A stochastic epidemic model with two age groups is established in this study,in which the susceptible(S),the exposed(E),the infected(I),the hospitalized(H)and the recovered(R)are involved within the total population,t...A stochastic epidemic model with two age groups is established in this study,in which the susceptible(S),the exposed(E),the infected(I),the hospitalized(H)and the recovered(R)are involved within the total population,the aging rates between two age groups are set to be constant.The existence-and-uniqueness of global positive solution is firstly showed.Then,by constructing several appropriate Lyapunov functions and using the high-dimensional Itô’s formula,the sufficient conditions for the stochastic extinction and stochastic persistence of the exposed individuals and the infected individuals are obtained.The stochastic extinction indicator and the stochastic persistence indicator are less-valued expressions compared with the basic reproduction number.Meanwhile,the main results of this study are modified into multi-age groups.Furthermore,by using the surveillance data for Fujian Provincial Center for Disease Control and Prevention,Fuzhou COVID-19 epidemic is chosen to carry out the numerical simulations,which show that the age group of the population plays the vital role when studying infectious diseases.展开更多
In this paper,based on the SVIQR model we develop a stochastic epidemic model with multiple vaccinations and time delay.Firstly,we prove the existence and uniqueness of the global positive solution of the model,and co...In this paper,based on the SVIQR model we develop a stochastic epidemic model with multiple vaccinations and time delay.Firstly,we prove the existence and uniqueness of the global positive solution of the model,and construct suitable functions to obtain sufficient conditions for disease extinction.Secondly,in order to effectively control the spread of the disease,appropriate control strategies are formulated by using optimal control theory.Finally,the results are verified by numerical simulation.展开更多
This paper is devoted to investigating the spreading speed of a time-space periodic epidemic model with vital dynamics and standard incidence in discrete media. We establish the existence of the leftward and rightward...This paper is devoted to investigating the spreading speed of a time-space periodic epidemic model with vital dynamics and standard incidence in discrete media. We establish the existence of the leftward and rightward spreading speeds for the infective individuals, which can be used to estimate how fast the disease spreads. To overcome the difficulty arising from the lack of comparison principle for such time-space periodic nonmonotone systems, our proof is mainly based on constructing a series of scalar time-space periodic equations, establishing the spreading speeds for such auxiliary equations and using comparison methods. It may be the first work to study the spreading speed for time-space periodic non-monotone systems.展开更多
An SIS epidemic model with a simple vaccination is investigated in this article, The efficiency of vaccine, the disease-related death rate and population dynamics are also considered in this model. The authors find tw...An SIS epidemic model with a simple vaccination is investigated in this article, The efficiency of vaccine, the disease-related death rate and population dynamics are also considered in this model. The authors find two threshold R0 and Rc （Rc may not exist）. There is a unique endemic equilibrium for R0 〉 1 or Rc = R0; there are two endemic equilibria for Rc 〈 R0 〈 1; and there is no endemic equilibrium for Rn 〈 Rc 〈 1. When Rc exists, there is a backward bifurcation from the disease-free equilibrium for R0 = 1. They analyze the stability of equilibria and obtain the globally dynamic behaviors of the model. The results acquired in this article show that an accurate estimation of the efficiency of vaccine is necessary to prevent and controll the spread of disease.展开更多
In this article, an SIRS epidemic model spread by vectors （mosquitoes） which have an incubation time to become infectious is formulated. It is shown that a disease-free equilibrium point is globally stable if no end...In this article, an SIRS epidemic model spread by vectors （mosquitoes） which have an incubation time to become infectious is formulated. It is shown that a disease-free equilibrium point is globally stable if no endemic equilibrium point exists. Further, the endemic equilibrium point （if it exists） is globally stable with a respect ＂weak delay＂. Some known results are generalized.展开更多
A disease transmission model of SI type with stage structure is formulated. The stability of disease free equilibrium, the existence and uniqueness of an endemic equilibrium, the existence of a global attractor are in...A disease transmission model of SI type with stage structure is formulated. The stability of disease free equilibrium, the existence and uniqueness of an endemic equilibrium, the existence of a global attractor are investigated.展开更多
In this article, we establish the global stability of an endemic equilibrium of multi-group SIR epidemic models, which have not only an exchange of individuals between patches through migration but also cross patch in...In this article, we establish the global stability of an endemic equilibrium of multi-group SIR epidemic models, which have not only an exchange of individuals between patches through migration but also cross patch infection between different groups. As a result, we partially generalize the recent result in the article [16].展开更多
