AIM:To investigate the clinical features and prognosis of patients with orbital inflammatory myofibroblastic tumor(IMT).METHODS:This retrospective study collected clinical data from 22 patients diagnosed with orbital ...AIM:To investigate the clinical features and prognosis of patients with orbital inflammatory myofibroblastic tumor(IMT).METHODS:This retrospective study collected clinical data from 22 patients diagnosed with orbital IMT based on histopathological examination.The patients were followed up to assess their prognosis.Clinical data from patients,including age,gender,course of disease,past medical history,primary symptoms,ophthalmologic examination findings,general condition,as well as imaging,laboratory,histopathological,and immunohistochemical results from digital records were collected.Orbital magnetic resonance imaging(MRI)and(or)computed tomography(CT)scans were performed to assess bone destruction of the mass,invasion of surrounding tissues,and any inflammatory changes in periorbital areas.RESULTS:The mean age of patients with orbital IMT was 28.24±3.30y,with a male-to-female ratio of 1.2:1.Main clinical manifestations were proptosis,blurred vision,palpable mass,and pain.Bone destruction and surrounding tissue invasion occurred in 72.73%and 54.55%of cases,respectively.Inflammatory changes in the periorbital site were observed in 77.27%of the patients.Hematoxylin and eosin staining showed proliferation of fibroblasts and myofibroblasts,accompanied by infiltration of lymphocytes and plasma cells.Immunohistochemical staining revealed that smooth muscle actin(SMA)and vimentin were positive in 100%of cases,while anaplastic lymphoma kinase(ALK)showed positivity in 47.37%.The recurrence rate of orbital IMT was 27.27%,and sarcomatous degeneration could occur.There were no significant correlations between recurrence and factors such as age,gender,laterality,duration of the disease,periorbital tissue invasion,bone destruction,periorbital inflammation,tumor size,fever,leukocytosis,or treatment(P>0.05).However,lymphadenopathy and a Ki-67 index of 10%or higher may be risk factors for recurrence(P=0.046;P=0.023).CONCLUSION:Orbital IMT is a locally invasive disease that may recur or lead to sarcomatoid degeneration,primarily affecting young and middle-aged patients.The presence of lymphadenopathy and a Ki-67 index of 10%or higher may signify a poor prognosis.展开更多
In the field of intelligent air combat,real-time and accurate recognition of within-visual-range(WVR)maneuver actions serves as the foundational cornerstone for constructing autonomous decision-making systems.However,...In the field of intelligent air combat,real-time and accurate recognition of within-visual-range(WVR)maneuver actions serves as the foundational cornerstone for constructing autonomous decision-making systems.However,existing methods face two major challenges:traditional feature engineering suffers from insufficient effective dimensionality in the feature space due to kinematic coupling,making it difficult to distinguish essential differences between maneuvers,while end-to-end deep learning models lack controllability in implicit feature learning and fail to model high-order long-range temporal dependencies.This paper proposes a trajectory feature pre-extraction method based on a Long-range Masked Autoencoder(LMAE),incorporating three key innovations:(1)Random Fragment High-ratio Masking(RFH-Mask),which enforces the model to learn long-range temporal correlations by masking 80%of trajectory data while retaining continuous fragments;(2)Kalman Filter-Guided Objective Function(KFG-OF),integrating trajectory continuity constraints to align the feature space with kinematic principles;and(3)Two-stage Decoupled Architecture,enabling efficient and controllable feature learning through unsupervised pre-training and frozen-feature transfer.Experimental results demonstrate that LMAE significantly improves the average recognition accuracy for 20-class maneuvers compared to traditional end-to-end models,while significantly accelerating convergence speed.The contributions of this work lie in:introducing high-masking-rate autoencoders into low-informationdensity trajectory analysis,proposing a feature engineering framework with enhanced controllability and efficiency,and providing a novel technical pathway for intelligent air combat decision-making systems.展开更多
In July 2021,a catastrophic extreme precipitation(EP)event occurred in Henan Province,China,resulting in considerable human and economic losses.The synoptic pattern during this event is distinctive,characterized by th...In July 2021,a catastrophic extreme precipitation(EP)event occurred in Henan Province,China,resulting in considerable human and economic losses.The synoptic pattern during this event is distinctive,characterized by the presence of two typhoons and substantial water transport into Henan.However,a favorable synoptic pattern only does not guarantee the occurrence of heavy precipitation in Henan.This study investigates the key environmental features critical for EP under similar synoptic patterns to the 2021 Henan extreme event.It is found that cold clouds are better aggregated on EP days,accompanied by beneficial environment features like enhanced moisture conditions,stronger updrafts,and greater atmospheric instability.The temporal evolution of these environmental features shows a leading signal by one to three days.These results suggest the importance of combining the synoptic pattern and environmental features in the forecasting of heavy precipitation events.展开更多
AIM:To investigate the potential mechanisms of A-V pattern and evaluate the surgical outcomes used in the treatment of sensory exotropia.METHODS:The medical records of patients with sensory A-V pattern exotropia who u...AIM:To investigate the potential mechanisms of A-V pattern and evaluate the surgical outcomes used in the treatment of sensory exotropia.METHODS:The medical records of patients with sensory A-V pattern exotropia who underwent strabismus surgery between May 2014 to June 2019 was retrospectively reviewed.The control group included sensory exotropia patients without A-V pattern and concomitant A-V pattern exotropia patients with normal vision who undergone strabismus surgery over this same time period.Ocular alignment,best corrected visual acuity,oblique muscle function,and stereopsis records were collected.RESULTS:Among the 843 eligible patients,91(10.79%;39 males and 52 females)had A-pattern(54,6.4%)or V-pattern(37,4.4%).Age at onset of vision impairment was 4±5y and at the time of surgery was 25±9y.Statistically significant negative correlations were present between impaired visual acuity and the pre-operative exodeviation(r=-0.198,P=0.016)and patterns(r=-0.207,P=0.015).Age at surgery and exodeviation in patients with concomitant A-V pattern exotropia was significantly earlier as compared with that of sensory A-V pattern exotropia and sensory exotropia(both P<0.0001).There were no significant differences in these clinical variables between sensory exotropia with or without A-V pattern.Deviation and pattern were significantly reduced in patients receiving horizontal rectus surgery with or without oblique muscle surgery(both P<0.0001).CONCLUSION:The prevalence of sensory A-V pattern exotropia in our study is 10.79%.Visual acuity represents an important factor contributing to the occurrence and development of A-V pattern.Isolated horizontal rectus surgery can provide a good option for the correction of sensory A-V pattern exotropia.展开更多
