心血管疾病(cardiovascular disease, CVD)是全球发病率和死亡率的主要原因,严重威胁着全球人类的健康。CVD包含疾病有多种其中急性心肌梗死(AMI)是最常见严重危害中老年人群健康的心血管疾病之一,血清甘油三酯葡萄糖指数(triglyceride-...心血管疾病(cardiovascular disease, CVD)是全球发病率和死亡率的主要原因,严重威胁着全球人类的健康。CVD包含疾病有多种其中急性心肌梗死(AMI)是最常见严重危害中老年人群健康的心血管疾病之一,血清甘油三酯葡萄糖指数(triglyceride-glucose index, TyG指数)是胰岛素抵抗(insulin resistance, IR)的一种新型替代指标,为条件受限地区临床决策提供有力依据。有研究指出TyG指数不仅可预测CVD、2型糖尿病的发生发展,还可评估代谢性疾病发生。SII对冠心病患者介入治疗后发生不良心血管事件的预测价值优于传统危险。FAR在预测主要心血管不良事件尤其是合并DM方面比单独用FIB和Alb有更高敏感性和特异性。本文旨在阐述TyG指数与FIB/Alb比值(FAR)、SII在AMI患者中冠脉病变严重程度的发生发展关系,以便更好地了解TyG指数、FIB/Alb比值(FAR)、SII在AMI中的应用价值。Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide and poses a serious threat to human health worldwide. CVD includes a variety of diseases, among which acute myocardial infarction (AMI) is one of the most common cardiovascular diseases that seriously harm the health of middle-aged and elderly people. Serum triglyceride-glucose index (TyG index) is a novel proxy for insulin resistance (IR), which provides a strong basis for clinical decision-making in restricted areas. Some studies have pointed out that TyG index can not only predict the occurrence and development of CVD and type 2 diabetes, but also evaluate the occurrence of metabolic diseases. The predictive value of SII for adverse cardiovascular events in patients with coronary heart disease after interventional therapy is better than that of traditional risk. FAR has higher sensitivity and specificity than FIB and Alb alone in predicting major cardiovascular adverse events, especially with DM. This paper aims to describe the relationship between TyG index, FIB/Alb ratio (FAR) and SII in the severity of coronary lesions in patients with AMI, so as to better understand the application value of TyG index, FIB/Alb ratio (FAR) and SII in AMI.展开更多
In order to contribute to a better understanding of the biodiversity of local chicken populations, this study focused on the description of the essential qualitative parameters in the phenotypic characterization of lo...In order to contribute to a better understanding of the biodiversity of local chicken populations, this study focused on the description of the essential qualitative parameters in the phenotypic characterization of local species. Conducted in 6 localities in the Far North Region of Cameroon (Doukoula, Yagoua, Guidiguis, Dziguilao, Maroua 3rd and Méri), a population of 240 local chickens, including 172 hens and 68 cocks were characterized in family farms. The choice of localities was made on the basis of their strong potential local chicken flocks in the region. To this end, each animal was the subject of a qualitative description based on the identification of the sex of the animal, the description of the colorations of the plumage and extremities, and the description of the types of format, plumage and crests. All observations were made with the naked eye and in daylight and then photographed. The main results show that the plumage colors are multiple and dominated by the White-Pied-Black (21.7%) and the Mille-fleur (20.8%);the wattles are dominated by the red (60%) and the pink (35.4%);the tarsi are dominated by the white (43.8%) and the black (32.08%);the white skin (92.5%) dominates over the pink skin (7.5%);the “Smooth-uniform” feather is dominant (97.08%), followed by the smooth-crested type (2.08%) and the fries type (0.82%);the medium size of the chickens is dominant (86.66%), followed by the dwarf size (9.58%) and the large size (3.75%). The results of this study demonstrate that there is a strong phenotypic diversity within the local chicken population. This diversity can serve as a basis for the development of selection, conservation and genetic potential improvement programs based on rational exploitation of the local chicken.展开更多
