Solid-state electrolytes(SSEs),as the core component within the next generation of key energy storage technologies-solid-state lithium batteries(SSLBs)-are significantly leading the development of future energy storag...Solid-state electrolytes(SSEs),as the core component within the next generation of key energy storage technologies-solid-state lithium batteries(SSLBs)-are significantly leading the development of future energy storage systems.Among the numerous types of SSEs,inorganic oxide garnet-structured superionic conductors Li7La3Zr2O12(LLZO)crystallized with the cubic Iaˉ3d space group have received considerable attention owing to their highly advantageous intrinsic properties encompassing reasonable lithium-ion conductivity,wide electrochemical voltage window,high shear modulus,and excellent chemical stability with electrodes.However,no SSEs possess all the properties necessary for SSLBs,thus both the ionic conductivity at room temperature and stability in ambient air regarding cubic garnet-based electrolytes are still subject to further improvement.Hence,this review comprehensively covers the nine key structural factors affecting the ion conductivity of garnet-based electrolytes comprising Li concentration,Li vacancy concentration,Li carrier concentration and mobility,Li occupancy at available sites,lattice constant,triangle bottleneck size,oxygen vacancy defects,and Li-O bonding interactions.Furthermore,the general illustration of structures and fundamental features being crucial to chemical stability is examined,including Li concentration,Li-site occupation behavior,and Li-O bonding interactions.Insights into the composition-structure-property relations among cubic garnet-based oxide ionic conductors from the perspective of their crystal structures,revealing the potential compatibility conflicts between ionic transportation and chemical stability resulting from Li-O bonding interactions.We believe that this review will lay the foundation for future reasonable structural design of oxide-based or even other types of superionic conductors,thus assisting in promoting the rapid development of alternative green and sustainable technologies.展开更多
[Objective] This study aimed to analyze the influence of five cultivation factors： sowing date, plant density, nitrogen fertilizer amount, phosphate fertilizer amount and potash fertilizer amount on oil quality and ...[Objective] This study aimed to analyze the influence of five cultivation factors： sowing date, plant density, nitrogen fertilizer amount, phosphate fertilizer amount and potash fertilizer amount on oil quality and stability of Brassica napus hybrids. [Method] Statistical analysis was carried out based on the data from previous studies and our work. [Result] Sowing date had no significant influence on oil quality and stability of B. napus hybrids. The plant density shared a positive correlation with 18-C fatty acid （FA） content, unsaturated fatty acid （UFA） content, total content of linoleic acid and linolenic acid, index of unsaturated fatty acid （IUFA）, so a large plant density can improve the oil quality （by increasing18-C FA content, UFA content, total content of linoleic acid and linolenic acid）, but reduce the oil stability （by increasing IUFA）. The amount of nitrogen fertilizer had no significant influence on the contents of 18-C FA and UFA, but significant positive correlations with the total content of linoleic acid and linolenic acid and IUFA. So, the total content of linoleic acid and linolenic acid can be reduced by increasing nitrogen amount, meanwhile the oil stability was also decreased. Phosphate fertilizer amount did not affect 18-C FA significantly, but was negatively correlated with the UFA content, total content of linoleic acid and linolenic acid, and IUFA. So, increasing the amount of applied phosphate fertilizer can reduce UFA content, total content of linoleic acid and linolenic acid, thereby improving oil stability. Potash fertilizer had no significant influence on the IUFA, a significant positive correlation with 18-C FA content, an insignificant positive correlation with the the UFA content, and a negative correlation with the total content of linoleic acid and linolenic acid. The oil content of rapeseed shared an extremely significant positive correlation with 18-C FA content and UFA content, an negative correlation with the total content of linoleic acid and linolenic acid, and no significant correlation with IUFA. [Conclusion] This study identified the effects of five main cultivation factors on oil quality and stability of B. napus hybrids, and the correlations of oil content with 18-C FA content, UFA content, total content of linoleic acid and linolenic acid, and IUFA.展开更多
Dorsal root ganglia neurons gradually lose their axonal regeneration ability during development and aging.To explore molecules that enhance axonal regeneration,we screened growth factors with differential gene express...Dorsal root ganglia neurons gradually lose their axonal regeneration ability during development and aging.To explore molecules that enhance axonal regeneration,we screened growth factors with differential gene expression patterns in the dorsal root ganglias of young adult and aged animals following sciatic nerve injury.In young adult animals,two transforming growth factor beta-related factors,activin A and angiopoietin 2,were found to be upregulated post nerve injury.Treatment of isolated dorsal root ganglia explants and cultured dorsal root ganglia neurons of neonatal and young adult rats with recombinant activin A or angiopoietin 2 protein stimulated neurite outgrowth and axonal elongation.The administration of recombinant activin A or angiopoietin 2 protein to sciatic nerve crush-injured dorsal root ganglias also supported the growth of sensory neurons and facilitated nerve regeneration in both young adult and aged rats.Using RNA sequencing,we characterized genetic changes in dorsal root ganglia neurons following recombinant activin A or angiopoietin 2 treatment,revealing the unique mechanisms of these transforming growth factor beta-related factors.Recombinant activin A elicited changes in the gene expression of cytoskeleton-related Gper1 and activated extracellular signal-regulated kinase signaling,while angiopoietin 2 increased the expression of the transcription factor gene E2f2.Our identification of activin A and angiopoietin 2 as crucial promotional factors of axonal regeneration may guide future therapeutic strategies for the treatment of nerve injury.展开更多
The paper considers the methodology for a comprehensive analysis of the stability of an open pit-dump system,using limit equilibrium(LEM)and finite element(FEM)methods in the Russian CAE(computer-aided engineering)sof...The paper considers the methodology for a comprehensive analysis of the stability of an open pit-dump system,using limit equilibrium(LEM)and finite element(FEM)methods in the Russian CAE(computer-aided engineering)software Fidesys.It briefly highlights the issues of comparing limit equilibrium methods using the VNIMI(Research Institute of Geomechanics and Mine Surveying-Intersectoral Scientific Center"VNIMI")methodology and a specialized software product with numerical methods.The main focus of this study is to compare the results of the stability analysis in the volumetric model of the open pit-dump system using limit equilibrium and finite element methods in the CAE software Fidesys.It was found that,when modeling the combined operation of an open pit-dump system in complex terrain,both methods should be used,as each has its own advantages.The finite element method,for instance,has certain features that are not present in the calculations using the limit equilibrium approach.As a key scientific contribution,this paper introduces an automation program for calculating the stability of open-pit walls using the limit equilibrium method in CAE Fidesys,which was not previously integrated in the original software.The calculations performed with the use of this newly developed module were compared to those obtained from other widely used software solutions available on the market.The findings demonstrate a remarkable level of convergence in the calculation results for all relevant parameters,including the safety factor,localization,instability type,and deformation.The proposed approach i mproves the accuracy of calculati ons and ensures consistency between the higher stress design zones and the actual deformation and fracture patterns.It also enhances the ability to predict the behavior of rock mass when calculating stability parameters for facilities,both during operation and desi gn.展开更多
