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FORTUNE COMES FROM BRAND ARTISTIC WORK FUSES IN GLASSWARE--Cheng Mingsen,General manager of Xi'an Freedragon Enterprises Co.,Ltd.,on how to deal with international market for mainland enterprises
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《China's Foreign Trade》 2002年第7期58-59,共2页
关键词 on how to deal with international market for mainland enterprises FORTUNE COMES FROM BRAND ARTISTIC WORK fuses IN GLASSWARE Ltd
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SEPW-the Cradle of Surge Arresters and Fuses in China
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作者 Wang YongliangShanghai Electric Porcelain Works 《Electricity》 1996年第1期40-43,共4页
Shanghai Electric Porcelain Works (SEPW), a subsidiary enterprise of the SEC (Group), is specialized in manufacturing highvoltage surge arresters and fuses as main products, as well as some high-voltage insulators, wa... Shanghai Electric Porcelain Works (SEPW), a subsidiary enterprise of the SEC (Group), is specialized in manufacturing highvoltage surge arresters and fuses as main products, as well as some high-voltage insulators, wall bushings and disconnecting switches for power transmission & distribution systems. In fact, SEPW is 展开更多
关键词 MOA SEPW-the Cradle of Surge Arresters and fuses in China HIGH SIC
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Seismic design or retrofit of buildings with metallic structural fuses by the damage-reduction spectrum 被引量:3
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作者 Li Gang Jiang Yi +2 位作者 Zhang Shuchuan Zeng Yan Li Qiang 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2015年第1期85-96,共12页
Recently, the structural fuse has become an important issue in the field of earthquake engineering. Due to the trilinearity of the pushover curve of buildings with metallic structural fuses, the mechanism of the struc... Recently, the structural fuse has become an important issue in the field of earthquake engineering. Due to the trilinearity of the pushover curve of buildings with metallic structural fuses, the mechanism of the structural fuse is investigated through the ductility equation of a single-degree-of-freedom system, and the corresponding damage-reduction spectrum is proposed to design and retrofit buildings. Furthermore, the controlling parameters, the stiffness ratio between the main frame and structural fuse and the ductility factor of the main frame, are parametrically studied, and it is shown that the structural fuse concept can be achieved by specific combinations of the controlling parameters based on the proposed damage-reduction spectrum. Finally, a design example and a retrofit example, variations of real engineering projects after the 2008 Wenchuan earthquake, are provided to demonstrate the effectiveness of the proposed design procedures using buckling restrained braces as the structural fuses. 展开更多
关键词 seismic design structural fuse damage-reduction spectrum RETROFIT
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Controlled rocking pile foundation system with replaceable bar fuses for seismic resilience 被引量:3
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作者 Cheng Zhao Li Shuai Wang Jingquan 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2022年第3期683-696,共14页
Bridges designed following a conventional approach minimize the risk of collapse,but often require challenging,costly,and time-consuming restoration after an earthquake occurs.The new seismic design philosophy require... Bridges designed following a conventional approach minimize the risk of collapse,but often require challenging,costly,and time-consuming restoration after an earthquake occurs.The new seismic design philosophy requires bridges to maintain functionality even after severe earthquakes.In this context,this paper proposes a controlled rocking pile foundation(CRPF)system and numerically evaluates bridges′degree of seismic resilience.The CRPF system allows a pile cap to rock on a pile foundation and dissipate seismic energy through inelastic deformations of replaceable bar fuses that connect a pile cap and piles.Following the conceptual design of the CRPF system,two analytical models were developed for a bridge pier utilizing the CRPF system and a pier designed to develop a plastic hinge in its column.The analytical results indicate that,after experiencing a severe earthquake,a conventionally designed bridge pier sustained substantial damage in its column and exhibited significant residual displacement.In contrast,a pier using the CRPF system showed negligible residual displacement and maintained elastic behavior except,as expected,for bar fuses.The damaged fuses can be rapidly replaced to recover bridge seismic resistance following an earthquake.Therefore,the CRPF system helps to achieve the desired postearthquake performance objectives. 展开更多
