<strong>Objective:</strong> To study the value of the filarial dance sign as a diagnostic sign in scrotal ultrasonography in human Bancroftian filariasis. <strong>Methods:</strong> We studied 3...<strong>Objective:</strong> To study the value of the filarial dance sign as a diagnostic sign in scrotal ultrasonography in human Bancroftian filariasis. <strong>Methods:</strong> We studied 3 patients with scrotal pain, with high-resolution ultrasonography (HRUS) of scrotum including power and color Doppler study. All patients underwent peripheral blood smear. <strong>Results:</strong> Multiple cystic spaces containing motile echogenic twisted tubular structures were observed in the 3 patients. Peripheral blood smears in the 3 patients confirmed the presence of microfilaria. Mild hydrocele in two patients. <strong>Conclusions:</strong> HRUS is a useful technique for diagnosing scrotal filariasis in symptomatic patients and is very useful in the follow-up treatment.展开更多
Investigations on the chemical constituents from the ethanol extract of the agarwood originating from Aquilaria filaria led to the isolation of 26 compounds by column chromatography,including silica gel,Sephadex LH-20...Investigations on the chemical constituents from the ethanol extract of the agarwood originating from Aquilaria filaria led to the isolation of 26 compounds by column chromatography,including silica gel,Sephadex LH-20,and semi-preparative high-performance liquid chromatography.Their structures were determined to beβ-sitostenone(1),24α-ethyl-cholestan-3α-ol(2),ergosta-4,6,8(14),22-tetraene-3-one(3),gypsogenin(4),hederagenin(5),17αH-trisnorhopanone(6),lupeol(7),friedelin(8),(-)-episyringaresinol(9),(-)-syringaresinol(10),5-hydroxy-7,4′-dimethoxyflavone(11),5,4’-dihydroxy-7,3′-dimethoxyflavone(12),2′-hydroxy-4,3′,6′,4′′-tetramethoxy-p-terphenyl(13),scopularide A(14),4-(4-hydroxyphenyl)butan-2-one(15),zingerone(16),coniferaldehyde(17),scopoletin(18),acetovanillon(19),isovanillin(20),vanillin(21),p-hydroxybenzaldehyde(22),p-hydroxybenzoic acid(23),protocatechuic acid(24),vanillic acid(25)and 4,5-dihydroxy-3-methoxybenzoic acid(26)by using spectroscopic techniques.All compounds were isolated from agarwood of A.filaria for the first time,and this was also the first report about the isolation of compounds 2,4,6,7,9,10,13-15,17-20,22,24 and 26 from agarwood and Aquilaria plants.展开更多
Objective:To understand the insecticide resistance status of Culex quinquefasciatus Say（Diptera: Culicidae）（Cx.Quinquefasciatus） to deltamethrin,cyfluthrin,permethrin,lambdacyhalothrin, DDT and malathion in filari...Objective:To understand the insecticide resistance status of Culex quinquefasciatus Say（Diptera: Culicidae）（Cx.Quinquefasciatus） to deltamethrin,cyfluthrin,permethrin,lambdacyhalothrin, DDT and malathion in filarial endemic areas of Uttar Pradesh,India.Methods:Insecticide susceptibility assays were performed on wild-caught adult female Cx.quinquefasciatus mosquitoes to deltamethrin（0.05%）,cyfluthrin（0.15%）,permethrin（0.75%）,lambdacyhalothrin （0.05%）,malathion（5.0%） and DDT（4.0%）,the discriminating doses recommended by the World Health Organisation（WHO）.Results:The data showed that Cx.quinquefasciatus is highly resistant to DDT and malathion;the mortality was 28.33%and 27.5%,respectively and incipient resistance to synthetic pyrethroids（deltamethrin,cyfluthrin,permethrin,and lambdacyhalothrin）, where mortality ranged from 95.83%in permethrin to 98.33%in cyfluthrin and lambdacyhalothrin. Knockdown times(KDT<sub>50</sub>) in response to synthetic pyrethroids varied significantly between different insecticides（P【0.01） from 31.480 min for permethrin to 21.650 for cyfluthrin. Conclusions:The results presents here provide the status report of the insecticide resistance/ susceptibility of Cx.quinquefasciatus in major filaria endemic areas of northern India.展开更多
Objective:To determine the prevalence,identify the species involved and assess possible risk factors of lungwonn infection in small ruminant slaughtered in abattoir of Mashhad in the northeast of Iran from October 201...Objective:To determine the prevalence,identify the species involved and assess possible risk factors of lungwonn infection in small ruminant slaughtered in abattoir of Mashhad in the northeast of Iran from October 2010 -August 2011.Methods:Faecal and post mortem examination were conducted on 350 and 2 500 animals,respectively.Results:The overall prevalence of lungwonn infection was 10.85%and 3.80%in coproscopic and post mortem examination respectively,and this difference was found to be significant.Higher prevalence of lungwonn infection was recorded in post mortem examination in sheep(4.1%) than in goats (0.5%)(P【0.05).The proportion of infection with Dictyocaulus filaria,Protostrongylus rufescens and mixed infection were 3.7%,0.1%and 0.2%in sheep while in goats,the infection was reported with Dictyocaulus filaria(0.5%) only.The seasonal dynamics of lungwonn infection showed that prevalence was highest in winter(7.8%) with a remarkable decline during the dry time(summer) (0.8%) which the difference was significant(P【0.001).The animals of less than one year old showed greater infection in post mortem examination than older animals significantly(P【0.001). Also,the infection rate between male and female animals showed significant difference(P【0.05) with prevalence rate of 4.6%and 2.0%,respectively.Conclusions:Due to its impact on production, emphasis should be given for the control and prevention of lungworm infection in this area.展开更多
文摘<strong>Objective:</strong> To study the value of the filarial dance sign as a diagnostic sign in scrotal ultrasonography in human Bancroftian filariasis. <strong>Methods:</strong> We studied 3 patients with scrotal pain, with high-resolution ultrasonography (HRUS) of scrotum including power and color Doppler study. All patients underwent peripheral blood smear. <strong>Results:</strong> Multiple cystic spaces containing motile echogenic twisted tubular structures were observed in the 3 patients. Peripheral blood smears in the 3 patients confirmed the presence of microfilaria. Mild hydrocele in two patients. <strong>Conclusions:</strong> HRUS is a useful technique for diagnosing scrotal filariasis in symptomatic patients and is very useful in the follow-up treatment.