In this article, we establish the global asymptotic stability of a disease-free equilibrium and an endemic equilibrium of an SIRS epidemic model with a class of nonlin- ear incidence rates and distributed delays. By u...In this article, we establish the global asymptotic stability of a disease-free equilibrium and an endemic equilibrium of an SIRS epidemic model with a class of nonlin- ear incidence rates and distributed delays. By using strict monotonicity of the incidence function and constructing a Lyapunov functional, we obtain sufficient conditions under which the endemic equilibrium is globally asymptotically stable. When the nonlinear inci- dence rate is a saturated incidence rate, our result provides a new global stability condition for a small rate of immunity loss.展开更多
An epidemic models of SIR type and SIRS type with general contact rate and constant immigration of each class were discussed by means of theory of limit system and suitable Liapunov functions. In the absence of input ...An epidemic models of SIR type and SIRS type with general contact rate and constant immigration of each class were discussed by means of theory of limit system and suitable Liapunov functions. In the absence of input of infectious individuals, the threshold of existence of endemic equilibrium is found.For the disease-free equilibrium and the endemic equilibrium of corresponding SIR model, the sufficient and necessary conditions of global asymptotical stabilities are all obtained.For corresponding SIRS model, the sufficient conditions of global asymptotical stabilities of the disease-free equilibrium and the endemic equilibrium are obtained. In the existence of input of infectious individuals, the models have no disease-free equilibrium. For corresponding SIR model, the endemic equilibrium is globally asymptotically stable; for corresponding SIRS model, the sufficient conditions of global asymptotical stability of the endemic equilibrium are obtained.展开更多
We present Turing pattern selection in a reaction-diffusion epidemic model under zero-flux boundary conditions. The value of this study is twofold. First, it establishes the amplitude equations for the excited modes, ...We present Turing pattern selection in a reaction-diffusion epidemic model under zero-flux boundary conditions. The value of this study is twofold. First, it establishes the amplitude equations for the excited modes, which determines the stability of amplitudes towards uniform and inhomogeneous perturbations. Second, it illustrates all five categories of Turing patterns close to the onset of Turing bifurcation via numerical simulations which indicates that the model dynamics exhibits complex pattern replication： on increasing the control parameter v, the sequence ＂H0 hexagons → H0-hexagon-stripe mixtures →stripes → Hπ-hexagon-stripe mixtures → Hπ hexagons＂ is observed. This may enrich the pattern dynamics in a diffusive epidemic model.展开更多
This study aims to improve control schemes for COVID-19 by a numerical model with estimation of parameters.We established a multi-level and multi-objective nonlinear SEIDR model to simulate the virus transmission.The ...This study aims to improve control schemes for COVID-19 by a numerical model with estimation of parameters.We established a multi-level and multi-objective nonlinear SEIDR model to simulate the virus transmission.The early spread in Japan was adopted as a case study.The first 96 days since the infection were divided into five stages with parameters estimated.Then,we analyzed the trend of the parameter value,age structure ratio,and the defined PCR test index(standardization of the scale of PCR tests).It was discovered that the self-healing rate and confirmed rate were linear with the age structure ratio and the PCR test index using the stepwise regression method.The transmission rates were related to the age structure ratio,PCR test index,and isolation efficiency.Both isolation measures and PCR test medical screening can effectively reduce the number of infected cases based on the simulation results.However,the strategy of increasing PCR test medical screening would encountered a bottleneck effect on the virus control when the index reached 0.3.The effectiveness of the policy would decrease and the basic reproduction number reached the extreme value at 0.6.This study gave a feasible combination for isolation and PCR test by simulation.The isolation intensity could be adjusted to compensate the insufficiency of PCR test to control the pandemic.展开更多
This paper considers an SEIS epidemic model with infectious force in the latent period and a general population-size dependent contact rate. A threshold parameter R is identified. If R≤1, the disease-free equilibrium...This paper considers an SEIS epidemic model with infectious force in the latent period and a general population-size dependent contact rate. A threshold parameter R is identified. If R≤1, the disease-free equilibrium O is globally stable. If R〉1, there is a unique endemic equilibrium and O is unstable. For two important special cases of bilinear and standard incidence ,sufficient conditions for the global stability of this endemic equilibrium are given. The same qualitative results are obtained provided the threshold is more than unity for the corresponding SEIS model with no infectious force in the latent period. Some existing results are extended and improved.展开更多
