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Assessment of Used Formulae for Sonographic Estimation of Fetal Weight in Sudanese Population 被引量:1
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作者 Caroline Edward Ayad Ahmed Abdelrahim Mohammed Ibrahim +3 位作者 Mohamed Elfadil Mohamed Garelnabi Bushra Hussein Ahmed Elsafi Ahmed Abdalla Mohammed Ahmed Elshiekh Saleem 《Open Journal of Radiology》 2016年第2期113-120,共8页
The objective of this study is to assess commonly used formulae (Sheppard, Campbell, Hadlock I, II, III, and IV) for estimation of fetal weight in Sudanese population. A descriptive cross-sectional study was conducted... The objective of this study is to assess commonly used formulae (Sheppard, Campbell, Hadlock I, II, III, and IV) for estimation of fetal weight in Sudanese population. A descriptive cross-sectional study was conducted at Saudi Hospital-Khartoum-Sudan;from December 2015 to April 2016. The study included 225 singleton pregnancies. The fetal biometry—Biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL) and actual birth weights (ABW) were taken. Statistical analysis showed significant results at p ≤ 0.005. Results showed that the significant highest positive correlation between the ABW and the EFW/Kg was seen in the Hadlock I, III and IV equations having an equal values (0.951) followed by Hadlock II (0.946), Sheppard (0.872) and lastly Campbell (-0.925) with significant high degree of negative correlation. The new established equation EFW<sub>FLHCAC</sub> is the best formula identified in our study to predict Sudanese babies weight ranged between 1.86 Kg to 3.987 Kg. 展开更多
关键词 ULTRASONOGRAPHY fetal weight Gestational Age
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Fetal Thigh Circumference versus Fetal Abdominal Subcutaneous Tissue Thickness in Prediction of Fetal Weight in Term Pregnant Women
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作者 Mohamed El-Mandooh Aya Hassan Sarah Safwat 《Open Journal of Obstetrics and Gynecology》 2023年第9期1580-1594,共15页
Background: Fetal weight estimation by ultrasound is an important factor in obstetrics;it is directly related to the gestational age which helps to plan the mode of delivery and labor management. Objective: to compare... Background: Fetal weight estimation by ultrasound is an important factor in obstetrics;it is directly related to the gestational age which helps to plan the mode of delivery and labor management. Objective: to compare between fetal thigh circumference (TC) and abdominal subcutaneous tissue thickness (SCT) in estimating birthweight in term pregnant women. Patients and Methods: This prospective cohort study was conducted at outpatient clinic or emergency room, Obstetrics and Gynecology Department, Faculty of Medicine, Ain Shams University Maternity Hospitals from March 2022 until May 2023. During this study, 100 term pregnant females with gestational age 37 - 40 weeks attended El Demerdash Maternity Hospital and scheduled for delivery either at outpatient clinic or emergency room were enrolled, after consenting each of them. Basic fetal biometry was performed by an expert and professional medical personnel to ensure the accuracy of examination results. Fetal abdominal subcutaneous thickness and fetal thigh circumference were measured for assessment of gestational age and correlated with actual fetal body weight. In the current study, three formulas;Hadlock, Vintzileos’ and SCT formula were correlated with actual fetal body weight after birth. Results: The present study revealed that TC formula is closer to the actual birth weight, followed by Hadlock formula, while the SCT formula is the furthest from it. Conclusion: To increase the accuracy of birth estimations, regular ultrasound examinations should include fetal thigh circumference measurement. 展开更多
关键词 fetal Thigh Circumference fetal Abdominal Subcutaneous Thickness fetal weight Term Pregnancy
