The NaI and IF product rotational alignment of the reactions of Na,F+CH_3I has been theoretically studied in a LEPS PES.The product alignment versus the relative translational energy of the reactants has been obtained.
S.Lehrer and P.H.Rheinstein,“Alignment of Human Aquaporin 4 and fß-Amyloid Proteins May Indicate Involvement of fß-Amyloid in Brain Water Homeostasis and Prevention of Brain Edema,”Chronic Diseases and Tra...S.Lehrer and P.H.Rheinstein,“Alignment of Human Aquaporin 4 and fß-Amyloid Proteins May Indicate Involvement of fß-Amyloid in Brain Water Homeostasis and Prevention of Brain Edema,”Chronic Diseases and Translational Medicine 9(2023):177-181.https://doi.org/10.1002/cdt3.64.展开更多
Stewart platform(SP) is a promising choice for large component alignment, and interactive force measurements are a novel and significant approach for high-precision assemblies. The designed position and orientation(P&...Stewart platform(SP) is a promising choice for large component alignment, and interactive force measurements are a novel and significant approach for high-precision assemblies. The designed position and orientation(P&O) adjusting platform, based on an SP for force/torquedriven(F/T-driven) alignment, can dynamically measure interactive forces. This paper presents an analytical algorithm of measuring six-dimensional F/T based on the screw theory for accurate determination of external forces during alignment. Dynamic gravity deviations were taken into consideration and a compensation model was developed. The P&O number was optimized as well.Given the specific appearance of repeated six-dimensional F/T measurements, an approximate cone shape was used for spatial precision analysis. The magnitudes and directions of measured F/Ts can be evaluated by a set of standards, in terms of accuracy and repeatability. Experiments were also performed using a known applied load, and the proposed analytical algorithm was able to accurately predict the F/T. A comparison between precision analysis experiments with or without assembly fixtures was performed. Experimental results show that the measurement accuracy varies under different P&O sets and higher loads lead to poorer accuracy of dynamic gravity compensation. In addition, the preferable operation range has been discussed for high-precision assemblies with smaller deviations.展开更多
Increasing the accuracy of the nucleotide sequence alignment is an essential issue in genomics research.Although classic dynamic programming(DP)algorithms(e.g.,Smith–Waterman and Needleman–Wunsch)guarantee to produc...Increasing the accuracy of the nucleotide sequence alignment is an essential issue in genomics research.Although classic dynamic programming(DP)algorithms(e.g.,Smith–Waterman and Needleman–Wunsch)guarantee to produce the optimal result,their time complexity hinders the application of large-scale sequence alignment.Many optimization efforts that aim to accelerate the alignment process generally come from three perspectives:redesigning data structures[e.g.,diagonal or striped Single Instruction Multiple Data(SIMD)implementations],increasing the number of parallelisms in SIMD operations(e.g.,difference recurrence relation),or reducing search space(e.g.,banded DP).However,no methods combine all these three aspects to build an ultra-fast algorithm.In this study,we developed a Banded Striped Aligner(BSAlign)library that delivers accurate alignment results at an ultra-fast speed by knitting a series of novel methods together to take advantage of all of the aforementioned three perspectives with highlights such as active F-loop in striped vectorization and striped move in banded DP.We applied our new acceleration design on both regular and edit distance pairwise alignment.BSAlign achieved 2-fold speed-up than other SIMD-based implementations for regular pairwise alignment,and 1.5-fold to 4-fold speed-up in edit distance-based implementations for long reads.BSAlign is implemented in C programing language and is available at https://github.com/ruanjue/bsalign.展开更多
子午工程海南富克站甚高频(very high frequency,VHF)相干散射雷达位于我国海南省儋州市富克镇(109.1°E,19.5°N),隶属于中国科学院国家空间科学中心。雷达波束正交于电离层E和F层磁力线,其回波主要来自沿磁力线排列的电离层...子午工程海南富克站甚高频(very high frequency,VHF)相干散射雷达位于我国海南省儋州市富克镇(109.1°E,19.5°N),隶属于中国科学院国家空间科学中心。雷达波束正交于电离层E和F层磁力线,其回波主要来自沿磁力线排列的电离层场向不规则体的后向散射。2014-2019年甚高频相干散射雷达连续不间断地对海南地区电离层E层至F层高度范围内的等离子体不规则体进行探测,从原始探测数据同相、正交相(I、Q)信号中实时计算出回波强度并上传至子午工程数据中心。通过这一数据可以得到我国低纬地区(海南)电离层场向不规则体发生率随太阳活动、季节和地方时的变化,以及电离层不规则体发生情况的逐日变化和暴时响应特征。本数据集能够为我国电离层物理领域内相关的研究、工程项目、空间天气预报提供数据支撑。展开更多
文摘The NaI and IF product rotational alignment of the reactions of Na,F+CH_3I has been theoretically studied in a LEPS PES.The product alignment versus the relative translational energy of the reactants has been obtained.