The Sichuan Basin(SCB),China has a high incidence of extremely persistent heavy rainfall(EPHR)events.The EPHR events from 2009 to 2019 in the SCB were mainly concentrated over the northern and northwestern windward sl...The Sichuan Basin(SCB),China has a high incidence of extremely persistent heavy rainfall(EPHR)events.The EPHR events from 2009 to 2019 in the SCB were mainly concentrated over the northern and northwestern windward slopes and the central basin.They occurred from June to September,but especially in July,and peaked at 0300 LST.ERA5 reanalysis data and objective classification were used to investigate the synoptic patterns and their effects.There were three synoptic patterns during EPHR events,all accompanied by a Southwest Vortex.The location and intensity of the Southwest Vortex,thermal forcing of the Tibetan Plateau(TP),and low-level winds can greatly affect the intensity and spatial distribution of EPHR.When the Southwest Vortex was located in the western SCB and there were southerly low-level jets(LLJs),convergence and upslope wind would lead to EPHR over the northwestern or northern windward slopes.If there was no LLJ and the whole SCB was under the center of the Southwest Vortex,nocturnal EPHR was controlled by the internal circulation of the Southwest Vortex and the updraft generated by the thermal forcing of the TP,and the rainfall was weaker.The southeastern entrance of the SCB was a key area where the low-level wind dominated the nocturnal peak of EPHR.The nocturnal strengthened southeasterly wind in the key area is attributable to inertial oscillation,and the topographic friction plays an essential role in transporting momentum and moisture into the basin by generating easterly and northeasterly ageostrophic winds.展开更多
BACKGROUND The microcystic,elongated,and fragmented(MELF)pattern of invasion in endometrioid endometrial carcinoma(EEC)is a special mode of myometrial invasion that has been recently recognized by the pathology commun...BACKGROUND The microcystic,elongated,and fragmented(MELF)pattern of invasion in endometrioid endometrial carcinoma(EEC)is a special mode of myometrial invasion that has been recently recognized by the pathology community.Overex-pression of CXC chemokine receptor 4(CXCR4)in tumor cells contributes to tumor growth,invasion,angiogenesis,metastasis,and recurrence.AIM To explore the correlation between CXCR4 expression in EEC and MELF invasion and clinicopathological features.METHODS A total of 205 EEC patients treated at Peking University People’s Hospital from June 2020 to December 2021 were selected(60 cases with MELF invasion,145 cases without).The clinicopathological features of the two groups were compared,and expression of CXCR4 protein,estrogen receptor,and progesterone receptor was detected and compared by immunohistochemistry.RESULTS EEC with MELF invasion was significantly associated with low tumor grade,lymphovascular space invasion,deep myometrial invasion,cervical stromal involvement,and lymph node metastasis.There was a difference in CXCR4 expression between the two groups,with the MELF group having a significantly higher expression than the non-MELF group.CONCLUSION CXCR4 expression is significantly increased in EEC with MELF invasion and in the MELF invasion area,which may promote tumor invasion and metastasis and has some value for prognostic assessment.展开更多
Fractal theory is becoming an increasingly useful tool to describe soil structure dynamics for a better understanding of the performance of soil systems. Changes in land use patterns significantly affect soil physical...Fractal theory is becoming an increasingly useful tool to describe soil structure dynamics for a better understanding of the performance of soil systems. Changes in land use patterns significantly affect soil physical, chemical and biological properties. However, limited information is available on the fractal characteristics of deep soil layers under different land use patterns. In this study, the fractal dimensions of particle size distribution（PSD） and micro-aggregates in the 0–500 cm soil profile and soil anti-erodibility in the 0–10 cm soil profile for 10 typical land use patterns were investigated in the Zhifanggou Watershed on the Loess Plateau, China. The 10 typical land use patterns were： slope cropland, two terraced croplands, check-dam cropland, woodland, two shrublands, orchard, artificial and natural grasslands. The results showed that the fractal dimensions of PSD and micro-aggregates were all significantly influenced by soil depths, land use patterns and their interaction. The plantations of shrubland, woodland and natural grassland increased the amount of larger micro-aggregates, and decreased the fractal dimensions of micro-aggregates in the 0–40 cm soil profile. And they also improved the aggregate state and aggregate degree and decreased dispersion rate in the 0–10 cm soil profile. The results indicated that fractal theory can be used to characterize soil structure under different land use patterns and fractal dimensions of micro-aggregates were more effective in this regard. The natural grassland may be the best choice for improving soil structure in the study area.展开更多
BACKGROUND Different histological growth patterns(HGPs)of colorectal carcinoma(CRC)liver metastasis are associated with patients’prognosis and response to antiangiogenic therapy.However,the relationship between HGPs ...BACKGROUND Different histological growth patterns(HGPs)of colorectal carcinoma(CRC)liver metastasis are associated with patients’prognosis and response to antiangiogenic therapy.However,the relationship between HGPs of liver metastasis and clinicopathological and genomic characteristics of primary cancer has not been well established.AIM To assess whether certain clinicopathological and genomic features of primary CRC could predict the HGPs of liver metastasis.METHODS A total of 29 patients with paired resections of both primary CRC and liver metastasis were divided into two groups:A(15 cases with desmoplastic liver metastasis)and B(14 cases with replacement liver metastasis).Clinical information was obtained from patients’charts.Mismatch repair proteins,BRAFV600E,and PD-L1 were evaluated by immunohistochemistry.Five cases were selected randomly from each group for whole exome sequencing(WES)analysis.RESULTS In the primary tumor,expanding growth pattern,low tumor budding score(TBS),and Crohn’s disease-like response(CDR)were associated with desmoplastic liver metastasis and better overall survival,whereas infiltrating growth pattern alone of primary carcinoma could predict the replacement liver metastasis and worse overall survival(P<0.05).On WES analysis,primary carcinoma with desmoplastic liver metastasis showed mutations in APC(4/5);TP53(3/5);KRAS,PIK3CA,and FAT4(2/5);BRCA-1,BRCA2,BRAF,and DNAH5(1/5),whereas primary carcinoma with replacement liver metastasis showed mutations in APC and TP53(3/5);KRAS,FAT4,DNH5,SMAD,ERBB2,ERBB3,LRP1,and SDK1(1/5).CONCLUSION The HGPs,TBS,and CDR of primary CRC as well as the presence of specific genetic mutations such as those in PIK3CA could be used to predict the HGPs of liver metastasis,response to therapy,and patients’prognosis.展开更多
Recent exploration results indicate that a significant exploration potential remains in the Dongying Depression of the Bohai Bay Basin and the undiscovered oil and gas are largely reservoired in subtle traps including...Recent exploration results indicate that a significant exploration potential remains in the Dongying Depression of the Bohai Bay Basin and the undiscovered oil and gas are largely reservoired in subtle traps including turbidite litholigcal traps of the Sha-3 Member. In order to effectively guide the exploration program targeting turbidites, this study will focus on the depositional models of the Sha-3 Member turbidites and oil/gas accumulation characteristics in these turbidites. Two corresponding relationships were found. One is that the East African Rift Valley provides a modern analog for the depositional systems in the Dongying Depression. The other is that the depositional models of line-sourced slope aprons, single point-source submarine fan and multiple source ramp turbidite, established for deep-sea turbidites, can be applied to interpret the depositional features of the turbidite fans of three different origins: slope turbidite aprons, lake floor turbidite fans and delta-fed turbidite fans in the Sha-3 Member. Updip sealing integrity is the key factor determining whether oil/gas accumulates or not in the slope aprons and lake floor fans. The factors controlling oil/gas migration and accumulation in the delta-fed turbidite fans are not very clear. Multiple factors rather than a single factor probably played significant roles in these processes.展开更多
