A dual-phase synergistic enhancement method was adopted to strengthen the Al-Mn-Mg-Sc-Zr alloy fabricated by laser powder bed fusion(LPBF)by leveraging the unique advantages of Er and TiB_(2).Spherical powders of 0.5w...A dual-phase synergistic enhancement method was adopted to strengthen the Al-Mn-Mg-Sc-Zr alloy fabricated by laser powder bed fusion(LPBF)by leveraging the unique advantages of Er and TiB_(2).Spherical powders of 0.5wt%Er-1wt%TiB_(2)/Al-Mn-Mg-Sc-Zr nanocomposite were prepared using vacuum homogenization technique,and the density of samples prepared through the LPBF process reached 99.8%.The strengthening and toughening mechanisms of Er-TiB_(2)were investigated.The results show that Al_(3)Er diffraction peaks are detected by X-ray diffraction analysis,and texture strength decreases according to electron backscatter diffraction results.The added Er and TiB_(2)nano-reinforcing phases act as heterogeneous nucleation sites during the LPBF forming process,hindering grain growth and effectively refining the grains.After incorporating the Er-TiB_(2)dual-phase nano-reinforcing phases,the tensile strength and elongation at break of the LPBF-deposited samples reach 550 MPa and 18.7%,which are 13.4%and 26.4%higher than those of the matrix material,respectively.展开更多
BACKGROUND Lumbar interbody fusion(LIF)is the primary treatment for lumbar degenerative diseases.Elderly patients are prone to anxiety and depression after undergoing surgery,which affects their postoperative recovery...BACKGROUND Lumbar interbody fusion(LIF)is the primary treatment for lumbar degenerative diseases.Elderly patients are prone to anxiety and depression after undergoing surgery,which affects their postoperative recovery speed and quality of life.Effective prevention of anxiety and depression in elderly patients has become an urgent problem.AIM To investigate the trajectory of anxiety and depression levels in elderly patients after LIF,and the influencing factors.METHODS Random sampling was used to select 239 elderly patients who underwent LIF from January 2020 to December 2024 in Shenzhen Pingle Orthopedic Hospital.General information and surgery-related indices were recorded,and participants completed measures of psychological status,lumbar spine dysfunction,and quality of life.A latent class growth model was used to analyze the post-LIF trajectory of anxiety and depression levels,and unordered multi-categorical logistic regression was used to analyze the influencing factors.RESULTS Three trajectories of change in anxiety level were identified:Increasing anxiety(n=26,10.88%),decreasing anxiety(n=27,11.30%),and stable anxiety(n=186,77.82%).Likewise,three trajectories of change in depression level were identified:Increasing depression(n=30,12.55%),decreasing depression(n=26,10.88%),and stable depression(n=183,76.57%).Regression analysis showed that having no partner,female sex,elevated Oswestry dysfunction index(ODI)scores,and reduced 36-Item Short Form Health Survey scores all contributed to increased anxiety levels,whereas female sex,postoperative opioid use,and elevated ODI scores all contributed to increased depression levels.CONCLUSION During clinical observation,combining factors to predict anxiety and depression in post-LIF elderly patients enables timely intervention,quickens recovery,and enhances quality of life.展开更多
BACKGROUND Salvage of the infected long stem revision total knee arthroplasty is challenging due to the presence of well-fixed ingrown or cemented stems.Reconstructive options are limited.Above knee amputation(AKA)is ...BACKGROUND Salvage of the infected long stem revision total knee arthroplasty is challenging due to the presence of well-fixed ingrown or cemented stems.Reconstructive options are limited.Above knee amputation(AKA)is often recommended.We present a surgical technique that was successfully used on four such patients to convert them to a knee fusion(KF)using a cephalomedullary nail.CASE SUMMARY Four patients with infected long stem revision knee replacements that refused AKA had a single stage removal of their infected revision total knee followed by a KF.They were all treated with a statically locked antegrade cephalomedullary fusion nail,augmented with antibiotic impregnated bone cement.All patients had successful limb salvage and were ambulatory with assistive devices at the time of last follow-up.All were infection free at an average follow-up of 25.5 months(range 16-31).CONCLUSION Single stage cephalomedullary nailing can result in a successful KF in patients with infected long stem revision total knees.展开更多
Driving of the nuclear fusion reaction p+^(11)B3α+8.7 MeV under laboratory conditions by interaction between high-power laser pulses and matter has become a popular field of research,owing to its numerous potential a...Driving of the nuclear fusion reaction p+^(11)B3α+8.7 MeV under laboratory conditions by interaction between high-power laser pulses and matter has become a popular field of research,owing to its numerous potential applications:as an alternative to deuterium-tritium for fusion energy production,astrophysics studies,and alpha-particle generation for medical treatment.One possible scheme for laser-driven p-^(11)B reactions is to direct a beam of laser-accelerated protons onto a boron(B)sample(the so-called“pitcher-catcher”scheme).This technique has been successfully implemented on large high-energy lasers,yielding hundreds of joules per shot at low repetition.We present here a complementary approach,exploiting the high repetition rate of the VEGA III petawatt laser at CLPU(Spain),aiming at accumulating results from many interactions at much lower energy,to provide better control of the parameters and the statistics of the measurements.Despite a moderate energy per pulse,our experiment allowed exploration of the laser-driven fusion process with tens(up to hundreds)of laser shots.The experiment provided a clear signature of the reactions involved and of the fusion products,accumulated over many shots,leading to an improved optimization of the diagnostics for experimental campaigns of this type.In this paper,we discuss the effectiveness of laser-driven p-11B fusion in the pitcher-catcher scheme,at a high repetition rate,addressing the challenges of this experimental scheme and highlighting its critical aspects.Our proposed methodology allows evaluation of the performance of this scheme for laser-driven alpha particle production and can be adapted to high-repetition-rate laser facilities with higher energy and intensity.展开更多