关键词 seismic resilience bridges pier controlled rocking pile foundation repairable bar fuse
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Steel rings as seismic fuses for enhancing ductility of cross braced frames 被引量:2
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作者 Farhad Behnamfar Saeid Arman Hassan Zibasokhan 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2022年第4期1103-1117,共15页
A new remedy is proposed in this study to increase the ductility of cross-braced frames to a level comparable with ductile moment frames.The suggested system consists of one or two concentric steel rings installed in ... A new remedy is proposed in this study to increase the ductility of cross-braced frames to a level comparable with ductile moment frames.The suggested system consists of one or two concentric steel rings installed in the cross-braced bay vertically.The steel rings are designed such that they fail in bending sooner than failure of the braces in compression.Then the rings act as seismic fuses with multiple bending plastic hinges.Using nonlinear static analysis,it is shown that the proposed system can be designed to behave like cross-braced frames with regard to stiffness and strength,and like special moment frames with regard to ductility.Seismic design factors for the proposed system are recommended based on nonlinear pushover and cyclic analysis studies. 展开更多
关键词 cross brace special moment frame steel ring seismic fuse DUCTILITY
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Study on detonation velocity deficits of bending flexible detonation fuses 被引量:1
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作者 叶耀坤 温玉全 严楠 《Journal of Beijing Institute of Technology》 EI CAS 2011年第4期427-432,共6页
In order to study the detonation velocity deficits of bending flexible detonating fuses,a physical model and a theoretical mathematical equation of detonation velocity deficits for bending flexible detonation fuses we... In order to study the detonation velocity deficits of bending flexible detonating fuses,a physical model and a theoretical mathematical equation of detonation velocity deficits for bending flexible detonation fuses were established based on the detonation wave's corner effects and delay time phenomenon by using non-dimensional analysis method.Besides,a semi-empirical formula of detonation velocity deficit for bending fuses in the same charge size was obtained through experiment and curve fitting.The result shows that an exponential relationship between the detonation velocity deficits and reciprocal of curvature radius. 展开更多
关键词 flexible detonating fuse detonation velocity deficits curvature radius delay time
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Broken and fine powder detection method of fuses
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作者 李士林 王明泉 +1 位作者 李高亮 侯慧玲 《Journal of Measurement Science and Instrumentation》 CAS 2012年第2期116-118,共3页
Since powder and cotton wool may cause mechanical test fail,and the accuracy of ray detection method is not very ideal,this paper introduces the tiny capacitance detection method for broken gunpowder,in which the medi... Since powder and cotton wool may cause mechanical test fail,and the accuracy of ray detection method is not very ideal,this paper introduces the tiny capacitance detection method for broken gunpowder,in which the medium type capacitive sensor’s capacitance changes when the gunpowder core diameter changes.The detection is based on the relationship between non-electric quantity and electric quantity.Simulation results show that the designed system works well with easy installation and low power consumption.Therefore,it is suitable for broken gunpowder detection. 展开更多
关键词 FUSE power detection tiny capacitance detection
