ZTE Corporation demonstrated video call, video streaming, and ftp services based on LTE-A Coordinated Multipoint （CoMP） technology at ＂Mobile World Congress 2011＂ in Barcelona, Spain. This makes ZTE the first and ...ZTE Corporation demonstrated video call, video streaming, and ftp services based on LTE-A Coordinated Multipoint （CoMP） technology at ＂Mobile World Congress 2011＂ in Barcelona, Spain. This makes ZTE the first and only telecoms vendor in the world to demonstrate LTE-A CoMP-based services.展开更多
Foreign Investors Able to Establish Foreign-exclusively Exhibition Corporations In Feb, Ministry of Commerce issued its 1st decree on temporary regulation for foreign-investing corporations; the regulation allows fore...Foreign Investors Able to Establish Foreign-exclusively Exhibition Corporations In Feb, Ministry of Commerce issued its 1st decree on temporary regulation for foreign-investing corporations; the regulation allows foreign investors to set up foreign-investing convention & exhibition corporations exclusively or through cooperation with other Chinese corporations, enterprises or organizations. With legal protection on their regulatory management and legal rights, these foreign-investing corporations are in the charge of Department of Foreign Investment Administration, Ministry of Commerce.展开更多
Objective: The inexistence of publications on hemoglobin values in the first six months of life gave us the objective of describing these values, month by month in healthy, iron sufficient exclusively breastfed infant...Objective: The inexistence of publications on hemoglobin values in the first six months of life gave us the objective of describing these values, month by month in healthy, iron sufficient exclusively breastfed infants. Methods: This was a cross-sectional descriptive study in 306 infants stratified according to age from one to six months, full-term births, weighing ≥2500 g, without intercurrences at birth, serum ferritin levels ≥10 ng/mL, followed by the public health service encouraging and supporting exclusive breastfeeding. An automated counter was used for measuring hemoglobin, and serum ferritin was determined using immunoenzymatic method. Student’s t-test was used to analyze differences between means, and Mann-Whitney test when distribution was non-normal. Level of statistical significance was p 0.05. Results: The hemoglobin values, according to gender, did not differ statistically in the different months;the results are presented without sample division according to gender. Hemoglobin means and standard deviations in g/dL were: 11.7(±1.6), 10.7(±1.5), 10.8(±1.3), 11.6(±1.5), 11.7(±1.7), and 11.8(±1.6), from the first to sixth month respectively. Conclusion: The hemoglobin values obtained in all the first six months of life, based on a healthy, exclusively breastfed infant population, may contribute to the reassessment of reference levels for the diagnosis of anemia in the studied age range.展开更多
Programmed cell death(PCD)is an essential process for development,and shows conserved cytological features in both plants and animals.Caspases are well-known critical components of the PCD machinery in animals.However...Programmed cell death(PCD)is an essential process for development,and shows conserved cytological features in both plants and animals.Caspases are well-known critical components of the PCD machinery in animals.However,currently few typical counterparts have been identified in plants and only several caspase-like proteases are known to be involved in plant PCD,indicating the existence of great challenge for confirming new caspase-like proteases and elucidating the mechanisms regulating plant PCD.Here,we report a novel cysteine protease,NtTPE8,which was extracted from tobacco seeds and confirmed as a new caspase-like protease.Recombinant NtTPE8 exhibited legumain and caspase-like proteolytic activities,both of which could be inhibited by the pan-caspase inhibitor(Z-VAD-FMK).Notably,NtTPE8 possessed several caspase activities and the capacity to cleave the cathepsin H substrate FVR,indicating a unique character of NtTPE8.NtTPE8 was exclusively expressed in the integumentary tapetum and thus,is the first specific molecular marker reported to date for this cell type.Downregulation of NtTPE8 caused seed abortion,via disturbing early embryogenesis,indicating its critical role in embryogenesis and seed development.In conclusion,we identified a novel caspase-like cysteine protease,NtTPE8,exclusively expressed in the integumentary tapetum that is involved in seed development.展开更多
This editorial critically evaluated the recent study by AlMousa et al,which examined the impact of the Arabic version of the American Academy of Or-thopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)on ...This editorial critically evaluated the recent study by AlMousa et al,which examined the impact of the Arabic version of the American Academy of Or-thopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)on postoperative quality of life and recovery in Arabic-speaking patients with traumatic foot and ankle injuries.In the context of systemic linguistic exclusion in orthopedic research—where English-language journals dominated most publi-cations and non-English-speaking populations faced dual barriers of trial under-representation and semantic distortions(e.g.,mistranslations of terms like"joint instability"in Arabic)—AlMousa et al's work highlighted the transformative po-tential of culturally adapted methodologies.Their rigorous four-stage adaptation framework validated the Arabic AAOS-FAOQ as a reliable tool,enhancing ecological validity and reducing bias in patient-reported outcomes.However,limitations such as regional specificity(Gulf-centric sampling)and short follow-up periods(4 months)underscored broader challenges in non-English research:Redundant studies,prolonged hospital stays for limited English proficiency patients,and underrepresentation of certain ethnic groups in trials.To dismantle linguistic hegemony,we proposed semantic reconstruction(e.g.,integrating culturally specific indicators like"prayer posture"),dialect-aware neural tran-slation,and World Health Organization led terminology standardization.In line with these proposed solutions,AlMousa et al’s study exemplified how language-sensitive adaptations could bridge equity gaps,while future efforts would need to balance cultural specificity with cross-study comparability through AI-driven multilingual databases and policy mandates for cultural adaptation roadmaps.展开更多