Vortex beams carrying orbital angular momentum(OAM)are of great significance for high-capacity communication and super-resolution imaging.However,there is a huge gap between the free-space vortices(FVs)and plasmonic v...Vortex beams carrying orbital angular momentum(OAM)are of great significance for high-capacity communication and super-resolution imaging.However,there is a huge gap between the free-space vortices(FVs)and plasmonic vortices(PVs)on chips,and active manipulation as well as multiplexing in more channels have become a pressing demand.In this work,we demonstrate a terahertz(THz)cascaded metadevice composed of a helical plasmonic metasurface,a liquid crystal(LC)layer,and a helical dielectric metasurface.By spin-orbital angular momentum coupling and photon state superposition,PVs and FVs are generated with mode purity of over 85%on average.Due to the inversion asymmetric design of the helical metasurfaces,the parity symmetry breaking of OAM is realized(the topological charge numbers no longer occur in positive and negative pairs,but all are positive),generating 6 independent channels associated with the decoupled spin states and the near-/far-field positions.Moreover,by the LC integration,dynamic mode switching and energy distribution can be realized,finally obtaining up to 12 modes with a modulation ratio of above 70%.This active tuning and multi-channel multiplexing metadevice establishes a bridge connection between the PVs and FVs,exhibiting promising applications in THz communication,intelligent perception,and information processing.展开更多
There is a gradual increase in the proportion of renewable energy sources.Green hydrogen has the potential to become one of the major energy carriers in the future.The Russian Federation,in partnership with countries ...There is a gradual increase in the proportion of renewable energy sources.Green hydrogen has the potential to become one of the major energy carriers in the future.The Russian Federation,in partnership with countries in the Asia-Pacific region and especially China,has the potential to play a significant role in green hydrogen market.This study assessed the potential of developing green hydrogen energy based on wind power in the Far Eastern Federal District(FEFD)of the Russian Federation.Empirical wind speed data were collected from 20 meteorological stations in 4 regions(Sakhalinskaya Oblast’,Primorskiy Krai,Khabarovskiy Krai,and Amurskaya Oblast’)of the FEFD.The Weibull distribution was used to predict the potential of green hydrogen production.Five different methods(Empirical Method of Justus(EMJ),Empirical Method of Lysen(EML),Maximum Likelihood Method(MLE),Power Density Method(PDM),and Median and Quartiles Method(MQM))were used to determine the parameters(scape factor and scale factor)of the Weibull distribution.We calculated the total electricity generation potential based on the technical specifications of the three wind turbines:Senvion 6150 onshore,H165-4.0 MW,and Vestas V150-4.2 MW.The results showed that Vladivostok,Pogibi,Ilyinskiy,Yuzhno-Kuril’sk,Severo-Kuril’sk,Kholmsk,and Okha stations had the higher potential of green hydrogen production,of which Vladivostok exhibited the highest potential of green hydrogen production using the wind turbine of H165-4.0 MW,up to 2.56×10^(5) kg/a.In terms of economic analysis,the levelized cost of hydrogen(LCOH)values of lower than 4.00 USD/kg were obtained at Yuzhno-Kuril’sk,Ilyinskiy,Pogibi,and Vladivostok stations using the wind turbine of H165-4.0 MW,with the values of 3.54,3.50,3.24,and 2.55 USD/kg,respectively.This study concluded that the FEFD possesses significant potential in the production of green hydrogen and,with appropriate investment,has the potential to become a significant hub for green hydrogen trading in the Asia-Pacific region.展开更多