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Effect of Design Parameters on the Properties of PLA Biocomposites Fabricated via Fused Filament Deposition
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作者 Martha L.Sánchez Luz Y.Morales Gil Capote 《Journal of Renewable Materials》 2025年第7期1413-1437,共25页
The use of additive manufacturing techniques in the development of unconventional materials can help reduce the environmental impact of traditional construction materials.In this paper,the properties of a 3D-printed b... The use of additive manufacturing techniques in the development of unconventional materials can help reduce the environmental impact of traditional construction materials.In this paper,the properties of a 3D-printed biocomposite were evaluated.Biofilaments obtained by mixing pulverized bamboo fibers with polylactic acid(PLA)resin were extruded during the manufacturing process.To assess the effect of incorporating plant fibers,an analysis was conducted on the morphology,elemental chemical composition,crystallinity index,principal functional groups,thermal stability,surface roughness,microhardness,density,tensile strength,elastic modulus,and strain percentage of reinforced samples.The results were comparedwith those obtained from the characterization of standard PLAfilaments(unreinforced).The fused deposition modeling(FDM)technique was employed to print biocomposite specimens.Additionally,the influence of the printing parameters(infill density,build orientation,and layer thickness)on the physical,tribological,andmechanical properties of the biocomposites was analyzed.These results were compared with those obtained for specimens printed with pure PLA.The findings indicate that incorporating 10%vegetable filler into PLA filaments enhanced the strength and stiffness of the biocomposite under axial loads.Finally,the strength of the biocomposite subjected to axial loads was compared with the standardized values for wood-plastic composites,demonstrating the feasibility of its use for non-structural purposes in civil construction. 展开更多
关键词 BIOCOMPOSITES biofilaments 3D printing fused deposition modeling printing parameters mechanical properties
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Strain rate effects on pressure-induced amorphous-to-amorphous transformation in fused silica
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作者 Wenhao Song Bo Gan +3 位作者 Dongxiao Liu Jie Wu Martin T.Dove Youjun Zhang 《Chinese Physics B》 2025年第4期71-76,共6页
Fused silica(SiO_(2)glass),a key amorphous component of Earth’s silicate minerals,undergoes coordination and phase transformations under high pressure.Although extensive studies have been conducted,discrepancies betw... Fused silica(SiO_(2)glass),a key amorphous component of Earth’s silicate minerals,undergoes coordination and phase transformations under high pressure.Although extensive studies have been conducted,discrepancies between theoretical and experimental studies remain,particularly regarding strain rate effects during compression.Here,we examine strain rate influences on the shock-induced amorphous–amorphous phase transitions in fused silica by measuring its Hugoniot equation of state and longitudinal sound velocity(CL)up to 7 GPa at strain rates of 10^(6)–10^(7)s^(-1)using a one-stage light-gas gun.A discontinuity in the relationship between shock velocity(US)and particle velocity(UP)and a significant softening in C_(L)of fused silica were observed near~5 GPa under shock loading.Our results indicate that high strain rates restrict Si–O–Si rotation in fused silica,modifying their bonds and increasing silicon coordination.The transition pressure by shock compression is significantly higher than that under static high-pressure conditions(2–3 GPa),which agrees with some recent theoretical predictions with high compression rates,reflecting the greater pressure needed to overcome energy barriers with the strain rate increase.These findings offer insights into strain rate-dependent phase transitions in fused silica and other silicate minerals(e.g.,quartz,olivine,and forsterite),bridging gaps between theoretical simulations and experiments. 展开更多
关键词 fused silica shock compression phase transition kinetics strain rate
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Balanced Optimization of Dimensional Accuracy and Printing Efficiency in FDM Based on Data-Driven Modeling
