The release of a new artificial intelligence(AI)model,ironically,evokes a biblical memory.What has transpired in the past few days echoes the biblical story of David versus Goliath,in which the massive and wellarmed G...The release of a new artificial intelligence(AI)model,ironically,evokes a biblical memory.What has transpired in the past few days echoes the biblical story of David versus Goliath,in which the massive and wellarmed Goliath is defeated by the comparatively puny David,who comes to the battle with only his staff and sling.展开更多
High pressure die casting(HPDC)AlSi10Mn Mg alloy castings are widely used in the automobile industry.Mg can optimize the mechanical properties of castings through heat treatment,while the release of thermal stress aro...High pressure die casting(HPDC)AlSi10Mn Mg alloy castings are widely used in the automobile industry.Mg can optimize the mechanical properties of castings through heat treatment,while the release of thermal stress arouses the deformation of large integrated die-castings.Herein,the development of non-heat treatment Al alloys is becoming the hot topic.In addition,HPDC contains externally solidified crystals(ESCs),which are detrimental to the mechanical properties of castings.To achieve high strength and toughness of non-heat treatment die-casting Al-Si alloy,we used AlSi9Mn alloy as matrix with the introduction of Zr,Ti,Nb,and Ce.Their influences on ESCs and mechanical properties were systematically investigated through three-dimensional reconstruction and thermodynamic simulation.Our results reveal that the addition of Ti increased ESCs'size and porosity,while the introduction of Nb refined ESCs and decreased porosity.Meanwhile,large-sized Al_3(Zr,Ti)phases formed and degraded the mechanical properties.Subsequent introduction of Ce resulted in the poisoning effect and reduced mechanical properties.展开更多
The paper presents experimental investigation results of crack pattern change in cement pastes caused by external sulfate attack(ESA).To visualize the formation and development of cracks in cement pastes under ESA,an ...The paper presents experimental investigation results of crack pattern change in cement pastes caused by external sulfate attack(ESA).To visualize the formation and development of cracks in cement pastes under ESA,an X-ray computed tomography(X-ray CT)was used,i e,the tomography system of Zeiss Xradia 510 versa.The results indicate that X-CT can monitor the development process and distribution characteristics of the internal cracks of cement pastes under ESA with attack time.In addition,the C3A content in the cement significantly affects the damage mode of cement paste specimens during sulfate erosion.The damage of ordinary Portland cement(OPC)pastes subjected to sulfate attack with high C3A content are severe,while the damage of sulfate resistant Portland cement(SRPC)pastes is much smaller than that of OPC pastes.Furthermore,a quadratic function describes the correlation between the crack volume fraction and development depth for two cement pastes immermed in sulfate solution.展开更多
Ultra-low emission of nitrogen oxide(NO_(x))is an irreversible trend for the development of waste-to-energy industry.But traditional approaches to remove NO_(x) face significant challenge s,such as low denitration eff...Ultra-low emission of nitrogen oxide(NO_(x))is an irreversible trend for the development of waste-to-energy industry.But traditional approaches to remove NO_(x) face significant challenge s,such as low denitration efficiency,complex denitration system,and high investment and operating cost.Here we put forward a novel polymer non-catalytic reduction(PNCR)technology that utilized a new type of polymer agent to remove NO_(x),and the proposed PNCR technology was applied to the existing waste-to-energy plant to test the denitration performance.The PNCR technology demonstrated excellent denitration performance with a NO_(x) emission concentration of<100 mg/Nm^(3) and high denitration efficiency of>75%at the temperature range of 800-900℃,which showed the application feasibility even on the complex and unstable industrial operating conditions.In addition,PNCR and hybrid polymer/selective non-catalytic reduction(PNCR/SNCR)technology possessed remarkable economic advantages including low investment fee and low operating cost of<10 CNY per ton of municipal solid waste(MSW)compared with selective catalytic reduction(SCR)technology.The excellent denitration performance of PNCR technology forebodes a broad industrial application prospect in the field of flue gas cleaning for waste-to-energy plants.展开更多
BACKGROUND Coronavirus disease 2019(COVID-19)is strongly associated with an increased risk of thrombotic events,including severe outcomes such as pulmonary embolism.Elevated D-dimer levels are a critical biomarker for...BACKGROUND Coronavirus disease 2019(COVID-19)is strongly associated with an increased risk of thrombotic events,including severe outcomes such as pulmonary embolism.Elevated D-dimer levels are a critical biomarker for assessing this risk.In Gabon,early implementation of anticoagulation therapy and D-dimer testing has been crucial in managing COVID-19.This study hypothesizes that elevated Ddimer levels are linked to increased COVID-19 severity.AIM To determine the impact of D-dimer levels on COVID-19 severity and their role in guiding clinical decisions.METHODS This retrospective study analyzed COVID-19 patients admitted to two hospitals in Gabon between March 2020 and December 2023.The study included patients with confirmed COVID-19 diagnoses and available D-dimer measurements at admission.Data on demographics,clinical outcomes,D-dimer levels,and healthcare costs were collected.COVID-19 severity was classified as non-severe(outpatients)or severe(inpatients).A multivariable logistic regression model was used to assess the relationship between D-dimer levels and disease severity,with adjusted odds ratios(OR)and 95%CI.RESULTS A total of 3004 patients were included,with a mean age of 50.17 years,and the majority were female(53.43%).Elevated D-dimer levels were found in 65.81%of patients,and 57.21%of these experienced severe COVID-19.Univariate analysis showed that patients with elevated D-dimer levels had 3.33 times higher odds of severe COVID-19(OR=3.33,95%CI:2.84-3.92,P<0.001),and this association remained significant in the multivariable analysis,adjusted for age,sex,and year of collection.The financial analysis revealed a substantial burden,particularly for uninsured patients.CONCLUSION D-dimer predicts COVID-19 severity and guides treatment,but the high cost of anticoagulant therapy highlights the need for policies ensuring affordable access in resource-limited settings like Gabon.展开更多