When the slope is in critical limit equilibrium(LE) state, the strength parameters have different contribution to each other on maintaining slope stability. That is to say that the strength parameters are not simultan...When the slope is in critical limit equilibrium(LE) state, the strength parameters have different contribution to each other on maintaining slope stability. That is to say that the strength parameters are not simultaneously reduced. Hence, the LE stress method is established to analyze the slope stability by employing the double strengthreduction(DSR) technique in this work. For calculation model of slope stability under the DSR technique, the general nonlinear Mohr–Coulomb(M–C) criterion is used to describe the shear failure of slope. Meanwhile, the average and polar diameter methods via the DSR technique are both adopted to calculate the comprehensive factor of safety(FOS) of slope. To extend the application of the polar diameter method, the original method is improved in the proposed method. After comparison and analysis on some slope examples, the proposed method's feasibility is verified. Thereafter, the stability charts of slope suitable for engineering application are drawn. Moreover, the studies show that:(1) the average method yields similar results as that of the polardiameter method;(2) compared with the traditional uniform strength-reduction(USR) technique, the slope stability obtained using the DSR techniquetends to be more unsafe; and(3) for a slope in the critical LE state, the strength parameter φ, i.e., internal friction angle, has greater contribution on the slope stability than the strength parameters c, i.e., cohesion.展开更多
The evaluation of the seismic stability of an expanded municipal solid waste(MSW) landfill is very important in seismic prone zones.In this paper,the pseudo-dynamic method was used to calculate the average safety fact...The evaluation of the seismic stability of an expanded municipal solid waste(MSW) landfill is very important in seismic prone zones.In this paper,the pseudo-dynamic method was used to calculate the average safety factor for the expanded landfill with a trapezoidal berm based on under-berm failure conditions.Furthermore,the effects of the variation of parameters such as the amplification factor,seismic coefficient,height of berm,angle of back slope of berm,and depth of waste mass at the back slope on the seismic stability of the landfill were studied.The results indicated that the influences of the vertical seismic coefficient,height of berm,and angle of the back slope of the berm on the seismic stability of the landfill are weakened as the amplification factor increases,but the influence of the horizontal seismic coefficient on the seismic stability of the landfill is strengthened.On the other hand,a certain ratio of the height of the waste mass above the back slope to the depth of waste mass at the back slope,or the reasonable consideration of the magnitude of the amplification factor will be conducive to the seismic design of the landfill.In addition,the results obtained by the pseudo-static and pseudo-dynamic methods were compared.展开更多
Unlike the limit equilibrium method(LEM), with which only the global safety factor of the landslide can be calculated, a local safety factor(LSF) method is proposed to evaluate the stability of different sections of a...Unlike the limit equilibrium method(LEM), with which only the global safety factor of the landslide can be calculated, a local safety factor(LSF) method is proposed to evaluate the stability of different sections of a landslide in this paper. Based on three-dimensional(3D) numerical simulation results, the local safety factor is defined as the ratio of the shear strength of the soil at an element on the slip zone to the shear stress parallel to the sliding direction at that element. The global safety factor of the landslide is defined as the weighted average of all local safety factors based on the area of the slip surface. Some example analyses show that the results computed by the LSF method agree well with those calculated by the General Limit Equilibrium(GLE) method in two-dimensional(2D) models and the distribution of the LSF in the 3D slip zone is consistent with that indicated by the observed deformation pattern of an actual landslide in China.展开更多
Deep beam anchorage structures based on spatial distribution analysis of the cable prestressed field have been proposed for roadway roof support, Stability and other factors that influence deep beam structures are stu...Deep beam anchorage structures based on spatial distribution analysis of the cable prestressed field have been proposed for roadway roof support, Stability and other factors that influence deep beam structures are studied in this paper using mechanical calculations, numerical analysis and field measurements, A mechanical model of deep beam structure subjected to multiple loading is established, including analysis of roof support in the return airway of S1203 working face in the Yuwu coal mine, China, The expression of maximum shear stress in the deep beam structure is deduced according to the stress superposition criterion, It is found that the primary factors affecting deep beam structure stability are deep beam thickness, cable pre-tension and cable spacing, The variation of maximum shear stress distribution and prestressed field diffusion effects according to various factors are analyzed using Matlah and FLAC3DTM software, and practical support parameters of the S1203 return airway roof are determined, According to the observations of rock pressure, there is no evidence of roof separation, and the maximum values of roof subsidence and convergence of wall rock are 72 and 48 mm, respectively, The results show that the proposed roof support design with a deep beam structure is feasible and achieves effective control of the roadway roof,展开更多
The prediction of slope stability is a complex nonlinear problem.This paper proposes a new method based on the random forest(RF)algorithm to study the rocky slopes stability.Taking the Bukit Merah,Perak and Twin Peak(...The prediction of slope stability is a complex nonlinear problem.This paper proposes a new method based on the random forest(RF)algorithm to study the rocky slopes stability.Taking the Bukit Merah,Perak and Twin Peak(Kuala Lumpur)as the study area,the slope characteristics of geometrical parameters are obtained from a multidisciplinary approach(consisting of geological,geotechnical,and remote sensing analyses).18 factors,including rock strength,rock quality designation(RQD),joint spacing,continuity,openness,roughness,filling,weathering,water seepage,temperature,vegetation index,water index,and orientation,are selected to construct model input variables while the factor of safety(FOS)functions as an output.The area under the curve(AUC)value of the receiver operating characteristic(ROC)curve is obtained with precision and accuracy and used to analyse the predictive model ability.With a large training set and predicted parameters,an area under the ROC curve(the AUC)of 0.95 is achieved.A precision score of 0.88 is obtained,indicating that the model has a low false positive rate and correctly identifies a substantial number of true positives.The findings emphasise the importance of using a variety of terrain characteristics and different approaches to characterise the rock slope.展开更多