This study identified the relationship between tropical cyclone(TC)activity and extreme Pacific–Japan(PJ)teleconnection patterns in August and September.In the East China Sea(ECS)and Mariana Islands(MI)regions,where ...This study identified the relationship between tropical cyclone(TC)activity and extreme Pacific–Japan(PJ)teleconnection patterns in August and September.In the East China Sea(ECS)and Mariana Islands(MI)regions,where the edge of the western North Pacific subtropical high(WNPSH)is located,approximately 60%–75%of TCs migrate to Far East Asian countries.A significant positive correlation existed between the frequency of northward migration of TCs and PJ patterns,since the TC frequency in the ECS and MI regions was significantly higher in the positive compared with the negative phase.In the positive phase,the main reason for the large number of TCs occurring was the monsoon trough’s location and strength.The strong and northeastward-shifted monsoon trough in the positive phase leads to more TCs in the ECS and MI regions.Other large-scale environments associated with TC formation also favored TC genesis around the ECS and MI regions.The higher PDI(power dissipation index)during the positive PJ phase can potentially lead to significant impacts in the Far East Asian countries.These characteristics were particularly more notable in August compared with September.展开更多
The FAR1-related sequence(FAR1)gene family consists of transcription factors that originated from transposases and is crucial for light signaling and stress adaptation in plants.Despite the recognized importance of FA...The FAR1-related sequence(FAR1)gene family consists of transcription factors that originated from transposases and is crucial for light signaling and stress adaptation in plants.Despite the recognized importance of FAR1 genes in model organisms,their genomic architecture,structural variability,and expression patterns in Phaseolus vulgaris have yet to be investigated.This study offers the inaugural comprehensive genome-wide identification and characterization of the FAR1 gene family in P.vulgaris.A total of 27 PvulFAR1 genes were identified,and their chromosomal distribution,gene structures,conserved domains,and phylogenetic relationships were analyzed systematically.The promoter regions of these genes were discovered to encompass a diverse range of cis-regulatory elements that respond to light,phytohormones,and abiotic stressors,highlighting their regulatory complexity.In silico expression analysis and quantitative real-time PCR(qRT-PCR)experiments demonstrated differential expression patterns of specific PvulFAR1 genes under salt and drought stress in two commercial bean cultivars.PvulFAR1-10 demonstrated consistent upregulation under both stress conditions,especially in the stress-tolerant cultivar Elkoca-05,indicating its potential role in broad-spectrum stress responsiveness.Gene ontology and protein–protein interaction network analyses revealed that PvulFAR1 proteins are predominantly nuclear-localized transcription factors,enriched in zinc ion binding activity,and associated with transcriptional regulation and nucleobase metabolic processes.The results offer novel perspectives on the evolution,structural complexity,and stress-responsive regulatory functions of the FAR1 gene family in common bean.This fundamental knowledge provides significant candidate genes for additional validation and for developing of genetically improved cultivars with enhanced tolerance to abiotic stresses.Future research should focus on clarifying the downstream targets of essential FAR1 members and their integrative function in plant developmental and stress response networks.展开更多
BACKGROUND Far lateral lumbar disc herniation(FLLDH)is a special type of lumbar disc herniation with high rate of missed diagnosis.Selective nerve root block(SNRB)has special advantages in identifying the responsible ...BACKGROUND Far lateral lumbar disc herniation(FLLDH)is a special type of lumbar disc herniation with high rate of missed diagnosis.Selective nerve root block(SNRB)has special advantages in identifying the responsible nerve root.Percutaneous transforaminal endoscopic discectomy(PTED)is a minimally invasive and effective method to treat FLLDH.However,no report has investigated