This paper considers an SIRS epidemic model that incorporates constant immigrati on rate, a general population size dependent contact rate and proportional tran sfer rate from the infective class to susceptible class...This paper considers an SIRS epidemic model that incorporates constant immigrati on rate, a general population size dependent contact rate and proportional tran sfer rate from the infective class to susceptible class.A threshold parameter σ is identified. If σ≤1, the disease free equilibrium is globally stab le. If σ>1, a unique endemic equilibrium is locally asymptotically stable. For two important special cases of mass action incidence and standard incidence, global stability of the endemic equilibrium is proved provided the threshold is larger than unity. Some previous results are extended and improved.展开更多
In this paper, we are concerned with a reaction-diffusion SIR epidemic model with nonlinear incidence rate and non-local delay effect in a continuous bounded spatial domain. We introduce the basic reproduction number ...In this paper, we are concerned with a reaction-diffusion SIR epidemic model with nonlinear incidence rate and non-local delay effect in a continuous bounded spatial domain. We introduce the basic reproduction number R_0 of the model by the idea of next generation operator. By means of the theory of dynamical systems and uniform persistence, we investigate the global dynamics of the model in terms of R_0. Finally, we implement numerical simulations to show the feasibility of our results and explore some epidemiological insights.展开更多
By means of limit theory and Fonda＇s theorem, an SEIS epidemic model with constant recruitment and the disease-related rate is considered. The incidence term is of the nonlinear form, and the basic reproduction numbe...By means of limit theory and Fonda＇s theorem, an SEIS epidemic model with constant recruitment and the disease-related rate is considered. The incidence term is of the nonlinear form, and the basic reproduction number is found. If the basic reproduction number is less than one, there exists only the disease-free equilibrium, which is globally asymptotically stable, and the disease dies out eventually. If the basic reproduction number is greater than one, besides the unstable disease-free equilibrium, there exists also a unique endemic equilibrium, which is locally asymptotically stable, and the disease is uniformly persistent.展开更多
We discuss in this paper a deterministic multi-group MSIR epidemic model with a vaccination rate, the basic reproduction number Ro, a key parameter in epidemiology, is a threshold which determines the persistence or e...We discuss in this paper a deterministic multi-group MSIR epidemic model with a vaccination rate, the basic reproduction number Ro, a key parameter in epidemiology, is a threshold which determines the persistence or extinction of the disease. By using Lyapunov function techniques, we show if Ro is greater than 1 and the deterministic model obeys some conditions, then the disease will prevail, the infective persists and the endemic state is asymptotically stable in a feasible region. If Ro is less than or equal to 1, then the infective disappear so the disease dies out. In addition, stochastic noises around the endemic equilibrium will be added to the deterministic MSIR model in order that the deterministic model is extended to a system of stochastic ordinary differential equations. In the stochastic version, we carry out a detailed analysis on the asymptotic behavior of the stochastic model. In addition, regarding the value of Ro, when the stochastic system obeys some conditions and Ro is greater than 1, we deduce the stochastic system is stochastically asymptotically stable. Finally, the deterministic and stochastic model dynamics are illustrated through computer simulations.展开更多
The probability is introduced to formulate the death of individuals, the recovery of the infected individuals and incidence of epidemic disease. Based on the assumption that the number of individuals in a population i...The probability is introduced to formulate the death of individuals, the recovery of the infected individuals and incidence of epidemic disease. Based on the assumption that the number of individuals in a population is a constant, discrete-time SI and SIS epidemic models with vital dynamics are established respectively corresponding to the case that the infectives can recover from the disease or not. For these two models. the results obtained in this paper show that there is the same dynarfiical behavior as their corresponding continuous ones. and the threshold determining its dynamical behavior is found. Below the threshold the epidemic disease dies out eventually, above the threshold the epidemic disease becomes an endemic eventually, and the number of the infectives approaches a positive constant.展开更多