The new edition of the International Production Cost Comparison (IPCC) from ITMF has been published.The report benchmarks manufacturing costs for a range of textile products along the primary textile value chain,disag...The new edition of the International Production Cost Comparison (IPCC) from ITMF has been published.The report benchmarks manufacturing costs for a range of textile products along the primary textile value chain,disaggregated by key cost components at each production stage.展开更多
BACKGROUND Pain in the back or pelvis or fear of back pain may affect the timing or cocontraction of the core muscles.In both static and dynamic movements,the Sahrmann core stability test provides an assessment of cor...BACKGROUND Pain in the back or pelvis or fear of back pain may affect the timing or cocontraction of the core muscles.In both static and dynamic movements,the Sahrmann core stability test provides an assessment of core muscle activation and a person's ability to stabilize the lumbopelvic complex.Preparatory cues and images can be used to increase the activation of these muscles.To attain optimal movement patterns,it will be necessary to determine what cueing will give the most effective results for core stability.AIM To investigate the effects of external and internal cues on core muscle activation during the Sahrmann five-level core stability test.METHODS Total 68 participants(21.83±3.47 years)were randomly allocated to an external(n=35)or internal cue group(n=33).Participants performed the Sahrmann fivelevel core stability test without a cue as baseline and the five-level stability exercises with an internal or external cue.External cue group received a pressure biofeedback unit(PBU),and the internal cue group received an audio cue.A Delsys Trigno^(TM)surface electromyography unit was used for muscle activation from the rectus abdominis,external oblique,and transverse abdominis/internal oblique muscles.RESULTS Linear mixed effects model analysis showed that cueing had a significant effect on core muscle activation(P=0.001);however,there was no significant difference between cue types(internal or external)(P=0.130).CONCLUSION Both external and internal cueing have significant effects on core muscle activation during the Sahrmann five-level core stability test and the PBU does not create higher muscle activation than internal cueing.展开更多
The ease of accessing a virtually unlimited pool of resources makes Infrastructure as a Service (IaaS) clouds an ideal platform for running data-intensive workflow applications comprising hundreds of computational tas...The ease of accessing a virtually unlimited pool of resources makes Infrastructure as a Service (IaaS) clouds an ideal platform for running data-intensive workflow applications comprising hundreds of computational tasks. However, executing scientific workflows in IaaS cloud environments poses significant challenges due to conflicting objectives, such as minimizing execution time (makespan) and reducing resource utilization costs. This study responds to the increasing need for efficient and adaptable optimization solutions in dynamic and complex environments, which are critical for meeting the evolving demands of modern users and applications. This study presents an innovative multi-objective approach for scheduling scientific workflows in IaaS cloud environments. The proposed algorithm, MOS-MWMC, aims to minimize total execution time (makespan) and resource utilization costs by leveraging key features of virtual machine instances, such as a high number of cores and fast local SSD storage. By integrating realistic simulations based on the WRENCH framework, the method effectively dimensions the cloud infrastructure and optimizes resource usage. Experimental results highlight the superiority of MOS-MWMC compared to benchmark algorithms HEFT and Max-Min. The Pareto fronts obtained for the CyberShake, Epigenomics, and Montage workflows demonstrate closer proximity to the optimal front, confirming the algorithm’s ability to balance conflicting objectives. This study contributes to optimizing scientific workflows in complex environments by providing solutions tailored to specific user needs while minimizing costs and execution times.展开更多
COVID-19 placed increased pressure and urgency for effective cost management,resulting in unprecedented financial strains for hospitals.The pandemic also became a catalyst for accelerating digital transformation to im...COVID-19 placed increased pressure and urgency for effective cost management,resulting in unprecedented financial strains for hospitals.The pandemic also became a catalyst for accelerating digital transformation to improve operations and services in the healthcare industry.Morningdale Hospital is a large and reputable general hospital with a long history in the U.K.You are an intern in the Finance Department of the Hospital.The CEO has asked you to complete a patient-level cost analysis of endoscopic procedures in the Gastrointestinal Department.In your final report,you plan to include a SWOT analysis and a cost analysis using Activity-Based Costing accounting method.展开更多