To make grain price stable is an important goal for the Chinese government. The paper compared the grain supply elasticity and demand elasticity to determine the grain price stability in China; used ＂k value＂ method...To make grain price stable is an important goal for the Chinese government. The paper compared the grain supply elasticity and demand elasticity to determine the grain price stability in China; used ＂k value＂ method to analyze the grain price fluctuation from 1985 to 2010; divided the grain price volatility into three stages; and analyzed the factors in each phase. On the base, it put forward some countermeasures to guarantee the stability of the grain price.展开更多
When the bridge structure stability safety factor of the first type is 4, the research that whether the structure reliability index will reach target reliability index under the more-likely-to-happen collapse situatio...When the bridge structure stability safety factor of the first type is 4, the research that whether the structure reliability index will reach target reliability index under the more-likely-to-happen collapse situation of the second type is necessary. The stability calculations of the first and the second type are made respectively for single layer and single span rigid frame bridge. Based on the critical load obtained from the stability calculation of the first type, the stability safety factor of the first type is taken as 4, and the first order reliability method is used to program and calculate the reliability index. Then, the load effect under the stability reliability index cal- culation of the first type and the critical load of the second type are employed to calculate the reliability index of the second type. The evaluation of structure stability safety factor is discussed according to reliability index. Based on the discussion above, parameter analysis of the stable critical loads of two types is made, and the in- fluence of critical load change on reliability index is researched. The result shows that stability analysis should identify collapse state; when the stability safety factor of the first type is 4, but the structure has the collapse of the second type, the reliability index cannot be ensured to reach the target reliability index under certain condi- tions.展开更多
Here,we provide data suggesting that the absence of silencing of the ectopic reprogramming factors used to reprogram somatic cells to induced pluripotent stem cells(iPSCs)may predispose iPSCs to genomic instability.We...Here,we provide data suggesting that the absence of silencing of the ectopic reprogramming factors used to reprogram somatic cells to induced pluripotent stem cells(iPSCs)may predispose iPSCs to genomic instability.We encourage stem cell scientists to undertake an extensive characterization and standardization of much larger cohorts of iPSC lines in order to set up rigorous criteria to define safe and stable bonafide iPSCs.展开更多
The effect of controlling strata movement in solid filling mining depends on the filling rate of the goal. However, the mechanical property of the overburden in the backfill stope and the designed size of the backfill...The effect of controlling strata movement in solid filling mining depends on the filling rate of the goal. However, the mechanical property of the overburden in the backfill stope and the designed size of the backfill mining workface should also be considered. In this study, we established a main roof strata model with loads in accordance with the theory of key strata to investigate the stability of the overburden in solid dense filling mining. We analyzed the stress distribution law of the main roof strata based on elastic thin plate theory. The results show that the position of the long side midpoint of the main roof strata failed more easily because of tensile yield, indicating that this position is the area where failure is likely to occur more easily. We also deduced the stability mechanics criterion of the main roof strata based on tensile yield criterion. The factors affecting the stability of the overburden in solid dense filling mining were also analyzed, including the thickness and elasticity modulus of the main roof strata, overlying strata loads, advanced distance and length of workface, and elastic foundation coefficient of backfill body. The research achievements can provide an important theoretical basis for determining the designed size of the solid dense filling mining workface.展开更多
The southern forest ecosystem of Cameroon extends from latitude 2° to 6°N and from 10° to 16°E. In order to investigate about the influence of climate factors on the infrastructures, the main param...The southern forest ecosystem of Cameroon extends from latitude 2° to 6°N and from 10° to 16°E. In order to investigate about the influence of climate factors on the infrastructures, the main parameters of local climate of that ecosystem have been evaluated. The results show that, the factors are stable and have a common trend. But, the abundance of precipitations;the important hydrographic network and the presence of dense forest appear as the majors climatic constraints that may be taken in account to ensure the stability of the infrastructures in forest ecosystem.展开更多
Light is an environmental signaling,whereas Aux/IAA proteins and Auxin Response Factors(ARFs)are regulators of auxin signalling.Aux/IAA proteins are unstable,and their degradation dependents on 26S ubiquitin-proteasom...Light is an environmental signaling,whereas Aux/IAA proteins and Auxin Response Factors(ARFs)are regulators of auxin signalling.Aux/IAA proteins are unstable,and their degradation dependents on 26S ubiquitin-proteasome and is promoted by Auxin.Auxin binds directly to a SCF-type ubiquitin-protein ligase,TIR1,facilitates the interaction between Aux/IAA proteins and TIR1,and then the degradation of Aux/IAA proteins.A few studies have reported that some ARFs are also unstable proteins,and their degradation is also mediated by 26S proteasome.In this study,by using of antibodies recognizing endogenous ARF7 proteins,we found that protein stability of ARF7 was affected by light.By expressing MYC tagged ARF activators in protoplasts,we found that degradation of ARF7 was inhibited by 26 proteasome inhibitors.In addition,at least ARF5 and ARF19 were also unstable proteins,and degradation of ARF5 via 26S proteasome was further confirmed by using stable transformed plants overexpressing ARF5 with a GUS tag.展开更多