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Ultrasound estimation of fetal weight in twins by artificial neural network 被引量:2
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作者 Hanieh Mohammadi Meshkat Nemati +3 位作者 Zohreh Allahmoradi Hoda Forghani Raissi Somayeh Saraf Esmaili Ali Sheikhani 《Journal of Biomedical Science and Engineering》 2011年第1期46-50,共5页
This study was undertaken to determine the accuracy of using Ultrasound (US) estimation of twin fetuses by use of Artificial Neural Network. At First, as the training group, we performed US examinations on 186 healthy... This study was undertaken to determine the accuracy of using Ultrasound (US) estimation of twin fetuses by use of Artificial Neural Network. At First, as the training group, we performed US examinations on 186 healthy singleton fetuses within 3 days of delivery. Three input variables were used to construct the ANN model: abdominal circumference (AC), ab-dominal diameter (AD), biparietal diameter (BPD). Then, a total of 121 twin fetuses were assessed sub-sequently as the validation group. In validation group, the mean absolute error and the mean absolute per-cent error between estimated fetal weight and actual fetal weight was 261.77 g and 7.81%, respectively. Results show that, twin estimation of birth weight by ultrasound correlates fairly well with the actual weights of twin fetuses. 展开更多
关键词 ULTRASOUND fetal weight ESTIMATION TWIN Artificial Neural Network
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Predicting fetal weight by three-dimensional limb volume ultrasound (AVol/TVol) and abdominal circumference 被引量:2
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作者 Li Kang Qing-Qing Wu +2 位作者 Li-Juan Sun Feng-Yun Gao Jing-Jing Wang 《Chinese Medical Journal》 SCIE CAS CSCD 2021年第9期1070-1078,共9页
Background:Fetal weight is an important parameter to ensure maternal and child safety.The purpose of this study was to use three-dimensional(3D)limb volume ultrasound combined with fetal abdominal circumference(AC)mea... Background:Fetal weight is an important parameter to ensure maternal and child safety.The purpose of this study was to use three-dimensional(3D)limb volume ultrasound combined with fetal abdominal circumference(AC)measurement to establish a model to predict fetal weight and evaluate its efficiency.Methods:A total of 211 participants with single pregnancy(28-42 weeks)were selected between September 2017 and December 2018 in the Beijing Obstetrics and Gynecology Hospital of Capital Medical University.The upper arm(AVol)/thigh volume(TVol)of fetuses was measured by the 3D limb volume technique.Fetal AC was measured by two-dimensional ultrasound.Nine cases were excluded due to incomplete information or the interval between examination and delivery>7 days.The enrolled 202 participants were divided into a model group(134 cases,70%)and a verification group(68 cases,30%)by mechanical sampling method.The linear relationship between limb volume and fetal weight was evaluated using Pearson Chi-squared test.The prediction model formula was established by multivariate regression with data from the model group.Accuracy of the model formula was evaluated with verification group data and compared with traditional formulas(Hadlock,Lee2009,and INTERGROWTH-21st)by paired t-test and residual analysis.Receiver operating characteristic curves were generated to predict macrosomia.Results:AC,AVol,and TVol were linearly related to fetal weight.Pearson correlation coefficient was 0.866,0.862,and 0.910,respectively.The prediction model based on AVol/TVol and AC was established as follows:Y=-481.965+12.194TVol+15.358AVol+67.998AC,R2adj=0.868.The scatter plot showed that when birth weight fluctuated by 5%(i.e.,95%to 105%),the difference between the predicted fetal weight by the model and the actual weight was small.A paired t-test showed that there was