The purpose of this article is to analyze the advantages and application paths of BIM5D technology in the cost control of completed houses.In the research phase,based on the reading of literature and the combination o...The purpose of this article is to analyze the advantages and application paths of BIM5D technology in the cost control of completed houses.In the research phase,based on the reading of literature and the combination of project materials,the advantages of BIM5D in the cost control project of completed houses are analyzed after introducing the cost control of completed houses and the connotation of BIM5D technology.Finally,this article starts from multiple perspectives,including BIM5D modeling,cost deviation analysis under dynamic cost control,etc.,and finally forms a relatively systematic and complete BIM cost control technology system.It is hoped that this article can provide technical reference value for China’s completed housing projects,promote the improvement of the project team’s cost control level,obtain considerable economic benefits based on completing project construction with quality and quantity,and enhance the competitiveness of enterprises.展开更多
Against the backdrop of the increasingly complex construction market environment,the whole-process cost management of agency-built projects faces issues such as cost overruns and insufficient management efficiency due...Against the backdrop of the increasingly complex construction market environment,the whole-process cost management of agency-built projects faces issues such as cost overruns and insufficient management efficiency due to the numerous stages and high technical requirements involved.This paper focuses on the key stages of whole-process cost management in agency-built projects,including project initiation,design,construction,and completion.It proposes strategies to optimize the cost management process and enhance management efficiency,providing theoretical support and practical guidance for the whole-process cost management under the agency-built model.展开更多
The commercialization of perovskite solar cells(PSCs)has garnered worldwide attention and many efforts were devoted on the improvement of efficiency and stability.Here,we estimated the cost effectivities of PSCs based...The commercialization of perovskite solar cells(PSCs)has garnered worldwide attention and many efforts were devoted on the improvement of efficiency and stability.Here,we estimated the cost effectivities of PSCs based on the current industrial condition.Through the analysis of current process,the manufacturing cost and the levelized cost of electricity(LCOE)of PSCs is estimated as 0.57$W^(−1) and 18-22 US cents(kWh)^(−1),respectively,and we demonstrate the materials cost shares 70%of the total cost.Sensitivity analysis indicates that the improvement of efficiency,yield and decrease in materials cost significantly reduce the cost of the modules.Analysis of the module cost and LCOE indicates that the PSCs have the potential to outperform the silicon solar cells in the condition of over 25%efficiency and 25-year lifetime in future.To achieve this target,it is essential to further refine the fabrication processes of each layer in the module,develop stable inorganic transport materials,and precisely control material formation and processing at the microscale and nanoscale to enhance charge transport.展开更多
This study explores whether the current external quality assessment(EQA)level and acceptable bias for basic semen analysis in China are clinically useful.We collected data of semen EQA from Andrology laboratories in t...This study explores whether the current external quality assessment(EQA)level and acceptable bias for basic semen analysis in China are clinically useful.We collected data of semen EQA from Andrology laboratories in the Hunan Province(China)in 2022 and searched for data in the published literature from January2000 to December 2023 in China.On the basis of these data,we analyzed the coefficients of variation and acceptable biases of different quality control materials for basic semen analysis through robust statistics.We compared these findings with quality specifications based on biological variation from optimal,desirable,and minimum levels of bias to seek a unified and more suitable semen EQAbias evaluation standard for China's national conditions.Different sources of semen quality control material exhibited considerable variation in acceptable biases among laboratories,ranging from 8.2%to 56.9%.A total of 50.0% of the laboratories met the minimum quality specifications for progressive motility(PR),whereas 100.0%and 75.0%of laboratories met only the minimum quality specifications for sperm concentration and total motility(nonprogressive[NP]+PR),respectively.The Z value for sperm concentration and PR+NP was equivalent to the desirable performance specification,whereas the Z value for PR was equivalent only to the minimum performance specification.This study highlights the feasibility of operating external quality assessment schemes for basic semen analysis using quality specifications based on biological variation.These specifications should be unified among external quality control(EQC)centers based on biological variation.展开更多
Dear Editor,We aimed to describe the management of the intraoperative injury of the right external iliac artery that occurred during robot-assisted right nephroureterectomy with bladder cuff excision.Surgery was sched...Dear Editor,We aimed to describe the management of the intraoperative injury of the right external iliac artery that occurred during robot-assisted right nephroureterectomy with bladder cuff excision.Surgery was scheduled for suspected urothelial carcinoma of the distal ureter in a 60-year-old woman.The patient involved in the present research signed a dedicated form to consent to the publication of images and/or information about her.Past medical history included Brugada syndrome diagnosed in 2015,and hypercholesterolemia.Past surgical history included one cesarean section only.Family history included ovarian cancer(sister),colorectal cancer(mother),and kidney cancer(father).展开更多