In this paper, to complete the global dynamics of a multi-strains SIS epidemic model, we establish a precise result on coexistence for the cases of the partial and complete duplicated multiple largest reproduction rat...In this paper, to complete the global dynamics of a multi-strains SIS epidemic model, we establish a precise result on coexistence for the cases of the partial and complete duplicated multiple largest reproduction ratios for this model.展开更多
This work aimed to construct an epidemic model with fuzzy parameters.Since the classical epidemic model doesnot elaborate on the successful interaction of susceptible and infective people,the constructed fuzzy epidemi...This work aimed to construct an epidemic model with fuzzy parameters.Since the classical epidemic model doesnot elaborate on the successful interaction of susceptible and infective people,the constructed fuzzy epidemicmodel discusses the more detailed versions of the interactions between infective and susceptible people.Thenext-generation matrix approach is employed to find the reproduction number of a deterministic model.Thesensitivity analysis and local stability analysis of the systemare also provided.For solving the fuzzy epidemic model,a numerical scheme is constructed which consists of three time levels.The numerical scheme has an advantage overthe existing forward Euler scheme for determining the conditions of getting the positive solution.The establishedscheme also has an advantage over existing non-standard finite difference methods in terms of order of accuracy.The stability of the scheme for the considered fuzzy model is also provided.From the plotted results,it can beobserved that susceptible people decay by rising interaction parameters.展开更多
In this research,we propose a new change in classical epidemic models by including the change in the rate of death in the overall population.The existing models like Susceptible-Infected-Recovered(SIR)and Susceptible-...In this research,we propose a new change in classical epidemic models by including the change in the rate of death in the overall population.The existing models like Susceptible-Infected-Recovered(SIR)and Susceptible-Infected-Recovered-Susceptible(SIRS)include the death rate as one of the parameters to estimate the change in susceptible,infected and recovered populations.Actually,because of the deficiencies in immunity,even the ordinary flu could cause death.If people’s disease resistance is strong,then serious diseases may not result in mortalities.The classical model always assumes a closed system where there is no new birth or death,no immigration or emigration,while in reality,such assumptions are not realistic.Moreover,the classical epidemic model does not report the change in population due to death caused by a disease.With this study,we try to incorporate the rate of change in the population of death caused by a disease,where the model is framed to reduce the curve of death along with the susceptible and infected populations.Since the rate of change turned out to be very small,we have tried to estimate it fractionally.Thus,the model is defined using fuzzy logic and is solved by two different methods:a Laplace Adomian decomposition method(LADM)and a differential transform method(DTM)for an arbitrary order α.To test its accuracy,we compared the results of both DTM and LADM with the fourth-order Runge-Kutta method(RKM-4)at α=1.展开更多
基金Supported by National Natural Science Foundation of China(61911530398,12231012)Consultancy Project by the Chinese Academy of Engineering(2022-JB-06,2023-JB-12)+3 种基金the Natural Science Foundation of Fujian Province of China(2021J01621)Special Projects of the Central Government Guiding Local Science and Technology Development(2021L3018)Royal Society of Edinburgh(RSE1832)Engineering and Physical Sciences Research Council(EP/W522521/1).
文摘A stochastic epidemic model with two age groups is established in this study,in which the susceptible(S),the exposed(E),the infected(I),the hospitalized(H)and the recovered(R)are involved within the total population,the aging rates between two age groups are set to be constant.The existence-and-uniqueness of global positive solution is firstly showed.Then,by constructing several appropriate Lyapunov functions and using the high-dimensional Itô’s formula,the sufficient conditions for the stochastic extinction and stochastic persistence of the exposed individuals and the infected individuals are obtained.The stochastic extinction indicator and the stochastic persistence indicator are less-valued expressions compared with the basic reproduction number.Meanwhile,the main results of this study are modified into multi-age groups.Furthermore,by using the surveillance data for Fujian Provincial Center for Disease Control and Prevention,Fuzhou COVID-19 epidemic is chosen to carry out the numerical simulations,which show that the age group of the population plays the vital role when studying infectious diseases.
基金supported by the Fundamental Research Funds for the Central Universities(No.3122025090)。
文摘In this paper,based on the SVIQR model we develop a stochastic epidemic model with multiple vaccinations and time delay.Firstly,we prove the existence and uniqueness of the global positive solution of the model,and construct suitable functions to obtain sufficient conditions for disease extinction.Secondly,in order to effectively control the spread of the disease,appropriate control strategies are formulated by using optimal control theory.Finally,the results are verified by numerical simulation.