no significant difference between the predicted fetal weight and the actual birth weight(t=-1.015,P=0.314).Moreover,the residual analysis showed that the model formula’s prediction efficiency was better than the traditional formulas with a mean residual of 35,360.170.The combined model of AVol/TVol and AC was superior to the Lee2009 and INTERGROWTH-21st formulas in the diagnosis of macrosomia.Its predictive sensitivity and specificity were 87.5%and 91.7%,respectively.Conclusion:Fetal weight prediction model established by semi-automatic 3D limb volume combined with AC is of high accuracy,sensitivity,and specificity.The prediction model formula shows higher predictive efficiency,especially for the diagnosis of macrosomia. 展开更多
关键词 fetal weight prediction Limb volume Three-dimensional ultrasound
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Factors Influencing the Accuracy of Sonographyestimated Fetal Weight:A Retrospective Cohort Study in the Chinese Population
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作者 Fang-Can Sun Hai-Hong Wang +6 位作者 Jing-Jing Zhang Xin-Xian Gu Ting Hu Ming-Yue Wang Yin-Di Zhu You-Guo Cheni Bing Han 《Reproductive and Developmental Medicine》 CAS CSCD 2023年第4期203-209,共7页
Objective:To evaluate the accuracy of sonography-estimated fetal weight(EFW)and to determine the potential factors influencing EFW accuracy in the Chinese population.Methods:Eleven widely used formulae were chosen to ... Objective:To evaluate the accuracy of sonography-estimated fetal weight(EFW)and to determine the potential factors influencing EFW accuracy in the Chinese population.Methods:Eleven widely used formulae were chosen to evaluate the accuracy of EFW in 7016 cases in a retrospective cohort study.Nine potential factors(prenatal body mass index[BMI],gestational age[GA],birth weight[BW],fetal sex,fetal presentation,amniotic fluid volume[AFV],seniority of sonographers,the time interval between ultrasonic measurement and delivery,and diabetes mellitus)were analyzed by binary logistic regression to determine whether they influenced sonography-EFW.Results:All 11 models had high correlation coefficients between EFW and BW(r=0.819–0.843).Model 3 was the most accurate formula for the Chinese population.Compared to fetuses with EFW of 2500–3999g,the accuracy of EFW decreased by 69.10%(P<0.001)for fetuses less than 2500g,and decreased by 54.10%(P<0.001)for fetuses larger than 4000g.The accuracy of EFW in female fetuses decreased by 12.70%compared with male fetuses(P=0.021).Compared to the EFW calculated 1-3 days before delivery,the accuracy of the EFW performed 4–7 days before delivery showed a significant decrease(P=0.014).The accuracy of EFW was influenced by the individual measurement accuracy of the sonographers.Maternal BMI,DM,GA,fetal presentation,and AFV did not influence the accuracy of EFW after adjustment.Conclusion:Model 3 was the most accurate model for the Chinese population.The BW,fetal sex,time interval,and technique of the sonographers had different influences on the accuracy of EFW. 展开更多
关键词 ACCURACY Estimated fetal weight ULTRASONOGRAPHY fetal sex Birth weight
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New Sudanese Reference Chart of Fetal Bi-ometry and Weight Using Ultrasonography
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作者 Caroline Edward Ayad Ahmed Abdelrahim Mohammed Ibrahim +3 位作者 Mohammed Elfadil Mohammed GarElnabi Bushra Hussein Ahmed Elsafi Ahmed Abdalla Mohammed Ahmed Elshiekh Saleem 《Open Journal of Radiology》 2016年第2期131-139,共9页