Obesity is a common chronic metabolic disease affecting populations in multiple countries and regions worldwide.Traditional Chinese medicine(TCM)external treatments have garnered increasing attention due to their uniq...Obesity is a common chronic metabolic disease affecting populations in multiple countries and regions worldwide.Traditional Chinese medicine(TCM)external treatments have garnered increasing attention due to their unique therapeutic advantages,such as simplicity of operation,proven efficacy,and minimal side effects.In recent years,research on the application of TCM external treatments in obesity treatment has deepened,involving various methods such as acupuncture,tuina(massage),acupoint catgut embedding,and acupoint herbal patching.This article reviews relevant studies to provide new insights for enhancing clinical efficacy and safety.展开更多
In clinical environments,the prolonged utilization of polarization equipment can result in theaccumulation of errors over extended periods.The absence of expeditious calibration techniques in clinical practice present...In clinical environments,the prolonged utilization of polarization equipment can result in theaccumulation of errors over extended periods.The absence of expeditious calibration techniques in clinical practice presents a significant obstacle in preserving the precision and dependability of these instruments.To address this challenge,we propose an innovative research study that presents a comprebersive calibration system specifically designed for the calibration of the backscattering Muellet matrix measurement system,enabling swift online calibration acroes various scenarios.This system employs an external calibration framework for rmal-time adjust-ment of the polarizer's initial angle,oversecing the rotation of PSG and PSA motors through position measurement and control procedures,with light intensity monitored by a camera.By incorporating moment um concepts and the Adam optimization algorithm,we enhance conver-gence speed,mitigate noise,and improve calibration accuracy.Experimental results showcase the exceptional precision,speed,and robustness of oрroposed method,achieving high acсuracy and minimal error,thereby offering a promising solution for maintaining the reliabilit y of polarization equipment in clinical settings.展开更多
Background:Radiation cystitis is a well-known complication resulting from radiotherapy for pelvic malignancies.It remains a challenging condition to treat and is associated with significant morbidity for patients.We a...Background:Radiation cystitis is a well-known complication resulting from radiotherapy for pelvic malignancies.It remains a challenging condition to treat and is associated with significant morbidity for patients.We aimed to establish the economic cost burden of presentations and investigations associated with radiation cystitis over a two-year period to a tertiary referral hospital in Ireland.Materials and Methods:A retrospective review of patient charts was performed for radiation cystitisrelated presentations and investigations over 24 months.Costs were estimated in consultation with the hospital finance department and using Health Service Executive data on diagnostic-related groups and average inpatient bed day costs.Results:A total of 56 individual patients were identified over 2 years.91%male,9%female.The mean age was 72 years.Twenty-three patients(41%)required inpatient care.Radiation cystitis accounted for 621 inpatient bed days.Median length of stay was 7.5 days.The inpatient care cost was approximately e545,238(801,908 Canadian dollars(CA$))over 2 years.Conclusion:Radiation cystitis accounts for a significant amount of inpatient bed days.A conservative estimate of the overall cost burden for inpatient care and outpatient investigations exceeds e280,000(CA$411,810)per year.展开更多
The metamaterial based on external meshing gears(MEG)is designed based on the principle of external meshing gear transmission.Based on the meshing transmission principle of external meshing gears and planetary gear tr...The metamaterial based on external meshing gears(MEG)is designed based on the principle of external meshing gear transmission.Based on the meshing transmission principle of external meshing gears and planetary gear trains,the internal and external gear rings are designed.Based on the internal and external gear rings,the metamaterial based on inner and outer planetary gear trains(MIP)is designed to study the shear modulus,Young's modulus,and amplitude-frequency characteristics of the metamaterial based on gears at different angles.The effects of the number of planetary gears on the physical characteristics of the MIP are studied.The results show that the MEG can be continuously adjusted by adjusting the shear modulus and Young's modulus due to its meshing characteristics.With the same number of gears,the adjustment range of the MIP is larger than the adjustment range of the MEG.When the number of planetary gears increases,the adjustment range of the MIP decreases.Moreover,when the metamaterial based on gears rotates,the harmonic response changes with the change of the angle.展开更多
文摘The release of a new artificial intelligence(AI)model,ironically,evokes a biblical memory.What has transpired in the past few days echoes the biblical story of David versus Goliath,in which the massive and wellarmed Goliath is defeated by the comparatively puny David,who comes to the battle with only his staff and sling.