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作者 Liu Changhui Li Hao +5 位作者 Yu Chunlong Liao Xueru Liu Xiaojia Sun Jianzhi Tang Qirong Yu Min 《Additive Manufacturing Frontiers》 2025年第2期97-110,共14页
Additive manufacturing(AM),particularly fused deposition modeling(FDM),has emerged as a transformative technology in modern manufacturing processes.The dimensional accuracy of FDM-printed parts is crucial for ensuring... Additive manufacturing(AM),particularly fused deposition modeling(FDM),has emerged as a transformative technology in modern manufacturing processes.The dimensional accuracy of FDM-printed parts is crucial for ensuring their functional integrity and performance.To achieve sustainable manufacturing in FDM,it is necessary to optimize the print quality and time efficiency concurrently.However,owing to the complex interactions of printing parameters,achieving a balanced optimization of both remains challenging.This study examines four key factors affecting dimensional accuracy and print time:printing speed,layer thickness,nozzle temperature,and bed temperature.Fifty parameter sets were generated using enhanced Latin hypercube sampling.A whale optimization algorithm(WOA)-enhanced support vector regression(SVR)model was developed to predict dimen-sional errors and print time effectively,with non-dominated sorting genetic algorithm Ⅲ(NSGA-Ⅲ)utilized for multi-objective optimization.The technique for Order Preference by Similarity to Ideal Solution(TOPSIS)was applied to select a balanced solution from the Pareto front.In experimental validation,the parts printed using the optimized parameters exhibited excellent dimensional accuracy and printing efficiency.This study comprehensively considered optimizing the printing time and size to meet quality requirements while achieving higher printing efficiency and aiding in the realization of sustainable manufacturing in the field of AM.In addition,the printing of a specific prosthetic component was used as a case study,highlighting the high demands on both dimensional precision and printing efficiency.The optimized process parameters required significantly less printing time,while satisfying the dimensional accuracy requirements.This study provides valuable insights for achieving sustainable AM using FDM. 展开更多
关键词 Fused deposition modeling Dimensional accuracy Process parameters Printing efficiency Balanced optimization Sustainable manufacturing
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Undrained cyclic simple shear characteristics of transparent sand manufactured by fused quartz
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作者 ZHAO Jin-qiao OU Qiang +4 位作者 JIANG Chun-yong DING Xuan-ming ZHOU Hang YANG Chang-wei DENG Wei-ting 《Journal of Central South University》 2025年第9期3427-3446,共20页
Transparent sand is a special material to realize visualization of concealed work in geotechnical engineering. To investigate the dynamic characteristics of transparent sand, a series of undrained cyclic simple shear ... Transparent sand is a special material to realize visualization of concealed work in geotechnical engineering. To investigate the dynamic characteristics of transparent sand, a series of undrained cyclic simple shear tests were conducted on the saturated transparent sand composed of fused quartz and refractive index-matched oil mixture. The results reveal that an increase in the initial shear stress ratio significantly affects the shape of the hysteresis loop, particularly resulting in more pronounced asymmetrical accumulation. Factors such as lower relative density, higher cyclic stress ratios and higher initial shear stress ratio have been shown to accelerate cyclic deformation, cyclic pore water pressure and stiffness degradation. The cyclic liquefaction resistance curves decrease as the initial shear stress ratio increases or as relative density decreases. Booker model and power law function model were applied to predict the pore water pressure for transparent sand. Both models yielded excellent fits for their respective condition, indicating a similar dynamic liquefaction pattern to that of natural sands. Finally, transparent sand displays similar dynamic characteristics in terms of cyclic liquefaction resistance and Kα correction factor. These comparisons indicate that transparent sand can serve as an effective means to mimic many natural sands in dynamic model tests. 展开更多