Dear Editor,Infertility refers to the inability to conceive after one year of regular unprotected intercourse,and as per the available estimates,close to 50 million couples are being affected worldwide[1].In many comm...Dear Editor,Infertility refers to the inability to conceive after one year of regular unprotected intercourse,and as per the available estimates,close to 50 million couples are being affected worldwide[1].In many communities,infertility is regarded as a sign of personal failure,where individuals are blamed for their inability to conceive[2].It is not an unusual practice that people with infertility are excluded from social rituals like baby showers or functions related to parenthood[2].Women are generally considered solely responsible for the condition,while in reality,it can equally affect men[2].On the other hand,men experiencing infertility are subjected to mockery for a reduced sense of masculinity[3].In many communities and cultures,infertility is viewed as a genuine reason for relationship strain and eventually divorce[2].Amid the fear that people will judge them,many couples hide their infertility struggles,and this further plays an important role in increasing stigma[2,3].Further,in some organizations,employers might not consider infertile persons for promotion under the assumption that they do not have many financial responsibilities[3].展开更多
FCS-like zinc finger(FLZ)gene family members are C2-C2 zinc finger proteins that take part in seed dormancy,resistance to Myzus persicae 1,sucrose signaling and abiotic stresse tolerance.However,their functions,especi...FCS-like zinc finger(FLZ)gene family members are C2-C2 zinc finger proteins that take part in seed dormancy,resistance to Myzus persicae 1,sucrose signaling and abiotic stresse tolerance.However,their functions,especially the molecular mechanism through which FLZs function,are not well understood.In this study,we characterized 120FLZs in wheat and revealed the function and mechanism of TaFLZ54D increasing salt stress tolerance in transgenic wheat.Expression analysis demonstrated that TaFLZ54D can be induced by NaCl treatment and it had the highest expression level under NaCl treatment among the 120 FLZs.Over-expression of TaFLZ54D increased wheat salt stress tolerance and the transgenic plants had higher levels of superoxide dismutase(SOD)and peroxidase(POD)activities and soluble sugar content,but a lower Na^(+)/K^(+)ratio and malondialdehyde(MDA)content than the wild type(WT)plants.Potassium ion transmembrane transporters and serine/threonine kinase inhibitor proteins showed differential expression between Ta FLZ54D transgenic wheat and the WT.Yeast two hybrid and luciferase complementation assays revealed that TaSGT1 and TaPP2C are the proteins that interact directly with TaFLZ54D.In summary,TaFLZ54D enhances salt stress tolerance through interaction with TaSGT1 and TaPP2C to reduce Na^(+)absorption and mitigate oxidative stress.The interaction between TaFLZ54D and TaSGT1,as well as TaPP2C indicated a link between salt stress tolerance of TaFLZ54D and the ubiquitin-mediated degradation of negative regulatory proteins.展开更多
In compliance with“Copyright Law of the People’s Republic of China”,it is agreed by the author(s)of the said article as follows upon signing of this statement:The said article shall be published in Journal of Trans...In compliance with“Copyright Law of the People’s Republic of China”,it is agreed by the author(s)of the said article as follows upon signing of this statement:The said article shall be published in Journal of Trans-lational Neuroscience.The author(s)shall grant the fol-lowing worldwide exclusive rights carried by the said article in different languages to Journal of Translational Neuroscience free of charge:reproductions,distribution,electronic dissemination,translation and compilation.The author(s)authorize(s)Journal of Translational Neu-roscience to register the said article(including all the in-termedia)with the proper copyright authorities.展开更多
Fencing for grazing exclusion is regarded as a traditional and effective method for the natural restoration of degraded alpine steppe,and it effectively promotes plant growth and enhances soil carbon stocks.Arbuscular...Fencing for grazing exclusion is regarded as a traditional and effective method for the natural restoration of degraded alpine steppe,and it effectively promotes plant growth and enhances soil carbon stocks.Arbuscular mycorrhizal fungi(AMF)are essential microorganisms in grassland that play a major role in plant-derived C translocation into the soil.However,the effects of fencing on AMF communities and their contributions to soil carbon sequestration are still unclear.In this study,alpine steppe areas with three different fencing durations(free grazing,medium-term fencing for 5-6 years and long-term fencing for more than 10 years)in the northern Tibetan Plateau were selected to explore the effects of grazing exclusion on AMF communities and their roles in soil carbon sequestration.The results showed that medium-and long-term fencing significantly increased both plant aboveground biomass and soil organic carbon(SOC)content.The AMF community composition varied significantly during different fencing durations,with a dramatic increase in the relative abundance of Glomus but a significant reduction in the relative abundance of Diversispora with longer fencing time.Medium-term fencing significantly increased AMF richness and the ShannonWiener index.Meanwhile,fencing significantly increased hyphal length density(HLD),glomalin-related soil protein(GRSP)and the proportion of macroaggregates(250-2,000μm),all of which contribute positively to SOC.Structural equation modeling revealed that fencing time positively influenced HLD and the AMF community composition,subsequently affecting T-GRSP,which was tightly correlated with SOC.Our findings suggest the potentially important contribution of AMF to SOC sequestration,so more attention should be paid to AMF during alpine steppe fencing,particularly for enhancing the efficiency of degraded grassland restoration efforts.展开更多
In the context of future electron-ion collision experiments,particularly the Electron-Ion Collider(EIC)and the Electron-Ion Collider in China(EicC),investigating exclusive photoproduction processes is of paramount imp...In the context of future electron-ion collision experiments,particularly the Electron-Ion Collider(EIC)and the Electron-Ion Collider in China(EicC),investigating exclusive photoproduction processes is of paramount importance.These processes offer a distinctive opportunity to probe the gluon structure of nuclei across a broad range of Bjorken x,thereby enabling measurements of nuclear shadowing and facilitating the search for gluon saturation and color glass condensates.This study explores the potential of utilizing neutron tagging via the Coulomb excitation of nuclei to precisely determine the impact parameter for exclusive photoproduction in electron-ion collisions.By developing the equivalent photon approximation for fast electrons,this study incorporates a coordinate-space-dependent photon flux distribution to elucidate the relationship between the photon transverse momentum distribution and the collision impact parameter.Furthermore,the differential cross section for Coulomb excitation of nuclei is derived by leveraging the spatial information from the photon flux.Our calculations demonstrate that neutron tagging can significantly alter the impact parameter distributions,thereby providing a robust method for impact parameter manipulation in electron-ion collisions.This study provides valuable insights and strategies for exploring the impact parameter dependence of exclusive photoproduction,offering novel insights for experimental design and data analysis.Ultimately,it enhances our understanding of the gluon distribution within the nucleus.展开更多