基金financially supported by the National Natural Science Foundation of China(Nos.52175284 and 52474396)the National Key Research and Development Program of China(No.2022YFB3404201)。
文摘High pressure die casting(HPDC)AlSi10Mn Mg alloy castings are widely used in the automobile industry.Mg can optimize the mechanical properties of castings through heat treatment,while the release of thermal stress arouses the deformation of large integrated die-castings.Herein,the development of non-heat treatment Al alloys is becoming the hot topic.In addition,HPDC contains externally solidified crystals(ESCs),which are detrimental to the mechanical properties of castings.To achieve high strength and toughness of non-heat treatment die-casting Al-Si alloy,we used AlSi9Mn alloy as matrix with the introduction of Zr,Ti,Nb,and Ce.Their influences on ESCs and mechanical properties were systematically investigated through three-dimensional reconstruction and thermodynamic simulation.Our results reveal that the addition of Ti increased ESCs'size and porosity,while the introduction of Nb refined ESCs and decreased porosity.Meanwhile,large-sized Al_3(Zr,Ti)phases formed and degraded the mechanical properties.Subsequent introduction of Ce resulted in the poisoning effect and reduced mechanical properties.
基金Funded by Chinese National Natural Science Foundation of China(No.U2006224)。
文摘The paper presents experimental investigation results of crack pattern change in cement pastes caused by external sulfate attack(ESA).To visualize the formation and development of cracks in cement pastes under ESA,an X-ray computed tomography(X-ray CT)was used,i e,the tomography system of Zeiss Xradia 510 versa.The results indicate that X-CT can monitor the development process and distribution characteristics of the internal cracks of cement pastes under ESA with attack time.In addition,the C3A content in the cement significantly affects the damage mode of cement paste specimens during sulfate erosion.The damage of ordinary Portland cement(OPC)pastes subjected to sulfate attack with high C3A content are severe,while the damage of sulfate resistant Portland cement(SRPC)pastes is much smaller than that of OPC pastes.Furthermore,a quadratic function describes the correlation between the crack volume fraction and development depth for two cement pastes immermed in sulfate solution.
基金supported by the National Natural Science Foundation of China(No.92367107)。
文摘Ultra-low emission of nitrogen oxide(NO_(x))is an irreversible trend for the development of waste-to-energy industry.But traditional approaches to remove NO_(x) face significant challenge s,such as low denitration efficiency,complex denitration system,and high investment and operating cost.Here we put forward a novel polymer non-catalytic reduction(PNCR)technology that utilized a new type of polymer agent to remove NO_(x),and the proposed PNCR technology was applied to the existing waste-to-energy plant to test the denitration performance.The PNCR technology demonstrated excellent denitration performance with a NO_(x) emission concentration of<100 mg/Nm^(3) and high denitration efficiency of>75%at the temperature range of 800-900℃,which showed the application feasibility even on the complex and unstable industrial operating conditions.In addition,PNCR and hybrid polymer/selective non-catalytic reduction(PNCR/SNCR)technology possessed remarkable economic advantages including low investment fee and low operating cost of<10 CNY per ton of municipal solid waste(MSW)compared with selective catalytic reduction(SCR)technology.The excellent denitration performance of PNCR technology forebodes a broad industrial application prospect in the field of flue gas cleaning for waste-to-energy plants.