关键词 transparent sand fused quartz undrained cyclic simple shear tests dynamic characteristics initial shear stress
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Macroscopic and Microscopic Residual Stresses in Nickel-Aluminum Bronze Matrix Composite Surface Deposits Manufactured via Laser Melt Injection
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作者 X.X.Zhang E.Walz +6 位作者 A.Langebeck J.Rebelo Kornmeier A.Kriele V.Luzin M.Adveev A.Bohlen M.Hofmann 《Acta Metallurgica Sinica(English Letters)》 2025年第4期570-586,共17页
Wear is a prevalent issue across various industries. Spherical fused tungsten carbide (sFTC) reinforced nickel-aluminum bronze (NAB) matrix composite surface deposits have shown remarkable potential in mitigating wear... Wear is a prevalent issue across various industries. Spherical fused tungsten carbide (sFTC) reinforced nickel-aluminum bronze (NAB) matrix composite surface deposits have shown remarkable potential in mitigating wear by approximately 80%. However, the performance of these sFTC/NAB composite surface deposits is determined by their residual stress state, and the precise macroscopic and microscopic residual stresses within these composites have yet to be clearly established. To address this gap, we employed neutron diffraction to measure the residual stresses in the sFTC/NAB composite surface deposits and re-melted NAB samples produced via laser melt injection. Significant residual stresses were determined. The maximum tensile macro residual stress appears approximately 1-1.5 mm below the composite layer. Residual stresses accumulate with an increasing number of laser process tracks. The maximum tensile macro residual stress in the three-track samples reaches about 350 MPa. Preheating the base plate significantly reduces the levels of macroscopic residual stress. The WC phase displayed significant compressive thermal misfit residual stress magnitude, while the Cu matrix exhibited tensile thermal misfit residual stress. Preheating the base plate does not reduce microscopic thermal misfit residual stress levels. In addition, a finite element model was built to investigate temperature and residual stresses in the re-melted NAB samples. The predicted temperature history and residual stress agree with the experimental results. 展开更多
关键词 Residual stress Neutron diffraction Laser melt injection Nickel-aluminum bronze Spherical fused tungsten carbide
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Preparation and Properties of Acrylonitrile Butadiene Styrene/Polycarbonate Composite Filament for Fused Deposition Modeling
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作者 Shanlong Che Guangliang Qu +3 位作者 Jin Ding Guochen Wang Yunyan Hao Dianchen Li 《Journal of Polymer Materials》 2025年第1期221-236,共16页
Acrylonitrile–butadiene–styrene(ABS)is the main material used in fused deposition modeling(FDM),which has good toughness and strength,but the single ABS material has poor heat resistance,which tends to cause warping... Acrylonitrile–butadiene–styrene(ABS)is the main material used in fused deposition modeling(FDM),which has good toughness and strength,but the single ABS material has poor heat resistance,which tends to cause warping and deformation during the printing process.Polycarbonate(PC)exhibits good performance in heat resistance,allowing it to maintain stable performance at higher temperatures.In this work,PC was used as a blending modifier to prepare five kinds of ABS/PC composite filaments,and the mechanical and thermal properties of the ABS/PC(Acrylonitrile-butadiene-styrene/Polycarbonate)composite filaments were studied and analyzed.Results showed that the glass transition temperature(Tg)of the blend increased continuously as the PC content increased.When the mass fraction of ABS/PC was 50/50,the glass transition temperature of the blend increased by 21.21%,and the tensile strength of the composites reached 40.23 MPa,which was an increase of 36.47% compared with that of pure ABS.However,the impact strength of the composites decreased with the addition of PC.Moreover,with the increase in the mass fraction of PC,the printing accuracy error increased from 0.02 to 0.18 mm.The results of this paper will promote the improvement of ABS printing performance and enrich the available materials for FDM. 展开更多
