目的:探讨特殊医学用途配方食品(food for special medical purpose,FSMP)营养治疗新路径在痔疮患者术后快速康复中的有效性。方法:选取2017-10-01~2018-05-31在我院肛肠外科进行手术治疗的男性混合痔疮患者60例,随机分为观察组及对照...目的:探讨特殊医学用途配方食品(food for special medical purpose,FSMP)营养治疗新路径在痔疮患者术后快速康复中的有效性。方法:选取2017-10-01~2018-05-31在我院肛肠外科进行手术治疗的男性混合痔疮患者60例,随机分为观察组及对照组。观察组采用FSMP营养治疗新路径进行营养干预,对照组采用一般术后快速康复饮食治疗,观察两组患者住院时间、首次排便时间、术后前3d平均排便次数、主观满意度、出院时营养状况及营养风险发生率、术后不良反应发生率等。结果:观察组住院时间、首次排便时间、术后前3d平均排便次数、出院时营养风险发生率及术后不良反应发生率(术后疼痛、出血、感染、低血糖)均明显低于对照组;观察组患者出院时营养状况及主观满意度明显高于对照组,差异均具有统计学意义(P<0.05或P<0.01)。结论:FSMP营养治疗新路径能加快痔疮患者术后快速康复,应在临床广泛推广。展开更多
Background and Objectives:Cancer patients at nutritional risk have a worse prognosis,but this can be im proved by nutritional support.Food for special medical purposes(FSMP),as a new form of nutritional support,needs ...Background and Objectives:Cancer patients at nutritional risk have a worse prognosis,but this can be im proved by nutritional support.Food for special medical purposes(FSMP),as a new form of nutritional support,needs to be further evaluated for its safety and efficacy in these patients.Our study elucidate the impact of FSMP on nutritional status and sarcopenia among nutritional risk cancer outpatients by assessing the NRS2002 score,exercise performance,muscle mass,and inflammatory factors pre-and postintervention.Methods and Study Design:We conducted a single-centre,double-blind,randomized controlled interventional study.Patients from the oncology clinic with nutritional risk were randomly allocated to the control group or the FSMP group and re ceived oral intervention for 8 weeks.The primary outcome was improvement in nutritional risk,while the sec ondary outcomes were improvements in sarcopenia prevalence and physical performance indicators.Other out comes included alterations in calf circumference,hsCRP,25(OH)VD3,Alb.etc.A linear mixed-effects model was used to compare the prepost-intervention changes in these results.Results:Thirty-six cancer patients were included,25 completed the study.The percentage of patients at nutritional risk after intervention in the FSMP group was significantly lower than the control group(Χ^(2)=4.186,p=0.041).The FSMP group demonstrated signif icant improvements in the TUG test,gait speed,grip strength,and upper-limb muscle mass.However,there was no significant improvement in the rate of sarcopenia.Moreover,calf circumference,hsCRP,25(OH)VD3,Alb exhibited no significant changes.Conclusions:FSMP can effectively improve the nutritional status,physical per formance and upper-limb muscle mass of cancer patients.展开更多