In this paper, three types of weld flaw were taken as target, evaluation and recognition of flaw echo features were studied. On the basis of experimental study and theoretical analysis, 26 features have been extracted...In this paper, three types of weld flaw were taken as target, evaluation and recognition of flaw echo features were studied. On the basis of experimental study and theoretical analysis, 26 features have been extracted from each echo samples. A method which is based on the xtatislical hypothesis testing and used for feature evaluation and optimum subset selection was explored. Thus, the dimensionality reduction of feature space was brought out, and simultaneously the amount of calculation was decreased. An intelligent pattern classifier with B-P type neural network was constructed which was characterized by high speed and accuracy for learning. Using a half of total samples as training set and others as testing set, the learning efficiency and the classification ability of network model were studied. The results of experiment showed that the learning rate of different training samples was about 100%. The results of recognition was satisfactory when the optimum feature subset was taken as the sample's feature vectors. The average recognition rate of three type flaws was about 87.6%, and the best recognition rate amounted to 97%.展开更多
In this study, we determine differences in total biomass of soil microorganisms and community structure (using the most probable number of bacteria (MPN) and the number of fungal genera) in patterned ground features (...In this study, we determine differences in total biomass of soil microorganisms and community structure (using the most probable number of bacteria (MPN) and the number of fungal genera) in patterned ground features (PGF) and adjacent vegetated soils (AVS) in mesic sites from three High Arctic islands in order to characterize microbial dynamics as affected by cryoturbation, and a broad bioclimatic gradient. We also characterize total biomass of soil microorganisms and the most probable number of bacteria along a topographic gradient within each bioclimatic subzone to evaluate whether differences in topography lead to differences in microbial dynamics at a smaller scale. We found total microbial biomass C, the most probable number of heterotrophic bacteria, and fungal genera vary along this bioclimatic gradient. Microbial biomass C decreased with increasing latitude. Overall, microbial biomass C, MPN and the number of fungal isolates were higher in AVS than in PGFs. The effects which topographic position had on microbial biomass C varied across the bioclimatic gradient as there was no effect of topographic position in Isachsen (subzone A) and Mould Bay (subzone B), when compared to Green Cabin (subzone C, warmer site).There was no effect of topographic position on MPN counts at Mould Bay and Green Cabin. However, in Isachsen, MPN counts were highest in the wet topographic position as compared to the mesic and dry. In conclusion, PGFs seem to decouple the effect climate that might have on the total biomass of soil microorganisms along the bioclimatic gradient;and influence gets ameliorated as latitude increases. Similarly, the effect of topography on the total microbial biomass is significant at the warmest bioclimatic zone of the gradient. Thus, climate and topographic effects on total microbial biomass increase with warmer climate.展开更多
In this paper we used two new features i.e. T-wave integral and total integral as extracted feature from one cycle of normal and patient ECG signals to detection and localization of myocardial infarction (MI) in left ...In this paper we used two new features i.e. T-wave integral and total integral as extracted feature from one cycle of normal and patient ECG signals to detection and localization of myocardial infarction (MI) in left ventricle of heart. In our previous work we used some features of body surface potential map data for this aim. But we know the standard ECG is more popular, so we focused our detection and localization of MI on standard ECG. We use the T-wave integral because this feature is important impression of T-wave in MI. The second feature in this research is total integral of one ECG cycle, because we believe that the MI affects the morphology of the ECG signal which leads to total integral changes. We used some pattern recognition method such as Artificial Neural Network (ANN) to detect and localize the MI, because this method has very good accuracy for classification of normal signal and abnormal signal. We used one type of Radial Basis Function (RBF) that called Probabilistic Neural Network (PNN) because of its nonlinearity property, and used other classifier such as k-Nearest Neighbors (KNN), Multilayer Perceptron (MLP) and Naive Bayes Classification. We used PhysioNet database as our training and test data. We reached over 76% for accuracy in test data for localization and over 94% for detection of MI. Main advantages of our method are simplicity and its good accuracy. Also we can improve the accuracy of classification by adding more features in this method. A simple method based on using only two features which were extracted from standard ECG is presented and has good accuracy in MI localization.展开更多
Five-electrode configurations were designed to simulate the distribution inhomogeneity of electric field intensities in the air-insulating medium, and the characteristic data waveforms of partial discharge generated b...Five-electrode configurations were designed to simulate the distribution inhomogeneity of electric field intensities in the air-insulating medium, and the characteristic data waveforms of partial discharge generated by different electrode configurations under the excitation of power frequency AC voltage were carefully collected in this paper. Furthermore, the feature vectors of the corresponding fingerprint, contained in partial discharge data, were extracted by rigorous mathematical algorithms, and the artificial neural network was employed to realize the pattern recognition of partial discharge caused by the inhomogeneity of electric field intensity with different electrode configurations. The results indicate that the J<sub>4</sub> value in the space of 7 feature quantities is 1905.6, and the recognition rate is 100% when the hidden layer neuron of the network is 19. However, the J<sub>5</sub> value of 9 feature quantities is 1589.9, and the purpose of recognition has been achieved when the number of hidden layer neurons of the network is 6. Increasing the number of hidden layer neurons will only waste computing resources. Of course, PD information collection mode, feature quantity selection, optimal feature space composition, network structure and classification algorithm are the key to realizing PD fault intelligence identification.展开更多
In the article“A Lightweight Approach for Skin Lesion Detection through Optimal Features Fusion”by Khadija Manzoor,Fiaz Majeed,Ansar Siddique,Talha Meraj,Hafiz Tayyab Rauf,Mohammed A.El-Meligy,Mohamed Sharaf,Abd Ela...In the article“A Lightweight Approach for Skin Lesion Detection through Optimal Features Fusion”by Khadija Manzoor,Fiaz Majeed,Ansar Siddique,Talha Meraj,Hafiz Tayyab Rauf,Mohammed A.El-Meligy,Mohamed Sharaf,Abd Elatty E.Abd Elgawad Computers,Materials&Continua,2022,Vol.70,No.1,pp.1617–1630.DOI:10.32604/cmc.2022.018621,URL:https://www.techscience.com/cmc/v70n1/44361,there was an error regarding the affiliation for the author Hafiz Tayyab Rauf.Instead of“Centre for Smart Systems,AI and Cybersecurity,Staffordshire University,Stoke-on-Trent,UK”,the affiliation should be“Independent Researcher,Bradford,BD80HS,UK”.展开更多