基金supported by the Natural Science Basic Research Program of Shanxi(Grant No.2024JC-YBMS-025)the Innovation Capability Support Program of Shanxi(Grant No.2024RS-CXTD-88)。
文摘This paper is devoted to investigating the spreading speed of a time-space periodic epidemic model with vital dynamics and standard incidence in discrete media. We establish the existence of the leftward and rightward spreading speeds for the infective individuals, which can be used to estimate how fast the disease spreads. To overcome the difficulty arising from the lack of comparison principle for such time-space periodic nonmonotone systems, our proof is mainly based on constructing a series of scalar time-space periodic equations, establishing the spreading speeds for such auxiliary equations and using comparison methods. It may be the first work to study the spreading speed for time-space periodic non-monotone systems.
基金Supported by the Nature Science Foundation of China(19971066)Postdoctoral Foundation of China(2005037785)
文摘An SIS epidemic model with a simple vaccination is investigated in this article, The efficiency of vaccine, the disease-related death rate and population dynamics are also considered in this model. The authors find two threshold R0 and Rc （Rc may not exist）. There is a unique endemic equilibrium for R0 〉 1 or Rc = R0; there are two endemic equilibria for Rc 〈 R0 〈 1; and there is no endemic equilibrium for Rn 〈 Rc 〈 1. When Rc exists, there is a backward bifurcation from the disease-free equilibrium for R0 = 1. They analyze the stability of equilibria and obtain the globally dynamic behaviors of the model. The results acquired in this article show that an accurate estimation of the efficiency of vaccine is necessary to prevent and controll the spread of disease.
基金This work is supported by the National Sciences Foundation of China (10471040)the Youth Science Foundations of Shanxi Province (20021003).
文摘In this article, an SIRS epidemic model spread by vectors （mosquitoes） which have an incubation time to become infectious is formulated. It is shown that a disease-free equilibrium point is globally stable if no endemic equilibrium point exists. Further, the endemic equilibrium point （if it exists） is globally stable with a respect ＂weak delay＂. Some known results are generalized.
基金This work is supported by National Natural Science Foundation of China (10171106)the Special Fund for Major State Basic Research Projects (G1999032805)
文摘A disease transmission model of SI type with stage structure is formulated. The stability of disease free equilibrium, the existence and uniqueness of an endemic equilibrium, the existence of a global attractor are investigated.
基金supported by Japan Society for the Promotion of Science (Grant Scientific Research (c), No. 24540219 to the first author, JSPS Fellows, No.237213 to the second author, and No. 222176 to the third author)
文摘In this article, we establish the global stability of an endemic equilibrium of multi-group SIR epidemic models, which have not only an exchange of individuals between patches through migration but also cross patch infection between different groups. As a result, we partially generalize the recent result in the article [16].
基金supported in part by JSPS Fellows,No.237213 of Japan Society for the Promotion of Science to the first authorthe Grant MTM2010-18318 of the MICINN,Spanish Ministry of Science and Innovation to the second authorScientific Research (c),No.21540230 of Japan Society for the Promotion of Science to the third author
文摘In this article, we establish the global asymptotic stability of a disease-free equilibrium and an endemic equilibrium of an SIRS epidemic model with a class of nonlin- ear incidence rates and distributed delays. By using strict monotonicity of the incidence function and constructing a Lyapunov functional, we obtain sufficient conditions under which the endemic equilibrium is globally asymptotically stable. When the nonlinear inci- dence rate is a saturated incidence rate, our result provides a new global stability condition for a small rate of immunity loss.
文摘An epidemic models of SIR type and SIRS type with general contact rate and constant immigration of each class were discussed by means of theory of limit system and suitable Liapunov functions. In the absence of input of infectious individuals, the threshold of existence of endemic equilibrium is found.For the disease-free equilibrium and the endemic equilibrium of corresponding SIR model, the sufficient and necessary conditions of global asymptotical stabilities are all obtained.For corresponding SIRS model, the sufficient conditions of global asymptotical stabilities of the disease-free equilibrium and the endemic equilibrium are obtained. In the existence of input of infectious individuals, the models have no disease-free equilibrium. For corresponding SIR model, the endemic equilibrium is globally asymptotically stable; for corresponding SIRS model, the sufficient conditions of global asymptotical stability of the endemic equilibrium are obtained.