Objective: To investigate the correlation of coronary CTA calcification score (CACS) with serum inflammatory factors and plaque stability-related indexes in patients with coronary heart disease. Methods: A total of 22...Objective: To investigate the correlation of coronary CTA calcification score (CACS) with serum inflammatory factors and plaque stability-related indexes in patients with coronary heart disease. Methods: A total of 228 patients with possible coronary heart disease who were examined in this hospital between November 2014 and March 2017 were selected, and the CACS levels as well as the serum contents of inflammatory factors and plaque stability indexes in patients with different lesions were determined. Pearson test was used to assess the correlation between CACS level and disease severity in patients with coronary heart disease. Results: The CACS level of triple vessel disease group was higher than that of double vessel disease group and single vessel disease group, and the CACS level of double vessel disease group was higher than that of single vessel disease group;serum sICAM-1, IL-6, IL-18, CRP, PTX3, Lp-PLA2 and Cat K contents were higher than those of double vessel disease group and single vessel disease group;serum sICAM-1, IL-6, IL-18, CRP, PTX3, Lp-PLA2 and Cat K contents of double vessel disease group were higher than those of single vessel disease group;serum Cys C content of triple vessel disease group was lower than that of double vessel disease group and single vessel disease group, and serum Cys C content of double vessel disease group was lower than that of single vessel disease group. Pearson test showed that the CACS level in patients with coronary heart disease was directly correlated with serum contents of inflammatory factors and plaque stability indexes. Conclusion: The CACS levels in patients with coronary heart disease increase with the aggravation of disease, and the specific CACS level is directly correlated with the degree of inflammatory response and the stability of the plaques.展开更多
In the cooperation model of leading enterprise + farmer,channel stability is always a prominent problem. Based on previous researches,taking farmers in Hainan region as investigation object,the influence factors of ch...In the cooperation model of leading enterprise + farmer,channel stability is always a prominent problem. Based on previous researches,taking farmers in Hainan region as investigation object,the influence factors of channel stability of leading enterprise + farmer are studied by combining the background of formal contract and using the combination method of theory and demonstration. Contract item design,trading cost,product specificity,power structure,information asymmetry and social relationship are contained in analytic framework to establish theoretic model. Research results show that in formal channel management,when contract clause design is more explicit,product specificity is stronger,power structure is more balanced,information share degree is higher,and trading cost is lower,channel is more stable,and farmer's willing to renew contract is stronger. Meanwhile,social relationship plays stronger regulation role.展开更多
The dynamic tree stability assessment technique allows trees to be measured efficiently, under realistic weather conditions. In this study, the stability of four trees, including two conifers and two broad-leaved spec...The dynamic tree stability assessment technique allows trees to be measured efficiently, under realistic weather conditions. In this study, the stability of four trees, including two conifers and two broad-leaved species was assessed in the Botanical Gardens of the University of Sopron, Hungary. The examined trees included Horse chestnut, Japanese zelkova, Douglas fir and Giant sequoia. Each tree was measured in various weather and seasonal conditions. Results show that the seasons affected the stability of broadleaved trees significantly, due to considerable changes in the crown surface area, while this difference was much lower in softwoods. Rainy weather loosens the topsoil, which adversely affects the stability of trees with relatively shallow roots. Lower layers take longer to saturate, and therefore trees with very deep roots are usually unaffected by the looser topsoil, while the increased weight of the top layer compacts the lower layers and improves stability, as evidenced by results measured on Sequoia. Snow accumulation on the branches increases the inertia of the tree, which imposes higher torque on the root collar, decreasing stability. In the meantime, the increased resistance offered by frozen ground stabilizes the tree, which more-or-less counterbalances this effect. A more extensive database of tree stability under different conditions is being built to allow for more comprehensive analysis of various factors, like wind direction, tree health and morphology, shading, etc.展开更多
An unsaturated clay slope, with various sloping angles and a thickness of 14 m, consists of backfill, slope soil and residual soil. Slide interfaces were determined by geophysical approaches and the original slope was...An unsaturated clay slope, with various sloping angles and a thickness of 14 m, consists of backfill, slope soil and residual soil. Slide interfaces were determined by geophysical approaches and the original slope was reconstructed. Sub-slope masses were classified based on the varieties of sloping angle. A force recursive principle was proposed to calculate the stability coefficient of the sub-slope masses. The influencing factors such as sloping angle, water content, hydrostatic pressure, seismic force as well as train load were analyzed. The range and correlation of the above-mentioned factors were discussed and coupled wave equations were established to reflect the relationships between unit weight, cohesion, internal frictional angle, and water content, as well as between internal frictional angle and cohesion. The sensitivity analysis of slope stability was carried out and susceptive factors were determined when the factors were taken as independent and dependent variables respectively. The results show that sloping angle, water content and earthquake are the principal susceptive factors influencing slope stability. The impact of hydrostatic pressure on slope stability is similar to the seismic force in quantity. Train load plays a small role in slope stability and its influencing only reaches the roadbed and its neighboring slope segment. If the factors are taken as independent variables, the influencing extent of water content and cohesion on slope stability can be weakened and train load can be magnified.展开更多
With the growing tension of port shoreline resource in Three Gorges Reservoir area, many wharfs can only be constructed on slippery stratum with poor geological condition, which means buckling failure occurs easily. F...With the growing tension of port shoreline resource in Three Gorges Reservoir area, many wharfs can only be constructed on slippery stratum with poor geological condition, which means buckling failure occurs easily. FEM strength reduction method is used in analyzing slope stability of a wharf in Chongqing, and its accuracy is verified by comparing the acquired results with the computation of traditional limit equilibrium method. On this basis, the influences of reservoir water level variation, overload and backfill material behind the retaining wall, and soil share strength of wharf slope on slippery stratum are analyzed. Analysis shows that, there＇ s a most adverse water level in wharf slope, and the engineering proposals with a certain practical significance such as improve the drainage behind retaining wall, controll overload and improve the strength of backfill soil and subsoil are suggested.展开更多
基金supported by the National Natural Science Foundation of China(Nos.22171102 and 22090044)the National Key R&D Program of China(Nos.2021YFF0500502 and 2023YFA1506304)+2 种基金the Jilin Province Science and Technology Development Plan(No.20230101024JC)the"Medicine+X"crossinnovation team of Bethune Medical Department of Jilin University"Leading the Charge with Open Competition"construction project(No.2022JBGS04)the Jilin University Graduate Training Office(Nos.2021JGZ08 and 2022YJSJIP20).
