategy,voltinism,adult lifespan,and swarming behavior).After correcting for allometry,we used an a priori-free approach to cluster the individuals according to their fight-related morphology.Then,we explored the levels of agreement between these clusters,taxonomy,and several life history traits of the taxa.All orders were scattered among several clusters,suggesting a large range of fight capacities,particularly for Diptera.We found swarming taxa in each cluster,showing that morphological adaptations to swarming are not identical in all aquatic insects.The clusters did not match the expected dispersal capacity of the taxa as derived from the literature or databases.Heavy wide-winged insects notably gathered taxa traditionally described as good or weak dispersers.Flight capacities based on morphology partly matched with the taxonomy and life-history traits of aquatic insect imagoes.Other parameters such as fight propensity,energy stores,and wing kinematics should help refne their fying and dispersal capacity.
基金Funding for this study was supported by National Key R&D Program of China(2023YFC3304204,2019HY320001)National Nature Science Foundation(82130041,82171484,81871045)Brain Science,Shanghai Jiao Tong University Medical Engineering Cross Research(YG2023ZD25).
文摘Introduction Gambling in China has a long and evolving history,from ancient court cockfighting to preliberation casinos with games like baccarat.1 Over time,gambling in China has evolved to include a wide range of activities,including gaming machines,online gambling and commercial gambling.Despite being declared illegal and regulated after the establishment of the People’s Republic of China,gambling remains deeply ingrained in Chinese culture.
文摘The Horn of Africa,situated in the northeastern part of Africa and on the southern coast of the Gulf of Aden,faces the Arabian Peninsula across the Red Sea.Since the end of 2023,the insecure situation in the Red Sea waters near Yemen has once again exposed the vulnerability of security governance in the Horn of Africa.For a long time,the region has been mired in security predicaments.As the mainstay of security governance,global and regional organizations such as the United Nations,the African Union(AU),and the Intergovernmental Authority on Development(IGAD)have focused on peacekeeping operations.Some countries outside the region directly engage in military interventions,emphasizing“fighting violence with violence,”which further exacerbates regional instability.For the countries in the Horn of Africa,the direct impact of the Red Sea crisis on regional socio-economic development highlights the significant inadequacies in existing security governance measures.
文摘Chakdu:A Saga of Tibet Author:Alai Paperback,328 pages Published by Long River Press Historically,Chakdu was a tiny place in Kham,one of the three traditional Tibetan-inhabited regions.Today,it is known as Xinlong,a county in Garze Tibetan Autonomous Prefecture,Sichuan Province,which holds a strategic position on the main transportation route from Sichuan into Xizang(Tibet).The Khampas,people of Kham,are known for their fighting fitness,and the Chakdu people are the fittest of the fit.Locals would proudly say,“The Chakdu people are made of iron.”
文摘This paper formulates a set of three technologies that should deal with the greatest threat to mankind—climate change at the lowest cost.The main technology will be“Sunny Rain”.It considers technology to prevent eruptions of submarine volcanoes at shallow depths and technologies that provide scalable and impactful solutions to reduce carbon emissions across diverse industries as complementary technologies used to reduce cost.A list of submarine volcanoes at shallow depths that are likely to spew waterborne dust into the atmosphere has begun to be created.If the governments of Japan,Italy,and Greece,which have submarine volcanoes at shallow depths(Kiki,Marsili,Columbo),prevent eruptions of these volcanoes,it will provide electricity to these countries,save many of their citizens from death,and save humanity from the greatest threat—climate change—in the most inexpensive way possible!
文摘This article mainly analyzes the application of technical and tactical skills in mixed martial arts competitions,including mixed martial arts and its competition characteristics,the main application significance of technical and tactical skills in mixed martial arts competitions,and its primary application strategies.It is hoped that this analysis can provide some guidelines for the appropriate application of mixed martial arts athletes’technical and tactical skills to improve their winning rate in mixed martial arts competitions.
文摘World will see first trillionaire in next 10 years○未来10年,世界将出现第一个万亿富翁。A report says in the next ten years,the world will have its first trillionaire.The report said the wealth1 gap2?between the rich and poor is growing.And it said we will have a trillionaire within ten years,while to fight poverty,we need more than 200 years.
文摘A brand new method of automatic north seeking/sight stabilizing is introduced for usage in land fighting vehicles such as tank, etc. Some inertial devices are installed additionally on the platform along with relative control circuits to make its function of North seeking possible. Double position calculation is adopted in this method, and by alignment at two sites the azimuth angle can be figured out. Also the orientation and the horizontal shifts of the gyro are simultaneously measured and compensated so as to improve the accuracy of north seeking. The system can automatically seek north when the vehicle is immobile. And the time consumption is no more than 5.5 min. Besides, the system can keep azimuth angle and provide tilt angle and pitch angle of the vehicle.
文摘The paper described a newly developed high performance compressed air foam system(CAFS). The effective system generates uniform foam w ith greater momentum by injecting compressed air into flowing foam solution. Foa m generated by this system presented superior viscous and wetting properties to water.A pendulum system was designed to measure yield stress of foam. The results pro ved the existence of yield stress of foam. And the increasing tendency of yield stress with gas fraction and bubble size has also been found out.