Two field studies were conducted to measure pigments in the Southern Yellow Sea (SYS) and the northern East China Sea (NECS) in April (spring) and September (autumn) to evaluate the distribution pattern of phytoplankt...Two field studies were conducted to measure pigments in the Southern Yellow Sea (SYS) and the northern East China Sea (NECS) in April (spring) and September (autumn) to evaluate the distribution pattern of phytoplankton stock (Chl a concentration) and the impact of hydrological features such as water mass,mixing and tidal front on these patterns.The results indicated that the Chl a concentration was 2.43±2.64 (Mean ± SD) mg m-3 in April (range,0.35 to 17.02 mg m-3) and 1.75±3.10 mg m-3 in September (from 0.07 to 36.54 mg m-3) in 2003.Additionally,four areas with higher Chl a concentrations were observed in the surface water in April,while two were observed in September,and these areas were located within or near the point at which different water masses converged (temperature front area).The distribution pattern of Chl a was generally consistent between onshore and offshore stations at different depths in April and September.Specifically,higher Chl a concentrations were observed along the coastal line in September,which consisted of a mixing area and a tidal front area,although the distributional pattern of Chl a concentrations varied along transects in April.The maximum Chl a concentration at each station was observed in the surface and subsurface layer (0-10 m) for onshore stations and the thermocline layer (10-30 m) for offshore stations in September,while the greatest concentrations were generally observed in surface and subsurface water (0-10 m) in April.The formation of the Chl a distributional pattern in the SYS and NECS and its relationship with possible influencing factors is also discussed.Although physical forces had a close relationship with Chl a distribution,more data are required to clearly and comprehensively elucidate the spatial pattern dynamics of Chl a in the SYS and NECS.展开更多
The molecular network features of spinal cord development that are integral to tissue engineering remain poorly understood in placental mammals,especially in terms of their relationships with vital biological processe...The molecular network features of spinal cord development that are integral to tissue engineering remain poorly understood in placental mammals,especially in terms of their relationships with vital biological processes such as regeneration.Here,using a large-scale temporal transcriptomic analysis of rat spinal cord from the embryonic stage to adulthood,we show that fluctuating RNA expression levels reflect highly active transcriptional regulation,which may initiate spinal cord patterning.We also demonstrate that microRNAs(miRNAs)and transcriptional factors exhibit a mosaic profile based on their expression patterns,while differential alternative splicing events reveal that alternative splicing may be a driving force for the development of the node of Ranvier.Our study also supports the existence of a negative correlation between innate immunity and intrinsic growth capacity.Epigenetic modifications appear to perform their respective regulatory functions at different stages of development,while guanine nucleotidebinding protein(G protein)-coupled receptors(including olfactory receptors(ORs))may perform pleiotropic roles in axonal growth.This study provides a valuable resource for investigating spinal cord development and complements the increasing number of single-cell datasets.These findings also provide a genetic basis for the development of novel tissue engineering strategies.展开更多
The results of a theoretical study on the influence of strength of interphase boundaries in metal-ceramic composite on macroscopical characteristics of composite response such as strength, deformation capacity, fractu...The results of a theoretical study on the influence of strength of interphase boundaries in metal-ceramic composite on macroscopical characteristics of composite response such as strength, deformation capacity, fracture energy and fracture pattern are presented. The study was conducted by means of computer-aided simulation by means of movable cellular automaton method taking account of a developed ＂mesoscopical＂ structural model of particle-reinforced composite. The strength of interphase boundaries is found to be a key structural factor determining not only the strength properties of metal-ceramic composite, but also the pattern and rate of fracture. The principles for achievement of the high-strength values of particle/binder interfaces in the metal-ceramic composition due to the formation of the wide transition zones （areas of variable chemical composition） at the interphase boundaries are discussed. Simulation results confirm that such transition zones provide a change in fracture mechanism and make the achievement of a high-strength and a high deformation capacity of metal-ceramic composite possible.展开更多
BACKGROUND Pancreatic cancer remains one of the most lethal malignancies worldwide,with a poor prognosis often attributed to late diagnosis.Understanding the correlation between pathological type and imaging features ...BACKGROUND Pancreatic cancer remains one of the most lethal malignancies worldwide,with a poor prognosis often attributed to late diagnosis.Understanding the correlation between pathological type and imaging features is crucial for early detection and appropriate treatment planning.AIM To retrospectively analyze the relationship between different pathological types of pancreatic cancer and their corresponding imaging features.METHODS We retrospectively analyzed the data of 500 patients diagnosed with pancreatic cancer between January 2010 and December 2020 at our institution.Pathological types were determined by histopathological examination of the surgical spe-cimens or biopsy samples.The imaging features were assessed using computed tomography,magnetic resonance imaging,and endoscopic ultrasound.Statistical analyses were performed to identify significant associations between pathological types and specific imaging characteristics.RESULTS There were 320(64%)cases of pancreatic ductal adenocarcinoma,75(15%)of intraductal papillary mucinous neoplasms,50(10%)of neuroendocrine tumors,and 55(11%)of other rare types.Distinct imaging features were identified in each pathological type.Pancreatic ductal adenocarcinoma typically presents as a hypodense mass with poorly defined borders on computed tomography,whereas intraductal papillary mucinous neoplasms present as characteristic cystic lesions with mural nodules.Neuroendocrine tumors often appear as hypervascular lesions in contrast-enhanced imaging.Statistical analysis revealed significant correlations between specific imaging features and pathological types(P<0.001).CONCLUSION This study demonstrated a strong association between the pathological types of pancreatic cancer and imaging features.These findings can enhance the accuracy of noninvasive diagnosis and guide personalized treatment approaches.展开更多
During Donald Trump’s first term,the“Trump Shock”brought world politics into an era of uncertainties and pulled the transatlantic alliance down to its lowest point in history.The Trump 2.0 tsunami brewed by the 202...During Donald Trump’s first term,the“Trump Shock”brought world politics into an era of uncertainties and pulled the transatlantic alliance down to its lowest point in history.The Trump 2.0 tsunami brewed by the 2024 presidential election of the United States has plunged the U.S.-Europe relations into more gloomy waters,ushering in a more complex and turbulent period of adjustment.展开更多
基金Supported by the National Key R&D Program of China(No.2023YFC2410203)Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support(No.ZLRK202503).