PTED combined with SNRB to treat FLLDH.AIM To explore the diagnosis and treatment process,surgical technique and clinical efficacy of PTED combined with SNRB to treat FLLDH.METHODS This is a multicenter center,retrospective,observational study.Between January 2020 and January 2022,32 patients were initially diagnosed with FLLDH.All the patients were identified using SNRB to determine the responsible segment and involved nerve roots.Because of poor symptomatic control following SNRB,2 patients were excluded.30 patients diagnosed with FFLDH underwent PTED.The clinical characteristics,operative and postoperative outcomes,complication and subsequent follow-up were collected.RESULTS 30 patients who underwent SNRB combined with PTED were followed up.The average visual analogue scale(VAS)-leg score,VAS-back score,Oswestry disability index(ODI)score at the Follow-up(1 day,1 month,3 months and last follow-up)were significantly different compared per-operation.According to the modified Macnab efficacy evaluation standard,the satisfaction degree at the last follow-up was excellent(28,93.33%),good(1,3.33%),medium(1,3.33%)and poor(0,0%).CONCLUSION SNRB provides an effective method for the definite diagnosis of FLDH and responsible nerve roots.Combination therapy offers several advantages including minimal invasiveness,precision,effectiveness,safety and low recurrence rates.展开更多
目的 探讨血清纤维蛋白原与白蛋白比值(Fibrinogen to Albumin Ratio,FAR)联合单核细胞/高密度脂蛋白胆固醇比值(Monocyte to High-density Lipoprotein Cholesterol Ratio,MHR)对急性冠状动脉综合征经皮冠状动脉介入治疗(Percutaneous ...目的 探讨血清纤维蛋白原与白蛋白比值(Fibrinogen to Albumin Ratio,FAR)联合单核细胞/高密度脂蛋白胆固醇比值(Monocyte to High-density Lipoprotein Cholesterol Ratio,MHR)对急性冠状动脉综合征经皮冠状动脉介入治疗(Percutaneous Coronary Interventi,PCI)术后患者再发不良心血管事件的预测价值。方法 选取2022年10月至2023年5月罗源县医院心血管内科收治的126例急性冠状动脉综合征患者作为本次研究对象,根据两组患者PCI术后随访1年内是否再发不良心血管事件分为发生组(37例)和未发生组(89例)。收集两组患者的临床资料,对比两组患者一般资料及实验室指标,采用多因素Logistic回归分析急性冠状动脉综合征患者再发不良心血管事件的影响因素,采用受试者工作特征(ROC)曲线分析血清FAR、MHR及二者联合对急性冠状动脉综合征患者再发不良心血管事件的预测价值。结果 发生组患者年龄、FIB、FAR、单核细胞计数、MHR均高于对照组,比较差异有统计学意义(P<0.05);多因素Logistic回归分析显示,FAR、MHR是急性冠状动脉综合征患者再发不良心血管事件的独立影响因素,差异有统计学意义(P<0.05);FAR、MHR对急性冠状动脉综合征患者再发不良心血管事件均有预测价值,其中FAR、MHR联合预测指标预测急性冠状动脉综合征患者再发不良心血管事件的效能最高(AUC=0.896,95%CI为0.839-0.952)。结论 血清FAR联合MHR预测急性冠状动脉综合征患者再发不良心血管事件价值高于血清FAR、MHR单独预测价值,为急性冠状动脉综合征患者再发不良心血管事件的早期预测提供了重要参考。展开更多
文摘心血管疾病(cardiovascular disease, CVD)是全球发病率和死亡率的主要原因,严重威胁着全球人类的健康。CVD包含疾病有多种其中急性心肌梗死(AMI)是最常见严重危害中老年人群健康的心血管疾病之一,血清甘油三酯葡萄糖指数(triglyceride-glucose index, TyG指数)是胰岛素抵抗(insulin resistance, IR)的一种新型替代指标,为条件受限地区临床决策提供有力依据。有研究指出TyG指数不仅可预测CVD、2型糖尿病的发生发展,还可评估代谢性疾病发生。SII对冠心病患者介入治疗后发生不良心血管事件的预测价值优于传统危险。FAR在预测主要心血管不良事件尤其是合并DM方面比单独用FIB和Alb有更高敏感性和特异性。本文旨在阐述TyG指数与FIB/Alb比值(FAR)、SII在AMI患者中冠脉病变严重程度的发生发展关系,以便更好地了解TyG指数、FIB/Alb比值(FAR)、SII在AMI中的应用价值。Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide and poses a serious threat to human health worldwide. CVD includes a variety of diseases, among which acute myocardial infarction (AMI) is one of the most common cardiovascular diseases that seriously harm the health of middle-aged and elderly people. Serum triglyceride-glucose index (TyG index) is a novel proxy for insulin resistance (IR), which provides a strong basis for clinical decision-making in restricted areas. Some studies have pointed out that TyG index can not only predict the occurrence and development of CVD and type 2 diabetes, but also evaluate the occurrence of metabolic diseases. The predictive value of SII for adverse cardiovascular events in patients with coronary heart disease after interventional therapy is better than that of traditional risk. FAR has higher sensitivity and specificity than FIB and Alb alone in predicting major cardiovascular adverse events, especially with DM. This paper aims to describe the relationship between TyG index, FIB/Alb ratio (FAR) and SII in the severity of coronary lesions in patients with AMI, so as to better understand the application value of TyG index, FIB/Alb ratio (FAR) and SII in AMI.