文摘BACKGROUND Coronavirus disease 2019(COVID-19)is strongly associated with an increased risk of thrombotic events,including severe outcomes such as pulmonary embolism.Elevated D-dimer levels are a critical biomarker for assessing this risk.In Gabon,early implementation of anticoagulation therapy and D-dimer testing has been crucial in managing COVID-19.This study hypothesizes that elevated Ddimer levels are linked to increased COVID-19 severity.AIM To determine the impact of D-dimer levels on COVID-19 severity and their role in guiding clinical decisions.METHODS This retrospective study analyzed COVID-19 patients admitted to two hospitals in Gabon between March 2020 and December 2023.The study included patients with confirmed COVID-19 diagnoses and available D-dimer measurements at admission.Data on demographics,clinical outcomes,D-dimer levels,and healthcare costs were collected.COVID-19 severity was classified as non-severe(outpatients)or severe(inpatients).A multivariable logistic regression model was used to assess the relationship between D-dimer levels and disease severity,with adjusted odds ratios(OR)and 95%CI.RESULTS A total of 3004 patients were included,with a mean age of 50.17 years,and the majority were female(53.43%).Elevated D-dimer levels were found in 65.81%of patients,and 57.21%of these experienced severe COVID-19.Univariate analysis showed that patients with elevated D-dimer levels had 3.33 times higher odds of severe COVID-19(OR=3.33,95%CI:2.84-3.92,P<0.001),and this association remained significant in the multivariable analysis,adjusted for age,sex,and year of collection.The financial analysis revealed a substantial burden,particularly for uninsured patients.CONCLUSION D-dimer predicts COVID-19 severity and guides treatment,but the high cost of anticoagulant therapy highlights the need for policies ensuring affordable access in resource-limited settings like Gabon.
文摘The new edition of the International Production Cost Comparison (IPCC) from ITMF has been published.The report benchmarks manufacturing costs for a range of textile products along the primary textile value chain,disaggregated by key cost components at each production stage.
文摘BACKGROUND Pain in the back or pelvis or fear of back pain may affect the timing or cocontraction of the core muscles.In both static and dynamic movements,the Sahrmann core stability test provides an assessment of core muscle activation and a person's ability to stabilize the lumbopelvic complex.Preparatory cues and images can be used to increase the activation of these muscles.To attain optimal movement patterns,it will be necessary to determine what cueing will give the most effective results for core stability.AIM To investigate the effects of external and internal cues on core muscle activation during the Sahrmann five-level core stability test.METHODS Total 68 participants(21.83±3.47 years)were randomly allocated to an external(n=35)or internal cue group(n=33).Participants performed the Sahrmann fivelevel core stability test without a cue as baseline and the five-level stability exercises with an internal or external cue.External cue group received a pressure biofeedback unit(PBU),and the internal cue group received an audio cue.A Delsys Trigno^(TM)surface electromyography unit was used for muscle activation from the rectus abdominis,external oblique,and transverse abdominis/internal oblique muscles.RESULTS Linear mixed effects model analysis showed that cueing had a significant effect on core muscle activation(P=0.001);however,there was no significant difference between cue types(internal or external)(P=0.130).CONCLUSION Both external and internal cueing have significant effects on core muscle activation during the Sahrmann five-level core stability test and the PBU does not create higher muscle activation than internal cueing.
文摘The ease of accessing a virtually unlimited pool of resources makes Infrastructure as a Service (IaaS) clouds an ideal platform for running data-intensive workflow applications comprising hundreds of computational tasks. However, executing scientific workflows in IaaS cloud environments poses significant challenges due to conflicting objectives, such as minimizing execution time (makespan) and reducing resource utilization costs. This study responds to the increasing need for efficient and adaptable optimization solutions in dynamic and complex environments, which are critical for meeting the evolving demands of modern users and applications. This study presents an innovative multi-objective approach for scheduling scientific workflows in IaaS cloud environments. The proposed algorithm, MOS-MWMC, aims to minimize total execution time (makespan) and resource utilization costs by leveraging key features of virtual machine instances, such as a high number of cores and fast local SSD storage. By integrating realistic simulations based on the WRENCH framework, the method effectively dimensions the cloud infrastructure and optimizes resource usage. Experimental results highlight the superiority of MOS-MWMC compared to benchmark algorithms HEFT and Max-Min. The Pareto fronts obtained for the CyberShake, Epigenomics, and Montage workflows demonstrate closer proximity to the optimal front, confirming the algorithm’s ability to balance conflicting objectives. This study contributes to optimizing scientific workflows in complex environments by providing solutions tailored to specific user needs while minimizing costs and execution times.
文摘COVID-19 placed increased pressure and urgency for effective cost management,resulting in unprecedented financial strains for hospitals.The pandemic also became a catalyst for accelerating digital transformation to improve operations and services in the healthcare industry.Morningdale Hospital is a large and reputable general hospital with a long history in the U.K.You are an intern in the Finance Department of the Hospital.The CEO has asked you to complete a patient-level cost analysis of endoscopic procedures in the Gastrointestinal Department.In your final report,you plan to include a SWOT analysis and a cost analysis using Activity-Based Costing accounting method.