An improved model based on you only look once version 8(YOLOv8)is proposed to solve the problem of low detection accuracy due to the diversity of object sizes in optical remote sensing images.Firstly,the feature pyram...An improved model based on you only look once version 8(YOLOv8)is proposed to solve the problem of low detection accuracy due to the diversity of object sizes in optical remote sensing images.Firstly,the feature pyramid network(FPN)structure of the original YOLOv8 mode is replaced by the generalized-FPN(GFPN)structure in GiraffeDet to realize the"cross-layer"and"cross-scale"adaptive feature fusion,to enrich the semantic information and spatial information on the feature map to improve the target detection ability of the model.Secondly,a pyramid-pool module of multi atrous spatial pyramid pooling(MASPP)is designed by using the idea of atrous convolution and feature pyramid structure to extract multi-scale features,so as to improve the processing ability of the model for multi-scale objects.The experimental results show that the detection accuracy of the improved YOLOv8 model on DIOR dataset is 92%and mean average precision(mAP)is 87.9%,respectively 3.5%and 1.7%higher than those of the original model.It is proved the detection and classification ability of the proposed model on multi-dimensional optical remote sensing target has been improved.展开更多
To address the challenge of missing modal information in entity alignment and to mitigate information loss or bias arising frommodal heterogeneity during fusion,while also capturing shared information acrossmodalities...To address the challenge of missing modal information in entity alignment and to mitigate information loss or bias arising frommodal heterogeneity during fusion,while also capturing shared information acrossmodalities,this paper proposes a Multi-modal Pre-synergistic Entity Alignmentmodel based on Cross-modalMutual Information Strategy Optimization(MPSEA).The model first employs independent encoders to process multi-modal features,including text,images,and numerical values.Next,a multi-modal pre-synergistic fusion mechanism integrates graph structural and visual modal features into the textual modality as preparatory information.This pre-fusion strategy enables unified perception of heterogeneous modalities at the model’s initial stage,reducing discrepancies during the fusion process.Finally,using cross-modal deep perception reinforcement learning,the model achieves adaptive multilevel feature fusion between modalities,supporting learningmore effective alignment strategies.Extensive experiments on multiple public datasets show that the MPSEA method achieves gains of up to 7% in Hits@1 and 8.2% in MRR on the FBDB15K dataset,and up to 9.1% in Hits@1 and 7.7% in MRR on the FBYG15K dataset,compared to existing state-of-the-art methods.These results confirm the effectiveness of the proposed model.展开更多
Fourier ptychographic microscopy(FPM)is an innovative computational microscopy approach that enables high-throughput imaging with high resolution,wide field of view,and quantitative phase imaging(QPI)by simultaneously...Fourier ptychographic microscopy(FPM)is an innovative computational microscopy approach that enables high-throughput imaging with high resolution,wide field of view,and quantitative phase imaging(QPI)by simultaneously capturing bright-field and dark-field images.However,effectively utilizing dark-field intensity images,including both normally exposed and overexposed data,which contain valuable high-angle illumination information,remains a complex challenge.Successfully extracting and applying this information could significantly enhance phase reconstruction,benefiting processes such as virtual staining and QPI imaging.To address this,we introduce a multi-exposure image fusion(MEIF)framework that optimizes dark-field information by incorporating it into the FPM preprocessing workflow.MEIF increases the data available for reconstruction without requiring changes to the optical setup.We evaluate the framework using both feature-domain and traditional FPM,demonstrating that it achieves substantial improvements in intensity resolution and phase information for biological samples that exceed the performance of conventional high dynamic range(HDR)methods.This image preprocessing-based information-maximization strategy fully leverages existing datasets and offers promising potential to drive advancements in fields such as microscopy,remote sensing,and crystallography.展开更多
Feature fusion is an important technique in medical image classification that can improve diagnostic accuracy by integrating complementary information from multiple sources.Recently,Deep Learning(DL)has been widely us...Feature fusion is an important technique in medical image classification that can improve diagnostic accuracy by integrating complementary information from multiple sources.Recently,Deep Learning(DL)has been widely used in pulmonary disease diagnosis,such as pneumonia and tuberculosis.However,traditional feature fusion methods often suffer from feature disparity,information loss,redundancy,and increased complexity,hindering the further extension of DL algorithms.To solve this problem,we propose a Graph-Convolution Fusion Network with Self-Supervised Feature Alignment(Self-FAGCFN)to address the limitations of traditional feature fusion methods in deep learning-based medical image classification for respiratory diseases such as pneumonia and tuberculosis.The network integrates Convolutional Neural Networks(CNNs)for robust feature extraction from two-dimensional grid structures and Graph Convolutional Networks(GCNs)within a Graph Neural Network branch to capture features based on graph structure,focusing on significant node representations.Additionally,an Attention-Embedding Ensemble Block is included to capture critical features from GCN outputs.To ensure effective feature alignment between pre-and post-fusion stages,we introduce a feature alignment loss that minimizes disparities.Moreover,to address the limitations of proposed methods,such as inappropriate centroid discrepancies during feature alignment and class imbalance in the dataset,we develop a Feature-Centroid Fusion(FCF)strategy and a Multi-Level Feature-Centroid Update(MLFCU)algorithm,respectively.Extensive experiments on public datasets LungVision and Chest-Xray demonstrate that the Self-FAGCFN model significantly outperforms existing methods in diagnosing pneumonia and tuberculosis,highlighting its potential for practical medical applications.展开更多
A novel dual-branch decoding fusion convolutional neural network model(DDFNet)specifically designed for real-time salient object detection(SOD)on steel surfaces is proposed.DDFNet is based on a standard encoder–decod...A novel dual-branch decoding fusion convolutional neural network model(DDFNet)specifically designed for real-time salient object detection(SOD)on steel surfaces is proposed.DDFNet is based on a standard encoder–decoder architecture.DDFNet integrates three key innovations:first,we introduce a novel,lightweight multi-scale progressive aggregation residual network that effectively suppresses background interference and refines defect details,enabling efficient salient feature extraction.Then,we propose an innovative dual-branch decoding fusion structure,comprising the refined defect representation branch and the enhanced defect representation branch,which enhance accuracy in defect region identification and feature representation.Additionally,to further improve the detection of small and complex defects,we incorporate a multi-scale attention fusion module.Experimental results on the public ESDIs-SOD dataset show that DDFNet,with only 3.69 million parameters,achieves detection performance comparable to current state-of-the-art models,demonstrating its potential for real-time industrial applications.Furthermore,our DDFNet-L variant consistently outperforms leading methods in detection performance.The code is available at https://github.com/13140W/DDFNet.展开更多