关键词 Fused deposition molding(FDM) acrylonitrile-butadiene-styrene(ABS) polycarbonate(PC) heat resistance mechanical property
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Abstracts Selected from Naihuo Cailiao(Refractories)——A Bimonthly in Chinese
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《China's Refractories》 2025年第2期49-54,共6页
Synthesis technology and properties of cordierite from solid waste resources/Tan Qitong,Zhao Huizhong,Yu Jun,Zhang Han,Tan Liqiang//Naihuo Cailiao.-2024,58(3):185 Abstract:To effectively utilize solid waste resources ... Synthesis technology and properties of cordierite from solid waste resources/Tan Qitong,Zhao Huizhong,Yu Jun,Zhang Han,Tan Liqiang//Naihuo Cailiao.-2024,58(3):185 Abstract:To effectively utilize solid waste resources and relieve resource constraints,cordierite refractory raw materials were prepared according to the chemical composition of cordierite,using 12 mass%fused magnesia dust powder,40 mass%fused corundum dust powder and 48 mass%quartz tailings as starting materials. 展开更多
关键词 corundum dust powder fused magnesia dust powder starting materials relieve resource constraintscordierite solid waste cordierite refractory raw materials raw materials solid waste resources
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Fluorinated fused azobenzene boron-based polymer acceptors with 1000 nm absorbance edges for all-polymer solar cells
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作者 Jiabin Zhang Xiaoke Zhang +3 位作者 Lilei Wang Lingpeng Yan Xueli Cheng Tao Li 《Chinese Chemical Letters》 2025年第7期533-537,共5页
Fluorinated fused azobenzene boron(FBAz)is a novel electron-deficient building block for polymer electron acceptors in all-polymer solar cells(all-PSC).The B←N bridging units impart a fixed configuration and low-lyin... Fluorinated fused azobenzene boron(FBAz)is a novel electron-deficient building block for polymer electron acceptors in all-polymer solar cells(all-PSC).The B←N bridging units impart a fixed configuration and low-lying LUMO/HOMO energy.Three polymer acceptor materials(P2f,P3f and P5f)with different fluorine substitution positions by copolymerizing FBAz with indacenodithiophene(IDT),are synthesized and investigated to study the influence of fluorinated forms on the all-polymer solar cell performance.The FBAz units are synthesized in just three steps,facilitating the straightforward production of polymer acceptors P2f,P3f,and P5f.These acceptors exhibit strong light absorption in the visible to near-infrared range of 500-1000nm and possess suitable LUMO/HOMO energy levels of-3.99/-5.66 eV which are very complementary to that(E_(LUMO/HOMO)=-3.59/-5.20 eV)of the widely-used polymer donor poly[(ethylhexylthiophenyl)-benzodithiophene-(ethylhexyl)-thienothiophene](PTB7-Th).All-polymer solar cells(all-PSCs)with PTB7-Th as electron donor and P3f as electron acceptor exhibits highest power conversion efficiencies(PCE)2.70%.When PC_(61)BM is added as the third component,the device efficiency can reach 5.36%.These preliminary results indicate that FBAz is a promising strong electron acceptor for the development of n-type polymer semiconductors,especially in organic photovoltaics(OPVs).To the best of our knowledge,this is the first example demonstrating the unique photovoltaic properties of the N=N double bond as an acceptor material. 展开更多
关键词 All-polymer solar cells Fluorinated fused azobenzene boron N=N double bond B←N coordination bond Near-infrared absorption
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A design strategy for long-term stability of porous PEEK implants by regulation of porous structure and in vivo mechanical stimulation
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作者 Yingjie Liu Ling Wang +9 位作者 Jie Zhang Shuguang Liu Jibao Zheng Jianfeng Kang Enchun Dong Changning Sun Ruhan A Chaozong Liu Chuncheng Yang Dichen Li 《Bio-Design and Manufacturing》 2025年第2期275-287,I0004,共14页