文摘In order to contribute to a better understanding of the biodiversity of local chicken populations, this study focused on the description of the essential qualitative parameters in the phenotypic characterization of local species. Conducted in 6 localities in the Far North Region of Cameroon (Doukoula, Yagoua, Guidiguis, Dziguilao, Maroua 3rd and Méri), a population of 240 local chickens, including 172 hens and 68 cocks were characterized in family farms. The choice of localities was made on the basis of their strong potential local chicken flocks in the region. To this end, each animal was the subject of a qualitative description based on the identification of the sex of the animal, the description of the colorations of the plumage and extremities, and the description of the types of format, plumage and crests. All observations were made with the naked eye and in daylight and then photographed. The main results show that the plumage colors are multiple and dominated by the White-Pied-Black (21.7%) and the Mille-fleur (20.8%);the wattles are dominated by the red (60%) and the pink (35.4%);the tarsi are dominated by the white (43.8%) and the black (32.08%);the white skin (92.5%) dominates over the pink skin (7.5%);the “Smooth-uniform” feather is dominant (97.08%), followed by the smooth-crested type (2.08%) and the fries type (0.82%);the medium size of the chickens is dominant (86.66%), followed by the dwarf size (9.58%) and the large size (3.75%). The results of this study demonstrate that there is a strong phenotypic diversity within the local chicken population. This diversity can serve as a basis for the development of selection, conservation and genetic potential improvement programs based on rational exploitation of the local chicken.
基金supported by the National Natural Science Foundation of China(62335012,62371258,624B2075,62205160,62435010)Young Scientific and Technological Talents in Tianjin(QN20230227)Fundamental Research Funds for the Central Universities,Nankai University(63231159).
文摘Vortex beams carrying orbital angular momentum(OAM)are of great significance for high-capacity communication and super-resolution imaging.However,there is a huge gap between the free-space vortices(FVs)and plasmonic vortices(PVs)on chips,and active manipulation as well as multiplexing in more channels have become a pressing demand.In this work,we demonstrate a terahertz(THz)cascaded metadevice composed of a helical plasmonic metasurface,a liquid crystal(LC)layer,and a helical dielectric metasurface.By spin-orbital angular momentum coupling and photon state superposition,PVs and FVs are generated with mode purity of over 85%on average.Due to the inversion asymmetric design of the helical metasurfaces,the parity symmetry breaking of OAM is realized(the topological charge numbers no longer occur in positive and negative pairs,but all are positive),generating 6 independent channels associated with the decoupled spin states and the near-/far-field positions.Moreover,by the LC integration,dynamic mode switching and energy distribution can be realized,finally obtaining up to 12 modes with a modulation ratio of above 70%.This active tuning and multi-channel multiplexing metadevice establishes a bridge connection between the PVs and FVs,exhibiting promising applications in THz communication,intelligent perception,and information processing.