文摘Solid-state electrolytes(SSEs),as the core component within the next generation of key energy storage technologies-solid-state lithium batteries(SSLBs)-are significantly leading the development of future energy storage systems.Among the numerous types of SSEs,inorganic oxide garnet-structured superionic conductors Li7La3Zr2O12(LLZO)crystallized with the cubic Iaˉ3d space group have received considerable attention owing to their highly advantageous intrinsic properties encompassing reasonable lithium-ion conductivity,wide electrochemical voltage window,high shear modulus,and excellent chemical stability with electrodes.However,no SSEs possess all the properties necessary for SSLBs,thus both the ionic conductivity at room temperature and stability in ambient air regarding cubic garnet-based electrolytes are still subject to further improvement.Hence,this review comprehensively covers the nine key structural factors affecting the ion conductivity of garnet-based electrolytes comprising Li concentration,Li vacancy concentration,Li carrier concentration and mobility,Li occupancy at available sites,lattice constant,triangle bottleneck size,oxygen vacancy defects,and Li-O bonding interactions.Furthermore,the general illustration of structures and fundamental features being crucial to chemical stability is examined,including Li concentration,Li-site occupation behavior,and Li-O bonding interactions.Insights into the composition-structure-property relations among cubic garnet-based oxide ionic conductors from the perspective of their crystal structures,revealing the potential compatibility conflicts between ionic transportation and chemical stability resulting from Li-O bonding interactions.We believe that this review will lay the foundation for future reasonable structural design of oxide-based or even other types of superionic conductors,thus assisting in promoting the rapid development of alternative green and sustainable technologies.
基金Supported by Earmarked Fund for Modern Rapeseed Research System of China(nycytx-00563)High-oil Hybrid Brassica napus Rapeseed Cultivation Technology Research Program of Guizhou Academy of Agricultural Sciences[ZX(2007)015]+3 种基金New High-yield Rapeseed Cultivar Yoyan 599 Cultivation and Promotion Program of Agriculture Department of Guizhou Province[(2009)007]Hybrid Rapeseed Cultivar Youyan 599 Promotion Program of Guizhou Academy of Agricultural Sciences[(2009)030]New High-oil Rapeseed Cultivar Sanbei 98 Cultivation and Promotion Program of Agriculture Department of Guizhou Province[(2010)3087]Earmarked Fund for Modern Rapeseed Research System of Guizhou Province(GZCYTX2013-0802)~~
文摘[Objective] This study aimed to analyze the influence of five cultivation factors： sowing date, plant density, nitrogen fertilizer amount, phosphate fertilizer amount and potash fertilizer amount on oil quality and stability of Brassica napus hybrids. [Method] Statistical analysis was carried out based on the data from previous studies and our work. [Result] Sowing date had no significant influence on oil quality and stability of B. napus hybrids. The plant density shared a positive correlation with 18-C fatty acid （FA） content, unsaturated fatty acid （UFA） content, total content of linoleic acid and linolenic acid, index of unsaturated fatty acid （IUFA）, so a large plant density can improve the oil quality （by increasing18-C FA content, UFA content, total content of linoleic acid and linolenic acid）, but reduce the oil stability （by increasing IUFA）. The amount of nitrogen fertilizer had no significant influence on the contents of 18-C FA and UFA, but significant positive correlations with the total content of linoleic acid and linolenic acid and IUFA. So, the total content of linoleic acid and linolenic acid can be reduced by increasing nitrogen amount, meanwhile the oil stability was also decreased. Phosphate fertilizer amount did not affect 18-C FA significantly, but was negatively correlated with the UFA content, total content of linoleic acid and linolenic acid, and IUFA. So, increasing the amount of applied phosphate fertilizer can reduce UFA content, total content of linoleic acid and linolenic acid, thereby improving oil stability. Potash fertilizer had no significant influence on the IUFA, a significant positive correlation with 18-C FA content, an insignificant positive correlation with the the UFA content, and a negative correlation with the total content of linoleic acid and linolenic acid. The oil content of rapeseed shared an extremely significant positive correlation with 18-C FA content and UFA content, an negative correlation with the total content of linoleic acid and linolenic acid, and no significant correlation with IUFA. [Conclusion] This study identified the effects of five main cultivation factors on oil quality and stability of B. napus hybrids, and the correlations of oil content with 18-C FA content, UFA content, total content of linoleic acid and linolenic acid, and IUFA.
基金supported by Major Program of National Natural Science Foundation of China,No.92368207Frontier Leading Technology BasicResearch Major Project of Jiangsu Province,No.BK20232023(both to XG).
文摘Dorsal root ganglia neurons gradually lose their axonal regeneration ability during development and aging.To explore molecules that enhance axonal regeneration,we screened growth factors with differential gene expression patterns in the dorsal root ganglias of young adult and aged animals following sciatic nerve injury.In young adult animals,two transforming growth factor beta-related factors,activin A and angiopoietin 2,were found to be upregulated post nerve injury.Treatment of isolated dorsal root ganglia explants and cultured dorsal root ganglia neurons of neonatal and young adult rats with recombinant activin A or angiopoietin 2 protein stimulated neurite outgrowth and axonal elongation.The administration of recombinant activin A or angiopoietin 2 protein to sciatic nerve crush-injured dorsal root ganglias also supported the growth of sensory neurons and facilitated nerve regeneration in both young adult and aged rats.Using RNA sequencing,we characterized genetic changes in dorsal root ganglia neurons following recombinant activin A or angiopoietin 2 treatment,revealing the unique mechanisms of these transforming growth factor beta-related factors.Recombinant activin A elicited changes in the gene expression of cytoskeleton-related Gper1 and activated extracellular signal-regulated kinase signaling,while angiopoietin 2 increased the expression of the transcription factor gene E2f2.Our identification of activin A and angiopoietin 2 as crucial promotional factors of axonal regeneration may guide future therapeutic strategies for the treatment of nerve injury.