The protection system for traditional Chinese medicine(TCM)varieties,as an important policy tool to promote the development of TCM,has a long history of over 30 years,from the promulgation of the“Regulations on the P...The protection system for traditional Chinese medicine(TCM)varieties,as an important policy tool to promote the development of TCM,has a long history of over 30 years,from the promulgation of the“Regulations on the Protection of Traditional Chinese Medicine Varieties”in 1992 to the comprehensive revision of the draft for soliciting opinions in 2022.The TCM protection system evolves to meet the needs of innovative development of TCM.This paper reviews the policy developments in TCM varieties protection,collates protection data(1993 to 2024),and analyzes enterprises application strategies amid impending regulatory changes.展开更多
The growing global population presents a significant challenge to ensuring food security,further compounded by the increasing threat of salinity to agricultural productivity.Wheat,a major staple food providing 20%of t...The growing global population presents a significant challenge to ensuring food security,further compounded by the increasing threat of salinity to agricultural productivity.Wheat,a major staple food providing 20%of the total caloric intake for humans,is susceptible to salinity stress.Developing new salttolerant wheat cultivars using wheat breeding techniques and genetic modifications is crucial to addressing this issue while ensuring the sustainability and efficiency of wheat production systems within the prevailing climate trend.This review overviews the current landscape in this field and explores key mechanisms and associated genetic traits that warrant attention within breeding programs.We contend that traditional approaches to breeding wheat for Na^(+)exclusion have limited applicability across varying soil salinity levels,rendering them inefficient.Moreover,we question current phenotyping approaches,advocating for a shift from whole-plant assessments to cell-based phenotyping platforms.Finally,we propose a broader use of wild wheat relatives and various breeding strategies to tap into their germplasm pool for inclusion in wheat breeding programs.展开更多
Edible plant derived exosome-like nanoparticles(ELNs)have been shown to have multiple nutraceutical functions.However,the diversity of plant materials makes the plant derived ELN study challenging.More efforts are sti...Edible plant derived exosome-like nanoparticles(ELNs)have been shown to have multiple nutraceutical functions.However,the diversity of plant materials makes the plant derived ELN study challenging.More efforts are still needed to explore the feasible isolation methods of edible plant derived ELNs and the possible roles of food-derived ELNs in improving human health.In this study,a size exclusion chromatography based method was compared with the traditional ultracentrifugation method to isolate blueberry derived ELNs(B-ELNs),and the miRNA profile of B-ELNs was analyzed by high-throughput sequencing.A total of 36 miRNAs were found to be enriched in B-ELNs compared with berry tissue,and their potential cross-kingdom human gene targets were further predicted.Results showed that size exclusion chromatography was effective for B-ELN isolation.The most abundant miRNAs in B-ELNs mainly belonged to the miR166 family and miR396 family.Target gene prediction indicated that B-ELNs could potentially regulate pathways related to the human digestive system,immune system and infectious diseases.展开更多
Interference management is one of the most important issues in the device-to-device(D2D)-enabled heterogeneous cellular networks(HetCNets)due to the coexistence of massive cellular and D2D devices in which D2D devices...Interference management is one of the most important issues in the device-to-device(D2D)-enabled heterogeneous cellular networks(HetCNets)due to the coexistence of massive cellular and D2D devices in which D2D devices reuse the cellular spectrum.To alleviate the interference,an efficient interference management way is to set exclusion zones around the cellular receivers.In this paper,we adopt a stochastic geometry approach to analyze the outage probabilities of cellular and D2D users in the D2D-enabled HetCNets.The main difficulties contain three aspects:1)how to model the location randomness of base stations,cellular and D2D users in practical networks;2)how to capture the randomness and interrelation of cellular and D2D transmissions due to the existence of random exclusion zones;3)how to characterize the different types of interference and their impacts on the outage probabilities of cellular and D2D users.We then run extensive Monte-Carlo simulations which manifest that our theoretical model is very accurate.展开更多
Objective:This study aimed to determine the effect of Oketani massage with jasmine oil on improving breast milk production on days 1-3.Materials and Methods:This preexperimental one-group pretest-posttest design was c...Objective:This study aimed to determine the effect of Oketani massage with jasmine oil on improving breast milk production on days 1-3.Materials and Methods:This preexperimental one-group pretest-posttest design was conducted with 44 eligible respondents,selected using an incidental sampling technique.Oketani massage with jasmine oil was conducted once a day for 3 consecutive days.A total of 44 respondents were selected with incidental sampling.Sufficient breast milk production was observed through the frequency of baby urination in 24 h,the frequency of baby defecation in 24 h,the baby’s weight,and the length of time the baby slept or remained calm after breastfeeding.Results:Results showed that Oketani massage using jasmine oil impacted on increasing breast milk production in postpartum on days 1-3(Z=6.633,P=0.000).The baby’s weight in 3 days was increased after intervention compared with intervention before(2858.25±180.62 g vs.2881.66±180.96 g,t=55.33,P=0.000),the baby’s urination frequency was increased after intervention(4.55±0.50 vs.7.20±0.70,t=17.87,P=0.000),the breastfeeding frequency has decreased(10.27±1.42 vs.8.82±0.82,t=6.94,P=0.000),and the time of baby’s sleeping or calming state has increased(5.14±6.46 h vs.8.48±10.24 h,t=2.11,P=0.041).Conclusion:Oketani massage combined with jasmine oil has been shown to be effective on improving breast milk production on days 1-3.展开更多
