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Developmental toxicity assessment of neonicotinoids and organophosphate esters with a human embryonic stem cell-and metabolism-based fast-screening model 被引量:2
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作者 Shuxian Zhang Miaomiao Zhao +3 位作者 Shichang Li Renjun Yang Nuoya Yin Francesco Faiola 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2024年第3期370-381,共12页
In recent years,neonicotinoids(NEOs)and organophosphate esters(OPEs)have been widely used as substitutes for traditional pesticides and brominated fame-retardants,respectively.Previous studies have shown that those co... In recent years,neonicotinoids(NEOs)and organophosphate esters(OPEs)have been widely used as substitutes for traditional pesticides and brominated fame-retardants,respectively.Previous studies have shown that those compounds can be frequently detected in environmental and human samples,are able to penetrate the placental barrier,and are toxic to animals.Thus,it is reasonable to speculate that NEOs and OPEs may have potential adverse effects in humans,especially during development.We employed a human embryonic stem cell differentiation-and liver S9 fraction metabolism-based fast screening model to assess the potential embryonic toxicity of those two types of chemicals.We show that four NEO and five OPE prototypes targeted mostly ectoderm specification,as neural ectoderm and neural crest genes were down-regulated,and surface ectoderm and placode markers up-regulated.Human liver S9 fraction's treatment could generally reduce the effects of the chemicals,except in a few specific instances,indicating the liver may detoxify NEOs and OPEs.Our findings suggest that NEOs and OPEs interfere with human early embryonic development. 展开更多
关键词 NEONICOTINOIDS Organophosphate esters Human embryonic stem cells fast screening model Developmental toxicity
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Fast forward modeling of muon transmission tomography based on model voxelization ray energy loss projection
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作者 Zhang Rong-Qing Xi Zhen-Zhu +2 位作者 Liu Wei Wang He Yang Zi-Yan 《Applied Geophysics》 SCIE CSCD 2022年第3期395-408,471,共15页
To solve the problems associated with low resolution and high computational effort infinite time,this paper proposes a fast forward modeling method for muon energy loss transmission tomography based on a model voxeliza... To solve the problems associated with low resolution and high computational effort infinite time,this paper proposes a fast forward modeling method for muon energy loss transmission tomography based on a model voxelization energy loss projection algorithm.First,the energy loss equation for muon transmission tomography is derived from the Bethe–Bloch formula,and the imaging region is then dissected into several units using the model voxelization method.Thereafter,the three-dimensional(3-D)imaging model is discretized into parallel and equally spaced two-dimensional(2-D)slices using the model layering method to realize a dimensional reduction of the 3-D volume data and accelerate the forward calculation speed.Subsequently,the muon energy loss transmission tomography equation is discretized using the ray energy loss projection method to establish a set of energy loss equations for the muon penetration voxel model.Finally,the muon energy loss values at the outgoing point are obtained by solving the projection coefficient matrix of the ray length-weighted model,achieving a significant reduction in the number of muons and improving the computational efficiency.A comparison of our results with the simulation results based on the Monte Carlo method verifies the accuracy and effectiveness of the algorithm proposed in this paper.The metallic mineral identification tests show that the proposed algorithm can quickly identify high-density metallic minerals.The muon energy loss response can accurately identify the boundary of the anomalies and their spatial distribution characteristics. 展开更多
关键词 Muon transmission tomography model voxelization ray energy loss projection fast forward modeling Monte Carlo simulation
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A Fast Version of LASG/IAP Climate System Model and Its 1000-year Control Integration 被引量:39
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作者 周天军 吴波 +2 位作者 闻新宇 李立娟 王斌 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2008年第4期655-672,共18页
A fast version of the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics (LASG)/Institute of Atmospheric Physics (IAP) climate system model is briefly documented. Th... A fast version of the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics (LASG)/Institute of Atmospheric Physics (IAP) climate system model is briefly documented. The fast coupled model employs a low resolution version of the atmospheric component Grid Atmospheric Model of IAP/LASG (GAMIL), with the other parts of the model, namely an oceanic component LASG/IAP Climate Ocean Model (LICOM), land component Common Land Model (CLM), and sea ice component from National Center for Atmospheric Research Community Climate System Model (NCAR CCSM2), as the same as in the standard version of LASG/IAP Flexible Global Ocean Atmosphere Land System model (FGOALS_g). The parameterizations of physical and dynamical processes of the atmospheric component in the fast version are identical to the standard version, although some parameter values are different. However, by virtue of reduced horizontal resolution and increased time-step of the most time-consuming atmospheric component, it runs faster by a factor of 3 and can serve as a useful tool for longterm and large-ensemble integrations. A 1000-year control simulation of the present-day climate has been completed without flux adjustments. The final 600 years of this simulation has virtually no trends in global mean sea surface