基金National Key Research & Development Program of China (Grant No. 2018YFC1706400)National Natural Science Foundation of China (Grant No. 31870668)China Agriculture Research System (Grant No. CARS-21)。
文摘Investigations on the chemical constituents from the ethanol extract of the agarwood originating from Aquilaria filaria led to the isolation of 26 compounds by column chromatography,including silica gel,Sephadex LH-20,and semi-preparative high-performance liquid chromatography.Their structures were determined to beβ-sitostenone(1),24α-ethyl-cholestan-3α-ol(2),ergosta-4,6,8(14),22-tetraene-3-one(3),gypsogenin(4),hederagenin(5),17αH-trisnorhopanone(6),lupeol(7),friedelin(8),(-)-episyringaresinol(9),(-)-syringaresinol(10),5-hydroxy-7,4′-dimethoxyflavone(11),5,4’-dihydroxy-7,3′-dimethoxyflavone(12),2′-hydroxy-4,3′,6′,4′′-tetramethoxy-p-terphenyl(13),scopularide A(14),4-(4-hydroxyphenyl)butan-2-one(15),zingerone(16),coniferaldehyde(17),scopoletin(18),acetovanillon(19),isovanillin(20),vanillin(21),p-hydroxybenzaldehyde(22),p-hydroxybenzoic acid(23),protocatechuic acid(24),vanillic acid(25)and 4,5-dihydroxy-3-methoxybenzoic acid(26)by using spectroscopic techniques.All compounds were isolated from agarwood of A.filaria for the first time,and this was also the first report about the isolation of compounds 2,4,6,7,9,10,13-15,17-20,22,24 and 26 from agarwood and Aquilaria plants.
文摘Objective:To understand the insecticide resistance status of Culex quinquefasciatus Say（Diptera: Culicidae）（Cx.Quinquefasciatus） to deltamethrin,cyfluthrin,permethrin,lambdacyhalothrin, DDT and malathion in filarial endemic areas of Uttar Pradesh,India.Methods:Insecticide susceptibility assays were performed on wild-caught adult female Cx.quinquefasciatus mosquitoes to deltamethrin（0.05%）,cyfluthrin（0.15%）,permethrin（0.75%）,lambdacyhalothrin （0.05%）,malathion（5.0%） and DDT（4.0%）,the discriminating doses recommended by the World Health Organisation（WHO）.Results:The data showed that Cx.quinquefasciatus is highly resistant to DDT and malathion;the mortality was 28.33%and 27.5%,respectively and incipient resistance to synthetic pyrethroids（deltamethrin,cyfluthrin,permethrin,and lambdacyhalothrin）, where mortality ranged from 95.83%in permethrin to 98.33%in cyfluthrin and lambdacyhalothrin. Knockdown times(KDT<sub>50</sub>) in response to synthetic pyrethroids varied significantly between different insecticides（P【0.01） from 31.480 min for permethrin to 21.650 for cyfluthrin. Conclusions:The results presents here provide the status report of the insecticide resistance/ susceptibility of Cx.quinquefasciatus in major filaria endemic areas of northern India.
基金supported by the Ferdowsi University of Mashhad (Grant number 709)
文摘Objective:To determine the prevalence,identify the species involved and assess possible risk factors of lungwonn infection in small ruminant slaughtered in abattoir of Mashhad in the northeast of Iran from October 2010 -August 2011.Methods:Faecal and post mortem examination were conducted on 350 and 2 500 animals,respectively.Results:The overall prevalence of lungwonn infection was 10.85%and 3.80%in coproscopic and post mortem examination respectively,and this difference was found to be significant.Higher prevalence of lungwonn infection was recorded in post mortem examination in sheep(4.1%) than in goats (0.5%)(P【0.05).The proportion of infection with Dictyocaulus filaria,Protostrongylus rufescens and mixed infection were 3.7%,0.1%and 0.2%in sheep while in goats,the infection was reported with Dictyocaulus filaria(0.5%) only.The seasonal dynamics of lungwonn infection showed that prevalence was highest in winter(7.8%) with a remarkable decline during the dry time(summer) (0.8%) which the difference was significant(P【0.001).The animals of less than one year old showed greater infection in post mortem examination than older animals significantly(P【0.001). Also,the infection rate between male and female animals showed significant difference(P【0.05) with prevalence rate of 4.6%and 2.0%,respectively.Conclusions:Due to its impact on production, emphasis should be given for the control and prevention of lungworm infection in this area.
