Fangjiomics is a promising paradigm that enhances research on multi-omics-based pharmacological mechanisms of Fangji from holistic and systematic perspective.We reviewed recent advances in Fangjiomics,focusing on data...Fangjiomics is a promising paradigm that enhances research on multi-omics-based pharmacological mechanisms of Fangji from holistic and systematic perspective.We reviewed recent advances in Fangjiomics,focusing on database and analysis platform development,methodological innovations,and translational applications.Through the integration of Fangji and multi-omics data,multi-level system analysis approaches were developed,encompassing single-target analysis,signaling pathways,multi-targeted network and modules.Fangjiomics has emerged as a key strategy in various areas of Fangji research.To support the high quality development of Fangjiomics,we propose principles and perspectives from the integrated,macro-level,and practical viewpoints.展开更多
基金National Key Research and Development Project(2023YFC3502903)National Natural Science Foundation of China(82474376)Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(CI2023C063YLL).
文摘Fangjiomics is a promising paradigm that enhances research on multi-omics-based pharmacological mechanisms of Fangji from holistic and systematic perspective.We reviewed recent advances in Fangjiomics,focusing on database and analysis platform development,methodological innovations,and translational applications.Through the integration of Fangji and multi-omics data,multi-level system analysis approaches were developed,encompassing single-target analysis,signaling pathways,multi-targeted network and modules.Fangjiomics has emerged as a key strategy in various areas of Fangji research.To support the high quality development of Fangjiomics,we propose principles and perspectives from the integrated,macro-level,and practical viewpoints.