The spatial pattern of trees is an important feature of forests,and different spatial patterns of trees exhibit different ecological stability.Research has confirmed that natural forests with random patterns have high...The spatial pattern of trees is an important feature of forests,and different spatial patterns of trees exhibit different ecological stability.Research has confirmed that natural forests with random patterns have higher biodiversity and stronger resistance to unstable factors such as pests and diseases.Even if they are disturbed or destroyed by unstable factors such as pests and diseases,they can still recover and rescue themselves;while artificial forests with uniform and clustered patterns have lower biodiversity and are susceptible to unstable factors such as pests and diseases.And once pests and diseases occur,it’s more difficult for them to recover.In order to promote the healthy and stable develop-ment of the forestry industry and protect the diversity of the biological environment,it is necessary to protect the random pattern of natural forests from being destroyed in the process of forest management,while effectively transforming the spatial pattern of artificial forests into a random pattern.Therefore,in order to ensure the convenient and accurate determination of the type of forest spatial pattern,research on methods for determining forest spatial pattern has become particularly important.Based on the theory of uniformity,this study proposes definitions and related theories of included exclusive sphere,included exclusive body,included random pattern,and included uniformity.Under the guidance of the definition of inclusion uniformity and related theories,and by using mathematical method,it is proved that the uniformity of inclusion(CL)is asymptotically subject to the Eq.18,Therefore,the relationship between the included uniformity(CL)and the number of trees in the sample plot was established,and the corresponding relationship formula was obtained,and then the determination of the spatial pattern type of trees was completed by using the corresponding relationship formula.Through rigorous reasoning and case verification,the determination method of forest spatial pattern is effective.展开更多
Appropriate feeding practices are important during infancy for good health, growth and development of infants and children. WHO revised its earlier recommendation of Exclusive Breastfeeding (EBF) of infants from 4 to ...Appropriate feeding practices are important during infancy for good health, growth and development of infants and children. WHO revised its earlier recommendation of Exclusive Breastfeeding (EBF) of infants from 4 to 6 months of age to EBF until about 6 months of age, with the addition of complementary foods thereafter. This recommendation confirms that breast milk alone is sufficient to meet infants’ nutritional requirements for the first 6 months of life. The main objective of this study was to investigate the effect of various feeding practices on the Nutritional status of infants 0 - 12-month-old in the Kumba 1 Sub-Division. A descriptive cross-sectional study was conducted from December 2019 to August 2020. A total of 341 nursing mothers and their infants 0 - 12 months of age were recruited. Socio-demographic factors and the different feeding habits of the children were assessed using a semi-structured questionnaire. Nutritional status was assessed using anthropometric measurements. The overall proportion of infants who exclusively breastfed for 6 months was 69.2% and those who were mix-fed were 30.8% in the study area. The overall prevalence of malnutrition in the population was 61.0%. Among the malnourished children, 53.1% were underweight, 19.6% were wasted and 10.0% were stunted. Though not significant, the prevalence of wasting (21.0%) and underweight (58.3%) was higher among Mix-Fed (MF) children when compared to their EBF counterparts. Feeding practices affected the nutritional status of the infants. Underweight and wasting were observed among infants on Complementary Feeding (CF), although some exclusively breast-fed infants were stunted. Hence, nursing mothers should try as much as possible to practice EBF as recommended by WHO and can practice CF when the child is above six months.展开更多
Introduction: Neonatal mortality remains a major concern in West Africa, and exclusive breastfeeding is recognized as a crucial intervention to promote newborn survival. This study aims to identify the factors influen...Introduction: Neonatal mortality remains a major concern in West Africa, and exclusive breastfeeding is recognized as a crucial intervention to promote newborn survival. This study aims to identify the factors influencing the practice of exclusive breastfeeding among mothers, as well as the perceptions of fathers, in the Boulmiougou health district. Method: This cross-sectional mixed study was conducted between May and July 2022, involving 471 mothers and 103 fathers of children under one year of age. Questionnaires and interviews were used to collect data. Results: The practice of exclusive breastfeeding was observed in 44.6% of mothers surveyed. Logistic regression analysis revealed that mothers older than 26 years have a significantly higher chance of exclusive breastfeeding [adjusted OR = 1.7;95% CI: (1.098 - 2.685);p = 0.019] compared to mothers under 26 years of age. Similarly, mothers with at least three antenatal visits were 2.715 times more likely to perform exclusive breastfeeding than those with less than three antenatal visits [adjusted OR = 2.715, 95% CI: (1.184 - 6.225);p = 0.018]. The vast majority of fathers (76.7%) were informed about exclusive breastfeeding, and 59.5% had a correct definition. The analysis of the father’s perception highlighted a stronger focus on traditional practices in 90.3% of cases than on medical recommendations. Conclusion: In light of these results, it is essential to increase sessions to raise awareness and involve men throughout pregnancy, childbirth and early childhood monitoring about the many benefits of exclusive breastfeeding.展开更多
文摘ZTE Corporation demonstrated video call, video streaming, and ftp services based on LTE-A Coordinated Multipoint （CoMP） technology at ＂Mobile World Congress 2011＂ in Barcelona, Spain. This makes ZTE the first and only telecoms vendor in the world to demonstrate LTE-A CoMP-based services.