temperatures and is recommended for internal variability studies. Several aspects of the control simulation's mean climate and variability are evaluated against the observational or reanalysis data. The strengths and weaknesses of the control simulation are evaluated. The mean atmospheric circulation is well simulated, except in high latitudes. The Asian-Australian monsoonal meridional cell shows realistic features, however, an artificial rainfall center is located to the eastern periphery of the Tibetan Plateau persists throughout the year. The mean bias of SST resembles that of the standard version, appearing as a "double ITCZ" (Inter-Tropical Convergence Zone) associated with a westward extension of the equatorial eastern Pacific cold tongue. The sea ice extent is acceptable but has a higher concentration. The strength of Atlantic meridional overturning is 27.5 Sv. Evidence from the 600-year simulation suggests a modulation of internal variability on ENSO frequency, since both regular and irregular oscillations of ENSO are found during the different time periods of the long-term simulation. 展开更多
关键词 fast ocean-atmosphere coupled model low resolution model evaluation
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Cooperative interception with fast multiple model adaptive estimation 被引量:3
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作者 Shao-bo Wang Yang Guo +2 位作者 Shi-cheng Wang Zhi-guo Liu Shuai Zhang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2021年第6期1905-1917,共13页
For the case that two pursuers intercept an evasive target,the cooperative strategies and state estimation methods taken by pursuers can seriously affect the guidance accuracy for the target,which performs a bang For ... For the case that two pursuers intercept an evasive target,the cooperative strategies and state estimation methods taken by pursuers can seriously affect the guidance accuracy for the target,which performs a bang For the case that two pursuers intercept an evasive target,the cooperative strategies and state estimation methods taken by pursuers can seriously affect the guidance accuracy for the target,which performs a bang-bang evasive maneuver with a random switching time.Combined Fast multiple model adaptive estimation(Fast MMAE)algorithm,the cooperative guidance law takes detection configuration affecting the accuracy of interception into consideration.Introduced the detection error model related to the line-of-sight(LOS)separation angle of two interceptors,an optimal cooperative guidance law solving the optimization problem is designed to modulate the LOS separation angle to reduce the estimation error and improve the interception performance.Due to the uncertainty of the target bang-bang maneuver switching time and the effective fitting of its multi-modal motion,Fast MMAE is introduced to identify its maneuver switching time and estimate the acceleration of the target to track and intercept the target accurately.The designed cooperative optimal guidance law with Fast MMAE has better estimation ability and interception performance than the traditional guidance law and estimation method via Monte Carlo simulation. 展开更多
关键词 Cooperative guidance Optimal control fast multiple model adaptive estimation (fast MMAE) Bang-bang maneuver Switch time Detection configuration Estimation error
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Dynamic Visual Image Modeling Based on Mobile RobotSelf- Organizing Network in Internetof Things Perception Layer 被引量:1
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作者 高立 任旭鹏 李晓博 《China Communications》 SCIE CSCD 2011年第8期49-55,共7页
The dynamic multichannel binocular visual image modeling is studied based on Internet of Things (IoT) Perception Layer, using mobile robot self-organizing network. By employing multigroup mobile robots with binocular ... The dynamic multichannel binocular visual image modeling is studied based on Internet of Things (IoT) Perception Layer, using mobile robot self-organizing network. By employing multigroup mobile robots with binocular visual system, the real visual images of the object will be obtained. Then through the mobile self-organizing network, a three-dimensional model is rebuilt by synthesizing the returned images. On this basis, we formalize a novel algorithm for multichannel binocular visual three-dimensional images based on fast three-dimensional modeling. Compared with the method based on single binocular visual system, the new algorithm can improve the Integrity and accuracy of the dynamic three-dimensional object modeling. The simulation results show that the new method can effectively accelerate the modeling speed, improve the similarity and not increase the data size. 展开更多
关键词 IoT perception layer multigroup binocular visual dynamic visual image modeling fast three-dimensional modeling rebuild
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Model-based design method of two-axis four-actuator fast steering mirror system 被引量:3
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作者 黑沫 张连超 +2 位作者 周擎坤 鲁亚飞 范大鹏 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第1期150-158,共9页
This work was focused on the model-based design method of two-axis four-actuator(TAFA) fast steering mirror system(FSM), in order to improve the design efficiency. The structure and operation principle commonality of ... This work was focused on the model-based design method of two-axis four-actuator(TAFA) fast steering mirror system(FSM), in order to improve the design efficiency. The structure and operation principle commonality of normal TAFA FSM were investigated. Based on the structure and the commonality, the conditions of single-axis idea, high-frequency resonance and coupling were modeled gradually. Combining these models, a holonomic system model was established to reflect and predict the performance of TAFA FSM. A model-based design method was proposed based on the holonomic system model. The design flow and design concept of the method were described. In accordance with the method, a TAFA FSM was designed. Simulations and experiments of the FSM were done, and the results of them were compared. The compared results indicate that the holonomic system model can well reflect and predict the performance of TAFA FSM. The bandwidth of TAFA FSM is more than 250 Hz; adjust time is less than 15 ms;overshoot is less than 8%; position accuracy is better than 10 μrad; the FSM prototype can satisfy the requirements. 展开更多