文摘S.Lehrer and P.H.Rheinstein,“Alignment of Human Aquaporin 4 and fß-Amyloid Proteins May Indicate Involvement of fß-Amyloid in Brain Water Homeostasis and Prevention of Brain Edema,”Chronic Diseases and Translational Medicine 9(2023):177-181.https://doi.org/10.1002/cdt3.64.
基金co-supported by the National Defense Basic Scientific Research (No. A2120132007)the Fund of National Engineering and Research Center for Commercial Aircraft Manufacturing (No. SAMC14-JS-15-055)
文摘Stewart platform(SP) is a promising choice for large component alignment, and interactive force measurements are a novel and significant approach for high-precision assemblies. The designed position and orientation(P&O) adjusting platform, based on an SP for force/torquedriven(F/T-driven) alignment, can dynamically measure interactive forces. This paper presents an analytical algorithm of measuring six-dimensional F/T based on the screw theory for accurate determination of external forces during alignment. Dynamic gravity deviations were taken into consideration and a compensation model was developed. The P&O number was optimized as well.Given the specific appearance of repeated six-dimensional F/T measurements, an approximate cone shape was used for spatial precision analysis. The magnitudes and directions of measured F/Ts can be evaluated by a set of standards, in terms of accuracy and repeatability. Experiments were also performed using a known applied load, and the proposed analytical algorithm was able to accurately predict the F/T. A comparison between precision analysis experiments with or without assembly fixtures was performed. Experimental results show that the measurement accuracy varies under different P&O sets and higher loads lead to poorer accuracy of dynamic gravity compensation. In addition, the preferable operation range has been discussed for high-precision assemblies with smaller deviations.
基金supported by the National Natural Science Foundation of China(Grant Nos.31822029 and 32200517)the National Key R&D Project Program of China(Grant No.2019YFE0109600).
文摘Increasing the accuracy of the nucleotide sequence alignment is an essential issue in genomics research.Although classic dynamic programming(DP)algorithms(e.g.,Smith–Waterman and Needleman–Wunsch)guarantee to produce the optimal result,their time complexity hinders the application of large-scale sequence alignment.Many optimization efforts that aim to accelerate the alignment process generally come from three perspectives:redesigning data structures[e.g.,diagonal or striped Single Instruction Multiple Data(SIMD)implementations],increasing the number of parallelisms in SIMD operations(e.g.,difference recurrence relation),or reducing search space(e.g.,banded DP).However,no methods combine all these three aspects to build an ultra-fast algorithm.In this study,we developed a Banded Striped Aligner(BSAlign)library that delivers accurate alignment results at an ultra-fast speed by knitting a series of novel methods together to take advantage of all of the aforementioned three perspectives with highlights such as active F-loop in striped vectorization and striped move in banded DP.We applied our new acceleration design on both regular and edit distance pairwise alignment.BSAlign achieved 2-fold speed-up than other SIMD-based implementations for regular pairwise alignment,and 1.5-fold to 4-fold speed-up in edit distance-based implementations for long reads.BSAlign is implemented in C programing language and is available at https://github.com/ruanjue/bsalign.
文摘子午工程海南富克站甚高频(very high frequency,VHF)相干散射雷达位于我国海南省儋州市富克镇(109.1°E,19.5°N),隶属于中国科学院国家空间科学中心。雷达波束正交于电离层E和F层磁力线,其回波主要来自沿磁力线排列的电离层场向不规则体的后向散射。2014-2019年甚高频相干散射雷达连续不间断地对海南地区电离层E层至F层高度范围内的等离子体不规则体进行探测,从原始探测数据同相、正交相(I、Q)信号中实时计算出回波强度并上传至子午工程数据中心。通过这一数据可以得到我国低纬地区(海南)电离层场向不规则体发生率随太阳活动、季节和地方时的变化,以及电离层不规则体发生情况的逐日变化和暴时响应特征。本数据集能够为我国电离层物理领域内相关的研究、工程项目、空间天气预报提供数据支撑。