基金Project supported by the Natural Science Foundation of Zhejiang Province of China (Grant No.Y7080041)
文摘We present Turing pattern selection in a reaction-diffusion epidemic model under zero-flux boundary conditions. The value of this study is twofold. First, it establishes the amplitude equations for the excited modes, which determines the stability of amplitudes towards uniform and inhomogeneous perturbations. Second, it illustrates all five categories of Turing patterns close to the onset of Turing bifurcation via numerical simulations which indicates that the model dynamics exhibits complex pattern replication： on increasing the control parameter v, the sequence ＂H0 hexagons → H0-hexagon-stripe mixtures →stripes → Hπ-hexagon-stripe mixtures → Hπ hexagons＂ is observed. This may enrich the pattern dynamics in a diffusive epidemic model.
基金National Natural Science Foundation of China under Grant Nos.61803152,31920103016,and 11871475Doctoral Start-Up Foundation of Hunan Normal University under Grant No.0531120-3827Hunan Provincial Education Department under Grant No.HNKCSZ-2020-0813.
文摘This study aims to improve control schemes for COVID-19 by a numerical model with estimation of parameters.We established a multi-level and multi-objective nonlinear SEIDR model to simulate the virus transmission.The early spread in Japan was adopted as a case study.The first 96 days since the infection were divided into five stages with parameters estimated.Then,we analyzed the trend of the parameter value,age structure ratio,and the defined PCR test index(standardization of the scale of PCR tests).It was discovered that the self-healing rate and confirmed rate were linear with the age structure ratio and the PCR test index using the stepwise regression method.The transmission rates were related to the age structure ratio,PCR test index,and isolation efficiency.Both isolation measures and PCR test medical screening can effectively reduce the number of infected cases based on the simulation results.However,the strategy of increasing PCR test medical screening would encountered a bottleneck effect on the virus control when the index reached 0.3.The effectiveness of the policy would decrease and the basic reproduction number reached the extreme value at 0.6.This study gave a feasible combination for isolation and PCR test by simulation.The isolation intensity could be adjusted to compensate the insufficiency of PCR test to control the pandemic.
文摘This paper considers an SEIS epidemic model with infectious force in the latent period and a general population-size dependent contact rate. A threshold parameter R is identified. If R≤1, the disease-free equilibrium O is globally stable. If R〉1, there is a unique endemic equilibrium and O is unstable. For two important special cases of bilinear and standard incidence ,sufficient conditions for the global stability of this endemic equilibrium are given. The same qualitative results are obtained provided the threshold is more than unity for the corresponding SEIS model with no infectious force in the latent period. Some existing results are extended and improved.
基金Supported by the Science and Technology Foundation of Zhejiang University(1 0 70 0 0 - 54430 1 )
文摘This paper considers an SIRS epidemic model that incorporates constant immigrati on rate, a general population size dependent contact rate and proportional tran sfer rate from the infective class to susceptible class.A threshold parameter σ is identified. If σ≤1, the disease free equilibrium is globally stab le. If σ>1, a unique endemic equilibrium is locally asymptotically stable. For two important special cases of mass action incidence and standard incidence, global stability of the endemic equilibrium is proved provided the threshold is larger than unity. Some previous results are extended and improved.
基金Supported by the Science and Technology Planed Projects of Gansu Province(18JR3RA217)Science Research Foundation for Higher Education Institutions of Gansu Province(2018B-032)
文摘In this paper, we are concerned with a reaction-diffusion SIR epidemic model with nonlinear incidence rate and non-local delay effect in a continuous bounded spatial domain. We introduce the basic reproduction number R_0 of the model by the idea of next generation operator. By means of the theory of dynamical systems and uniform persistence, we investigate the global dynamics of the model in terms of R_0. Finally, we implement numerical simulations to show the feasibility of our results and explore some epidemiological insights.
基金Project supported by the National Key Technologies R & D Program of China (No.2004BA719A01)
文摘By means of limit theory and Fonda＇s theorem, an SEIS epidemic model with constant recruitment and the disease-related rate is considered. The incidence term is of the nonlinear form, and the basic reproduction number is found. If the basic reproduction number is less than one, there exists only the disease-free equilibrium, which is globally asymptotically stable, and the disease dies out eventually. If the basic reproduction number is greater than one, besides the unstable disease-free equilibrium, there exists also a unique endemic equilibrium, which is locally asymptotically stable, and the disease is uniformly persistent.