文摘The paper considers the methodology for a comprehensive analysis of the stability of an open pit-dump system,using limit equilibrium(LEM)and finite element(FEM)methods in the Russian CAE(computer-aided engineering)software Fidesys.It briefly highlights the issues of comparing limit equilibrium methods using the VNIMI(Research Institute of Geomechanics and Mine Surveying-Intersectoral Scientific Center"VNIMI")methodology and a specialized software product with numerical methods.The main focus of this study is to compare the results of the stability analysis in the volumetric model of the open pit-dump system using limit equilibrium and finite element methods in the CAE software Fidesys.It was found that,when modeling the combined operation of an open pit-dump system in complex terrain,both methods should be used,as each has its own advantages.The finite element method,for instance,has certain features that are not present in the calculations using the limit equilibrium approach.As a key scientific contribution,this paper introduces an automation program for calculating the stability of open-pit walls using the limit equilibrium method in CAE Fidesys,which was not previously integrated in the original software.The calculations performed with the use of this newly developed module were compared to those obtained from other widely used software solutions available on the market.The findings demonstrate a remarkable level of convergence in the calculation results for all relevant parameters,including the safety factor,localization,instability type,and deformation.The proposed approach i mproves the accuracy of calculati ons and ensures consistency between the higher stress design zones and the actual deformation and fracture patterns.It also enhances the ability to predict the behavior of rock mass when calculating stability parameters for facilities,both during operation and desi gn.
基金funded by the National Natural Science Foundation of China (Grant No. 51608541)the Postdoctoral Science Foundation of China (Grant No. 2015M580702)the Guizhou Provincial Department of Transportation of China (Grant No. 2014122006)
文摘When the slope is in critical limit equilibrium(LE) state, the strength parameters have different contribution to each other on maintaining slope stability. That is to say that the strength parameters are not simultaneously reduced. Hence, the LE stress method is established to analyze the slope stability by employing the double strengthreduction(DSR) technique in this work. For calculation model of slope stability under the DSR technique, the general nonlinear Mohr–Coulomb(M–C) criterion is used to describe the shear failure of slope. Meanwhile, the average and polar diameter methods via the DSR technique are both adopted to calculate the comprehensive factor of safety(FOS) of slope. To extend the application of the polar diameter method, the original method is improved in the proposed method. After comparison and analysis on some slope examples, the proposed method's feasibility is verified. Thereafter, the stability charts of slope suitable for engineering application are drawn. Moreover, the studies show that:(1) the average method yields similar results as that of the polardiameter method;(2) compared with the traditional uniform strength-reduction(USR) technique, the slope stability obtained using the DSR techniquetends to be more unsafe; and(3) for a slope in the critical LE state, the strength parameter φ, i.e., internal friction angle, has greater contribution on the slope stability than the strength parameters c, i.e., cohesion.
文摘The evaluation of the seismic stability of an expanded municipal solid waste(MSW) landfill is very important in seismic prone zones.In this paper,the pseudo-dynamic method was used to calculate the average safety factor for the expanded landfill with a trapezoidal berm based on under-berm failure conditions.Furthermore,the effects of the variation of parameters such as the amplification factor,seismic coefficient,height of berm,angle of back slope of berm,and depth of waste mass at the back slope on the seismic stability of the landfill were studied.The results indicated that the influences of the vertical seismic coefficient,height of berm,and angle of the back slope of the berm on the seismic stability of the landfill are weakened as the amplification factor increases,but the influence of the horizontal seismic coefficient on the seismic stability of the landfill is strengthened.On the other hand,a certain ratio of the height of the waste mass above the back slope to the depth of waste mass at the back slope,or the reasonable consideration of the magnitude of the amplification factor will be conducive to the seismic design of the landfill.In addition,the results obtained by the pseudo-static and pseudo-dynamic methods were compared.
基金financially supported by the National Natural Science Foundation of China(Grant No.51178402,10902112)Department of Transportation Technology Projects(Grant No.2011318740240)the Fundamental Research Funds for the Central Universities(Grant No.2682014CX074)
文摘Unlike the limit equilibrium method(LEM), with which only the global safety factor of the landslide can be calculated, a local safety factor(LSF) method is proposed to evaluate the stability of different sections of a landslide in this paper. Based on three-dimensional(3D) numerical simulation results, the local safety factor is defined as the ratio of the shear strength of the soil at an element on the slip zone to the shear stress parallel to the sliding direction at that element. The global safety factor of the landslide is defined as the weighted average of all local safety factors based on the area of the slip surface. Some example analyses show that the results computed by the LSF method agree well with those calculated by the General Limit Equilibrium(GLE) method in two-dimensional(2D) models and the distribution of the LSF in the 3D slip zone is consistent with that indicated by the observed deformation pattern of an actual landslide in China.