文摘AIM:To investigate the clinical features and prognosis of patients with orbital inflammatory myofibroblastic tumor(IMT).METHODS:This retrospective study collected clinical data from 22 patients diagnosed with orbital IMT based on histopathological examination.The patients were followed up to assess their prognosis.Clinical data from patients,including age,gender,course of disease,past medical history,primary symptoms,ophthalmologic examination findings,general condition,as well as imaging,laboratory,histopathological,and immunohistochemical results from digital records were collected.Orbital magnetic resonance imaging(MRI)and(or)computed tomography(CT)scans were performed to assess bone destruction of the mass,invasion of surrounding tissues,and any inflammatory changes in periorbital areas.RESULTS:The mean age of patients with orbital IMT was 28.24±3.30y,with a male-to-female ratio of 1.2:1.Main clinical manifestations were proptosis,blurred vision,palpable mass,and pain.Bone destruction and surrounding tissue invasion occurred in 72.73%and 54.55%of cases,respectively.Inflammatory changes in the periorbital site were observed in 77.27%of the patients.Hematoxylin and eosin staining showed proliferation of fibroblasts and myofibroblasts,accompanied by infiltration of lymphocytes and plasma cells.Immunohistochemical staining revealed that smooth muscle actin(SMA)and vimentin were positive in 100%of cases,while anaplastic lymphoma kinase(ALK)showed positivity in 47.37%.The recurrence rate of orbital IMT was 27.27%,and sarcomatous degeneration could occur.There were no significant correlations between recurrence and factors such as age,gender,laterality,duration of the disease,periorbital tissue invasion,bone destruction,periorbital inflammation,tumor size,fever,leukocytosis,or treatment(P>0.05).However,lymphadenopathy and a Ki-67 index of 10%or higher may be risk factors for recurrence(P=0.046;P=0.023).CONCLUSION:Orbital IMT is a locally invasive disease that may recur or lead to sarcomatoid degeneration,primarily affecting young and middle-aged patients.The presence of lymphadenopathy and a Ki-67 index of 10%or higher may signify a poor prognosis.
文摘In the field of intelligent air combat,real-time and accurate recognition of within-visual-range(WVR)maneuver actions serves as the foundational cornerstone for constructing autonomous decision-making systems.However,existing methods face two major challenges:traditional feature engineering suffers from insufficient effective dimensionality in the feature space due to kinematic coupling,making it difficult to distinguish essential differences between maneuvers,while end-to-end deep learning models lack controllability in implicit feature learning and fail to model high-order long-range temporal dependencies.This paper proposes a trajectory feature pre-extraction method based on a Long-range Masked Autoencoder(LMAE),incorporating three key innovations:(1)Random Fragment High-ratio Masking(RFH-Mask),which enforces the model to learn long-range temporal correlations by masking 80%of trajectory data while retaining continuous fragments;(2)Kalman Filter-Guided Objective Function(KFG-OF),integrating trajectory continuity constraints to align the feature space with kinematic principles;and(3)Two-stage Decoupled Architecture,enabling efficient and controllable feature learning through unsupervised pre-training and frozen-feature transfer.Experimental results demonstrate that LMAE significantly improves the average recognition accuracy for 20-class maneuvers compared to traditional end-to-end models,while significantly accelerating convergence speed.The contributions of this work lie in:introducing high-masking-rate autoencoders into low-informationdensity trajectory analysis,proposing a feature engineering framework with enhanced controllability and efficiency,and providing a novel technical pathway for intelligent air combat decision-making systems.
基金supported by the National Key Research and Development Pro-gram of China(Grant No.2022YFC3003902)the National Natu-ral Science Foundation of China(Grant Nos.42075146 and 42275006).
文摘In July 2021,a catastrophic extreme precipitation(EP)event occurred in Henan Province,China,resulting in considerable human and economic losses.The synoptic pattern during this event is distinctive,characterized by the presence of two typhoons and substantial water transport into Henan.However,a favorable synoptic pattern only does not guarantee the occurrence of heavy precipitation in Henan.This study investigates the key environmental features critical for EP under similar synoptic patterns to the 2021 Henan extreme event.It is found that cold clouds are better aggregated on EP days,accompanied by beneficial environment features like enhanced moisture conditions,stronger updrafts,and greater atmospheric instability.The temporal evolution of these environmental features shows a leading signal by one to three days.These results suggest the importance of combining the synoptic pattern and environmental features in the forecasting of heavy precipitation events.
文摘AIM:To investigate the potential mechanisms of A-V pattern and evaluate the surgical outcomes used in the treatment of sensory exotropia.METHODS:The medical records of patients with sensory A-V pattern exotropia who underwent strabismus surgery between May 2014 to June 2019 was retrospectively reviewed.The control group included sensory exotropia patients without A-V pattern and concomitant A-V pattern exotropia patients with normal vision who undergone strabismus surgery over this same time period.Ocular alignment,best corrected visual acuity,oblique muscle function,and stereopsis records were collected.RESULTS:Among the 843 eligible patients,91(10.79%;39 males and 52 females)had A-pattern(54,6.4%)or V-pattern(37,4.4%).Age at onset of vision impairment was 4±5y and at the time of surgery was 25±9y.Statistically significant negative correlations were present between impaired visual acuity and the pre-operative exodeviation(r=-0.198,P=0.016)and patterns(r=-0.207,P=0.015).Age at surgery and exodeviation in patients with concomitant A-V pattern exotropia was significantly earlier as compared with that of sensory A-V pattern exotropia and sensory exotropia(both P<0.0001).There were no significant differences in these clinical variables between sensory exotropia with or without A-V pattern.Deviation and pattern were significantly reduced in patients receiving horizontal rectus surgery with or without oblique muscle surgery(both P<0.0001).CONCLUSION:The prevalence of sensory A-V pattern exotropia in our study is 10.79%.Visual acuity represents an important factor contributing to the occurrence and development of A-V pattern.Isolated horizontal rectus surgery can provide a good option for the correction of sensory A-V pattern exotropia.