文摘There is a gradual increase in the proportion of renewable energy sources.Green hydrogen has the potential to become one of the major energy carriers in the future.The Russian Federation,in partnership with countries in the Asia-Pacific region and especially China,has the potential to play a significant role in green hydrogen market.This study assessed the potential of developing green hydrogen energy based on wind power in the Far Eastern Federal District(FEFD)of the Russian Federation.Empirical wind speed data were collected from 20 meteorological stations in 4 regions(Sakhalinskaya Oblast’,Primorskiy Krai,Khabarovskiy Krai,and Amurskaya Oblast’)of the FEFD.The Weibull distribution was used to predict the potential of green hydrogen production.Five different methods(Empirical Method of Justus(EMJ),Empirical Method of Lysen(EML),Maximum Likelihood Method(MLE),Power Density Method(PDM),and Median and Quartiles Method(MQM))were used to determine the parameters(scape factor and scale factor)of the Weibull distribution.We calculated the total electricity generation potential based on the technical specifications of the three wind turbines:Senvion 6150 onshore,H165-4.0 MW,and Vestas V150-4.2 MW.The results showed that Vladivostok,Pogibi,Ilyinskiy,Yuzhno-Kuril’sk,Severo-Kuril’sk,Kholmsk,and Okha stations had the higher potential of green hydrogen production,of which Vladivostok exhibited the highest potential of green hydrogen production using the wind turbine of H165-4.0 MW,up to 2.56×10^(5) kg/a.In terms of economic analysis,the levelized cost of hydrogen(LCOH)values of lower than 4.00 USD/kg were obtained at Yuzhno-Kuril’sk,Ilyinskiy,Pogibi,and Vladivostok stations using the wind turbine of H165-4.0 MW,with the values of 3.54,3.50,3.24,and 2.55 USD/kg,respectively.This study concluded that the FEFD possesses significant potential in the production of green hydrogen and,with appropriate investment,has the potential to become a significant hub for green hydrogen trading in the Asia-Pacific region.
基金the Korea Meteorological Administration Research and Development Program under Grant KMI(Grant No.RS-2023-00241809)conducted under the framework of the research and development program of the Korea Institute of Energy Research(C5-2422).
文摘This study identified the relationship between tropical cyclone(TC)activity and extreme Pacific–Japan(PJ)teleconnection patterns in August and September.In the East China Sea(ECS)and Mariana Islands(MI)regions,where the edge of the western North Pacific subtropical high(WNPSH)is located,approximately 60%–75%of TCs migrate to Far East Asian countries.A significant positive correlation existed between the frequency of northward migration of TCs and PJ patterns,since the TC frequency in the ECS and MI regions was significantly higher in the positive compared with the negative phase.In the positive phase,the main reason for the large number of TCs occurring was the monsoon trough’s location and strength.The strong and northeastward-shifted monsoon trough in the positive phase leads to more TCs in the ECS and MI regions.Other large-scale environments associated with TC formation also favored TC genesis around the ECS and MI regions.The higher PDI(power dissipation index)during the positive PJ phase can potentially lead to significant impacts in the Far East Asian countries.These characteristics were particularly more notable in August compared with September.
文摘The FAR1-related sequence(FAR1)gene family consists of transcription factors that originated from transposases and is crucial for light signaling and stress adaptation in plants.Despite the recognized importance of FAR1 genes in model organisms,their genomic architecture,structural variability,and expression patterns in Phaseolus vulgaris have yet to be investigated.This study offers the inaugural comprehensive genome-wide identification and characterization of the FAR1 gene family in P.vulgaris.A total of 27 PvulFAR1 genes were identified,and their chromosomal distribution,gene structures,conserved domains,and phylogenetic relationships were analyzed systematically.The promoter regions of these genes were discovered to encompass a diverse range of cis-regulatory elements that respond to light,phytohormones,and abiotic stressors,highlighting their regulatory complexity.In silico expression analysis and quantitative real-time PCR(qRT-PCR)experiments demonstrated differential expression patterns of specific PvulFAR1 genes under salt and drought stress in two commercial bean cultivars.PvulFAR1-10 demonstrated consistent upregulation under both stress conditions,especially in the stress-tolerant cultivar Elkoca-05,indicating its potential role in broad-spectrum stress responsiveness.Gene ontology and protein–protein interaction network analyses revealed that PvulFAR1 proteins are predominantly nuclear-localized transcription factors,enriched in zinc ion binding activity,and associated with transcriptional regulation and nucleobase metabolic processes.The results offer novel perspectives on the evolution,structural complexity,and stress-responsive regulatory functions of the FAR1 gene family in common bean.This fundamental knowledge provides significant candidate genes for additional validation and for developing of genetically improved cultivars with enhanced tolerance to abiotic stresses.Future research should focus on clarifying the downstream targets of essential FAR1 members and their integrative function in plant developmental and stress response networks.