基金supported by the National Natural Science Foundation of China(Grant No.11326078)the Project of Science and Technology of Heilongjiang Province of China(Grant No.12531187)
文摘We discuss in this paper a deterministic multi-group MSIR epidemic model with a vaccination rate, the basic reproduction number Ro, a key parameter in epidemiology, is a threshold which determines the persistence or extinction of the disease. By using Lyapunov function techniques, we show if Ro is greater than 1 and the deterministic model obeys some conditions, then the disease will prevail, the infective persists and the endemic state is asymptotically stable in a feasible region. If Ro is less than or equal to 1, then the infective disappear so the disease dies out. In addition, stochastic noises around the endemic equilibrium will be added to the deterministic MSIR model in order that the deterministic model is extended to a system of stochastic ordinary differential equations. In the stochastic version, we carry out a detailed analysis on the asymptotic behavior of the stochastic model. In addition, regarding the value of Ro, when the stochastic system obeys some conditions and Ro is greater than 1, we deduce the stochastic system is stochastically asymptotically stable. Finally, the deterministic and stochastic model dynamics are illustrated through computer simulations.
基金Project supported by the National Natural Science Foundation of China(Nos.10531030,10701053)the Natural Science Foundation of Shanxi Province of China(No.2005Z010)
文摘The probability is introduced to formulate the death of individuals, the recovery of the infected individuals and incidence of epidemic disease. Based on the assumption that the number of individuals in a population is a constant, discrete-time SI and SIS epidemic models with vital dynamics are established respectively corresponding to the case that the infectives can recover from the disease or not. For these two models. the results obtained in this paper show that there is the same dynarfiical behavior as their corresponding continuous ones. and the threshold determining its dynamical behavior is found. Below the threshold the epidemic disease dies out eventually, above the threshold the epidemic disease becomes an endemic eventually, and the number of the infectives approaches a positive constant.
文摘In this paper, to complete the global dynamics of a multi-strains SIS epidemic model, we establish a precise result on coexistence for the cases of the partial and complete duplicated multiple largest reproduction ratios for this model.
基金the support of Prince Sultan University for paying the article processing charges(APC)of this publication.
文摘This work aimed to construct an epidemic model with fuzzy parameters.Since the classical epidemic model doesnot elaborate on the successful interaction of susceptible and infective people,the constructed fuzzy epidemicmodel discusses the more detailed versions of the interactions between infective and susceptible people.Thenext-generation matrix approach is employed to find the reproduction number of a deterministic model.Thesensitivity analysis and local stability analysis of the systemare also provided.For solving the fuzzy epidemic model,a numerical scheme is constructed which consists of three time levels.The numerical scheme has an advantage overthe existing forward Euler scheme for determining the conditions of getting the positive solution.The establishedscheme also has an advantage over existing non-standard finite difference methods in terms of order of accuracy.The stability of the scheme for the considered fuzzy model is also provided.From the plotted results,it can beobserved that susceptible people decay by rising interaction parameters.
文摘In this research,we propose a new change in classical epidemic models by including the change in the rate of death in the overall population.The existing models like Susceptible-Infected-Recovered(SIR)and Susceptible-Infected-Recovered-Susceptible(SIRS)include the death rate as one of the parameters to estimate the change in susceptible,infected and recovered populations.Actually,because of the deficiencies in immunity,even the ordinary flu could cause death.If people’s disease resistance is strong,then serious diseases may not result in mortalities.The classical model always assumes a closed system where there is no new birth or death,no immigration or emigration,while in reality,such assumptions are not realistic.Moreover,the classical epidemic model does not report the change in population due to death caused by a disease.With this study,we try to incorporate the rate of change in the population of death caused by a disease,where the model is framed to reduce the curve of death along with the susceptible and infected populations.Since the rate of change turned out to be very small,we have tried to estimate it fractionally.Thus,the model is defined using fuzzy logic and is solved by two different methods:a Laplace Adomian decomposition method(LADM)and a differential transform method(DTM)for an arbitrary order α.To test its accuracy,we compared the results of both DTM and LADM with the fourth-order Runge-Kutta method(RKM-4)at α=1.