Background: Many centers in Sudan use the reference data for fetal biometry. The recently published population-based reference either overestimated or underestimated the weight of the fetuses. Objective: To establish ... Background: Many centers in Sudan use the reference data for fetal biometry. The recently published population-based reference either overestimated or underestimated the weight of the fetuses. Objective: To establish a national reference for fetal biometry, and weight by gestational age for singleton fetuses in Sudan. Methods: Data were collected on all singleton live births documented in the data collection sheet done at Saudi Hospital from 2015 to 2016 (n = 225). Gestational age estimation was based on the last menstrual period and fetal ultrasound thereafter. Fetal biometry and weight and other 6 fetal weight formulae were assessed. Reference data for fetal growth by gestational age were created. Results: New charts and reference equations are reported in Sudanese population for fetal biparietal diameter, head circumference, abdominal circumference and femur length and fetal weight. Conclusion: We advocate that these reference charts and equations for fetal biometry and weight might be valuable in the clinical use for appropriate ethnic Sudanese. 展开更多
关键词 fetal Biometry fetal weight Gestational Age ULTRASONOGRAPHY
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孕前BMI对孕中晚期胎儿体重生长轨迹的影响 被引量:2
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作者 李舒 孙睿洁 +7 位作者 刘亭希 张贵娟 邢仪通 陈佳佳 王淑玲 张爱红 张庆 花琳琳 《郑州大学学报(医学版)》 北大核心 2026年第1期51-55,共5页
目的:探讨孕前BMI对孕中晚期胎儿生长轨迹(FGT)的影响。方法:收集901名孕妇妊娠20~25周、26~30周、31~35周及36~40周的超声测量数据,计算估计胎儿体重(EFW)的Z评分,采用群组轨迹建模(GBTM)方法进行轨迹拟合。采用Logistic回归模型分析孕... 目的:探讨孕前BMI对孕中晚期胎儿生长轨迹(FGT)的影响。方法:收集901名孕妇妊娠20~25周、26~30周、31~35周及36~40周的超声测量数据,计算估计胎儿体重(EFW)的Z评分,采用群组轨迹建模(GBTM)方法进行轨迹拟合。采用Logistic回归模型分析孕前BMI与FGT的关联。结果:GBTM确定5种FGT,早期加速-晚期中等生长(26.19%)、晚期加速生长(19.31%)、早期加速生长(14.76%)、早期减速生长(26.97%)、迟缓生长(12.77%)。以早期加速-晚期中等生长为参照,母亲孕前BMI与早期加速生长轨迹和晚期加速生长轨迹呈正关联,OR(95%CI)分别为1.156(1.084~1.234)、1.110(1.044~1.180);与迟缓生长轨迹呈负关联,OR(95%CI)为0.910(0.840~0.987);与早期减速生长无关联,OR(95%CI)为1.034(0.975~1.096)。孕前超重肥胖母亲的胎儿出现早期加速生长和晚期加速生长的风险均升高,OR(95%CI)分别为2.268(1.406~3.659)和1.627(1.038~2.552),而孕前低体重母亲胎儿发生晚期加速生长的风险较低,OR(95%CI)为0.412(0.181~0.938)。结论:孕前BMI影响FGT;孕前超重肥胖的孕妇,其胎儿更容易出现早期或晚期加速生长。 展开更多
关键词 孕前超重肥胖 胎儿生长轨迹 估计胎儿体重
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Effect of Antenatal Depression on Fetal Growth Outcomes at the Jos University Teaching Hospital Jos, Plateau State, Nigeria
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作者 Bwatyum Annah Gyang Umar Musa +2 位作者 Agbir Terkura Michael Gyang Mark Davou Obindo James Taiwo 《Open Journal of Psychiatry》 2022年第4期336-344,共9页
Background: Depression is the most prevalent psychiatric disorder in pregnancy and it is associated with psychosocial and obstetric factors. Studies have shown that pregnancy does not prevent women from becoming depre... Background: Depression is the most prevalent psychiatric disorder in pregnancy and it is associated with psychosocial and obstetric factors. Studies have shown that pregnancy does not prevent women from becoming depressed;rather, it may be a time when depression occurs for the first time in some women. Antenatal depression has been identified as a risk factor for post natal depression, adverse obstetric outcomes, poorer neonatal outcomes and higher growth retardation in infants. Purpose: This study aimed to determine the fetal growth outcomes among depressed pregnant women in their third trimester attending antenatal clinic at the Jos University Teaching Hospital (JUTH), Jos, Plateau State, Nigeria. Method: A prospective cohort study design was used to assess 514 women who consented to the study (256 cases and 258 controls). A socio-demographic questionnaire was given to the women to fill out the study entry. Edinburgh Post Natal Depression Scale (EPDS) was used to screen for depression and MINI neuropsychiatric interviews were used to diagnose depression in those women found to be at risk of depression using the EPDS. Ultrasonography was used to determine the fetal weight in the third trimester of pregnancy. The birth weight of the babies born to the women was obtained from the birth register in the labor ward and the