Visible-infrared object detection leverages the day-night stable object perception capability of infrared images to enhance detection robustness in low-light environments by fusing the complementary information of vis...Visible-infrared object detection leverages the day-night stable object perception capability of infrared images to enhance detection robustness in low-light environments by fusing the complementary information of visible and infrared images.However,the inherent differences in the imaging mechanisms of visible and infrared modalities make effective cross-modal fusion challenging.Furthermore,constrained by the physical characteristics of sensors and thermal diffusion effects,infrared images generally suffer from blurred object contours and missing details,making it difficult to extract object features effectively.To address these issues,we propose an infrared-visible image fusion network that realizesmultimodal information fusion of infrared and visible images through a carefully designedmultiscale fusion strategy.First,we design an adaptive gray-radiance enhancement(AGRE)module to strengthen the detail representation in infrared images,improving their usability in complex lighting scenarios.Next,we introduce a channelspatial feature interaction(CSFI)module,which achieves efficient complementarity between the RGB and infrared(IR)modalities via dynamic channel switching and a spatial attention mechanism.Finally,we propose a multi-scale enhanced cross-attention fusion(MSECA)module,which optimizes the fusion ofmulti-level features through dynamic convolution and gating mechanisms and captures long-range complementary relationships of cross-modal features on a global scale,thereby enhancing the expressiveness of the fused features.Experiments on the KAIST,M3FD,and FLIR datasets demonstrate that our method delivers outstanding performance in daytime and nighttime scenarios.On the KAIST dataset,the miss rate drops to 5.99%,and further to 4.26% in night scenes.On the FLIR and M3FD datasets,it achieves AP50 scores of 79.4% and 88.9%,respectively.展开更多
This paper presents an enhanced version of the correlation-driven dual-branch feature decomposition framework(CDDFuse)for fusing low-and high-exposure images captured by the G400BSI sensor.We introduce a novel neural ...This paper presents an enhanced version of the correlation-driven dual-branch feature decomposition framework(CDDFuse)for fusing low-and high-exposure images captured by the G400BSI sensor.We introduce a novel neural long-term memory(NLM)module into the CDDFuse architecture to improve feature extraction by leveraging persistent global feature representations across image sequences.The proposed method effectively preserves dynamic range and structural details,and is evaluated using a new metric,the ATEF dynamic range preservation index(ATEF-DRPI).Experimental results on a G400BSI dataset demonstrate superior fusion quality,with ATEF-DRPI scores of 0.90,a 12.5%improvement over that of the baseline CDDFuse(0.80),indicating better detail retention in bright and dark regions.This work advances image fusion techniques for extreme lighting conditions,offering improved performance for downstream vision tasks.展开更多
The effect of drive laser wavelength on the growth of ablative Rayleigh–Taylor instability(ARTI)in inertial confinemen fusion(ICF)is studied with two-dimensional numerical simulations.The results show that in the pla...The effect of drive laser wavelength on the growth of ablative Rayleigh–Taylor instability(ARTI)in inertial confinemen fusion(ICF)is studied with two-dimensional numerical simulations.The results show that in the plasma acceleration phase,shorter wavelengths lead to more efficien coupling between the laser and the kinetic energy of the implosion fluid Under the condition that the laser energy coupled to the implosion flui is constant,the ARTI growth rate decreases as the laser wavelength moves toward the extreme ultraviolet band,reaching its minimum value near λ=65 nm,and when the laser wavelength continuously moves toward the X-ray band,the ARTI growth rate increases rapidly.It is found that the results deviate from the theoretical ARTI growth rate.As the laser intensity benchmark increases,the position of the minimum ARTI growth rate shifts toward shorter wavelengths.As the initial sinusoidal perturbation wavenumber decreases,the position of the minimum ARTI growth rate shifts toward longer wavelengths.We believe that the conclusions drawn from the present simulations and analysis will help provide a better understanding of the ICF process and improve the theory of ARTI growth.展开更多
Hydrodynamic instability growth at the deuterium-tritium(DT)fuel-ablator interface plays a critical role in determining the performance of inertial confinement fusion implosions.During the late stages of implosion,ins...Hydrodynamic instability growth at the deuterium-tritium(DT)fuel-ablator interface plays a critical role in determining the performance of inertial confinement fusion implosions.During the late stages of implosion,insufficient doping of the ablator material can result in highenergy X-ray preheat,which may trigger the development of a classical-like Rayleigh-Taylor instability(RTI)at the fuel-ablator interface.In implosion experiments at the Shenguang 100 kJ-level laser facility,the primary source of perturbation is the roughness of the inner DT ice interface.In this study,we propose an analytical model to describe the feed-out process of the initial roughness of the inner DT ice interface.The perturbation amplitude derived from this model serves as the initial seed for the late-time RTI during the acceleration phase.Our findings confirm the presence of classical-like RTI at the fuel-ablator interface.Numerical simulations conducted using a radiation hydrodynamic code validate the proposed analytical model and demonstrate the existence of a peak mode number in both the feed-out process and the classical-like RTI.It provides an alternative bridge between the current target fabrication limitations and the unexpected implosion performance.展开更多