基金supported by the National Natural Science Foundation of China(Grant Nos.42330610 and 42075010)。
文摘The Sichuan Basin(SCB),China has a high incidence of extremely persistent heavy rainfall(EPHR)events.The EPHR events from 2009 to 2019 in the SCB were mainly concentrated over the northern and northwestern windward slopes and the central basin.They occurred from June to September,but especially in July,and peaked at 0300 LST.ERA5 reanalysis data and objective classification were used to investigate the synoptic patterns and their effects.There were three synoptic patterns during EPHR events,all accompanied by a Southwest Vortex.The location and intensity of the Southwest Vortex,thermal forcing of the Tibetan Plateau(TP),and low-level winds can greatly affect the intensity and spatial distribution of EPHR.When the Southwest Vortex was located in the western SCB and there were southerly low-level jets(LLJs),convergence and upslope wind would lead to EPHR over the northwestern or northern windward slopes.If there was no LLJ and the whole SCB was under the center of the Southwest Vortex,nocturnal EPHR was controlled by the internal circulation of the Southwest Vortex and the updraft generated by the thermal forcing of the TP,and the rainfall was weaker.The southeastern entrance of the SCB was a key area where the low-level wind dominated the nocturnal peak of EPHR.The nocturnal strengthened southeasterly wind in the key area is attributable to inertial oscillation,and the topographic friction plays an essential role in transporting momentum and moisture into the basin by generating easterly and northeasterly ageostrophic winds.
文摘BACKGROUND The microcystic,elongated,and fragmented(MELF)pattern of invasion in endometrioid endometrial carcinoma(EEC)is a special mode of myometrial invasion that has been recently recognized by the pathology community.Overex-pression of CXC chemokine receptor 4(CXCR4)in tumor cells contributes to tumor growth,invasion,angiogenesis,metastasis,and recurrence.AIM To explore the correlation between CXCR4 expression in EEC and MELF invasion and clinicopathological features.METHODS A total of 205 EEC patients treated at Peking University People’s Hospital from June 2020 to December 2021 were selected(60 cases with MELF invasion,145 cases without).The clinicopathological features of the two groups were compared,and expression of CXCR4 protein,estrogen receptor,and progesterone receptor was detected and compared by immunohistochemistry.RESULTS EEC with MELF invasion was significantly associated with low tumor grade,lymphovascular space invasion,deep myometrial invasion,cervical stromal involvement,and lymph node metastasis.There was a difference in CXCR4 expression between the two groups,with the MELF group having a significantly higher expression than the non-MELF group.CONCLUSION CXCR4 expression is significantly increased in EEC with MELF invasion and in the MELF invasion area,which may promote tumor invasion and metastasis and has some value for prognostic assessment.
基金supported by the Strategic Technology Project of Chinese Academy of Sciences (XDA05060300)the Science and Technology R&D Program of Shaanxi Province (2011KJXX63)
文摘Fractal theory is becoming an increasingly useful tool to describe soil structure dynamics for a better understanding of the performance of soil systems. Changes in land use patterns significantly affect soil physical, chemical and biological properties. However, limited information is available on the fractal characteristics of deep soil layers under different land use patterns. In this study, the fractal dimensions of particle size distribution（PSD） and micro-aggregates in the 0–500 cm soil profile and soil anti-erodibility in the 0–10 cm soil profile for 10 typical land use patterns were investigated in the Zhifanggou Watershed on the Loess Plateau, China. The 10 typical land use patterns were： slope cropland, two terraced croplands, check-dam cropland, woodland, two shrublands, orchard, artificial and natural grasslands. The results showed that the fractal dimensions of PSD and micro-aggregates were all significantly influenced by soil depths, land use patterns and their interaction. The plantations of shrubland, woodland and natural grassland increased the amount of larger micro-aggregates, and decreased the fractal dimensions of micro-aggregates in the 0–40 cm soil profile. And they also improved the aggregate state and aggregate degree and decreased dispersion rate in the 0–10 cm soil profile. The results indicated that fractal theory can be used to characterize soil structure under different land use patterns and fractal dimensions of micro-aggregates were more effective in this regard. The natural grassland may be the best choice for improving soil structure in the study area.
基金the Human Resources Development Program for the Outstanding Talents in The Fifth People’s Hospital of Shanghai,Fudan University,No.2017WYRCJY09the Key Medical Speciality of The Fifth People’s Hospital of Shanghai,Fudan University,No.2017WY202K08
文摘BACKGROUND Different histological growth patterns(HGPs)of colorectal carcinoma(CRC)liver metastasis are associated with patients’prognosis and response to antiangiogenic therapy.However,the relationship between HGPs of liver metastasis and clinicopathological and genomic characteristics of primary cancer has not been well established.AIM To assess whether certain clinicopathological and genomic features of primary CRC could predict the HGPs of liver metastasis.METHODS A total of 29 patients with paired resections of both primary CRC and liver metastasis were divided into two groups:A(15 cases with desmoplastic liver metastasis)and B(14 cases with replacement liver metastasis).Clinical information was obtained from patients’charts.Mismatch repair proteins,BRAFV600E,and PD-L1 were evaluated by immunohistochemistry.Five cases were selected randomly from each group for whole exome sequencing(WES)analysis.RESULTS In the primary tumor,expanding growth pattern,low tumor budding score(TBS),and Crohn’s disease-like response(CDR)were associated with desmoplastic liver metastasis and better overall survival,whereas infiltrating growth pattern alone of primary carcinoma could predict the replacement liver metastasis and worse overall survival(P<0.05).On WES analysis,primary carcinoma with desmoplastic liver metastasis showed mutations in APC(4/5);TP53(3/5);KRAS,PIK3CA,and FAT4(2/5);BRCA-1,BRCA2,BRAF,and DNAH5(1/5),whereas primary carcinoma with replacement liver metastasis showed mutations in APC and TP53(3/5);KRAS,FAT4,DNH5,SMAD,ERBB2,ERBB3,LRP1,and SDK1(1/5).CONCLUSION The HGPs,TBS,and CDR of primary CRC as well as the presence of specific genetic mutations such as those in PIK3CA could be used to predict the HGPs of liver metastasis,response to therapy,and patients’prognosis.