fetal growth rate was calculated from the estimated fetal weight on ultrasound scan in late pregnancy and the birth weight of babies. Result: The mean fetal weight in the third trimester for non-depressed women was slightly higher than in depressed women though the difference was not statistically significant (P = 0.431). The difference in the mean calculated fetal growth rate for fetuses of non-depressed women in the third trimester was statistically significantly higher than in depressed women (p = 0.000). Depressed women also had babies with lower birth weight than non-depressed women and the difference was statistically significant (p = 0.00). 展开更多
关键词 DEPRESSION Antenatal Depression fetal weight fetal Growth Rate Birth weight
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胎儿脑发育的磁共振成像研究进展
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作者 杨维新 王荣品 《磁共振成像》 北大核心 2026年第1期123-127,共5页
胎儿MRI是先进的产前影像诊断技术,它在传统解剖学检查范畴外,能对胎儿脑部及其他器官在子宫内的代谢和功能发育情况进行无创评估。随着MRI技术快速发展,胎儿MRI逐渐成为了解胎儿发育和早期辨别神经系统异常的有力方法。目前国内胎儿MR... 胎儿MRI是先进的产前影像诊断技术,它在传统解剖学检查范畴外,能对胎儿脑部及其他器官在子宫内的代谢和功能发育情况进行无创评估。随着MRI技术快速发展,胎儿MRI逐渐成为了解胎儿发育和早期辨别神经系统异常的有力方法。目前国内胎儿MRI研究主要对正常胎儿神经系统发育评估及畸形胎儿脑结构的研究,而对胎儿脑功能发育轨迹,预测出生结局及神经行为能力研究不足。本文主要利用多种MRI新技术对胎儿脑部静脉发育、代谢、微观结构和功能连接的磁共振研究进展进行综述,并指出今后研究方向。本综述将为评估正常胎儿脑发育模式、早期发现胎儿脑部发育异常提供新方法,通过观察脑部功能、代谢活动变化,发现异常代谢、神经信号,为疾病的早期诊断及出生后治疗提供依据。 展开更多
关键词 胎儿 磁共振成像 扩散加权成像 扩散张量成像 磁敏感加权成像 体素内不相干运动 磁共振波谱 静息态功能磁共振成像
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Prenatal Exposure to Polycyclic Aromatic Hydrocarbons and Birth Weight in China 被引量:2
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作者 Qiong Chen Tongzhang Zheng +13 位作者 Bryan A. Bassig Yibin Cheng Brian Leaderer Shaobin Lin Theodore Holford Jie Qiu Yawei Zhang Kunchong Shi Yong Zhu Jianjun Niu Yonghong Li Huan Guo Xiaobin Hu Yinlong Jin 《Open Journal of Air Pollution》 2014年第4期100-110,共11页
Adverse birth outcomes are a leading cause of mortality in children in China, but the environmental influences of these conditions remain largely unexplained in this population. We aimed to evaluate the levels of poly... Adverse birth outcomes are a leading cause of mortality in children in China, but the environmental influences of these conditions remain largely unexplained in this population. We aimed to evaluate the levels of polycyclic aromatic hydrocarbons (PAHs) in Chinese pregnant women and their newborns, and to examine the association between levels of PAHs and infant birth weight. We conducted a cross-sectional study including 81 pairs of mothers and newborns from four hospitals in four different cities in China. High Performance Liquid Chromatography was used to measure the concentration of nine PAHs in maternal and cord blood and multiple linear regression analyses were used to evaluate the associations of these PAHs with infant birth weight. Anthracene (ANT) had the highest average concentration and detection rate (geometric mean = 69.54 ng/g and 76.5%, respectively) in maternal serum samples, while fluoranthene (FLT) had the highest concentration and detection rate (geometric mean = 68.4 ng/g and 50.6%, respectively) in the cord blood. Most of the measured PAHs in maternal serum and three PAHs in cord blood were inversely but non-significantly associated with birth weight. The strongest associations were observed for higher concentrations of benzo (a) pyrene (BaP) in maternal serum (230.7 g decrease for levels > median vs. < LOD;p = 0.151) and for ANT in cord blood (153.1 g decrease for levels < median vs. < LOD;p = 0.208). Ant and FLT were the predominant PAHs in the maternal and cord blood serum. Serum concentrations of several measured PAHs were associated with a decreased birth weight, although not significantly, suggesting that further studies with larger sample sizes are needed to validate our findings. 展开更多
关键词 MATERNAL Exposure POLYCYCLIC Aromatic Hydrocarbon BIRTH weight fetal Development MATERNAL Serum