Infrared and visible image fusion technology integrates the thermal radiation information of infrared images with the texture details of visible images to generate more informative fused images.However,existing method...Infrared and visible image fusion technology integrates the thermal radiation information of infrared images with the texture details of visible images to generate more informative fused images.However,existing methods often fail to distinguish salient objects from background regions,leading to detail suppression in salient regions due to global fusion strategies.This study presents a mask-guided latent low-rank representation fusion method to address this issue.First,the GrabCut algorithm is employed to extract a saliency mask,distinguishing salient regions from background regions.Then,latent low-rank representation(LatLRR)is applied to extract deep image features,enhancing key information extraction.In the fusion stage,a weighted fusion strategy strengthens infrared thermal information and visible texture details in salient regions,while an average fusion strategy improves background smoothness and stability.Experimental results on the TNO dataset demonstrate that the proposed method achieves superior performance in SPI,MI,Qabf,PSNR,and EN metrics,effectively preserving salient target details while maintaining balanced background information.Compared to state-of-the-art fusion methods,our approach achieves more stable and visually consistent fusion results.The fusion code is available on GitHub at:https://github.com/joyzhen1/Image(accessed on 15 January 2025).展开更多
In this review paper on heavy ion inertial fusion(HIF),the state-of-the-art scientific results are presented and discussed on the HIF physics,including physics of the heavy ion beam(HIB)transport in a fusion reactor,t...In this review paper on heavy ion inertial fusion(HIF),the state-of-the-art scientific results are presented and discussed on the HIF physics,including physics of the heavy ion beam(HIB)transport in a fusion reactor,the HIBs-ion illumination on a direct-drive fuel target,the fuel target physics,the uniformity of the HIF target implosion,the smoothing mechanisms of the target implosion non-uniformity and the robust target implosion.The HIB has remarkable preferable features to release the fusion energy in inertial fusion:in particle accelerators HIBs are generated with a high driver efficiency of~30%-40%,and the HIB ions deposit their energy inside of materials.Therefore,a requirement for the fusion target energy gain is relatively low,that would be~50-70 to operate a HIF fusion reactor with the standard energy output of 1 GWof electricity.The HIF reactor operation frequency would be~10-15 Hz or so.Several-MJ HIBs illuminate a fusion fuel target,and the fuel target is imploded to about a thousand times of the solid density.Then the DT fuel is ignited and burned.The HIB ion deposition range is defined by the HIB ions stopping length,which would be~1 mm or so depending on the material.Therefore,a relatively large density-scale length appears in the fuel target material.One of the critical issues in inertial fusion would be a spherically uniform target compression,which would be degraded by a non-uniform implosion.The implosion non-uniformity would be introduced by the Rayleigh-Taylor(R-T)instability,and the large densitygradient-scale length helps to reduce the R-T growth rate.On the other hand,the large scale length of the HIB ions stopping range suggests that the temperature at the energy deposition layer in a HIF target does not reach a very-high temperature:normally about 300 eV or so is realized in the energy absorption region,and that a direct-drive target would be appropriate in HIF.In addition,the HIB accelerators are operated repetitively and stably.The precise control of the HIB axis manipulation is also realized in the HIF accelerator,and the HIB wobbling motion may give another tool to smooth the HIB illumination non-uniformity.The key issues in HIF physics are also discussed and presented in the paper.展开更多
Signal transducer and activator of transcription（STAT）is a unique protein family that binds to DNA,coupled with tyrosine phosphorylation signaling pathways,acting as a transcriptional regulator to mediate a variety ...Signal transducer and activator of transcription（STAT）is a unique protein family that binds to DNA,coupled with tyrosine phosphorylation signaling pathways,acting as a transcriptional regulator to mediate a variety of biological effects.Cerebral ischemia and reperfusion can activate STATs signaling pathway,but no studies have confirmed whether STAT activation can be verified by diffusion-weighted magnetic resonance imaging（DWI）in rats after cerebral ischemia/reperfusion.Here,we established a rat model of focal cerebral ischemia injury using the modified Longa method.DWI revealed hyperintensity in parts of the left hemisphere before reperfusion and a low apparent diffusion coefficient.STAT3 protein expression showed no significant change after reperfusion,but phosphorylated STAT3 expression began to increase after 30 minutes of reperfusion and peaked at 24 hours.Pearson correlation analysis showed that STAT3 activation was correlated positively with the relative apparent diffusion coefficient and negatively with the DWI abnormal signal area.These results indicate that DWI is a reliable representation of the infarct area and reflects STAT phosphorylation in rat brain following focal cerebral ischemia/reperfusion.展开更多
基金Shaanxi Province Qin Chuangyuan“Scientist+Engineer”Team Construction Project(2022KXJ-071)2022 Qin Chuangyuan Achievement Transformation Incubation Capacity Improvement Project(2022JH-ZHFHTS-0012)+8 种基金Shaanxi Province Key Research and Development Plan-“Two Chains”Integration Key Project-Qin Chuangyuan General Window Industrial Cluster Project(2023QCY-LL-02)Xixian New Area Science and Technology Plan(2022-YXYJ-003,2022-XXCY-010)2024 Scientific Research Project of Shaanxi National Defense Industry Vocational and Technical College(Gfy24-07)Shaanxi Vocational and Technical Education Association 2024 Vocational Education Teaching Reform Research Topic(2024SZX354)National Natural Science Foundation of China(U24A20115)2024 Shaanxi Provincial Education Department Service Local Special Scientific Research Program Project-Industrialization Cultivation Project(24JC005,24JC063)Shaanxi Province“14th Five-Year Plan”Education Science Plan,2024 Project(SGH24Y3181)National Key Research and Development Program of China(2023YFB4606400)Longmen Laboratory Frontier Exploration Topics Project(LMQYTSKT003)。
文摘A dual-phase synergistic enhancement method was adopted to strengthen the Al-Mn-Mg-Sc-Zr alloy fabricated by laser powder bed fusion(LPBF)by leveraging the unique advantages of Er and TiB_(2).Spherical powders of 0.5wt%Er-1wt%TiB_(2)/Al-Mn-Mg-Sc-Zr nanocomposite were prepared using vacuum homogenization technique,and the density of samples prepared through the LPBF process reached 99.8%.The strengthening and toughening mechanisms of Er-TiB_(2)were investigated.The results show that Al_(3)Er diffraction peaks are detected by X-ray diffraction analysis,and texture strength decreases according to electron backscatter diffraction results.The added Er and TiB_(2)nano-reinforcing phases act as heterogeneous nucleation sites during the LPBF forming process,hindering grain growth and effectively refining the grains.After incorporating the Er-TiB_(2)dual-phase nano-reinforcing phases,the tensile strength and elongation at break of the LPBF-deposited samples reach 550 MPa and 18.7%,which are 13.4%and 26.4%higher than those of the matrix material,respectively.