文摘Foreign Investors Able to Establish Foreign-exclusively Exhibition Corporations In Feb, Ministry of Commerce issued its 1st decree on temporary regulation for foreign-investing corporations; the regulation allows foreign investors to set up foreign-investing convention & exhibition corporations exclusively or through cooperation with other Chinese corporations, enterprises or organizations. With legal protection on their regulatory management and legal rights, these foreign-investing corporations are in the charge of Department of Foreign Investment Administration, Ministry of Commerce.
文摘Objective: The inexistence of publications on hemoglobin values in the first six months of life gave us the objective of describing these values, month by month in healthy, iron sufficient exclusively breastfed infants. Methods: This was a cross-sectional descriptive study in 306 infants stratified according to age from one to six months, full-term births, weighing ≥2500 g, without intercurrences at birth, serum ferritin levels ≥10 ng/mL, followed by the public health service encouraging and supporting exclusive breastfeeding. An automated counter was used for measuring hemoglobin, and serum ferritin was determined using immunoenzymatic method. Student’s t-test was used to analyze differences between means, and Mann-Whitney test when distribution was non-normal. Level of statistical significance was p 0.05. Results: The hemoglobin values, according to gender, did not differ statistically in the different months;the results are presented without sample division according to gender. Hemoglobin means and standard deviations in g/dL were: 11.7(±1.6), 10.7(±1.5), 10.8(±1.3), 11.6(±1.5), 11.7(±1.7), and 11.8(±1.6), from the first to sixth month respectively. Conclusion: The hemoglobin values obtained in all the first six months of life, based on a healthy, exclusively breastfed infant population, may contribute to the reassessment of reference levels for the diagnosis of anemia in the studied age range.
基金supported by National Natural Science Foundation of China Key Project (31630094)National Natural Science Foundation of China Project (31400171)Young Elite Scientists Sponsorship Program by CAST (YESS) (2015QNRC001)
文摘Programmed cell death(PCD)is an essential process for development,and shows conserved cytological features in both plants and animals.Caspases are well-known critical components of the PCD machinery in animals.However,currently few typical counterparts have been identified in plants and only several caspase-like proteases are known to be involved in plant PCD,indicating the existence of great challenge for confirming new caspase-like proteases and elucidating the mechanisms regulating plant PCD.Here,we report a novel cysteine protease,NtTPE8,which was extracted from tobacco seeds and confirmed as a new caspase-like protease.Recombinant NtTPE8 exhibited legumain and caspase-like proteolytic activities,both of which could be inhibited by the pan-caspase inhibitor(Z-VAD-FMK).Notably,NtTPE8 possessed several caspase activities and the capacity to cleave the cathepsin H substrate FVR,indicating a unique character of NtTPE8.NtTPE8 was exclusively expressed in the integumentary tapetum and thus,is the first specific molecular marker reported to date for this cell type.Downregulation of NtTPE8 caused seed abortion,via disturbing early embryogenesis,indicating its critical role in embryogenesis and seed development.In conclusion,we identified a novel caspase-like cysteine protease,NtTPE8,exclusively expressed in the integumentary tapetum that is involved in seed development.
文摘This editorial critically evaluated the recent study by AlMousa et al,which examined the impact of the Arabic version of the American Academy of Or-thopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)on postoperative quality of life and recovery in Arabic-speaking patients with traumatic foot and ankle injuries.In the context of systemic linguistic exclusion in orthopedic research—where English-language journals dominated most publi-cations and non-English-speaking populations faced dual barriers of trial under-representation and semantic distortions(e.g.,mistranslations of terms like"joint instability"in Arabic)—AlMousa et al's work highlighted the transformative po-tential of culturally adapted methodologies.Their rigorous four-stage adaptation framework validated the Arabic AAOS-FAOQ as a reliable tool,enhancing ecological validity and reducing bias in patient-reported outcomes.However,limitations such as regional specificity(Gulf-centric sampling)and short follow-up periods(4 months)underscored broader challenges in non-English research:Redundant studies,prolonged hospital stays for limited English proficiency patients,and underrepresentation of certain ethnic groups in trials.To dismantle linguistic hegemony,we proposed semantic reconstruction(e.g.,integrating culturally specific indicators like"prayer posture"),dialect-aware neural tran-slation,and World Health Organization led terminology standardization.In line with these proposed solutions,AlMousa et al’s study exemplified how language-sensitive adaptations could bridge equity gaps,while future efforts would need to balance cultural specificity with cross-study comparability through AI-driven multilingual databases and policy mandates for cultural adaptation roadmaps.