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基于生产性能测定的青海多胎藏羊生长曲线模型优化
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作者 张庆旭 孙武 +2 位作者 金夏阳 马世科 马玉红 《中国畜禽种业》 2026年第3期93-98,共6页
为探讨青海多胎藏羊1~6月龄生长发育规律并为其科学育种与饲养管理提供依据,选取青海省海北州海晏县高原现代生态畜牧业示范园1、3、4、5、6月龄多胎藏羊羔羊,测定体重、体高、体长、胸围四项指标,采用相关分析和多项式回归构建生长曲... 为探讨青海多胎藏羊1~6月龄生长发育规律并为其科学育种与饲养管理提供依据,选取青海省海北州海晏县高原现代生态畜牧业示范园1、3、4、5、6月龄多胎藏羊羔羊,测定体重、体高、体长、胸围四项指标,采用相关分析和多项式回归构建生长曲线模型。结果表明:各指标随月龄递增,指标间相关系数均≥0.94;以月龄、体高、体长、胸围为自变量的一阶多项式回归模型(y=–0.47+0.23A+0.08H+0.11L+0.10C)经5折交叉验证R2=0.8793,RMSE=0.98 kg,泛化能力强,可准确预测1~6月龄羔羊体重。该研究构建的生长模型可解释87.93%的体重变异,能够准确模拟青海多胎藏羊1~6月龄生长发育规律。 展开更多
关键词 青海多胎藏羊 生产性能 相关分析 生长模型 体重预测
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Outcomes of Fetal Macrosomia and Associated Factors: A Case-Control Facility Based Study
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作者 Anne Esther Njom Nlend Josepha Gwodog Arsene Brunelle Sandie 《Open Journal of Pediatrics》 CAS 2023年第2期196-206,共11页
Objective: To identify risk factors of perinatal complications among macrosomic babies in a third level health care facility. Method: We conducted a case-control institutional based study. Cases (macrosomic babies and... Objective: To identify risk factors of perinatal complications among macrosomic babies in a third level health care facility. Method: We conducted a case-control institutional based study. Cases (macrosomic babies and mothers with perinatal complications) and controls (pairs free of perinatal complication) of singleton live births were extracted from the maternity registry from January 2017 to December 2019. Matching was done for sex and gestational age after exclusion of genetic cause of macrosomia. The main primary outcome was the risk factors for complications. Logistic regression was used to estimate the odds ratio and the magnitude of association between the primary endpoint and the different covariates of the study. Results: Out of 362 couples included, we had 186 cases and 176 controls. The main perinatal complications were the delivery by caesarean section (26.5%) and lesions of the genital canal, 20.2%. There were no maternal deaths. Among newborns, metabolic complications (19.6%) were a leading cause of harmful outcomes before respiratory complications (12.4%), dystocic presentations (6.3%) or traumatic injuries (1.7%). The neonatal case fatality rate was 2.8%. Maternal age ≥30 years (p = 0.024);non-screening for gestational diabetes (p = 0.027);history of caesarean section (p = 0.041);weight gain ≥16 kg (p 0.001);maternal HIV (p = 0.047);birth weight ≥4500 g (p = 0.015) and birth height ≥52.7 ± 1.7 cm (p = 0.026) were risk factors for perinatal adverse outcomes. Conclusion: The delivery of a macrosomic baby remains problematic in this setting, and emphasizes the need to improve routine screening of gestational diabetes within a quality of prenatal follow-up through a multidisciplinary perinatal team involving obstetricians, endocrinologists and neonatal pediatricians. 展开更多
关键词 fetal Macrosomia Gestational Diabetes Maternal Obesity Birth weight fetal Growth
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小剂量阿司匹林联合低分子肝素对胎儿宫内生长受限孕妇凝血功能及胎儿发育的影响 被引量:3
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作者 袁燕 周小飞 +1 位作者 蔡波 陈德文 《天津药学》 2025年第4期471-475,共5页
目的探究小剂量阿司匹林联合低分子肝素对胎儿宫内生长受限(FGR)孕妇凝血功能及胎儿发育的影响。方法选择2021年2月至2024年4月江西省妇幼保健院收治的86例FGR孕妇,按随机数字表法分为两组,各43例。对照组予以低分子肝素,观察组采用小... 目的探究小剂量阿司匹林联合低分子肝素对胎儿宫内生长受限(FGR)孕妇凝血功能及胎儿发育的影响。方法选择2021年2月至2024年4月江西省妇幼保健院收治的86例FGR孕妇,按随机数字表法分为两组,各43例。对照组予以低分子肝素,观察组采用小剂量阿司匹林联合低分子肝素。比较两组临床疗效、凝血功能〔纤维蛋白原(FIB)、凝血酶原时间(PT)、凝血酶时间(TT)〕、胎儿发育情况〔孕妇宫高、胎儿腹围、头围、双顶径〕、胎儿血流参数〔脐动脉动力指数(PI)、阻力指数(RI)、收缩期与舒张末期血流速比(S/D)〕及不良母婴结局。结果治疗后,观察组总有效率为90.70%,高于对照组的72.09%。观察组FIB为(2.82±1.07)g/L,低于对照组的(3.73±1.31)g/L;观察组PT(9.58±1.86)s、TT(11.89±2.56)s均短于对照组的(10.75±1.47)s、(13.89±2.85)s;观察组孕妇宫高(31.52±0.49)cm、胎儿腹围(26.94±0.57)cm、头围(29.14±0.95)cm、双顶径(8.18±0.23)cm,分别大于对照组的(30.41±0.54)cm、(25.73±0.72)cm、(27.58±0.72)cm、(7.69±0.36)cm;观察组胎儿PI(1.15±0.07)、RI(0.71±0.03)、S/D(2.20±0.44)分别低于对照组的(1.19±0.09)、(0.74±0.03)、(2.73±0.59)。观察组母婴不良结局发生率为11.63%,低于对照组的32.56%,有统计学差异(P<0.05)。结论联合小剂量阿司匹林与低分子肝素对FGR疗效显著,能改善孕妇凝血功能,优化胎盘血流参数,加速胎儿生长发育,且可减少母婴不良结局的发生。 展开更多
