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Fournier’s Gangrene: A Review of Fournier’s Gangrene Severity Index (FGSI) and Other Predictors of Mortality
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作者 Makama Baje Salihu Haruna Liman +3 位作者 Stephen Yusuf Aminu Umar Abraham Tunde Oladimeji Aremu Abdulrazak 《Open Journal of Urology》 2024年第7期391-399,共9页
Background: Fournier gangrene is an acute and rapidly progressive necrotizing fasciitis of the scrotum, perianal and perineal region of the body. It is a polymicrobial infection having an interplay of both anaerobic a... Background: Fournier gangrene is an acute and rapidly progressive necrotizing fasciitis of the scrotum, perianal and perineal region of the body. It is a polymicrobial infection having an interplay of both anaerobic and aerobic orgasms in a soup of microbial disaster. Fournier’s gangrene was also initially thought to be an idiopathic condition but a lot of risk factors have been associated now with this condition, both systemic risk factors and local. Systemic risk factors include diabetes mellitus, HIV/AIDS, cancers, chronic liver disease, chronic steroid use etc. The local risk factors include perineal injuries, watering can perineum, perianal abscess, chronic perineal itching etc. Purpose: The swiftly flourishing bacteria orgasms cause a similar disruptive event in the body of the patients both clinically and biochemically and these can be used to create a predictive score or index for patients in order to assess the disease severity and guide in the management and prognostication of this condition. Materials and Method: Urology ward record books, clinic record books and operating theater records were used to identify patients managed for Fournier gangrene in ATBUTH Bauchi. A retrospective study of the medical files of all the patients managed from January 2011 to January 2024 was done. Folders were retrieved and the medical records were reviewed. Results: Of the 50 patients reviewed, Male to female ratio is 24:1. The mean age is 56 years (2 weeks to 97 years). Mortality rate was 34%. There is a significant difference between delayed presentation/initial use of unorthodox treatment with mortality (p = 0.002). Of the 17 patients that died, 15 had FGSI > 9 and of the 33 patients that survived 29 had FGSI 9 is 88.2% while the mortality rate for those with FGSI Conclusion: knowledge of the predictors of its mortality is necessary in other to help stratify patients and ensure the best response by the caregivers. FGSI, delayed presentation/initial patronage of unorthodox care, and polymicrobial infection are important predictors of mortality in this condition. 展开更多
关键词 Fournier’s GANGRENE fgsi Risk Factors MORTALITY
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预后评分系统在Fournier坏疽诊治中的应用
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作者 郭宇文 朱一辰 +1 位作者 张健 张路加 《国际外科学杂志》 2016年第8期-,共5页
目的 比较两种预后评分系统在我国Fournier坏疽患者死亡风险预测中的适用情况.方法 回顾性分析15例Fournier坏疽患者的临床特点及治疗转归,将研究对象分为存活组(A组)和死亡组(B组),并应用Fournier坏疽严重程度指数(FGSI)和Uludag FGSI... 目的 比较两种预后评分系统在我国Fournier坏疽患者死亡风险预测中的适用情况.方法 回顾性分析15例Fournier坏疽患者的临床特点及治疗转归,将研究对象分为存活组(A组)和死亡组(B组),并应用Fournier坏疽严重程度指数(FGSI)和Uludag FGSI进行死亡风险评估,采用受试者工作特征曲线(ROC)进行评分表效果评估,并利用Z检验比较FGSI和UFGSI之间准确性的差异.结果 存活组(A组)11例,死亡组(B组)4例.平均年龄(P =0.024)及术前美国麻醉师协会(ASA)评分(P =0.04)B组均显著高于A组.A组患者接受的清创次数明显多于B组患者.FGSI评分A组低于B组[(1.6±0.9)vs (3.8±1.7),P<0.05].ROC曲线下面积(AUR) =0.886.UFGSI评分A组明显低于B组[(3.6±1.5)vs(6.0±2.2),P<0.05],ROC AUR=0.852.UFGSI和FGSI的AUC比较差异无统计学意义.结论 FGSI和UFGSI均可有效预测我国Fournier坏疽患者的死亡风险,并且两种评分系统差异无显著统计学意义,但适合我国患者的死亡评估阈值还需要进一步大样本研究重新确定. 展开更多
关键词 FOURNIER坏疽 预测评分系统 Fournier坏疽严重程度指数 Uludag fgsi 回顾性研究 死亡
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