本研究旨在探究巴氏杀菌和超高温瞬时杀菌(Ultra-high Temperature Instantaneous Sterilization,UHT)以及不同喷雾干燥进口温度对特殊医学用途配方食品(Foods for Special Medical Purposes,FSMPs)粉体特性的影响。通过润湿性、分散性...本研究旨在探究巴氏杀菌和超高温瞬时杀菌(Ultra-high Temperature Instantaneous Sterilization,UHT)以及不同喷雾干燥进口温度对特殊医学用途配方食品(Foods for Special Medical Purposes,FSMPs)粉体特性的影响。通过润湿性、分散性、溶解性以及休止角、卡尔指数、豪斯那比,分别探究不同加工条件对粉体冲调性及流动性的影响;进一步通过水分含量及活度、粒径形态和表面成分揭示具体影响机制。结果显示:喷雾干燥进口温度为150℃时,UHT组样品的润湿时间相比于巴氏杀菌组显著缩短45.7%(P<0.05),水溶性指数显著升高13.8%(P<0.05),分散性指数显著降低16.1%(P<0.05)。喷雾干燥进口温度为170℃时,UHT组样品的卡尔指数和豪斯那比分别是巴氏杀菌组的59.3%和63.9%(P<0.05),水分含量是巴氏杀菌组81.4%(P<0.05),而平均粒径是巴氏杀菌组的1.94倍(P<0.05),扫描电镜下UHT组颗粒出现团聚现象,以及表面成分分析和激光共聚焦扫描显微镜结果显示UHT组表面脂质含量最高可达43.3%。随着喷雾干燥进口温度的升高,冲调性未呈现出显著变化趋势(P>0.05),而流动性呈现显著增加趋势(P<0.05)。综合来看,不同杀菌方式和喷雾干燥进口温度对特殊医学用途配方食品粉体冲调性和流动性、水分含量、粒径形态和表面脂质含量具有显著影响。本研究揭示了不同加工条件对于特殊医学用途配方食品粉体特性的影响及原因,为生产工艺的优化以及产品商业价值的提升提供理论指导。展开更多
本文从医学营养学视角出发,聚焦糖尿病与慢性肾病(Chronic Kidney Disease, CKD)两类高发慢性病患者,深入探讨其专用预制菜(Specialized Prepared Meals for Patients with Specific Diseases, SPM-PSD)的发展路径。系统分析了糖尿病与...本文从医学营养学视角出发,聚焦糖尿病与慢性肾病(Chronic Kidney Disease, CKD)两类高发慢性病患者,深入探讨其专用预制菜(Specialized Prepared Meals for Patients with Specific Diseases, SPM-PSD)的发展路径。系统分析了糖尿病与CKD患者的核心营养需求及当前市场供给中的关键问题,明确了基于医学机制(如最新疾病营养指南)与工艺创新的研发思路,探讨了智能化技术应用与产业链协同的实践策略,梳理了政策支持对这一细分市场发展的推动作用。本文旨在为医疗机构将糖尿病、CKD患者的营养干预方案有效融入家庭餐桌提供理论支持与实践指导,助力实现国家“食养医防”全民健康战略目标。展开更多
随着社会经济的发展和生活水平的提高,人们对营养与健康日渐重视。特殊医学用途配方食品(Food for special medical purposes,FSMPs)能够为特定疾病或医学状况的人群提供专门摄取的营养或膳食需求,进而达到改善特殊人群患者营养不良状...随着社会经济的发展和生活水平的提高,人们对营养与健康日渐重视。特殊医学用途配方食品(Food for special medical purposes,FSMPs)能够为特定疾病或医学状况的人群提供专门摄取的营养或膳食需求,进而达到改善特殊人群患者营养不良状态、提高生存率、缩短住院时间和减少医疗费用等目的。概述了FSMPs的定义、功能和分类,介绍了近年来FSMPs的行业发展情况,并详细分析了国内外FSMPs的原料选择和配方设计,以及FSMPs在我国的注册申报、现场核查、产品检验与临床应用,为FSMPs未来的发展和市场应用提供参考借鉴。展开更多
文摘目的:探讨特殊医学用途配方食品(food for special medical purpose,FSMP)营养治疗新路径在痔疮患者术后快速康复中的有效性。方法:选取2017-10-01~2018-05-31在我院肛肠外科进行手术治疗的男性混合痔疮患者60例,随机分为观察组及对照组。观察组采用FSMP营养治疗新路径进行营养干预,对照组采用一般术后快速康复饮食治疗,观察两组患者住院时间、首次排便时间、术后前3d平均排便次数、主观满意度、出院时营养状况及营养风险发生率、术后不良反应发生率等。结果:观察组住院时间、首次排便时间、术后前3d平均排便次数、出院时营养风险发生率及术后不良反应发生率(术后疼痛、出血、感染、低血糖)均明显低于对照组;观察组患者出院时营养状况及主观满意度明显高于对照组,差异均具有统计学意义(P<0.05或P<0.01)。结论:FSMP营养治疗新路径能加快痔疮患者术后快速康复,应在临床广泛推广。
基金funded by the National Key Research and Development Program of China(2022YFF1100600/2022YFF1100604).