关键词 胎儿宫内生长受限 小剂量阿司匹林 低分子肝素 凝血功能 胎儿发育
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基于胎盘体素内不相干运动MRI和胎儿脑体积预测生长受限胎儿中的极低出生体重儿
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作者 孔令男 黄世杰 +4 位作者 张璇 季亮宇 周欣 吴飞云 赵萌 《南京医科大学学报(自然科学版)》 北大核心 2025年第3期360-366,共7页
目的:探讨胎盘体素内不相干运动(intravoxel incoherent motion,IVIM)MRI参数和胎儿脑体积对FGR中VLBWI的预测价值。方法:回顾性纳入23例FGR孕妇,依据胎儿出生体重分为VLBWI组(8例)和非极低出生体重儿(non-VLBWI)组(15例)。比较两组胎... 目的:探讨胎盘体素内不相干运动(intravoxel incoherent motion,IVIM)MRI参数和胎儿脑体积对FGR中VLBWI的预测价值。方法:回顾性纳入23例FGR孕妇,依据胎儿出生体重分为VLBWI组(8例)和非极低出生体重儿(non-VLBWI)组(15例)。比较两组胎儿侧脑室占颅内体积百分比以及胎盘IVIM参数[真扩散系数(D)、伪扩散系数(D^(*))、血流灌注分数(f)及胎盘面积]。采用受试者工作特征(receiver operating characteristic,ROC)曲线分析各参数对VLBWI的预测效能。结果:VLBWI组胎盘D值小于non-VLBWI组[(1.38±0.04)×10^(-3)mm^(2)/s vs.(1.44±0.07)×10^(-3)mm^(2)/s,t=-2.109,P=0.047],胎盘面积小于non-VLBWI组[(155.84±34.69)cm^(2)vs.(200.41±47.95)cm^(2),t=-2.315,P=0.031],胎儿侧脑室占颅内体积百分比大于non-VLBWI组[(3.00±0.55)%vs.(2.53±0.33)%,t=2.591,P=0.017]。胎盘D值、胎盘面积和侧脑室占颅内体积百分比的ROC曲线下面积分别为0.767、0.783和0.792。联合胎儿侧脑室占颅内体积百分比、胎盘D值和胎盘面积可将ROC曲线下面积提高至0.892。结论:胎盘IVIM参数和胎儿脑体积可能是帮助预测FGR中VLBWI的潜在有效影像标志物。 展开更多
关键词 胎儿生长受限 极低出生体重儿 胎儿脑体积 体素内不相干运动
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三维超声测量胎盘形态学参数对早发型胎儿生长受限的诊断价值 被引量:1
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作者 唐敏敏 尹旭丹 施如勇 《浙江医学》 2025年第20期2159-2163,共5页
目的探讨三维超声测量胎盘形态学参数对高危产妇早发型胎儿生长受限(EFGR)的诊断价值。方法采用前瞻性、横断面队列观察法,选择2023年6月至2024年6月在金华市妇幼保健院正常分娩的高危孕妇(高龄、肥胖、妊娠期高血压、妊娠期糖尿病)105... 目的探讨三维超声测量胎盘形态学参数对高危产妇早发型胎儿生长受限(EFGR)的诊断价值。方法采用前瞻性、横断面队列观察法,选择2023年6月至2024年6月在金华市妇幼保健院正常分娩的高危孕妇(高龄、肥胖、妊娠期高血压、妊娠期糖尿病)105例,均为单活胎,超声检测计算孕周为13~27周。根据产后新生儿体重分为EFGR组34例和正常组71例,常规超声检测估算胎儿体重(EFW),三维超声测量胎盘形态学参数包括长度、宽度、厚度、表面积和体积,胎盘血流参数包括血管指数(VI)、血流指数(FI)和血管血流指数(VFI),上述参数与孕周的比值为标准化值。绘制ROC曲线分析胎盘形态学参数预测EFGR的效能,并计算AUC。结果与正常组相比,EFGR组EFW、标准化胎盘宽度和厚度、VI、FI和VFI的差异均无统计学意义(均P>0.05),但标准化胎盘长度、表面积、体积均明显减少(均P<0.05)。ROC曲线分析显示,标准化胎盘长度预测FGR的AUC为0.944(95%CI:0.903~0.986,P<0.001),显著高于标准化胎盘表面积和体积的AUC(均P<0.001)。标准化胎盘长度的最佳截断值为2.67,即<2.67提示有发生EFGR的风险。结论孕期应用三维超声测量胎盘形态学参数尤其是标准化胎盘长度较常规超声EFW对高危孕妇EFGR的诊断效能更佳,可作为产前诊断的新型无创性指标。 展开更多
关键词 胎儿生长受限 三维超声 胎盘形态学 估算胎儿体重 胎盘长度 胎盘血流
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基于图-文自适应加权融合的多模态胎儿辅助诊断系统
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作者 张玲 赵治栋 +3 位作者 张烨菲 焦鹏飞 邓艳军 张显飞 《中国生物医学工程学报》 北大核心 2025年第5期560-569,共10页
由于缺氧导致的窘迫或酸中毒会导致胎儿器官受损甚至死亡等不可挽回的后果。智能胎心宫缩监护(ICTG)可连续、同步记录胎心率(FHR)信号,评估胎儿状况并识别早期风险,是孕晚期监测胎儿健康的重要工具。传统的ICTG算法或聚焦于原始的FHR信... 由于缺氧导致的窘迫或酸中毒会导致胎儿器官受损甚至死亡等不可挽回的后果。智能胎心宫缩监护(ICTG)可连续、同步记录胎心率(FHR)信号,评估胎儿状况并识别早期风险,是孕晚期监测胎儿健康的重要工具。传统的ICTG算法或聚焦于原始的FHR信号特征提取,或只依据FHR的形态学参数,忽视了临床因素的影响以及不同模态数据间的互补性。本研究提出了图-文融合的胎儿辅助诊断模型(Multi-FHRNet)。根据临床生理信息结合FHR信号形态学特征构建文本模态数据,并通过马尔可夫转移场实现一维信号到二维图片的转换,构建出更为丰富的图-文双模态数据;设计两个不同的编码器:基于Vision Transformer的图片编码器与基于卷积神经网络的文本编码器,分别提取图片特征与文本特征;提出特征向量随机赋权重代替直接拼接的方法,获得多模态信息特征。经200组网络公开临床实测FHR数据,从参数优化、模型选择多角度进行了多项性能对比实验,Multi-FHRNet实现了最高达96.02%的异常识别准确率,且查准率、查全率、F1分数、曲线下面积分别为93.10%、99.29%、95.45%、93.48%,优于传统单模态算法。所提出算法可为智能化的胎儿监护实现提供理论基础和技术支撑。 展开更多
关键词 智能胎儿辅助诊断 胎心率信号 多模态学习 自适应权重 Vision Transformer(ViT)
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低分子肝素钠联合阿司匹林防治子痫前期孕妇发生胎儿生长受限的效果观察 被引量:3
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作者 李春 吴丽虾 +1 位作者 杨玲玲 吴泉锋 《中国妇幼保健》 2025年第2期209-212,共4页
目的探讨低分子肝素钠联合阿司匹林防治子痫前期孕妇发生胎儿生长受限(FGR)的效果观察。方法回顾性分析2022年1月—2023年1月厦门大学附属妇女儿童医院收治的83例子痫前期孕妇发生胎儿生长受限的临床资料。根据用药不同,分为观察组(低... 目的探讨低分子肝素钠联合阿司匹林防治子痫前期孕妇发生胎儿生长受限(FGR)的效果观察。方法回顾性分析2022年1月—2023年1月厦门大学附属妇女儿童医院收治的83例子痫前期孕妇发生胎儿生长受限的临床资料。根据用药不同,分为观察组(低分子肝素钠联合阿司匹林,40例),对照组(常规宫内营养支持治疗,43例)。比较两组患者凝血功能指标、胎儿宫内生长情况、胎儿血流动力学指标、围生儿结局及产后出血发生情况。结果相比对照组,观察组的凝血功能指标凝血酶原时间(PT)、纤维蛋白原(FIB)、D-二聚体(D-D)治疗后较治疗前改善水平均明显较高(PT 11.56±0.46 s,FIB 3.32±0.26 g/L,D-D 0.74±0.096 ng/ml),差异均有统计学意义(均P<0.05),凝血酶时间(TT)比较差异无统计学意义(P>0.05)。胎儿生长速度明显较快(双顶径5.280±0.969 mm,股骨径4.865±1.048 mm,腹围2.783±0.636 cm),差异均有统计学意义(均P<0.05)。观察组的早产(4/40,10.00%)、足月小样儿(5/40,13.90%)、新生儿窒息发生率(0/40,0.00%)明显低于对照组,差异均有统计学意义(均P<0.05)。两组在产后出血并发症的差异无统计学意义(观察组2/40,5%;对照组1/43,2.3%,P>0.05)。结论低分子肝素钠联合阿司匹林防治子痫前期孕妇发生FGR,可有效地改善凝血功能,改善胎盘循环,促进胎儿宫内生长、延长孕周、降低围生儿不良结局,并不增加产后出血并发症的发生率。 展开更多