基金Supported by the Scientific Research Projects of the Health System in Pingshan District,No.2023122.
文摘BACKGROUND Lumbar interbody fusion(LIF)is the primary treatment for lumbar degenerative diseases.Elderly patients are prone to anxiety and depression after undergoing surgery,which affects their postoperative recovery speed and quality of life.Effective prevention of anxiety and depression in elderly patients has become an urgent problem.AIM To investigate the trajectory of anxiety and depression levels in elderly patients after LIF,and the influencing factors.METHODS Random sampling was used to select 239 elderly patients who underwent LIF from January 2020 to December 2024 in Shenzhen Pingle Orthopedic Hospital.General information and surgery-related indices were recorded,and participants completed measures of psychological status,lumbar spine dysfunction,and quality of life.A latent class growth model was used to analyze the post-LIF trajectory of anxiety and depression levels,and unordered multi-categorical logistic regression was used to analyze the influencing factors.RESULTS Three trajectories of change in anxiety level were identified:Increasing anxiety(n=26,10.88%),decreasing anxiety(n=27,11.30%),and stable anxiety(n=186,77.82%).Likewise,three trajectories of change in depression level were identified:Increasing depression(n=30,12.55%),decreasing depression(n=26,10.88%),and stable depression(n=183,76.57%).Regression analysis showed that having no partner,female sex,elevated Oswestry dysfunction index(ODI)scores,and reduced 36-Item Short Form Health Survey scores all contributed to increased anxiety levels,whereas female sex,postoperative opioid use,and elevated ODI scores all contributed to increased depression levels.CONCLUSION During clinical observation,combining factors to predict anxiety and depression in post-LIF elderly patients enables timely intervention,quickens recovery,and enhances quality of life.
文摘BACKGROUND Salvage of the infected long stem revision total knee arthroplasty is challenging due to the presence of well-fixed ingrown or cemented stems.Reconstructive options are limited.Above knee amputation(AKA)is often recommended.We present a surgical technique that was successfully used on four such patients to convert them to a knee fusion(KF)using a cephalomedullary nail.CASE SUMMARY Four patients with infected long stem revision knee replacements that refused AKA had a single stage removal of their infected revision total knee followed by a KF.They were all treated with a statically locked antegrade cephalomedullary fusion nail,augmented with antibiotic impregnated bone cement.All patients had successful limb salvage and were ambulatory with assistive devices at the time of last follow-up.All were infection free at an average follow-up of 25.5 months(range 16-31).CONCLUSION Single stage cephalomedullary nailing can result in a successful KF in patients with infected long stem revision total knees.
基金funded by the European Union via the Euratom Research and Training Program(Grant Agreement No.101052200-EUROfusion)funding from LASERLAB-EUROPE(Grant Agreement No.871124,European Union’s Horizon 2020 Research and Innovation Program)+5 种基金supported in part by the United States Department of Energy under Grant No.DE-FG02-93ER40773We also acknowledge support from Grant No.PID2021-125389OA-I00 funded by MCIN/AEI/10.13039/501100011033/FEDER,UEby“ERDF A Way of Making Europe”by the European Union and Unidad de Investigación Consolidada of Junta de Castilla y León UIC 167supported in part by the National Natural Science Foundation of China under Grant No.12375125the Fundamental Research Funds for the Central Universitiesthe support of the Czech Science Foundation through Grant No.GACR24-11398S.
文摘Driving of the nuclear fusion reaction p+^(11)B3α+8.7 MeV under laboratory conditions by interaction between high-power laser pulses and matter has become a popular field of research,owing to its numerous potential applications:as an alternative to deuterium-tritium for fusion energy production,astrophysics studies,and alpha-particle generation for medical treatment.One possible scheme for laser-driven p-^(11)B reactions is to direct a beam of laser-accelerated protons onto a boron(B)sample(the so-called“pitcher-catcher”scheme).This technique has been successfully implemented on large high-energy lasers,yielding hundreds of joules per shot at low repetition.We present here a complementary approach,exploiting the high repetition rate of the VEGA III petawatt laser at CLPU(Spain),aiming at accumulating results from many interactions at much lower energy,to provide better control of the parameters and the statistics of the measurements.Despite a moderate energy per pulse,our experiment allowed exploration of the laser-driven fusion process with tens(up to hundreds)of laser shots.The experiment provided a clear signature of the reactions involved and of the fusion products,accumulated over many shots,leading to an improved optimization of the diagnostics for experimental campaigns of this type.In this paper,we discuss the effectiveness of laser-driven p-11B fusion in the pitcher-catcher scheme,at a high repetition rate,addressing the challenges of this experimental scheme and highlighting its critical aspects.Our proposed methodology allows evaluation of the performance of this scheme for laser-driven alpha particle production and can be adapted to high-repetition-rate laser facilities with higher energy and intensity.