关键词 fast steering mirror system model-based design dynamic modeling
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Remote forcing of Indian Ocean warming on Northwest Pacific during El Nio decaying years:a FOAM model approach
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作者 胡海波 洪晓媛 +4 位作者 张媛 杨修群 刘伟 卢华国 杨建玲 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2013年第6期1363-1371,共9页
This paper attempts to analyze in detail the remote influence of the Indian Ocean Basin warming on the Northwest Pacific (NWP) during the year of decaying E1 Nifio. Observation data and the Fast Ocean- Atmosphere co... This paper attempts to analyze in detail the remote influence of the Indian Ocean Basin warming on the Northwest Pacific (NWP) during the year of decaying E1 Nifio. Observation data and the Fast Ocean- Atmosphere coupled Model 1.5 were used to investigate the triggering conditions under which the remote influence is formed between the positive sea surface temperature (SST) anomaly in the North Indian Ocean and the Anomalous Northwest Pacific anticyclone (ANWPA). Our research show that it is only when there is a contributory background wind field over the Indian Ocean, i,e., when the Indian Summer Monsoon (ISM) reaches its peak, that the warmer SST anomaly in the North Indian Ocean incites significant easterly wind anomalies in the lower atmosphere of the Indo-West tropical Pacific. This then produces the remote influence on the ANWPA. Therefore, the SST anomaly in the North Indian Ocean might interfere with the prediction of the East Asia Summer Monsoon in the year of decaying E1 Nifio. Both the sustaining effect of local negative SST anomalies in the NWP, and the remote effect of positive SST anomalies in the North Indian Ocean on the ANWPA, should be considered in further research. 展开更多
关键词 E1Nno decaying year Indian Ocean Basin warming (lOB warming) Indian Summer Monsoon (ISM) fast Ocean-Amaosphere Model 1.5 (FOAM1.5) anomalous Northwest Pacific (NWP) anticyclone
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Rapid prediction of floating and sinking components of raw coal
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作者 Wang Guanghui Kuang Yali Wang Zhangguo Ji Li Wang Ying 《International Journal of Mining Science and Technology》 SCIE EI 2012年第5期735-738,共4页
A model that rapidly predicts the density components of raw coal is described.It is based on a threegrade fast float/sink test.The recent comprehensive monthly floating and sinking data are used for comparison.The pre... A model that rapidly predicts the density components of raw coal is described.It is based on a threegrade fast float/sink test.The recent comprehensive monthly floating and sinking data are used for comparison.The predicted data are used to draw washability curves and to provide a rapid evaluation of the effect from heavy medium induced separation.Thirty-one production shifts worth of fast float/sink data and the corresponding quick ash data are used to verify the model.The results show a small error with an arithmetic average of 0.53 and an absolute average error of 1.50.This indicates that this model has high precision.The theoretical yield from the washability curves is 76.47% for the monthly comprehensive data and 81.31% using the model data.This is for a desired cleaned coal ash of 9%.The relative error between these two is 6.33%,which is small and indicates that the predicted data can be used to rapidly evaluate the separation effect of gravity separation equipment. 展开更多
关键词 Raw coal Floating and sinking components fast floating and sinking data Predicting model
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Satellite-Derived Bathymetry Using a Fast Feature Cascade Learning Model in Turbid Coastal Waters
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作者 Zhongqiang Wu Yuchen Zhao +4 位作者 Shulei Wu Huong Chen Chunhui Song Zhihua Mao Wei Shen 《Journal of Remote Sensing》 2024年第1期163-177,共15页
Obtaining accurate bathymetric maps is very valuable for marine environment monitoring,port planning,and so on.Accurately estimating water depth in turbid coastal waters using satellite remote sensing encounters chall... Obtaining accurate bathymetric maps is very valuable for marine environment monitoring,port planning,and so on.Accurately estimating water depth in turbid coastal waters using satellite remote sensing encounters challenges originating from low water transparency,but it is limited by the quantity,quality,and water quality of samples.This study introduces a fast feature cascade learning model(FFCLM)to enhance the accuracy of bathymetric inversion from multispectral satellite images,particularly when limited field samples are available.FFCLM leverages spectral bands and in situ data to derive effective inversion weights through feature concatenation and cascade fitting.Field experiments conducted at Nanshan Port and Rushikonda Beach gathered water depth,satellite,and in situ data.Comparative analysis with conventional machine learning algorithms,including support vector machine,random forest,and gradient boosting trees,indicates that FFCLM achieves lower errors and demonstrates more robust performance across study areas.This is especially more pronounced when using small training samples(n<100).Examination of key parameters and water depth profiles highlights FFCLM’s advantages in generalization and deep-water inversion.This study presents an efficient solution for small-sample bathymetric mapping in turbid coastal waters,utilizing spectral and physical information to overcome sample size limitations and enhancing satellite remote sensing capabilities for shallow water monitoring. 展开更多