文摘Recent exploration results indicate that a significant exploration potential remains in the Dongying Depression of the Bohai Bay Basin and the undiscovered oil and gas are largely reservoired in subtle traps including turbidite litholigcal traps of the Sha-3 Member. In order to effectively guide the exploration program targeting turbidites, this study will focus on the depositional models of the Sha-3 Member turbidites and oil/gas accumulation characteristics in these turbidites. Two corresponding relationships were found. One is that the East African Rift Valley provides a modern analog for the depositional systems in the Dongying Depression. The other is that the depositional models of line-sourced slope aprons, single point-source submarine fan and multiple source ramp turbidite, established for deep-sea turbidites, can be applied to interpret the depositional features of the turbidite fans of three different origins: slope turbidite aprons, lake floor turbidite fans and delta-fed turbidite fans in the Sha-3 Member. Updip sealing integrity is the key factor determining whether oil/gas accumulates or not in the slope aprons and lake floor fans. The factors controlling oil/gas migration and accumulation in the delta-fed turbidite fans are not very clear. Multiple factors rather than a single factor probably played significant roles in these processes.
文摘In this paper, three types of weld flaw were taken as target, evaluation and recognition of flaw echo features were studied. On the basis of experimental study and theoretical analysis, 26 features have been extracted from each echo samples. A method which is based on the xtatislical hypothesis testing and used for feature evaluation and optimum subset selection was explored. Thus, the dimensionality reduction of feature space was brought out, and simultaneously the amount of calculation was decreased. An intelligent pattern classifier with B-P type neural network was constructed which was characterized by high speed and accuracy for learning. Using a half of total samples as training set and others as testing set, the learning efficiency and the classification ability of network model were studied. The results of experiment showed that the learning rate of different training samples was about 100%. The results of recognition was satisfactory when the optimum feature subset was taken as the sample's feature vectors. The average recognition rate of three type flaws was about 87.6%, and the best recognition rate amounted to 97%.
文摘In this study, we determine differences in total biomass of soil microorganisms and community structure (using the most probable number of bacteria (MPN) and the number of fungal genera) in patterned ground features (PGF) and adjacent vegetated soils (AVS) in mesic sites from three High Arctic islands in order to characterize microbial dynamics as affected by cryoturbation, and a broad bioclimatic gradient. We also characterize total biomass of soil microorganisms and the most probable number of bacteria along a topographic gradient within each bioclimatic subzone to evaluate whether differences in topography lead to differences in microbial dynamics at a smaller scale. We found total microbial biomass C, the most probable number of heterotrophic bacteria, and fungal genera vary along this bioclimatic gradient. Microbial biomass C decreased with increasing latitude. Overall, microbial biomass C, MPN and the number of fungal isolates were higher in AVS than in PGFs. The effects which topographic position had on microbial biomass C varied across the bioclimatic gradient as there was no effect of topographic position in Isachsen (subzone A) and Mould Bay (subzone B), when compared to Green Cabin (subzone C, warmer site).There was no effect of topographic position on MPN counts at Mould Bay and Green Cabin. However, in Isachsen, MPN counts were highest in the wet topographic position as compared to the mesic and dry. In conclusion, PGFs seem to decouple the effect climate that might have on the total biomass of soil microorganisms along the bioclimatic gradient;and influence gets ameliorated as latitude increases. Similarly, the effect of topography on the total microbial biomass is significant at the warmest bioclimatic zone of the gradient. Thus, climate and topographic effects on total microbial biomass increase with warmer climate.
文摘In this paper we used two new features i.e. T-wave integral and total integral as extracted feature from one cycle of normal and patient ECG signals to detection and localization of myocardial infarction (MI) in left ventricle of heart. In our previous work we used some features of body surface potential map data for this aim. But we know the standard ECG is more popular, so we focused our detection and localization of MI on standard ECG. We use the T-wave integral because this feature is important impression of T-wave in MI. The second feature in this research is total integral of one ECG cycle, because we believe that the MI affects the morphology of the ECG signal which leads to total integral changes. We used some pattern recognition method such as Artificial Neural Network (ANN) to detect and localize the MI, because this method has very good accuracy for classification of normal signal and abnormal signal. We used one type of Radial Basis Function (RBF) that called Probabilistic Neural Network (PNN) because of its nonlinearity property, and used other classifier such as k-Nearest Neighbors (KNN), Multilayer Perceptron (MLP) and Naive Bayes Classification. We used PhysioNet database as our training and test data. We reached over 76% for accuracy in test data for localization and over 94% for detection of MI. Main advantages of our method are simplicity and its good accuracy. Also we can improve the accuracy of classification by adding more features in this method. A simple method based on using only two features which were extracted from standard ECG is presented and has good accuracy in MI localization.
文摘Five-electrode configurations were designed to simulate the distribution inhomogeneity of electric field intensities in the air-insulating medium, and the characteristic data waveforms of partial discharge generated by different electrode configurations under the excitation of power frequency AC voltage were carefully collected in this paper. Furthermore, the feature vectors of the corresponding fingerprint, contained in partial discharge data, were extracted by rigorous mathematical algorithms, and the artificial neural network was employed to realize the pattern recognition of partial discharge caused by the inhomogeneity of electric field intensity with different electrode configurations. The results indicate that the J<sub>4</sub> value in the space of 7 feature quantities is 1905.6, and the recognition rate is 100% when the hidden layer neuron of the network is 19. However, the J<sub>5</sub> value of 9 feature quantities is 1589.9, and the purpose of recognition has been achieved when the number of hidden layer neurons of the network is 6. Increasing the number of hidden layer neurons will only waste computing resources. Of course, PD information collection mode, feature quantity selection, optimal feature space composition, network structure and classification algorithm are the key to realizing PD fault intelligence identification.