关键词 低分子肝素钠 阿司匹林 子痫前期 胎儿生长受限
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低分子肝素对胎儿生长受限孕妇临床治疗效果及对血栓前状态的影响分析
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作者 陈小燕 《中国医药指南》 2025年第7期127-129,共3页
目的观察低分子肝素对胎儿生长受限孕妇临床治疗效果及对血栓前状态的作用。方法使用随机数字表法将2022年7月至2023年7月厦门大学附属妇女儿童医院登记胎儿生长受限孕妇56例进行分组,28例/组,对照组实施常规治疗,研究组实施常规治疗联... 目的观察低分子肝素对胎儿生长受限孕妇临床治疗效果及对血栓前状态的作用。方法使用随机数字表法将2022年7月至2023年7月厦门大学附属妇女儿童医院登记胎儿生长受限孕妇56例进行分组,28例/组,对照组实施常规治疗,研究组实施常规治疗联合低分子肝素治疗,对比两组胎儿发育指标(腹围、头围及股骨长)、脐血流指标[阻力指数(RI)、收缩末期最大血流速度/舒张末期最大血流速度(S/D)及搏动指数(PI)]及血栓指标[D-二聚体(D-D)、凝血酶时间(TT),标准化狼疮抗凝物比值(NLA)]的数值。结果两组治疗后腹围、头围及股骨长指标水平较治疗前高,且研究组以上胎儿发育指标水平较对照组高(均P<0.05)。两组治疗后RI、S/D及PI水平较治疗前低,且研究组以上脐血流指标水平较对照组低(均P<0.05)。两组治疗后D-D、NLA水平较治疗前低,TT水平较治疗前长,且研究组D-D、NLA水平低于对照组,TT长于对照组(均P<0.05)。结论低分子肝素有助于促进胎儿发育,改善脐血流,抑制血栓形成。 展开更多
关键词 胎儿生长受限 低分子肝素 血栓前状态 胎儿发育 脐血流
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低分子量肝素钠联合小剂量阿司匹林治疗胎儿生长受限的效果及对孕妇羊水指数、凝血功能的影响研究 被引量:3
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作者 王婷 刘岩 《中国实用医药》 2025年第1期15-20,共6页
目的探讨低分子量肝素钠与小剂量阿司匹林治疗胎儿生长受限的疗效及对孕妇羊水指数以及凝血功能的影响。方法以80例胎儿生长受限的孕妇为研究对象,以治疗方式不同作为孕妇分组依据,将其分为研究组(40例)、对照组(40例)。对照组孕妇采取... 目的探讨低分子量肝素钠与小剂量阿司匹林治疗胎儿生长受限的疗效及对孕妇羊水指数以及凝血功能的影响。方法以80例胎儿生长受限的孕妇为研究对象,以治疗方式不同作为孕妇分组依据,将其分为研究组(40例)、对照组(40例)。对照组孕妇采取常规治疗方式,研究组孕妇在常规治疗基础上加用低分子量肝素钠与小剂量阿司匹林联合治疗。比较两组孕妇治疗效果,胎儿生长发育情况,孕妇羊水指数与生物物理评分,孕妇凝血功能指标,胎儿脐动脉血流指标,新生儿结局。结果研究组治疗总有效率为97.50%,较对照组的80.00%更高,差异存在统计价值(P<0.05)。治疗后,两组胎儿双顶径、头围、股骨长度和腹围均较治疗前有所提升,且研究组胎儿双顶径(80.97±1.13)mm、头围(29.45±1.74)cm、股骨长度(58.23±1.01)mm和腹围(28.14±1.82)cm均明显大于对照组的(79.62±1.51)mm、(27.62±1.56)cm、(57.62±1.22)mm、(27.21±2.11)cm,差异存在统计价值(P<0.05)。治疗后,两组孕妇的羊水指数、生物物理评分均较治疗前有所提升,且研究组孕妇的羊水指数(13.82±1.35)cm、生物物理评分(9.86±0.14)分均明显比对照组的(11.85±1.44)cm、(9.53±0.22)分高,差异存在统计价值(P<0.05)。治疗后,两组孕妇的活化部分凝血活酶时间、凝血酶原时间均长于治疗前,D-二聚体和纤维蛋白原水平均低于治疗前,且研究组孕妇的活化部分凝血活酶时间(34.38±2.45)s、凝血酶原时间(13.16±3.21)s均长于对照组的(31.97±3.42)、(11.78±2.64)s,D-二聚体(0.95±0.32)mg/L和纤维蛋白原(2.89±1.03)g/L均低于对照组的(1.24±0.61)mg/L、(3.62±1.21)g/L,差异存在统计价值(P<0.05)。治疗后,两组胎儿脐动脉收缩末期与舒张末期峰值流速比值(S/D)、搏动指数(PI)以及阻力指数(RI)均较治疗前有所下降,且研究组胎儿脐动脉收缩末期与舒张末期峰值流速比值(2.34±0.41)、搏动指数(0.86±0.15)以及阻力指数(0.63±0.11)均低于对照组的(2.67±0.47)、(1.03±0.18)、(0.76±0.21),差异存在统计价值(P<0.05)。研究组早产儿1例(2.50%),足月小样儿1例(2.50%),新生儿Apgar评分为(9.23±0.44)分,新生儿出生体质量为(3.22±0.55)kg;对照组早产儿7例(17.50%),足月小样儿6例(15.00%),新生儿Apgar评分为(8.75±0.32)分,新生儿出生体质量为(2.51±0.35)kg。研究组早产儿、足月小样儿发生率均低于对照组,新生儿Apgar评分、出生体质量均高于对照组,差异存在统计价值(P<0.05)。结论小剂量阿司匹林配伍低分子量肝素钠可有效治疗胎儿生长受限,且孕妇的凝血功能得到有效改善,羊水指数也得到显著提升,实现了良好的新生儿结局,因此可被广泛用于胎儿生长受限的治疗中。 展开更多
关键词 胎儿生长受限 低分子量肝素钠 羊水指数 阿司匹林 凝血功能
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自然分娩产妇会阴裂伤发生的相关影响因素分析
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作者 张意 王银香 +1 位作者 谢菊萍 陈玲 《中国当代医药》 2025年第26期88-91,共4页
目的探讨自然分娩产妇发生会阴裂伤的相关影响因素。方法选取2023年1月至8月在赣州市妇幼保健院行自然分娩的124例产妇作为研究对象,收集、整理孕妇资料,调查自然分娩产妇会阴裂伤发生情况,并按照产妇是否发生会阴裂伤分为两组,将发生... 目的探讨自然分娩产妇发生会阴裂伤的相关影响因素。方法选取2023年1月至8月在赣州市妇幼保健院行自然分娩的124例产妇作为研究对象,收集、整理孕妇资料,调查自然分娩产妇会阴裂伤发生情况,并按照产妇是否发生会阴裂伤分为两组,将发生会阴裂伤产妇纳入为裂伤组,未发生会阴裂伤产妇纳入为非裂伤组,比较两组产妇各项资料,采用单因素分析和logistic回归分析影响自然分娩产妇会阴裂伤发生的影响因素。结果124例自然分娩产妇中发生会阴裂伤46例(37.10%),未发生会阴裂伤78例(62.90%)。单因素分析结果显示,胎儿体重、助产士年资、第二产程、会阴水肿、产次、急产、体力活动与自然分娩产妇发生会阴裂伤有关,差异有统计学意义(P<0.05)。多因素分析结果显示,胎儿体重≥4000 g(β=1.012,OR=2.750,95%CI:1.015~7.453)、助产士年资<5年(β=1.090,OR=2.975,95%CI:1.193~7.419)、第二产程长(β=1.327,OR=3.771,95%CI:1.289~11.035)、有会阴水肿(β=1.055,OR=2.871,95%CI:1.277~6.456)、初产妇(β=0.939,OR=2.557,95%CI:1.156~5.657)、急产(β=0.827,OR=2.286,95%CI:1.059~4.932)、体力活动不足(β=1.015,OR=2.760,95%CI:1.249~6.100)是自然分娩产妇发生会阴裂伤的独立危险因素(P<0.05)。结论自然分娩产妇易发生会阴裂伤,其发生与胎儿体重、助产士年资、第二产程、会阴水肿、产次、急产、体力活动等多种因素有关。 展开更多
关键词 会阴裂伤 自然分娩 会阴水肿 胎儿体重 助产士年资
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