关键词 obtaining accurate bathymetric maps satellite imagesparticularly bathymetric inversion satellite derived bathymetry estimating water depth marine environment monitoringport planningand fast feature cascade learning model ffclm fast feature cascade learning model
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Minimizing transformer inference overhead using controlling element on Shenwei AI accelerator
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作者 Yulong ZHAO Chunzhi WU +7 位作者 Yizhuo WANG Lufei ZHANG Yaguang ZHANG Wenyuan SHEN Hao FAN Hankang FANG Yi QIN Xin LIU 《Frontiers of Information Technology & Electronic Engineering》 2025年第4期605-622,共18页
Transformer models have become a cornerstone of various natural language processing(NLP)tasks.However,the substantial computational overhead during the inference remains a significant challenge,limiting their deployme... Transformer models have become a cornerstone of various natural language processing(NLP)tasks.However,the substantial computational overhead during the inference remains a significant challenge,limiting their deployment in practical applications.In this study,we address this challenge by minimizing the inference overhead in transformer models using the controlling element on artificial intelligence(AI)accelerators.Our work is anchored by four key contributions.First,we conduct a comprehensive analysis of the overhead composition within the transformer inference process,identifying the primary bottlenecks.Second,we leverage the management processing element(MPE)of the Shenwei AI(SWAI)accelerator,implementing a three-tier scheduling framework that significantly reduces the number of host-device launches to approximately 1/10000 of the original PyTorch-GPU setup.Third,we introduce a zero-copy memory management technique using segment-page fusion,which significantly reduces memory access latency and improves overall inference efficiency.Finally,we develop a fast model loading method that eliminates redundant computations during model verification and initialization,reducing the total loading time for large models from 22128.31 ms to 1041.72 ms.Our contributions significantly enhance the optimization of transformer models,enabling more efficient and expedited inference processes on AI accelerators. 展开更多
关键词 Transformer inference optimization Three-tier scheduling Zero-copy memory management fast model loading
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Modeling for assembly simulations:Data description and a data-driven construction framework
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作者 Lihong Qiao Yifan Qie Yixin Zhu 《International Journal of Modeling, Simulation, and Scientific Computing》 EI 2017年第2期220-231,共12页
Assembly simulations such as assembly process simulation and assembly tolerance simulation have become an effective means to evaluate and analyze product assembly design and assembly process planning.Being core aspec... Assembly simulations such as assembly process simulation and assembly tolerance simulation have become an effective means to evaluate and analyze product assembly design and assembly process planning.Being core aspect of simulation implementation,building an assembly simulation model is rather time-consuming because of its high complexity.Furthermore,modeling has a significant influence on the popularization and application of simulation technology.In this paper,data needed by assembly process and tolerance simulation are addressed to propose a data-driven approach for assembly simulation modeling.The application process and the architecture of modeling framework for assembly simulation are presented as well.An assembly sequence simulation example is given to illustrate the application of the framework.The framework provides a new idea for the realization of automatic modeling for assembly simulation. 展开更多
关键词 Assembly simulation fast modeling data-driven.
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A head-related transfer function model for fast synthesizing multiple virtual sound sources 被引量:1
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作者 LIANG Zhiqiang XIE Bosun 《Chinese Journal of Acoustics》 2013年第2期175-188,共14页
A head-related transfer function (HRTF) model for fast and real-time synthesizing multiple virtual sound sources is proposed. A head-related impulse response (HRIR, time- domain version of HRTF) is first decompose... A head-related transfer function (HRTF) model for fast and real-time synthesizing multiple virtual sound sources is proposed. A head-related impulse response (HRIR, time- domain version of HRTF) is first decomposed by a two-level wavelet packet and then represented by a model composed of subband filters and reconstruction filters. The coefficients of the subband filters are the zero interpolation of the wavelet coefficients of the HRIR. The coefficients of the reconstruction filters can be calculated from the wavelet function. The model is simplified by applying a threshold method to reduce the wavelet coefficients. The calculated results indicate that for a model with 30 wavelet coefficients, the error of reconstructed HRIR is about 1%. And the result of a psychoacoustic test shows that a model with 35 wavelet coefficients is perceptually indistinguishable from the original HRIR. When multiple virtual sound sources are synthesized simultaneously, the computational cost of the proposed model is much less than the traditional HRTF filters. 展开更多
关键词 HRIR HRTF A head-related transfer function model for fast synthesizing multiple virtual sound sources HEAD
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