Fasciolosis and hydatidosis are the world’s most common zoonotic major parasitic ailments of domesticated animals with financial and public health implications.A cross-sectional study was conducted on 384 randomly se...Fasciolosis and hydatidosis are the world’s most common zoonotic major parasitic ailments of domesticated animals with financial and public health implications.A cross-sectional study was conducted on 384 randomly selected cattle slaughtered at Wolaita Sodo municipal abattoir to estimate the prevalence and associated risk factors for co-infection of hydatidosis and fasciolosis using the ante-and postmortem examination techniques.Of the 384 examined cattle,4.17%were found to harbor co-infections of hydatidosis and fasciolosis.Similarly,the prevalence of concurrent fasciolosis and hydatidosis infections was 76.56%and 23.44%in local and crossbred animals,respectively.The current study took into account risk factors such as age,breed,origin,and body condition score;however,there is a statistically insignificant association between the risk factors and the prevalence of concurrent fasciolosis and hydatidosis infection.In this study,overall fasciolosis was recorded at a rate of 9.38%,with the highest prevalence of F.hepatica at 8.59%,followed by unidentified flukes at 4.17%and F.gigantica at 0.78%.Likewise,the single prevalence of hydatidosis was recorded at 10.94%.Of the 142 examined cysts,the liver alone harbors 54 cysts,and the lung alone harbors 88 cysts,with a total of 43 calcified,21 sterile,56 viable,9 nonviable,and 13 mixed cysts.The predicted yearly financial loss from organ condemnation was 15,436,142.00 ETB Birr.This study demonstrated that hydatidosis and fasciolosis are two relatively widespread parasite diseases of cattle in Ethiopia,causing significant economic loss attributable to organ rejection and indirect weight loss.Thus,awareness of the impact of the disease on the community could disrupt the parasite’s life cycle,and its economic significance was forwarded to other points.展开更多
Fasciolosis is one of the important diseases of livestock and has zoonotic importance.Fasciolosis can cause huge economic losses due to decrease in milk and meat production,decreased feed conversion ratio,and cost of ...Fasciolosis is one of the important diseases of livestock and has zoonotic importance.Fasciolosis can cause huge economic losses due to decrease in milk and meat production,decreased feed conversion ratio,and cost of treatment.Treatment and prophylaxis strategies for Fasciola infection are formed based on epidemiological data.The control of Fasciola infection can be attained by treating the animals with active anthelmintics.The use of different combinations of anthelmintics with a possible rotation is more effective against immature as well as adult flukes.Control of the intermediate host(snail)is vital for the reduction of fasciolosis.Due to the rapid growth of snails,the eradication is quite difficult in waterlogged and marshy areas.The use of different grazing methods and treatment of grazing areas can also help to control fasciolosis.A variety of antigens generated by Fasciola spp.have been shown to protect against liver fluke infection.The crude antigens,excretory/secretory,and refined antigens and their combination can be used as prophylactic treatment for the control of fasciolosis.The use of any of the single or combination of these methods can be very effective for the control of fasciolosis.展开更多
Objective:To evaluate the effect of enzymatic activity in the nervous tissue of snail Lymnaea acuminata(L.acuminata)by Bauhinia variegata(B.variegata)and Mimusops elengi(M.elengi)and their active molluscicidal compone...Objective:To evaluate the effect of enzymatic activity in the nervous tissue of snail Lymnaea acuminata(L.acuminata)by Bauhinia variegata(B.variegata)and Mimusops elengi(M.elengi)and their active molluscicidal components quercetin and saponin.Methods:Treatment of sublethal concentration(40%and 80%of 96-h LC_(50))in vivo of column-purified fraction of B.variegata leaf and M.elengi bark and their molluscicidal agents quercetin and saponin inhibit the acetylcholinesterase(AChE),acid and alkaline phosphatase(ACP and ALP)activities in the nervous tissue of L.acuminata.Results:AChE activity was more inhibited than ACP and ALP in snail exposed to column-purified fraction of M.elengi bark and saponin.Among all the treatments the highest inhibition in AChE activity(27.77%)was noted in snail L.acuminata exposed to 80%of 96-h LC_(50)of saponin at 96-h exposure period.Conclusions:It can be concluded from the present study that inhibition of AChE,ACP and ALP by B.variegata leaf(quercetin)and M.elengi bark(saponin)in snail L.acuminata could be the cause of snail mortality.展开更多