基金provided by the National Natural Science Foundation of China (Nos. 51504259 and 51234005)the Fundamental Research Funds for the Central Universities (No. 2010QZ06)
文摘Deep beam anchorage structures based on spatial distribution analysis of the cable prestressed field have been proposed for roadway roof support, Stability and other factors that influence deep beam structures are studied in this paper using mechanical calculations, numerical analysis and field measurements, A mechanical model of deep beam structure subjected to multiple loading is established, including analysis of roof support in the return airway of S1203 working face in the Yuwu coal mine, China, The expression of maximum shear stress in the deep beam structure is deduced according to the stress superposition criterion, It is found that the primary factors affecting deep beam structure stability are deep beam thickness, cable pre-tension and cable spacing, The variation of maximum shear stress distribution and prestressed field diffusion effects according to various factors are analyzed using Matlah and FLAC3DTM software, and practical support parameters of the S1203 return airway roof are determined, According to the observations of rock pressure, there is no evidence of roof separation, and the maximum values of roof subsidence and convergence of wall rock are 72 and 48 mm, respectively, The results show that the proposed roof support design with a deep beam structure is feasible and achieves effective control of the roadway roof,
基金support in providing the data and the Universiti Teknologi Malaysia supported this work under UTM Flagship CoE/RG-Coe/RG 5.2:Evaluating Surface PGA with Global Ground Motion Site Response Analyses for the highest seismic activity location in Peninsular Malaysia(Q.J130000.5022.10G47)Universiti Teknologi Malaysia-Earthquake Hazard Assessment in Peninsular Malaysia Using Probabilistic Seismic Hazard Analysis(PSHA)Method(Q.J130000.21A2.06E9).
文摘The prediction of slope stability is a complex nonlinear problem.This paper proposes a new method based on the random forest(RF)algorithm to study the rocky slopes stability.Taking the Bukit Merah,Perak and Twin Peak(Kuala Lumpur)as the study area,the slope characteristics of geometrical parameters are obtained from a multidisciplinary approach(consisting of geological,geotechnical,and remote sensing analyses).18 factors,including rock strength,rock quality designation(RQD),joint spacing,continuity,openness,roughness,filling,weathering,water seepage,temperature,vegetation index,water index,and orientation,are selected to construct model input variables while the factor of safety(FOS)functions as an output.The area under the curve(AUC)value of the receiver operating characteristic(ROC)curve is obtained with precision and accuracy and used to analyse the predictive model ability.With a large training set and predicted parameters,an area under the ROC curve(the AUC)of 0.95 is achieved.A precision score of 0.88 is obtained,indicating that the model has a low false positive rate and correctly identifies a substantial number of true positives.The findings emphasise the importance of using a variety of terrain characteristics and different approaches to characterise the rock slope.
基金Supported by the National Natural Science Foundation Project (71173035)the National Soft Science Research Plan (2010GXQ5D330)the Plan for Key Teachers of Heilongjiang Province (GC10D206)
文摘To make grain price stable is an important goal for the Chinese government. The paper compared the grain supply elasticity and demand elasticity to determine the grain price stability in China; used ＂k value＂ method to analyze the grain price fluctuation from 1985 to 2010; divided the grain price volatility into three stages; and analyzed the factors in each phase. On the base, it put forward some countermeasures to guarantee the stability of the grain price.
基金National Natural Science Foundation of China (No.51278182)
文摘When the bridge structure stability safety factor of the first type is 4, the research that whether the structure reliability index will reach target reliability index under the more-likely-to-happen collapse situation of the second type is necessary. The stability calculations of the first and the second type are made respectively for single layer and single span rigid frame bridge. Based on the critical load obtained from the stability calculation of the first type, the stability safety factor of the first type is taken as 4, and the first order reliability method is used to program and calculate the reliability index. Then, the load effect under the stability reliability index cal- culation of the first type and the critical load of the second type are employed to calculate the reliability index of the second type. The evaluation of structure stability safety factor is discussed according to reliability index. Based on the discussion above, parameter analysis of the stable critical loads of two types is made, and the in- fluence of critical load change on reliability index is researched. The result shows that stability analysis should identify collapse state; when the stability safety factor of the first type is 4, but the structure has the collapse of the second type, the reliability index cannot be ensured to reach the target reliability index under certain condi- tions.
文摘Here,we provide data suggesting that the absence of silencing of the ectopic reprogramming factors used to reprogram somatic cells to induced pluripotent stem cells(iPSCs)may predispose iPSCs to genomic instability.We encourage stem cell scientists to undertake an extensive characterization and standardization of much larger cohorts of iPSC lines in order to set up rigorous criteria to define safe and stable bonafide iPSCs.
基金Financial support for this work, provided by the National Natural Science Foundation of China (No.51404013)the Natural Science Foundation of Anhui Province (Nos.1508085ME77 and 1508085QE89)the Open Projects of State Key Laboratory for Geomechanics & Deep Underground Engineering at the China University of Mining and Technology (No.SKLGDUEK1212)
文摘The effect of controlling strata movement in solid filling mining depends on the filling rate of the goal. However, the mechanical property of the overburden in the backfill stope and the designed size of the backfill mining workface should also be considered. In this study, we established a main roof strata model with loads in accordance with the theory of key strata to investigate the stability of the overburden in solid dense filling mining. We analyzed the stress distribution law of the main roof strata based on elastic thin plate theory. The results show that the position of the long side midpoint of the main roof strata failed more easily because of tensile yield, indicating that this position is the area where failure is likely to occur more easily. We also deduced the stability mechanics criterion of the main roof strata based on tensile yield criterion. The factors affecting the stability of the overburden in solid dense filling mining were also analyzed, including the thickness and elasticity modulus of the main roof strata, overlying strata loads, advanced distance and length of workface, and elastic foundation coefficient of backfill body. The research achievements can provide an important theoretical basis for determining the designed size of the solid dense filling mining workface.
文摘The southern forest ecosystem of Cameroon extends from latitude 2° to 6°N and from 10° to 16°E. In order to investigate about the influence of climate factors on the infrastructures, the main parameters of local climate of that ecosystem have been evaluated. The results show that, the factors are stable and have a common trend. But, the abundance of precipitations;the important hydrographic network and the presence of dense forest appear as the majors climatic constraints that may be taken in account to ensure the stability of the infrastructures in forest ecosystem.