The bioinert nature of polyether ether ketone(PEEK)material limits the widespread clinical application of PEEK implants.Although the porous structure is considered to improve osseointegration of PEEK implants,it is ha... The bioinert nature of polyether ether ketone(PEEK)material limits the widespread clinical application of PEEK implants.Although the porous structure is considered to improve osseointegration of PEEK implants,it is hardly used due to its mechanical properties.This study investigated the combined influence of the porous structure and in vivo mechanical stimulation on implantation safety and bone growth based on finite element analysis of the biomechanical behavior of the implantation system.The combined control of pore size and screw preloads allows the porous PEEK implant to achieve good osseointegration while maintaining a relatively high safety level.A pore size of 600μm and a preload of 0.05 N·m are the optimal combination for the long-term stability of the implant,with which the safety factor of the implant is>2,and the predicted percentage of effective bone growth area of the bone-implant interface reaches 97%.For further clinical application,PEEK implants were fabricated with fused filament fabrication(FFF)three-dimensional(3D)printing,and clinical outcomes demonstrated better bone repair efficacy and long-term stability of porous PEEK implants compared to solid PEEK implants.Moreover,good osteointegration performance of 3D-printed porous PEEK implants was observed,with an average bone volume fraction>40%three months after implantation.In conclusion,3D-printed porous PEEK implants have great potential for clinical application,with validated implantation safety and good osseointegration. 展开更多
关键词 Porous polyether ether ketone(PEEK)implant OSTEOINTEGRATION Interface biomechanics Maxillofacial implants Finite element analyses Fused filament fabrication(FFF)3D printing
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Spatially random polarization-smoothing optics by residual stress birefringence of fused silica for laser-driven inertial confinement fusion
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作者 Chuanchao Zhang Wei Liao +6 位作者 Xiaolong Jiang Haijun Wang Fa Zeng Wei Ni Ping Li Xiaodong Jiang Qihua Zhu 《Matter and Radiation at Extremes》 2025年第5期54-63,共10页
We demonstrate a new polarization smoothing(PS)approach utilizing residual stress birefringence in fused silica to create a spatially random polarization control plate(SRPCP),thereby improving target illumination unif... We demonstrate a new polarization smoothing(PS)approach utilizing residual stress birefringence in fused silica to create a spatially random polarization control plate(SRPCP),thereby improving target illumination uniformity in inertial confinement fusion(ICF)laser systems.The fundamental operating mechanism and key fabrication techniques for the SRPCP are systematically developed and experimentally validated.The SRPCP converts a linearly polarized 3ω incident laser beam into an output beam with a spatially randomized polarization distribution.When combined with a continuous phase plate,the SRPCP effectively suppresses high-intensity speckles at all spatial frequencies in the focal spot.The proposed PS technique is specifically designed for high-fluence large-aperture laser systems,enabling novel polarization control regimes in laser-driven ICF. 展开更多
关键词 spatially ra fused silica spatially random polarization control plate srpcp thereby linearly polarized incident laser beam residual stress birefringence fabrication techniques improving target illumination uniformity spatially random polarization smoothing
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针灸预处理对胃溃疡大鼠胃黏膜状态及Gli 1/Gli 2/Sufu信号通路的影响研究 被引量:1
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作者 李盼 丁霞 +2 位作者 兰永利 韦芳 霍新慧 《四川中医》 2024年第2期77-82,共6页
目的:研究针灸预处理对胃溃疡大鼠胃黏膜状态及胶质瘤相关癌基因同源物1(Glioma-associated oncogene homolog 1,Gli1)/胶质瘤相关癌基因同源物2(Glioma-associated oncogene homolog 2,Gli2)/丝氨酸/苏氨酸激酶Fused抑制物(Sufu)信号... 目的:研究针灸预处理对胃溃疡大鼠胃黏膜状态及胶质瘤相关癌基因同源物1(Glioma-associated oncogene homolog 1,Gli1)/胶质瘤相关癌基因同源物2(Glioma-associated oncogene homolog 2,Gli2)/丝氨酸/苏氨酸激酶Fused抑制物(Sufu)信号通路的影响,探究针灸预防胃黏膜损伤的作用机制,为针灸在临床治疗胃溃疡疾病提供实验依据和理论支撑。方法:52只大鼠随机分为正常组、模型组、灸预处理组、针刺预处理组,每组13只。正常组、模型组只做固定;对灸预处理组和针刺预处理组艾灸中脘、足三里穴,每穴20min,1次/d,连续灸8d。之后对灸预处理组和针刺预处理组大鼠进行无水乙醇+阿司匹林混悬液灌胃造模。观察大鼠一般情况及胃黏膜组织病理学变化;酶联免疫吸附实验(ELISA)法检测大鼠血清中超氧化物歧化酶(SOD)、丙二醛(Malondialdehyde,MDA)、谷胱甘肽过氧化物酶(GPX)浓度,蛋白质印迹法(Western blot)分析大鼠胃黏膜组织Gli 1、Gli 2、Sufu蛋白表达。结果:模型组可见上皮细胞结构破坏不完整,胃黏膜组织损伤明显,UI指数评分显著高于正常组(P<0.05)。与正常组比较,模型组大鼠血清MDA、GPX浓度升高(P<0.05),SOD浓度降低(P<0.05);与模型组相比,针灸预处理组MDA、GPX浓度降低(P<0.05),SOD浓度增加(P<0.05);与正常组比较,模型组大鼠Gli1、Gli2、Sufu蛋白表达明显升高(P<0.05);与模型组比较,针灸预处理组大鼠Gli1、Gli2、Sufu蛋白表达明显降低(P<0.05)。结论:针灸预处理能改变胃溃疡大鼠胃黏膜状态,其机制可能与Gli 1/Gli 2/Sufu信号通路活化有关。 展开更多