文摘Fasciolosis and hydatidosis are the world’s most common zoonotic major parasitic ailments of domesticated animals with financial and public health implications.A cross-sectional study was conducted on 384 randomly selected cattle slaughtered at Wolaita Sodo municipal abattoir to estimate the prevalence and associated risk factors for co-infection of hydatidosis and fasciolosis using the ante-and postmortem examination techniques.Of the 384 examined cattle,4.17%were found to harbor co-infections of hydatidosis and fasciolosis.Similarly,the prevalence of concurrent fasciolosis and hydatidosis infections was 76.56%and 23.44%in local and crossbred animals,respectively.The current study took into account risk factors such as age,breed,origin,and body condition score;however,there is a statistically insignificant association between the risk factors and the prevalence of concurrent fasciolosis and hydatidosis infection.In this study,overall fasciolosis was recorded at a rate of 9.38%,with the highest prevalence of F.hepatica at 8.59%,followed by unidentified flukes at 4.17%and F.gigantica at 0.78%.Likewise,the single prevalence of hydatidosis was recorded at 10.94%.Of the 142 examined cysts,the liver alone harbors 54 cysts,and the lung alone harbors 88 cysts,with a total of 43 calcified,21 sterile,56 viable,9 nonviable,and 13 mixed cysts.The predicted yearly financial loss from organ condemnation was 15,436,142.00 ETB Birr.This study demonstrated that hydatidosis and fasciolosis are two relatively widespread parasite diseases of cattle in Ethiopia,causing significant economic loss attributable to organ rejection and indirect weight loss.Thus,awareness of the impact of the disease on the community could disrupt the parasite’s life cycle,and its economic significance was forwarded to other points.
文摘Fasciolosis is one of the important diseases of livestock and has zoonotic importance.Fasciolosis can cause huge economic losses due to decrease in milk and meat production,decreased feed conversion ratio,and cost of treatment.Treatment and prophylaxis strategies for Fasciola infection are formed based on epidemiological data.The control of Fasciola infection can be attained by treating the animals with active anthelmintics.The use of different combinations of anthelmintics with a possible rotation is more effective against immature as well as adult flukes.Control of the intermediate host(snail)is vital for the reduction of fasciolosis.Due to the rapid growth of snails,the eradication is quite difficult in waterlogged and marshy areas.The use of different grazing methods and treatment of grazing areas can also help to control fasciolosis.A variety of antigens generated by Fasciola spp.have been shown to protect against liver fluke infection.The crude antigens,excretory/secretory,and refined antigens and their combination can be used as prophylactic treatment for the control of fasciolosis.The use of any of the single or combination of these methods can be very effective for the control of fasciolosis.
基金Supported by University Grants Commission(Grant No.F.No.39-590/2010).
文摘Objective:To evaluate the effect of enzymatic activity in the nervous tissue of snail Lymnaea acuminata(L.acuminata)by Bauhinia variegata(B.variegata)and Mimusops elengi(M.elengi)and their active molluscicidal components quercetin and saponin.Methods:Treatment of sublethal concentration(40%and 80%of 96-h LC_(50))in vivo of column-purified fraction of B.variegata leaf and M.elengi bark and their molluscicidal agents quercetin and saponin inhibit the acetylcholinesterase(AChE),acid and alkaline phosphatase(ACP and ALP)activities in the nervous tissue of L.acuminata.Results:AChE activity was more inhibited than ACP and ALP in snail exposed to column-purified fraction of M.elengi bark and saponin.Among all the treatments the highest inhibition in AChE activity(27.77%)was noted in snail L.acuminata exposed to 80%of 96-h LC_(50)of saponin at 96-h exposure period.Conclusions:It can be concluded from the present study that inhibition of AChE,ACP and ALP by B.variegata leaf(quercetin)and M.elengi bark(saponin)in snail L.acuminata could be the cause of snail mortality.