文摘In the article“A Lightweight Approach for Skin Lesion Detection through Optimal Features Fusion”by Khadija Manzoor,Fiaz Majeed,Ansar Siddique,Talha Meraj,Hafiz Tayyab Rauf,Mohammed A.El-Meligy,Mohamed Sharaf,Abd Elatty E.Abd Elgawad Computers,Materials&Continua,2022,Vol.70,No.1,pp.1617–1630.DOI:10.32604/cmc.2022.018621,URL:https://www.techscience.com/cmc/v70n1/44361,there was an error regarding the affiliation for the author Hafiz Tayyab Rauf.Instead of“Centre for Smart Systems,AI and Cybersecurity,Staffordshire University,Stoke-on-Trent,UK”,the affiliation should be“Independent Researcher,Bradford,BD80HS,UK”.
基金Supported by the National Natural Science Foundation of China (No.40606036)the National High Technology Research and Development Program (863 Program) (No.200lAA6360l0)the National Basic Research Program of China (973 Program) (No.2006CB400606)
文摘Two field studies were conducted to measure pigments in the Southern Yellow Sea (SYS) and the northern East China Sea (NECS) in April (spring) and September (autumn) to evaluate the distribution pattern of phytoplankton stock (Chl a concentration) and the impact of hydrological features such as water mass,mixing and tidal front on these patterns.The results indicated that the Chl a concentration was 2.43±2.64 (Mean ± SD) mg m-3 in April (range,0.35 to 17.02 mg m-3) and 1.75±3.10 mg m-3 in September (from 0.07 to 36.54 mg m-3) in 2003.Additionally,four areas with higher Chl a concentrations were observed in the surface water in April,while two were observed in September,and these areas were located within or near the point at which different water masses converged (temperature front area).The distribution pattern of Chl a was generally consistent between onshore and offshore stations at different depths in April and September.Specifically,higher Chl a concentrations were observed along the coastal line in September,which consisted of a mixing area and a tidal front area,although the distributional pattern of Chl a concentrations varied along transects in April.The maximum Chl a concentration at each station was observed in the surface and subsurface layer (0-10 m) for onshore stations and the thermocline layer (10-30 m) for offshore stations in September,while the greatest concentrations were generally observed in surface and subsurface water (0-10 m) in April.The formation of the Chl a distributional pattern in the SYS and NECS and its relationship with possible influencing factors is also discussed.Although physical forces had a close relationship with Chl a distribution,more data are required to clearly and comprehensively elucidate the spatial pattern dynamics of Chl a in the SYS and NECS.
基金This work was supported by the National Natural Science Foundation of China(31730031)the National Key Research and Development Program of China(2017YFA0104700 and 2016YFC1101603)the Jiangsu Provincial Key Medical Center and Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
文摘The molecular network features of spinal cord development that are integral to tissue engineering remain poorly understood in placental mammals,especially in terms of their relationships with vital biological processes such as regeneration.Here,using a large-scale temporal transcriptomic analysis of rat spinal cord from the embryonic stage to adulthood,we show that fluctuating RNA expression levels reflect highly active transcriptional regulation,which may initiate spinal cord patterning.We also demonstrate that microRNAs(miRNAs)and transcriptional factors exhibit a mosaic profile based on their expression patterns,while differential alternative splicing events reveal that alternative splicing may be a driving force for the development of the node of Ranvier.Our study also supports the existence of a negative correlation between innate immunity and intrinsic growth capacity.Epigenetic modifications appear to perform their respective regulatory functions at different stages of development,while guanine nucleotidebinding protein(G protein)-coupled receptors(including olfactory receptors(ORs))may perform pleiotropic roles in axonal growth.This study provides a valuable resource for investigating spinal cord development and complements the increasing number of single-cell datasets.These findings also provide a genetic basis for the development of novel tissue engineering strategies.
基金The investigation has been carried out within the SB RAS Program Ⅲ.20.2 for Basic Researchat partial financial support of the RFBR Grant No.11-08-12069-ofi-m-2011+1 种基金the Project No.5 of the Belarus NASSB RAS Program for Joint Basic Research
文摘The results of a theoretical study on the influence of strength of interphase boundaries in metal-ceramic composite on macroscopical characteristics of composite response such as strength, deformation capacity, fracture energy and fracture pattern are presented. The study was conducted by means of computer-aided simulation by means of movable cellular automaton method taking account of a developed ＂mesoscopical＂ structural model of particle-reinforced composite. The strength of interphase boundaries is found to be a key structural factor determining not only the strength properties of metal-ceramic composite, but also the pattern and rate of fracture. The principles for achievement of the high-strength values of particle/binder interfaces in the metal-ceramic composition due to the formation of the wide transition zones （areas of variable chemical composition） at the interphase boundaries are discussed. Simulation results confirm that such transition zones provide a change in fracture mechanism and make the achievement of a high-strength and a high deformation capacity of metal-ceramic composite possible.
文摘BACKGROUND Pancreatic cancer remains one of the most lethal malignancies worldwide,with a poor prognosis often attributed to late diagnosis.Understanding the correlation between pathological type and imaging features is crucial for early detection and appropriate treatment planning.AIM To retrospectively analyze the relationship between different pathological types of pancreatic cancer and their corresponding imaging features.METHODS We retrospectively analyzed the data of 500 patients diagnosed with pancreatic cancer between January 2010 and December 2020 at our institution.Pathological types were determined by histopathological examination of the surgical spe-cimens or biopsy samples.The imaging features were assessed using computed tomography,magnetic resonance imaging,and endoscopic ultrasound.Statistical analyses were performed to identify significant associations between pathological types and specific imaging characteristics.RESULTS There were 320(64%)cases of pancreatic ductal adenocarcinoma,75(15%)of intraductal papillary mucinous neoplasms,50(10%)of neuroendocrine tumors,and 55(11%)of other rare types.Distinct imaging features were identified in each pathological type.Pancreatic ductal adenocarcinoma typically presents as a hypodense mass with poorly defined borders on computed tomography,whereas intraductal papillary mucinous neoplasms present as characteristic cystic lesions with mural nodules.Neuroendocrine tumors often appear as hypervascular lesions in contrast-enhanced imaging.Statistical analysis revealed significant correlations between specific imaging features and pathological types(P<0.001).CONCLUSION This study demonstrated a strong association between the pathological types of pancreatic cancer and imaging features.These findings can enhance the accuracy of noninvasive diagnosis and guide personalized treatment approaches.
文摘During Donald Trump’s first term,the“Trump Shock”brought world politics into an era of uncertainties and pulled the transatlantic alliance down to its lowest point in history.The Trump 2.0 tsunami brewed by the 2024 presidential election of the United States has plunged the U.S.-Europe relations into more gloomy waters,ushering in a more complex and turbulent period of adjustment.