关键词 针刺预处理 艾灸预处理 胃溃疡 胶质瘤相关癌基因同源物1/胶质瘤相关癌基因同源物2/丝氨酸/苏氨酸激酶Fused抑制物(Sufu) 大鼠
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Hemispherical resonator with low subsurface damage machined by small ball-end fine diamond grinding wheel:A novel grinding technique 被引量:1
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作者 Biao QIN Henan LIU +5 位作者 Jian CHENG Jinchuan TIAN Jiangang SUN Zihan ZHOU Chuanzhen MA Mingjun CHEN 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2024年第5期570-585,共16页
As for the ultra-precision grinding of the hemispherical fused silica resonator,due to the hard and brittle nature of fused silica,subsurface damage(SSD)is easily generated,which enormously influences the performance ... As for the ultra-precision grinding of the hemispherical fused silica resonator,due to the hard and brittle nature of fused silica,subsurface damage(SSD)is easily generated,which enormously influences the performance of such components.Hence,ultra-precision grinding experiments are carried out to investigate the surface/subsurface quality of the hemispherical resonator machined by the small ball-end fine diamond grinding wheel.The influence of grinding parameters on the surface roughness(SR)and SSD depth of fused silica samples is then analyzed.The experimental results indicate that the SR and SSD depth decreased with the increase of grinding speed and the decrease of feed rate and grinding depth.In addition,based on the material strain rate and the maximum undeformed chip thickness,the effect of grinding parameters on the subsurface damage mechanism of fused silica samples is analyzed.Furthermore,a multi-step ultra-precision grinding technique of the hemispherical resonator is proposed based on the interaction influence between grinding depth and feed rate.Finally,the hemispherical resonator is processed by the proposed grinding technique,and the SR is improved from 454.328 nm to 110.449 nm while the SSD depth is reduced by 94%from 40μm to 2.379μm.The multi-step grinding technique proposed in this paper can guide the fabrication of the hemispherical resonator. 展开更多
关键词 Fused silica Ultra-precision grinding Hemispherical resonator Subsurface damage Grinding technique
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Research on aiming methods for small sample size shooting tests of two-dimensional trajectory correction fuse 被引量:1
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作者 Chen Liang Qiang Shen +4 位作者 Zilong Deng Hongyun Li Wenyang Pu Lingyun Tian Ziyang Lin 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期506-517,共12页
The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction ... The longitudinal dispersion of the projectile in shooting tests of two-dimensional trajectory corrections fused with fixed canards is extremely large that it sometimes exceeds the correction ability of the correction fuse actuator.The impact point easily deviates from the target,and thus the correction result cannot be readily evaluated.However,the cost of shooting tests is considerably high to conduct many tests for data collection.To address this issue,this study proposes an aiming method for shooting tests based on small sample size.The proposed method uses the Bootstrap method to expand the test data;repeatedly iterates and corrects the position of the simulated theoretical impact points through an improved compatibility test method;and dynamically adjusts the weight of the prior distribution of simulation results based on Kullback-Leibler divergence,which to some extent avoids the real data being"submerged"by the simulation data and achieves the fusion Bayesian estimation of the dispersion center.The experimental results show that when the simulation accuracy is sufficiently high,the proposed method yields a smaller mean-square deviation in estimating the dispersion center and higher shooting accuracy than those of the three comparison methods,which is more conducive to reflecting the effect of the control algorithm and facilitating test personnel to iterate their proposed structures and algorithms.;in addition,this study provides a knowledge base for further comprehensive studies in the future. 展开更多
关键词 Two-dimensional trajectory correction fuse Small sample size test Compatibility test KL divergence Fusion bayesian estimation
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