文摘Dear Editor,Infertility refers to the inability to conceive after one year of regular unprotected intercourse,and as per the available estimates,close to 50 million couples are being affected worldwide[1].In many communities,infertility is regarded as a sign of personal failure,where individuals are blamed for their inability to conceive[2].It is not an unusual practice that people with infertility are excluded from social rituals like baby showers or functions related to parenthood[2].Women are generally considered solely responsible for the condition,while in reality,it can equally affect men[2].On the other hand,men experiencing infertility are subjected to mockery for a reduced sense of masculinity[3].In many communities and cultures,infertility is viewed as a genuine reason for relationship strain and eventually divorce[2].Amid the fear that people will judge them,many couples hide their infertility struggles,and this further plays an important role in increasing stigma[2,3].Further,in some organizations,employers might not consider infertile persons for promotion under the assumption that they do not have many financial responsibilities[3].
基金supported by the National Natural Science Foundation of China(31871622)the Key R&D Program of Shandong Province,China(2022LZG001)。
文摘FCS-like zinc finger(FLZ)gene family members are C2-C2 zinc finger proteins that take part in seed dormancy,resistance to Myzus persicae 1,sucrose signaling and abiotic stresse tolerance.However,their functions,especially the molecular mechanism through which FLZs function,are not well understood.In this study,we characterized 120FLZs in wheat and revealed the function and mechanism of TaFLZ54D increasing salt stress tolerance in transgenic wheat.Expression analysis demonstrated that TaFLZ54D can be induced by NaCl treatment and it had the highest expression level under NaCl treatment among the 120 FLZs.Over-expression of TaFLZ54D increased wheat salt stress tolerance and the transgenic plants had higher levels of superoxide dismutase(SOD)and peroxidase(POD)activities and soluble sugar content,but a lower Na^(+)/K^(+)ratio and malondialdehyde(MDA)content than the wild type(WT)plants.Potassium ion transmembrane transporters and serine/threonine kinase inhibitor proteins showed differential expression between Ta FLZ54D transgenic wheat and the WT.Yeast two hybrid and luciferase complementation assays revealed that TaSGT1 and TaPP2C are the proteins that interact directly with TaFLZ54D.In summary,TaFLZ54D enhances salt stress tolerance through interaction with TaSGT1 and TaPP2C to reduce Na^(+)absorption and mitigate oxidative stress.The interaction between TaFLZ54D and TaSGT1,as well as TaPP2C indicated a link between salt stress tolerance of TaFLZ54D and the ubiquitin-mediated degradation of negative regulatory proteins.
文摘In compliance with“Copyright Law of the People’s Republic of China”,it is agreed by the author(s)of the said article as follows upon signing of this statement:The said article shall be published in Journal of Trans-lational Neuroscience.The author(s)shall grant the fol-lowing worldwide exclusive rights carried by the said article in different languages to Journal of Translational Neuroscience free of charge:reproductions,distribution,electronic dissemination,translation and compilation.The author(s)authorize(s)Journal of Translational Neu-roscience to register the said article(including all the in-termedia)with the proper copyright authorities.
基金supported by the Second Tibetan Plateau Scientific Expedition and Research Program,China(2019QZKK0304)the National Natural Science Foundation of China(31800380 and 31761123001-1)。
文摘Fencing for grazing exclusion is regarded as a traditional and effective method for the natural restoration of degraded alpine steppe,and it effectively promotes plant growth and enhances soil carbon stocks.Arbuscular mycorrhizal fungi(AMF)are essential microorganisms in grassland that play a major role in plant-derived C translocation into the soil.However,the effects of fencing on AMF communities and their contributions to soil carbon sequestration are still unclear.In this study,alpine steppe areas with three different fencing durations(free grazing,medium-term fencing for 5-6 years and long-term fencing for more than 10 years)in the northern Tibetan Plateau were selected to explore the effects of grazing exclusion on AMF communities and their roles in soil carbon sequestration.The results showed that medium-and long-term fencing significantly increased both plant aboveground biomass and soil organic carbon(SOC)content.The AMF community composition varied significantly during different fencing durations,with a dramatic increase in the relative abundance of Glomus but a significant reduction in the relative abundance of Diversispora with longer fencing time.Medium-term fencing significantly increased AMF richness and the ShannonWiener index.Meanwhile,fencing significantly increased hyphal length density(HLD),glomalin-related soil protein(GRSP)and the proportion of macroaggregates(250-2,000μm),all of which contribute positively to SOC.Structural equation modeling revealed that fencing time positively influenced HLD and the AMF community composition,subsequently affecting T-GRSP,which was tightly correlated with SOC.Our findings suggest the potentially important contribution of AMF to SOC sequestration,so more attention should be paid to AMF during alpine steppe fencing,particularly for enhancing the efficiency of degraded grassland restoration efforts.
基金supported in part by the National Key Research and Development Program of China under Contract No.2022YFA1604900the National Natural Science Foundation of China(NSFC)under Contract No.12175223 and 12005220+1 种基金W.Zha is supported by Anhui Provincial Natural Science Foundation No.2208085J23Youth Innovation Promotion Association of Chinese Academy of Science.
