The Ozone Monitoring Suite-Nadir(OMS-N),a state-of-the-art hyperspectral ultraviolet-visible(UV-VIS)sensor onboard China's FengYun-3F(FY-3F)satellite,was launched in August 2023.Designed for a morning orbit,OMS-N ...The Ozone Monitoring Suite-Nadir(OMS-N),a state-of-the-art hyperspectral ultraviolet-visible(UV-VIS)sensor onboard China's FengYun-3F(FY-3F)satellite,was launched in August 2023.Designed for a morning orbit,OMS-N represents a significant advancement in global atmospheric composition monitoring,offering an unprecedented spatial resolution of 7 km×7 km.The total ozone column(TOC)product derived from OMS-N is critical for climate modeling and UVradiation assessment.This study presents the first TOC retrievals from OMS-N,utilizing an adapted Differential Optical Absorption Spectroscopy(DOAS)algorithm.The retrieval algorithm overcomes traditional DOAS limitations by incorporating key innovations,including optimized radiative transfer calculations and refined a priori information on surface properties and ozone profiles,which are derived directly from OMS-N spectra rather than relying on external datasets or climatologies.Validation against ground-based measurements from Brewer,Dobson,and SAOZ instruments at 33 sites demonstrated strong agreement,with correlation coefficients mostly greater than 0.9.Comparisons with other well-established satellite instruments,including TROPOMI and GOME-2B,showed that OMS-N can consistently capture global seasonal ozone patterns,with biases typically within 2%across hemispheres and seasons.These results establish OMS-N as a reliable tool for high-resolution dynamic ozone monitoring,significantly enhancing our ability to address climate and environmental challenges.展开更多
Vestibular hair cells(HCs)in the inner ear,crucial for balance and spatial orientation,are classified into type I and type II subtypes,but the mechanisms regulating their differentiation remain unclear.In this study,w...Vestibular hair cells(HCs)in the inner ear,crucial for balance and spatial orientation,are classified into type I and type II subtypes,but the mechanisms regulating their differentiation remain unclear.In this study,we examined the role of Pou4f3,an important transcription factor,in vestibular HC differentiation using Pou4f3^(DTR/DTR)(deficient)and Pou4f3CreER/CreER(knockout)mouse models.In Pou4f3-deficient mice,the HC number decreased,and immature HCs failed to develop type I characteristics,indicating a developmental arrest.While type II HCs differentiated normally,Pou4f3 deficiency disrupted HC bundle formation and cell polarity.Findings from knockout models further confirmed the essential role of Pou4f3 in vestibular HC subtype specification.This study underscores the critical role of Pou4f3 in determining vestibular HC subtypes and offers insights into potential strategies for restoring vestibular function through HC regeneration.展开更多
Aerosol optical depth （AOD） is the most basic paxalneter that describes the optical properties of atmospheric aerosols, and it can be used to indicate aerosol content. In this study, we assimilated AOD data from the...Aerosol optical depth （AOD） is the most basic paxalneter that describes the optical properties of atmospheric aerosols, and it can be used to indicate aerosol content. In this study, we assimilated AOD data from the Fengyun-3A （FY-3A） and MODIS meteorological satellite using the Gridpoint Statistical Interpolation three-dimensional variational data assimilation system. Experiments were conducted for a dust storm over East Asia in April 2011. Each 0600 UTC analysis initialized a 24-h Weather Research and Forecasting with Chemistry model forecast. The results generally showed that the assimilation of satellite AOD observational data can significantly improve model aerosol mass prediction skills. The AOD distribution of the analysis field was closer to the observations of the satellite after assimilation of satellite AOD data. In addition, the analysis resulting from the experiment assimilating both FY-3A/MERSI （Medium-resolution Spectral Imager） AOD data and MODIS AOD data had closer agreement with the ground-based values than the individual assimilation of the two datasets for the dust storm over East Asia. These results suggest that the Chinese FY-3A satellite aerosol products can be effectively applied to numerical models and dust weather analysis.展开更多
基金supported by the National Key R&D Program of China(Grant No.2023YFB3907500)the National Natural Science Foundation of China(Grant Nos.42375142 and 42305154)+2 种基金the Open Fund of Innovation Center for FengYun Meteorological Satellite(FYSIC)FengYun Application Pioneering Project(Grant No.FY-APPZX-2022.0214)the National Civilian Space Infrastructure Project(Grant No.Y5BZ31AC60)。