基金supported by the National Natural Science Foundation of China(No.62241109)the Tianjin Science and Technology Commissioner Project(No.20YDTPJC01110)。
文摘An improved model based on you only look once version 8(YOLOv8)is proposed to solve the problem of low detection accuracy due to the diversity of object sizes in optical remote sensing images.Firstly,the feature pyramid network(FPN)structure of the original YOLOv8 mode is replaced by the generalized-FPN(GFPN)structure in GiraffeDet to realize the"cross-layer"and"cross-scale"adaptive feature fusion,to enrich the semantic information and spatial information on the feature map to improve the target detection ability of the model.Secondly,a pyramid-pool module of multi atrous spatial pyramid pooling(MASPP)is designed by using the idea of atrous convolution and feature pyramid structure to extract multi-scale features,so as to improve the processing ability of the model for multi-scale objects.The experimental results show that the detection accuracy of the improved YOLOv8 model on DIOR dataset is 92%and mean average precision(mAP)is 87.9%,respectively 3.5%and 1.7%higher than those of the original model.It is proved the detection and classification ability of the proposed model on multi-dimensional optical remote sensing target has been improved.
基金partially supported by the National Natural Science Foundation of China under Grants 62471493 and 62402257(for conceptualization and investigation)partially supported by the Natural Science Foundation of Shandong Province,China under Grants ZR2023LZH017,ZR2024MF066,and 2023QF025(for formal analysis and validation)+1 种基金partially supported by the Open Foundation of Key Laboratory of Computing Power Network and Information Security,Ministry of Education,Qilu University of Technology(Shandong Academy of Sciences)under Grant 2023ZD010(for methodology and model design)partially supported by the Russian Science Foundation(RSF)Project under Grant 22-71-10095-P(for validation and results verification).
文摘To address the challenge of missing modal information in entity alignment and to mitigate information loss or bias arising frommodal heterogeneity during fusion,while also capturing shared information acrossmodalities,this paper proposes a Multi-modal Pre-synergistic Entity Alignmentmodel based on Cross-modalMutual Information Strategy Optimization(MPSEA).The model first employs independent encoders to process multi-modal features,including text,images,and numerical values.Next,a multi-modal pre-synergistic fusion mechanism integrates graph structural and visual modal features into the textual modality as preparatory information.This pre-fusion strategy enables unified perception of heterogeneous modalities at the model’s initial stage,reducing discrepancies during the fusion process.Finally,using cross-modal deep perception reinforcement learning,the model achieves adaptive multilevel feature fusion between modalities,supporting learningmore effective alignment strategies.Extensive experiments on multiple public datasets show that the MPSEA method achieves gains of up to 7% in Hits@1 and 8.2% in MRR on the FBDB15K dataset,and up to 9.1% in Hits@1 and 7.7% in MRR on the FBYG15K dataset,compared to existing state-of-the-art methods.These results confirm the effectiveness of the proposed model.
基金supported by the National Natural Science Foundation of China(Grant No.12104500)the Key Research and Development Projects of Shaanxi Province of China(Grant No.2023-YBSF-263).
文摘Fourier ptychographic microscopy(FPM)is an innovative computational microscopy approach that enables high-throughput imaging with high resolution,wide field of view,and quantitative phase imaging(QPI)by simultaneously capturing bright-field and dark-field images.However,effectively utilizing dark-field intensity images,including both normally exposed and overexposed data,which contain valuable high-angle illumination information,remains a complex challenge.Successfully extracting and applying this information could significantly enhance phase reconstruction,benefiting processes such as virtual staining and QPI imaging.To address this,we introduce a multi-exposure image fusion(MEIF)framework that optimizes dark-field information by incorporating it into the FPM preprocessing workflow.MEIF increases the data available for reconstruction without requiring changes to the optical setup.We evaluate the framework using both feature-domain and traditional FPM,demonstrating that it achieves substantial improvements in intensity resolution and phase information for biological samples that exceed the performance of conventional high dynamic range(HDR)methods.This image preprocessing-based information-maximization strategy fully leverages existing datasets and offers promising potential to drive advancements in fields such as microscopy,remote sensing,and crystallography.
基金supported by the National Natural Science Foundation of China(62276092,62303167)the Postdoctoral Fellowship Program(Grade C)of China Postdoctoral Science Foundation(GZC20230707)+3 种基金the Key Science and Technology Program of Henan Province,China(242102211051,242102211042,212102310084)Key Scientiffc Research Projects of Colleges and Universities in Henan Province,China(25A520009)the China Postdoctoral Science Foundation(2024M760808)the Henan Province medical science and technology research plan joint construction project(LHGJ2024069).
文摘Feature fusion is an important technique in medical image classification that can improve diagnostic accuracy by integrating complementary information from multiple sources.Recently,Deep Learning(DL)has been widely used in pulmonary disease diagnosis,such as pneumonia and tuberculosis.However,traditional feature fusion methods often suffer from feature disparity,information loss,redundancy,and increased complexity,hindering the further extension of DL algorithms.To solve this problem,we propose a Graph-Convolution Fusion Network with Self-Supervised Feature Alignment(Self-FAGCFN)to address the limitations of traditional feature fusion methods in deep learning-based medical image classification for respiratory diseases such as pneumonia and tuberculosis.The network integrates Convolutional Neural Networks(CNNs)for robust feature extraction from two-dimensional grid structures and Graph Convolutional Networks(GCNs)within a Graph Neural Network branch to capture features based on graph structure,focusing on significant node representations.Additionally,an Attention-Embedding Ensemble Block is included to capture critical features from GCN outputs.To ensure effective feature alignment between pre-and post-fusion stages,we introduce a feature alignment loss that minimizes disparities.Moreover,to address the limitations of proposed methods,such as inappropriate centroid discrepancies during feature alignment and class imbalance in the dataset,we develop a Feature-Centroid Fusion(FCF)strategy and a Multi-Level Feature-Centroid Update(MLFCU)algorithm,respectively.Extensive experiments on public datasets LungVision and Chest-Xray demonstrate that the Self-FAGCFN model significantly outperforms existing methods in diagnosing pneumonia and tuberculosis,highlighting its potential for practical medical applications.