文摘In the context of future electron-ion collision experiments,particularly the Electron-Ion Collider(EIC)and the Electron-Ion Collider in China(EicC),investigating exclusive photoproduction processes is of paramount importance.These processes offer a distinctive opportunity to probe the gluon structure of nuclei across a broad range of Bjorken x,thereby enabling measurements of nuclear shadowing and facilitating the search for gluon saturation and color glass condensates.This study explores the potential of utilizing neutron tagging via the Coulomb excitation of nuclei to precisely determine the impact parameter for exclusive photoproduction in electron-ion collisions.By developing the equivalent photon approximation for fast electrons,this study incorporates a coordinate-space-dependent photon flux distribution to elucidate the relationship between the photon transverse momentum distribution and the collision impact parameter.Furthermore,the differential cross section for Coulomb excitation of nuclei is derived by leveraging the spatial information from the photon flux.Our calculations demonstrate that neutron tagging can significantly alter the impact parameter distributions,thereby providing a robust method for impact parameter manipulation in electron-ion collisions.This study provides valuable insights and strategies for exploring the impact parameter dependence of exclusive photoproduction,offering novel insights for experimental design and data analysis.Ultimately,it enhances our understanding of the gluon distribution within the nucleus.
文摘The protection system for traditional Chinese medicine(TCM)varieties,as an important policy tool to promote the development of TCM,has a long history of over 30 years,from the promulgation of the“Regulations on the Protection of Traditional Chinese Medicine Varieties”in 1992 to the comprehensive revision of the draft for soliciting opinions in 2022.The TCM protection system evolves to meet the needs of innovative development of TCM.This paper reviews the policy developments in TCM varieties protection,collates protection data(1993 to 2024),and analyzes enterprises application strategies amid impending regulatory changes.
基金supported by Australian Research Council,Australia grants to Sergey Shabala and Kadambot H.M.Siddique。
文摘The growing global population presents a significant challenge to ensuring food security,further compounded by the increasing threat of salinity to agricultural productivity.Wheat,a major staple food providing 20%of the total caloric intake for humans,is susceptible to salinity stress.Developing new salttolerant wheat cultivars using wheat breeding techniques and genetic modifications is crucial to addressing this issue while ensuring the sustainability and efficiency of wheat production systems within the prevailing climate trend.This review overviews the current landscape in this field and explores key mechanisms and associated genetic traits that warrant attention within breeding programs.We contend that traditional approaches to breeding wheat for Na^(+)exclusion have limited applicability across varying soil salinity levels,rendering them inefficient.Moreover,we question current phenotyping approaches,advocating for a shift from whole-plant assessments to cell-based phenotyping platforms.Finally,we propose a broader use of wild wheat relatives and various breeding strategies to tap into their germplasm pool for inclusion in wheat breeding programs.
基金supported by the National Natural Science Foundation of China(31701561)。
文摘Edible plant derived exosome-like nanoparticles(ELNs)have been shown to have multiple nutraceutical functions.However,the diversity of plant materials makes the plant derived ELN study challenging.More efforts are still needed to explore the feasible isolation methods of edible plant derived ELNs and the possible roles of food-derived ELNs in improving human health.In this study,a size exclusion chromatography based method was compared with the traditional ultracentrifugation method to isolate blueberry derived ELNs(B-ELNs),and the miRNA profile of B-ELNs was analyzed by high-throughput sequencing.A total of 36 miRNAs were found to be enriched in B-ELNs compared with berry tissue,and their potential cross-kingdom human gene targets were further predicted.Results showed that size exclusion chromatography was effective for B-ELN isolation.The most abundant miRNAs in B-ELNs mainly belonged to the miR166 family and miR396 family.Target gene prediction indicated that B-ELNs could potentially regulate pathways related to the human digestive system,immune system and infectious diseases.
基金This work is funded in part by the Science and Technology Development Fund,Macao SAR(Grant Nos.0093/2022/A2,0076/2022/A2 and 0008/2022/AGJ)in part by the National Nature Science Foundation of China(Grant No.61872452)+3 种基金in part by Special fund for Dongguan’s Rural Revitalization Strategy in 2021(Grant No.20211800400102)in part by Dongguan Special Commissioner Project(Grant No.20211800500182)in part by Guangdong-Dongguan Joint Fund for Basic and Applied Research of Guangdong Province(Grant No.2020A1515110162)in part by University Special Fund of Guangdong Provincial Department of Education(Grant No.2022ZDZX1073).
文摘Interference management is one of the most important issues in the device-to-device(D2D)-enabled heterogeneous cellular networks(HetCNets)due to the coexistence of massive cellular and D2D devices in which D2D devices reuse the cellular spectrum.To alleviate the interference,an efficient interference management way is to set exclusion zones around the cellular receivers.In this paper,we adopt a stochastic geometry approach to analyze the outage probabilities of cellular and D2D users in the D2D-enabled HetCNets.The main difficulties contain three aspects:1)how to model the location randomness of base stations,cellular and D2D users in practical networks;2)how to capture the randomness and interrelation of cellular and D2D transmissions due to the existence of random exclusion zones;3)how to characterize the different types of interference and their impacts on the outage probabilities of cellular and D2D users.We then run extensive Monte-Carlo simulations which manifest that our theoretical model is very accurate.