基金Supported by the National Key R&D Program of China,No.Key Special Project for Marine Environmental Security and Sustainable Development of Coral Reefs 2022-3.5the National Natural Science Foundation of China,No.82102605,82472458,and 82272533.
文摘BACKGROUND Far lateral lumbar disc herniation(FLLDH)is a special type of lumbar disc herniation with high rate of missed diagnosis.Selective nerve root block(SNRB)has special advantages in identifying the responsible nerve root.Percutaneous transforaminal endoscopic discectomy(PTED)is a minimally invasive and effective method to treat FLLDH.However,no report has investigated PTED combined with SNRB to treat FLLDH.AIM To explore the diagnosis and treatment process,surgical technique and clinical efficacy of PTED combined with SNRB to treat FLLDH.METHODS This is a multicenter center,retrospective,observational study.Between January 2020 and January 2022,32 patients were initially diagnosed with FLLDH.All the patients were identified using SNRB to determine the responsible segment and involved nerve roots.Because of poor symptomatic control following SNRB,2 patients were excluded.30 patients diagnosed with FFLDH underwent PTED.The clinical characteristics,operative and postoperative outcomes,complication and subsequent follow-up were collected.RESULTS 30 patients who underwent SNRB combined with PTED were followed up.The average visual analogue scale(VAS)-leg score,VAS-back score,Oswestry disability index(ODI)score at the Follow-up(1 day,1 month,3 months and last follow-up)were significantly different compared per-operation.According to the modified Macnab efficacy evaluation standard,the satisfaction degree at the last follow-up was excellent(28,93.33%),good(1,3.33%),medium(1,3.33%)and poor(0,0%).CONCLUSION SNRB provides an effective method for the definite diagnosis of FLDH and responsible nerve roots.Combination therapy offers several advantages including minimal invasiveness,precision,effectiveness,safety and low recurrence rates.
文摘目的 探讨血清纤维蛋白原与白蛋白比值(Fibrinogen to Albumin Ratio,FAR)联合单核细胞/高密度脂蛋白胆固醇比值(Monocyte to High-density Lipoprotein Cholesterol Ratio,MHR)对急性冠状动脉综合征经皮冠状动脉介入治疗(Percutaneous Coronary Interventi,PCI)术后患者再发不良心血管事件的预测价值。方法 选取2022年10月至2023年5月罗源县医院心血管内科收治的126例急性冠状动脉综合征患者作为本次研究对象,根据两组患者PCI术后随访1年内是否再发不良心血管事件分为发生组(37例)和未发生组(89例)。收集两组患者的临床资料,对比两组患者一般资料及实验室指标,采用多因素Logistic回归分析急性冠状动脉综合征患者再发不良心血管事件的影响因素,采用受试者工作特征(ROC)曲线分析血清FAR、MHR及二者联合对急性冠状动脉综合征患者再发不良心血管事件的预测价值。结果 发生组患者年龄、FIB、FAR、单核细胞计数、MHR均高于对照组,比较差异有统计学意义(P<0.05);多因素Logistic回归分析显示,FAR、MHR是急性冠状动脉综合征患者再发不良心血管事件的独立影响因素,差异有统计学意义(P<0.05);FAR、MHR对急性冠状动脉综合征患者再发不良心血管事件均有预测价值,其中FAR、MHR联合预测指标预测急性冠状动脉综合征患者再发不良心血管事件的效能最高(AUC=0.896,95%CI为0.839-0.952)。结论 血清FAR联合MHR预测急性冠状动脉综合征患者再发不良心血管事件价值高于血清FAR、MHR单独预测价值,为急性冠状动脉综合征患者再发不良心血管事件的早期预测提供了重要参考。