文摘Background and Objectives:Cancer patients at nutritional risk have a worse prognosis,but this can be im proved by nutritional support.Food for special medical purposes(FSMP),as a new form of nutritional support,needs to be further evaluated for its safety and efficacy in these patients.Our study elucidate the impact of FSMP on nutritional status and sarcopenia among nutritional risk cancer outpatients by assessing the NRS2002 score,exercise performance,muscle mass,and inflammatory factors pre-and postintervention.Methods and Study Design:We conducted a single-centre,double-blind,randomized controlled interventional study.Patients from the oncology clinic with nutritional risk were randomly allocated to the control group or the FSMP group and re ceived oral intervention for 8 weeks.The primary outcome was improvement in nutritional risk,while the sec ondary outcomes were improvements in sarcopenia prevalence and physical performance indicators.Other out comes included alterations in calf circumference,hsCRP,25(OH)VD3,Alb.etc.A linear mixed-effects model was used to compare the prepost-intervention changes in these results.Results:Thirty-six cancer patients were included,25 completed the study.The percentage of patients at nutritional risk after intervention in the FSMP group was significantly lower than the control group(Χ^(2)=4.186,p=0.041).The FSMP group demonstrated signif icant improvements in the TUG test,gait speed,grip strength,and upper-limb muscle mass.However,there was no significant improvement in the rate of sarcopenia.Moreover,calf circumference,hsCRP,25(OH)VD3,Alb exhibited no significant changes.Conclusions:FSMP can effectively improve the nutritional status,physical per formance and upper-limb muscle mass of cancer patients.
文摘本研究旨在探究巴氏杀菌和超高温瞬时杀菌(Ultra-high Temperature Instantaneous Sterilization,UHT)以及不同喷雾干燥进口温度对特殊医学用途配方食品(Foods for Special Medical Purposes,FSMPs)粉体特性的影响。通过润湿性、分散性、溶解性以及休止角、卡尔指数、豪斯那比,分别探究不同加工条件对粉体冲调性及流动性的影响;进一步通过水分含量及活度、粒径形态和表面成分揭示具体影响机制。结果显示:喷雾干燥进口温度为150℃时,UHT组样品的润湿时间相比于巴氏杀菌组显著缩短45.7%(P<0.05),水溶性指数显著升高13.8%(P<0.05),分散性指数显著降低16.1%(P<0.05)。喷雾干燥进口温度为170℃时,UHT组样品的卡尔指数和豪斯那比分别是巴氏杀菌组的59.3%和63.9%(P<0.05),水分含量是巴氏杀菌组81.4%(P<0.05),而平均粒径是巴氏杀菌组的1.94倍(P<0.05),扫描电镜下UHT组颗粒出现团聚现象,以及表面成分分析和激光共聚焦扫描显微镜结果显示UHT组表面脂质含量最高可达43.3%。随着喷雾干燥进口温度的升高,冲调性未呈现出显著变化趋势(P>0.05),而流动性呈现显著增加趋势(P<0.05)。综合来看,不同杀菌方式和喷雾干燥进口温度对特殊医学用途配方食品粉体冲调性和流动性、水分含量、粒径形态和表面脂质含量具有显著影响。本研究揭示了不同加工条件对于特殊医学用途配方食品粉体特性的影响及原因,为生产工艺的优化以及产品商业价值的提升提供理论指导。
文摘本文从医学营养学视角出发,聚焦糖尿病与慢性肾病(Chronic Kidney Disease, CKD)两类高发慢性病患者,深入探讨其专用预制菜(Specialized Prepared Meals for Patients with Specific Diseases, SPM-PSD)的发展路径。系统分析了糖尿病与CKD患者的核心营养需求及当前市场供给中的关键问题,明确了基于医学机制(如最新疾病营养指南)与工艺创新的研发思路,探讨了智能化技术应用与产业链协同的实践策略,梳理了政策支持对这一细分市场发展的推动作用。本文旨在为医疗机构将糖尿病、CKD患者的营养干预方案有效融入家庭餐桌提供理论支持与实践指导,助力实现国家“食养医防”全民健康战略目标。
文摘随着社会经济的发展和生活水平的提高,人们对营养与健康日渐重视。特殊医学用途配方食品(Food for special medical purposes,FSMPs)能够为特定疾病或医学状况的人群提供专门摄取的营养或膳食需求,进而达到改善特殊人群患者营养不良状态、提高生存率、缩短住院时间和减少医疗费用等目的。概述了FSMPs的定义、功能和分类,介绍了近年来FSMPs的行业发展情况,并详细分析了国内外FSMPs的原料选择和配方设计,以及FSMPs在我国的注册申报、现场核查、产品检验与临床应用,为FSMPs未来的发展和市场应用提供参考借鉴。