文摘Objective:This study aimed to determine the effect of Oketani massage with jasmine oil on improving breast milk production on days 1-3.Materials and Methods:This preexperimental one-group pretest-posttest design was conducted with 44 eligible respondents,selected using an incidental sampling technique.Oketani massage with jasmine oil was conducted once a day for 3 consecutive days.A total of 44 respondents were selected with incidental sampling.Sufficient breast milk production was observed through the frequency of baby urination in 24 h,the frequency of baby defecation in 24 h,the baby’s weight,and the length of time the baby slept or remained calm after breastfeeding.Results:Results showed that Oketani massage using jasmine oil impacted on increasing breast milk production in postpartum on days 1-3(Z=6.633,P=0.000).The baby’s weight in 3 days was increased after intervention compared with intervention before(2858.25±180.62 g vs.2881.66±180.96 g,t=55.33,P=0.000),the baby’s urination frequency was increased after intervention(4.55±0.50 vs.7.20±0.70,t=17.87,P=0.000),the breastfeeding frequency has decreased(10.27±1.42 vs.8.82±0.82,t=6.94,P=0.000),and the time of baby’s sleeping or calming state has increased(5.14±6.46 h vs.8.48±10.24 h,t=2.11,P=0.041).Conclusion:Oketani massage combined with jasmine oil has been shown to be effective on improving breast milk production on days 1-3.
基金funded in part by Research on Intelligent Control System of Variable Fertilization of Deep Application Liquid Fertilizer(GXKS2022GKY003)Research on Vehicle Ranging System Based on Object Detection and Monocular Vision(2022KY0854).
文摘The spatial pattern of trees is an important feature of forests,and different spatial patterns of trees exhibit different ecological stability.Research has confirmed that natural forests with random patterns have higher biodiversity and stronger resistance to unstable factors such as pests and diseases.Even if they are disturbed or destroyed by unstable factors such as pests and diseases,they can still recover and rescue themselves;while artificial forests with uniform and clustered patterns have lower biodiversity and are susceptible to unstable factors such as pests and diseases.And once pests and diseases occur,it’s more difficult for them to recover.In order to promote the healthy and stable develop-ment of the forestry industry and protect the diversity of the biological environment,it is necessary to protect the random pattern of natural forests from being destroyed in the process of forest management,while effectively transforming the spatial pattern of artificial forests into a random pattern.Therefore,in order to ensure the convenient and accurate determination of the type of forest spatial pattern,research on methods for determining forest spatial pattern has become particularly important.Based on the theory of uniformity,this study proposes definitions and related theories of included exclusive sphere,included exclusive body,included random pattern,and included uniformity.Under the guidance of the definition of inclusion uniformity and related theories,and by using mathematical method,it is proved that the uniformity of inclusion(CL)is asymptotically subject to the Eq.18,Therefore,the relationship between the included uniformity(CL)and the number of trees in the sample plot was established,and the corresponding relationship formula was obtained,and then the determination of the spatial pattern type of trees was completed by using the corresponding relationship formula.Through rigorous reasoning and case verification,the determination method of forest spatial pattern is effective.
文摘Appropriate feeding practices are important during infancy for good health, growth and development of infants and children. WHO revised its earlier recommendation of Exclusive Breastfeeding (EBF) of infants from 4 to 6 months of age to EBF until about 6 months of age, with the addition of complementary foods thereafter. This recommendation confirms that breast milk alone is sufficient to meet infants’ nutritional requirements for the first 6 months of life. The main objective of this study was to investigate the effect of various feeding practices on the Nutritional status of infants 0 - 12-month-old in the Kumba 1 Sub-Division. A descriptive cross-sectional study was conducted from December 2019 to August 2020. A total of 341 nursing mothers and their infants 0 - 12 months of age were recruited. Socio-demographic factors and the different feeding habits of the children were assessed using a semi-structured questionnaire. Nutritional status was assessed using anthropometric measurements. The overall proportion of infants who exclusively breastfed for 6 months was 69.2% and those who were mix-fed were 30.8% in the study area. The overall prevalence of malnutrition in the population was 61.0%. Among the malnourished children, 53.1% were underweight, 19.6% were wasted and 10.0% were stunted. Though not significant, the prevalence of wasting (21.0%) and underweight (58.3%) was higher among Mix-Fed (MF) children when compared to their EBF counterparts. Feeding practices affected the nutritional status of the infants. Underweight and wasting were observed among infants on Complementary Feeding (CF), although some exclusively breast-fed infants were stunted. Hence, nursing mothers should try as much as possible to practice EBF as recommended by WHO and can practice CF when the child is above six months.
文摘Introduction: Neonatal mortality remains a major concern in West Africa, and exclusive breastfeeding is recognized as a crucial intervention to promote newborn survival. This study aims to identify the factors influencing the practice of exclusive breastfeeding among mothers, as well as the perceptions of fathers, in the Boulmiougou health district. Method: This cross-sectional mixed study was conducted between May and July 2022, involving 471 mothers and 103 fathers of children under one year of age. Questionnaires and interviews were used to collect data. Results: The practice of exclusive breastfeeding was observed in 44.6% of mothers surveyed. Logistic regression analysis revealed that mothers older than 26 years have a significantly higher chance of exclusive breastfeeding [adjusted OR = 1.7;95% CI: (1.098 - 2.685);p = 0.019] compared to mothers under 26 years of age. Similarly, mothers with at least three antenatal visits were 2.715 times more likely to perform exclusive breastfeeding than those with less than three antenatal visits [adjusted OR = 2.715, 95% CI: (1.184 - 6.225);p = 0.018]. The vast majority of fathers (76.7%) were informed about exclusive breastfeeding, and 59.5% had a correct definition. The analysis of the father’s perception highlighted a stronger focus on traditional practices in 90.3% of cases than on medical recommendations. Conclusion: In light of these results, it is essential to increase sessions to raise awareness and involve men throughout pregnancy, childbirth and early childhood monitoring about the many benefits of exclusive breastfeeding.