文摘The Ozone Monitoring Suite-Nadir(OMS-N),a state-of-the-art hyperspectral ultraviolet-visible(UV-VIS)sensor onboard China's FengYun-3F(FY-3F)satellite,was launched in August 2023.Designed for a morning orbit,OMS-N represents a significant advancement in global atmospheric composition monitoring,offering an unprecedented spatial resolution of 7 km×7 km.The total ozone column(TOC)product derived from OMS-N is critical for climate modeling and UVradiation assessment.This study presents the first TOC retrievals from OMS-N,utilizing an adapted Differential Optical Absorption Spectroscopy(DOAS)algorithm.The retrieval algorithm overcomes traditional DOAS limitations by incorporating key innovations,including optimized radiative transfer calculations and refined a priori information on surface properties and ozone profiles,which are derived directly from OMS-N spectra rather than relying on external datasets or climatologies.Validation against ground-based measurements from Brewer,Dobson,and SAOZ instruments at 33 sites demonstrated strong agreement,with correlation coefficients mostly greater than 0.9.Comparisons with other well-established satellite instruments,including TROPOMI and GOME-2B,showed that OMS-N can consistently capture global seasonal ozone patterns,with biases typically within 2%across hemispheres and seasons.These results establish OMS-N as a reliable tool for high-resolution dynamic ozone monitoring,significantly enhancing our ability to address climate and environmental challenges.
基金supported by the National Natural Science Foundation of China(82271159,82071049,82425018,and 82101219)the STI2030-Major Projects(2022ZD0205400).
文摘Vestibular hair cells(HCs)in the inner ear,crucial for balance and spatial orientation,are classified into type I and type II subtypes,but the mechanisms regulating their differentiation remain unclear.In this study,we examined the role of Pou4f3,an important transcription factor,in vestibular HC differentiation using Pou4f3^(DTR/DTR)(deficient)and Pou4f3CreER/CreER(knockout)mouse models.In Pou4f3-deficient mice,the HC number decreased,and immature HCs failed to develop type I characteristics,indicating a developmental arrest.While type II HCs differentiated normally,Pou4f3 deficiency disrupted HC bundle formation and cell polarity.Findings from knockout models further confirmed the essential role of Pou4f3 in vestibular HC subtype specification.This study underscores the critical role of Pou4f3 in determining vestibular HC subtypes and offers insights into potential strategies for restoring vestibular function through HC regeneration.
基金supported by the National Key Research and Development Program of China (Grant Nos.2017YFC1502100 and 2016YFA0602302)the Natural Science Foundation of Jiangsu Province (Grant Nos.BK20160954 and BK20170940)+3 种基金the Beijige Funding from Jiangsu Research Institute of Meteorological Science (Grant Nos.BJG201510 and BJG201604)the Startup Foundation for Introducing Talent of NUIST (Grant Nos.2016r27,2016r043 and 2017r058)a project for data application of Fengyun3 meteorological satellite [FY-3(02)UDS-1.1.2]the Priority Academic Program Development of Jiangsu Higher Education Institutions
文摘Aerosol optical depth （AOD） is the most basic paxalneter that describes the optical properties of atmospheric aerosols, and it can be used to indicate aerosol content. In this study, we assimilated AOD data from the Fengyun-3A （FY-3A） and MODIS meteorological satellite using the Gridpoint Statistical Interpolation three-dimensional variational data assimilation system. Experiments were conducted for a dust storm over East Asia in April 2011. Each 0600 UTC analysis initialized a 24-h Weather Research and Forecasting with Chemistry model forecast. The results generally showed that the assimilation of satellite AOD observational data can significantly improve model aerosol mass prediction skills. The AOD distribution of the analysis field was closer to the observations of the satellite after assimilation of satellite AOD data. In addition, the analysis resulting from the experiment assimilating both FY-3A/MERSI （Medium-resolution Spectral Imager） AOD data and MODIS AOD data had closer agreement with the ground-based values than the individual assimilation of the two datasets for the dust storm over East Asia. These results suggest that the Chinese FY-3A satellite aerosol products can be effectively applied to numerical models and dust weather analysis.