文摘The purpose of this article is to analyze the advantages and application paths of BIM5D technology in the cost control of completed houses.In the research phase,based on the reading of literature and the combination of project materials,the advantages of BIM5D in the cost control project of completed houses are analyzed after introducing the cost control of completed houses and the connotation of BIM5D technology.Finally,this article starts from multiple perspectives,including BIM5D modeling,cost deviation analysis under dynamic cost control,etc.,and finally forms a relatively systematic and complete BIM cost control technology system.It is hoped that this article can provide technical reference value for China’s completed housing projects,promote the improvement of the project team’s cost control level,obtain considerable economic benefits based on completing project construction with quality and quantity,and enhance the competitiveness of enterprises.
文摘Against the backdrop of the increasingly complex construction market environment,the whole-process cost management of agency-built projects faces issues such as cost overruns and insufficient management efficiency due to the numerous stages and high technical requirements involved.This paper focuses on the key stages of whole-process cost management in agency-built projects,including project initiation,design,construction,and completion.It proposes strategies to optimize the cost management process and enhance management efficiency,providing theoretical support and practical guidance for the whole-process cost management under the agency-built model.
基金National Key R&D Program of China(No.2021YFB3800068)the National Natural Science Foundation of China(No.U21A20171).
文摘The commercialization of perovskite solar cells(PSCs)has garnered worldwide attention and many efforts were devoted on the improvement of efficiency and stability.Here,we estimated the cost effectivities of PSCs based on the current industrial condition.Through the analysis of current process,the manufacturing cost and the levelized cost of electricity(LCOE)of PSCs is estimated as 0.57$W^(−1) and 18-22 US cents(kWh)^(−1),respectively,and we demonstrate the materials cost shares 70%of the total cost.Sensitivity analysis indicates that the improvement of efficiency,yield and decrease in materials cost significantly reduce the cost of the modules.Analysis of the module cost and LCOE indicates that the PSCs have the potential to outperform the silicon solar cells in the condition of over 25%efficiency and 25-year lifetime in future.To achieve this target,it is essential to further refine the fabrication processes of each layer in the module,develop stable inorganic transport materials,and precisely control material formation and processing at the microscale and nanoscale to enhance charge transport.
基金supported by the Hunan Province Municipal Natural Science Foundation(2022JJ30018)the Hunan Province Health Commission Science Foundation(B202301037899)to WNL。
文摘This study explores whether the current external quality assessment(EQA)level and acceptable bias for basic semen analysis in China are clinically useful.We collected data of semen EQA from Andrology laboratories in the Hunan Province(China)in 2022 and searched for data in the published literature from January2000 to December 2023 in China.On the basis of these data,we analyzed the coefficients of variation and acceptable biases of different quality control materials for basic semen analysis through robust statistics.We compared these findings with quality specifications based on biological variation from optimal,desirable,and minimum levels of bias to seek a unified and more suitable semen EQAbias evaluation standard for China's national conditions.Different sources of semen quality control material exhibited considerable variation in acceptable biases among laboratories,ranging from 8.2%to 56.9%.A total of 50.0% of the laboratories met the minimum quality specifications for progressive motility(PR),whereas 100.0%and 75.0%of laboratories met only the minimum quality specifications for sperm concentration and total motility(nonprogressive[NP]+PR),respectively.The Z value for sperm concentration and PR+NP was equivalent to the desirable performance specification,whereas the Z value for PR was equivalent only to the minimum performance specification.This study highlights the feasibility of operating external quality assessment schemes for basic semen analysis using quality specifications based on biological variation.These specifications should be unified among external quality control(EQC)centers based on biological variation.
文摘Dear Editor,We aimed to describe the management of the intraoperative injury of the right external iliac artery that occurred during robot-assisted right nephroureterectomy with bladder cuff excision.Surgery was scheduled for suspected urothelial carcinoma of the distal ureter in a 60-year-old woman.The patient involved in the present research signed a dedicated form to consent to the publication of images and/or information about her.Past medical history included Brugada syndrome diagnosed in 2015,and hypercholesterolemia.Past surgical history included one cesarean section only.Family history included ovarian cancer(sister),colorectal cancer(mother),and kidney cancer(father).
基金Supported by National Natural Science Foundation of China(82174525)Natural Science Foundation of Jilin Province(YDZJ202301ZYTS469)+1 种基金Science and Technology Research Project of Jilin Provincial Department of Education in 2022(JJKH20230966KJ)2023 Jilin College Student Innovation and Entrepreneurship Training Project(S202310199043).