基金supported in part by the National Key R&D Program of China(Grant No.2023YFB3307604)the Shanxi Province Basic Research Program Youth Science Research Project(Grant Nos.202303021212054 and 202303021212046)+3 种基金the Key Projects Supported by Hebei Natural Science Foundation(Grant No.E2024203125)the National Science Foundation of China(Grant No.52105391)the Hebei Provincial Science and Technology Major Project(Grant No.23280101Z)the National Key Laboratory of Metal Forming Technology and Heavy Equipment Open Fund(Grant No.S2308100.W17).
文摘A novel dual-branch decoding fusion convolutional neural network model(DDFNet)specifically designed for real-time salient object detection(SOD)on steel surfaces is proposed.DDFNet is based on a standard encoder–decoder architecture.DDFNet integrates three key innovations:first,we introduce a novel,lightweight multi-scale progressive aggregation residual network that effectively suppresses background interference and refines defect details,enabling efficient salient feature extraction.Then,we propose an innovative dual-branch decoding fusion structure,comprising the refined defect representation branch and the enhanced defect representation branch,which enhance accuracy in defect region identification and feature representation.Additionally,to further improve the detection of small and complex defects,we incorporate a multi-scale attention fusion module.Experimental results on the public ESDIs-SOD dataset show that DDFNet,with only 3.69 million parameters,achieves detection performance comparable to current state-of-the-art models,demonstrating its potential for real-time industrial applications.Furthermore,our DDFNet-L variant consistently outperforms leading methods in detection performance.The code is available at https://github.com/13140W/DDFNet.
基金supported by the National Natural Science Foundation of China(Grant No.62302086)the Natural Science Foundation of Liaoning Province(Grant No.2023-MSBA-070)the Fundamental Research Funds for the Central Universities(Grant No.N2317005).
文摘Visible-infrared object detection leverages the day-night stable object perception capability of infrared images to enhance detection robustness in low-light environments by fusing the complementary information of visible and infrared images.However,the inherent differences in the imaging mechanisms of visible and infrared modalities make effective cross-modal fusion challenging.Furthermore,constrained by the physical characteristics of sensors and thermal diffusion effects,infrared images generally suffer from blurred object contours and missing details,making it difficult to extract object features effectively.To address these issues,we propose an infrared-visible image fusion network that realizesmultimodal information fusion of infrared and visible images through a carefully designedmultiscale fusion strategy.First,we design an adaptive gray-radiance enhancement(AGRE)module to strengthen the detail representation in infrared images,improving their usability in complex lighting scenarios.Next,we introduce a channelspatial feature interaction(CSFI)module,which achieves efficient complementarity between the RGB and infrared(IR)modalities via dynamic channel switching and a spatial attention mechanism.Finally,we propose a multi-scale enhanced cross-attention fusion(MSECA)module,which optimizes the fusion ofmulti-level features through dynamic convolution and gating mechanisms and captures long-range complementary relationships of cross-modal features on a global scale,thereby enhancing the expressiveness of the fused features.Experiments on the KAIST,M3FD,and FLIR datasets demonstrate that our method delivers outstanding performance in daytime and nighttime scenarios.On the KAIST dataset,the miss rate drops to 5.99%,and further to 4.26% in night scenes.On the FLIR and M3FD datasets,it achieves AP50 scores of 79.4% and 88.9%,respectively.
文摘This paper presents an enhanced version of the correlation-driven dual-branch feature decomposition framework(CDDFuse)for fusing low-and high-exposure images captured by the G400BSI sensor.We introduce a novel neural long-term memory(NLM)module into the CDDFuse architecture to improve feature extraction by leveraging persistent global feature representations across image sequences.The proposed method effectively preserves dynamic range and structural details,and is evaluated using a new metric,the ATEF dynamic range preservation index(ATEF-DRPI).Experimental results on a G400BSI dataset demonstrate superior fusion quality,with ATEF-DRPI scores of 0.90,a 12.5%improvement over that of the baseline CDDFuse(0.80),indicating better detail retention in bright and dark regions.This work advances image fusion techniques for extreme lighting conditions,offering improved performance for downstream vision tasks.
基金supported by the National Natural Science Foundation of China(NSFC)(Grant Nos.12074399,12204500,and 12004403)the Key Projects of the Intergovernmental International Scientifi and Technological Innovation Cooperation(Grant No.2021YFE0116700)+1 种基金the Shanghai Natural Science Foundation(Grant No.20ZR1464400)the Shanghai Sailing Program(Grant No.22YF1455300)。
文摘The effect of drive laser wavelength on the growth of ablative Rayleigh–Taylor instability(ARTI)in inertial confinemen fusion(ICF)is studied with two-dimensional numerical simulations.The results show that in the plasma acceleration phase,shorter wavelengths lead to more efficien coupling between the laser and the kinetic energy of the implosion fluid Under the condition that the laser energy coupled to the implosion flui is constant,the ARTI growth rate decreases as the laser wavelength moves toward the extreme ultraviolet band,reaching its minimum value near λ=65 nm,and when the laser wavelength continuously moves toward the X-ray band,the ARTI growth rate increases rapidly.It is found that the results deviate from the theoretical ARTI growth rate.As the laser intensity benchmark increases,the position of the minimum ARTI growth rate shifts toward shorter wavelengths.As the initial sinusoidal perturbation wavenumber decreases,the position of the minimum ARTI growth rate shifts toward longer wavelengths.We believe that the conclusions drawn from the present simulations and analysis will help provide a better understanding of the ICF process and improve the theory of ARTI growth.