文摘Light is an environmental signaling,whereas Aux/IAA proteins and Auxin Response Factors(ARFs)are regulators of auxin signalling.Aux/IAA proteins are unstable,and their degradation dependents on 26S ubiquitin-proteasome and is promoted by Auxin.Auxin binds directly to a SCF-type ubiquitin-protein ligase,TIR1,facilitates the interaction between Aux/IAA proteins and TIR1,and then the degradation of Aux/IAA proteins.A few studies have reported that some ARFs are also unstable proteins,and their degradation is also mediated by 26S proteasome.In this study,by using of antibodies recognizing endogenous ARF7 proteins,we found that protein stability of ARF7 was affected by light.By expressing MYC tagged ARF activators in protoplasts,we found that degradation of ARF7 was inhibited by 26 proteasome inhibitors.In addition,at least ARF5 and ARF19 were also unstable proteins,and degradation of ARF5 via 26S proteasome was further confirmed by using stable transformed plants overexpressing ARF5 with a GUS tag.
文摘Objective: To investigate the correlation of coronary CTA calcification score (CACS) with serum inflammatory factors and plaque stability-related indexes in patients with coronary heart disease. Methods: A total of 228 patients with possible coronary heart disease who were examined in this hospital between November 2014 and March 2017 were selected, and the CACS levels as well as the serum contents of inflammatory factors and plaque stability indexes in patients with different lesions were determined. Pearson test was used to assess the correlation between CACS level and disease severity in patients with coronary heart disease. Results: The CACS level of triple vessel disease group was higher than that of double vessel disease group and single vessel disease group, and the CACS level of double vessel disease group was higher than that of single vessel disease group;serum sICAM-1, IL-6, IL-18, CRP, PTX3, Lp-PLA2 and Cat K contents were higher than those of double vessel disease group and single vessel disease group;serum sICAM-1, IL-6, IL-18, CRP, PTX3, Lp-PLA2 and Cat K contents of double vessel disease group were higher than those of single vessel disease group;serum Cys C content of triple vessel disease group was lower than that of double vessel disease group and single vessel disease group, and serum Cys C content of double vessel disease group was lower than that of single vessel disease group. Pearson test showed that the CACS level in patients with coronary heart disease was directly correlated with serum contents of inflammatory factors and plaque stability indexes. Conclusion: The CACS levels in patients with coronary heart disease increase with the aggravation of disease, and the specific CACS level is directly correlated with the degree of inflammatory response and the stability of the plaques.
基金Supported by National Natural Science Foundation Item(71573100)
文摘In the cooperation model of leading enterprise + farmer,channel stability is always a prominent problem. Based on previous researches,taking farmers in Hainan region as investigation object,the influence factors of channel stability of leading enterprise + farmer are studied by combining the background of formal contract and using the combination method of theory and demonstration. Contract item design,trading cost,product specificity,power structure,information asymmetry and social relationship are contained in analytic framework to establish theoretic model. Research results show that in formal channel management,when contract clause design is more explicit,product specificity is stronger,power structure is more balanced,information share degree is higher,and trading cost is lower,channel is more stable,and farmer's willing to renew contract is stronger. Meanwhile,social relationship plays stronger regulation role.
文摘The dynamic tree stability assessment technique allows trees to be measured efficiently, under realistic weather conditions. In this study, the stability of four trees, including two conifers and two broad-leaved species was assessed in the Botanical Gardens of the University of Sopron, Hungary. The examined trees included Horse chestnut, Japanese zelkova, Douglas fir and Giant sequoia. Each tree was measured in various weather and seasonal conditions. Results show that the seasons affected the stability of broadleaved trees significantly, due to considerable changes in the crown surface area, while this difference was much lower in softwoods. Rainy weather loosens the topsoil, which adversely affects the stability of trees with relatively shallow roots. Lower layers take longer to saturate, and therefore trees with very deep roots are usually unaffected by the looser topsoil, while the increased weight of the top layer compacts the lower layers and improves stability, as evidenced by results measured on Sequoia. Snow accumulation on the branches increases the inertia of the tree, which imposes higher torque on the root collar, decreasing stability. In the meantime, the increased resistance offered by frozen ground stabilizes the tree, which more-or-less counterbalances this effect. A more extensive database of tree stability under different conditions is being built to allow for more comprehensive analysis of various factors, like wind direction, tree health and morphology, shading, etc.
基金This work was financially supported by the National Natural Science Foundation of China (No. 50490271).
文摘An unsaturated clay slope, with various sloping angles and a thickness of 14 m, consists of backfill, slope soil and residual soil. Slide interfaces were determined by geophysical approaches and the original slope was reconstructed. Sub-slope masses were classified based on the varieties of sloping angle. A force recursive principle was proposed to calculate the stability coefficient of the sub-slope masses. The influencing factors such as sloping angle, water content, hydrostatic pressure, seismic force as well as train load were analyzed. The range and correlation of the above-mentioned factors were discussed and coupled wave equations were established to reflect the relationships between unit weight, cohesion, internal frictional angle, and water content, as well as between internal frictional angle and cohesion. The sensitivity analysis of slope stability was carried out and susceptive factors were determined when the factors were taken as independent and dependent variables respectively. The results show that sloping angle, water content and earthquake are the principal susceptive factors influencing slope stability. The impact of hydrostatic pressure on slope stability is similar to the seismic force in quantity. Train load plays a small role in slope stability and its influencing only reaches the roadbed and its neighboring slope segment. If the factors are taken as independent variables, the influencing extent of water content and cohesion on slope stability can be weakened and train load can be magnified.
文摘With the growing tension of port shoreline resource in Three Gorges Reservoir area, many wharfs can only be constructed on slippery stratum with poor geological condition, which means buckling failure occurs easily. FEM strength reduction method is used in analyzing slope stability of a wharf in Chongqing, and its accuracy is verified by comparing the acquired results with the computation of traditional limit equilibrium method. On this basis, the influences of reservoir water level variation, overload and backfill material behind the retaining wall, and soil share strength of wharf slope on slippery stratum are analyzed. Analysis shows that, there＇ s a most adverse water level in wharf slope, and the engineering proposals with a certain practical significance such as improve the drainage behind retaining wall, controll overload and improve the strength of backfill soil and subsoil are suggested.