文摘Obesity is a common chronic metabolic disease affecting populations in multiple countries and regions worldwide.Traditional Chinese medicine(TCM)external treatments have garnered increasing attention due to their unique therapeutic advantages,such as simplicity of operation,proven efficacy,and minimal side effects.In recent years,research on the application of TCM external treatments in obesity treatment has deepened,involving various methods such as acupuncture,tuina(massage),acupoint catgut embedding,and acupoint herbal patching.This article reviews relevant studies to provide new insights for enhancing clinical efficacy and safety.
基金the Knowledge Innovation Program of Basic Re-search Projects of Shenzhen for their support under Grant No.JCYJ20200109142805928the funding provided by the Basic and Applied Basic Research Foundation of Guangdong Provinæunder Grant No.2021A1515220113partially supported by the Guangzhou Municipal Science and Technology Project under Grant 202102010421.
文摘In clinical environments,the prolonged utilization of polarization equipment can result in theaccumulation of errors over extended periods.The absence of expeditious calibration techniques in clinical practice presents a significant obstacle in preserving the precision and dependability of these instruments.To address this challenge,we propose an innovative research study that presents a comprebersive calibration system specifically designed for the calibration of the backscattering Muellet matrix measurement system,enabling swift online calibration acroes various scenarios.This system employs an external calibration framework for rmal-time adjust-ment of the polarizer's initial angle,oversecing the rotation of PSG and PSA motors through position measurement and control procedures,with light intensity monitored by a camera.By incorporating moment um concepts and the Adam optimization algorithm,we enhance conver-gence speed,mitigate noise,and improve calibration accuracy.Experimental results showcase the exceptional precision,speed,and robustness of oрroposed method,achieving high acсuracy and minimal error,thereby offering a promising solution for maintaining the reliabilit y of polarization equipment in clinical settings.
文摘Background:Radiation cystitis is a well-known complication resulting from radiotherapy for pelvic malignancies.It remains a challenging condition to treat and is associated with significant morbidity for patients.We aimed to establish the economic cost burden of presentations and investigations associated with radiation cystitis over a two-year period to a tertiary referral hospital in Ireland.Materials and Methods:A retrospective review of patient charts was performed for radiation cystitisrelated presentations and investigations over 24 months.Costs were estimated in consultation with the hospital finance department and using Health Service Executive data on diagnostic-related groups and average inpatient bed day costs.Results:A total of 56 individual patients were identified over 2 years.91%male,9%female.The mean age was 72 years.Twenty-three patients(41%)required inpatient care.Radiation cystitis accounted for 621 inpatient bed days.Median length of stay was 7.5 days.The inpatient care cost was approximately e545,238(801,908 Canadian dollars(CA$))over 2 years.Conclusion:Radiation cystitis accounts for a significant amount of inpatient bed days.A conservative estimate of the overall cost burden for inpatient care and outpatient investigations exceeds e280,000(CA$411,810)per year.
基金supported by the Guangxi Science and Technology Major Program of China(Nos.AA23073019 and AA24263074)the National Natural Science Foundation of China(No.52265004)+7 种基金the Guangxi Natural Science Fund for Distinguished Young Scholars of China(No.2024JJG160014)the Innovation Project of Guangxi Graduate Education of China(No.YCSW2024119)the Open Fund of State Key Laboratory of Intelligent Manufacturing Equipment and Technology of China(No.IMETKF2025021)the Open Research Fund of State Key Laboratory of Precision Manufacturing for Extreme Service Performance-Central South University of China(No.Kfkt2023-06)the Open Fund of High-end Basic Component Innovation Station of China(No.KY01080030124001)the Open Fund for Academician Mao Ming's Workstation of China(No.XSJSFW-QNKXJ-202404-007)the Technology Innovation Platform Project of China Aviation Engine Group Corporation(No.CXPT-2023-044)the Open Fund for Innovation Workstation in the National Defense Science and Technology Innovation Special Zone(Xi'an Jiaotong University).
文摘The metamaterial based on external meshing gears(MEG)is designed based on the principle of external meshing gear transmission.Based on the meshing transmission principle of external meshing gears and planetary gear trains,the internal and external gear rings are designed.Based on the internal and external gear rings,the metamaterial based on inner and outer planetary gear trains(MIP)is designed to study the shear modulus,Young's modulus,and amplitude-frequency characteristics of the metamaterial based on gears at different angles.The effects of the number of planetary gears on the physical characteristics of the MIP are studied.The results show that the MEG can be continuously adjusted by adjusting the shear modulus and Young's modulus due to its meshing characteristics.With the same number of gears,the adjustment range of the MIP is larger than the adjustment range of the MEG.When the number of planetary gears increases,the adjustment range of the MIP decreases.Moreover,when the metamaterial based on gears rotates,the harmonic response changes with the change of the angle.