基金funded by the National Key R&D Program of China(Grant No.2023YFA1608400)the National Natural Science Foundation of China(Grant No.12302281).
文摘Hydrodynamic instability growth at the deuterium-tritium(DT)fuel-ablator interface plays a critical role in determining the performance of inertial confinement fusion implosions.During the late stages of implosion,insufficient doping of the ablator material can result in highenergy X-ray preheat,which may trigger the development of a classical-like Rayleigh-Taylor instability(RTI)at the fuel-ablator interface.In implosion experiments at the Shenguang 100 kJ-level laser facility,the primary source of perturbation is the roughness of the inner DT ice interface.In this study,we propose an analytical model to describe the feed-out process of the initial roughness of the inner DT ice interface.The perturbation amplitude derived from this model serves as the initial seed for the late-time RTI during the acceleration phase.Our findings confirm the presence of classical-like RTI at the fuel-ablator interface.Numerical simulations conducted using a radiation hydrodynamic code validate the proposed analytical model and demonstrate the existence of a peak mode number in both the feed-out process and the classical-like RTI.It provides an alternative bridge between the current target fabrication limitations and the unexpected implosion performance.
基金supported by Universiti Teknologi MARA through UiTM MyRA Research Grant,600-RMC 5/3/GPM(053/2022).
文摘Infrared and visible image fusion technology integrates the thermal radiation information of infrared images with the texture details of visible images to generate more informative fused images.However,existing methods often fail to distinguish salient objects from background regions,leading to detail suppression in salient regions due to global fusion strategies.This study presents a mask-guided latent low-rank representation fusion method to address this issue.First,the GrabCut algorithm is employed to extract a saliency mask,distinguishing salient regions from background regions.Then,latent low-rank representation(LatLRR)is applied to extract deep image features,enhancing key information extraction.In the fusion stage,a weighted fusion strategy strengthens infrared thermal information and visible texture details in salient regions,while an average fusion strategy improves background smoothness and stability.Experimental results on the TNO dataset demonstrate that the proposed method achieves superior performance in SPI,MI,Qabf,PSNR,and EN metrics,effectively preserving salient target details while maintaining balanced background information.Compared to state-of-the-art fusion methods,our approach achieves more stable and visually consistent fusion results.The fusion code is available on GitHub at:https://github.com/joyzhen1/Image(accessed on 15 January 2025).
基金supported by JSPS,MEXT,CORE(Center for Optical Research and Education,Utsunomiya University),ASHULA,ILE/Osaka University,and CDI(Cre-ative Department for Innovation,Utsunomiya University).
文摘In this review paper on heavy ion inertial fusion(HIF),the state-of-the-art scientific results are presented and discussed on the HIF physics,including physics of the heavy ion beam(HIB)transport in a fusion reactor,the HIBs-ion illumination on a direct-drive fuel target,the fuel target physics,the uniformity of the HIF target implosion,the smoothing mechanisms of the target implosion non-uniformity and the robust target implosion.The HIB has remarkable preferable features to release the fusion energy in inertial fusion:in particle accelerators HIBs are generated with a high driver efficiency of~30%-40%,and the HIB ions deposit their energy inside of materials.Therefore,a requirement for the fusion target energy gain is relatively low,that would be~50-70 to operate a HIF fusion reactor with the standard energy output of 1 GWof electricity.The HIF reactor operation frequency would be~10-15 Hz or so.Several-MJ HIBs illuminate a fusion fuel target,and the fuel target is imploded to about a thousand times of the solid density.Then the DT fuel is ignited and burned.The HIB ion deposition range is defined by the HIB ions stopping length,which would be~1 mm or so depending on the material.Therefore,a relatively large density-scale length appears in the fuel target material.One of the critical issues in inertial fusion would be a spherically uniform target compression,which would be degraded by a non-uniform implosion.The implosion non-uniformity would be introduced by the Rayleigh-Taylor(R-T)instability,and the large densitygradient-scale length helps to reduce the R-T growth rate.On the other hand,the large scale length of the HIB ions stopping range suggests that the temperature at the energy deposition layer in a HIF target does not reach a very-high temperature:normally about 300 eV or so is realized in the energy absorption region,and that a direct-drive target would be appropriate in HIF.In addition,the HIB accelerators are operated repetitively and stably.The precise control of the HIB axis manipulation is also realized in the HIF accelerator,and the HIB wobbling motion may give another tool to smooth the HIB illumination non-uniformity.The key issues in HIF physics are also discussed and presented in the paper.
文摘Signal transducer and activator of transcription（STAT）is a unique protein family that binds to DNA,coupled with tyrosine phosphorylation signaling pathways,acting as a transcriptional regulator to mediate a variety of biological effects.Cerebral ischemia and reperfusion can activate STATs signaling pathway,but no studies have confirmed whether STAT activation can be verified by diffusion-weighted magnetic resonance imaging（DWI）in rats after cerebral ischemia/reperfusion.Here,we established a rat model of focal cerebral ischemia injury using the modified Longa method.DWI revealed hyperintensity in parts of the left hemisphere before reperfusion and a low apparent diffusion coefficient.STAT3 protein expression showed no significant change after reperfusion,but phosphorylated STAT3 expression began to increase after 30 minutes of reperfusion and peaked at 24 hours.Pearson correlation analysis showed that STAT3 activation was correlated positively with the relative apparent diffusion coefficient and negatively with the DWI abnormal signal area.These results indicate that DWI is a reliable representation of the infarct area and reflects STAT phosphorylation in rat brain following focal cerebral ischemia/reperfusion.
